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Volumn 39, Issue 11, 2011, Pages 2511-2517

Validation of a gene expression-based subclassification strategy for pediatric septic shock

(21)  Wong, Hector R a   Cvijanovich, Natalie Z b   Allen, Geoffrey L c   Thomas, Neal J d   Freishtat, Robert J e   Anas, Nick f   Meyer, Keith g   Checchia, Paul A h   Lin, Richard i   Shanley, Thomas P j   Bigham, Michael T k   Wheeler, Derek S a   Doughty, Lesley A a   Tegtmeyer, Ken a   Poynter, Sue E a   Kaplan, Jennifer M a   Chima, Ranjit S a   Stalets, Erika a   Basu, Rajit K a   Varisco, Brian M a   more..


Author keywords

gene expression; microarray; pediatrics; septic shock; staging; stratification

Indexed keywords

GLUCOCORTICOID RECEPTOR;

EID: 80054882327     PISSN: 00903493     EISSN: 15300293     Source Type: Journal    
DOI: 10.1097/CCM.0b013e3182257675     Document Type: Article
Times cited : (109)

References (38)
  • 1
    • 77951855187 scopus 로고    scopus 로고
    • The host response to sepsis and developmental impact
    • Wynn J, Cornell TT, Wong HR, et al: The host response to sepsis and developmental impact. Pediatrics 2010; 125:1031-1041
    • (2010) Pediatrics , vol.125 , pp. 1031-1041
    • Wynn, J.1    Cornell, T.T.2    Wong, H.R.3
  • 2
    • 0037426726 scopus 로고    scopus 로고
    • The pathophysiology and treatment of sepsis
    • DOI 10.1056/NEJMra021333
    • Hotchkiss RS, Karl IE: The pathophysiology and treatment of sepsis. N Engl J Med 2003; 348:138-150 (Pubitemid 36056721)
    • (2003) New England Journal of Medicine , vol.348 , Issue.2 , pp. 138-150
    • Hotchkiss, R.S.1    Karl, I.E.2
  • 3
    • 43349108280 scopus 로고    scopus 로고
    • Sepsis: Rethinking the approach to clinical research
    • DOI 10.1189/jlb.0607380
    • Marshall JC: Sepsis: Rethinking the approach to clinical research. J Leukoc Biol 2008; 83: 471-482 (Pubitemid 351966853)
    • (2008) Journal of Leukocyte Biology , vol.83 , Issue.3 , pp. 471-482
    • Marshall, J.C.1
  • 5
    • 36448989706 scopus 로고    scopus 로고
    • Pediatric septic shock treatment: New clues from genomic profiling
    • DOI 10.2217/14622416.8.10.1287
    • Wong HR: Pediatric septic shock treatment: New clues from genomic profiling. Pharmacogenomics 2007; 8:1287-1290 (Pubitemid 350162844)
    • (2007) Pharmacogenomics , vol.8 , Issue.10 , pp. 1287-1290
    • Wong, H.R.1
  • 6
    • 70349239233 scopus 로고    scopus 로고
    • Identification of pediatric septic shock subclasses based on genome-wide expression profiling
    • Wong HR, Cvijanovich N, Lin R, et al: Identification of pediatric septic shock subclasses based on genome-wide expression profiling. BMC Med 2009; 7:34
    • (2009) BMC Med , vol.7 , pp. 34
    • Wong, H.R.1    Cvijanovich, N.2    Lin, R.3
  • 7
    • 77957235521 scopus 로고    scopus 로고
    • Toward a clinically feasible gene expressionbased subclassification strategy for septic shock: Proof of concept
    • Wong HR, Wheeler DS, Tegtmeyer K, et al: Toward a clinically feasible gene expressionbased subclassification strategy for septic shock: Proof of concept. Crit Care Med 2010; 38:1955-1961
    • (2010) Crit Care Med , vol.38 , pp. 1955-1961
    • Wong, H.R.1    Wheeler, D.S.2    Tegtmeyer, K.3
  • 8
    • 21644438082 scopus 로고    scopus 로고
    • International pediatric sepsis consensus conference: Definitions for sepsis and organ dysfunction in pediatrics
    • Goldstein B, Giroir B, Randolph A: International pediatric sepsis consensus conference: Definitions for sepsis and organ dysfunction in pediatrics. Pediatr Crit Care Med 2005; 6:2-8
