-
1
-
-
85017447027
-
Chronic complications of diabetes mellitus: a mini review
-
Lotfy M, Adeghate J, Kalasz H, Singh J, Adeghate E. Chronic complications of diabetes mellitus: a mini review. Curr Diab Rev. 2017;13:3-10.
-
(2017)
Curr Diab Rev
, vol.13
, pp. 3-10
-
-
Lotfy, M.1
Adeghate, J.2
Kalasz, H.3
Singh, J.4
Adeghate, E.5
-
2
-
-
38949210220
-
Effect of a multifactorial intervention on mortality in type 2 diabetes
-
Gaede P, Lund-Andersen H, Parving H-H, Pedersen O. Effect of a multifactorial intervention on mortality in type 2 diabetes. N Engl J Med. 2008;358:580-91.
-
(2008)
N Engl J Med
, vol.358
, pp. 580-591
-
-
Gaede, P.1
Lund-Andersen, H.2
Parving, H.-H.3
Pedersen, O.4
-
3
-
-
84969376984
-
Executive summary: heart disease and stroke statistics-2016 update: a report from the american heart association
-
Mozaffarian D, Benjamin EJ, Go AS, Arnett DK, Blaha MJ, Cushman M, et al. Executive summary: heart disease and stroke statistics-2016 update: a report from the american heart association. Circulation. 2016;133:447-54.
-
(2016)
Circulation
, vol.133
, pp. 447-454
-
-
Mozaffarian, D.1
Benjamin, E.J.2
Go, A.S.3
Arnett, D.K.4
Blaha, M.J.5
Cushman, M.6
-
4
-
-
84898920521
-
Diabetic cardiomyopathy: mechanisms and new treatment strategies targeting antioxidant signaling pathways
-
Huynh K, Bernardo BC, McMullen JR, Ritchie RH. Diabetic cardiomyopathy: mechanisms and new treatment strategies targeting antioxidant signaling pathways. Pharmacol Ther. 2014;142:375-415.
-
(2014)
Pharmacol Ther
, vol.142
, pp. 375-415
-
-
Huynh, K.1
Bernardo, B.C.2
McMullen, J.R.3
Ritchie, R.H.4
-
5
-
-
84866599586
-
Diabetic cardiomyopathy: bench to bedside
-
Schilling JD, Mann DL. Diabetic cardiomyopathy: bench to bedside. Heart Fail Clin. 2012;8:619-31.
-
(2012)
Heart Fail Clin.
, vol.8
, pp. 619-631
-
-
Schilling, J.D.1
Mann, D.L.2
-
6
-
-
18144392274
-
Oxidative stress and fibrosis in incipient myocardial dysfunction in type 2 diabetic patients
-
González-Vílchez F, Ayuela J, Ares M, Pi J, Castillo L, Martín-Durán R. Oxidative stress and fibrosis in incipient myocardial dysfunction in type 2 diabetic patients. Int J Cardiol. 2005;101:53-8.
-
(2005)
Int J Cardiol
, vol.101
, pp. 53-58
-
-
González-Vílchez, F.1
Ayuela, J.2
Ares, M.3
Pi, J.4
Castillo, L.5
Martín-Durán, R.6
-
7
-
-
85018379155
-
Are targeted therapies for diabetic cardiomyopathy on the horizon?
-
Tate M, Grieve DJ, Ritchie RH. Are targeted therapies for diabetic cardiomyopathy on the horizon? Clin Sci Lond Engl. 1979;2017(131):897-915.
-
(1979)
Clin Sci Lond Engl
, vol.2017
, Issue.131
, pp. 897-915
-
-
Tate, M.1
Grieve, D.J.2
Ritchie, R.H.3
-
8
-
-
85019072998
-
Sodium-glucose co-transporters and their inhibition: clinical physiology
-
Ferrannini E. Sodium-glucose co-transporters and their inhibition: clinical physiology. Cell Metab. 2017;26:27-38.
-
(2017)
Cell Metab
, vol.26
, pp. 27-38
-
-
Ferrannini, E.1
-
9
-
-
84943234625
-
Localizations of Na(+)-d-glucose cotransporters SGLT1 and SGLT2 in human kidney and of SGLT1 in human small intestine, liver, lung, and heart
-
Vrhovac I, Balen Eror D, Klessen D, Burger C, Breljak D, Kraus O, et al. Localizations of Na(+)-d-glucose cotransporters SGLT1 and SGLT2 in human kidney and of SGLT1 in human small intestine, liver, lung, and heart. Pflugers Arch. 2015;467:1881-98.
-
(2015)
Pflugers Arch
, vol.467
, pp. 1881-1898
-
-
Vrhovac, I.1
Balen Eror, D.2
Klessen, D.3
Burger, C.4
Breljak, D.5
Kraus, O.6
-
10
-
-
85021187904
-
Role of SGLT2 inhibitors in patients with diabetes mellitus and heart failure
-
Verbrugge FH. Role of SGLT2 inhibitors in patients with diabetes mellitus and heart failure. Curr Heart Fail Rep. 2017;14:275-83.
-
(2017)
Curr Heart Fail Rep.
, vol.14
, pp. 275-283
-
-
Verbrugge, F.H.1
-
11
-
-
84996551945
-
Evaluation of the pharmacokinetics, pharmacodynamics and clinical efficacy of empagliflozin for the treatment of type 2 diabetes
-
Tomlinson B, Hu M, Zhang Y, Chan P, Liu Z-M. Evaluation of the pharmacokinetics, pharmacodynamics and clinical efficacy of empagliflozin for the treatment of type 2 diabetes. Expert Opin Drug Metab Toxicol. 2017;13:211-23.
-
(2017)
Expert Opin Drug Metab Toxicol.
, vol.13
, pp. 211-223
-
-
Tomlinson, B.1
Hu, M.2
Zhang, Y.3
Chan, P.4
Liu, Z.-M.5
-
12
-
-
84944800184
-
Empagliflozin, cardiovascular outcomes, and mortality in type 2 diabetes
-
Zinman B, Wanner C, Lachin JM, Fitchett D, Bluhmki E, Hantel S, et al. Empagliflozin, cardiovascular outcomes, and mortality in type 2 diabetes. N Engl J Med. 2015;373:2117-28.
-
(2015)
N Engl J Med
, vol.373
, pp. 2117-2128
-
-
Zinman, B.1
Wanner, C.2
Lachin, J.M.3
Fitchett, D.4
Bluhmki, E.5
Hantel, S.6
-
13
-
-
85034766786
-
Canagliflozin and cardiovascular and renal events in type 2 diabetes
-
Neal B, Perkovic V, Mahaffey KW, de Zeeuw D, Fulcher G, Erondu N, et al. Canagliflozin and cardiovascular and renal events in type 2 diabetes. N Engl J Med. 2017;377:644-57.
-
(2017)
N Engl J Med
, vol.377
, pp. 644-657
-
-
Neal, B.1
Perkovic, V.2
Mahaffey, K.W.3
Zeeuw, D.4
Fulcher, G.5
Erondu, N.6
-
14
-
-
85019731757
-
Lower risk of heart failure and death in patients initiated on sodium-glucose cotransporter-2 inhibitors versus other glucose-lowering drugs: the CVD-REAL Study (comparative effectiveness of cardiovascular outcomes in new users of sodium-glucose cotransporter-2 inhibitors)
-
Kosiborod M, Cavender MA, Fu AZ, Wilding JP, Khunti K, Holl RW, et al. Lower risk of heart failure and death in patients initiated on sodium-glucose cotransporter-2 inhibitors versus other glucose-lowering drugs: the CVD-REAL Study (comparative effectiveness of cardiovascular outcomes in new users of sodium-glucose cotransporter-2 inhibitors). Circulation. 2017;136:249-59.
-
(2017)
Circulation
, vol.136
, pp. 249-259
-
-
Kosiborod, M.1
Cavender, M.A.2
Fu, A.Z.3
Wilding, J.P.4
Khunti, K.5
Holl, R.W.6
-
15
-
-
85026451851
-
Heart failure hospitalization risk associated with use of two classes of oral antidiabetic medications: an observational, real-world analysis
-
Gautam S, Agiro A, Barron J, Power T, Weisman H, White J. Heart failure hospitalization risk associated with use of two classes of oral antidiabetic medications: an observational, real-world analysis. Cardiovasc Diabetol. 2017;16:93.
-
(2017)
Cardiovasc Diabetol.
