-
1
-
-
84907980044
-
Catalytic function and substrate specificity of the papain-like protease domain of nsp3 from the Middle East respiratory syndrome coronavirus
-
Baez-Santos YM, Mielech AM, Deng X, Baker S, Mesecar AD. Catalytic function and substrate specificity of the papain-like protease domain of nsp3 from the Middle East respiratory syndrome coronavirus. J Virol 2014; 88: 12511–12527.
-
(2014)
J Virol
, vol.88
, pp. 12511-12527
-
-
Baez-Santos, Y.M.1
Mielech, A.M.2
Deng, X.3
Baker, S.4
Mesecar, A.D.5
-
2
-
-
84939466737
-
Middle East Respiratory Syndrome Coronavirus ‘MERS-CoV’: Current knowledge gaps
-
Banik GR, Khandaker G, Rashid H. Middle East Respiratory Syndrome Coronavirus ‘MERS-CoV’: current knowledge gaps. Paediatr Respir Rev 2015; 16: 197–202.
-
(2015)
Paediatr Respir Rev
, vol.16
, pp. 197-202
-
-
Banik, G.R.1
Khandaker, G.2
Rashid, H.3
-
3
-
-
84928206646
-
A more detailed picture of the epidemiology of Middle East respiratory syndrome coronavirus
-
Kayali G, Peiris M. A more detailed picture of the epidemiology of Middle East respiratory syndrome coronavirus. Lancet Infect Dis 2015; 15: 495–497.
-
(2015)
Lancet Infect Dis
, vol.15
, pp. 495-497
-
-
Kayali, G.1
Peiris, M.2
-
4
-
-
84868516062
-
Isolation of a novel coronavirus from a man with pneumonia in Saudi Arabia
-
Zaki AM, van Boheemen S, Bestebroer TM, Osterhaus AD, Fouchier RA. Isolation of a novel coronavirus from a man with pneumonia in Saudi Arabia. NEnglJMed2012; 367: 1814–1820.
-
(2012)
Nengljmed
, vol.367
, pp. 1814-1820
-
-
Zaki, A.M.1
van Boheemen, S.2
Bestebroer, T.M.3
Osterhaus, A.D.4
Fouchier, R.A.5
-
5
-
-
84902811628
-
The emergence of the Middle East respiratory syndrome coronavirus
-
Milne-Price S, Miazgowicz KL, Munster VJ. The emergence of the Middle East respiratory syndrome coronavirus. Pathog Dis 2014; 71: 121–136.
-
(2014)
Pathog Dis
, vol.71
, pp. 121-136
-
-
Milne-Price, S.1
Miazgowicz, K.L.2
Munster, V.J.3
-
6
-
-
84908485680
-
Middle East respiratory syndrome coronavirus: Transmission and phylogenetic evolution
-
Al-Tawfiq JA, Memish ZA. Middle East respiratory syndrome coronavirus: transmission and phylogenetic evolution. Trends Microbiol 2014; 22: 573–579.
-
(2014)
Trends Microbiol
, vol.22
, pp. 573-579
-
-
Al-Tawfiq, J.A.1
Memish, Z.A.2
-
7
-
-
19944427959
-
Characterization and complete genome sequence of a novel coronavirus, coronavirus HKU1, from patients with pneumonia
-
Woo PC, Lau SK, Chu CM, Chan KH, Tsoi HW, Huang Y et al. Characterization and complete genome sequence of a novel coronavirus, coronavirus HKU1, from patients with pneumonia. J Virol 2005; 79: 884–895.
-
(2005)
J Virol
, vol.79
, pp. 884-895
-
-
Woo, P.C.1
Lau, S.K.2
Chu, C.M.3
Chan, K.H.4
Tsoi, H.W.5
Huang, Y.6
-
8
-
-
33644820689
-
History and recent advances in coronavirus discovery
-
discussion S226
-
Kahn JS, McIntosh K. History and recent advances in coronavirus discovery. Pediatr Infect Dis J 2005; 24: S223–S227, discussion S226.
-
(2005)
Pediatr Infect Dis J
, vol.24
, pp. S223-S227
-
-
Kahn, J.S.1
McIntosh, K.2
-
9
-
-
84935017499
-
Inhibitor recognition specificity of MERS-CoV papain-like protease may differ from that of SARS-CoV
-
Lee H, Lei H, Santarsiero BD, Gatuz JL, Cao S, Rice AJ et al. Inhibitor recognition specificity of MERS-CoV papain-like protease may differ from that of SARS-CoV. ACS Chem Biol 2015; 10: 1456–1465.
-
(2015)
ACS Chem Biol
, vol.10
, pp. 1456-1465
-
-
Lee, H.1
Lei, H.2
Santarsiero, B.D.3
Gatuz, J.L.4
Cao, S.5
Rice, A.J.6
-
10
-
-
67349158649
-
Coronaviruses post-SARS: Update on replication and pathogenesis
-
Perlman S, Netland J. Coronaviruses post-SARS: update on replication and pathogenesis. Nat Rev Microbiol 2009; 7: 439–450.
-
(2009)
Nat Rev Microbiol
, vol.7
, pp. 439-450
-
-
Perlman, S.1
Netland, J.2
-
12
-
-
84886258554
-
Emerging human middle East respiratory syndrome coronavirus causes widespread infection and alveolar damage in human lungs
-
Hocke AC, Becher A, Knepper J, Peter A, Holland G, Tonnies M et al. Emerging human middle East respiratory syndrome coronavirus causes widespread infection and alveolar damage in human lungs. Am J Respir Crit Care Med 2013; 188: 882–886.
