Unsupervised analysis of transcriptomics in bacterial sepsis across multiple datasets reveals three robust clusters

Critical Care Medicine

Volumn 46, Issue 6, 2018, Pages 915-925

  Sweeney, Timothy E ^a   Azad, Tej D ^a   Donato, Michele ^a   Haynes, Winston A ^a   Perumal, Thanneer M ^b   Henao, Ricardo ^c,d   Bermejo Martin, Jesús F ^e   Almansa, Raquel ^e   Tamayo, Eduardo ^e   Howrylak, Judith A ^f   Choi, Augustine ^g   Parnell, Grant P ^h   Tang, Benjamin ^h,i,j,k   Nichols, Marshall ^c   Woods, Christopher W ^c,l   Ginsburg, Geoffrey S ^c   Kingsmore, Stephen F ^m   Omberg, Larsson ^b   Mangravite, Lara M ^b   Wong, Hector R ^n,o   Tsalik, Ephraim L ^c,l   Langley, Raymond J ^p   Khatri, Purvesh ^a   more..

^a STANFORD UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b SAGE BIONETWORKS   (United States)

^c DUKE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^d Duke University   (United States)

^e HOSPITAL CLÍNICO UNIVERSITARIO DE VALLADOLID   (Spain)

^f PENN STATE MILTON S HERSHEY MEDICAL CENTER   (United States)

^g WEILL CORNELL MEDICAL CENTER   (United States)

^h WESTMEAD HOSPITAL   (Australia)

ⁱ NEPEAN HOSPITAL   (Australia)

^j UNIVERSITY OF SYDNEY   (Australia)

^k University of Sydney   (Australia)

^l DURHAM VA HEALTH CARE SYSTEM   (United States)

^m RADY CHILDREN S INSTITUTE FOR GENOMIC MEDICINE   (United States)

ⁿ CINCINNATI CHILDREN S HOSPITAL RESEARCH FOUNDATION   (United States)

^o UNIVERSITY OF CINCINNATI COLLEGE OF MEDICINE   (United States)

^p UNIVERSITY OF SOUTH ALABAMA COLLEGE OF MEDICINE   (United States)

more..

Author keywords

Cluster analysis; Gene expression; Machine learning; Precision medicine; Sepsis

Indexed keywords

INTERLEUKIN 1 RECEPTOR;

ADULT; ARTICLE; BLOOD CLOTTING DISORDER; DISEASE SEVERITY; FEMALE; GENE EXPRESSION; HUMAN; LEUKOCYTE COUNT; LYMPHOCYTE; MACHINE LEARNING; MAJOR CLINICAL STUDY; MALE; MIDDLE AGED; MONOCYTE; MORTALITY RATE; PRIORITY JOURNAL; RETROSPECTIVE STUDY; SEPSIS; TRANSCRIPTOMICS; ADAPTIVE IMMUNITY; ADOLESCENT; AGED; CLUSTER ANALYSIS; GENE EXPRESSION PROFILING; GENETICS; INFLAMMATION; INFORMATION PROCESSING; INNATE IMMUNITY; MICROBIOLOGY; YOUNG ADULT;

ADAPTIVE IMMUNITY; ADOLESCENT; ADULT; AGED; BLOOD COAGULATION DISORDERS; CLUSTER ANALYSIS; DATASETS AS TOPIC; FEMALE; GENE EXPRESSION PROFILING; HUMANS; IMMUNITY, INNATE; INFLAMMATION; MALE; MIDDLE AGED; RETROSPECTIVE STUDIES; SEPSIS; YOUNG ADULT;

EID: 85051071963     PISSN: 00903493     EISSN: 15300293     Source Type: Journal    
DOI: 10.1097/CCM.0000000000003084     Document Type: Article

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