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Volumn 234, Issue 3, 2019, Pages 2143-2151

Modulation of the immune response by Middle East respiratory syndrome coronavirus

Author keywords

immune evasion; immune response; Middle East respiratory syndrome coronavirus

Indexed keywords

DOUBLE STRANDED RNA; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERFERON; INTERLEUKIN 10; M PROTEIN; MONOCYTE CHEMOTACTIC PROTEIN 1; NONSTRUCTURAL PROTEIN 15; NONSTRUCTURAL PROTEIN 4A; NONSTRUCTURAL PROTEIN 4B; PAPAIN; PAPAIN LIKE PROTEASE UBIQUITIN LIKE DOMAIN; UNCLASSIFIED DRUG; VIRAL PROTEIN; VIRUS RNA;

EID: 85052378077     PISSN: 00219541     EISSN: 10974652     Source Type: Journal    
DOI: 10.1002/jcp.27155     Document Type: Review
Times cited : (78)

References (77)
  • 1
    • 84891145091 scopus 로고    scopus 로고
    • Middle East respiratory syndrome coronavirus (MERS-CoV): A perpetual challenge
    • Al Hajjar, S., Memish, Z. A., & Mcintosh, K. (2013). Middle East respiratory syndrome coronavirus (MERS-CoV): A perpetual challenge. Annals of Saudi Medicine, 33(5), 427–436.
    • (2013) Annals of Saudi Medicine , vol.33 , Issue.5 , pp. 427-436
    • Al Hajjar, S.1    Memish, Z.A.2    Mcintosh, K.3
  • 2
    • 0033831421 scopus 로고    scopus 로고
    • Viral mechanisms of immune evasion
    • Alcami, A., & Koszinowski, U. H. (2000). Viral mechanisms of immune evasion. Immunology Today, 21(9), 447–455.
    • (2000) Immunology Today , vol.21 , Issue.9 , pp. 447-455
    • Alcami, A.1    Koszinowski, U.H.2
  • 3
    • 84887148359 scopus 로고    scopus 로고
    • Engineering a replication-competent, propagation-defective Middle East respiratory syndrome coronavirus as a vaccine candidate
    • Almazan, F., DeDiego, M. L., Sola, I., Zuniga, S., Nieto-Torres, J. L., Marquez-Jurado, S., … Enjuanes, L. (2013). Engineering a replication-competent, propagation-defective Middle East respiratory syndrome coronavirus as a vaccine candidate. mBio, 4(5), e00650–00613.
    • (2013) mBio , vol.4 , Issue.5 , pp. e00613-e00650
    • Almazan, F.1    DeDiego, M.L.2    Sola, I.3    Zuniga, S.4    Nieto-Torres, J.L.5    Marquez-Jurado, S.6    Enjuanes, L.7
  • 4
    • 85052372729 scopus 로고    scopus 로고
    • The middle east respiratory syndrome coronavirus respiratory infection: An emerging infection from the Arabian Peninsula
    • Elsevier
    • Al-Tawfiq, J., & Memish, Z. (2016). The middle east respiratory syndrome coronavirus respiratory infection: An emerging infection from the Arabian Peninsula, The Microbiology of Respiratory System Infections (pp. 55–63). Elsevier.
    • (2016) The Microbiology of Respiratory System Infections , pp. 55-63
    • Al-Tawfiq, J.1    Memish, Z.2
  • 5
    • 84883448281 scopus 로고    scopus 로고
    • Spiking the MERS-coronavirus receptor
    • Bosch, B. J., Raj, V. S., & Haagmans, B. L. (2013). Spiking the MERS-coronavirus receptor. Cell Research, 23(9), 1069–1070.
    • (2013) Cell Research , vol.23 , Issue.9 , pp. 1069-1070
    • Bosch, B.J.1    Raj, V.S.2    Haagmans, B.L.3
  • 6
    • 0027300330 scopus 로고
    • Comparative analysis of the human macrophage inflammatory protein family of cytokines (chemokines) on proliferation of human myeloid progenitor cells. Interacting effects involving suppression, synergistic suppression, and blocking of suppression
    • Broxmeyer, H. E., Sherry, B., Cooper, S., Lu, L., Maze, R., Beckmann, M. P., … Ralph, P. (1993). Comparative analysis of the human macrophage inflammatory protein family of cytokines (chemokines) on proliferation of human myeloid progenitor cells. Interacting effects involving suppression, synergistic suppression, and blocking of suppression. The Journal of Immunology, 150(8), 3448–3458.
    • (1993) The Journal of Immunology , vol.150 , Issue.8 , pp. 3448-3458
    • Broxmeyer, H.E.1    Sherry, B.2    Cooper, S.3    Lu, L.4    Maze, R.5    Beckmann, M.P.6    Ralph, P.7
  • 7
    • 84881551712 scopus 로고    scopus 로고
    • The emerging novel Middle East respiratory syndrome coronavirus: The “knowns” and “unknowns”
    • Chan, J. F.-W., Lau, S. K.-P., & Woo, P. C.-Y. (2013). The emerging novel Middle East respiratory syndrome coronavirus: The “knowns” and “unknowns”. Journal of the Formosan Medical Association, 112(7), 372–381.
