-
1
-
-
79951596628
-
Challenges in infant immunity: Implications for responses to infection and vaccines
-
PrabhuDas, M. et al. Challenges in infant immunity: implications for responses to infection and vaccines. Nat. Immunol. 12, 189-194 (2011).
-
(2011)
Nat. Immunol.
, vol.12
, pp. 189-194
-
-
PrabhuDas, M.1
-
2
-
-
84925394755
-
Immune mechanisms at the maternal-fetal interface: Perspectives and challenges
-
PrabhuDas, M. et al. Immune mechanisms at the maternal-fetal interface: perspectives and challenges. Nat. Immunol. 16, 328-334 (2015).
-
(2015)
Nat. Immunol.
, vol.16
, pp. 328-334
-
-
PrabhuDas, M.1
-
3
-
-
63149126030
-
Towards an understanding of the adjuvant action of aluminium
-
Marrack, P., McKee, A. S. & Munks, M. W. Towards an understanding of the adjuvant action of aluminium. Nat. Rev. Immunol. 9, 287-293 (2009).
-
(2009)
Nat. Rev. Immunol.
, vol.9
, pp. 287-293
-
-
Marrack, P.1
McKee, A.S.2
Munks, M.W.3
-
4
-
-
84855487703
-
Highly potent human hematopoietic stem cells first emerge in the intraembryonic aorta- gonad-mesonephros region
-
Ivanovs, A. et al. Highly potent human hematopoietic stem cells first emerge in the intraembryonic aorta- gonad-mesonephros region. J. Exp. Med. 208, 2417-2427 (2011).
-
(2011)
J. Exp. Med.
, vol.208
, pp. 2417-2427
-
-
Ivanovs, A.1
-
5
-
-
0029443560
-
Early ontogeny of the human hematopoietic system [in French]
-
Charbord, P. et al. Early ontogeny of the human hematopoietic system [in French]. C. R. Seances Soc. Biol. Fil. 189, 601-609 (1995).
-
(1995)
C. R. Seances Soc. Biol. Fil.
, vol.189
, pp. 601-609
-
-
Charbord, P.1
-
6
-
-
0024330995
-
Hematopoiesis in the fetus and neonate
-
Christensen, R. D. Hematopoiesis in the fetus and neonate. Pediatr. Res. 26, 531-532 (1989).
-
(1989)
Pediatr. Res.
, vol.26
, pp. 531-532
-
-
Christensen, R.D.1
-
7
-
-
0033866604
-
The development of the immune system during pregnancy and early life
-
Holt, P. G. & Jones, C. A. The development of the immune system during pregnancy and early life. Allergy 55, 688-697 (2000).
-
(2000)
Allergy
, vol.55
, pp. 688-697
-
-
Holt, P.G.1
Jones, C.A.2
-
8
-
-
0022474620
-
Human embryonic hemopoiesis. Kinetics of progenitors and precursors underlying the yolk sac-liver transition
-
Migliaccio, G. et al. Human embryonic hemopoiesis. Kinetics of progenitors and precursors underlying the yolk sac-liver transition. J. Clin. Invest. 78, 51-60 (1986).
-
(1986)
J. Clin. Invest.
, vol.78
, pp. 51-60
-
-
Migliaccio, G.1
-
9
-
-
84861127509
-
Immunological tolerance during fetal development: From mouse to man
-
Mold, J. E. & McCune, J. M. Immunological tolerance during fetal development: from mouse to man. Adv. Immunol. 115, 73-111 (2012).
-
(2012)
Adv. Immunol.
, vol.115
, pp. 73-111
-
-
Mold, J.E.1
McCune, J.M.2
-
10
-
-
84919415084
-
Ontogeny of myeloid cells
-
De Kleer, I., Willems, F., Lambrecht, B. & Goriely, S. Ontogeny of myeloid cells. Front. Immunol. 5, 423 (2014).
-
(2014)
Front. Immunol.
, vol.5
, pp. 423
-
-
De Kleer, I.1
Willems, F.2
Lambrecht, B.3
Goriely, S.4
-
11
-
-
0029054386
-
Neutrophil pool sizes and granulocyte colony-stimulating factor production in human mid-trimester fetuses
-
Ohls, R. K. et al. Neutrophil pool sizes and granulocyte colony-stimulating factor production in human mid-trimester fetuses. Pediatr. Res. 37, 806-811 (1995).
-
(1995)
Pediatr. Res.
, vol.37
, pp. 806-811
-
-
Ohls, R.K.1
-
12
-
-
0028899135
-
Early human T cell development: Analysis of the human thymus at the time of initial entry of hematopoietic stem cells into the fetal thymic microenvironment
-
Haynes, B. F. & Heinly, C. S. Early human T cell development: analysis of the human thymus at the time of initial entry of hematopoietic stem cells into the fetal thymic microenvironment. J. Exp. Med. 181, 1445-1458 (1995).
-
(1995)
J. Exp. Med.
, vol.181
, pp. 1445-1458
-
-
Haynes, B.F.1
Heinly, C.S.2
-
13
-
-
0022354486
-
Human T cell antigen expression during the early stages of fetal thymic maturation
-
Lobach, D. F., Hensley, L. L., Ho, W. & Haynes, B. F. Human T cell antigen expression during the early stages of fetal thymic maturation. J. Immunol. 135, 1752-1759 (1985).
-
(1985)
J. Immunol.
, vol.135
, pp. 1752-1759
-
-
Lobach, D.F.1
Hensley, L.L.2
Ho, W.3
Haynes, B.F.4
-
14
-
-
0032250194
-
The human thymus. A chimeric organ comprised of central and peripheral lymphoid components
-
Haynes, B. F. & Hale, L. P. The human thymus. A chimeric organ comprised of central and peripheral lymphoid components. Immunol. Res. 18, 175-192 (1998).
-
(1998)
Immunol. Res.
, vol.18
, pp. 175-192
-
-
Haynes, B.F.1
Hale, L.P.2
-
15
-
-
0242335310
-
Development of the newborn immune system. (in French)
-
Millet, V. et al. Development of the newborn immune system. (in French) Arch. Pediatr. 6 (Suppl. 1), 14S-19S (1999).
-
(1999)
Arch. Pediatr.
, vol.6
, pp. 14S-19S
-
-
Millet, V.1
-
16
-
-
0022630860
-
Ontogenic development of T and B cells and non-lymphoid cells in the white pulp of human spleen
-
Namikawa, R. et al. Ontogenic development of T and B cells and non-lymphoid cells in the white pulp of human spleen. Immunology 57, 61-69 (1986).
-
(1986)
Immunology
, vol.57
, pp. 61-69
-
-
Namikawa, R.1
-
17
-
-
0023110564
-
And neonatal development of human spleen: An immunohistological study
-
Timens, W., Rozeboom, T. & Poppema, S. Fetal and neonatal development of human spleen: an immunohistological study. Immunology 60, 603-609 (1987).
-
(1987)
Immunology
, vol.60
, pp. 603-609
-
-
Timens, W.1
Rozeboom, T.2
Fetal, P.S.3
-
18
-
-
14744287197
-
Development and activation of regulatory T cells in the human fetus
-
Cupedo, T., Nagasawa, M., Weijer, K., Blom, B. & Spits, H. Development and activation of regulatory T cells in the human fetus. Eur. J. Immunol. 35, 383-390 (2005).
-
(2005)
Eur. J. Immunol.
, vol.35
, pp. 383-390
-
-
Cupedo, T.1
Nagasawa, M.2
Weijer, K.3
Blom, B.4
Spits, H.5
-
19
-
-
84905747185
-
A microRNA profile of human CD8+ regulatory T cells and characterization of the effects of microRNAs on Treg cell-associated genes
-
Jebbawi, F. et al. A microRNA profile of human CD8+ regulatory T cells and characterization of the effects of microRNAs on Treg cell-associated genes. J. Transl Med. 12, 218 (2014).
-
(2014)
J. Transl Med.
, vol.12
, pp. 218
-
-
Jebbawi, F.1
-
20
-
-
78650352931
-
Fetal and adult hematopoietic stem cells give rise to distinct T cell lineages in humans
-
Mold, J. E. et al. Fetal and adult hematopoietic stem cells give rise to distinct T cell lineages in humans. Science 330, 1695-1699 (2010).
