Novel biomarker combination improves the diagnosis of serious bacterial infections in Malawian children

BMC Medical Genomics

Volumn 5, Issue , 2012, Pages

  Irwin, Adam D ^a   Marriage, Fiona ^c   Mankhambo, Limangeni A ^b,e   Jeffers, Graham ^a   Kolamunnage Dona, Ruwanthi ^a   Guiver, Malcolm ^d   Denis, Brigitte ^b   Molyneux, Elizabeth M ^e   Molyneux, Malcolm E ^b   Day, Philip J ^c   Carrol, Enitan D ^a,b,e  

^a UNIVERSITY OF LIVERPOOL   (United Kingdom)

^b MALAWI LIVERPOOL WELLCOME TRUST CLINICAL RESEARCH PROGRAMME   (Malawi)

^c UNIVERSITY OF MANCHESTER   (United Kingdom)

^d PUBLIC HEALTH ENGLAND   (United Kingdom)

^e UNIVERSITY OF MALAWI   (Malawi)

Author keywords

Bacterial infection; Biology; Biomarker; Diagnosis; Neutrophil associated gelatinase; Procalcitonin; Protein; Resistin; Transcriptomics

Indexed keywords

GRANULYSIN; NEUTROPHIL GELATINASE ASSOCIATED LIPOCALIN; PROCALCITONIN; RESISTIN;

ADOLESCENT; AREA UNDER THE CURVE; ARTICLE; BACTERIAL INFECTION; CASE CONTROL STUDY; CHILD; CONTROLLED STUDY; DIAGNOSTIC TEST ACCURACY STUDY; DIAGNOSTIC VALUE; DISEASE SEVERITY; ENZYME LINKED IMMUNOSORBENT ASSAY; FEMALE; GENE EXPRESSION; HUMAN; IMMUNOASSAY; INFANT; MAJOR CLINICAL STUDY; MALE; MENINGITIS; PNEUMONIA; PREDICTIVE VALUE; PRESCHOOL CHILD; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN BLOOD LEVEL; REAL TIME POLYMERASE CHAIN REACTION; SCHOOL CHILD; SENSITIVITY AND SPECIFICITY; SURVIVOR; TRANSCRIPTOMICS; VALIDITY;

ACUTE-PHASE PROTEINS; ANTIGENS, DIFFERENTIATION, T-LYMPHOCYTE; BACTERIAL INFECTIONS; BIOLOGICAL MARKERS; CALCITONIN; CASE-CONTROL STUDIES; CHILD; CHILD, PRESCHOOL; FEMALE; GENE EXPRESSION REGULATION; HUMANS; INFANT; LIPOCALINS; MALAWI; MALE; MODELS, BIOLOGICAL; PROTEIN PRECURSORS; PROTO-ONCOGENE PROTEINS; RESISTIN; ROC CURVE; SURVIVAL ANALYSIS;

BACTERIA (MICROORGANISMS);

EID: 84860500036     PISSN: None     EISSN: 17558794     Source Type: Journal    
DOI: 10.1186/1755-8794-5-13     Document Type: Article

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