-
1
-
-
0037025356
-
AMP-activated protein kinase suppresses protein synthesis in rat skeletal muscle through down-regulated mammalian target of rapamycin (mTOR) signaling
-
Bolster D.R., Crozier S.J., Kimball S.R., Jefferson L.S. AMP-activated protein kinase suppresses protein synthesis in rat skeletal muscle through down-regulated mammalian target of rapamycin (mTOR) signaling. J. Biol. Chem 2002, 277:23977-23980.
-
(2002)
J. Biol. Chem
, vol.277
, pp. 23977-23980
-
-
Bolster, D.R.1
Crozier, S.J.2
Kimball, S.R.3
Jefferson, L.S.4
-
2
-
-
18544375186
-
RAGE is a multiligand receptor of the immunoglobulin superfamily: implications for homeostasis and chronic disease
-
Bucciarelli L.G., Wendt T., Rong L., Lalla E., Hofmann M.A., Goova M.T., Taguchi A., Yan S.F., Yan S.D., Stern D.M., Schmidt A.M. RAGE is a multiligand receptor of the immunoglobulin superfamily: implications for homeostasis and chronic disease. Cell. Mol. Life Sci 2002, 59:1117-1128.
-
(2002)
Cell. Mol. Life Sci
, vol.59
, pp. 1117-1128
-
-
Bucciarelli, L.G.1
Wendt, T.2
Rong, L.3
Lalla, E.4
Hofmann, M.A.5
Goova, M.T.6
Taguchi, A.7
Yan, S.F.8
Yan, S.D.9
Stern, D.M.10
Schmidt, A.M.11
-
3
-
-
0347318052
-
The AMP-activated protein kinase cascade-a unifying system for energy control
-
Carling D. The AMP-activated protein kinase cascade-a unifying system for energy control. Trends Biochem. Sci 2004, 29:18-24.
-
(2004)
Trends Biochem. Sci
, vol.29
, pp. 18-24
-
-
Carling, D.1
-
4
-
-
40549129366
-
Disrupted intracellular calcium regulates BACE1 gene expression via nuclear factor of activated T cells 1 (NFAT 1) signaling
-
Cho H.J., Jin S.M., Youn H.D., Huh K., Mook-Jung I. Disrupted intracellular calcium regulates BACE1 gene expression via nuclear factor of activated T cells 1 (NFAT 1) signaling. Aging Cell 2008, 7:137-147.
-
(2008)
Aging Cell
, vol.7
, pp. 137-147
-
-
Cho, H.J.1
Jin, S.M.2
Youn, H.D.3
Huh, K.4
Mook-Jung, I.5
-
5
-
-
68849129707
-
RAGE regulates BACE1 and Abeta generation via NFAT1 activation in Alzheimer's disease animal model
-
Cho H.J., Son S.M., Jin S.M., Hong H.S., Shin D.H., Kim S.J., Huh K., Mook-Jung I. RAGE regulates BACE1 and Abeta generation via NFAT1 activation in Alzheimer's disease animal model. FASEB J 2009, 23:2639-2649.
-
(2009)
FASEB J
, vol.23
, pp. 2639-2649
-
-
Cho, H.J.1
Son, S.M.2
Jin, S.M.3
Hong, H.S.4
Shin, D.H.5
Kim, S.J.6
Huh, K.7
Mook-Jung, I.8
-
6
-
-
0035860237
-
The regulation of AMP-activated protein kinase by H(2)O(2)
-
Choi S.L., Kim S.J., Lee K.T., Kim J., Mu J., Birnbaum M.J., Soo Kim S., Ha J. The regulation of AMP-activated protein kinase by H(2)O(2). Biochem. Biophys. Res. Commun 2001, 287:92-97.
-
(2001)
Biochem. Biophys. Res. Commun
, vol.287
, pp. 92-97
-
-
Choi, S.L.1
Kim, S.J.2
Lee, K.T.3
Kim, J.4
Mu, J.5
Birnbaum, M.J.6
Soo Kim, S.7
Ha, J.8
-
8
-
-
0035921427
-
The discrepancy between presenilin subcellular localization and gamma-secretase processing of amyloid precursor protein
-
Cupers P., Bentahir M., Craessaerts K., Orlans I., Vanderstichele H., Saftig P., De Strooper B., Annaert W. The discrepancy between presenilin subcellular localization and gamma-secretase processing of amyloid precursor protein. J. Cell Biol 2001, 154:731-740.
-
(2001)
J. Cell Biol
, vol.154
, pp. 731-740
-
-
Cupers, P.1
Bentahir, M.2
Craessaerts, K.3
Orlans, I.4
Vanderstichele, H.5
Saftig, P.6
De Strooper, B.7
Annaert, W.8
-
9
-
-
0037703255
-
RAGE mediates amyloid-beta peptide transport across the blood-brain barrier and accumulation in brain
-
Deane R., Du Yan S., Submamaryan R.K., LaRue B., Jovanovic S., Hogg E., Welch D., Manness L., Lin C., Yu J., Zhu H., Ghiso J., Frangione B., Stern A., Schmidt A.M., Armstrong D.L., Arnold B., Liliensiek B., Nawroth P., Hofman F., Kindy M., Stern D., Zlokovic B. RAGE mediates amyloid-beta peptide transport across the blood-brain barrier and accumulation in brain. Nat. Med 2003, 9:907-913.
-
(2003)
Nat. Med
, vol.9
, pp. 907-913
-
-
Deane, R.1
Du Yan, S.2
Submamaryan, R.K.3
LaRue, B.4
Jovanovic, S.5
Hogg, E.6
Welch, D.7
Manness, L.8
Lin, C.9
Yu, J.10
Zhu, H.11
Ghiso, J.12
Frangione, B.13
Stern, A.14
Schmidt, A.M.15
Armstrong, D.L.16
Arnold, B.17
Liliensiek, B.18
Nawroth, P.19
Hofman, F.20
Kindy, M.21
Stern, D.22
Zlokovic, B.23
more..
