Tissue-specific host recognition by complement factor H is mediated by differential activities of its glycosaminoglycan-binding regions

Journal of Immunology

Volumn 190, Issue 5, 2013, Pages 2049-2057

  Clark, Simon J ^a,b,c   Ridge, Liam A ^a   Herbert, Andrew P ^d   Hakobyan, Svetlana ^e   Mulloy, Barbara ^f   Lennon, Rachel ^a   Würzner, Reinhard ^g   Morgan, B Paul ^e   Uhrín, Dusan ^d   Bishop, Paul N ^b,c   Day, Anthony J ^a  

^a UNIVERSITY OF MANCHESTER   (United Kingdom)

^b UNIVERSITY OF MANCHESTER   (United Kingdom)

^c MANCHESTER UNIVERSITY NHS FOUNDATION TRUST   (United Kingdom)

^d UNIVERSITY OF EDINBURGH   (United Kingdom)

^e CARDIFF UNIVERSITY   (United Kingdom)

^f NATIONAL INSTITUTE FOR BIOLOGICAL STANDARDS AND CONTROL   (United Kingdom)

^g INNSBRUCK MEDICAL UNIVERSITY   (Austria)

Author keywords

[No Author keywords available]

Indexed keywords

COMPLEMENT FACTOR H; GLYCOSAMINOGLYCAN; HEPARIN;

ADULT; AFFINITY CHROMATOGRAPHY; AGED; ANTIGEN RECOGNITION; ARTICLE; BINDING SITE; BIOTINYLATION; CONTROLLED STUDY; FEMALE; FLUORESCENCE; GLOMERULUS; HEMOLYTIC UREMIC SYNDROME; HUMAN; HUMAN TISSUE; KIDNEY PARENCHYMA; MALE; PRIORITY JOURNAL; PROTEIN BINDING; RETINA MACULA AGE RELATED DEGENERATION; RETINA MACULA LUTEA;

ADULT; AGED; AGED, 80 AND OVER; AMINO ACID SUBSTITUTION; AUTOPSY; BINDING SITES; COMPLEMENT ACTIVATION; COMPLEMENT FACTOR H; ESCHERICHIA COLI; EYE; FEMALE; HEMOLYTIC-UREMIC SYNDROME; HEPARITIN SULFATE; HUMANS; KIDNEY; MACULAR DEGENERATION; MALE; MIDDLE AGED; MUTATION; ORGAN SPECIFICITY; PROTEIN BINDING; RECOMBINANT PROTEINS;

EID: 84874253499     PISSN: 00221767     EISSN: 15506606     Source Type: Journal    
DOI: 10.4049/jimmunol.1201751     Document Type: Article

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