, vol.16
, pp. 93
-
-
Gautam, S.1
Agiro, A.2
Barron, J.3
Power, T.4
Weisman, H.5
White, J.6
-
16
-
-
85028684244
-
New antihyperglycemic drugs and heart failure: synopsis of basic and clinical data
-
von Lewinski D, Kolesnik E, Wallner M, Resl M, Sourij H. New antihyperglycemic drugs and heart failure: synopsis of basic and clinical data. Biomed Res Int. 2017;2017:1253425.
-
(2017)
Biomed Res Int
, vol.2017
, pp. 1253425
-
-
Lewinski, D.1
Kolesnik, E.2
Wallner, M.3
Resl, M.4
Sourij, H.5
-
17
-
-
85042008156
-
DECLARE-TIMI 58: participants' baseline characteristics
-
Raz I, Mosenzon O, Bonaca MP, Cahn A, Kato ET, Silverman MG, et al. DECLARE-TIMI 58: participants' baseline characteristics. Diab Obes Metab. 2018;20:1102-10.
-
(2018)
Diab Obes Metab
, vol.20
, pp. 1102-1110
-
-
Raz, I.1
Mosenzon, O.2
Bonaca, M.P.3
Cahn, A.4
Kato, E.T.5
Silverman, M.G.6
-
18
-
-
85031929302
-
Renal and Cardiovascular Effects of Sodium-Glucose cotransporter 2 (SGLT2) inhibition in combination with loop Diuretics in diabetic patients with Chronic Heart Failure (RECEDE-CHF): protocol for a randomised controlled double-blind cross-over trial
-
Mordi NA, Mordi IR, Singh JS, Baig F, Choy A-M, McCrimmon RJ, et al. Renal and Cardiovascular Effects of Sodium-Glucose cotransporter 2 (SGLT2) inhibition in combination with loop Diuretics in diabetic patients with Chronic Heart Failure (RECEDE-CHF): protocol for a randomised controlled double-blind cross-over trial. BMJ Open. 2017;7:e018097.
-
(2017)
BMJ Open
, vol.7
-
-
Mordi, N.A.1
Mordi, I.R.2
Singh, J.S.3
Baig, F.4
Choy, A.-M.5
McCrimmon, R.J.6
-
19
-
-
85009460363
-
Emerging roles of sodium-glucose cotransporter 2 inhibitors in cardiology
-
Tanaka A, Node K. Emerging roles of sodium-glucose cotransporter 2 inhibitors in cardiology. J Cardiol. 2017;69:501-7.
-
(2017)
J Cardiol
, vol.69
, pp. 501-507
-
-
Tanaka, A.1
Node, K.2
-
20
-
-
84964489933
-
Sodium-glucose cotransporter 2 inhibition and cardiovascular risk reduction in patients with type 2 diabetes: the emerging role of natriuresis
-
Rajasekeran H, Lytvyn Y, Cherney DZI. Sodium-glucose cotransporter 2 inhibition and cardiovascular risk reduction in patients with type 2 diabetes: the emerging role of natriuresis. Kidney Int. 2016;89:524-6.
-
(2016)
Kidney Int
, vol.89
, pp. 524-526
-
-
Rajasekeran, H.1
Lytvyn, Y.2
Cherney, D.Z.I.3
-
21
-
-
84964773926
-
SGLT2 inhibitors and cardiovascular risk: lessons learned from the EMPA-REG OUTCOME study
-
Abdul-Ghani M, Del Prato S, Chilton R, DeFronzo RA. SGLT2 inhibitors and cardiovascular risk: lessons learned from the EMPA-REG OUTCOME study. Diab Care. 2016;39:717-25.
-
(2016)
Diab Care
, vol.39
, pp. 717-725
-
-
Abdul-Ghani, M.1
Prato, S.2
Chilton, R.3
DeFronzo, R.A.4
-
22
-
-
84980320178
-
Sodium glucose cotransporter 2 inhibitors in the treatment of diabetes mellitus: cardiovascular and kidney effects, potential mechanisms, and clinical applications
-
Heerspink HJL, Perkins BA, Fitchett DH, Husain M, Cherney DZI. Sodium glucose cotransporter 2 inhibitors in the treatment of diabetes mellitus: cardiovascular and kidney effects, potential mechanisms, and clinical applications. Circulation. 2016;134:752-72.
-
(2016)
Circulation
, vol.134
, pp. 752-772
-
-
Heerspink, H.J.L.1
Perkins, B.A.2
Fitchett, D.H.3
Husain, M.4
Cherney, D.Z.I.5
-
23
-
-
85015765803
-
Sodium-glucose cotransporter-2 inhibition for the reduction of cardiovascular events in high-risk patients with diabetes mellitus
-
Marx N, McGuire DK. Sodium-glucose cotransporter-2 inhibition for the reduction of cardiovascular events in high-risk patients with diabetes mellitus. Eur Heart J. 2016;37:3192-200.
-
(2016)
Eur Heart J
, vol.37
, pp. 3192-3200
-
-
Marx, N.1
McGuire, D.K.2
-
24
-
-
84898854471
-
Effects of sodium-glucose co-transporter 2 inhibitors on blood pressure: a systematic review and meta-analysis
-
275.
-
Baker WL, Smyth LR, Riche DM, Bourret EM, Chamberlin KW, White WB. Effects of sodium-glucose co-transporter 2 inhibitors on blood pressure: a systematic review and meta-analysis. J Am Soc Hypertens JASH. 2014;8(262-275):e9.
-
(2014)
J Am Soc Hypertens JASH.
, vol.8
, Issue.262
-
-
Baker, W.L.1
Smyth, L.R.2
Riche, D.M.3
Bourret, E.M.4
Chamberlin, K.W.5
White, W.B.6
-
25
-
-
85020460150
-
Effect of sodium-glucose cotransport-2 inhibitors on blood pressure in people with type 2 diabetes mellitus: a systematic review and meta-analysis of 43 randomized control trials with 22 528 patients
-
Mazidi M, Rezaie P, Gao H-K, Kengne AP. Effect of sodium-glucose cotransport-2 inhibitors on blood pressure in people with type 2 diabetes mellitus: a systematic review and meta-analysis of 43 randomized control trials with 22 528 patients. J Am Heart Assoc. 2017;6:e004007.
-
(2017)
J Am Heart Assoc.
, vol.6
-
-
Mazidi, M.1
Rezaie, P.2
Gao, H.-K.3
Kengne, A.P.4
-
26
-
-
85019390334
-
Effects of sodium-glucose cotransporter 2 inhibitors on 24-hour ambulatory blood pressure: a systematic review and meta-analysis
-
Baker WL, Buckley LF, Kelly MS, Bucheit JD, Parod ED, Brown R, et al. Effects of sodium-glucose cotransporter 2 inhibitors on 24-hour ambulatory blood pressure: a systematic review and meta-analysis. J Am Heart Assoc. 2017;6:e005686.
-
(2017)
J Am Heart Assoc.
, vol.6
-
-
Baker, W.L.1
Buckley, L.F.2
Kelly, M.S.3
Bucheit, J.D.4
Parod, E.D.5
Brown, R.6
-
27
-
-
84880850027
-
Dapagliflozin a glucose-regulating drug with diuretic properties in subjects with type 2 diabetes
-
Lambers Heerspink HJ, de Zeeuw D, Wie L, Leslie B, List J. Dapagliflozin a glucose-regulating drug with diuretic properties in subjects with type 2 diabetes. Diab Obes Metab. 2013;15:853-62.
-
(2013)
Diab Obes Metab
, vol.15
, pp. 853-862
-
-
Lambers Heerspink, H.J.1
Zeeuw, D.2
Wie, L.3
Leslie, B.4
List, J.5
-
28
-
-
84945455839
-
Effects of empagliflozin on blood pressure and markers of arterial stiffness and vascular resistance in patients with type 2 diabetes
-
Chilton R, Tikkanen I, Cannon CP, Crowe S, Woerle HJ, Broedl UC, et al. Effects of empagliflozin on blood pressure and markers of arterial stiffness and vascular resistance in patients with type 2 diabetes. Diab Obes Metab. 2015;17:1180-93.
-
(2015)
Diab Obes Metab
, vol.17
, pp. 1180-1193
-
-
Chilton, R.1
Tikkanen, I.2
Cannon, C.P.3
Crowe, S.4
Woerle, H.J.5
Broedl, U.C.6
-
29
-
-
84892959743
-
The effect of empagliflozin on arterial stiffness and heart rate variability in subjects with uncomplicated type 1 diabetes mellitus
-
Cherney DZ, Perkins BA, Soleymanlou N, Har R, Fagan N, Johansen OE, et al. The effect of empagliflozin on arterial stiffness and heart rate variability in subjects with uncomplicated type 1 diabetes mellitus. Cardiovasc Diabetol. 2014;13:28.