-
(2010)
Science
, vol.330
, pp. 1695-1699
-
-
Mold, J.E.1
-
21
-
-
57349108583
-
Maternal alloantigens promote the development of tolerogenic fetal regulatory T cells in utero
-
Mold, J. E. et al. Maternal alloantigens promote the development of tolerogenic fetal regulatory T cells in utero. Science 322, 1562-1565 (2008).
-
(2008)
Science
, vol.322
, pp. 1562-1565
-
-
Mold, J.E.1
-
22
-
-
33646486379
-
Regulation of T cell responses in the developing human fetus
-
Michaelsson, J., Mold, J. E., McCune, J. M. & Nixon, D. F. Regulation of T cell responses in the developing human fetus. J. Immunol. 176, 5741-5748 (2006).
-
(2006)
J. Immunol.
, vol.176
, pp. 5741-5748
-
-
Michaelsson, J.1
Mold, J.E.2
McCune, J.M.3
Nixon, D.F.4
-
23
-
-
0028226640
-
A novel subpopulation of primed T cells in the human fetus
-
Byrne, J. A., Stankovic, A. K. & Cooper, M. D. A novel subpopulation of primed T cells in the human fetus. J. Immunol. 152, 3098-3106 (1994).
-
(1994)
J. Immunol.
, vol.152
, pp. 3098-3106
-
-
Byrne, J.A.1
Stankovic, A.K.2
Cooper, M.D.3
-
24
-
-
84869765093
-
Memory CD4+CCR5+ T cells are abundantly present in the gut of newborn infants to facilitate mother-to-child transmission of HIV-1
-
Bunders, M. J. et al. Memory CD4+CCR5+ T cells are abundantly present in the gut of newborn infants to facilitate mother-to-child transmission of HIV-1. Blood 120, 4383-4390 (2012).
-
(2012)
Blood
, vol.120
, pp. 4383-4390
-
-
Bunders, M.J.1
-
25
-
-
84867873461
-
Phenotypic characterization of leukocytes in prenatal human dermis
-
Schuster, C. et al. Phenotypic characterization of leukocytes in prenatal human dermis. J. Invest. Dermatol. 132, 2581-2592 (2012).
-
(2012)
J. Invest. Dermatol.
, vol.132
, pp. 2581-2592
-
-
Schuster, C.1
-
26
-
-
84905098795
-
Human innate lymphoid cells
-
Hazenberg, M. D. & Spits, H. Human innate lymphoid cells. Blood 124, 700-709 (2014).
-
(2014)
Blood
, vol.124
, pp. 700-709
-
-
Hazenberg, M.D.1
Spits, H.2
-
27
-
-
84903693481
-
GATA binding protein 3+ group 2 innate lymphoid cells are present in cord blood and in higher proportions in male than in female neonates
-
Forsberg, A. et al. GATA binding protein 3+ group 2 innate lymphoid cells are present in cord blood and in higher proportions in male than in female neonates. J. Allergy Clin. Immunol. 134, 228-230 (2014).
-
(2014)
J. Allergy Clin. Immunol.
, vol.134
, pp. 228-230
-
-
Forsberg, A.1
-
29
-
-
84946055529
-
Respiratory syncytial virus disease is mediated by age-variable IL-33
-
Saravia, J. et al. Respiratory syncytial virus disease is mediated by age-variable IL-33. PLoS Pathog. 11, e1005217 (2015).
-
(2015)
PLoS Pathog
, pp. e1005217
-
-
Saravia, J.1
-
30
-
-
1642566675
-
Ontogeny of gamma delta T cells in humans
-
De Rosa, S. C. et al. Ontogeny of gamma delta T cells in humans. J. Immunol. 172, 1637-1645 (2004).
-
(2004)
J. Immunol.
, vol.172
, pp. 1637-1645
-
-
De Rosa, S.C.1
-
31
-
-
84918776802
-
Ontogeny of innate T lymphocytes - Some innate lymphocytes are more innate than others
-
Vermijlen, D. & Prinz, I. Ontogeny of innate T lymphocytes - some innate lymphocytes are more innate than others. Front. Immunol. 5, 486 (2014).
-
(2014)
Front. Immunol.
, vol.5
, pp. 486
-
-
Vermijlen, D.1
Prinz, I.2
-
32
-
-
84901256503
-
Acquisition of innate-like microbial reactivity in mucosal tissues during human fetal MAIT-cell development
-
Leeansyah, E., Loh, L., Nixon, D. F. & Sandberg, J. K. Acquisition of innate-like microbial reactivity in mucosal tissues during human fetal MAIT-cell development. Nat. Commun. 5, 3143 (2014).
-
(2014)
Nat. Commun.
, vol.5
, pp. 3143
-
-
Leeansyah, E.1
Loh, L.2
Nixon, D.F.3
Sandberg, J.K.4
-
33
-
-
78651509914
-
Human B1 cells in umbilical cord and adult peripheral blood express the novel phenotype CD20+ CD27+ CD43+ CD70
-
Griffin, D. O., Holodick, N. E. & Rothstein, T. L. Human B1 cells in umbilical cord and adult peripheral blood express the novel phenotype CD20+ CD27+ CD43+ CD70-. J. Exp. Med. 208, 67-80 (2011).
-
(2011)
J. Exp. Med.
, vol.208
, pp. 67-80
-
-
Griffin, D.O.1
Holodick, N.E.2
Rothstein, T.L.3
-
34
-
-
67049163008
-
Human marginal zone B cells
-
Weill, J.-C., Weller, S. & Reynaud, C.-A. Human marginal zone B cells. Ann. Rev. Immunol. 27, 267-285 (2009).
-
(2009)
Ann. Rev. Immunol.
, vol.27
, pp. 267-285
-
-
Weill, J.-C.1
Weller, S.2
Reynaud, C.-A.3
-
35
-
-
84925441813
-
Control of adaptive immunity by the innate immune system
-
Iwasaki, A. & Medzhitov, R. Control of adaptive immunity by the innate immune system. Nat. Immunol. 16, 343-353 (2015).
-
(2015)
Nat. Immunol.
, vol.16
, pp. 343-353
-
-
Iwasaki, A.1
Medzhitov, R.2
-
36
-
-
84869228450
-
Innate immune function by Toll-like receptors: Distinct responses in newborns and the elderly
-
Kollmann, T. R., Levy, O., Montgomery, R. R. & Goriely, S. Innate immune function by Toll-like receptors: distinct responses in newborns and the elderly. Immunity 37, 771-783 (2012).
-
(2012)
Immunity
, vol.37
, pp. 771-783
-
-
Kollmann, T.R.1
Levy, O.2
Montgomery, R.R.3
Goriely, S.4
-
37
-
-
0036893360
-
Development of interleukin-12-producing capacity throughout childhood
-
Upham, J. W. et al. Development of interleukin-12-producing capacity throughout childhood. Infect. Immun. 70, 6583-6588 (2002).
-
(2002)
Infect. Immun.
, vol.70
, pp. 6583-6588
-
-
Upham, J.W.1
-
38
-
-
1842732225
-
A defect in nucleosome remodeling prevents IL-12(p35) gene transcription in neonatal dendritic cells
-
Goriely, S. et al. A defect in nucleosome remodeling prevents IL-12(p35) gene transcription in neonatal dendritic cells. J. Exp. Med. 199, 1011-1016 (2004).
-
(2004)
J. Exp. Med.
, vol.199
, pp. 1011-1016
-
-
Goriely, S.1
-
39
-
-
33947606977
-
Interferon regulatory factor 3-dependent responses to lipopolysaccharide are selectively blunted in cord blood cells
-
Aksoy, E. et al. Interferon regulatory factor 3-dependent responses to lipopolysaccharide are selectively blunted in cord blood cells. Blood 109, 2887-2893 (2007).
-
(2007)
Blood
, vol.109
, pp. 2887-2893
-
-
Aksoy, E.1
-
40
-
-
73349130456
-
Neonatal innate TLR-mediated responses are distinct from those of adults
-
Kollmann, T. R. et al. Neonatal innate TLR-mediated responses are distinct from those of adults. J. Immunol. 183, 7150-7160 (2009).
-
(2009)
J. Immunol.
, vol.183
, pp. 7150-7160
-
-
Kollmann, T.R.1
-
41
-
-
70350536363
-
IL-12 and type i IFN response of neonatal myeloid DC to human CMV infection
-
Renneson, J. et al. IL-12 and type I IFN response of neonatal myeloid DC to human CMV infection. Eur. J. Immunol. 39, 2789-2799 (2009).
-
(2009)
Eur. J. Immunol.