-
(2013)
Am J Respir Crit Care Med
, vol.188
, pp. 882-886
-
-
Hocke, A.C.1
Becher, A.2
Knepper, J.3
Peter, A.4
Holland, G.5
Tonnies, M.6
-
13
-
-
84941413167
-
Middle East respiratory syndrome
-
in press
-
Zumla A, Hui DS, Perlman S. Middle East respiratory syndrome. Lancet 2015; doi:10.1016/S0140-6736(15)60454-8 (in press).
-
(2015)
Lancet
-
-
Zumla, A.1
Hui, D.S.2
Perlman, S.3
-
14
-
-
84900991538
-
Unraveling the mysteries of Middle East respiratory syndrome coronavirus
-
Watson JT, Hall AJ, Erdman DD, Swerdlow DL, Gerber SI. Unraveling the mysteries of Middle East respiratory syndrome coronavirus. Emerg Infect Dis 2014; 20: 1054–1056.
-
(2014)
Emerg Infect Dis
, vol.20
, pp. 1054-1056
-
-
Watson, J.T.1
Hall, A.J.2
Erdman, D.D.3
Swerdlow, D.L.4
Gerber, S.I.5
-
15
-
-
84930395004
-
Middle East respiratory syndrome coronavirus: Update for clinicians
-
Rasmussen SA, Gerber SI, Swerdlow DL. Middle East respiratory syndrome coronavirus: update for clinicians. Clin Infect Dis 2015; 60: 1686–1689.
-
(2015)
Clin Infect Dis
, vol.60
, pp. 1686-1689
-
-
Rasmussen, S.A.1
Gerber, S.I.2
Swerdlow, D.L.3
-
16
-
-
84901003129
-
Current advancements and potential strategies in the development of MERS-CoV vaccines
-
Zhang N, Jiang S, Du L. Current advancements and potential strategies in the development of MERS-CoV vaccines. Expert Rev Vaccines 2014; 13: 761–774.
-
(2014)
Expert Rev Vaccines
, vol.13
, pp. 761-774
-
-
Zhang, N.1
Jiang, S.2
Du, L.3
-
17
-
-
84939231634
-
Ligand-induced dimerization of MERS coronavirus nsp5 protease (3CLpro): Implications for nsp5 regulation and the development of antivirals
-
Tomar S, Johnston ML St, John SE, Osswald HL, Nyalapatla PR, Paul LN et al. Ligand-induced dimerization of MERS coronavirus nsp5 protease (3CLpro): implications for nsp5 regulation and the development of antivirals. JBiolChem2015; 290: 19403–19422.
-
(2015)
Jbiolchem
, vol.290
-
-
Tomar, S.1
St, J.M.L.2
John, S.E.3
Osswald, H.L.4
Nyalapatla, P.R.5
Paul, L.N.6
-
18
-
-
84918528852
-
Crystal structure of the Middle East respiratory syndrome coronavirus (MERS-CoV) papain-like protease bound to ubiquitin facilitates targeted disruption of deubiquitinating activity to demonstrate its role in innate immune suppression
-
Bailey-Elkin BA, Knaap RC, Johnson GG, Dalebout TJ, Ninaber DK, van Kasteren PB et al. Crystal structure of the Middle East respiratory syndrome coronavirus (MERS-CoV) papain-like protease bound to ubiquitin facilitates targeted disruption of deubiquitinating activity to demonstrate its role in innate immune suppression. J Biol Chem 2014; 289: 34667–34682.
-
(2014)
J Biol Chem
, vol.289
, pp. 34667-34682
-
-
Bailey-Elkin, B.A.1
Knaap, R.C.2
Johnson, G.G.3
Dalebout, T.J.4
Ninaber, D.K.5
van Kasteren, P.B.6
-
19
-
-
84894076838
-
Proteolytic processing, deubiquitinase and interferon antagonist activities of Middle East respiratory syndrome coronavirus papain-like protease
-
Yang X, Chen X, Bian G, Tu J, Xing Y, Wang Y et al. Proteolytic processing, deubiquitinase and interferon antagonist activities of Middle East respiratory syndrome coronavirus papain-like protease. J Gen Virol 2014; 95: 614–626.
-
(2014)
J Gen Virol
, vol.95
, pp. 614-626
-
-
Yang, X.1
Chen, X.2
Bian, G.3
Tu, J.4
Xing, Y.5
Wang, Y.6
-
20
-
-
84883438898
-
Coronaviruses lacking exoribonuclease activity are susceptible to lethal mutagenesis: Evidence for proofreading and potential therapeutics
-
Smith EC, Blanc H, Surdel MC, Vignuzzi M, Denison MR. Coronaviruses lacking exoribonuclease activity are susceptible to lethal mutagenesis: evidence for proofreading and potential therapeutics. PLoS Pathog 2013; 9: e1003565.
-
(2013)
Plos Pathog
, vol.9
-
-
Smith, E.C.1
Blanc, H.2
Surdel, M.C.3
Vignuzzi, M.4
Denison, M.R.5
-
21
-
-
84920649487
-
Middle East respiratory syndrome coronavirus (MERS-CoV) entry inhibitors targeting spike protein
-
Xia S, Liu Q, Wang Q, Sun Z, Su S, Du L et al. Middle East respiratory syndrome coronavirus (MERS-CoV) entry inhibitors targeting spike protein. Virus Res 2014; 194: 200–210.