    • (2013) Journal of the Formosan Medical Association , vol.112 , Issue.7 , pp. 372-381
    • Chan, J.F.W.1    Lau, S.K.P.2    Woo, P.C.Y.3
  • 8
    • 85020378994 scopus 로고    scopus 로고
    • Comparative epidemiology of Middle East respiratory syndrome coronavirus (MERS-CoV) in Saudi Arabia and South Korea
    • Chen, X., Chughtai, A. A., Dyda, A., & MacIntyre, C. R. (2017). Comparative epidemiology of Middle East respiratory syndrome coronavirus (MERS-CoV) in Saudi Arabia and South Korea. Emerging Microbes & Infections, 6(6), e51.
    • (2017) Emerging Microbes & Infections , vol.6 , Issue.6
    • Chen, X.1    Chughtai, A.A.2    Dyda, A.3    MacIntyre, C.R.4
  • 9
    • 84964577738 scopus 로고    scopus 로고
    • Macro domain from Middle East respiratory syndrome coronavirus (MERS-CoV) is an efficient ADP-ribose binding module crystal structure and biochemical studies
    • Cho, C.-C., Lin, M.-H., Chuang, C.-Y., & Hsu, C.-H. (2016). Macro domain from Middle East respiratory syndrome coronavirus (MERS-CoV) is an efficient ADP-ribose binding module crystal structure and biochemical studies. Journal of Biological Chemistry, 291(10), 4894–4902.
    • (2016) Journal of Biological Chemistry , vol.291 , Issue.10 , pp. 4894-4902
    • Cho, C.-C.1    Lin, M.-H.2    Chuang, C.-Y.3    Hsu, C.-H.4
  • 10
    • 84895742275 scopus 로고    scopus 로고
    • Productive replication of Middle East respiratory syndrome coronavirus in monocyte-derived dendritic cells modulates innate immune response
    • [Supplement C].
    • Chu, H., Zhou, J., Ho-Yin Wong, B., Li, C., Cheng, Z.-S., Lin, X., … Yuen, K.-Y. (2014). Productive replication of Middle East respiratory syndrome coronavirus in monocyte-derived dendritic cells modulates innate immune response. Virology, 454-455, 197–205. [Supplement C].
    • (2014) Virology , vol.454-455 , pp. 197-205
    • Chu, H.1    Zhou, J.2    Ho-Yin Wong, B.3    Li, C.4    Cheng, Z.-S.5    Lin, X.6    Yuen, K.-Y.7
  • 11
    • 84964848410 scopus 로고    scopus 로고
    • Middle East respiratory syndrome coronavirus efficiently infects human primary T lymphocytes and activates the extrinsic and intrinsic apoptosis pathways
    • Chu, H., Zhou, J., Wong, B. H.-Y., Li, C., Chan, J. F.-W., Cheng, Z.-S., … Yuen, K. Y. (2015). Middle East respiratory syndrome coronavirus efficiently infects human primary T lymphocytes and activates the extrinsic and intrinsic apoptosis pathways. The Journal of Infectious Diseases, 213(6), 904–914.
    • (2015) The Journal of Infectious Diseases , vol.213 , Issue.6 , pp. 904-914
    • Chu, H.1    Zhou, J.2    Wong, B.H.Y.3    Li, C.4    Chan, J.F.W.5    Cheng, Z.-S.6    Yuen, K.Y.7
  • 12
    • 77950806384 scopus 로고    scopus 로고
    • Deubiquitinating and interferon antagonism activities of coronavirus papain-like proteases
    • Clementz, M. A., Chen, Z., Banach, B. S., Wang, Y., Sun, L., Ratia, K., … Baker, S. C. (2010). Deubiquitinating and interferon antagonism activities of coronavirus papain-like proteases. Journal of Virology, 84(9), 4619–4629.
    • (2010) Journal of Virology , vol.84 , Issue.9 , pp. 4619-4629
    • Clementz, M.A.1    Chen, Z.2    Banach, B.S.3    Wang, Y.4    Sun, L.5    Ratia, K.6    Baker, S.C.7
  • 13
    • 84990252098 scopus 로고    scopus 로고
    • Abelson kinase inhibitors are potent inhibitors of severe acute respiratory syndrome coronavirus and Middle East respiratory syndrome coronavirus fusion
    • Coleman, C. M., Sisk, J. M., Mingo, R. M., Nelson, E. A., White, J. M., & Frieman, M. B. (2016). Abelson kinase inhibitors are potent inhibitors of severe acute respiratory syndrome coronavirus and Middle East respiratory syndrome coronavirus fusion. Journal of Virology, 90(19), 8924–8933.
    • (2016) Journal of Virology , vol.90 , Issue.19 , pp. 8924-8933
    • Coleman, C.M.1    Sisk, J.M.2    Mingo, R.M.3    Nelson, E.A.4    White, J.M.5    Frieman, M.B.6
  • 14
    • 84906968870 scopus 로고    scopus 로고
    • Rooting the phylogenetic tree of Middle East respiratory syndrome coronavirus by characterization of a conspecific virus from an African bat
    • Corman, V. M., Ithete, N. L., Richards, L. R., Schoeman, M. C., Preiser, W., Drosten, C., & Drexler, J. F. (2014). Rooting the phylogenetic tree of Middle East respiratory syndrome coronavirus by characterization of a conspecific virus from an African bat. Journal of Virology, 88(19), 11297–11303.
    • (2014) Journal of Virology , vol.88 , Issue.19 , pp. 11297-11303
    • Corman, V.M.1    Ithete, N.L.2    Richards, L.R.3    Schoeman, M.C.4    Preiser, W.5    Drosten, C.6    Drexler, J.F.7
  • 17
    • 85016626167 scopus 로고    scopus 로고
    • Middle East respiratory syndrome coronavirus: Transmission, virology and therapeutic targeting to aid in outbreak control
    • Durai, P., Batool, M., Shah, M., & Choi, S. (2015). Middle East respiratory syndrome coronavirus: Transmission, virology and therapeutic targeting to aid in outbreak control. Experimental & Molecular Medicine, 47(8), e181.