, vol.39
, pp. 2789-2799
-
-
Renneson, J.1
-
42
-
-
70349777300
-
Skewed pattern of Toll-like receptor 4-mediated cytokine production in human neonatal blood: Low LPS-induced IL-12p70 and high IL-10 persist throughout the first month of life
-
Belderbos, M. E. et al. Skewed pattern of Toll-like receptor 4-mediated cytokine production in human neonatal blood: low LPS-induced IL-12p70 and high IL-10 persist throughout the first month of life. Clin. Immunol. 133, 228-237 (2009).
-
(2009)
Clin. Immunol.
, vol.133
, pp. 228-237
-
-
Belderbos, M.E.1
-
43
-
-
73449084451
-
Monocyte-derived interleukin-10 depresses the Bordetella pertussis-specific gamma interferon response in vaccinated infants
-
Dirix, V. et al. Monocyte-derived interleukin-10 depresses the Bordetella pertussis-specific gamma interferon response in vaccinated infants. Clin. Vaccine Immunol. 16, 1816-1821 (2009).
-
(2009)
Clin. Vaccine Immunol.
, vol.16
, pp. 1816-1821
-
-
Dirix, V.1
-
44
-
-
84862900303
-
Imidazoquinoline Toll-like receptor 8 agonists activate human newborn monocytes and dendritic cells through adenosine-refractory and caspase-1-dependent pathways
-
Philbin, V. J. et al. Imidazoquinoline Toll-like receptor 8 agonists activate human newborn monocytes and dendritic cells through adenosine-refractory and caspase-1-dependent pathways. J. Allergy Clin. Immunol. 130, 195-204.e9 (2012).
-
(2012)
J. Allergy Clin. Immunol.
, vol.130
, pp. 195e9-195e9
-
-
Philbin, V.J.1
-
45
-
-
77958105934
-
MIR-146a mediates protective innate immune tolerance in the neonate intestine
-
Chassin, C. et al. miR-146a mediates protective innate immune tolerance in the neonate intestine. Cell Host Microbe 8, 358-368 (2010).
-
(2010)
Cell Host Microbe
, vol.8
, pp. 358-368
-
-
Chassin, C.1
-
46
-
-
33645843063
-
Postnatal acquisition of endotoxin tolerance in intestinal epithelial cells
-
Lotz, M. et al. Postnatal acquisition of endotoxin tolerance in intestinal epithelial cells. J. Exp. Med. 203, 973-984 (2006).
-
(2006)
J. Exp. Med.
, vol.203
, pp. 973-984
-
-
Lotz, M.1
-
47
-
-
15544362414
-
Mobilization of plasmacytoid and myeloid dendritic cells to mucosal sites in children with respiratory syncytial virus and other viral respiratory infections
-
Gill, M. A. et al. Mobilization of plasmacytoid and myeloid dendritic cells to mucosal sites in children with respiratory syncytial virus and other viral respiratory infections. J. Infect. Dis. 191, 1105-1115 (2005).
-
(2005)
J. Infect. Dis.
, vol.191
, pp. 1105-1115
-
-
Gill, M.A.1
-
48
-
-
1642581673
-
Blood plasmacytoid dendritic cell responses to CpG oligodeoxynucleotides are impaired in human newborns
-
De Wit, D. et al. Blood plasmacytoid dendritic cell responses to CpG oligodeoxynucleotides are impaired in human newborns. Blood 103, 1030-1032 (2004).
-
(2004)
Blood
, vol.103
, pp. 1030-1032
-
-
De Wit, D.1
-
49
-
-
42249109065
-
Interferon regulatory factor 7-mediated responses are defective in cord blood plasmacytoid dendritic cells
-
Danis, B. et al. Interferon regulatory factor 7-mediated responses are defective in cord blood plasmacytoid dendritic cells. Eur. J. Immunol. 38, 507-517 (2008).
-
(2008)
Eur. J. Immunol.
, vol.38
, pp. 507-517
-
-
Danis, B.1
-
50
-
-
84893365419
-
Attenuation of respiratory syncytial virus-induced and RIG-I-dependent type i IFN responses in human neonates and very young children
-
Marr, N. et al. Attenuation of respiratory syncytial virus-induced and RIG-I-dependent type I IFN responses in human neonates and very young children. J. Immunol. 192, 948-957 (2014).
-
(2014)
J. Immunol.
, vol.192
, pp. 948-957
-
-
Marr, N.1
-
51
-
-
85013935391
-
Respiratory syncitial virus infects regulatory B cells in human neonates via chemokine receptor CX3CR1 and promotes lung disease severity
-
Zhivaki, D. et al. Respiratory syncitial virus infects regulatory B cells in human neonates via chemokine receptor CX3CR1 and promotes lung disease severity. Immunity 46, 301-314 (2017).
-
(2017)
Immunity
, vol.46
, pp. 301-314
-
-
Zhivaki, D.1
-
52
-
-
84872222127
-
Neonatal plasmacytoid dendritic cells (pDCs) display subset variation but can elicit potent anti-viral innate responses
-
Zhang, X. et al. Neonatal plasmacytoid dendritic cells (pDCs) display subset variation but can elicit potent anti-viral innate responses. PLoS ONE 8, e52003 (2013).
-
(2013)
PLoS ONE
, vol.8
, pp. e52003
-
-
Zhang, X.1
-
53
-
-
84902791418
-
Plasmacytoid dendritic cells engagement by influenza vaccine as a surrogate strategy for driving T-helper type 1 responses in human neonatal settings
-
Zhang, X. et al. Plasmacytoid dendritic cells engagement by influenza vaccine as a surrogate strategy for driving T-helper type 1 responses in human neonatal settings. J. Infect. Dis. 210, 424-434 (2014).
-
(2014)
J. Infect. Dis.
, vol.210
, pp. 424-434
-
-
Zhang, X.1
-
54
-
-
84962886214
-
Flt3 ligand improves the innate response to respiratory syncytial virus and limits lung disease upon RSV reexposure in neonate mice
-
Remot, A. et al. Flt3 ligand improves the innate response to respiratory syncytial virus and limits lung disease upon RSV reexposure in neonate mice. Eur. J. Immunol. 46, 874-884 (2016).
-
(2016)
Eur. J. Immunol.
, vol.46
, pp. 874-884
-
-
Remot, A.1
-
55
-
-
0037416137
-
Flt3 ligand-treated neonatal mice have increased innate immunity against intracellular pathogens and efficiently control virus infections
-
Vollstedt, S. et al. Flt3 ligand-treated neonatal mice have increased innate immunity against intracellular pathogens and efficiently control virus infections. J. Exp. Med. 197, 575-584 (2003).
-
(2003)
J. Exp. Med.
, vol.197
, pp. 575-584
-
-
Vollstedt, S.1
-
56
-
-
3442877562
-
Treatment of neonatal mice with Flt3 ligand leads to changes in dendritic cell subpopulations associated with enhanced IL-12 and IFN-alpha production
-
Vollstedt, S. et al. Treatment of neonatal mice with Flt3 ligand leads to changes in dendritic cell subpopulations associated with enhanced IL-12 and IFN-alpha production. Eur. J. Immunol. 34, 1849-1860 (2004).
-
(2004)
Eur. J. Immunol.
, vol.34
, pp. 1849-1860
-
-
Vollstedt, S.1
-
57
-
-
0037480902
-
Ontogeny and innate properties of neonatal dendritic cells
-
Sun, C.-M., Fiette, L., Tanguy, M., Leclerc, C. & Lo-Man, R. Ontogeny and innate properties of neonatal dendritic cells. Blood 102, 585-591 (2003).
-
(2003)
Blood
, vol.102
, pp. 585-591
-
-
Sun, C.-M.1
Fiette, L.2
Tanguy, M.3
Leclerc, C.4
Lo-Man, R.5
-
58
-
-
0036498917
-
Efficient in vivo priming of specific cytotoxic T cell responses by neonatal dendritic cells
-
Dadaglio, G., Sun, C. M., Lo-Man, R., Siegrist, C. A. & Leclerc, C. Efficient in vivo priming of specific cytotoxic T cell responses by neonatal dendritic cells. J. Immunol. 168, 2219-2224 (2002).
-
(2002)
J. Immunol.
, vol.168
, pp. 2219-2224
-
-
Dadaglio, G.1
Sun, C.M.2
Lo-Man, R.3
Siegrist, C.A.4
Leclerc, C.5
-
59
-
-
85004097249
-
CD8+ T cells from human neonates are biased toward an innate immune response
-
Galindo-Albarran, A. O. et al. CD8+ T cells from human neonates are biased toward an innate immune response. Cell Rep. 17, 2151-2160 (2016).