-
(2014)
Virus Res
, vol.194
, pp. 200-210
-
-
Xia, S.1
Liu, Q.2
Wang, Q.3
Sun, Z.4
Su, S.5
Du, L.6
-
22
-
-
84881479703
-
Molecular basis of binding between novel human coronavirus MERS-CoV and its receptor CD26
-
Lu G, Hu Y, Wang Q, Qi J, Gao F, Li Y et al. Molecular basis of binding between novel human coronavirus MERS-CoV and its receptor CD26. Nature 2013; 500: 227–231.
-
(2013)
Nature
, vol.500
, pp. 227-231
-
-
Lu, G.1
Hu, Y.2
Wang, Q.3
Qi, J.4
Gao, F.5
Li, Y.6
-
23
-
-
0344395657
-
Angiotensin-converting enzyme 2 is a functional receptor for the SARS coronavirus
-
Li W, Moore MJ, Vasilieva N, Sui J, Wong SK, Berne MA et al. Angiotensin-converting enzyme 2 is a functional receptor for the SARS coronavirus. Nature 2003; 426: 450–454.
-
(2003)
Nature
, vol.426
, pp. 450-454
-
-
Li, W.1
Moore, M.J.2
Vasilieva, N.3
Sui, J.4
Wong, S.K.5
Berne, M.A.6
-
24
-
-
84888011629
-
A decade after SARS: Strategies for controlling emerging coronaviruses
-
Graham RL, Donaldson EF, Baric RS. A decade after SARS: strategies for controlling emerging coronaviruses. Nat Rev Microbiol 2013; 11: 836–848.
-
(2013)
Nat Rev Microbiol
, vol.11
, pp. 836-848
-
-
Graham, R.L.1
Donaldson, E.F.2
Baric, R.S.3
-
25
-
-
84875213690
-
Genetic relatedness of the novel human group C betacoronavirus to Tylonycteris bat coronavirus HKU4 and Pipistrellus bat coronavirus HKU5
-
Woo PC, Lau SK, Li KS, Tsang AK, Yuen KY. Genetic relatedness of the novel human group C betacoronavirus to Tylonycteris bat coronavirus HKU4 and Pipistrellus bat coronavirus HKU5. Emerg Microbes Infect 2012; 1: e35.
-
(2012)
Emerg Microbes Infect
, vol.1
, pp. e35
-
-
Woo, P.C.1
Lau, S.K.2
Li, K.S.3
Tsang, A.K.4
Yuen, K.Y.5
-
26
-
-
84881551712
-
The emerging novel Middle East respiratory syndrome coronavirus: The ‘knowns’ and ‘unknowns
-
Chan JF, Lau SK, Woo PC. The emerging novel Middle East respiratory syndrome coronavirus: the ‘knowns’ and ‘unknowns’. J Formos Med Assoc 2013; 112: 372–381.
-
(2013)
’. J Formos Med Assoc
, vol.112
, pp. 372-381
-
-
Chan, J.F.1
Lau, S.K.2
Woo, P.C.3
-
27
-
-
84890421987
-
State of knowledge and data gaps of Middle East respiratory syndrome coronavirus (MERS-CoV) in humans
-
Who Mers-Cov Research G, State of knowledge and data gaps of Middle East respiratory syndrome coronavirus (MERS-CoV) in humans. PLoS Curr 2013; 5: doi:10.1371/currents.outbreaks.0bf719e352e7478-f8ad85fa30127ddb8.
-
(2013)
Plos Curr
, vol.5
-
-
-
28
-
-
84875610424
-
A predicted receptor-binding and critical neutralizing domain in S protein of the novel human coronavirus HCoV-EMC
-
Jiang S, Lu L, Du L, Debnath AK. A predicted receptor-binding and critical neutralizing domain in S protein of the novel human coronavirus HCoV-EMC. JInfect2013; 66: 464–466.
-
(2013)
Jinfect
, vol.66
, pp. 464-466
-
-
Jiang, S.1
Lu, L.2
Du, L.3
Debnath, A.K.4
-
29
-
-
84874996988
-
Dipeptidyl peptidase 4 is a functional receptor for the emerging human coronavirus-EMC
-
Raj VS, Mou H, Smits SL, Dekkers DH, Muller MA, Dijkman R et al. Dipeptidyl peptidase 4 is a functional receptor for the emerging human coronavirus-EMC. Nature 2013; 495: 251–254.
-
(2013)
Nature
, vol.495
, pp. 251-254
-
-
Raj, V.S.1
Mou, H.2
Smits, S.L.3
Dekkers, D.H.4
Muller, M.A.5
Dijkman, R.6
-
30
-
-
29144451985
-
Coronavirus pathogenesis and the emerging pathogen severe acute respiratory syndrome coronavirus
-
Weiss SR, Navas-Martin S. Coronavirus pathogenesis and the emerging pathogen severe acute respiratory syndrome coronavirus. Microbiol Mol Biol Rev 2005; 69: 635–664.
-
(2005)
Microbiol Mol Biol Rev
, vol.69
, pp. 635-664
-
-
Weiss, S.R.1
Navas-Martin, S.2
-
31
-
-
60749134643
-
The spike protein of SARS-CoV—a target for vaccine and therapeutic development
-
Du L, He Y, Zhou Y, Liu S, Zheng BJ, Jiang S. The spike protein of SARS-CoV—a target for vaccine and therapeutic development. Nat Rev Microbiol 2009; 7: 226–236.
