Dimerization of complement factor H-related proteins modulates complement activation in vivo

Proceedings of the National Academy of Sciences of the United States of America

Volumn 110, Issue 12, 2013, Pages 4685-4690

  Goicoechea De Jorge, Elena ^a   Caesar, Joseph J E ^b   Malik, Talat H ^a   Patel, Mitali ^a   Colledge, Matthew ^b   Johnson, Steven ^b   Hakobyan, Svetlana ^c   Morgan, B Paul ^c   Harris, Claire L ^c   Pickering, Matthew C ^a   Lea, Susan M ^b  

^a IMPERIAL COLLEGE LONDON   (United Kingdom)

^b UNIVERSITY OF OXFORD   (United Kingdom)

^c CARDIFF UNIVERSITY   (United Kingdom)

Author keywords

Deregulation; Innate immunity; Structure

Indexed keywords

COMPLEMENT FACTOR H; COMPLEMENT INHIBITOR; HETERODIMER; HOMODIMER; LIGAND;

ARTICLE; BINDING AFFINITY; COMPLEMENT ACTIVATION; CONTROLLED STUDY; DIMERIZATION; DISEASE PREDISPOSITION; HUMAN; IN VIVO STUDY; PRIORITY JOURNAL; PROTEIN MOTIF; PROTEIN STRUCTURE; STRUCTURE ANALYSIS;

AMINO ACID MOTIFS; COMPLEMENT ACTIVATION; COMPLEMENT SYSTEM PROTEINS; DIMERIZATION; GENETIC LOCI; HUMANS; PROTEIN STRUCTURE, QUATERNARY; PROTEIN STRUCTURE, TERTIARY; STRUCTURE COLLAPSE;

EID: 84875239064     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1219260110     Document Type: Article

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