Developing a clinically feasible personalized medicine approach to pediatric septic shock

American Journal of Respiratory and Critical Care Medicine

Volumn 191, Issue 3, 2015, Pages 309-315

  Wong, Hector R ^a,b   Cvijanovich, Natalie Z ^c   Anas, Nick ^d   Allen, Geoffrey L ^e   Thomas, Neal J ^f   Bigham, Michael T ^g   Weiss, Scott L ^h   Fitzgerald, Julie ^h   Checchia, Paul A ⁱ   Meyer, Keith ^j   Shanley, Thomas P ^k   Quasney, Michael ^k   Hall, Mark ^l   Gedeit, Rainer ^m   Freishtat, Robert J ⁿ   Nowak, Jeffrey ^o   Shekhar, Raj S ^p   Gertz, Shira ^q   Dawson, Emily ^r   Howard, Kelli ^a   Harmon, Kelli ^a   Beckman, Eileen ^a   Frank, Erin ^a   Lindsell, Christopher J ^b   more..

^a CINCINNATI CHILDREN S HOSPITAL RESEARCH FOUNDATION   (United States)

^b UNIVERSITY OF CINCINNATI COLLEGE OF MEDICINE   (United States)

^c CHILDREN S HOSPITAL OAKLAND   (United States)

^d CHILDREN S HOSPITAL OF ORANGE COUNTY   (United States)

^e CHILDREN S MERCY HOSPITAL   (United States)

^f PENN STATE CHILDREN S HOSPITAL   (United States)

^g AKRON CHILDREN'S HOSPITAL   (United States)

^h CHILDREN S HOSPITAL OF PHILADELPHIA   (United States)

ⁱ TEXAS CHILDREN S HOSPITAL   (United States)

^j MIAMI CHILDREN'S HOSPITAL   (United States)

^k UNIVERSITY OF MICHIGAN   (United States)

^l NATIONWIDE CHILDREN S HOSPITAL   (United States)

^m Children's Hospital of Wisconsin ^*  (United States)

ⁿ CHILDREN'S NATIONAL MEDICAL CENTER   (United States)

^o CHILDREN S HOSPITALS AND CLINICS OF MINNESOTA   (United States)

^p RILEY HOSPITAL FOR CHILDREN   (United States)

^q HACKENSACK UNIVERSITY MEDICAL CENTER   (United States)

^r UNIVERSITY OF CHICAGO   (United States)

more..

Author keywords

Adaptive immunity; Gene expression; Glucocorticoids; Sepsis; Subclassification

Indexed keywords

CORTICOSTEROID; GLUCOCORTICOID RECEPTOR; MESSENGER RNA; GLUCOCORTICOID;

ADAPTIVE IMMUNITY; AREA UNDER THE CURVE; ARTICLE; CHILD; COMPUTER ANALYSIS; CORTICOSTEROID THERAPY; DISEASE CLASSIFICATION; FEASIBILITY STUDY; FEMALE; GENE EXPRESSION; HUMAN; IMAGE ANALYSIS; INTENSIVE CARE; MAJOR CLINICAL STUDY; MALE; MEDICAL DECISION MAKING; MICROARRAY ANALYSIS; MORTALITY; MOSAICISM; PERSONALIZED MEDICINE; PHYSICIAN; PRIORITY JOURNAL; SEPTIC SHOCK; VALIDATION STUDY; COMPARATIVE STUDY; GENE EXPRESSION REGULATION; GENETICS; INFANT; MATHEMATICAL COMPUTING; ODDS RATIO; PEDIATRIC INTENSIVE CARE UNIT; PHENOTYPE; PRESCHOOL CHILD; PROSPECTIVE STUDY; REPRODUCIBILITY; SEVERITY OF ILLNESS INDEX; SHOCK, SEPTIC; SIGNAL TRANSDUCTION;

CHILD; CHILD, PRESCHOOL; FEASIBILITY STUDIES; FEMALE; GENE EXPRESSION REGULATION; GLUCOCORTICOIDS; HUMANS; INFANT; INTENSIVE CARE UNITS, PEDIATRIC; MALE; MATHEMATICAL COMPUTING; ODDS RATIO; PHENOTYPE; PRECISION MEDICINE; PROSPECTIVE STUDIES; REPRODUCIBILITY OF RESULTS; SEVERITY OF ILLNESS INDEX; SHOCK, SEPTIC; SIGNAL TRANSDUCTION;

EID: 84922311029     PISSN: 1073449X     EISSN: 15354970     Source Type: Journal    
DOI: 10.1164/rccm.201410-1864OC     Document Type: Article

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