-
(2016)
Cell Rep.
, vol.17
, pp. 2151-2160
-
-
Galindo-Albarran, A.O.1
-
60
-
-
2442580881
-
Antiviral CD8 T cells in the control of primary human cytomegalovirus infection in early childhood
-
Chen, S. F. et al. Antiviral CD8 T cells in the control of primary human cytomegalovirus infection in early childhood. J. Infect. Dis. 189, 1619-1627 (2004).
-
(2004)
J. Infect. Dis.
, vol.189
, pp. 1619-1627
-
-
Chen, S.F.1
-
61
-
-
0038481177
-
Mature CD8+ T lymphocyte response to viral infection during fetal life
-
Marchant, A. et al. Mature CD8+ T lymphocyte response to viral infection during fetal life. J. Clin. Invest. 111, 1747-1755 (2003).
-
(2003)
J. Clin. Invest.
, vol.111
, pp. 1747-1755
-
-
Marchant, A.1
-
62
-
-
40549097037
-
CD4+ T cell responses to cytomegalovirus in early life: A prospective birth cohort study
-
Miles, D. J. et al. CD4+ T cell responses to cytomegalovirus in early life: a prospective birth cohort study. J. Infect. Dis. 197, 658-662 (2008).
-
(2008)
J. Infect. Dis.
, vol.197
, pp. 658-662
-
-
Miles, D.J.1
-
63
-
-
77951058003
-
Human cytomegalovirus elicits fetal gammadelta T cell responses in utero
-
Vermijlen, D. et al. Human cytomegalovirus elicits fetal gammadelta T cell responses in utero. J. Exp. Med. 207, 807-821 (2010).
-
(2010)
J. Exp. Med.
, vol.207
, pp. 807-821
-
-
Vermijlen, D.1
-
64
-
-
84925503671
-
Reduced frequencies of polyfunctional CMV-specific T cell responses in infants with congenital CMV infection
-
Gibson, L. et al. Reduced frequencies of polyfunctional CMV-specific T cell responses in infants with congenital CMV infection. J. Clin. Immunol. 35, 289-301 (2015).
-
(2015)
J. Clin. Immunol.
, vol.35
, pp. 289-301
-
-
Gibson, L.1
-
65
-
-
84939239763
-
Functional exhaustion limits CD4+ and CD8+ T-cell responses to congenital cytomegalovirus infection
-
Huygens, A. et al. Functional exhaustion limits CD4+ and CD8+ T-cell responses to congenital cytomegalovirus infection. J. Infect. Dis. 212, 484-494 (2015).
-
(2015)
J. Infect. Dis.
, vol.212
, pp. 484-494
-
-
Huygens, A.1
-
66
-
-
0037105536
-
Human fetuses are able to mount an adultlike CD8 T-cell response
-
Hermann, E. et al. Human fetuses are able to mount an adultlike CD8 T-cell response. Blood 100, 2153-2158 (2002).
-
(2002)
Blood
, vol.100
, pp. 2153-2158
-
-
Hermann, E.1
-
67
-
-
84858999358
-
Uninfected but not unaffected: Chronic maternal infections during pregnancy, fetal immunity, and susceptibility to postnatal infections
-
Dauby, N., Goetghebuer, T., Kollmann, T. R., Levy, J. & Marchant, A. Uninfected but not unaffected: chronic maternal infections during pregnancy, fetal immunity, and susceptibility to postnatal infections. Lancet Infect. Dis. 12, 330-340 (2012).
-
(2012)
Lancet Infect. Dis.
, vol.12
, pp. 330-340
-
-
Dauby, N.1
Goetghebuer, T.2
Kollmann, T.R.3
Levy, J.4
Marchant, A.5
-
68
-
-
84902778138
-
CD4 T cells with effector memory phenotype and function develop in the sterile environment of the fetus
-
Zhang, X. et al. CD4 T cells with effector memory phenotype and function develop in the sterile environment of the fetus. Sci. Transl Med. 6, 238ra72 (2014).
-
(2014)
Sci. Transl Med.
, vol.6
, pp. 238ra72
-
-
Zhang, X.1
-
69
-
-
84872772721
-
Distribution and compartmentalization of human circulating and tissue-resident memory T cell subsets
-
Sathaliyawala, T. et al. Distribution and compartmentalization of human circulating and tissue-resident memory T cell subsets. Immunity 38, 187-197 (2013).
-
(2013)
Immunity
, vol.38
, pp. 187-197
-
-
Sathaliyawala, T.1
-
70
-
-
84865559289
-
Compartmentalized control of skin immunity by resident commensals
-
Naik, S. et al. Compartmentalized control of skin immunity by resident commensals. Science 337, 1115-1119 (2012).
-
(2012)
Science
, vol.337
, pp. 1115-1119
-
-
Naik, S.1
-
71
-
-
84901295133
-
Deconstructing the peptide- MHC specificity of T cell recognition
-
Birnbaum, M. E. et al. Deconstructing the peptide- MHC specificity of T cell recognition. Cell 157, 1073-1087 (2014).
-
(2014)
Cell
, vol.157
, pp. 1073-1087
-
-
Birnbaum, M.E.1
-
72
-
-
84954359892
-
Early-life compartmentalization of human T cell differentiation and regulatory function in mucosal and lymphoid tissues
-
Thome, J. J. et al. Early-life compartmentalization of human T cell differentiation and regulatory function in mucosal and lymphoid tissues. Nat. Med. 22, 72-77 (2016).
-
(2016)
Nat. Med.
, vol.22
, pp. 72-77
-
-
Thome, J.J.1
-
73
-
-
84901280025
-
CD4+ T cells from human neonates and infants are poised spontaneously to run a nonclassical IL-4 program
-
Hebel, K. et al. CD4+ T cells from human neonates and infants are poised spontaneously to run a nonclassical IL-4 program. J. Immunol. 192, 5160-5170 (2014).
-
(2014)
J. Immunol.
, vol.192
, pp. 5160-5170
-
-
Hebel, K.1
-
74
-
-
33847005427
-
The human IL-13 locus in neonatal CD4+ T cells is refractory to the acquisition of a repressive chromatin architecture
-
Webster, R. B., Rodriguez, Y., Klimecki, W. T. & Vercelli, D. The human IL-13 locus in neonatal CD4+ T cells is refractory to the acquisition of a repressive chromatin architecture. J. Biol. Chem. 282, 700-709 (2007).
-
(2007)
J. Biol. Chem.
, vol.282
, pp. 700-709
-
-
Webster, R.B.1
Rodriguez, Y.2
Klimecki, W.T.3
Vercelli, D.4
-
75
-
-
0035858127
-
Neonatal and early life vaccinology
-
Siegrist, C. A. Neonatal and early life vaccinology. Vaccine 19, 3331-3346 (2001).
-
(2001)
Vaccine
, vol.19
, pp. 3331-3346
-
-
Siegrist, C.A.1
-
76
-
-
0033566736
-
Newborns develop a Th1-type immune response to Mycobacterium bovis bacillus Calmette-Guérin vaccination
-
Marchant, A. et al. Newborns develop a Th1-type immune response to Mycobacterium bovis bacillus Calmette-Guérin vaccination. J. Immunol. 163, 2249-2255 (1999).
-
(1999)
J. Immunol.
, vol.163
, pp. 2249-2255
-
-
Marchant, A.1
-
77
-
-
0037080033
-
Influence of Mycobacterium bovis bacillus Calmette-Guerin on antibody and cytokine responses to human neonatal vaccination
-
Ota, M. O. et al. Influence of Mycobacterium bovis bacillus Calmette-Guerin on antibody and cytokine responses to human neonatal vaccination. J. Immunol. 168, 919-925 (2002).
-
(2002)
J. Immunol.
, vol.168
, pp. 919-925
-
-
Ota, M.O.1
-
78
-
-
84981351719
-
Perinatal licensing of thermogenesis by IL-33 and ST2
-
Odegaard, J. I. et al. Perinatal licensing of thermogenesis by IL-33 and ST2. Cell 166, 841-854 (2016).
-
(2016)
Cell
, vol.166
, pp. 841-854
-
-
Odegaard, J.I.1
-
79
-
-
85006802684
-
Perinatal activation of the interleukin-33 pathway promotes type 2 immunity in the developing lung
-
de Kleer, I. M. et al. Perinatal activation of the interleukin-33 pathway promotes type 2 immunity in the developing lung. Immunity 45, 1285-1298 (2016).