-
(2009)
Nat Rev Microbiol
, vol.7
, pp. 226-236
-
-
Du, L.1
He, Y.2
Zhou, Y.3
Liu, S.4
Zheng, B.J.5
Jiang, S.6
-
32
-
-
84881190964
-
Structure of MERS-CoV spike receptor-binding domain complexed with human receptor DPP4
-
Wang N, Shi X, Jiang L, Zhang S, Wang D, Tong P et al. Structure of MERS-CoV spike receptor-binding domain complexed with human receptor DPP4. Cell Res 2013; 23: 986–993.
-
(2013)
Cell Res
, vol.23
, pp. 986-993
-
-
Wang, N.1
Shi, X.2
Jiang, L.3
Zhang, S.4
Wang, D.5
Tong, P.6
-
33
-
-
24644441711
-
Protease-mediated enhancement of severe acute respiratory syndrome coronavirus infection
-
Matsuyama S, Ujike M, Morikawa S, Tashiro M, Taguchi F. Protease-mediated enhancement of severe acute respiratory syndrome coronavirus infection. Proc Natl Acad Sci USA 2005; 102: 12543–12547.
-
(2005)
Proc Natl Acad Sci USA
, vol.102
, pp. 12543-12547
-
-
Matsuyama, S.1
Ujike, M.2
Morikawa, S.3
Tashiro, M.4
Taguchi, F.5
-
34
-
-
33845750075
-
A contemporary view of coronavirus transcription
-
Sawicki SG, Sawicki DL, Siddell SG. A contemporary view of coronavirus transcription. J Virol 2007; 81: 20–29.
-
(2007)
J Virol
, vol.81
, pp. 20-29
-
-
Sawicki, S.G.1
Sawicki, D.L.2
Siddell, S.G.3
-
35
-
-
26944439528
-
Molecular interactions in the assembly of coronaviruses
-
de Haan CA, Rottier PJ. Molecular interactions in the assembly of coronaviruses. Adv Virus Res 2005; 64: 165–230.
-
(2005)
Adv Virus Res
, vol.64
, pp. 165-230
-
-
de Haan, C.A.1
Rottier, P.J.2
-
36
-
-
0033679958
-
Essential role for the dsRNA-dependent protein kinase PKR in innate immunity to viral infection
-
Balachandran S, Roberts PC, Brown LE, Truong H, Pattnaik AK, Archer DR et al. Essential role for the dsRNA-dependent protein kinase PKR in innate immunity to viral infection. Immunity 2000; 13: 129–141.
-
(2000)
Immunity
, vol.13
, pp. 129-141
-
-
Balachandran, S.1
Roberts, P.C.2
Brown, L.E.3
Truong, H.4
Pattnaik, A.K.5
Archer, D.R.6
-
37
-
-
80052143412
-
RIG-I-like receptors: Cytoplasmic sensors for non-self RNA
-
Kato H, Takahasi K, Fujita T. RIG-I-like receptors: cytoplasmic sensors for non-self RNA. Immunol Rev 2011; 243: 91–98.
-
(2011)
Immunol Rev
, vol.243
, pp. 91-98
-
-
Kato, H.1
Takahasi, K.2
Fujita, T.3
-
38
-
-
84875932685
-
Negative regulatory approaches to the attenuation of Toll-like receptor signaling
-
Anwar MA, Basith S, Choi S. Negative regulatory approaches to the attenuation of Toll-like receptor signaling. Exp Mol Med 2013; 45: e11.
-
(2013)
Exp Mol Med
, vol.45
, pp. e11
-
-
Anwar, M.A.1
Basith, S.2
Choi, S.3
-
39
-
-
34548844720
-
Toll-like receptor signal transduction
-
Krishnan J, Selvarajoo K, Tsuchiya M, Lee G, Choi S. Toll-like receptor signal transduction. Exp Mol Med 2007; 39: 421–438.
-
(2007)
Exp Mol Med
, vol.39
, pp. 421-438
-
-
Krishnan, J.1
Selvarajoo, K.2
Tsuchiya, M.3
Lee, G.4
Choi, S.5
-
40
-
-
0035909372
-
Recognition of double-stranded RNA and activation of NF-kappaB by Toll-like receptor 3
-
Alexopoulou L, Holt AC, Medzhitov R, Flavell RA. Recognition of double-stranded RNA and activation of NF-kappaB by Toll-like receptor 3. Nature 2001; 413: 732–738.
-
(2001)
Nature
, vol.413
, pp. 732-738
-
-
Alexopoulou, L.1
Holt, A.C.2
Medzhitov, R.3
Flavell, R.A.4
-
41
-
-
84886298565
-
Middle East respiratory syndrome coronavirus accessory protein 4a is a type I interferon antagonist
-
Niemeyer D, Zillinger T, Muth D, Zielecki F, Horvath G, Suliman T et al. Middle East respiratory syndrome coronavirus accessory protein 4a is a type I interferon antagonist. JVirol2013; 87: 12489–12495.
-
(2013)
Jvirol
, vol.87
, pp. 12489-12495
-
-
Niemeyer, D.1
Zillinger, T.2
Muth, D.3
Zielecki, F.4
Horvath, G.5
Suliman, T.6
-
42
-
-
84895534920
-
Middle east respiratory syndrome coronavirus 4a protein is a double-stranded RNA-binding protein that suppresses PACT-induced activation of RIG-I and MDA5 in the innate antiviral response
-
Siu KL, Yeung ML, Kok KH, Yuen KS, Kew C, Lui PY et al. Middle east respiratory syndrome coronavirus 4a protein is a double-stranded RNA-binding protein that suppresses PACT-induced activation of RIG-I and MDA5 in the innate antiviral response. J Virol 2014; 88: 4866–4876.