-
(2014)
Cardiovasc Diabetol.
, vol.13
, pp. 28
-
-
Cherney, D.Z.1
Perkins, B.A.2
Soleymanlou, N.3
Har, R.4
Fagan, N.5
Johansen, O.E.6
-
30
-
-
84892588641
-
SGLT2 inhibitor empagliflozin reduces renal growth and albuminuria in proportion to hyperglycemia and prevents glomerular hyperfiltration in diabetic Akita mice
-
Vallon V, Gerasimova M, Rose MA, Masuda T, Satriano J, Mayoux E, et al. SGLT2 inhibitor empagliflozin reduces renal growth and albuminuria in proportion to hyperglycemia and prevents glomerular hyperfiltration in diabetic Akita mice. Am J Physiol Renal Physiol. 2014;306:F194-204.
-
(2014)
Am J Physiol Renal Physiol
, vol.306
-
-
Vallon, V.1
Gerasimova, M.2
Rose, M.A.3
Masuda, T.4
Satriano, J.5
Mayoux, E.6
-
31
-
-
84975153660
-
The effect of sodium glucose cotransporter 2 inhibition with empagliflozin on microalbuminuria and macroalbuminuria in patients with type 2 diabetes
-
Cherney D, Lund SS, Perkins BA, Groop P-H, Cooper ME, Kaspers S, et al. The effect of sodium glucose cotransporter 2 inhibition with empagliflozin on microalbuminuria and macroalbuminuria in patients with type 2 diabetes. Diabetologia. 2016;59:1860-70.
-
(2016)
Diabetologia
, vol.59
, pp. 1860-1870
-
-
Cherney, D.1
Lund, S.S.2
Perkins, B.A.3
Groop, P.-H.4
Cooper, M.E.5
Kaspers, S.6
-
32
-
-
84893214045
-
Renal hemodynamic effect of sodium-glucose cotransporter 2 inhibition in patients with type 1 diabetes mellitus
-
Cherney DZI, Perkins BA, Soleymanlou N, Maione M, Lai V, Lee A, et al. Renal hemodynamic effect of sodium-glucose cotransporter 2 inhibition in patients with type 1 diabetes mellitus. Circulation. 2014;129:587-97.
-
(2014)
Circulation
, vol.129
, pp. 587-597
-
-
Cherney, D.Z.I.1
Perkins, B.A.2
Soleymanlou, N.3
Maione, M.4
Lai, V.5
Lee, A.6
-
33
-
-
84893872877
-
Metabolic response to sodium-glucose cotransporter 2 inhibition in type 2 diabetic patients
-
Ferrannini E, Muscelli E, Frascerra S, Baldi S, Mari A, Heise T, et al. Metabolic response to sodium-glucose cotransporter 2 inhibition in type 2 diabetic patients. J Clin Invest. 2014;124:499-508.
-
(2014)
J Clin Invest.
, vol.124
, pp. 499-508
-
-
Ferrannini, E.1
Muscelli, E.2
Frascerra, S.3
Baldi, S.4
Mari, A.5
Heise, T.6
-
34
-
-
84893827104
-
Dapagliflozin improves muscle insulin sensitivity but enhances endogenous glucose production
-
Merovci A, Solis-Herrera C, Daniele G, Eldor R, Fiorentino TV, Tripathy D, et al. Dapagliflozin improves muscle insulin sensitivity but enhances endogenous glucose production. J Clin Invest. 2014;124:509-14.
-
(2014)
J Clin Invest.
, vol.124
, pp. 509-514
-
-
Merovci, A.1
Solis-Herrera, C.2
Daniele, G.3
Eldor, R.4
Fiorentino, T.V.5
Tripathy, D.6
-
35
-
-
84937763347
-
Inhibition of the glucose transporter SGLT2 with dapagliflozin in pancreatic alpha cells triggers glucagon secretion
-
Bonner C, Kerr-Conte J, Gmyr V, Queniat G, Moerman E, Thévenet J, et al. Inhibition of the glucose transporter SGLT2 with dapagliflozin in pancreatic alpha cells triggers glucagon secretion. Nat Med. 2015;21:512-7.
-
(2015)
Nat Med
, vol.21
, pp. 512-517
-
-
Bonner, C.1
Kerr-Conte, J.2
Gmyr, V.3
Queniat, G.4
Moerman, E.5
Thévenet, J.6
-
36
-
-
0023090430
-
Regulation of hepatic glucose metabolism in humans
-
DeFronzo RA, Ferrannini E. Regulation of hepatic glucose metabolism in humans. Diab Metab Rev. 1987;3:415-59.
-
(1987)
Diab Metab Rev
, vol.3
, pp. 415-459
-
-
DeFronzo, R.A.1
Ferrannini, E.2
-
37
-
-
0036737543
-
Glucagon dose-response curve for hepatic glucose production and glucose disposal in type 2 diabetic patients and normal individuals
-
Matsuda M, Defronzo RA, Glass L, Consoli A, Giordano M, Bressler P, et al. Glucagon dose-response curve for hepatic glucose production and glucose disposal in type 2 diabetic patients and normal individuals. Metabolism. 2002;51:1111-9.
-
(2002)
Metabolism.
, vol.51
, pp. 1111-1119
-
-
Matsuda, M.1
Defronzo, R.A.2
Glass, L.3
Consoli, A.4
Giordano, M.5
Bressler, P.6
-
38
-
-
0016834589
-
Glucagon regulation of plasma ketone body concentration in human diabetes
-
Schade DS, Eaton RP. Glucagon regulation of plasma ketone body concentration in human diabetes. J Clin Invest. 1975;56:1340-4.
-
(1975)
J Clin Invest.
, vol.56
, pp. 1340-1344
-
-
Schade, D.S.1
Eaton, R.P.2
-
39
-
-
0020567452
-
Role of glucagon in enhancing ketone body production in ketotic diabetic man
-
Keller U, Schnell H, Sonnenberg GE, Gerber PP, Stauffacher W. Role of glucagon in enhancing ketone body production in ketotic diabetic man. Diabetes. 1983;32:387-91.
-
(1983)
Diabetes
, vol.32
, pp. 387-391
-
-
Keller, U.1
Schnell, H.2
Sonnenberg, G.E.3
Gerber, P.P.4
Stauffacher, W.5
-
41
-
-
84921892213
-
Cardiomyocyte glucagon receptor signaling modulates outcomes in mice with experimental myocardial infarction
-
Ali S, Ussher JR, Baggio LL, Kabir MG, Charron MJ, Ilkayeva O, et al. Cardiomyocyte glucagon receptor signaling modulates outcomes in mice with experimental myocardial infarction. Mol Metab. 2015;4:132-43.
-
(2015)
Mol Metab.
, vol.4
, pp. 132-143
-
-
Ali, S.1
Ussher, J.R.2
Baggio, L.L.3
Kabir, M.G.4
Charron, M.J.5
Ilkayeva, O.6
-
42
-
-
84964608804
-
Shift to fatty substrate utilization in response to sodium-glucose cotransporter 2 inhibition in subjects without diabetes and patients with type 2 diabetes
-
Ferrannini E, Baldi S, Frascerra S, Astiarraga B, Heise T, Bizzotto R, et al. Shift to fatty substrate utilization in response to sodium-glucose cotransporter 2 inhibition in subjects without diabetes and patients with type 2 diabetes. Diabetes. 2016;65:1190-5.
-
(2016)
Diabetes
, vol.65
, pp. 1190-1195
-
-
Ferrannini, E.1
Baldi, S.2
Frascerra, S.3
Astiarraga, B.4
Heise, T.5
Bizzotto, R.6
-
43
-
-
84864371186
-
Weight loss induced by chronic dapagliflozin treatment is attenuated by compensatory hyperphagia in diet-induced obese (DIO) rats
-
Devenny JJ, Godonis HE, Harvey SJ, Rooney S, Cullen MJ, Pelleymounter MA. Weight loss induced by chronic dapagliflozin treatment is attenuated by compensatory hyperphagia in diet-induced obese (DIO) rats. Obes Silver Spring Md. 2012;20:1645-52.
-
(2012)
Obes Silver Spring Md.
, vol.20
, pp. 1645-1652
-
-
Devenny, J.J.1
Godonis, H.E.2
Harvey, S.J.3
Rooney, S.4
Cullen, M.J.5
Pelleymounter, M.A.6
-
44
-
-
84905446525
-
Tofogliflozin, a sodium/glucose cotransporter 2 inhibitor, attenuates body weight gain and fat accumulation in diabetic and obese animal models
-
Suzuki M, Takeda M, Kito A, Fukazawa M, Yata T, Yamamoto M, et al. Tofogliflozin, a sodium/glucose cotransporter 2 inhibitor, attenuates body weight gain and fat accumulation in diabetic and obese animal models. Nutr Diab. 2014;4:e125.