-
10
-
-
0038664363
-
Reconstitution of gamma-secretase activity
-
Edbauer D., Winkler E., Regula J.T., Pesold B., Steiner H., Haass C. Reconstitution of gamma-secretase activity. Nat. Cell Biol 2003, 5:486-488.
-
(2003)
Nat. Cell Biol
, vol.5
, pp. 486-488
-
-
Edbauer, D.1
Winkler, E.2
Regula, J.T.3
Pesold, B.4
Steiner, H.5
Haass, C.6
-
11
-
-
33644604875
-
Neurodegeneration induces upregulation of Beclin 1
-
Erlich S., Shohami E., Pinkas-Kramarski R. Neurodegeneration induces upregulation of Beclin 1. Autophagy 2006, 2:49-51.
-
(2006)
Autophagy
, vol.2
, pp. 49-51
-
-
Erlich, S.1
Shohami, E.2
Pinkas-Kramarski, R.3
-
12
-
-
0033622324
-
Intraneuronal Abeta42 accumulation in human brain
-
Gouras G.K., Tsai J., Naslund J., Vincent B., Edgar M., Checler F., Greenfield J.P., Haroutunian V., Buxbaum J.D., Xu H., Greengard P., Relkin N.R. Intraneuronal Abeta42 accumulation in human brain. Am. J. Pathol 2000, 156:15-20.
-
(2000)
Am. J. Pathol
, vol.156
, pp. 15-20
-
-
Gouras, G.K.1
Tsai, J.2
Naslund, J.3
Vincent, B.4
Edgar, M.5
Checler, F.6
Greenfield, J.P.7
Haroutunian, V.8
Buxbaum, J.D.9
Xu, H.10
Greengard, P.11
Relkin, N.R.12
-
13
-
-
77149165423
-
LPYFDa neutralizes amyloid-beta-induced memory impairment and toxicity
-
Granic I., Masman M.F., Kees Mulder C., Nijholt I.M., Naude P.J., de Haan A., Borbély E., Penke B., Luiten P.G., Eisel U.L. LPYFDa neutralizes amyloid-beta-induced memory impairment and toxicity. J. Alzheimers Dis 2010, 19:991-1005.
-
(2010)
J. Alzheimers Dis
, vol.19
, pp. 991-1005
-
-
Granic, I.1
Masman, M.F.2
Kees Mulder, C.3
Nijholt, I.M.4
Naude, P.J.5
de Haan, A.6
Borbély, E.7
Penke, B.8
Luiten, P.G.9
Eisel, U.L.10
-
14
-
-
0026735070
-
Targeting of cell-surface beta-amyloid precursor protein to lysosomes: alternative processing into amyloid-bearing fragments
-
Haass C., Koo E.H., Mellon A., Hung A.Y., Selkoe D.J. Targeting of cell-surface beta-amyloid precursor protein to lysosomes: alternative processing into amyloid-bearing fragments. Nature 1992, 357:500-503.
-
(1992)
Nature
, vol.357
, pp. 500-503
-
-
Haass, C.1
Koo, E.H.2
Mellon, A.3
Hung, A.Y.4
Selkoe, D.J.5
-
15
-
-
0344081177
-
Minireview: the AMP-activated protein kinase cascade: the key sensor of cellular energy status
-
Hardie D.G. Minireview: the AMP-activated protein kinase cascade: the key sensor of cellular energy status. Endocrinology 2003, 144:5179-5183.
-
(2003)
Endocrinology
, vol.144
, pp. 5179-5183
-
-
Hardie, D.G.1
-
16
-
-
0345107247
-
Complexes between the LKB1 tumor suppressor, STRAD alpha/beta and MO25 alpha/beta are upstream kinases in the AMP-activated protein kinase cascade
-
Hawley S.A., Boudeau J., Reid J.L., Mustard K.J., Udd L., Mäkelä T.P., Alessi D.R., Hardie D.G. Complexes between the LKB1 tumor suppressor, STRAD alpha/beta and MO25 alpha/beta are upstream kinases in the AMP-activated protein kinase cascade. J. Biol 2003, 2:28.
-
(2003)
J. Biol
, vol.2
, pp. 28
-
-
Hawley, S.A.1
Boudeau, J.2
Reid, J.L.3
Mustard, K.J.4
Udd, L.5
Mäkelä, T.P.6
Alessi, D.R.7
Hardie, D.G.8
-
17
-
-
0033603241
-
RAGE mediates a novel proinflammatory axis: a central cell surface receptor for S100/calgranulin polypeptides
-
Hofmann M.A., Drury S., Fu C., Qu W., Taguchi A., Lu Y., Avila C., Kambham N., Bierhaus A., Nawroth P., Neurath M.F., Slattery T., Beach D., McClary J., Nagashima M., Morser J., Stern D., Schmidt A.M. RAGE mediates a novel proinflammatory axis: a central cell surface receptor for S100/calgranulin polypeptides. Cell 1999, 97:889-901.
-
(1999)
Cell
, vol.97
, pp. 889-901
-
-
Hofmann, M.A.1
Drury, S.2
Fu, C.3
Qu, W.4
Taguchi, A.5
Lu, Y.6
Avila, C.7
Kambham, N.8
Bierhaus, A.9
Nawroth, P.10
Neurath, M.F.11
Slattery, T.12
Beach, D.13
McClary, J.14
Nagashima, M.15
Morser, J.16
Stern, D.17
Schmidt, A.M.18
-
18
-
-
23044432463
-
Calmodulin-dependent protein kinase kinase-beta is an alternative upstream kinase for AMP-activated protein kinase
-
Hawley S.A., Pan D.A., Mustard K.J., Ross L., Bain J., Edelman A.M., Frenguelli B.G., Hardie D.G. Calmodulin-dependent protein kinase kinase-beta is an alternative upstream kinase for AMP-activated protein kinase. Cell Metab 2005, 2:9-19.