-
(2014)
J Virol
, vol.88
, pp. 4866-4876
-
-
Siu, K.L.1
Yeung, M.L.2
Kok, K.H.3
Yuen, K.S.4
Kew, C.5
Lui, P.Y.6
-
43
-
-
84893254396
-
Structure-based discovery of Middle East respiratory syndrome coronavirus fusion inhibitor
-
Lu L, Liu Q, Zhu Y, Chan KH, Qin L, Li Y et al. Structure-based discovery of Middle East respiratory syndrome coronavirus fusion inhibitor. Nat Commun 2014; 5: 3067.
-
(2014)
Nat Commun
, vol.5
, pp. 3067
-
-
Lu, L.1
Liu, Q.2
Zhu, Y.3
Chan, K.H.4
Qin, L.5
Li, Y.6
-
44
-
-
84937107017
-
Pre-and postexposure efficacy of fully human antibodies against Spike protein in a novel humanized mouse model of MERS-CoV infection
-
Pascal KE, Coleman CM, Mujica AO, Kamat V, Badithe A, Fairhurst J et al. Pre-and postexposure efficacy of fully human antibodies against Spike protein in a novel humanized mouse model of MERS-CoV infection. Proc Natl Acad Sci USA 2015; 112: 8738–8743.
-
(2015)
Proc Natl Acad Sci USA
, vol.112
, pp. 8738-8743
-
-
Pascal, K.E.1
Coleman, C.M.2
Mujica, A.O.3
Kamat, V.4
Badithe, A.5
Fairhurst, J.6
-
45
-
-
84924777934
-
Generation of a transgenic mouse model of Middle East respiratory syndrome coronavirus infection and disease
-
Agrawal AS, Garron T, Tao X, Peng BH, Wakamiya M, Chan TS et al. Generation of a transgenic mouse model of Middle East respiratory syndrome coronavirus infection and disease. J Virol 2015; 89: 3659–3670.
-
(2015)
J Virol
, vol.89
, pp. 3659-3670
-
-
Agrawal, A.S.1
Garron, T.2
Tao, X.3
Peng, B.H.4
Wakamiya, M.5
Chan, T.S.6
-
46
-
-
84938151524
-
Protective efficacy of recombinant Modified Vaccinia virus Ankara (MVA) delivering Middle East respiratory syndrome coronavirus spike glycoprotein
-
Volz A, Kupke A, Song F, Jany S, Fux R, Shams-Eldin H et al. Protective efficacy of recombinant Modified Vaccinia virus Ankara (MVA) delivering Middle East respiratory syndrome coronavirus spike glycoprotein. JVirol 2015; 89: 8651–8656.
-
(2015)
Jvirol
, vol.89
, pp. 8651-8656
-
-
Volz, A.1
Kupke, A.2
Song, F.3
Jany, S.4
Fux, R.5
Shams-Eldin, H.6
-
47
-
-
84883448281
-
Spiking the MERS-coronavirus receptor
-
Bosch BJ, Raj VS, Haagmans BL. Spiking the MERS-coronavirus receptor. Cell Res 2013; 23: 1069–1070.
-
(2013)
Cell Res
, vol.23
, pp. 1069-1070
-
-
Bosch, B.J.1
Raj, V.S.2
Haagmans, B.L.3
-
48
-
-
84892463403
-
Adenosine deaminase acts as a natural antagonist for dipeptidyl peptidase 4-mediated entry of the Middle East respiratory syndrome coronavirus
-
Raj VS, Smits SL, Provacia LB, van den Brand JM, Wiersma L, Ouwendijk WJ et al. Adenosine deaminase acts as a natural antagonist for dipeptidyl peptidase 4-mediated entry of the Middle East respiratory syndrome coronavirus. J Virol 2014; 88: 1834–1838.
-
(2014)
J Virol
, vol.88
, pp. 1834-1838
-
-
Raj, V.S.1
Smits, S.L.2
Provacia, L.B.3
van den Brand, J.M.4
Wiersma, L.5
Ouwendijk, W.J.6
-
49
-
-
84888037046
-
Inhibition of Middle East respiratory syndrome coronavirus infection by anti-CD26 monoclonal antibody
-
Ohnuma K, Haagmans BL, Hatano R, Raj VS, Mou H, Iwata S et al. Inhibition of Middle East respiratory syndrome coronavirus infection by anti-CD26 monoclonal antibody. J Virol 2013; 87: 13892–13899.
-
(2013)
J Virol
, vol.87
, pp. 13892-13899
-
-
Ohnuma, K.1
Haagmans, B.L.2
Hatano, R.3
Raj, V.S.4
Mou, H.5
Iwata, S.6
-
50
-
-
84898922309
-
What are our pharmacotherapeutic options for MERS-CoV?
-
Al-Tawfiq JA, Memish ZA. What are our pharmacotherapeutic options for MERS-CoV? Expert Rev Clin Pharmacol 2014; 7: 235–238.
-
(2014)
Expert Rev Clin Pharmacol
, vol.7
, pp. 235-238
-
-
Al-Tawfiq, J.A.1
Memish, Z.A.2
-
51
-
-
84897480727
-
Rapid generation of a mouse model for Middle East respiratory syndrome
-
Zhao J, Li K, Wohlford-Lenane C, Agnihothram SS, Fett C, Zhao J et al. Rapid generation of a mouse model for Middle East respiratory syndrome. Proc Natl Acad Sci USA 2014; 111: 4970–4975.