    • (2015) Experimental & Molecular Medicine , vol.47 , Issue.8
    • Durai, P.1    Batool, M.2    Shah, M.3    Choi, S.4
  • 18
    • 84895823870 scopus 로고    scopus 로고
    • Distinct immune response in two MERS-CoV-infected patients: Can we go from bench to bedside?
    • Faure, E., Poissy, J., Goffard, A., Fournier, C., Kipnis, E., Titecat, M., … Guery, B. (2014). Distinct immune response in two MERS-CoV-infected patients: Can we go from bench to bedside? PLoS One, 9(2), e88716.
    • (2014) PLoS One , vol.9 , Issue.2
    • Faure, E.1    Poissy, J.2    Goffard, A.3    Fournier, C.4    Kipnis, E.5    Titecat, M.6    Guery, B.7
  • 19
    • 85052366063 scopus 로고    scopus 로고
    • Evasion of host innate immunity by emerging viruses: Antagonizing host RIG-I pathways
    • Ferran, M. C., & Skuse, G. R. (2017). Evasion of host innate immunity by emerging viruses: Antagonizing host RIG-I pathways. J Emerg Dis Virol, 3(3).
    • (2017) J Emerg Dis Virol , vol.3 , Issue.3
    • Ferran, M.C.1    Skuse, G.R.2
  • 22
    • 84878173821 scopus 로고    scopus 로고
    • Cytosolic sensing of viruses
    • Goubau, D., Deddouche, S., & Reis e Sousa, C. (2013). Cytosolic sensing of viruses. Immunity, 38(5), 855–869.
    • (2013) Immunity , vol.38 , Issue.5 , pp. 855-869
    • Goubau, D.1    Deddouche, S.2    Reis e Sousa, C.3
  • 23
    • 84878966726 scopus 로고    scopus 로고
    • Middle East respiratory syndrome coronavirus (MERS-CoV): Announcement of the coronavirus study group
    • de Groot, R. J., Baker, S. C., Baric, R. S., Brown, C. S., Drosten, C., Enjuanes, L., … Ziebuhr, J. (2013). Middle East respiratory syndrome coronavirus (MERS-CoV): Announcement of the coronavirus study group. Journal of Virology, 87(14), 7790–7792.
    • (2013) Journal of Virology , vol.87 , Issue.14 , pp. 7790-7792
    • de Groot, R.J.1    Baker, S.C.2    Baric, R.S.3    Brown, C.S.4    Drosten, C.5    Enjuanes, L.6    Ziebuhr, J.7
  • 24
    • 34249058290 scopus 로고    scopus 로고
    • Modulation of the interferon antiviral response by the TBK1/IKKi adaptor protein TANK
    • Guo, B., & Cheng, G. (2007). Modulation of the interferon antiviral response by the TBK1/IKKi adaptor protein TANK. Journal of Biological Chemistry, 282(16), 11817–11826.
    • (2007) Journal of Biological Chemistry , vol.282 , Issue.16 , pp. 11817-11826
    • Guo, B.1    Cheng, G.2
  • 26
    • 0036343241 scopus 로고    scopus 로고
    • The group-specific murine coronavirus genes are not essential, but their deletion, by reverse genetics, is attenuating in the natural host
    • de Haan, C. A. M., Masters, P. S., Shen, X., Weiss, S., & Rottier, P. J. M. (2002). The group-specific murine coronavirus genes are not essential, but their deletion, by reverse genetics, is attenuating in the natural host. Virology, 296(1), 177–189.
    • (2002) Virology , vol.296 , Issue.1 , pp. 177-189
    • de Haan, C.A.M.1    Masters, P.S.2    Shen, X.3    Weiss, S.4    Rottier, P.J.M.5
  • 27
    • 1842432528 scopus 로고    scopus 로고
    • Live, attenuated coronavirus vaccines through the directed deletion of group-specific genes provide protection against feline infectious peritonitis
    • Haijema, B. J., Volders, H., & Rottier, P. J. M. (2004). Live, attenuated coronavirus vaccines through the directed deletion of group-specific genes provide protection against feline infectious peritonitis. Journal of Virology, 78(8), 3863–3871.
    • (2004) Journal of Virology , vol.78 , Issue.8 , pp. 3863-3871
    • Haijema, B.J.1    Volders, H.2    Rottier, P.J.M.3
  • 28
    • 34447499052 scopus 로고    scopus 로고
    • Triggering the innate antiviral response through IRF-3 activation
    • Hiscott, J. (2007). Triggering the innate antiviral response through IRF-3 activation. Journal of Biological Chemistry, 282(21), 15325–15329.
    • (2007) Journal of Biological Chemistry , vol.282 , Issue.21 , pp. 15325-15329
    • Hiscott, J.1
  • 29
    • 84879571351 scopus 로고    scopus 로고
    • Cell host response to infection with novel human coronavirus EMC predicts potential antivirals and important differences with SARS coronavirus
    • Josset, L., Menachery, V. D., Gralinski, L. E., Agnihothram, S., Sova, P., Carter, V. S., … Katze, M. G. (2013). Cell host response to infection with novel human coronavirus EMC predicts potential antivirals and important differences with SARS coronavirus. mBio, 4(3), e00165–00113.