-
(2014)
Nutr Diab
, vol.4
-
-
Suzuki, M.1
Takeda, M.2
Kito, A.3
Fukazawa, M.4
Yata, T.5
Yamamoto, M.6
-
47
-
-
83455179322
-
Altered systemic ketone body metabolism in advanced heart failure
-
Janardhan A, Chen J, Crawford PA. Altered systemic ketone body metabolism in advanced heart failure. Tex Heart Inst J. 2011;38:533-8.
-
(2011)
Tex Heart Inst J
, vol.38
, pp. 533-538
-
-
Janardhan, A.1
Chen, J.2
Crawford, P.A.3
-
48
-
-
84975775560
-
The failing heart relies on ketone bodies as a fuel
-
Aubert G, Martin OJ, Horton JL, Lai L, Vega RB, Leone TC, et al. The failing heart relies on ketone bodies as a fuel. Circulation. 2016;133:698-705.
-
(2016)
Circulation
, vol.133
, pp. 698-705
-
-
Aubert, G.1
Martin, O.J.2
Horton, J.L.3
Lai, L.4
Vega, R.B.5
Leone, T.C.6
-
49
-
-
84873842388
-
Short-term fasting reduces the extent of myocardial infarction and incidence of reperfusion arrhythmias in rats
-
Snorek M, Hodyc D, Sedivý V, Durišová J, Skoumalová A, Wilhelm J, et al. Short-term fasting reduces the extent of myocardial infarction and incidence of reperfusion arrhythmias in rats. Physiol Res. 2012;61:567-74.
-
(2012)
Physiol Res
, vol.61
, pp. 567-574
-
-
Snorek, M.1
Hodyc, D.2
Sedivý, V.3
Durišová, J.4
Skoumalová, A.5
Wilhelm, J.6
-
50
-
-
84861764348
-
Mitochondrial biogenesis and increased uncoupling protein 1 in brown adipose tissue of mice fed a ketone ester diet
-
Srivastava S, Kashiwaya Y, King MT, Baxa U, Tam J, Niu G, et al. Mitochondrial biogenesis and increased uncoupling protein 1 in brown adipose tissue of mice fed a ketone ester diet. FASEB J Off Publ Fed Am Soc Exp Biol. 2012;26:2351-62.
-
(2012)
FASEB J Off Publ Fed Am Soc Exp Biol.
, vol.26
, pp. 2351-2362
-
-
Srivastava, S.1
Kashiwaya, Y.2
King, M.T.3
Baxa, U.4
Tam, J.5
Niu, G.6
-
51
-
-
84975853831
-
CV protection in the EMPA-REG OUTCOME trial: a "Thrifty Substrate" hypothesis
-
Ferrannini E, Mark M, Mayoux E. CV protection in the EMPA-REG OUTCOME trial: a "Thrifty Substrate" hypothesis. Diab Care. 2016;39:1108-14.
-
(2016)
Diab Care
, vol.39
, pp. 1108-1114
-
-
Ferrannini, E.1
Mark, M.2
Mayoux, E.3
-
52
-
-
84958158486
-
Empagliflozin reduces body weight and indices of adipose distribution in patients with type 2 diabetes mellitus
-
Neeland IJ, McGuire DK, Chilton R, Crowe S, Lund SS, Woerle HJ, et al. Empagliflozin reduces body weight and indices of adipose distribution in patients with type 2 diabetes mellitus. Diab Vasc Dis Res. 2016;13:119-26.
-
(2016)
Diab Vasc Dis Res.
, vol.13
, pp. 119-126
-
-
Neeland, I.J.1
McGuire, D.K.2
Chilton, R.3
Crowe, S.4
Lund, S.S.5
Woerle, H.J.6
-
53
-
-
84858020943
-
Effects of dapagliflozin on body weight, total fat mass, and regional adipose tissue distribution in patients with type 2 diabetes mellitus with inadequate glycemic control on metformin
-
Bolinder J, Ljunggren Ö, Kullberg J, Johansson L, Wilding J, Langkilde AM, et al. Effects of dapagliflozin on body weight, total fat mass, and regional adipose tissue distribution in patients with type 2 diabetes mellitus with inadequate glycemic control on metformin. J Clin Endocrinol Metab. 2012;97:1020-31.
-
(2012)
J Clin Endocrinol Metab
, vol.97
, pp. 1020-1031
-
-
Bolinder, J.1
Ljunggren, O.2
Kullberg, J.3
Johansson, L.4
Wilding, J.5
Langkilde, A.M.6
-
54
-
-
84893682957
-
SGLT2 selective inhibitor ipragliflozin reduces body fat mass by increasing fatty acid oxidation in high-fat diet-induced obese rats
-
Yokono M, Takasu T, Hayashizaki Y, Mitsuoka K, Kihara R, Muramatsu Y, et al. SGLT2 selective inhibitor ipragliflozin reduces body fat mass by increasing fatty acid oxidation in high-fat diet-induced obese rats. Eur J Pharmacol. 2014;727:66-74.
-
(2014)
Eur J Pharmacol
, vol.727
, pp. 66-74
-
-
Yokono, M.1
Takasu, T.2
Hayashizaki, Y.3
Mitsuoka, K.4
Kihara, R.5
Muramatsu, Y.6
-
55
-
-
0141640818
-
Human cardiomyocytes express high level of Na+/glucose cotransporter 1 (SGLT1)
-
Zhou L, Cryan EV, D'Andrea MR, Belkowski S, Conway BR, Demarest KT. Human cardiomyocytes express high level of Na+/glucose cotransporter 1 (SGLT1). J Cell Biochem. 2003;90:339-46.
-
(2003)
J Cell Biochem
, vol.90
, pp. 339-346
-
-
Zhou, L.1
Cryan, E.V.2
D'Andrea, M.R.3
Belkowski, S.4
Conway, B.R.5
Demarest, K.T.6
-
56
-
-
79952721660
-
Quantitative PCR tissue expression profiling of the human SGLT2 gene and related family members
-
Chen J, Williams S, Ho S, Loraine H, Hagan D, Whaley JM, et al. Quantitative PCR tissue expression profiling of the human SGLT2 gene and related family members. Diab Ther. 2010;1:57-92.
-
(2010)
Diab Ther.
, vol.1
, pp. 57-92
-
-
Chen, J.1
Williams, S.2
Ho, S.3
Loraine, H.4
Hagan, D.5
Whaley, J.M.6
-
57
-
-
84995969879
-
Empagliflozin lessened cardiac injury and reduced visceral adipocyte hypertrophy in prediabetic rats with metabolic syndrome
-
Kusaka H, Koibuchi N, Hasegawa Y, Ogawa H, Kim-Mitsuyama S. Empagliflozin lessened cardiac injury and reduced visceral adipocyte hypertrophy in prediabetic rats with metabolic syndrome. Cardiovasc Diabetol. 2016;15:157.
-
(2016)
Cardiovasc Diabetol.
, vol.15
, pp. 157
-
-
Kusaka, H.1
Koibuchi, N.2
Hasegawa, Y.3
Ogawa, H.4
Kim-Mitsuyama, S.5
-
58
-
-
84964696031
-
Glycemic control with empagliflozin, a novel selective SGLT2 inhibitor, ameliorates cardiovascular injury and cognitive dysfunction in obese and type 2 diabetic mice
-
Lin B, Koibuchi N, Hasegawa Y, Sueta D, Toyama K, Uekawa K, et al. Glycemic control with empagliflozin, a novel selective SGLT2 inhibitor, ameliorates cardiovascular injury and cognitive dysfunction in obese and type 2 diabetic mice. Cardiovasc Diabetol. 2014;13:148.
-
(2014)
Cardiovasc Diabetol.
, vol.13
, pp. 148
-
-
Lin, B.1
Koibuchi, N.2
Hasegawa, Y.3
Sueta, D.4
Toyama, K.5
Uekawa, K.6
-
59
-
-
85010216514
-
Sodium glucose transporter 2 (SGLT2) inhibition with empagliflozin improves cardiac diastolic function in a female rodent model of diabetes
-
Habibi J, Aroor AR, Sowers JR, Jia G, Hayden MR, Garro M, et al. Sodium glucose transporter 2 (SGLT2) inhibition with empagliflozin improves cardiac diastolic function in a female rodent model of diabetes. Cardiovasc Diabetol. 2017;16:9.