-
(2005)
Cell Metab
, vol.2
, pp. 9-19
-
-
Hawley, S.A.1
Pan, D.A.2
Mustard, K.J.3
Ross, L.4
Bain, J.5
Edelman, A.M.6
Frenguelli, B.G.7
Hardie, D.G.8
-
19
-
-
78650668291
-
FK506 reduces amyloid plaque burden and induces MMP-9 in AβPP/PS1 double transgenic mice
-
Hong H.S., Hwang J.Y., Son S.M., Kim Y.H., Moon M., Inhee M.J. FK506 reduces amyloid plaque burden and induces MMP-9 in AβPP/PS1 double transgenic mice. J. Alzheimers Dis 2010, 22:97-105.
-
(2010)
J. Alzheimers Dis
, vol.22
, pp. 97-105
-
-
Hong, H.S.1
Hwang, J.Y.2
Son, S.M.3
Kim, Y.H.4
Moon, M.5
Inhee, M.J.6
-
20
-
-
0028851635
-
The receptor for advanced glycation end products (RAGE) is a cellular binding site for amphoterin. Mediation of neurite outgrowth and co-expression of rage and amphoterin in the developing nervous system
-
Hori O., Brett J., Slattery T., Cao R., Zhang J., Chen J.X., Nagashima M., Lundh E.R., Vijay S., Nitecki D., et al. The receptor for advanced glycation end products (RAGE) is a cellular binding site for amphoterin. Mediation of neurite outgrowth and co-expression of rage and amphoterin in the developing nervous system. J. Biol. Chem 1995, 270:25752-25761.
-
(1995)
J. Biol. Chem
, vol.270
, pp. 25752-25761
-
-
Hori, O.1
Brett, J.2
Slattery, T.3
Cao, R.4
Zhang, J.5
Chen, J.X.6
Nagashima, M.7
Lundh, E.R.8
Vijay, S.9
Nitecki, D.10
-
21
-
-
0029742199
-
Correlative memory deficits, Abeta elevation, and amyloid plaques in transgenic mice
-
Hsiao K., Chapman P., Nilsen S., Eckman C., Harigaya Y., Younkin S., Yang F., Cole G. Correlative memory deficits, Abeta elevation, and amyloid plaques in transgenic mice. Science 1996, 274:99-102.
-
(1996)
Science
, vol.274
, pp. 99-102
-
-
Hsiao, K.1
Chapman, P.2
Nilsen, S.3
Eckman, C.4
Harigaya, Y.5
Younkin, S.6
Yang, F.7
Cole, G.8
-
22
-
-
1642555780
-
Mutant presenilins specifically elevate the levels of the 42 residue beta-amyloid peptide in vivo: evidence for augmentation of a 42-specific gamma secretase
-
Jankowsky J.L., Fadale D.J., Anderson J., Xu G.M., Gonzales V., Jenkins N.A., Copeland N.G., Lee M.K., Younkin L.H., Wagner S.L., Younkin S.G., Borchelt D.R. Mutant presenilins specifically elevate the levels of the 42 residue beta-amyloid peptide in vivo: evidence for augmentation of a 42-specific gamma secretase. Hum. Mol. Genet 2004, 13:159-170.
-
(2004)
Hum. Mol. Genet
, vol.13
, pp. 159-170
-
-
Jankowsky, J.L.1
Fadale, D.J.2
Anderson, J.3
Xu, G.M.4
Gonzales, V.5
Jenkins, N.A.6
Copeland, N.G.7
Lee, M.K.8
Younkin, L.H.9
Wagner, S.L.10
Younkin, S.G.11
Borchelt, D.R.12
-
23
-
-
77949542302
-
The receptor for advanced glycation end products (RAGE) sustains autophagy and limits apoptosis, promoting pancreatic tumor cell survival
-
Kang R., Tang D., Schapiro N.E., Livesey K.M., Farkas A., Loughran P., Bierhaus A., Lotze M.T., Zeh H.J. The receptor for advanced glycation end products (RAGE) sustains autophagy and limits apoptosis, promoting pancreatic tumor cell survival. Cell Death Differ 2010, 17:666-676.
-
(2010)
Cell Death Differ
, vol.17
, pp. 666-676
-
-
Kang, R.1
Tang, D.2
Schapiro, N.E.3
Livesey, K.M.4
Farkas, A.5
Loughran, P.6
Bierhaus, A.7
Lotze, M.T.8
Zeh, H.J.9
-
24
-
-
0037276069
-
A possible linkage between AMP-activated protein kinase (AMPK) and mammalian target of rapamycin (mTOR) signalling pathway
-
Kimura N., Tokunaga C., Dalal S., Richardson C., Yoshino K., Hara K., Kemp B.E., Witters L.A., Mimura O., Yonezawa K. A possible linkage between AMP-activated protein kinase (AMPK) and mammalian target of rapamycin (mTOR) signalling pathway. Genes Cells 2003, 8:65-79.
-
(2003)
Genes Cells
, vol.8
, pp. 65-79
-
-
Kimura, N.1
Tokunaga, C.2
Dalal, S.3
Richardson, C.4
Yoshino, K.5
Hara, K.6
Kemp, B.E.7
Witters, L.A.8
Mimura, O.9
Yonezawa, K.10
-
25
-
-
34548077575
-
Dissection of the autophagosome maturation process by a novel reporter protein, tandem fluorescent-tagged LC3
-
Kimura S., Noda T., Yoshimori T. Dissection of the autophagosome maturation process by a novel reporter protein, tandem fluorescent-tagged LC3. Autophagy 2007, 3:452-460.
-
(2007)
Autophagy
, vol.3
, pp. 452-460
-
-
Kimura, S.1
Noda, T.2
Yoshimori, T.3
-
26
-
-
35448981935
-
Autophagy: from phenomenology to molecular understanding in less than a decade
-
Klionsky D.J. Autophagy: from phenomenology to molecular understanding in less than a decade. Nat. Rev. Mol. Cell Biol 2007, 8:931-937.