    • (2013) mBio , vol.4 , Issue.3 , pp. e00113-e00165
    • Josset, L.1    Menachery, V.D.2    Gralinski, L.E.3    Agnihothram, S.4    Sova, P.5    Carter, V.S.6    Katze, M.G.7
  • 30
    • 85031929695 scopus 로고    scopus 로고
    • Human coronavirus-HKU1 infection among adults in Cleveland, Ohio
    • Kanwar, A., Selvaraju, S., & Esper, F. (2017). Human coronavirus-HKU1 infection among adults in Cleveland, Ohio. Open Forum Infectious Diseases, 4(2), ofx052.
    • (2017) Open Forum Infectious Diseases , vol.4 , Issue.2 , pp. ofx052
    • Kanwar, A.1    Selvaraju, S.2    Esper, F.3
  • 31
    • 33745298519 scopus 로고    scopus 로고
    • Nuclear factor-κB in cancer development and progression
    • Karin, M. (2006). Nuclear factor-κB in cancer development and progression. Nature, 441(7092), 431–436.
    • (2006) Nature , vol.441 , Issue.7092 , pp. 431-436
    • Karin, M.1
  • 32
    • 80052143412 scopus 로고    scopus 로고
    • RIG-I-like receptors: Cytoplasmic sensors for non-self RNA
    • Kato, H., Takahasi, K., & Fujita, T. (2011). RIG-I-like receptors: Cytoplasmic sensors for non-self RNA. Immunological Reviews, 243(1), 91–98.
    • (2011) Immunological Reviews , vol.243 , Issue.1 , pp. 91-98
    • Kato, H.1    Takahasi, K.2    Fujita, T.3
  • 33
    • 84995442519 scopus 로고    scopus 로고
    • Clinical progression and cytokine profiles of Middle East respiratory syndrome coronavirus infection
    • Kim, E. S., Choe, P. G., Park, W. B., Oh, H. S., Kim, E. J., Nam, E. Y., … Oh, M. (2016). Clinical progression and cytokine profiles of Middle East respiratory syndrome coronavirus infection. Journal of Korean Medical Science, 31(11), 1717–1725.
    • (2016) Journal of Korean Medical Science , vol.31 , Issue.11 , pp. 1717-1725
    • Kim, E.S.1    Choe, P.G.2    Park, W.B.3    Oh, H.S.4    Kim, E.J.5    Nam, E.Y.6    Oh, M.7
  • 34
    • 84901999946 scopus 로고    scopus 로고
    • To sense or not to sense viral RNA—Essentials of coronavirus innate immune evasion
    • [Supplement C].
    • Kindler, E., & Thiel, V. (2014). To sense or not to sense viral RNA—Essentials of coronavirus innate immune evasion. Current Opinion in Microbiology, 20, 69–75. [Supplement C].
    • (2014) Current Opinion in Microbiology , vol.20 , pp. 69-75
    • Kindler, E.1    Thiel, V.2
  • 35
    • 79955075657 scopus 로고    scopus 로고
    • The double-stranded RNA-binding protein PACT functions as a cellular activator of RIG-I to facilitate innate antiviral response
    • Kok, K.-H., Lui, P.-Y., Ng, M. H., Siu, K.-L., Au, S. W., & Jin, D.-Y. (2011). The double-stranded RNA-binding protein PACT functions as a cellular activator of RIG-I to facilitate innate antiviral response. Cell Host and Microbe, 9(4), 299–309.
    • (2011) Cell Host and Microbe , vol.9 , Issue.4 , pp. 299-309
    • Kok, K.-H.1    Lui, P.-Y.2    Ng, M.H.3    Siu, K.-L.4    Au, S.W.5    Jin, D.-Y.6
  • 36
    • 84880593983 scopus 로고    scopus 로고
    • Genetic characterization of Betacoronavirus lineage C viruses in bats reveals marked sequence divergence in the spike protein of pipistrellus bat coronavirus HKU5 in Japanese pipistrelle: Implications for the origin of the novel Middle East respiratory syndrome coronavirus
    • Lau, S. K., Li, K. S., Tsang, A. K., Lam, C. S., Ahmed, S., Chen, H., … Yuen, K.-Y. (2013). Genetic characterization of Betacoronavirus lineage C viruses in bats reveals marked sequence divergence in the spike protein of pipistrellus bat coronavirus HKU5 in Japanese pipistrelle: Implications for the origin of the novel Middle East respiratory syndrome coronavirus. Journal of Virology, 87(15), 8638–8650.
    • (2013) Journal of Virology , vol.87 , Issue.15 , pp. 8638-8650
    • Lau, S.K.1    Li, K.S.2    Tsang, A.K.3    Lam, C.S.4    Ahmed, S.5    Chen, H.6    Yuen, K.-Y.7
  • 37
    • 77957596318 scopus 로고    scopus 로고
    • Immune evasion by Kaposi’s sarcoma-associated herpesvirus
    • Lee, H.-R., Lee, S., Chaudhary, P. M., Gill, P., & Jung, J. U. (2010). Immune evasion by Kaposi’s sarcoma-associated herpesvirus. Future Microbiology, 5(9), 1349–1365.
    • (2010) Future Microbiology , vol.5 , Issue.9 , pp. 1349-1365
    • Lee, H.-R.1    Lee, S.2    Chaudhary, P.M.3    Gill, P.4    Jung, J.U.5
  • 38
    • 84904545615 scopus 로고    scopus 로고
    • Accessory proteins of SARS-CoV and other coronaviruses
    • [Supplement C].
