Role of factor H and related proteins in regulating complement activation in the macula, and relevance to age-related macular degeneration

Journal of Clinical Medicine

Volumn 4, Issue 1, 2014, Pages 18-31

  Clark, Simon J ^a,b   Bishop, Paul N ^a,b,c  

^a UNIVERSITY OF MANCHESTER   (United Kingdom)

^b MANCHESTER UNIVERSITY NHS FOUNDATION TRUST   (United Kingdom)

^c MANCHESTER ROYAL EYE HOSPITAL   (United Kingdom)

Author keywords

Age related macular degeneration; Complement factor H; Factor H; Factor H related proteins; Factor H like protein 1

Indexed keywords

AGENTS ACTING ON THE EYE; ALTERNATIVE COMPLEMENT PATHWAY C3 C5 CONVERTASE; COMPLEMENT COMPONENT C5A; COMPLEMENT CONTROL PROTEIN; COMPLEMENT FACTOR D; COMPLEMENT FACTOR H; ECULIZUMAB; FACTOR H LIKE PROTEIN 1; HEPARAN SULFATE; LAMPALIZUMAB; LFG316; POT 4; UNCLASSIFIED DRUG; ZIMURA;

AGE RELATED MACULAR DEGENERATION; BRUCH MEMBRANE; CHROMOSOME 1; CHROMOSOME 10; COMPLEMENT ACTIVATION; DNA POLYMORPHISM; GENE LOCUS; GENE MUTATION; GENE SEQUENCE; GENETIC VARIABILITY; HUMAN; IMMUNITY; INFLAMMATION; META ANALYSIS (TOPIC); PHASE 1 CLINICAL TRIAL (TOPIC); PHASE 2 CLINICAL TRIAL (TOPIC); PHASE 3 CLINICAL TRIAL (TOPIC); RETINA MACULA LUTEA; REVIEW; SIGNAL TRANSDUCTION; TISSUE INTERACTION;

EID: 85067220142     PISSN: None     EISSN: 20770383     Source Type: Journal    
DOI: 10.3390/jcm4010018     Document Type: Review

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