    • (2005) Pediatr Crit Care Med , vol.6 , pp. 2-8
    • Goldstein, B.1    Giroir, B.2    Randolph, A.3
  • 9
    • 67650470273 scopus 로고    scopus 로고
    • Genomic expression profiling across the pediatric systemic inflammatory response syndrome, sepsis, and septic shock spectrum
    • Wong HR, Cvijanovich N, Allen GL, et al: Genomic expression profiling across the pediatric systemic inflammatory response syndrome, sepsis, and septic shock spectrum. Crit Care Med 2009; 37:1558-1566
    • (2009) Crit Care Med , vol.37 , pp. 1558-1566
    • Wong, H.R.1    Cvijanovich, N.2    Allen, G.L.3
  • 11
    • 0031467847 scopus 로고    scopus 로고
    • The Pediatric Risk of Mortality III-Acute Physiology Score (PRISM III- APS): A method of assessing physiologic instability for pediatric intensive care unit patients
    • DOI 10.1016/S0022-3476(97)70065-9
    • Pollack MM, Patel KM, Ruttimann UE: The Pediatric Risk of Mortality III-Acute Physiology Score (PRISM III-APS): A method of assessing physiologic instability for pediatric intensive care unit patients. J Pediatr 1997; 131:575-581 (Pubitemid 28006932)
    • (1997) Journal of Pediatrics , vol.131 , Issue.4 , pp. 575-581
    • Pollack, M.M.1    Patel, K.M.2    Ruttimann, U.E.3
  • 13
    • 47249122242 scopus 로고    scopus 로고
    • Validating the genomic signature of pediatric septic shock
    • Cvijanovich N, Shanley TP, Lin R, et al: Validating the genomic signature of pediatric septic shock. Physiol Genomics 2008; 34: 127-134
    • (2008) Physiol Genomics , vol.34 , pp. 127-134
    • Cvijanovich, N.1    Shanley, T.P.2    Lin, R.3
  • 14
    • 77952314473 scopus 로고    scopus 로고
    • Leukocyte subset-derived genome-wide expression profiles in pediatric septic shock
    • Wong HR, Freishtat RJ, Monaco M, et al: Leukocyte subset-derived genome-wide expression profiles in pediatric septic shock. Pediatr Crit Care Med 2010; 11:349-355
    • (2010) Pediatr Crit Care Med , vol.11 , pp. 349-355
    • Wong, H.R.1    Freishtat, R.J.2    Monaco, M.3
  • 15
    • 0142121516 scopus 로고    scopus 로고
    • Exploration, normalization, and summaries of high density oligonucleotide array probe level data
    • Irizarry RA, Hobbs B, Collin F, et al: Exploration, normalization, and summaries of high density oligonucleotide array probe level data. Biostatistics 2003; 4:249-264
    • (2003) Biostatistics , vol.4 , pp. 249-264
    • Irizarry, R.A.1    Hobbs, B.2    Collin, F.3
  • 16
    • 0344464733 scopus 로고    scopus 로고
    • Gene Expression Dynamics Inspector (GEDI): For integrative analysis of expression profiles
    • DOI 10.1093/bioinformatics/btg307
    • Eichler GS, Huang S, Ingber DE: Gene Expression Dynamics Inspector (GEDI): For integrative analysis of expression profiles. Bioinformatics 2003; 19:2321-2322 (Pubitemid 37483992)
    • (2003) Bioinformatics , vol.19 , Issue.17 , pp. 2321-2322
    • Eichler, G.S.1    Huang, S.2    Ingber, D.E.3
  • 17
    • 34247482586 scopus 로고    scopus 로고
    • Towards a holistic, yet gene-centered analysis of gene expression profiles: A case study of human lung cancers
    • Guo Y, Eichler GS, Feng Y, et al: Towards a holistic, yet gene-centered analysis of gene expression profiles: A case study of human lung cancers. J Biomed Biotechnol 2006; 2006:69141
    • (2006) J Biomed Biotechnol , vol.2006 , pp. 69141
    • Guo, Y.1    Eichler, G.S.2    Feng, Y.3
  • 18
    • 33845548419 scopus 로고    scopus 로고