    • Liu, D. X., Fung, T. S., Chong, K. K.-L., Shukla, A., & Hilgenfeld, R. (2014). Accessory proteins of SARS-CoV and other coronaviruses. Antiviral Research, 109, 97–109. [Supplement C].
    • (2014) Antiviral Research , vol.109 , pp. 97-109
    • Liu, D.X.1    Fung, T.S.2    Chong, K.K.L.3    Shukla, A.4    Hilgenfeld, R.5
  • 40
    • 84881479703 scopus 로고    scopus 로고
    • Molecular basis of binding between novel human coronavirus MERS-CoV and its receptor CD26
    • Lu, G., Hu, Y., Wang, Q., Qi, J., Gao, F., Li, Y., … Gao, G. F. (2013). Molecular basis of binding between novel human coronavirus MERS-CoV and its receptor CD26. Nature, 500(7461), 227–231.
    • (2013) Nature , vol.500 , Issue.7461 , pp. 227-231
    • Lu, G.1    Hu, Y.2    Wang, Q.3    Qi, J.4    Gao, F.5    Li, Y.6    Gao, G.F.7
  • 41
    • 85003938202 scopus 로고    scopus 로고
    • Middle East respiratory syndrome coronavirus M protein suppresses type I interferon expression through the inhibition of TBK1-dependent phosphorylation of IRF3
    • Lui, P.-Y., Wong, L. Y., Fung, C.-L., Siu, K.-L., Yeung, M.-L., Yuen, K.-S., … Jin, D.-Y. (2016). Middle East respiratory syndrome coronavirus M protein suppresses type I interferon expression through the inhibition of TBK1-dependent phosphorylation of IRF3. Emerging Microbes & Infections, 5(4), e39.
    • (2016) Emerging Microbes & Infections , vol.5 , Issue.4
    • Lui, P.-Y.1    Wong, L.Y.2    Fung, C.-L.3    Siu, K.-L.4    Yeung, M.-L.5    Yuen, K.-S.6    Jin, D.-Y.7
  • 42
    • 84897055458 scopus 로고    scopus 로고
    • The ORF4b-encoded accessory proteins of Middle East respiratory syndrome coronavirus and two related bat coronaviruses localize to the nucleus and inhibit innate immune signalling
    • Matthews, K. L., Coleman, C. M., van der Meer, Y., Snijder, E. J., & Frieman, M. B. (2014). The ORF4b-encoded accessory proteins of Middle East respiratory syndrome coronavirus and two related bat coronaviruses localize to the nucleus and inhibit innate immune signalling. The Journal of General Virology, 95(Pt 4), 874–882.
    • (2014) The Journal of General Virology , vol.95 , pp. 874-882
    • Matthews, K.L.1    Coleman, C.M.2    van der Meer, Y.3    Snijder, E.J.4    Frieman, M.B.5
  • 43
    • 84890863276 scopus 로고    scopus 로고
    • MERS-CoV papain-like protease has deISGylating and deubiquitinating activities
    • Mielech, A. M., Kilianski, A., Baez-Santos, Y. M., Mesecar, A. D., & Baker, S. C. (2014). MERS-CoV papain-like protease has deISGylating and deubiquitinating activities. Virology, 450-451, 64–70.
    • (2014) Virology , vol.450-451 , pp. 64-70
    • Mielech, A.M.1    Kilianski, A.2    Baez-Santos, Y.M.3    Mesecar, A.D.4    Baker, S.C.5
  • 44
    • 85057939203 scopus 로고    scopus 로고
    • The receptor binding domain of the new MERS coronavirus maps to a 231-residue region in the spike protein that efficiently elicits neutralizing antibodies
    • Mou, H., Raj, V. S., van Kuppeveld, F. J., Rottier, P. J., Haagmans, B. L., & Bosch, B. J. (2013). The receptor binding domain of the new MERS coronavirus maps to a 231-residue region in the spike protein that efficiently elicits neutralizing antibodies. Journal of Virology, 87, 01277–01213.
    • (2013) Journal of Virology , vol.87 , pp. 01213-01277
    • Mou, H.1    Raj, V.S.2    van Kuppeveld, F.J.3    Rottier, P.J.4    Haagmans, B.L.5    Bosch, B.J.6
  • 45
    • 85028465604 scopus 로고    scopus 로고
    • Current treatment options and the role of peptides as potential therapeutic components for Middle East Respiratory Syndrome (MERS): A review
    • Mustafa, S., Balkhy, H., & Gabere, M. N. (2017). Current treatment options and the role of peptides as potential therapeutic components for Middle East Respiratory Syndrome (MERS): A review. Journal of Infection and Public Health, 11, 9–17.
    • (2017) Journal of Infection and Public Health , vol.11 , pp. 9-17
    • Mustafa, S.1    Balkhy, H.2    Gabere, M.N.3
  • 47
    • 85013428035 scopus 로고    scopus 로고
    • The immune system
    • Nicholson, L. B. (2016). The immune system. Essays in Biochemistry, 60(3), 275–301.
    • (2016) Essays in Biochemistry , vol.60 , Issue.3 , pp. 275-301
    • Nicholson, L.B.1
  • 48
    • 84886298565 scopus 로고    scopus 로고
    • Middle East respiratory syndrome coronavirus accessory protein 4a Is a Type I interferon antagonist
    • Niemeyer, D., Zillinger, T., Muth, D., Zielecki, F., Horvath, G., Suliman, T., … Muller, M. A. (2013). Middle East respiratory syndrome coronavirus accessory protein 4a Is a Type I interferon antagonist. Journal of Virology, 87(22), 12489–12495.