-
(2016)
Immunity
, vol.45
, pp. 1285-1298
-
-
De Kleer, I.M.1
-
80
-
-
85026424840
-
The unique immunological and microbial aspects of pregnancy
-
Mor, G., Aldo, P. & Alvero, A. B. The unique immunological and microbial aspects of pregnancy. Nat. Rev. Immunol. http://dx.doi.org/10.1038/nri.2017.64 (2017).
-
(2017)
Nat. Rev. Immunol.
-
-
Mor, G.1
Aldo, P.2
Alvero, A.B.3
-
81
-
-
34248214561
-
Constraints in antigen presentation severely restrict T cell recognition of the allogeneic fetus
-
Erlebacher, A., Vencato, D., Price, K. A., Zhang, D. & Glimcher, L. H. Constraints in antigen presentation severely restrict T cell recognition of the allogeneic fetus. J. Clin. Invest. 117, 1399-1411 (2007).
-
(2007)
J. Clin. Invest.
, vol.117
, pp. 1399-1411
-
-
Erlebacher, A.1
Vencato, D.2
Price, K.A.3
Zhang, D.4
Glimcher, L.H.5
-
82
-
-
84886654997
-
Regulatory T cells and the immune pathogenesis of prenatal infection
-
Rowe, J. H., Ertelt, J. M., Xin, L. & Way, S. S. Regulatory T cells and the immune pathogenesis of prenatal infection. Reproduction 146, R191-R203 (2013).
-
(2013)
Reproduction
, vol.146
, pp. R191-R203
-
-
Rowe, J.H.1
Ertelt, J.M.2
Xin, L.3
Way, S.S.4
-
83
-
-
1542287265
-
Regulatory T cells mediate maternal tolerance to the fetus
-
Aluvihare, V. R., Kallikourdis, M. & Betz, A. G. Regulatory T cells mediate maternal tolerance to the fetus. Nat. Immunol. 5, 266-271 (2004).
-
(2004)
Nat. Immunol.
, vol.5
, pp. 266-271
-
-
Aluvihare, V.R.1
Kallikourdis, M.2
Betz, A.G.3
-
84
-
-
2342603958
-
Normal human pregnancy is associated with an elevation in the immune suppressive CD25+ CD4+ regulatory T-cell subset
-
Somerset, D. A., Zheng, Y., Kilby, M. D., Sansom, D. M. & Drayson, M. T. Normal human pregnancy is associated with an elevation in the immune suppressive CD25+ CD4+ regulatory T-cell subset. Immunology 112, 38-43 (2004).
-
(2004)
Immunology
, vol.112
, pp. 38-43
-
-
Somerset, D.A.1
Zheng, Y.2
Kilby, M.D.3
Sansom, D.M.4
Drayson, M.T.5
-
85
-
-
85017514725
-
Absence of functional fetal regulatory T cells in humans causes in utero organ-specific autoimmunity
-
Allenspach, E. J. et al. Absence of functional fetal regulatory T cells in humans causes in utero organ-specific autoimmunity. J. Allergy Clin. Immunol. http://dx.doi.org/10.1016/j.jaci.2017.02.017 (2017).
-
(2017)
J. Allergy Clin. Immunol.
-
-
Allenspach, E.J.1
-
86
-
-
84889595600
-
Immunosuppressive CD71+ erythroid cells compromise neonatal host defence against infection
-
Elahi, S. et al. Immunosuppressive CD71+ erythroid cells compromise neonatal host defence against infection. Nature 504, 158-162 (2013).
-
(2013)
Nature
, vol.504
, pp. 158-162
-
-
Elahi, S.1
-
87
-
-
84937692768
-
Neonatal CD71+ erythroid cells do not modify murine sepsis mortality
-
Wynn, J. L. et al. Neonatal CD71+ erythroid cells do not modify murine sepsis mortality. J. Immunol. 195, 1064-1070 (2015).
-
(2015)
J. Immunol.
, vol.195
, pp. 1064-1070
-
-
Wynn, J.L.1
-
88
-
-
84884901850
-
Immune suppression by neutrophils and granulocytic myeloid-derived suppressor cells: Similarities and differences
-
Pillay, J., Tak, T., Kamp, V. M. & Koenderman, L. Immune suppression by neutrophils and granulocytic myeloid-derived suppressor cells: similarities and differences. Cell. Mol. Life Sci. 70, 3813-3827 (2013).
-
(2013)
Cell. Mol. Life Sci.
, vol.70
, pp. 3813-3827
-
-
Pillay, J.1
Tak, T.2
Kamp, V.M.3
Koenderman, L.4
-
89
-
-
84907584310
-
Myeloid derived suppressor cells are present at high frequency in neonates and suppress in vitro T cell responses
-
Gervassi, A. et al. Myeloid derived suppressor cells are present at high frequency in neonates and suppress in vitro T cell responses. PLoS ONE 9, e107816 (2014).
-
(2014)
PLoS ONE
, vol.9
, pp. e107816
-
-
Gervassi, A.1
-
90
-
-
84883643725
-
Neutrophilic myeloid-derived suppressor cells in cord blood modulate innate and adaptive immune responses
-
Rieber, N. et al. Neutrophilic myeloid-derived suppressor cells in cord blood modulate innate and adaptive immune responses. Clin. Exp. Immunol. 174, 45-52 (2013).
-
(2013)
Clin. Exp. Immunol.
, vol.174
, pp. 45-52
-
-
Rieber, N.1
-
91
-
-
70449502228
-
Coactivation of Syk kinase and MyD88 adaptor protein pathways by bacteria promotes regulatory properties of neutrophils
-
Zhang, X., Majlessi, L., Deriaud, E., Leclerc, C. & Lo-Man, R. Coactivation of Syk kinase and MyD88 adaptor protein pathways by bacteria promotes regulatory properties of neutrophils. Immunity 31, 761-771 (2009).
-
(2009)
Immunity
, vol.31
, pp. 761-771
-
-
Zhang, X.1
Majlessi, L.2
Deriaud, E.3
Leclerc, C.4
Lo-Man, R.5
-
92
-
-
17444374245
-
Upon TLR9 signaling CD5+ B cells control the IL-12-dependent Th1-priming capacity of neonatal DCs
-
Sun, C. M., Deriaud, E., Leclerc, C. & Lo-Man, R. Upon TLR9 signaling CD5+ B cells control the IL-12-dependent Th1-priming capacity of neonatal DCs. Immunity 22, 467-477 (2005).
-
(2005)
Immunity
, vol.22
, pp. 467-477
-
-
Sun, C.M.1
Deriaud, E.2
Leclerc, C.3
Lo-Man, R.4
-
93
-
-
34249039859
-
Type i interferons protect neonates from acute inflammation through interleukin 10-producing B cells
-
Zhang, X. et al. Type I interferons protect neonates from acute inflammation through interleukin 10-producing B cells. J. Exp. Med. 204, 1107-1118 (2007).
-
(2007)
J. Exp. Med.
, vol.204
, pp. 1107-1118
-
-
Zhang, X.1
-
94
-
-
84859385739
-
Immune regulatory function of B cells
-
Mauri, C. & Bosma, A. Immune regulatory function of B cells. Ann. Rev. Immunol. 30, 221-241 (2012).
-
(2012)
Ann. Rev. Immunol.
, vol.30
, pp. 221-241
-
-
Mauri, C.1
Bosma, A.2
-
95
-
-
84978035560
-
Percentage of peripheral CD19+CD24hiCD38hi regulatory B cells in neonatal sepsis patients and its functional implication
-
Pan, X., Ji, Z. & Xue, J. Percentage of peripheral CD19+CD24hiCD38hi regulatory B cells in neonatal sepsis patients and its functional implication. Med. Sci. Monit. 22, 2374-2378 (2016).
-
(2016)
Med. Sci. Monit.
, vol.22
, pp. 2374-2378
-
-
Pan, X.1
Ji, Z.2
Xue, J.3
-
96
-
-
85017160282
-
IL-10+ regulatory B cells are enriched in cord blood and may protect against cGVHD after cord blood transplantation
-
Sarvaria, A. et al. IL-10+ regulatory B cells are enriched in cord blood and may protect against cGVHD after cord blood transplantation. Blood 128, 1346-1361 (2016).