    • Decreased platelet expression of myosin regulatory light chain polypeptide (MYL9) and other genes with platelet dysfunction and CBFA2/RUNX1 mutation: Insights from platelet expression profiling
    • DOI 10.1111/j.1538-7836.2006.02271.x
    • Sun L, Gorospe JR, Hoffman EP, et al: Decreased platelet expression of myosin regulatory light chain polypeptide (MYL9) and other genes with platelet dysfunction and CBFA2/RUNX1 mutation: Insights from platelet expression profiling. J Thromb Haemost 2007; 5:146-154 (Pubitemid 44921080)
    • (2007) Journal of Thrombosis and Haemostasis , vol.5 , Issue.1 , pp. 146-154
    • Sun, L.1    Gorospe, J.R.2    Hoffman, E.P.3    Rao, A.K.4
  • 19
    • 78650624395 scopus 로고    scopus 로고
    • Genomewide transcription profiling of human sepsis: A systematic review
    • Tang BM, Huang SJ, McLean AS: Genomewide transcription profiling of human sepsis: A systematic review. Crit Care 2010; 14:R237
    • (2010) Crit Care , vol.14
    • Tang, B.M.1    Huang, S.J.2    McLean, A.S.3
  • 20
    • 0032133776 scopus 로고    scopus 로고
    • Systemic inflammatory response syndrome (SIRS), multiple organ dysfunction syndrome (MODS), multiple organ failure (MOF): Are we winning the battle?
    • Baue AE, Durham R, Faist E: Systemic inflammatory response syndrome (SIRS), multiple organ dysfunction syndrome (MODS), multiple organ failure (MOF): Are we winning the battle? Shock 1998; 10:79-89 (Pubitemid 128463838)
    • (1998) Shock , vol.10 , Issue.2 , pp. 79-89
    • Baue, A.E.1    Durham, R.2    Faist, E.3
  • 21
    • 0029853587 scopus 로고    scopus 로고
    • Influence of multiple organ dysfunction syndrome on duration of critical illness and hospitalization
    • discussion 1324
    • Barie PS, Hydo LJ: Influence of multiple organ dysfunction syndrome on duration of critical illness and hospitalization. Arch Surg 1996; 131:1318-1323, discussion 1324
    • (1996) Arch Surg , vol.131 , pp. 1318-1323
    • Barie, P.S.1    Hydo, L.J.2
  • 22
    • 70349904513 scopus 로고    scopus 로고
    • Day 1 multiple organ dysfunction syndrome is associated with poor functional outcome and mortality in the pediatric intensive care unit
    • Typpo KV, Petersen NJ, Hallman DM, et al: Day 1 multiple organ dysfunction syndrome is associated with poor functional outcome and mortality in the pediatric intensive care unit. Pediatr Crit Care Med 2009; 10: 562-570
    • (2009) Pediatr Crit Care Med , vol.10 , pp. 562-570
    • Typpo, K.V.1    Petersen, N.J.2    Hallman, D.M.3
  • 23
    • 74049085767 scopus 로고    scopus 로고
    • Ten reasons why we should NOT use severity scores as entry criteria for clinical trials or in our treatment decisions
    • Vincent JL, Opal SM, Marshall JC: Ten reasons why we should NOT use severity scores as entry criteria for clinical trials or in our treatment decisions. Crit Care Med 2010; 38: 283-287
    • (2010) Crit Care Med , vol.38 , pp. 283-287
    • Vincent, J.L.1    Opal, S.M.2    Marshall, J.C.3
  • 24
    • 63149090537 scopus 로고    scopus 로고
    • Readmission and late mortality after pediatric severe sepsis
    • Czaja AS, Zimmerman JJ, Nathens AB: Readmission and late mortality after pediatric severe sepsis. Pediatrics 2009; 123:849-857
    • (2009) Pediatrics , vol.123 , pp. 849-857
    • Czaja, A.S.1    Zimmerman, J.J.2    Nathens, A.B.3
  • 26
    • 19444364187 scopus 로고    scopus 로고
    • Scope and epidemiology of pediatric sepsis
    • DOI 10.1097/01.PCC.0000161289.22464.C3