    • (2013) Journal of Virology , vol.87 , Issue.22 , pp. 12489-12495
    • Niemeyer, D.1    Zillinger, T.2    Muth, D.3    Zielecki, F.4    Horvath, G.5    Suliman, T.6    Muller, M.A.7
  • 49
    • 84888037046 scopus 로고    scopus 로고
    • Inhibition of Middle East respiratory syndrome coronavirus infection by anti-CD26 monoclonal antibody
    • Ohnuma, K., Haagmans, B. L., Hatano, R., Raj, V. S., Mou, H., Iwata, S., … Morimoto, C. (2013). Inhibition of Middle East respiratory syndrome coronavirus infection by anti-CD26 monoclonal antibody. Journal of Virology, 87(24), 13892–13899.
    • (2013) Journal of Virology , vol.87 , Issue.24 , pp. 13892-13899
    • Ohnuma, K.1    Haagmans, B.L.2    Hatano, R.3    Raj, V.S.4    Mou, H.5    Iwata, S.6    Morimoto, C.7
  • 51
    • 79960115481 scopus 로고    scopus 로고
    • The Role of nuclear factor κB in the interferon response
    • Pfeffer, L. M. (2011). The Role of nuclear factor κB in the interferon response. Journal of Interferon & Cytokine Research, 31(7), 553–559.
    • (2011) Journal of Interferon & Cytokine Research , vol.31 , Issue.7 , pp. 553-559
    • Pfeffer, L.M.1
  • 53
    • 84874996988 scopus 로고    scopus 로고
    • Dipeptidyl peptidase 4 is a functional receptor for the emerging human coronavirus-EMC
    • Raj, V. S., Mou, H., Smits, S. L., Dekkers, D. H. W., Müller, M. A., Dijkman, R., … Haagmans, B. L. (2013). Dipeptidyl peptidase 4 is a functional receptor for the emerging human coronavirus-EMC. Nature, 495(7440), 251–254.
    • (2013) Nature , vol.495 , Issue.7440 , pp. 251-254
    • Raj, V.S.1    Mou, H.2    Smits, S.L.3    Dekkers, D.H.W.4    Müller, M.A.5    Dijkman, R.6    Haagmans, B.L.7
  • 54
    • 84892463403 scopus 로고    scopus 로고
    • Adenosine deaminase acts as a natural antagonist for dipeptidyl peptidase 4-mediated entry of the Middle East respiratory syndrome coronavirus
    • Raj, V. S., Smits, S. L., Provacia, L. B., van den Brand, J. M. A., Wiersma, L., Ouwendijk, W. J. D., … Haagmans, B. L. (2014). Adenosine deaminase acts as a natural antagonist for dipeptidyl peptidase 4-mediated entry of the Middle East respiratory syndrome coronavirus. Journal of Virology, 88(3), 1834–1838.
    • (2014) Journal of Virology , vol.88 , Issue.3 , pp. 1834-1838
    • Raj, V.S.1    Smits, S.L.2    Provacia, L.B.3    van den Brand, J.M.A.4    Wiersma, L.5    Ouwendijk, W.J.D.6    Haagmans, B.L.7
  • 55
    • 24144461689 scopus 로고    scopus 로고
    • Identification and characterization of MAVS, a mitochondrial antiviral signaling protein that activates NF-κB and IRF3
    • Seth, R. B., Sun, L., Ea, C.-K., & Chen, Z. J. (2005). Identification and characterization of MAVS, a mitochondrial antiviral signaling protein that activates NF-κB and IRF3. Cell, 122(5), 669–682.
    • (2005) Cell , vol.122 , Issue.5 , pp. 669-682
    • Seth, R.B.1    Sun, L.2    Ea, C.-K.3    Chen, Z.J.4
  • 57
    • 84895546659 scopus 로고    scopus 로고
    • Suppression of innate antiviral response by severe acute respiratory syndrome coronavirus M protein is mediated through the first transmembrane domain
    • Siu, K.-L., Chan, C.-P., Kok, K.-H., Chiu-Yat Woo, P., & Jin, D.-Y. (2014). Suppression of innate antiviral response by severe acute respiratory syndrome coronavirus M protein is mediated through the first transmembrane domain. Cellular and Molecular Immunology, 11(2), 141–149.
    • (2014) Cellular and Molecular Immunology , vol.11 , Issue.2 , pp. 141-149
    • Siu, K.-L.1    Chan, C.-P.2    Kok, K.-H.3    Chiu-Yat Woo, P.4    Jin, D.-Y.5
  • 58
    • 67650230347 scopus 로고    scopus 로고
    • Severe acute respiratory syndrome coronavirus M protein inhibits type I interferon production by impeding the formation of TRAF3·TANK·TBK1/IKKϵ Complex
    • Siu, K.-L., Kok, K.-H., Ng, M.-H. J., Poon, V. K. M., Yuen, K.-Y., Zheng, B.-J., & Jin, D.-Y. (2009). Severe acute respiratory syndrome coronavirus M protein inhibits type I interferon production by impeding the formation of TRAF3·TANK·TBK1/IKKϵ Complex. The Journal of Biological Chemistry, 284(24), 16202–16209.