-
(2017)
Cardiovasc Diabetol.
, vol.16
, pp. 9
-
-
Habibi, J.1
Aroor, A.R.2
Sowers, J.R.3
Jia, G.4
Hayden, M.R.5
Garro, M.6
-
60
-
-
85021069048
-
Empagliflozin improves left ventricular diastolic dysfunction in a genetic model of type 2 diabetes
-
Hammoudi N, Jeong D, Singh R, Farhat A, Komajda M, Mayoux E, et al. Empagliflozin improves left ventricular diastolic dysfunction in a genetic model of type 2 diabetes. Cardiovasc Drugs Ther. 2017;31:233-46.
-
(2017)
Cardiovasc Drugs Ther
, vol.31
, pp. 233-246
-
-
Hammoudi, N.1
Jeong, D.2
Singh, R.3
Farhat, A.4
Komajda, M.5
Mayoux, E.6
-
61
-
-
0034456976
-
Insulin receptor substrate-1-mediated enhancement of growth hormone-induced mitogen-activated protein kinase activation
-
Liang L, Jiang J, Frank SJ. Insulin receptor substrate-1-mediated enhancement of growth hormone-induced mitogen-activated protein kinase activation. Endocrinology. 2000;141:3328-36.
-
(2000)
Endocrinology
, vol.141
, pp. 3328-3336
-
-
Liang, L.1
Jiang, J.2
Frank, S.J.3
-
62
-
-
85021278361
-
The sodium-glucose co-transporter 2 inhibitor, empagliflozin, protects against diabetic cardiomyopathy by inhibition of the endoplasmic reticulum stress pathway
-
Zhou Y, Wu W. The sodium-glucose co-transporter 2 inhibitor, empagliflozin, protects against diabetic cardiomyopathy by inhibition of the endoplasmic reticulum stress pathway. Cell Physiol Biochem Int J Exp Cell Physiol Biochem Pharmacol. 2017;41:2503-12.
-
(2017)
Cell Physiol Biochem Int J Exp Cell Physiol Biochem Pharmacol.
, vol.41
, pp. 2503-2512
-
-
Zhou, Y.1
Wu, W.2
-
63
-
-
85018253813
-
SGLT-2 inhibition with dapagliflozin reduces the activation of the Nlrp3/ASC inflammasome and attenuates the development of diabetic cardiomyopathy in mice with type 2 diabetes. further augmentation of the effects with saxagliptin, a DPP4 inhibitor
-
Ye Y, Bajaj M, Yang H-C, Perez-Polo JR, Birnbaum Y. SGLT-2 inhibition with dapagliflozin reduces the activation of the Nlrp3/ASC inflammasome and attenuates the development of diabetic cardiomyopathy in mice with type 2 diabetes. further augmentation of the effects with saxagliptin, a DPP4 inhibitor. Cardiovasc Drugs Ther. 2017;31:119-32.
-
(2017)
Cardiovasc Drugs Ther
, vol.31
, pp. 119-132
-
-
Ye, Y.1
Bajaj, M.2
Yang, H.-C.3
Perez-Polo, J.R.4
Birnbaum, Y.5
-
64
-
-
85042119123
-
Cardioprotection of dapagliflozin and vildagliptin in rats with cardiac ischemia-reperfusion injury
-
Tanajak P, Sa-Nguanmoo P, Sivasinprasasn S, Thummasorn S, Siri-Angkul N, Chattipakorn SC, et al. Cardioprotection of dapagliflozin and vildagliptin in rats with cardiac ischemia-reperfusion injury. J Endocrinol. 2018;236:69-84.
-
(2018)
J Endocrinol
, vol.236
, pp. 69-84
-
-
Tanajak, P.1
Sa-Nguanmoo, P.2
Sivasinprasasn, S.3
Thummasorn, S.4
Siri-Angkul, N.5
Chattipakorn, S.C.6
-
65
-
-
85010842028
-
Dapagliflozin, a selective SGLT2 Inhibitor, attenuated cardiac fibrosis by regulating the macrophage polarization via STAT3 signaling in infarcted rat hearts
-
Lee T-M, Chang N-C, Lin S-Z. Dapagliflozin, a selective SGLT2 Inhibitor, attenuated cardiac fibrosis by regulating the macrophage polarization via STAT3 signaling in infarcted rat hearts. Free Radic Biol Med. 2017;104:298-310.
-
(2017)
Free Radic Biol Med.
, vol.104
, pp. 298-310
-
-
Lee, T.-M.1
Chang, N.-C.2
Lin, S.-Z.3
-
66
-
-
85017099681
-
Effect of empagliflozin on cardiac biomarkers in a zebrafish model of heart failure: clues to the EMPA-REG OUTCOME trial?
-
Shi X, Verma S, Yun J, Brand-Arzamendi K, Singh KK, Liu X, et al. Effect of empagliflozin on cardiac biomarkers in a zebrafish model of heart failure: clues to the EMPA-REG OUTCOME trial? Mol Cell Biochem. 2017;433:97-102.
-
(2017)
Mol Cell Biochem
, vol.433
, pp. 97-102
-
-
Shi, X.1
Verma, S.2
Yun, J.3
Brand-Arzamendi, K.4
Singh, K.K.5
Liu, X.6
-
67
-
-
84890936239
-
Zebrafish heart failure models for the evaluation of chemical probes and drugs
-
Huang C-C, Monte A, Cook JM, Kabir MS, Peterson KP. Zebrafish heart failure models for the evaluation of chemical probes and drugs. Assay Drug Dev Technol. 2013;11:561-72.
-
(2013)
Assay Drug Dev Technol
, vol.11
, pp. 561-572
-
-
Huang, C.-C.1
Monte, A.2
Cook, J.M.3
Kabir, M.S.4
Peterson, K.P.5
-
68
-
-
85025091208
-
Effects of canagliflozin on cardiovascular biomarkers in older adults with type 2 diabetes
-
Januzzi JL, Butler J, Jarolim P, Sattar N, Vijapurkar U, Desai M, et al. Effects of canagliflozin on cardiovascular biomarkers in older adults with type 2 diabetes. J Am Coll Cardiol. 2017;70:704-12.
-
(2017)
J Am Coll Cardiol
, vol.70
, pp. 704-712
-
-
Januzzi, J.L.1
Butler, J.2
Jarolim, P.3
Sattar, N.4
Vijapurkar, U.5
Desai, M.6
-
69
-
-
85019618220
-
The sodium-glucose cotransporter 2 inhibitor dapagliflozin prevents cardiomyopathy in a diabetic lipodystrophic mouse model
-
Joubert M, Jagu B, Montaigne D, Marechal X, Tesse A, Ayer A, et al. The sodium-glucose cotransporter 2 inhibitor dapagliflozin prevents cardiomyopathy in a diabetic lipodystrophic mouse model. Diabetes. 2017;66:1030-40.
-
(2017)
Diabetes
, vol.66
, pp. 1030-1040
-
-
Joubert, M.1
Jagu, B.2
Montaigne, D.3
Marechal, X.4
Tesse, A.5
Ayer, A.6
-
70
-
-
85026780953
-
Effect of sodium-glucose co-transporter-2 inhibitors on impaired ventricular repolarization in people with Type 2 diabetes
-
Sato T, Miki T, Ohnishi H, Yamashita T, Takada A, Yano T, et al. Effect of sodium-glucose co-transporter-2 inhibitors on impaired ventricular repolarization in people with Type 2 diabetes. Diab Med J Br Diab Assoc. 2017;34:1367-71.
-
(2017)
Diab Med J Br Diab Assoc.
, vol.34
, pp. 1367-1371
-
-
Sato, T.1
Miki, T.2
Ohnishi, H.3
Yamashita, T.4
Takada, A.5
Yano, T.6
-
72
-
-
79960920271
-
NLRP3 inflammasomes link inflammation and metabolic disease
-
De Nardo D, Latz E. NLRP3 inflammasomes link inflammation and metabolic disease. Trends Immunol. 2011;32:373-9.
-
(2011)
Trends Immunol
, vol.32
, pp. 373-379
-
-
Nardo, D.1
Latz, E.2
-
73
-
-
84872014417
-
Nlrp3 inflammasome activation in type 2 diabetes: is it clinically relevant?
-
Dixit VD. Nlrp3 inflammasome activation in type 2 diabetes: is it clinically relevant? Diabetes. 2013;62:22-4.
-
(2013)
Diabetes
, vol.62
, pp. 22-24
-
-
Dixit, V.D.1
-
74
-
-
0037265240
-
Alternative activation of macrophages
-
Gordon S. Alternative activation of macrophages. Nat Rev Immunol. 2003;3:23-35.