-
(2014)
Proc Natl Acad Sci USA
, vol.111
, pp. 4970-4975
-
-
Zhao, J.1
Li, K.2
Wohlford-Lenane, C.3
Agnihothram, S.S.4
Fett, C.5
Zhao, J.6
-
52
-
-
84890863276
-
MERS-CoV papain-like protease has deISGylating and deubiquitinating activities
-
Mielech AM, Kilianski A, Baez-Santos YM, Mesecar AD, Baker SC. MERS-CoV papain-like protease has deISGylating and deubiquitinating activities. Virology 2014; 450-451: 64–70.
-
(2014)
Virology
, vol.450-451
, pp. 64-70
-
-
Mielech, A.M.1
Kilianski, A.2
Baez-Santos, Y.M.3
Mesecar, A.D.4
Baker, S.C.5
-
53
-
-
84902359082
-
Structural and functional characterization of MERS coronavirus papain-like protease
-
Lin MH, Chuang SJ, Chen CC, Cheng SC, Cheng KW, Lin CH et al. Structural and functional characterization of MERS coronavirus papain-like protease. JBiomedSci2014; 21: 54.
-
(2014)
Jbiomedsci
, vol.21
, pp. 54
-
-
Lin, M.H.1
Chuang, S.J.2
Chen, C.C.3
Cheng, S.C.4
Cheng, K.W.5
Lin, C.H.6
-
54
-
-
84929248157
-
Structures of the Middle East respiratory syndrome coronavirus 3C-like protease reveal insights into substrate specificity
-
Needle D, Lountos GT, Waugh DS. Structures of the Middle East respiratory syndrome coronavirus 3C-like protease reveal insights into substrate specificity. Acta Crystallogr D 2015; 71: 1102–1111.
-
(2015)
Acta Crystallogr D
, vol.71
, pp. 1102-1111
-
-
Needle, D.1
Lountos, G.T.2
Waugh, D.S.3
-
55
-
-
84886921982
-
Assessing activity and inhibition of Middle East respiratory syndrome coronavirus papain-like and 3C-like proteases using luciferase-based biosensors
-
Kilianski A, Mielech AM, Deng X, Baker SC. Assessing activity and inhibition of Middle East respiratory syndrome coronavirus papain-like and 3C-like proteases using luciferase-based biosensors. J Virol 2013; 87: 11955–11962.
-
(2013)
J Virol
, vol.87
, pp. 11955-11962
-
-
Kilianski, A.1
Mielech, A.M.2
Deng, X.3
Baker, S.C.4
-
56
-
-
84890049888
-
The structural and accessory proteins M, ORF 4a, ORF 4b, and ORF 5 of Middle East respiratory syndrome coronavirus (MERS-CoV) are potent interferon antagonists
-
Yang Y, Zhang L, Geng H, Deng Y, Huang B, Guo Y et al. The structural and accessory proteins M, ORF 4a, ORF 4b, and ORF 5 of Middle East respiratory syndrome coronavirus (MERS-CoV) are potent interferon antagonists. Protein Cell 2013; 4: 951–961.
-
(2013)
Protein Cell
, vol.4
, pp. 951-961
-
-
Yang, Y.1
Zhang, L.2
Geng, H.3
Deng, Y.4
Huang, B.5
Guo, Y.6
-
57
-
-
0036343241
-
The group-specific murine coronavirus genes are not essential, but their deletion, by reverse genetics, is attenuating in the natural host
-
de Haan CA, Masters PS, Shen X, Weiss S, Rottier PJ. The group-specific murine coronavirus genes are not essential, but their deletion, by reverse genetics, is attenuating in the natural host. Virology 2002; 296: 177–189.
-
(2002)
Virology
, vol.296
, pp. 177-189
-
-
de Haan, C.A.1
Masters, P.S.2
Shen, X.3
Weiss, S.4
Rottier, P.J.5
-
58
-
-
1842432528
-
Live, attenuated coronavirus vaccines through the directed deletion of group-specific genes provide protection against feline infectious peritonitis
-
Haijema BJ, Volders H, Rottier PJ. Live, attenuated coronavirus vaccines through the directed deletion of group-specific genes provide protection against feline infectious peritonitis. J Virol 2004; 78: 3863–3871.
-
(2004)
J Virol
, vol.78
, pp. 3863-3871
-
-
Haijema, B.J.1
Volders, H.2
Rottier, P.J.3
-
59
-
-
84904545615
-
Accessory proteins of SARS-CoV and other coronaviruses
-
Liu DX, Fung TS, Chong KK, Shukla A, Hilgenfeld R. Accessory proteins of SARS-CoV and other coronaviruses. Antiviral Res 2014; 109: 97–109.
-
(2014)
Antiviral Res
, vol.109
, pp. 97-109
-
-
Liu, D.X.1
Fung, T.S.2
Chong, K.K.3
Shukla, A.4
Hilgenfeld, R.5
-
60
-
-
0034948808
-
The virus battles: IFN induction of the antiviral state and mechanisms of viral evasion
-
Levy DE, Garcia-Sastre A. The virus battles: IFN induction of the antiviral state and mechanisms of viral evasion. Cytokine Growth Factor Rev 2001; 12: 143–156.
-
(2001)
Cytokine Growth Factor Rev
, vol.12
, pp. 143-156
-
-
Levy, D.E.1
Garcia-Sastre, A.2
-
61
-
-
84897055458
-
The ORF4b-encoded accessory proteins of Middle East respiratory syndrome coronavirus and two related bat coronaviruses localize to the nucleus and inhibit innate immune signalling
-
Matthews KL, Coleman CM, van der Meer Y, Snijder EJ, Frieman MB. The ORF4b-encoded accessory proteins of Middle East respiratory syndrome coronavirus and two related bat coronaviruses localize to the nucleus and inhibit innate immune signalling. J Gen Virol 2014; 95: 874–882.