    • (2009) The Journal of Biological Chemistry , vol.284 , Issue.24 , pp. 16202-16209
    • Siu, K.-L.1    Kok, K.-H.2    Ng, M.H.J.3    Poon, V.K.M.4    Yuen, K.-Y.5    Zheng, B.-J.6    Jin, D.-Y.7
  • 59
    • 84895534920 scopus 로고    scopus 로고
    • Middle East respiratory syndrome coronavirus 4a protein is a double-stranded RNA-binding protein that suppresses PACT-induced activation of RIG-I and MDA5 in the innate antiviral response
    • Siu, K.-L., Yeung, M. L., Kok, K.-H., Yuen, K.-S., Kew, C., Lui, P.-Y., … Jin, D.-Y. (2014). Middle East respiratory syndrome coronavirus 4a protein is a double-stranded RNA-binding protein that suppresses PACT-induced activation of RIG-I and MDA5 in the innate antiviral response. Journal of Virology, 88(9), 4866–4876.
    • (2014) Journal of Virology , vol.88 , Issue.9 , pp. 4866-4876
    • Siu, K.-L.1    Yeung, M.L.2    Kok, K.-H.3    Yuen, K.-S.4    Kew, C.5    Lui, P.-Y.6    Jin, D.-Y.7
  • 60
    • 0037151040 scopus 로고    scopus 로고
    • Direct involvement of CREB-binding protein/p300 in sequence-specific DNA binding of virus-activated interferon regulatory factor-3 holocomplex
    • Suhara, W., Yoneyama, M., Kitabayashi, I., & Fujita, T. (2002). Direct involvement of CREB-binding protein/p300 in sequence-specific DNA binding of virus-activated interferon regulatory factor-3 holocomplex. Journal of Biological Chemistry, 277(25), 22304–22313.
    • (2002) Journal of Biological Chemistry , vol.277 , Issue.25 , pp. 22304-22313
    • Suhara, W.1    Yoneyama, M.2    Kitabayashi, I.3    Fujita, T.4
  • 61
    • 13944253573 scopus 로고    scopus 로고
    • Regulating intracellular antiviral defense and permissiveness to hepatitis C virus RNA replication through a cellular RNA helicase, RIG-I
    • Sumpter, R., Loo, Y.-M., Foy, E., Li, K., Yoneyama, M., Fujita, T., … Gale, M. (2005). Regulating intracellular antiviral defense and permissiveness to hepatitis C virus RNA replication through a cellular RNA helicase, RIG-I. Journal of Virology, 79(5), 2689–2699.
    • (2005) Journal of Virology , vol.79 , Issue.5 , pp. 2689-2699
    • Sumpter, R.1    Loo, Y.-M.2    Foy, E.3    Li, K.4    Yoneyama, M.5    Fujita, T.6    Gale, M.7
  • 62
    • 58049202272 scopus 로고    scopus 로고
    • Innate immunity to virus infection
    • Takeuchi, O., & Akira, S. (2009). Innate immunity to virus infection. Immunological Reviews, 227(1), 75–86.
    • (2009) Immunological Reviews , vol.227 , Issue.1 , pp. 75-86
    • Takeuchi, O.1    Akira, S.2
  • 63
    • 84965112401 scopus 로고    scopus 로고
    • Middle East respiratory syndrome coronavirus NS4b protein inhibits host RNase L activation
    • Thornbrough, J. M., Jha, B. K., Yount, B., Goldstein, S. A., Li, Y., Elliott, R., … Weiss, S. R. (2016). Middle East respiratory syndrome coronavirus NS4b protein inhibits host RNase L activation. mBio, 7(2), e00258–00216.
    • (2016) mBio , vol.7 , Issue.2 , pp. e00216-e00258
    • Thornbrough, J.M.1    Jha, B.K.2    Yount, B.3    Goldstein, S.A.4    Li, Y.5    Elliott, R.6    Weiss, S.R.7
  • 64
    • 84862895252 scopus 로고    scopus 로고
    • SARS coronavirus pathogenesis: Host innate immune responses and viral antagonism of interferon
    • Totura, A. L., & Baric, R. S. (2012). SARS coronavirus pathogenesis: Host innate immune responses and viral antagonism of interferon. Current Opinion in Virology, 2(3), 264–275.
    • (2012) Current Opinion in Virology , vol.2 , Issue.3 , pp. 264-275
    • Totura, A.L.1    Baric, R.S.2
  • 67
    • 84959187921 scopus 로고    scopus 로고
    • A molecular arms race between host innate antiviral response and emerging human coronaviruses
    • Wong, L.-Y. R., Lui, P.-Y., & Jin, D.-Y. (2016). A molecular arms race between host innate antiviral response and emerging human coronaviruses. Virologica Sinica, 31(1), 12–23.
    • (2016) Virologica Sinica , vol.31 , Issue.1 , pp. 12-23
    • Wong, L.Y.R.1    Lui, P.-Y.2    Jin, D.-Y.3
  • 68
    • 84894076838 scopus 로고    scopus 로고
    • Proteolytic processing, deubiquitinase and interferon antagonist activities of Middle East respiratory syndrome coronavirus papain-like protease
    • Yang, X., Chen, X., Bian, G., Tu, J., Xing, Y., Wang, Y., & Chen, Z. (2014). Proteolytic processing, deubiquitinase and interferon antagonist activities of Middle East respiratory syndrome coronavirus papain-like protease. Journal of General Virology, 95(3), 614–626.