-
(2003)
Nat Rev Immunol
, vol.3
, pp. 23-35
-
-
Gordon, S.1
-
75
-
-
77956958947
-
Activation of the NLRP3 inflammasome by islet amyloid polypeptide provides a mechanism for enhanced IL-1β in type 2 diabetes
-
Masters SL, Dunne A, Subramanian SL, Hull RL, Tannahill GM, Sharp FA, et al. Activation of the NLRP3 inflammasome by islet amyloid polypeptide provides a mechanism for enhanced IL-1β in type 2 diabetes. Nat Immunol. 2010;11:897-904.
-
(2010)
Nat Immunol
, vol.11
, pp. 897-904
-
-
Masters, S.L.1
Dunne, A.2
Subramanian, S.L.3
Hull, R.L.4
Tannahill, G.M.5
Sharp, F.A.6
-
76
-
-
84872018875
-
Upregulated NLRP3 inflammasome activation in patients with type 2 diabetes
-
Lee H-M, Kim J-J, Kim HJ, Shong M, Ku BJ, Jo E-K. Upregulated NLRP3 inflammasome activation in patients with type 2 diabetes. Diabetes. 2013;62:194-204.
-
(2013)
Diabetes
, vol.62
, pp. 194-204
-
-
Lee, H.-M.1
Kim, J.-J.2
Kim, H.J.3
Shong, M.4
Ku, B.J.5
Jo, E.-K.6
-
77
-
-
84897536939
-
Activation of toll-like receptors and inflammasome complexes in the diabetic cardiomyopathy-associated inflammation
-
Fuentes-Antrás J, Ioan AM, Tuñón J, Egido J, Lorenzo O. Activation of toll-like receptors and inflammasome complexes in the diabetic cardiomyopathy-associated inflammation. Int J Endocrinol. 2014;2014:847827.
-
(2014)
Int J Endocrinol.
, vol.2014
, pp. 847827
-
-
Fuentes-Antrás, J.1
Ioan, A.M.2
Tuñón, J.3
Egido, J.4
Lorenzo, O.5
-
78
-
-
84927700592
-
NLRP3 gene silencing ameliorates diabetic cardiomyopathy in a type 2 diabetes rat model
-
Luo B, Li B, Wang W, Liu X, Xia Y, Zhang C, et al. NLRP3 gene silencing ameliorates diabetic cardiomyopathy in a type 2 diabetes rat model. PLoS ONE. 2014;9:e104771.
-
(2014)
PLoS ONE
, vol.9
-
-
Luo, B.1
Li, B.2
Wang, W.3
Liu, X.4
Xia, Y.5
Zhang, C.6
-
79
-
-
84898799055
-
The NLRP3 inflammasome and diabetic cardiomyopathy: editorial to: "Rosuvastatin alleviates diabetic cardiomyopathy by inhibiting NLRP3 inflammasome and MAPK pathways in a type 2 diabetes rat model" by Beibei Luo et al
-
Singh LP. The NLRP3 inflammasome and diabetic cardiomyopathy: editorial to: "Rosuvastatin alleviates diabetic cardiomyopathy by inhibiting NLRP3 inflammasome and MAPK pathways in a type 2 diabetes rat model" by Beibei Luo et al. Cardiovasc Drugs Ther. 2014;28:5-6.
-
(2014)
Cardiovasc Drugs Ther
, vol.28
, pp. 5-6
-
-
Singh, L.P.1
-
80
-
-
0034677947
-
NAD(P)H oxidase: role in cardiovascular biology and disease
-
Griendling KK, Sorescu D, Ushio-Fukai M. NAD(P)H oxidase: role in cardiovascular biology and disease. Circ Res. 2000;86:494-501.
-
(2000)
Circ Res
, vol.86
, pp. 494-501
-
-
Griendling, K.K.1
Sorescu, D.2
Ushio-Fukai, M.3
-
81
-
-
33846418746
-
Role of oxidative stress in cardiac hypertrophy and remodeling
-
Takimoto E, Kass DA. Role of oxidative stress in cardiac hypertrophy and remodeling. Hypertens Dallas Tex. 1979;2007(49):241-8.
-
(1979)
Hypertens Dallas Tex
, vol.2007
, Issue.49
, pp. 241-248
-
-
Takimoto, E.1
Kass, D.A.2
-
82
-
-
33748540075
-
Enhancement of cardiac oxidative stress by tachycardia and its critical role in cardiac hypertrophy and fibrosis
-
Yamamoto E, Lai Z-F, Yamashita T, Tanaka T, Kataoka K, Tokutomi Y, et al. Enhancement of cardiac oxidative stress by tachycardia and its critical role in cardiac hypertrophy and fibrosis. J Hypertens. 2006;24:2057-69.
-
(2006)
J Hypertens
, vol.24
, pp. 2057-2069
-
-
Yamamoto, E.1
Lai, Z.-F.2
Yamashita, T.3
Tanaka, T.4
Kataoka, K.5
Tokutomi, Y.6
-
83
-
-
84911942671
-
The sodium-glucose co-transporter 2 inhibitor empagliflozin improves diabetes-induced vascular dysfunction in the streptozotocin diabetes rat model by interfering with oxidative stress and glucotoxicity
-
Oelze M, Kröller-Schön S, Welschof P, Jansen T, Hausding M, Mikhed Y, et al. The sodium-glucose co-transporter 2 inhibitor empagliflozin improves diabetes-induced vascular dysfunction in the streptozotocin diabetes rat model by interfering with oxidative stress and glucotoxicity. PLoS ONE. 2014;9:e112394.
-
(2014)
PLoS ONE
, vol.9
-
-
Oelze, M.1
Kröller-Schön, S.2
Welschof, P.3
Jansen, T.4
Hausding, M.5
Mikhed, Y.6
-
84
-
-
84879473184
-
N-Acetylcysteine and allopurinol up-regulated the Jak/STAT3 and PI3K/Akt pathways via adiponectin and attenuated myocardial postischemic injury in diabetes
-
Wang T, Mao X, Li H, Qiao S, Xu A, Wang J, et al. N-Acetylcysteine and allopurinol up-regulated the Jak/STAT3 and PI3K/Akt pathways via adiponectin and attenuated myocardial postischemic injury in diabetes. Free Radic Biol Med. 2013;63:291-303.
-
(2013)
Free Radic Biol Med.
, vol.63
, pp. 291-303
-
-
Wang, T.1
Mao, X.2
Li, H.3
Qiao, S.4
Xu, A.5
Wang, J.6
-
85
-
-
84876569854
-
The heme oxygenase system selectively enhances the anti-inflammatory macrophage-M2 phenotype, reduces pericardial adiposity, and ameliorated cardiac injury in diabetic cardiomyopathy in Zucker diabetic fatty rats
-
Jadhav A, Tiwari S, Lee P, Ndisang JF. The heme oxygenase system selectively enhances the anti-inflammatory macrophage-M2 phenotype, reduces pericardial adiposity, and ameliorated cardiac injury in diabetic cardiomyopathy in Zucker diabetic fatty rats. J Pharmacol Exp Ther. 2013;345:239-49.
-
(2013)
J Pharmacol Exp Ther
, vol.345
, pp. 239-249
-
-
Jadhav, A.1
Tiwari, S.2
Lee, P.3
Ndisang, J.F.4
-
86
-
-
85008925639
-
Signaling pathways in cardiac myocyte apoptosis
-
Xia P, Liu Y, Cheng Z. Signaling pathways in cardiac myocyte apoptosis. Biomed Res Int. 2016;2016:9583268.
-
(2016)
Biomed Res Int
, vol.2016
-
-
Xia, P.1
Liu, Y.2
Cheng, Z.3
-
87
-
-
84883793281
-
Cardiomyocyte apoptosis in the failing heart-a critical review from definition and classification of cell death
-
Takemura G, Kanoh M, Minatoguchi S, Fujiwara H. Cardiomyocyte apoptosis in the failing heart-a critical review from definition and classification of cell death. Int J Cardiol. 2013;167:2373-86.
-
(2013)
Int J Cardiol
, vol.167
, pp. 2373-2386
-
-
Takemura, G.1
Kanoh, M.2
Minatoguchi, S.3
Fujiwara, H.4
-
88
-
-
33746325877
-
Morphological aspects of apoptosis in heart diseases
-
Takemura G, Fujiwara H. Morphological aspects of apoptosis in heart diseases. J Cell Mol Med. 2006;10:56-75.