-
(2007)
Nat. Rev. Mol. Cell Biol
, vol.8
, pp. 931-937
-
-
Klionsky, D.J.1
-
27
-
-
38949108670
-
Guidelines for the use and interpretation of assays for monitoring autophagy in higher eukaryotes
-
Klionsky D.J., Abeliovich H., Agostinis P., Agrawal D.K., Aliev G., Askew D.S., Baba M., Baehrecke E.H., Bahr B.A., Ballabio A., Bamber B.A., Bassham D.C., Bergamini E., Bi X., Biard-Piechaczyk M., Blum J.S., Bredesen D.E., Brodsky J.L., Brumell J.H., Brunk U.T., Bursch W., Camougrand N., Cebollero E., Cecconi F., Chen Y., Chin L.S., Choi A., Chu C.T., Chung J., Clarke P.G., Clark R.S., Clarke S.G., Clavé C., Cleveland J.L., Codogno P., Colombo M.I., Coto-Montes A., Cregg J.M., Cuervo A.M., Debnath J., Demarchi F., Dennis P.B., Dennis P.A., Deretic V., Devenish R.J., Di Sano F., Dice J.F., Difiglia M., Dinesh-Kumar S., Distelhorst C.W., Djavaheri-Mergny M., Dorsey F.C., Droge W., Dron M., Dunn W.A., Duszenko M., Eissa N.T., Elazar Z., Esclatine A., Eskelinen E.L., Fesus L., Finley K.D., Fuentes J.M., Fueyo J., Fujisaki K., Galliot B., Gao F.B., Gewirtz D.A., Gibson S.B., Gohla A., Goldberg A.L., Gonzalez R., Gonzalez-Estevez C., Gorski S., Gottlieb R.A., Haussinger D., He Y.W., Heidenreich K., Hill J.A., Hoyer-Hansen M., Hu X., Huang W.P., Iwasaki A., Jaattela M., Jackson W.T., Jiang X., Jin S., Johansen T., Jung J.U., Kadowaki M., Kang C., Kelekar A., Kessel D.H., Kiel J.A., Kim H.P., Kimchi A., Kinsella T.J., Kiselyov K., Kitamoto K., Knecht E., Komatsu M., Kominami E., Kondo S., Kovacs A.L., Kroemer G., Kuan C.Y., Kumar R., Kundu M., Landry J., Laporte M., Le W., Lei H.Y., Lenardo M.J., Levine B., Lieberman A., Lim K.L., Lin F.C., Liou W., Liu L.F., Lopez-Berestein G., Lopez-Otin C., Lu B., Macleod K.F., Malorni W., Martinet W., Matsuoka K., Mautner J., Meijer A.J., Melendez A., Michels P., Miotto G., Mistiaen W.P., Mizushima N., Mograbi B., Monastyrska I., Moore M.N., Moreira P.I., Moriyasu Y., Motyl T., Munz C., Murphy L.O., Naqvi N.I., Neufeld T.P., Nishino I., Nixon R.A., Noda T., Nurnberg B., Ogawa M., Oleinick N.L., Olsen L.J., Ozpolat B., Paglin S., Palmer G.E., Papassideri I., Parkes M., Perlmutter D.H., Perry G., Piacentini M., Pinkas-Kramarski R., Prescott M., Proikas-Cezanne T., Raben N., Rami A., Reggiori F., Rohrer B., Rubinsztein D.C., Ryan K.M., Sadoshima J., Sakagami H., Sakai Y., Sandri M., Sasakawa C., Sass M., Schneider C., Seglen P.O., Seleverstov O., Settleman J., Shacka J.J., Shapiro I.M., Sibirny A., Silva-Zacarin E.C., Simon H.U., Simone C., Simonsen A., Smith M.A., Spanel-Borowski K., Srinivas V., Steeves M., Stenmark H., Stromhaug P.E., Subauste C.S., Sugimoto S., Sulzer D., Suzuki T., Swanson M.S., Tabas I., Takeshita F., Talbot N.J., Talloczy Z., Tanaka K., Tanida I., Taylor G.S., Taylor J.P., Terman A., Tettamanti G., Thompson C.B., Thumm M., Tolkovsky A.M., Tooze S.A., Truant R., Tumanovska L.V., Uchiyama Y., Ueno T., Uzcategui N.L., van der Klei I., Vaquero E.C., Vellai T., Vogel M.W., Wang H.G., Webster P., Wiley J.W., Xi Z., Xiao G., Yahalom J., Yang J.M., Yap G., Yin X.M., Yoshimori T., Yu L., Yue Z., Yuzaki M., Zabirnyk O., Zheng X., Zhu X., Deter R.L. Guidelines for the use and interpretation of assays for monitoring autophagy in higher eukaryotes. Autophagy 2008, 4:151-175.
-
(2008)
Autophagy
, vol.4
, pp. 151-175
-
-
Klionsky, D.J.1
Abeliovich, H.2
Agostinis, P.3
Agrawal, D.K.4
Aliev, G.5
Askew, D.S.6
Baba, M.7
Baehrecke, E.H.8
Bahr, B.A.9
Ballabio, A.10
Bamber, B.A.11
Bassham, D.C.12
Bergamini, E.13
Bi, X.14
Biard-Piechaczyk, M.15
Blum, J.S.16
Bredesen, D.E.17
Brodsky, J.L.18
Brumell, J.H.19
Brunk, U.T.20
Bursch, W.21
Camougrand, N.22
Cebollero, E.23
Cecconi, F.24
Chen, Y.25
Chin, L.S.26
Choi, A.27
Chu, C.T.28
Chung, J.29
Clarke, P.G.30
Clark, R.S.31
Clarke, S.G.32
Clavé, C.33
Cleveland, J.L.34
Codogno, P.35
Colombo, M.I.36
Coto-Montes, A.37
Cregg, J.M.38
Cuervo, A.M.39
Debnath, J.40
Demarchi, F.41
Dennis, P.B.42
Dennis, P.A.43
Deretic, V.44
Devenish, R.J.45
Di Sano, F.46
Dice, J.F.47
Difiglia, M.48
Dinesh-Kumar, S.49
Distelhorst, C.W.50
Djavaheri-Mergny, M.51
Dorsey, F.C.52
Droge, W.53
Dron, M.54
Dunn, W.A.55
Duszenko, M.56
Eissa, N.T.57
Elazar, Z.58
Esclatine, A.59
Eskelinen, E.L.60
Fesus, L.61
Finley, K.D.62
Fuentes, J.M.63
Fueyo, J.64
Fujisaki, K.65
Galliot, B.66
Gao, F.B.67
Gewirtz, D.A.68
Gibson, S.B.69
Gohla, A.70
Goldberg, A.L.71
Gonzalez, R.72
Gonzalez-Estevez, C.73
Gorski, S.74
Gottlieb, R.A.75
Haussinger, D.76
He, Y.W.77
Heidenreich, K.78
Hill, J.A.79
Hoyer-Hansen, M.80
Hu, X.81
Huang, W.P.82
Iwasaki, A.83
Jaattela, M.84
Jackson, W.T.85
Jiang, X.86
Jin, S.87
Johansen, T.88
Jung, J.U.89
Kadowaki, M.90
Kang, C.91
Kelekar, A.92
Kessel, D.H.93
Kiel, J.A.94
Kim, H.P.95
Kimchi, A.96
Kinsella, T.J.97
Kiselyov, K.98
Kitamoto, K.99
more..