-
(2014)
J Gen Virol
, vol.95
, pp. 874-882
-
-
Matthews, K.L.1
Coleman, C.M.2
van der Meer, Y.3
Snijder, E.J.4
Frieman, M.B.5
-
62
-
-
33750067700
-
Interferon: The pathways of discovery I. Molecular and cellular aspects
-
Billiau A. Interferon: the pathways of discovery I. Molecular and cellular aspects. Cytokine Growth Factor Rev 2006; 17: 381–409.
-
(2006)
Cytokine Growth Factor Rev
, vol.17
, pp. 381-409
-
-
Billiau, A.1
-
63
-
-
34548418935
-
Toll-like receptors, RIG-I-like RNA helicases and the antiviral innate immune response
-
Thompson AJ, Locarnini SA. Toll-like receptors, RIG-I-like RNA helicases and the antiviral innate immune response. Immunol Cell Biol 2007; 85: 435–445.
-
(2007)
Immunol Cell Biol
, vol.85
, pp. 435-445
-
-
Thompson, A.J.1
Locarnini, S.A.2
-
64
-
-
34347217047
-
Triggering antiviral response by RIG-I-related RNA helicases
-
Fujita T, Onoguchi K, Onomoto K, Hirai R, Yoneyama M. Triggering antiviral response by RIG-I-related RNA helicases. Biochimie 2007; 89: 754–760.
-
(2007)
Biochimie
, vol.89
, pp. 754-760
-
-
Fujita, T.1
Onoguchi, K.2
Onomoto, K.3
Hirai, R.4
Yoneyama, M.5
-
65
-
-
80054703126
-
Structural basis for the activation of innate immune pattern-recognition receptor RIG-I by viral RNA
-
Kowalinski E, Lunardi T, McCarthy AA, Louber J, Brunel J, Grigorov B et al. Structural basis for the activation of innate immune pattern-recognition receptor RIG-I by viral RNA. Cell 2011; 147: 423–435.
-
(2011)
Cell
, vol.147
, pp. 423-435
-
-
Kowalinski, E.1
Lunardi, T.2
McCarthy, A.A.3
Louber, J.4
Brunel, J.5
Grigorov, B.6
-
66
-
-
84887019388
-
Broad-spectrum antivirals for the emerging Middle East respiratory syndrome coronavirus
-
Chan JF, Chan KH, Kao RY, To KK, Zheng BJ, Li CP et al. Broad-spectrum antivirals for the emerging Middle East respiratory syndrome coronavirus. JInfect2013; 67: 606–616.
-
(2013)
Jinfect
, vol.67
, pp. 606-616
-
-
Chan, J.F.1
Chan, K.H.2
Kao, R.Y.3
To, K.K.4
Zheng, B.J.5
Li, C.P.6
-
67
-
-
84880177352
-
MERS-coronavirus replication induces severe in vitro cytopathology and is strongly inhibited by cyclosporin A or interferon-alpha treatment
-
de Wilde AH, Raj VS, Oudshoorn D, Bestebroer TM, van Nieuwkoop S, Limpens RW et al. MERS-coronavirus replication induces severe in vitro cytopathology and is strongly inhibited by cyclosporin A or interferon-alpha treatment. J Gen Virol 2013; 94: 1749–1760.
-
(2013)
J Gen Virol
, vol.94
, pp. 1749-1760
-
-
de Wilde, A.H.1
Raj, V.S.2
Oudshoorn, D.3
Bestebroer, T.M.4
van Nieuwkoop, S.5
Limpens, R.W.6
-
68
-
-
84894028391
-
Interferon-beta and mycophenolic acid are potent inhibitors of Middle East respiratory syndrome coronavirus in cell-based assays
-
Hart BJ, Dyall J, Postnikova E, Zhou H, Kindrachuk J, Johnson RF et al. Interferon-beta and mycophenolic acid are potent inhibitors of Middle East respiratory syndrome coronavirus in cell-based assays. J Gen Virol 2014; 95: 571–577.
-
(2014)
J Gen Virol
, vol.95
, pp. 571-577
-
-
Hart, B.J.1
Dyall, J.2
Postnikova, E.3
Zhou, H.4
Kindrachuk, J.5
Johnson, R.F.6
-
69
-
-
84902176510
-
Repurposing of clinically developed drugs for treatment of Middle East respiratory syndrome coronavirus infection
-
Dyall J, Coleman CM, Hart BJ, Venkataraman T, Holbrook MR, Kindrachuk J et al. Repurposing of clinically developed drugs for treatment of Middle East respiratory syndrome coronavirus infection. Antimicrob Agents Chemother 2014; 58: 4885–4893.
-
(2014)
Antimicrob Agents Chemother
, vol.58
, pp. 4885-4893
-
-
Dyall, J.1
Coleman, C.M.2
Hart, B.J.3
Venkataraman, T.4
Holbrook, M.R.5
Kindrachuk, J.6
-
70
-
-
84903978961
-
Evaluation of SSYA10-001 as a replication inhibitor of severe acute respiratory syndrome, mouse hepatitis, and Middle East respiratory syndrome coronaviruses
-
Adedeji AO, Singh K, Kassim A, Coleman CM, Elliott R, Weiss SR et al. Evaluation of SSYA10-001 as a replication inhibitor of severe acute respiratory syndrome, mouse hepatitis, and Middle East respiratory syndrome coronaviruses. Antimicrob Agents Chemother 2014; 58: 4894–4898.