-
(2006)
J Cell Mol Med
, vol.10
, pp. 56-75
-
-
Takemura, G.1
Fujiwara, H.2
-
89
-
-
84886730359
-
Protein kinase RNA-like endoplasmic reticulum kinase (PERK) signaling pathway plays a major role in reactive oxygen species (ROS)-mediated endoplasmic reticulum stress-induced apoptosis in diabetic cardiomyopathy
-
Liu Z-W, Zhu H-T, Chen K-L, Dong X, Wei J, Qiu C, et al. Protein kinase RNA-like endoplasmic reticulum kinase (PERK) signaling pathway plays a major role in reactive oxygen species (ROS)-mediated endoplasmic reticulum stress-induced apoptosis in diabetic cardiomyopathy. Cardiovasc Diabetol. 2013;12:158.
-
(2013)
Cardiovasc Diabetol.
, vol.12
, pp. 158
-
-
Liu, Z.-W.1
Zhu, H.-T.2
Chen, K.-L.3
Dong, X.4
Wei, J.5
Qiu, C.6
-
90
-
-
33748789479
-
Mediators of endoplasmic reticulum stress-induced apoptosis
-
Szegezdi E, Logue SE, Gorman AM, Samali A. Mediators of endoplasmic reticulum stress-induced apoptosis. EMBO Rep. 2006;7:880-5.
-
(2006)
EMBO Rep
, vol.7
, pp. 880-885
-
-
Szegezdi, E.1
Logue, S.E.2
Gorman, A.M.3
Samali, A.4
-
91
-
-
84896535965
-
Liraglutide alleviates diabetic cardiomyopathy by blocking CHOP-triggered apoptosis via the inhibition of the IRE-α pathway
-
Ji Y, Zhao Z, Cai T, Yang P, Cheng M. Liraglutide alleviates diabetic cardiomyopathy by blocking CHOP-triggered apoptosis via the inhibition of the IRE-α pathway. Mol Med Rep. 2014;9:1254-8.
-
(2014)
Mol Med Rep.
, vol.9
, pp. 1254-1258
-
-
Ji, Y.1
Zhao, Z.2
Cai, T.3
Yang, P.4
Cheng, M.5
-
92
-
-
79954632042
-
Valsartan protects against ER stress-induced myocardial apoptosis via CHOP/Puma signaling pathway in streptozotocin-induced diabetic rats
-
Wu T, Dong Z, Geng J, Sun Y, Liu G, Kang W, et al. Valsartan protects against ER stress-induced myocardial apoptosis via CHOP/Puma signaling pathway in streptozotocin-induced diabetic rats. Eur J Pharm Sci Off J Eur Fed Pharm Sci. 2011;42:496-502.
-
(2011)
Eur J Pharm Sci Off J Eur Fed Pharm Sci.
, vol.42
, pp. 496-502
-
-
Wu, T.1
Dong, Z.2
Geng, J.3
Sun, Y.4
Liu, G.5
Kang, W.6
-
93
-
-
0035966269
-
XBP1 mRNA is induced by ATF6 and spliced by IRE1 in response to ER stress to produce a highly active transcription factor
-
Yoshida H, Matsui T, Yamamoto A, Okada T, Mori K. XBP1 mRNA is induced by ATF6 and spliced by IRE1 in response to ER stress to produce a highly active transcription factor. Cell. 2001;107:881-91.
-
(2001)
Cell
, vol.107
, pp. 881-891
-
-
Yoshida, H.1
Matsui, T.2
Yamamoto, A.3
Okada, T.4
Mori, K.5
-
94
-
-
33745844503
-
Endoplasmic reticulum stress in health and disease
-
Zhao L, Ackerman SL. Endoplasmic reticulum stress in health and disease. Curr Opin Cell Biol. 2006;18:444-52.
-
(2006)
Curr Opin Cell Biol
, vol.18
, pp. 444-452
-
-
Zhao, L.1
Ackerman, S.L.2
-
95
-
-
84960807319
-
Inhibition of endoplasmic reticulum stress-activated IRE1α-TRAF2-caspase-12 apoptotic pathway is involved in the neuroprotective effects of telmisartan in the rotenone rat model of Parkinson's disease
-
Tong Q, Wu L, Jiang T, Ou Z, Zhang Y, Zhu D. Inhibition of endoplasmic reticulum stress-activated IRE1α-TRAF2-caspase-12 apoptotic pathway is involved in the neuroprotective effects of telmisartan in the rotenone rat model of Parkinson's disease. Eur J Pharmacol. 2016;776:106-15.
-
(2016)
Eur J Pharmacol
, vol.776
, pp. 106-115
-
-
Tong, Q.1
Wu, L.2
Jiang, T.3
Ou, Z.4
Zhang, Y.5
Zhu, D.6
-
96
-
-
27744500069
-
Endoplasmic reticulum stress-associated caspase 12 mediates cisplatin-induced LLC-PK1 cell apoptosis
-
Liu H, Baliga R. Endoplasmic reticulum stress-associated caspase 12 mediates cisplatin-induced LLC-PK1 cell apoptosis. J Am Soc Nephrol JASN. 2005;16:1985-92.
-
(2005)
J Am Soc Nephrol JASN.
, vol.16
, pp. 1985-1992
-
-
Liu, H.1
Baliga, R.2
-
97
-
-
79959408564
-
Attenuation of CHOP-mediated myocardial apoptosis in pressure-overloaded dominant negative p38α mitogen-activated protein kinase mice
-
Sari FR, Widyantoro B, Thandavarayan RA, Harima M, Lakshmanan AP, Zhang S, et al. Attenuation of CHOP-mediated myocardial apoptosis in pressure-overloaded dominant negative p38α mitogen-activated protein kinase mice. Cell Physiol Biochem Int J Exp Cell Physiol Biochem Pharmacol. 2011;27:487-96.
-
(2011)
Cell Physiol Biochem Int J Exp Cell Physiol Biochem Pharmacol.
, vol.27
, pp. 487-496
-
-
Sari, F.R.1
Widyantoro, B.2
Thandavarayan, R.A.3
Harima, M.4
Lakshmanan, A.P.5
Zhang, S.6
-
98
-
-
84961210563
-
Bis(maltolato)oxovanadium(IV) (BMOV) attenuates apoptosis in high glucose-treated cardiac cells and diabetic rat hearts by regulating the unfolded protein responses (UPRs)
-
Cong X-Q, Piao M-H, Li Y, Xie L, Liu Y. Bis(maltolato)oxovanadium(IV) (BMOV) attenuates apoptosis in high glucose-treated cardiac cells and diabetic rat hearts by regulating the unfolded protein responses (UPRs). Biol Trace Elem Res. 2016;173:390-8.
-
(2016)
Biol Trace Elem Res
, vol.173
, pp. 390-398
-
-
Cong, X.-Q.1
Piao, M.-H.2
Li, Y.3
Xie, L.4
Liu, Y.5
-
100
-
-
84930670567
-
Mitochondrial dynamics in diabetic cardiomyopathy
-
Galloway CA, Yoon Y. Mitochondrial dynamics in diabetic cardiomyopathy. Antioxid Redox Signal. 2015;22:1545-62.
-
(2015)
Antioxid Redox Signal
, vol.22
, pp. 1545-1562
-
-
Galloway, C.A.1
Yoon, Y.2
-
101
-
-
84906070274
-
Myocardial contractile dysfunction is associated with impaired mitochondrial function and dynamics in type 2 diabetic but not in obese patients
-
Montaigne D, Marechal X, Coisne A, Debry N, Modine T, Fayad G, et al. Myocardial contractile dysfunction is associated with impaired mitochondrial function and dynamics in type 2 diabetic but not in obese patients. Circulation. 2014;130:554-64.
-
(2014)
Circulation
, vol.130
, pp. 554-564
-
-
Montaigne, D.1
Marechal, X.2
Coisne, A.3
Debry, N.4
Modine, T.5
Fayad, G.6
-
102
-
-
84995366693
-
Obesity-induced cardiac lipid accumulation in adult mice is modulated by G protein-coupled receptor kinase 2 levels
-
Lucas E, Vila-Bedmar R, Arcones AC, Cruces-Sande M, Cachofeiro V, Mayor F, et al. Obesity-induced cardiac lipid accumulation in adult mice is modulated by G protein-coupled receptor kinase 2 levels. Cardiovasc Diabetol. 2016;15:155.
-
(2016)
Cardiovasc Diabetol.