-
28
-
-
0036364274
-
Control of p70 ribosomal protein S6 kinase and acetyl-CoA carboxylase by AMP-activated protein kinase and protein phosphatases in isolated hepatocytes
-
Krause U., Bertrand L., Hue L. Control of p70 ribosomal protein S6 kinase and acetyl-CoA carboxylase by AMP-activated protein kinase and protein phosphatases in isolated hepatocytes. Eur. J. Biochem 2002, 269:3751-3759.
-
(2002)
Eur. J. Biochem
, vol.269
, pp. 3751-3759
-
-
Krause, U.1
Bertrand, L.2
Hue, L.3
-
29
-
-
77954421886
-
SU11248 (sunitinib) directly inhibits the activity of mammalian 5'-AMP-activated protein kinase (AMPK)
-
Laderoute K.R., Calaoagan J.M., Madrid P.B., Klon A.E., Ehrlich P.J. SU11248 (sunitinib) directly inhibits the activity of mammalian 5'-AMP-activated protein kinase (AMPK). Cancer Biol. Ther 2010, 10:68-76.
-
(2010)
Cancer Biol. Ther
, vol.10
, pp. 68-76
-
-
Laderoute, K.R.1
Calaoagan, J.M.2
Madrid, P.B.3
Klon, A.E.4
Ehrlich, P.J.5
-
30
-
-
33947250696
-
The energy sensing LKB1-AMPK pathway regulates p27(kip1) phosphorylation mediating the decision to enter autophagy or apoptosis
-
Liang J., Shao S.H., Xu Z.X., Hennessy B., Ding Z., Larrea M., Kondo S., Dumont D.J., Gutterman J.U., Walker C.L., Slingerland J.M., Mills G.B. The energy sensing LKB1-AMPK pathway regulates p27(kip1) phosphorylation mediating the decision to enter autophagy or apoptosis. Nat. Cell Biol 2007, 9:218-224.
-
(2007)
Nat. Cell Biol
, vol.9
, pp. 218-224
-
-
Liang, J.1
Shao, S.H.2
Xu, Z.X.3
Hennessy, B.4
Ding, Z.5
Larrea, M.6
Kondo, S.7
Dumont, D.J.8
Gutterman, J.U.9
Walker, C.L.10
Slingerland, J.M.11
Mills, G.B.12
-
31
-
-
58449101589
-
Abeta42-induced neurodegeneration via an age-dependent autophagic-lysosomal injury in Drosophila
-
Ling D., Song H.J., Garza D., Neufeld T.P., Salvaterra P.M. Abeta42-induced neurodegeneration via an age-dependent autophagic-lysosomal injury in Drosophila. PLoS One 2009, 4:e4201.
-
(2009)
PLoS One
, vol.4
-
-
Ling, D.1
Song, H.J.2
Garza, D.3
Neufeld, T.P.4
Salvaterra, P.M.5
-
32
-
-
33846590099
-
Disturbed cross talk between insulin-like growth factor I and AMP-activated protein kinase as a possible cause of vascular dysfunction in the amyloid precursor protein/presenilin 2 mouse model of Alzheimer's disease
-
Lopez-Lopez C., Dietrich M.O., Metzger F., Loetscher H., Torres-Aleman I. Disturbed cross talk between insulin-like growth factor I and AMP-activated protein kinase as a possible cause of vascular dysfunction in the amyloid precursor protein/presenilin 2 mouse model of Alzheimer's disease. J. Neurosci 2007, 27:824-831.
-
(2007)
J. Neurosci
, vol.27
, pp. 824-831
-
-
Lopez-Lopez, C.1
Dietrich, M.O.2
Metzger, F.3
Loetscher, H.4
Torres-Aleman, I.5
-
33
-
-
0034840664
-
Involvement of microglial receptor for advanced glycation endproducts (RAGE) in Alzheimer's disease: identification of a cellular activation mechanism
-
Lue L.F., Walker D.G., Brachova L., Beach T.G., Rogers J., Schmidt A.M., Stern D.M., Yan S.D. Involvement of microglial receptor for advanced glycation endproducts (RAGE) in Alzheimer's disease: identification of a cellular activation mechanism. Exp. Neurol 2001, 171:29-45.
-
(2001)
Exp. Neurol
, vol.171
, pp. 29-45
-
-
Lue, L.F.1
Walker, D.G.2
Brachova, L.3
Beach, T.G.4
Rogers, J.5
Schmidt, A.M.6
Stern, D.M.7
Yan, S.D.8
-
34
-
-
0032529151
-
Human blood-brain barrier receptors for Alzheimer's amyloid-beta 1-40. Asymmetrical binding, endocytosis, and transcytosis at the apical side of brain microvascular endothelial cell monolayer
-
Mackic J.B., Stins M., McComb J.G., Calero M., Ghiso J., Kim K.S., Yan S.D., Stern D., Schmidt A.M., Frangione B., Zlokovic B.V. Human blood-brain barrier receptors for Alzheimer's amyloid-beta 1-40. Asymmetrical binding, endocytosis, and transcytosis at the apical side of brain microvascular endothelial cell monolayer. J. Clin. Invest 1998, 102:734-743.