-
(2016)
Blood
, vol.128
, pp. 1346-1361
-
-
Sarvaria, A.1
-
97
-
-
84891699921
-
Neonatal sepsis: An old problem with new insights
-
Shah, B. A. & Padbury, J. F. Neonatal sepsis: an old problem with new insights. Virulence 5, 170-178 (2014).
-
(2014)
Virulence
, vol.5
, pp. 170-178
-
-
Shah, B.A.1
Padbury, J.F.2
-
98
-
-
0026587349
-
Fetal leukocyte count in rhesus disease
-
Davies, N. P. et al. Fetal leukocyte count in rhesus disease. Arch. Dis. Child. 67, 404-406 (1992).
-
(1992)
Arch. Dis. Child.
, vol.67
, pp. 404-406
-
-
Davies, N.P.1
-
99
-
-
77953206901
-
Neonatal sepsis and neutrophil insufficiencies
-
Melvan, J. N., Bagby, G. J., Welsh, D. A., Nelson, S. & Zhang, P. Neonatal sepsis and neutrophil insufficiencies. Int. Rev. Immunol. 29, 315-348 (2010).
-
(2010)
Int. Rev. Immunol.
, vol.29
, pp. 315-348
-
-
Melvan, J.N.1
Bagby, G.J.2
Welsh, D.A.3
Nelson, S.4
Zhang, P.5
-
100
-
-
0025038572
-
Decreased adherence, chemotaxis and phagocytic activities of neutrophils from preterm neonates
-
Bektas, S., Goetze, B. & Speer, C. Decreased adherence, chemotaxis and phagocytic activities of neutrophils from preterm neonates. Acta Paediatr. 79, 1031-1038 (1990).
-
(1990)
Acta Paediatr.
, vol.79
, pp. 1031-1038
-
-
Bektas, S.1
Goetze, B.2
Speer, C.3
-
101
-
-
84876246089
-
Neutrophil volume, conductivity and scatter in neonatal sepsis
-
Celik, I. H., Demirel, G., Erdeve, O. & Dilmen, U. Neutrophil volume, conductivity and scatter in neonatal sepsis. Pediatr. Infect. Dis. J. 32, 301 (2013).
-
(2013)
Pediatr. Infect. Dis. J.
, vol.32
, pp. 301
-
-
Celik, I.H.1
Demirel, G.2
Erdeve, O.3
Dilmen, U.4
-
102
-
-
67650638848
-
Impaired neutrophil extracellular trap (NET) formation: A novel innate immune deficiency of human neonates
-
Yost, C. C. et al. Impaired neutrophil extracellular trap (NET) formation: a novel innate immune deficiency of human neonates. Blood 113, 6419-6427 (2009).
-
(2009)
Blood
, vol.113
, pp. 6419-6427
-
-
Yost, C.C.1
-
103
-
-
84991632804
-
Neonatal NET-inhibitory factor and related peptides inhibit neutrophil extracellular trap formation
-
Yost, C. C. et al. Neonatal NET-inhibitory factor and related peptides inhibit neutrophil extracellular trap formation. J. Clin. Invest. 126, 3783-3798 (2016).
-
(2016)
J. Clin. Invest.
, vol.126
, pp. 3783-3798
-
-
Yost, C.C.1
-
104
-
-
85026385393
-
The microbiota regulates neutrophil homeostasis and host resistance to Escherichia coli K1 sepsis in neonatal mice
-
Deshmukh, H. S. et al. The microbiota regulates neutrophil homeostasis and host resistance to Escherichia coli K1 sepsis in neonatal mice. Nat. Med. 20, 528-534 (2014).
-
(2014)
Nat. Med.
, vol.20
, pp. 528-534
-
-
Deshmukh, H.S.1
-
105
-
-
84885983093
-
TLR2-induced IL-10 production impairs neutrophil recruitment to infected tissues during neonatal bacterial sepsis
-
Andrade, E. B. et al. TLR2-induced IL-10 production impairs neutrophil recruitment to infected tissues during neonatal bacterial sepsis. J. Immunol. 191, 4759-4768 (2013).
-
(2013)
J. Immunol.
, vol.191
, pp. 4759-4768
-
-
Andrade, E.B.1
-
106
-
-
84921064072
-
Impaired NLRP3 inflammasome activity during fetal development regulates IL-1 β production in human monocytes
-
Sharma, A. A. et al. Impaired NLRP3 inflammasome activity during fetal development regulates IL-1 β production in human monocytes. Eur. J. Immunol. 45, 238-249 (2015).
-
(2015)
Eur. J. Immunol.
, vol.45
, pp. 238-249
-
-
Sharma, A.A.1
-
107
-
-
84946064371
-
Attenuated innate immune defenses in very premature neonates during the neonatal period
-
Marchant, E. A. et al. Attenuated innate immune defenses in very premature neonates during the neonatal period. Pediatr. Res. 78, 492-497 (2015).
-
(2015)
Pediatr. Res.
, vol.78
, pp. 492-497
-
-
Marchant, E.A.1
-
108
-
-
84897538320
-
Distinct functional programming of human fetal and adult monocytes
-
Krow-Lucal, E. R., Kim, C. C., Burt, T. D. & McCune, J. M. Distinct functional programming of human fetal and adult monocytes. Blood 123, 1897-1904 (2014).
-
(2014)
Blood
, vol.123
, pp. 1897-1904
-
-
Krow-Lucal, E.R.1
Kim, C.C.2
Burt, T.D.3
McCune, J.M.4
-
109
-
-
84880500884
-
Reduced Frequency of a CD14+ CD16+ monocyte subset with high Toll-like receptor 4 expression in cord blood compared to adult blood contributes to lipopolysaccharide hyporesponsiveness in newborns
-
Pedraza-Sanchez, S., Hise, A. G., Ramachandra, L., Arechavaleta-Velasco, F. & King, C. L. Reduced Frequency of a CD14+ CD16+ monocyte subset with high Toll-like receptor 4 expression in cord blood compared to adult blood contributes to lipopolysaccharide hyporesponsiveness in newborns. Clin. Vaccine Immunol. 20, 962-971 (2013).
-
(2013)
Clin. Vaccine Immunol.
, vol.20
, pp. 962-971
-
-
Pedraza-Sanchez, S.1
Hise, A.G.2
Ramachandra, L.3
Arechavaleta-Velasco, F.4
King, C.L.5
-
110
-
-
84940056692
-
Age-related gene expression differences in monocytes from human neonates, young adults, and older adults
-
Lissner, M. M. et al. Age-related gene expression differences in monocytes from human neonates, young adults, and older adults. PLoS ONE 10, e0132061 (2015).
-
(2015)
PLoS ONE
, vol.10
, pp. e0132061
-
-
Lissner, M.M.1
-
111
-
-
33746214770
-
The adenosine system selectively inhibits TLR-mediated TNF-α production in the human newborn
-
Levy, O. et al. The adenosine system selectively inhibits TLR-mediated TNF-α production in the human newborn. J. Immunol. 177, 1956-1966 (2006).
-
(2006)
J. Immunol.
, vol.177
, pp. 1956-1966
-
-
Levy, O.1
-
112
-
-
85018332809
-
S100-alarmin-induced innate immune programming protects newborn infants from sepsis
-
Ulas, T. et al. S100-alarmin-induced innate immune programming protects newborn infants from sepsis. Nat. Immunol. http://dx.doi.org/10.1038/ni.3745 (2017).
-
(2017)
Nat. Immunol.
-
-
Ulas, T.1
-
113
-
-
84959450073
-
High expression levels of macrophage migration inhibitory factor sustain the innate immune responses of neonates
-
Roger, T. et al. High expression levels of macrophage migration inhibitory factor sustain the innate immune responses of neonates. Proc. Natl Acad. Sci. USA 113, E997-E1005 (2016).
-
(2016)
Proc. Natl Acad. Sci. USA
, vol.113
, pp. E997-E1005
-
-
Roger, T.1
-
114
-
-
84859389494
-
Immune status in very preterm neonates
-
Azizia, M., Lloyd, J., Allen, M., Klein, N. & Peebles, D. Immune status in very preterm neonates. Pediatrics 129, E967-E974 (2012).
-
(2012)
Pediatrics
, vol.129
, pp. E967-E974
-
-
Azizia, M.1
Lloyd, J.2
Allen, M.3
Klein, N.4
Peebles, D.5
-
115
-
-
76849090410
-
Monocyte HLA-DR expression as predictor of poor outcome in neonates with late onset neonatal sepsis
-
Genel, F., Atlihan, F., Ozsu, E. & Ozbek, E. Monocyte HLA-DR expression as predictor of poor outcome in neonates with late onset neonatal sepsis. J. Infect. 60, 224-228 (2010).