, vol.15
, pp. 155
-
-
Lucas, E.1
Vila-Bedmar, R.2
Arcones, A.C.3
Cruces-Sande, M.4
Cachofeiro, V.5
Mayor, F.6
-
103
-
-
79953765816
-
Peroxisome proliferator activated receptor-alpha (PPARα) and PPAR gamma coactivator-1alpha (PGC-1α) regulation of cardiac metabolism in diabetes
-
Duncan JG. Peroxisome proliferator activated receptor-alpha (PPARα) and PPAR gamma coactivator-1alpha (PGC-1α) regulation of cardiac metabolism in diabetes. Pediatr Cardiol. 2011;32:323-8.
-
(2011)
Pediatr Cardiol
, vol.32
, pp. 323-328
-
-
Duncan, J.G.1
-
104
-
-
78649413837
-
Mitochondrial fusion and fission in cell life and death
-
Westermann B. Mitochondrial fusion and fission in cell life and death. Nat Rev Mol Cell Biol. 2010;11:872-84.
-
(2010)
Nat Rev Mol Cell Biol
, vol.11
, pp. 872-884
-
-
Westermann, B.1
-
105
-
-
84865544952
-
Mitochondrial fission, fusion, and stress
-
Youle RJ, van der Bliek AM. Mitochondrial fission, fusion, and stress. Science. 2012;337:1062-5.
-
(2012)
Science
, vol.337
, pp. 1062-1065
-
-
Youle, R.J.1
Bliek, A.M.2
-
106
-
-
77952236126
-
Inhibiting mitochondrial fission protects the heart against ischemia/reperfusion injury
-
Ong S-B, Subrayan S, Lim SY, Yellon DM, Davidson SM, Hausenloy DJ. Inhibiting mitochondrial fission protects the heart against ischemia/reperfusion injury. Circulation. 2010;121:2012-22.
-
(2010)
Circulation
, vol.121
, pp. 2012-2022
-
-
Ong, S.-B.1
Subrayan, S.2
Lim, S.Y.3
Yellon, D.M.4
Davidson, S.M.5
Hausenloy, D.J.6
-
107
-
-
84925464684
-
Inhibition of the mitochondrial fission protein dynamin-related protein 1 improves survival in a murine cardiac arrest model
-
Sharp WW, Beiser DG, Fang YH, Han M, Piao L, Varughese J, et al. Inhibition of the mitochondrial fission protein dynamin-related protein 1 improves survival in a murine cardiac arrest model. Crit Care Med. 2015;43:e38-47.
-
(2015)
Crit Care Med
, vol.43
-
-
Sharp, W.W.1
Beiser, D.G.2
Fang, Y.H.3
Han, M.4
Piao, L.5
Varughese, J.6
-
110
-
-
0037376574
-
Increased Na+/H+-exchange activity is the cause of increased [Na+]i and underlies disturbed calcium handling in the rabbit pressure and volume overload heart failure model
-
Baartscheer A, Schumacher CA, van Borren MMGJ, Belterman CNW, Coronel R, Fiolet JWT. Increased Na+/H+-exchange activity is the cause of increased [Na+]i and underlies disturbed calcium handling in the rabbit pressure and volume overload heart failure model. Cardiovasc Res. 2003;57:1015-24.
-
(2003)
Cardiovasc Res
, vol.57
, pp. 1015-1024
-
-
Baartscheer, A.1
Schumacher, C.A.2
Borren, M.M.G.J.3
Belterman, C.N.W.4
Coronel, R.5
Fiolet, J.W.T.6
-
111
-
-
0037377081
-
Intracellular Na in animal models of hypertrophy and heart failure: contractile function and arrhythmogenesis
-
Pogwizd SM, Sipido KR, Verdonck F, Bers DM. Intracellular Na in animal models of hypertrophy and heart failure: contractile function and arrhythmogenesis. Cardiovasc Res. 2003;57:887-96.
-
(2003)
Cardiovasc Res
, vol.57
, pp. 887-896
-
-
Pogwizd, S.M.1
Sipido, K.R.2
Verdonck, F.3
Bers, D.M.4
-
114
-
-
47249152693
-
+-exchanger causes regression of hypertrophy, heart failure, and ionic and electrophysiological remodelling
-
+-exchanger causes regression of hypertrophy, heart failure, and ionic and electrophysiological remodelling. Br J Pharmacol. 2008;154:1266-75.
-
(2008)
Br J Pharmacol
, vol.154
, pp. 1266-1275
-
-
Baartscheer, A.1
Hardziyenka, M.2
Schumacher, C.A.3
Belterman, C.N.W.4
Borren, M.M.G.J.5
Verkerk, A.O.6
-
116
-
-
84991712516
-
Empagliflozin decreases myocardial cytoplasmic Na(+) through inhibition of the cardiac Na(+)/H(+) exchanger in rats and rabbits
-
Baartscheer A, Schumacher CA, Wüst RCI, Fiolet JWT, Stienen GJM, Coronel R, et al. Empagliflozin decreases myocardial cytoplasmic Na(+) through inhibition of the cardiac Na(+)/H(+) exchanger in rats and rabbits. Diabetologia. 2017;60:568-73.
-
(2017)
Diabetologia
, vol.60
, pp. 568-573
-
-
Baartscheer, A.1
Schumacher, C.A.2
Wüst, R.C.I.3
Fiolet, J.W.T.4
Stienen, G.J.M.5
Coronel, R.6
-
117
-
-
53549099939
-
2+ uptake in myocytes from failing hearts restores energy supply and demand matching
-
2+ uptake in myocytes from failing hearts restores energy supply and demand matching. Circ Res. 2008;103:279-88.
-
(2008)
Circ Res
, vol.103
, pp. 279-288
-
-
Liu, T.1
O'Rourke, B.2
-
118
-
-
84870241098
-
Altered sarcoplasmic reticulum calcium cycling-targets for heart failure therapy
-
Kho C, Lee A, Hajjar RJ. Altered sarcoplasmic reticulum calcium cycling-targets for heart failure therapy. Nat Rev Cardiol. 2012;9:717-33.
-
(2012)
Nat Rev Cardiol.
, vol.9
, pp. 717-733
-
-
Kho, C.1
Lee, A.2
Hajjar, R.J.3
-
119
-
-
50649097202
-
The cardiac sarcoplasmic/endoplasmic reticulum calcium ATPase: a potent target for cardiovascular diseases
-
Kawase Y, Hajjar RJ. The cardiac sarcoplasmic/endoplasmic reticulum calcium ATPase: a potent target for cardiovascular diseases. Nat Clin Pract Cardiovasc Med. 2008;5:554-65.
-
(2008)
Nat Clin Pract Cardiovasc Med.
, vol.5
, pp. 554-565
-
-
Kawase, Y.1
Hajjar, R.J.2
-
120
-
-
85049854892
-
Upregulation of sodium-glucose cotransporter 2 (SGLT2) expression in cultured senescent endothelial cells and in arterial sites at risk in vivo in rats
-
Park SH, Khemais-Benkhiat S, Idris-Khodja N, Amoura L, Abbas M, Auger C, et al. Upregulation of sodium-glucose cotransporter 2 (SGLT2) expression in cultured senescent endothelial cells and in arterial sites at risk in vivo in rats. Arch Cardiovasc Dis Suppl. 2018;10:224.
-
(2018)
Arch Cardiovasc Dis Suppl.
, vol.10
, pp. 224
-
-
Park, S.H.1
Khemais-Benkhiat, S.2
Idris-Khodja, N.3
Amoura, L.4
Abbas, M.5
Auger, C.6
-
121
-
-
84946434020
-
SGLT inhibitors attenuate NO-dependent vascular relaxation in the pulmonary artery but not in the coronary artery
-
Han Y, Cho Y-E, Ayon R, Guo R, Youssef KD, Pan M, et al. SGLT inhibitors attenuate NO-dependent vascular relaxation in the pulmonary artery but not in the coronary artery. Am J Physiol Lung Cell Mol Physiol. 2015;309:L1027-36.
-
(2015)
Am J Physiol Lung Cell Mol Physiol
, vol.309
-
-
Han, Y.1
Cho, Y.-E.2
Ayon, R.3
Guo, R.4
Youssef, K.D.5
Pan, M.6
-
122
-
-
85009349867
-
The SGLT-2 inhibitor dapagliflozin has a therapeutic effect on atherosclerosis in diabetic ApoE-/- mice
-
Leng W, Ouyang X, Lei X, Wu M, Chen L, Wu Q, et al. The SGLT-2 inhibitor dapagliflozin has a therapeutic effect on atherosclerosis in diabetic ApoE-/- mice. Mediators Inflamm. 2016;2016:6305735.
-
(2016)
Mediators Inflamm
, vol.2016
-
-
Leng, W.1
Ouyang, X.2
Lei, X.3
Wu, M.4
Chen, L.5
Wu, Q.6
|