-
(1998)
J. Clin. Invest
, vol.102
, pp. 734-743
-
-
Mackic, J.B.1
Stins, M.2
McComb, J.G.3
Calero, M.4
Ghiso, J.5
Kim, K.S.6
Yan, S.D.7
Stern, D.8
Schmidt, A.M.9
Frangione, B.10
Zlokovic, B.V.11
-
35
-
-
0034687210
-
Phosphorylation and activation of heart PFK-2 by AMPK has a role in the stimulation of glycolysis during ischaemia
-
Marsin A.S., Bertrand L., Rider M.H., Deprez J., Beauloye C., Vincent M.F., Van den Berghe G., Carling D., Hue L. Phosphorylation and activation of heart PFK-2 by AMPK has a role in the stimulation of glycolysis during ischaemia. Curr. Biol 2000, 10:1247-1255.
-
(2000)
Curr. Biol
, vol.10
, pp. 1247-1255
-
-
Marsin, A.S.1
Bertrand, L.2
Rider, M.H.3
Deprez, J.4
Beauloye, C.5
Vincent, M.F.6
Van den Berghe, G.7
Carling, D.8
Hue, L.9
-
36
-
-
34147168105
-
Distinct roles of autophagy in the heart during ischemia and reperfusion: roles of AMP-activated protein kinase and Beclin 1 in mediating autophagy
-
Matsui Y., Takagi H., Qu X., Abdellatif M., Sakoda H., Asano T., Levine B., Sadoshima J. Distinct roles of autophagy in the heart during ischemia and reperfusion: roles of AMP-activated protein kinase and Beclin 1 in mediating autophagy. Circ. Res 2007, 100:914-922.
-
(2007)
Circ. Res
, vol.100
, pp. 914-922
-
-
Matsui, Y.1
Takagi, H.2
Qu, X.3
Abdellatif, M.4
Sakoda, H.5
Asano, T.6
Levine, B.7
Sadoshima, J.8
-
37
-
-
0026570528
-
Beta-Amyloid peptides destabilize calcium homeostasis and render human cortical neurons vulnerable to excitotoxicity
-
Mattson M.P., Cheng B., Davis D., Bryant K., Lieberburg I., Rydel R.E. beta-Amyloid peptides destabilize calcium homeostasis and render human cortical neurons vulnerable to excitotoxicity. J. Neurosci 1992, 12:376-389.
-
(1992)
J. Neurosci
, vol.12
, pp. 376-389
-
-
Mattson, M.P.1
Cheng, B.2
Davis, D.3
Bryant, K.4
Lieberburg, I.5
Rydel, R.E.6
-
38
-
-
33845924783
-
AMP-activated protein kinase and the regulation of autophagic proteolysis
-
Meley D., Bauvy C., Houben-Weerts J.H., Dubbelhuis P.F., Helmond M.T., Codogno P., Meijer A.J. AMP-activated protein kinase and the regulation of autophagic proteolysis. J. Biol. Chem 2006, 281:34870-34879.
-
(2006)
J. Biol. Chem
, vol.281
, pp. 34870-34879
-
-
Meley, D.1
Bauvy, C.2
Houben-Weerts, J.H.3
Dubbelhuis, P.F.4
Helmond, M.T.5
Codogno, P.6
Meijer, A.J.7
-
39
-
-
4344712684
-
Methods for monitoring autophagy
-
Mizushima N. Methods for monitoring autophagy. Int. J. Biochem. Cell Biol 2004, 36:2491-2502.
-
(2004)
Int. J. Biochem. Cell Biol
, vol.36
, pp. 2491-2502
-
-
Mizushima, N.1
-
40
-
-
78651359641
-
Ghrelin ameliorates cognitive dysfunction and neurodegeneration in intrahippocampal amyloid-β1-42 oligomer-injected mice
-
Moon M., Choi J.G., Nam D.W., Hong H.S., Choi Y.J., Oh M.S., Mook-Jung I. Ghrelin ameliorates cognitive dysfunction and neurodegeneration in intrahippocampal amyloid-β1-42 oligomer-injected mice. J. Alzheimers Dis 2011, 23:147-159.
-
(2011)
J. Alzheimers Dis
, vol.23
, pp. 147-159
-
-
Moon, M.1
Choi, J.G.2
Nam, D.W.3
Hong, H.S.4
Choi, Y.J.5
Oh, M.S.6
Mook-Jung, I.7
-
41
-
-
0026659883
-
Cloning and expression of a cell surface receptor for advanced glycosylation end products of proteins
-
Neeper M., Schmidt A.M., Brett J., Yan S.D., Wang F., Pan Y.C., Elliston K., Stern D., Shaw A. Cloning and expression of a cell surface receptor for advanced glycosylation end products of proteins. J. Biol. Chem 1992, 267:14998-15004.
-
(1992)
J. Biol. Chem
, vol.267
, pp. 14998-15004
-
-
Neeper, M.1
Schmidt, A.M.2
Brett, J.3
Yan, S.D.4
Wang, F.5
Pan, Y.C.6
Elliston, K.7
Stern, D.8
Shaw, A.9
-
42
-
-
33747881231
-
Autophagy in neurodegenerative disease: friend, foe or turncoat?
-
Nixon R.A. Autophagy in neurodegenerative disease: friend, foe or turncoat?. Trends Neurosci 2006, 29:528-535.
