메뉴 건너뛰기




Volumn 38, Issue 5, 2011, Pages 533-538

Altered systemic ketone body metabolism in advanced heart failure

Author keywords

Energy metabolism; Exercise tolerance physiology; Heart diseases metabolism; Heart failure blood physiopathology; Heart physiopathology; Ketone bodies blood metabolism; Muscle; Skeletal blood

Indexed keywords

CREATININE; FATTY ACID; GLUCOSE; KETONE BODY; NITROGEN; UREA;

EID: 83455179322     PISSN: 07302347     EISSN: 15266702     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (69)

References (41)
  • 1
    • 0004364201 scopus 로고    scopus 로고
    • The metabolism of the heart
    • Bing RJ. The metabolism of the heart. Harvey Lect 1954-1955;50:27-70.
    • Harvey Lect 1954-1955 , vol.50 , pp. 27-70
    • Bing, R.J.1
  • 2
    • 0018862072 scopus 로고
    • Utilization of energy-providing substrates in the isolated working rat heart
    • Taegtmeyer H, Hems R, Krebs HA. Utilization of energy-providing substrates in the isolated working rat heart. Bio-chem J 1980;186(3):701-11.
    • (1980) Bio-chem J , vol.186 , Issue.3 , pp. 701-11
    • Taegtmeyer, H.1    Hems, R.2    Krebs, H.A.3
  • 4
    • 0025266282 scopus 로고
    • Myocardial metabolism in insulin-deficient diabetic humans without coronary artery disease
    • Avogaro A, Nosadini R, Doria A, Fioretto P, Velussi M, Vigorito C, et al. Myocardial metabolism in insulin-deficient diabetic humans without coronary artery disease. Am J Physiol 1990;258(4 Pt 1):E606-18.
    • (1990) Am J Physiol , vol.258 , Issue.1-4 PT.
    • Avogaro, A.1    Nosadini, R.2    Doria, A.3    Fioretto, P.4    Velussi, M.5    Vigorito, C.6
  • 5
    • 0037046203 scopus 로고    scopus 로고
    • Adaptation and mal-adaptation of the heart in diabetes: Part I: General concepts
    • Taegtmeyer H, McNulty P, Young ME. Adaptation and mal- adaptation of the heart in diabetes: Part I: general concepts. Circulation 2002;105(14):1727-33.
    • (2002) Circulation , vol.105 , Issue.14 , pp. 1727-33
    • Taegtmeyer, H.1    McNulty, P.2    Young, M.E.3
  • 6
    • 0037117651 scopus 로고    scopus 로고
    • Adaptation and mal-adaptation of the heart in diabetes: Part II: Potential mechanisms
    • Young ME, McNulty P, Taegtmeyer H. Adaptation and mal-adaptation of the heart in diabetes: Part II: potential mechanisms. Circulation 2002;105(15):1861-70.
    • (2002) Circulation , vol.105 , Issue.15 , pp. 1861-70
    • Young, M.E.1    McNulty, P.2    Taegtmeyer, H.3
  • 8
    • 3342967512 scopus 로고    scopus 로고
    • Is the failing heart energy starved? On using chemical energy to support cardiac function
    • Ingwall JS, Weiss RG. Is the failing heart energy starved? On using chemical energy to support cardiac function. Circ Res 2004;95(2):135-45.
    • (2004) Circ Res , vol.95 , Issue.2 , pp. 135-45
    • Ingwall, J.S.1    Weiss, R.G.2
  • 9
    • 36849040149 scopus 로고    scopus 로고
    • Impaired myocardial metabolic reserve and substrate selection flexibility during stress in patients with idiopathic dilated cardiomyopathy
    • Neglia D, De Caterina A, Marraccini P, Natali A, Ciardetti M, Vecoli C, et al. Impaired myocardial metabolic reserve and substrate selection flexibility during stress in patients with idiopathic dilated cardiomyopathy. Am J Physiol Heart Circ Physiol 2007;293(6):H3270-8.
    • (2007) Am J Physiol Heart Circ Physiol , vol.293 , Issue.6
    • Neglia, D.1    de Caterina, A.2    Marraccini, P.3    Natali, A.4    Ciardetti, M.5    Vecoli, C.6
  • 10
    • 34547590901 scopus 로고    scopus 로고
    • Metabolic mechanisms in heart failure
    • Ashrafian H, Frenneaux MP, Opie LH. Metabolic mechanisms in heart failure. Circulation 2007;116(4):434-48.
    • (2007) Circulation , vol.116 , Issue.4 , pp. 434-48
    • Ashrafian, H.1    Frenneaux, M.P.2    Opie, L.H.3
