Middle east respiratory syndrome coronavirus NS4b protein inhibits host RNase L activation

mBio

Volumn 7, Issue 2, 2016, Pages

  Thornbrough, Joshua M ^a,e   Jha, Babal K ^b   Yount, Boyd ^c   Goldstein, Stephen A ^a   Li, Yize ^a   Elliott, Ruth ^a   Sims, Amy C ^c   Baric, Ralph S ^c,d   Silverman, Robert H ^b   Weissa, Susan R ^a  

^a UNIVERSITY OF PENNSYLVANIA   (United States)

^b LERNER RESEARCH INSTITUTE   (United States)

^c IL   (United States)

^d UNIVERSITY OF NORTH CAROLINA SCHOOL OF MEDICINE   (United States)

^e ADELPHI REAL WORLD   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

2',5' OLIGOADENYLATE SYNTHETASE; INTERFERON; NONSTRUCTURAL PROTEIN 2; NONSTRUCTURAL PROTEIN 3; NONSTRUCTURAL PROTEIN 4B; NONSTRUCTURAL PROTEIN 5; PHOSPHODIESTERASE; RIBONUCLEASE L; 2',5'-OLIGOADENYLATE; 2-5A-DEPENDENT RIBONUCLEASE; ADENINE NUCLEOTIDE; NUCLEAR LOCALIZATION SIGNAL; OLIGORIBONUCLEOTIDE; RIBONUCLEASE; VIRAL PROTEIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIVIRAL ACTIVITY; ARTICLE; BETACORONAVIRUS; C57BL 6 MOUSE; CATALYTIC EFFICIENCY; CELL LINEAGE; CONTROLLED STUDY; CORONAVIRIDAE INFECTION; CYTOPLASM; ENZYME ACTIVATION; ENZYME KINETICS; ENZYME MECHANISM; GENE EXPRESSION; HOST PATHOGEN INTERACTION; HUMAN; IN VIVO STUDY; INNATE IMMUNITY; LUNG ALVEOLUS CELL; MICHAELIS CONSTANT; MIDDLE EAST RESPIRATORY SYNDROME CORONAVIRUS; MOUSE; NONHUMAN; NUCLEAR LOCALIZATION SIGNAL; PRIORITY JOURNAL; PROTEIN MOTIF; RNA DEGRADATION; SEQUENCE ALIGNMENT; SEQUENCE HOMOLOGY; VIRUS GENE; VIRUS PATHOGENESIS; VIRUS REPLICATION; ANIMAL; ANTAGONISTS AND INHIBITORS; GENETICS; HAMSTER; IMMUNE EVASION; METABOLISM; PHYSIOLOGY;

ADENINE NUCLEOTIDES; ANIMALS; CRICETINAE; ENDORIBONUCLEASES; HOST-PATHOGEN INTERACTIONS; HUMANS; IMMUNE EVASION; MICE; MIDDLE EAST RESPIRATORY SYNDROME CORONAVIRUS; NUCLEAR LOCALIZATION SIGNALS; OLIGORIBONUCLEOTIDES; VIRAL NONSTRUCTURAL PROTEINS;

EID: 84965112401     PISSN: 21612129     EISSN: 21507511     Source Type: Journal    
DOI: 10.1128/mBio.00258-16     Document Type: Article

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