    • Watson RS, Carcillo JA: Scope and epidemiology of pediatric sepsis. Pediatr Crit Care Med 2005; 6(Suppl):S3-S5 (Pubitemid 40724243)
    • (2005) Pediatric Critical Care Medicine , vol.6 , Issue.3 SUPPL.
    • Watson, R.S.1    Carcillo, J.A.2
  • 28
    • 77954183132 scopus 로고    scopus 로고
    • Immunotherapy for sepsis-A new approach against an ancient foe
    • Hotchkiss RS, Opal S: Immunotherapy for sepsis-A new approach against an ancient foe. N Engl J Med 2010; 363:87-89
    • (2010) N Engl J Med , vol.363 , pp. 87-89
    • Hotchkiss, R.S.1    Opal, S.2
  • 29
    • 65249105408 scopus 로고    scopus 로고
    • Enhanced T cell recovery in HIV-1-infected adults through IL-7 treatment
    • Levy Y, Lacabaratz C, Weiss L, et al: Enhanced T cell recovery in HIV-1-infected adults through IL-7 treatment. J Clin Invest 2009; 119:997-1007
    • (2009) J Clin Invest , vol.119 , pp. 997-1007
    • Levy, Y.1    Lacabaratz, C.2    Weiss, L.3
  • 31
    • 67650590873 scopus 로고    scopus 로고
    • IL-7 administration drives T cell-cycle entry and expansion in HIV-1 infection
    • Sereti I, Dunham RM, Spritzler J, et al: IL-7 administration drives T cell-cycle entry and expansion in HIV-1 infection. Blood 2009; 113:6304-6314
    • (2009) Blood , vol.113 , pp. 6304-6314
    • Sereti, I.1    Dunham, R.M.2    Spritzler, J.3
  • 33
    • 77951648850 scopus 로고    scopus 로고
    • IL-7 promotes T cell viability, trafficking, and functionality and improves survival in sepsis
    • Unsinger J, McGlynn M, Kasten KR, et al: IL-7 promotes T cell viability, trafficking, and functionality and improves survival in sepsis. J Immunol 2010; 184:3768-3779
    • (2010) J Immunol , vol.184 , pp. 3768-3779
    • Unsinger, J.1    McGlynn, M.2    Kasten, K.R.3
  • 35
    • 0037151571 scopus 로고    scopus 로고
    • Effect of treatment with low doses of hydrocortisone and fludrocortisone on mortality in patients with septic shock
    • Annane D, Sebille V, Charpentier C, et al: Effect of treatment with low doses of hydrocortisone and fludrocortisone on mortality in patients with septic shock. JAMA 2002; 288: 862-871
    • (2002) JAMA , vol.288 , pp. 862-871
    • Annane, D.1    Sebille, V.2    Charpentier, C.3
  • 36
    • 38049110809 scopus 로고    scopus 로고
    • Hydrocortisone therapy for patients with septic shock
    • Sprung CL, Annane D, Keh D, et al: Hydrocortisone therapy for patients with septic shock. N Engl J Med 2008; 358:111-124
    • (2008) N Engl J Med , vol.358 , pp. 111-124
    • Sprung, C.L.1    Annane, D.2    Keh, D.3
  • 37
    • 67650486328 scopus 로고    scopus 로고
    • Stratification is the key: Inflammatory biomarkers accurately direct immunomodulatory therapy in experimental sepsis
    • Osuchowski MF, Connett J, Welch K, et al: Stratification is the key: Inflammatory biomarkers accurately direct immunomodulatory therapy in experimental sepsis. Crit Care Med 2009; 37:1567-1573
    • (2009) Crit Care Med , vol.37 , pp. 1567-1573
    • Osuchowski, M.F.1    Connett, J.2    Welch, K.3
  • 38
    • 48249148704 scopus 로고    scopus 로고
    • Interleukin-8 as a stratification tool for interventional trials involving pediatric septic shock
    • Wong HR, Cvijanovich N, Wheeler DS, et al: Interleukin-8 as a stratification tool for interventional trials involving pediatric septic shock. Am J Respir Crit Care Med 2008; 178:276-282
    • (2008) Am J Respir Crit Care Med , vol.178 , pp. 276-282
    • Wong, H.R.1    Cvijanovich, N.2    Wheeler, D.S.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.