  • 11
    • 37849047917 scopus 로고    scopus 로고
    • Insulin-resistant cardiomyopathy clinical evidence, mechanisms, and treatment options
    • Witteles RM, Fowler MB. Insulin-resistant cardiomyopathy clinical evidence, mechanisms, and treatment options. J Am Coll Cardiol 2008;51(2):93-102.
    • (2008) J Am Coll Cardiol , vol.51 , Issue.2 , pp. 93-102
    • Witteles, R.M.1    Fowler, M.B.2
  • 12
    • 65449166074 scopus 로고    scopus 로고
    • Lost in translation: Modulation of the metabolic-functional relation in the diabetic human heart
    • Gropler RJ. Lost in translation: modulation of the metabolic-functional relation in the diabetic human heart. Circulation 2009;119(15):2020-2.
    • (2009) Circulation , vol.119 , Issue.15 , pp. 2020-2022
    • Gropler, R.J.1
  • 13
    • 33947239659 scopus 로고    scopus 로고
    • The failing heart-an engine out of fuel
    • Neubauer S. The failing heart-an engine out of fuel. N Engl J Med 2007;356(11):1140-51.
    • (2007) N Engl J Med , vol.356 , Issue.11 , pp. 1140-51
    • Neubauer, S.1
  • 14
    • 0021916108 scopus 로고
    • Evaluation of energy metabolism in skeletal muscle of patients with heart failure with gated phosphorus-31 nuclear magnetic resonance
    • Wilson JR, Fink L, Maris J, Ferraro N, Power-Vanwart J, Eleff S, Chance B. Evaluation of energy metabolism in skeletal muscle of patients with heart failure with gated phosphorus-31 nuclear magnetic resonance. Circulation 1985;71(1):57-62.
    • (1985) Circulation , vol.71 , Issue.1 , pp. 57-62
    • Wilson, J.R.1    Fink, L.2    Maris, J.3    Ferraro, N.4    Power-Vanwart, J.5    Eleff, S.6    Chance, B.7
  • 16
    • 0026554586 scopus 로고
    • Contribution of skeletal muscle atrophy to exercise intolerance and altered muscle metabolism in heart failure
    • Mancini DM, Walter G, Reichek N, Lenkinski R, McCully KK, Mullen JL, Wilson JR. Contribution of skeletal muscle atrophy to exercise intolerance and altered muscle metabolism in heart failure. Circulation 1992;85(4):1364-73.
    • (1992) Circulation , vol.85 , Issue.4 , pp. 1364-73
    • Mancini, D.M.1    Walter, G.2    Reichek, N.3    Lenkinski, R.4    McCully, K.K.5    Mullen, J.L.6    Wilson, J.R.7
  • 17
    • 77955496945 scopus 로고    scopus 로고
    • Making the case for skeletal myopathy as the major limitation of exercise capacity in heart failure
    • Middlekauff HR. Making the case for skeletal myopathy as the major limitation of exercise capacity in heart failure. Circ Heart Fail 2010;3(4):537-46.
    • (2010) Circ Heart Fail , vol.3 , Issue.4 , pp. 537-46
    • Middlekauff, H.R.1
  • 18
    • 1042299789 scopus 로고    scopus 로고
    • The therapeutic implications of ketone bodies: The effects of ketone bodies in pathological conditions: Ketosis, ketogenic diet, redox states, insulin resistance, and mitochondrial metabolism
    • Veech RL. The therapeutic implications of ketone bodies: the effects of ketone bodies in pathological conditions: ketosis, ketogenic diet, redox states, insulin resistance, and mitochondrial metabolism. Prostaglandins Leukot Essent Fatty Acids 2004;70(3):309-19.
    • (2004) Prostaglandins Leukot Essent Fatty Acids , vol.70 , Issue.3 , pp. 309-19
    • Veech, R.L.1
  • 19
    • 34250936135 scopus 로고
    • On the significance of acetoacetate and beta-hydroxybutyrate in human myocardial metabolism [in German]
    • Rudolph W, Maas D, Richter J, Hasinger F, Hofmann H, Dohrn P. On the significance of acetoacetate and beta-hydroxybutyrate in human myocardial metabolism [in German]. Klin Wochenschr 1965;43:445-51.
    • (1965) Klin Wochenschr , vol.43 , pp. 445-51
    • Rudolph, W.1    Maas, D.2    Richter, J.3    Hasinger, F.4    Hofmann, H.5    Dohrn, P.6
  • 20
    • 0018336297 scopus 로고
    • Mitochondrial function in the heart