-
(2010)
J. Infect.
, vol.60
, pp. 224-228
-
-
Genel, F.1
Atlihan, F.2
Ozsu, E.3
Ozbek, E.4
-
116
-
-
78649565977
-
Profound lack of interleukin (IL)-12/IL-23p40 in neonates born early in gestation is associated with an increased risk of sepsis
-
Lavoie, P. M. et al. Profound lack of interleukin (IL)-12/IL-23p40 in neonates born early in gestation is associated with an increased risk of sepsis. J. Infect. Dis. 202, 1754-1763 (2010).
-
(2010)
J. Infect. Dis.
, vol.202
, pp. 1754-1763
-
-
Lavoie, P.M.1
-
117
-
-
84921957499
-
Interleukin-8 (CXCL8) production is a signatory T cell effector function of human newborn infants
-
Gibbons, D. et al. Interleukin-8 (CXCL8) production is a signatory T cell effector function of human newborn infants. Nat. Med. 20, 1206-1210 (2014).
-
(2014)
Nat. Med.
, vol.20
, pp. 1206-1210
-
-
Gibbons, D.1
-
118
-
-
0346688578
-
Multiple leucocyte activation markers to detect neonatal infection
-
Hodge, G., Hodge, S., Han, P. & Haslam, R. Multiple leucocyte activation markers to detect neonatal infection. Clin. Exp. Immunol. 135, 125-129 (2004).
-
(2004)
Clin. Exp. Immunol.
, vol.135
, pp. 125-129
-
-
Hodge, G.1
Hodge, S.2
Han, P.3
Haslam, R.4
-
119
-
-
84978924849
-
Regulatory T cell frequencies are increased in preterm infants with clinical early-onset sepsis
-
Pagel, J. et al. Regulatory T cell frequencies are increased in preterm infants with clinical early-onset sepsis. Clin. Exp. Immunol. 185, 219-227 (2016).
-
(2016)
Clin. Exp. Immunol.
, vol.185
, pp. 219-227
-
-
Pagel, J.1
-
120
-
-
85026388023
-
Early life factors that affect allergy development
-
Reynolds, L. A. & Finlay, B. B. Early life factors that affect allergy development. Nat. Rev. Immunol. http://dx.doi.org/10.1038/nri.2017.39 (2017).
-
(2017)
Nat. Rev. Immunol.
-
-
Reynolds, L.A.1
Finlay, B.B.2
-
121
-
-
0034597918
-
Detection of house-dust-mite allergen in amniotic fluid and umbilical-cord blood
-
Holloway, J. A. et al. Detection of house-dust-mite allergen in amniotic fluid and umbilical-cord blood. Lancet 356, 1900-1902 (2000).
-
(2000)
Lancet
, vol.356
, pp. 1900-1902
-
-
Holloway, J.A.1
-
122
-
-
1542315424
-
Maternally delivered nutritive allergens in cord blood and in placental tissue of term and preterm neonates
-
Edelbauer, M. et al. Maternally delivered nutritive allergens in cord blood and in placental tissue of term and preterm neonates. Clin. Exp. Allergy 34, 189-193 (2004).
-
(2004)
Clin. Exp. Allergy
, vol.34
, pp. 189-193
-
-
Edelbauer, M.1
-
123
-
-
0032524991
-
Transplacental priming of the human immune system to environmental allergens: Universal skewing of initial T cell responses toward the Th2 cytokine profile
-
Prescott, S. L. et al. Transplacental priming of the human immune system to environmental allergens: universal skewing of initial T cell responses toward the Th2 cytokine profile. J. Immunol. 160, 4730-4737 (1998).
-
(1998)
J. Immunol.
, vol.160
, pp. 4730-4737
-
-
Prescott, S.L.1
-
124
-
-
0033573788
-
Development of allergen-specific T-cell memory in atopic and normal children
-
Prescott, S. L. et al. Development of allergen-specific T-cell memory in atopic and normal children. Lancet 353, 196-200 (1999).
-
(1999)
Lancet
, vol.353
, pp. 196-200
-
-
Prescott, S.L.1
-
125
-
-
84992362202
-
Fetal phagocytes take up allergens to initiate T-helper cell type 2 immunity and facilitate allergic airway responses
-
Chen, J. C. et al. Fetal phagocytes take up allergens to initiate T-helper cell type 2 immunity and facilitate allergic airway responses. Am. J. Respir. Crit. Care Med. 194, 934-947 (2016).
-
(2016)
Am. J. Respir. Crit. Care Med.
, vol.194
, pp. 934-947
-
-
Chen, J.C.1
-
126
-
-
79551476167
-
Differences in innate immune function between allergic and nonallergic children: New insights into immune ontogeny
-
Tulic, M. K. et al. Differences in innate immune function between allergic and nonallergic children: new insights into immune ontogeny. J. Allergy Clin. Immunol. 127, 470-478 (2011).
-
(2011)
J. Allergy Clin. Immunol.
, vol.127
, pp. 470-478
-
-
Tulic, M.K.1
-
127
-
-
84954270866
-
Cord blood monocyte-derived inflammatory cytokines suppress IL-2 and induce nonclassic "tH2-type" immunity associated with development of food allergy
-
Zhang, Y. et al. Cord blood monocyte-derived inflammatory cytokines suppress IL-2 and induce nonclassic "TH2-type" immunity associated with development of food allergy. Sci. Transl Med. 8, 321ra8 (2016).
-
(2016)
Sci. Transl Med.
, vol.8
, pp. 321ra8
-
-
Zhang, Y.1
-
128
-
-
0141729471
-
Type 1 and type 2 cytokine imbalance in acute respiratory syncytial virus bronchiolitis
-
Legg, J. P., Hussain, I. R., Warner, J. A., Johnston, S. L. & Warner, J. O. Type 1 and type 2 cytokine imbalance in acute respiratory syncytial virus bronchiolitis. Am. J. Respir. Crit. Care 168, 633-639 (2003).
-
(2003)
Am. J. Respir. Crit. Care
, vol.168
, pp. 633-639
-
-
Legg, J.P.1
Hussain, I.R.2
Warner, J.A.3
Johnston, S.L.4
Warner, J.O.5
-
129
-
-
25844470281
-
Respiratory syncytial virus and other respiratory viruses during the first 3 months of life promote a local TH2-like response
-
Kristjansson, S. et al. Respiratory syncytial virus and other respiratory viruses during the first 3 months of life promote a local TH2-like response. J. Allergy Clin. Immun. 116, 805-811 (2005).
-
(2005)
J. Allergy Clin. Immun.
, vol.116
, pp. 805-811
-
-
Kristjansson, S.1
-
130
-
-
78649425313
-
Transforming growth factor beta is a major regulator of human neonatal immune responses following respiratory syncytial virus infection
-
Thornburg, N. J., Shepherd, B. & Crowe, J. E. Transforming growth factor beta is a major regulator of human neonatal immune responses following respiratory syncytial virus infection. J. Virol. 84, 12895-12902 (2010).
-
(2010)
J. Virol.
, vol.84
, pp. 12895-12902
-
-
Thornburg, N.J.1
Shepherd, B.2
Crowe, J.E.3
-
131
-
-
44649134534
-
Children with egg allergy have evidence of reduced neonatal CD4+CD25+CD127lo/- regulatory T cell function
-
Smith, M. et al. Children with egg allergy have evidence of reduced neonatal CD4+CD25+CD127lo/- regulatory T cell function. J. Allergy Clin. Immunol. 121, 1460-1466 (2008).
-
(2008)
J. Allergy Clin. Immunol.
, vol.121
, pp. 1460-1466
-
-
Smith, M.1
-
132
-
-
44649151107
-
Impairment of T-regulatory cells in cord blood of atopic mothers
-
Schaub, B. et al. Impairment of T-regulatory cells in cord blood of atopic mothers. J. Allergy Clin. Immunol. 121, 1491-1499 (2008).
-
(2008)
J. Allergy Clin. Immunol.
, vol.121
, pp. 1491-1499
-
-
Schaub, B.1
-
133
-
-
78649512314
-
Farm living: Effects on childhood asthma and allergy
-
von Mutius, E. & Vercelli, D. Farm living: effects on childhood asthma and allergy. Nat. Rev. Immunol. 10, 861-868 (2010).