-
(2014)
Antimicrob Agents Chemother
, vol.58
, pp. 4894-4898
-
-
Adedeji, A.O.1
Singh, K.2
Kassim, A.3
Coleman, C.M.4
Elliott, R.5
Weiss, S.R.6
-
71
-
-
84905386648
-
Screening of an FDA-approved compound library identifies four small-molecule inhibitors of Middle East respiratory syndrome coronavirus replication in cell culture
-
de Wilde AH, Jochmans D, Posthuma CC, Zevenhoven-Dobbe JC, van Nieuwkoop S, Bestebroer TM et al. Screening of an FDA-approved compound library identifies four small-molecule inhibitors of Middle East respiratory syndrome coronavirus replication in cell culture. Antimicrob Agents Chemother 2014; 58: 4875–4884.
-
(2014)
Antimicrob Agents Chemother
, vol.58
, pp. 4875-4884
-
-
de Wilde, A.H.1
Jochmans, D.2
Posthuma, C.C.3
Zevenhoven-Dobbe, J.C.4
van Nieuwkoop, S.5
Bestebroer, T.M.6
-
72
-
-
84901649016
-
Targeting membrane-bound viral RNA synthesis reveals potent inhibition of diverse coronaviruses including the middle East respiratory syndrome virus
-
Lundin A, Dijkman R, Bergstrom T, Kann N, Adamiak B, Hannoun C et al. Targeting membrane-bound viral RNA synthesis reveals potent inhibition of diverse coronaviruses including the middle East respiratory syndrome virus. PLoS Pathog 2014; 10: e1004166.
-
(2014)
Plos Pathog
, vol.10
-
-
Lundin, A.1
Dijkman, R.2
Bergstrom, T.3
Kann, N.4
Adamiak, B.5
Hannoun, C.6
-
73
-
-
84928559621
-
MERS coronavirus envelope protein has a single transmembrane domain that forms pentameric ion channels
-
Surya W, Li Y, Verdia-Baguena C, Aguilella VM, Torres J. MERS coronavirus envelope protein has a single transmembrane domain that forms pentameric ion channels. Virus Res 2015; 201: 61–66.
-
(2015)
Virus Res
, vol.201
, pp. 61-66
-
-
Surya, W.1
Li, Y.2
Verdia-Baguena, C.3
Aguilella, V.M.4
Torres, J.5
-
74
-
-
84930040783
-
Middle East respiratory syndrome: An emerging coronavirus infection tracked by the crowd
-
Mackay IM, Arden KE. Middle East respiratory syndrome: an emerging coronavirus infection tracked by the crowd. Virus Res 2015; 202: 60–88.
-
(2015)
Virus Res
, vol.202
, pp. 60-88
-
-
Mackay, I.M.1
Arden, K.E.2
-
75
-
-
84890649426
-
In-vitro renal epithelial cell infection reveals a viral kidney tropism as a potential mechanism for acute renal failure during Middle East respiratory syndrome (MERS) Coronavirus infection
-
Eckerle I, Muller MA, Kallies S, Gotthardt DN, Drosten C. In-vitro renal epithelial cell infection reveals a viral kidney tropism as a potential mechanism for acute renal failure during Middle East respiratory syndrome (MERS) Coronavirus infection. Virol J 2013; 10: 359.
-
(2013)
Virol J
, vol.10
-
-
Eckerle, I.1
Muller, M.A.2
Kallies, S.3
Gotthardt, D.N.4
Drosten, C.5
-
76
-
-
84872146295
-
Human coronavirus EMC does not require the SARS-coronavirus receptor and maintains broad replicative capability in mammalian cell lines
-
Muller MA, Raj VS, Muth D, Meyer B, Kallies S, Smits SL et al. Human coronavirus EMC does not require the SARS-coronavirus receptor and maintains broad replicative capability in mammalian cell lines. MBio 2012; 3: e00515–00512.
-
(2012)
Mbio
, vol.3
, pp. e00515
-
-
Muller, M.A.1
Raj, V.S.2
Muth, D.3
Meyer, B.4
Kallies, S.5
Smits, S.L.6
-
77
-
-
84877262971
-
Differential cell line susceptibility to the emerging novel human betacoronavirus 2c EMC/2012: Implications for disease pathogenesis and clinical manifestation
-
Chan JF, Chan KH, Choi GK, To KK, Tse H, Cai JP et al. Differential cell line susceptibility to the emerging novel human betacoronavirus 2c EMC/2012: implications for disease pathogenesis and clinical manifestation. J Infect Dis 2013; 207: 1743–1752.
-
(2013)
J Infect Dis
, vol.207
, pp. 1743-1752
-
-
Chan, J.F.1
Chan, K.H.2
Choi, G.K.3
To, K.K.4
Tse, H.5
Cai, J.P.6
-
78
-
-
84892612772
-
Replicative capacity of MERS coronavirus in livestock cell lines
-
Eckerle I, Corman VM, Muller MA, Lenk M, Ulrich RG, Drosten C. Replicative capacity of MERS coronavirus in livestock cell lines. Emerg Infect Dis 2014; 20: 276–279.
-
(2014)
Emerg Infect Dis
, vol.20
, pp. 276-279
-
-
Eckerle, I.1
Corman, V.M.2
Muller, M.A.3
Lenk, M.4
Ulrich, R.G.5
Drosten, C.6
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