-
(2006)
Trends Neurosci
, vol.29
, pp. 528-535
-
-
Nixon, R.A.1
-
43
-
-
14844303381
-
Extensive involvement of autophagy in Alzheimer disease: an immuno-electron microscopy study
-
Nixon R.A., Wegiel J., Kumar A., Yu W.H., Peterhoff C., Cataldo A., Cuervo A.M. Extensive involvement of autophagy in Alzheimer disease: an immuno-electron microscopy study. J. Neuropathol. Exp. Neurol 2005, 64:113-122.
-
(2005)
J. Neuropathol. Exp. Neurol
, vol.64
, pp. 113-122
-
-
Nixon, R.A.1
Wegiel, J.2
Kumar, A.3
Yu, W.H.4
Peterhoff, C.5
Cataldo, A.6
Cuervo, A.M.7
-
44
-
-
0037698096
-
Presenilin-1, nicastrin, amyloid precursor protein, and gamma-secretase activity are co-localized in the lysosomal membrane
-
Pasternak S.H., Bagshaw R.D., Guiral M., Zhang S., Ackerley C.A., Pak B.J., Callahan J.W., Mahuran D.J. Presenilin-1, nicastrin, amyloid precursor protein, and gamma-secretase activity are co-localized in the lysosomal membrane. J. Biol. Chem 2003, 278:26687-26694.
-
(2003)
J. Biol. Chem
, vol.278
, pp. 26687-26694
-
-
Pasternak, S.H.1
Bagshaw, R.D.2
Guiral, M.3
Zhang, S.4
Ackerley, C.A.5
Pak, B.J.6
Callahan, J.W.7
Mahuran, D.J.8
-
45
-
-
33750363298
-
The roles of intracellular protein-degradation pathways in neurodegeneration
-
Rubinsztein D.C. The roles of intracellular protein-degradation pathways in neurodegeneration. Nature 2006, 443:780-786.
-
(2006)
Nature
, vol.443
, pp. 780-786
-
-
Rubinsztein, D.C.1
-
46
-
-
0032213768
-
AMP-activated protein kinase is activated by low glucose in cell lines derived from pancreatic beta cells, and may regulate insulin release
-
Salt I.P., Johnson G., Ashcroft S.J., Hardie D.G. AMP-activated protein kinase is activated by low glucose in cell lines derived from pancreatic beta cells, and may regulate insulin release. Biochem. J 1998, 335:533-539.
-
(1998)
Biochem. J
, vol.335
, pp. 533-539
-
-
Salt, I.P.1
Johnson, G.2
Ashcroft, S.J.3
Hardie, D.G.4
-
47
-
-
0034644525
-
TOR, a central controller of cell growth
-
Schmelzle T., Hall M.N. TOR, a central controller of cell growth. Cell 2000, 103:253-262.
-
(2000)
Cell
, vol.103
, pp. 253-262
-
-
Schmelzle, T.1
Hall, M.N.2
-
48
-
-
0034795140
-
The multiligand receptor RAGE as a progression factor amplifying immune and inflammatory responses
-
Schmidt A.M., Yan S.D., Yan S.F., Stern D.M. The multiligand receptor RAGE as a progression factor amplifying immune and inflammatory responses. J. Clin. Invest 2001, 108:949-955.
-
(2001)
J. Clin. Invest
, vol.108
, pp. 949-955
-
-
Schmidt, A.M.1
Yan, S.D.2
Yan, S.F.3
Stern, D.M.4
-
49
-
-
7944233158
-
Cell biology of protein misfolding: the examples of Alzheimer's and Parkinson's diseases
-
Selkoe D.J. Cell biology of protein misfolding: the examples of Alzheimer's and Parkinson's diseases. Nat. Cell Biol 2004, 6:1054-1061.
-
(2004)
Nat. Cell Biol
, vol.6
, pp. 1054-1061
-
-
Selkoe, D.J.1
-
50
-
-
0033595706
-
Beta-secretase cleavage of Alzheimer's amyloid precursor protein by the transmembrane aspartic protease BACE
-
Vassar R., Bennett B.D., Babu-Khan S., Kahn S., Mendiaz E.A., Denis P., Teplow D.B., Ross S., Amarante P., Loeloff R., Luo Y., Fisher S., Fuller J., Edenson S., Lile J., Jarosinski M.A., Biere A.L., Curran E., Burgess T., Louis J.C., Collins F., Treanor J., Rogers G., Citron M. Beta-secretase cleavage of Alzheimer's amyloid precursor protein by the transmembrane aspartic protease BACE. Science 1999, 286:735-741.
-
(1999)
Science
, vol.286
, pp. 735-741
-
-
Vassar, R.1
Bennett, B.D.2
Babu-Khan, S.3
Kahn, S.4
Mendiaz, E.A.5
Denis, P.6
Teplow, D.B.7
Ross, S.8
Amarante, P.9
Loeloff, R.10
Luo, Y.11
Fisher, S.12
Fuller, J.13
Edenson, S.14
Lile, J.15
Jarosinski, M.A.16
Biere, A.L.17
Curran, E.18
Burgess, T.19
Louis, J.C.20
Collins, F.21
Treanor, J.22
Rogers, G.23
Citron, M.24
more..
-
51
-
-
41249091730
-
Role of AMP-activated protein kinase in autophagy and proteasome function
-
Viana R., Aguado C., Esteban I., Moreno D., Viollet B., Knecht E., Sanz P. Role of AMP-activated protein kinase in autophagy and proteasome function. Biochem. Biophys. Res. Commun 2008, 369:964-968.
-
(2008)
Biochem. Biophys. Res. Commun
, vol.369
, pp. 964-968
-
-
Viana, R.1
Aguado, C.2
Esteban, I.3
Moreno, D.4
Viollet, B.5
Knecht, E.6
Sanz, P.7
-
52
-
-
5344277556
-
Deciphering the molecular basis of memory failure in Alzheimer's disease
-
Walsh D.M., Selkoe D.J. Deciphering the molecular basis of memory failure in Alzheimer's disease. Neuron 2004, 44:181-193.
