Metabolomic Quantitative Trait Loci (mQTL) Mapping Implicates the Ubiquitin Proteasome System in Cardiovascular Disease Pathogenesis

PLoS Genetics

Volumn 11, Issue 11, 2015, Pages

  Kraus, William E ^a   Muoio, Deborah M ^a   Stevens, Robert ^a   Craig, Damian ^a   Bain, James R ^a   Grass, Elizabeth ^a   Haynes, Carol ^a   Kwee, Lydia ^a   Qin, Xuejun ^a   Slentz, Dorothy H ^a   Krupp, Deidre ^a   Muehlbauer, Michael ^a   Hauser, Elizabeth R ^a   Gregory, Simon G ^a   Newgard, Christopher B ^a   Shah, Svati H ^a  

^a DUKE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACYLCARNITINE; FATTY ACID; GLUCOSE REGULATED PROTEIN 78; PROTEASOME; SHORT CHAIN DICARBOXYLACYLCARNITINE; STROMAL INTERACTION MOLECULE 1; UBIQUITIN; UNCLASSIFIED DRUG; CARNITINE;

ADULT; ARTICLE; BRSK2 GENE; CARDIOVASCULAR DISEASE; CONTROLLED STUDY; ENDOPLASMIC RETICULUM STRESS; FBXO25 GENE; FEMALE; GENE; GENE EXPRESSION; GENE LOCUS; GENETIC ASSOCIATION; GENETIC MARKER; GENETIC VARIABILITY; HERC1 GENE; HOOK2 GENE; HUMAN; HUMAN CELL; MAJOR CLINICAL STUDY; MALE; METABOLITE; METABOLOMIC QUANTITATIVE TRAIT LOCUS; METABOLOMICS; METHYLATION; PATHOGENESIS; QUANTITATIVE TRAIT LOCUS; QUANTITATIVE TRAIT LOCUS MAPPING; SEL1L GENE; STIM1 GENE; SUGT1 GENE; USP3 GENE; ANALOGS AND DERIVATIVES; DNA METHYLATION; GENETICS; METABOLISM; PATHOLOGY; RISK FACTOR; SINGLE NUCLEOTIDE POLYMORPHISM;

CARDIOVASCULAR DISEASES; CARNITINE; DNA METHYLATION; ENDOPLASMIC RETICULUM STRESS; HUMANS; METABOLOMICS; POLYMORPHISM, SINGLE NUCLEOTIDE; PROTEASOME ENDOPEPTIDASE COMPLEX; QUANTITATIVE TRAIT LOCI; RISK FACTORS; UBIQUITIN;

EID: 84949255712     PISSN: 15537390     EISSN: 15537404     Source Type: Journal    
DOI: 10.1371/journal.pgen.1005553     Document Type: Article

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