Systemic inflammation sensitizes the neonatal brain to excitotoxicity through a pro-/anti-inflammatory imbalance: Key role of TNFα pathway and protection by etanercept

Brain, Behavior, and Immunity

Volumn 24, Issue 5, 2010, Pages 747-758

  Ådén, Ulrika ^a,b   Favrais, Géraldine ^a,c,d,e   Plaisant, Frank ^a,c,d   Winerdal, Max ^b   Felderhoff Mueser, Ursula ^f   Lampa, Jon ^g   Lelièvre, Vincent ^a,c,d   Gressens, Pierre ^a,c,d,h  

^a INSERM   (France)

^b KAROLINSKA UNIVERSITY HOSPITAL   (Sweden)

^c UNIVERSITÉ PARIS DESCARTES   (France)

^d PremUP   (France)

^e UNIVERSITÉ DE TOURS   (France)

^f UNIVERSITY HOSPITAL ESSEN   (Germany)

^g KAROLINSKA INSTITUTE   (Sweden)

^h IMPERIAL COLLEGE LONDON   (United Kingdom)

Author keywords

Cerebral palsy; IL 1 ; IL 10; Microglia; Neuroprotection

Indexed keywords

CYTOKINE; ETANERCEPT; IBOTENIC ACID; INTERLEUKIN 10; INTERLEUKIN 1BETA; INTERLEUKIN 6; TUMOR NECROSIS FACTOR ALPHA; TUMOR NECROSIS FACTOR RECEPTOR 1;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BLOOD BRAIN BARRIER; BRAIN DAMAGE; CEREBRAL PALSY; CONTROLLED STUDY; DRUG MECHANISM; ENZYME LINKED IMMUNOSORBENT ASSAY; EXCITOTOXICITY; FEMALE; GENE DELETION; INFLAMMATION; MALE; MICROGLIA; MOUSE; NEUROPROTECTION; NEWBORN; NONHUMAN; PERINATAL PERIOD; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; PROTEIN FUNCTION; PROTEIN INDUCTION; PROTEIN SYNTHESIS; QUANTITATIVE ANALYSIS; RISK REDUCTION; SENSITIZATION; WESTERN BLOTTING;

ANIMALS; ANTIGENS, CD45; BLOTTING, WESTERN; BRAIN; BRAIN INJURIES; CALCIUM-BINDING PROTEINS; CASPASE 3; ENZYME-LINKED IMMUNOSORBENT ASSAY; FEMALE; IBOTENIC ACID; IMMUNOGLOBULIN G; IMMUNOLOGIC FACTORS; INFLAMMATION; INTERLEUKIN-10; INTERLEUKIN-1BETA; INTERLEUKIN-2; MALE; MICE; PLANT LECTINS; RECEPTORS, TUMOR NECROSIS FACTOR; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; STATISTICS, NONPARAMETRIC; TUMOR NECROSIS FACTOR-ALPHA;

EID: 77953618733     PISSN: 08891591     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bbi.2009.10.010     Document Type: Article

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