-
(2004)
Neuron
, vol.44
, pp. 181-193
-
-
Walsh, D.M.1
Selkoe, D.J.2
-
53
-
-
23044437445
-
Ca2+/calmodulin-dependent protein kinase kinase-beta acts upstream of AMP-activated protein kinase in mammalian cells
-
Woods A., Dickerson K., Heath R., Hong S.P., Momcilovic M., Johnstone S.R., Carlson M., Carling D. Ca2+/calmodulin-dependent protein kinase kinase-beta acts upstream of AMP-activated protein kinase in mammalian cells. Cell Metab 2005, 2:21-33.
-
(2005)
Cell Metab
, vol.2
, pp. 21-33
-
-
Woods, A.1
Dickerson, K.2
Heath, R.3
Hong, S.P.4
Momcilovic, M.5
Johnstone, S.R.6
Carlson, M.7
Carling, D.8
-
54
-
-
0031593675
-
Bafilomycin A1 prevents maturation of autophagic vacuoles by inhibiting fusion between autophagosomes and lysosomes in rat hepatoma cell line, H-4-II-E cells
-
Yamamoto A., Tagawa Y., Yoshimori T., Moriyama Y., Masaki R., Tashiro Y. Bafilomycin A1 prevents maturation of autophagic vacuoles by inhibiting fusion between autophagosomes and lysosomes in rat hepatoma cell line, H-4-II-E cells. Cell Struct. Funct 1998, 23:33-42.
-
(1998)
Cell Struct. Funct
, vol.23
, pp. 33-42
-
-
Yamamoto, A.1
Tagawa, Y.2
Yoshimori, T.3
Moriyama, Y.4
Masaki, R.5
Tashiro, Y.6
-
55
-
-
0013615899
-
RAGE and amyloid-beta peptide neurotoxicity in Alzheimer's disease
-
Yan S.D., Chen X., Fu J., Chen M., Zhu H., Roher A., Slattery T., Zhao L., Nagashima M., Morser J., Migheli A., Nawroth P., Stern D., Schmidt A.M. RAGE and amyloid-beta peptide neurotoxicity in Alzheimer's disease. Nature 1996, 382:685-691.
-
(1996)
Nature
, vol.382
, pp. 685-691
-
-
Yan, S.D.1
Chen, X.2
Fu, J.3
Chen, M.4
Zhu, H.5
Roher, A.6
Slattery, T.7
Zhao, L.8
Nagashima, M.9
Morser, J.10
Migheli, A.11
Nawroth, P.12
Stern, D.13
Schmidt, A.M.14
-
56
-
-
0034718230
-
Cellular cofactors potentiating induction of stress and cytotoxicity by amyloid beta-peptide
-
Yan S.D., Roher A., Chaney M., Zlokovic B., Schmidt A.M., Stern D. Cellular cofactors potentiating induction of stress and cytotoxicity by amyloid beta-peptide. Biochim. Biophys. Acta 2000, 1502:145-157.
-
(2000)
Biochim. Biophys. Acta
, vol.1502
, pp. 145-157
-
-
Yan, S.D.1
Roher, A.2
Chaney, M.3
Zlokovic, B.4
Schmidt, A.M.5
Stern, D.6
-
57
-
-
0031821610
-
RAGE-Abeta interactions in the pathophysiology of Alzheimer's disease
-
Yan S.D., Stern D., Kane M.D., Kuo Y.M., Lampert H.C., Roher A.E. RAGE-Abeta interactions in the pathophysiology of Alzheimer's disease. Restor. Neurol. Neurosci 1998, 12:167-173.
-
(1998)
Restor. Neurol. Neurosci
, vol.12
, pp. 167-173
-
-
Yan, S.D.1
Stern, D.2
Kane, M.D.3
Kuo, Y.M.4
Lampert, H.C.5
Roher, A.E.6
-
58
-
-
0029896354
-
Mechanisms of neuronal degeneration in Alzheimer's disease
-
Yankner B.A. Mechanisms of neuronal degeneration in Alzheimer's disease. Neuron 1996, 16:921-932.
-
(1996)
Neuron
, vol.16
, pp. 921-932
-
-
Yankner, B.A.1
-
59
-
-
26444587508
-
Macroautophagy-a novel Beta-amyloid peptide-generating pathway activated in Alzheimer's disease
-
Yu W.H., Cuervo A.M., Kumar A., Peterhoff C.M., Schmidt S.D., Lee J.H., Mohan P.S., Mercken M., Farmery M.R., Tjernberg L.O., Jiang Y., Duff K., Uchiyama Y., Näslund J., Mathews P.M., Cataldo A.M., Nixon R.A. Macroautophagy-a novel Beta-amyloid peptide-generating pathway activated in Alzheimer's disease. J. Cell Biol 2005, 171:87-98.
-
(2005)
J. Cell Biol
, vol.171
, pp. 87-98
-
-
Yu, W.H.1
Cuervo, A.M.2
Kumar, A.3
Peterhoff, C.M.4
Schmidt, S.D.5
Lee, J.H.6
Mohan, P.S.7
Mercken, M.8
Farmery, M.R.9
Tjernberg, L.O.10
Jiang, Y.11
Duff, K.12
Uchiyama, Y.13
Näslund, J.14
Mathews, P.M.15
Cataldo, A.M.16
Nixon, R.A.17
-
60
-
-
0034773404
-
Role of AMP-activated protein kinase in mechanism of metformin action
-
Zhou G., Myers R., Li Y., Chen Y., Shen X., Fenyk-Melody J., Wu M., Ventre J., Doebber T., Fujii N., Musi N., Hirshman M.F., Goodyear L.J., Moller D.E. Role of AMP-activated protein kinase in mechanism of metformin action. J. Clin. Invest 2001, 108:1167-1174.
-
(2001)
J. Clin. Invest
, vol.108
, pp. 1167-1174
-
-
Zhou, G.1
Myers, R.2
Li, Y.3
Chen, Y.4
Shen, X.5
Fenyk-Melody, J.6
Wu, M.7
Ventre, J.8
Doebber, T.9
Fujii, N.10
Musi, N.11
Hirshman, M.F.12
Goodyear, L.J.13
Moller, D.E.14
|