    • (2014) Journal of General Virology , vol.95 , Issue.3 , pp. 614-626
    • Yang, X.1    Chen, X.2    Bian, G.3    Tu, J.4    Xing, Y.5    Wang, Y.6    Chen, Z.7
  • 69
    • 84890049888 scopus 로고    scopus 로고
    • The structural and accessory proteins M, ORF 4a, ORF 4b, and ORF 5 of Middle East respiratory syndrome coronavirus (MERS-CoV) are potent interferon antagonists
    • Yang, Y., Zhang, L., Geng, H., Deng, Y., Huang, B., Guo, Y., … Tan, W. (2013). The structural and accessory proteins M, ORF 4a, ORF 4b, and ORF 5 of Middle East respiratory syndrome coronavirus (MERS-CoV) are potent interferon antagonists. Protein & Cell, 4(12), 951–961.
    • (2013) Protein & Cell , vol.4 , Issue.12 , pp. 951-961
    • Yang, Y.1    Zhang, L.2    Geng, H.3    Deng, Y.4    Huang, B.5    Guo, Y.6    Tan, W.7
  • 70
    • 84964879131 scopus 로고    scopus 로고
    • Discovery of T-cell infection and apoptosis by Middle East respiratory syndrome coronavirus
    • Ying, T., Li, W., & Dimitrov, D. S. (2016). Discovery of T-cell infection and apoptosis by Middle East respiratory syndrome coronavirus. The Journal of Infectious Diseases, 213(6), 877–879.
    • (2016) The Journal of Infectious Diseases , vol.213 , Issue.6 , pp. 877-879
    • Ying, T.1    Li, W.2    Dimitrov, D.S.3
  • 71
    • 3242813113 scopus 로고    scopus 로고
    • The RNA helicase RIG-I has an essential function in double-stranded RNA-induced innate antiviral responses
    • Yoneyama, M., Kikuchi, M., Natsukawa, T., Shinobu, N., Imaizumi, T., Miyagishi, M., … Fujita, T. (2004). The RNA helicase RIG-I has an essential function in double-stranded RNA-induced innate antiviral responses. Nature Immunology, 5(7), 730–737.
    • (2004) Nature Immunology , vol.5 , Issue.7 , pp. 730-737
    • Yoneyama, M.1    Kikuchi, M.2    Natsukawa, T.3    Shinobu, N.4    Imaizumi, T.5    Miyagishi, M.6    Fujita, T.7
  • 72
    • 84901003129 scopus 로고    scopus 로고
    • Current advancements and potential strategies in the development of MERS-CoV vaccines
    • Zhang, N., Jiang, S., & Du, L. (2014). Current advancements and potential strategies in the development of MERS-CoV vaccines. Expert Review of Vaccines, 13(6), 761–774.
    • (2014) Expert Review of Vaccines , vol.13 , Issue.6 , pp. 761-774
    • Zhang, N.1    Jiang, S.2    Du, L.3
  • 74
    • 84862297105 scopus 로고    scopus 로고
    • Antagonism of the interferon-induced OAS-RNase L pathway by murine coronavirus ns2 protein is required for virus replication and liver pathology
    • Zhao, L., Jha, B. K., Wu, A., Elliott, R., Ziebuhr, J., Gorbalenya, A. E., … Weiss, S. R. (2012). Antagonism of the interferon-induced OAS-RNase L pathway by murine coronavirus ns2 protein is required for virus replication and liver pathology. Cell Host and Microbe, 11(6), 607–616.
    • (2012) Cell Host and Microbe , vol.11 , Issue.6 , pp. 607-616
    • Zhao, L.1    Jha, B.K.2    Wu, A.3    Elliott, R.4    Ziebuhr, J.5    Gorbalenya, A.E.6    Weiss, S.R.7
  • 75
    • 84955365655 scopus 로고    scopus 로고
    • Middle East respiratory syndrome coronavirus infection: Virus-host cell interactions and implications on pathogenesis
    • Zhou, J., Chu, H., Chan, J. F.-W., & Yuen, K.-Y. (2015). Middle East respiratory syndrome coronavirus infection: Virus-host cell interactions and implications on pathogenesis. Virology Journal, 12(1), 218.
    • (2015) Virology Journal , vol.12 , Issue.1 , pp. 218
    • Zhou, J.1    Chu, H.2    Chan, J.F.W.3    Yuen, K.-Y.4
  • 76
    • 84898850857 scopus 로고    scopus 로고
    • Active replication of Middle East respiratory syndrome coronavirus and aberrant induction of inflammatory cytokines and chemokines in human macrophages: Implications for pathogenesis
    • Zhou, J., Chu, H., Li, C., Wong, B. H.-Y., Cheng, Z.-S., Poon, V. K.-M., … Yuen, K.-Y. (2014). Active replication of Middle East respiratory syndrome coronavirus and aberrant induction of inflammatory cytokines and chemokines in human macrophages: Implications for pathogenesis. The Journal of Infectious Diseases, 209(9), 1331–1342.
    • (2014) The Journal of Infectious Diseases , vol.209 , Issue.9 , pp. 1331-1342
    • Zhou, J.1    Chu, H.2    Li, C.3    Wong, B.H.Y.4    Cheng, Z.-S.5    Poon, V.K.M.6    Yuen, K.-Y.7
  • 77
    • 84941413167 scopus 로고    scopus 로고
    • Middle East respiratory syndrome
    • Zumla, A., Hui, D. S., & Perlman, S. (2015). Middle East respiratory syndrome. The Lancet, 386(9997), 995–1007.
    • (2015) The Lancet , vol.386 , Issue.9997 , pp. 995-1007
    • Zumla, A.1    Hui, D.S.2    Perlman, S.3


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