Inflammasome-regulated cytokines are critical mediators of acute lung injury

American Journal of Respiratory and Critical Care Medicine

Volumn 185, Issue 11, 2012, Pages 1225-1234

  Dolinay, Tamás ^a   Kim, Young Sam ^a   Howrylak, Judie ^a,b   Hunninghake, Gary M ^a,b   An, Chang Hyeok ^a   Fredenburgh, Laura ^a   Massaro, Anthony F ^a   Rogers, Angela ^a,b   Gazourian, Lee ^a   Nakahira, Kiichi ^a   Haspel, Jeffrey A ^a   Landazury, Roberto ^a   Eppanapally, Sabitha ^a   Christie, Jason D ^c   Meyer, Nuala J ^c   Ware, Lorraine B ^d   Christiani, David C ^e,f   Ryter, Stefan W ^a   Baron, Rebecca M ^a   Choi, Augustine M K ^a  

^a BRIGHAM AND WOMEN S HOSPITAL   (United States)

^b CHANNING LABORATORY   (United States)

^c UNIVERSITY OF PENNSYLVANIA   (United States)

^d VANDERBILT UNIVERSITY   (United States)

^e MASSACHUSETTS GENERAL HOSPITAL   (United States)

^f HARVARD SCHOOL OF PUBLIC HEALTH   (United States)

Author keywords

Acute respiratory distress syndrome; Inflammasome; Interleukin 18; Mechanical ventilation

Indexed keywords

INFLAMMASOME; INTERLEUKIN 18; INTERLEUKIN 1BETA; INTERLEUKIN 1BETA CONVERTING ENZYME; MESSENGER RNA;

ACUTE LUNG INJURY; ADULT RESPIRATORY DISTRESS SYNDROME; ARTICLE; ARTIFICIAL VENTILATION; CRITICALLY ILL PATIENT; GENE DELETION; GENE EXPRESSION PROFILING; HUMAN; INTENSIVE CARE UNIT; LUNG LAVAGE; LUNG VOLUME; PRIORITY JOURNAL; REAL TIME POLYMERASE CHAIN REACTION; SEPSIS;

ACUTE LUNG INJURY; ADAPTIVE IMMUNITY; ANIMALS; BIOLOGICAL MARKERS; BRONCHOALVEOLAR LAVAGE FLUID; CASPASE 1; COHORT STUDIES; CRITICAL CARE; CYTOKINES; DISEASE MODELS, ANIMAL; FEMALE; HUMANS; IMMUNITY, INNATE; INFLAMMASOMES; INTENSIVE CARE UNITS; INTERLEUKIN-18; MALE; MICE; MICE, TRANSGENIC; MICROARRAY ANALYSIS; REAL-TIME POLYMERASE CHAIN REACTION; RESPIRATION, ARTIFICIAL; RESPIRATORY DISTRESS SYNDROME, ADULT; SEVERITY OF ILLNESS INDEX;

EID: 84861785677     PISSN: 1073449X     EISSN: 15354970     Source Type: Journal    
DOI: 10.1164/rccm.201201-0003OC     Document Type: Article

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