-
(2010)
Nat. Rev. Immunol.
, vol.10
, pp. 861-868
-
-
Von Mutius, E.1
Vercelli, D.2
-
134
-
-
63649143905
-
Maternal farm exposure modulates neonatal immune mechanisms through regulatory T cells
-
Schaub, B. et al. Maternal farm exposure modulates neonatal immune mechanisms through regulatory T cells. J. Allergy Clin. Immunol. 123, 774-782.e5 (2009).
-
(2009)
J. Allergy Clin. Immunol.
, vol.123
, pp. 774e5-782e5
-
-
Schaub, B.1
-
136
-
-
84954306995
-
Immune- microbiota interactions: Dysbiosis as a global health issue
-
Logan, A. C., Jacka, F. N. & Prescott, S. L. Immune- microbiota interactions: dysbiosis as a global health issue. Curr. Allergy Asthma Rep. 16, 13 (2016).
-
(2016)
Curr. Allergy Asthma Rep.
, vol.16
, pp. 13
-
-
Logan, A.C.1
Jacka, F.N.2
Prescott, S.L.3
-
137
-
-
84887960425
-
Intestinal microbial diversity during early-life colonization shapes long-term IgE levels
-
Cahenzli, J., Koller, Y., Wyss, M., Geuking, M. B. & McCoy, K. D. Intestinal microbial diversity during early-life colonization shapes long-term IgE levels. Cell Host Microbe 14, 559-570 (2013).
-
(2013)
Cell Host Microbe
, vol.14
, pp. 559-570
-
-
Cahenzli, J.1
Koller, Y.2
Wyss, M.3
Geuking, M.B.4
McCoy, K.D.5
-
138
-
-
84942874856
-
Early infancy microbial and metabolic alterations affect risk of childhood asthma
-
Arrieta, M. C. et al. Early infancy microbial and metabolic alterations affect risk of childhood asthma. Sci. Transl Med. 7, 307ra152 (2015).
-
(2015)
Sci. Transl Med.
, vol.7
, pp. 307ra152
-
-
Arrieta, M.C.1
-
139
-
-
84987602337
-
Neonatal gut microbiota associates with childhood multisensitized atopy and T cell differentiation
-
Fujimura, K. E. et al. Neonatal gut microbiota associates with childhood multisensitized atopy and T cell differentiation. Nat. Med. 22, 1187-1191 (2016).
-
(2016)
Nat. Med.
, vol.22
, pp. 1187-1191
-
-
Fujimura, K.E.1
-
140
-
-
84881068658
-
The microbial metabolites, short-chain fatty acids, regulate colonic Treg cell homeostasis
-
Smith, P. M. et al. The microbial metabolites, short-chain fatty acids, regulate colonic Treg cell homeostasis. Science 341, 569-573 (2013).
-
(2013)
Science
, vol.341
, pp. 569-573
-
-
Smith, P.M.1
-
141
-
-
84890564250
-
Commensal microbe-derived butyrate induces the differentiation of colonic regulatory T cells
-
Furusawa, Y. et al. Commensal microbe-derived butyrate induces the differentiation of colonic regulatory T cells. Nature 504, 446-450 (2013).
-
(2013)
Nature
, vol.504
, pp. 446-450
-
-
Furusawa, Y.1
-
142
-
-
84890550163
-
Metabolites produced by commensal bacteria promote peripheral regulatory T-cell generation
-
Arpaia, N. et al. Metabolites produced by commensal bacteria promote peripheral regulatory T-cell generation. Nature 504, 451-455 (2013).
-
(2013)
Nature
, vol.504
, pp. 451-455
-
-
Arpaia, N.1
-
143
-
-
84902201196
-
Lung microbiota promotes tolerance to allergens in neonates via PD-L1
-
Gollwitzer, E. S. et al. Lung microbiota promotes tolerance to allergens in neonates via PD-L1. Nat. Med. 20, 642-647 (2014).
-
(2014)
Nat. Med.
, vol.20
, pp. 642-647
-
-
Gollwitzer, E.S.1
-
144
-
-
84875133333
-
Four-year efficacy of RTS,S/AS01E and its interaction with malaria exposure
-
Olotu, A. et al. Four-year efficacy of RTS,S/AS01E and its interaction with malaria exposure. N. Engl. J. Med. 368, 1111-1120 (2013).
-
(2013)
N. Engl. J. Med.
, vol.368
, pp. 1111-1120
-
-
Olotu, A.1
-
145
-
-
84859405717
-
Signaling by myeloid C-type lectin receptors in immunity and homeostasis
-
Sancho, D. & Reis e Sousa, C. Signaling by myeloid C-type lectin receptors in immunity and homeostasis. Ann. Rev. Immunol. 30, 491-529 (2012).
-
(2012)
Ann. Rev. Immunol.
, vol.30
, pp. 491-529
-
-
Sancho, D.1
Reis Sousa, E.C.2
-
146
-
-
66749092107
-
A liposome-based mycobacterial vaccine induces potent adult and neonatal multifunctional T cells through the exquisite targeting of dendritic cells
-
Kamath, A. T. et al. A liposome-based mycobacterial vaccine induces potent adult and neonatal multifunctional T cells through the exquisite targeting of dendritic cells. PLoS ONE 4, e5771 (2009).
-
(2009)
PLoS ONE
, vol.4
, pp. e5771
-
-
Kamath, A.T.1
-
147
-
-
85027929730
-
Dectin-1 activation unlocks IL12A expression and reveals the TH1 potency of neonatal dendritic cells
-
Lemoine, S. et al. Dectin-1 activation unlocks IL12A expression and reveals the TH1 potency of neonatal dendritic cells. J. Allergy Clin. Immunol. 136, 1355-1368.e15 (2015).
-
(2015)
J. Allergy Clin. Immunol.
, vol.136
, pp. 1355e15-1368e15
-
-
Lemoine, S.1
-
148
-
-
84964840369
-
IL-12p40/IL-10 producing preCD8alpha/Clec9A+ dendritic cells are induced in neonates upon Listeria monocytogenes infection
-
Torres, D. et al. IL-12p40/IL-10 producing preCD8alpha/Clec9A+ dendritic cells are induced in neonates upon Listeria monocytogenes infection. PLoS Pathog. 12, e1005561 (2016).
-
(2016)
PLoS Pathog.
, vol.12
, pp. e1005561
-
-
Torres, D.1
-
149
-
-
84994525492
-
Systems biology of immunity to MF59-adjuvanted versus nonadjuvanted trivalent seasonal influenza vaccines in early childhood
-
Nakaya, H. I. et al. Systems biology of immunity to MF59-adjuvanted versus nonadjuvanted trivalent seasonal influenza vaccines in early childhood. Proc. Natl Acad. Sci. USA 113, 1853-1858 (2016).
-
(2016)
Proc. Natl Acad. Sci. USA
, vol.113
, pp. 1853-1858
-
-
Nakaya, H.I.1
-
150
-
-
78650566298
-
Biological challenges and technological opportunities for respiratory syncytial virus vaccine development
-
Graham, B. S. Biological challenges and technological opportunities for respiratory syncytial virus vaccine development. Immunol. Rev. 239, 149-166 (2011).
-
(2011)
Immunol. Rev.
, vol.239
, pp. 149-166
-
-
Graham, B.S.1
-
151
-
-
34249878532
-
Antigen-specific immune responses to influenza vaccine
-
Rastogi, D. et al. Antigen-specific immune responses to influenza vaccine in utero. J. Clin. Invest. 117, 1637-1646 (2007).
-
(2007)
Utero. J. Clin. Invest.
, vol.117
, pp. 1637-1646
-
-
Rastogi, D.1
-
152
-
-
0014493282
-
An epidemiologic study of altered clinical reactivity to respiratory syncytial (RS) virus infection in children previously vaccinated with an inactivated RS virus vaccine
-
Kapikian, A. Z., Mitchell, R. H., Chanock, R. M., Shvedoff, R. A. & Stewart, C. E. An epidemiologic study of altered clinical reactivity to respiratory syncytial (RS) virus infection in children previously vaccinated with an inactivated RS virus vaccine. Am. J. Epidemiol. 89, 405-421 (1969).
-
(1969)
Am. J. Epidemiol.
, vol.89
, pp. 405-421
-
-
Kapikian, A.Z.1
Mitchell, R.H.2
Chanock, R.M.3
Shvedoff, R.A.4
Stewart, C.E.5
|