    • Williamson JR. Mitochondrial function in the heart. Annu Rev Physiol 1979;41:485-506.
    • (1979) Annu Rev Physiol , vol.41 , pp. 485-506
    • Williamson, J.R.1
  • 21
    • 0018876377 scopus 로고
    • Physiological roles of ketone bodies as substrates and signals in mammalian tissues
    • Robinson AM, Williamson DH. Physiological roles of ketone bodies as substrates and signals in mammalian tissues. Physiol Rev 1980;60(1):143-87.
    • (1980) Physiol Rev , vol.60 , Issue.1 , pp. 143-87
    • Robinson, A.M.1    Williamson, D.H.2
  • 22
    • 0026065784 scopus 로고
    • Changes in citric acid cycle flux and anaplerosis antedate the functional decline in isolated rat hearts utilizing acetoacetate
    • Russell RR 3rd, Taegtmeyer H. Changes in citric acid cycle flux and anaplerosis antedate the functional decline in isolated rat hearts utilizing acetoacetate. J Clin Invest 1991;87(2):384-90.
    • (1991) J Clin Invest , vol.87 , Issue.2 , pp. 384-90
    • Russell III., R.R.1    Taegtmeyer, H.2
  • 23
    • 0026603044 scopus 로고
    • Effects of diabetes and insulin on ketone bodies metabolism in heart
    • Sultan AM. Effects of diabetes and insulin on ketone bodies metabolism in heart. Mol Cell Biochem 1992;110(1):17-23.
    • (1992) Mol Cell Biochem , vol.110 , Issue.1 , pp. 17-23
    • Sultan, A.M.1
  • 24
    • 0028793745 scopus 로고
    • Substrate selection in the isolated working rat heart: Effects of reperfusion, afterload, and concentration
    • Jeffrey FM, Diczku V, Sherry AD, Malloy CR. Substrate selection in the isolated working rat heart: effects of reperfusion, afterload, and concentration. Basic Res Cardiol 1995;90(5): 388-96.
    • (1995) Basic Res Cardiol , vol.90 , Issue.5 , pp. 388-96
    • Jeffrey, F.M.1    Diczku, V.2    Sherry, A.D.3    Malloy, C.R.4
  • 26
    • 0015694982 scopus 로고
    • Studies on myocardial blood f low, oxygen consumption, and myocardial metabolism in patients with cardiomyopathy
    • Rudolph W, Schinz A. Studies on myocardial blood f low, oxygen consumption, and myocardial metabolism in patients with cardiomyopathy. Recent Adv Stud Cardiac Struct Metab 1973;2:739-49.
    • (1973) Recent Adv Stud Cardiac Struct Metab , vol.2 , pp. 739-49
    • Rudolph, W.1    Schinz, A.2
  • 28
    • 1042276529 scopus 로고    scopus 로고
    • Pathways and control of ketone body metabolism: On the fringe of lipid biochemistry
    • Fukao T, Lopaschuk GD, Mitchell GA. Pathways and control of ketone body metabolism: on the fringe of lipid biochemistry. Prostaglandins Leukot Essent Fatty Acids 2004;70(3): 243-51.
    • (2004) Prostaglandins Leukot Essent Fatty Acids , vol.70 , Issue.3 , pp. 243-51
    • Fukao, T.1    Lopaschuk, G.D.2    Mitchell, G.A.3
  • 29
    • 79953196884 scopus 로고    scopus 로고
    • Obligate role for ketone body oxidation in neonatal metabolic homeostasis
    • Cotter DG, d'Avignon DA, Wentz AE, Weber ML, Crawford PA. Obligate role for ketone body oxidation in neonatal metabolic homeostasis. J Biol Chem 2011;286(9):6902-10.
    • (2011) J Biol Chem , vol.286 , Issue.9 , pp. 6902-10
    • Cotter, D.G.1    D'avignon, D.A.2    Wentz, A.E.3    Weber, M.L.4    Crawford, P.A.5
  • 30
    • 0015310967 scopus 로고
    • Succinyl-CoA: 3-ketoacid CoA transferase deficiency. A cause for ketoacidosis in infancy
    • Tildon JT, Cornblath M. Succinyl-CoA: 3-ketoacid CoA transferase deficiency. A cause for ketoacidosis in infancy. J Clin Invest 1972;51(3):493-8.
    • (1972) J Clin Invest , vol.51 , Issue.3 , pp. 493-498
    • Tildon, J.T.1    Cornblath, M.2
  • 31
    • 0034720862 scopus 로고    scopus 로고
    • Cardiac complications in pediatric patients on the ketogenic diet
    • Best TH, Franz DN, Gilbert DL, Nelson DP, Epstein MR. Cardiac complications in pediatric patients on the ketogenic diet. Neurology 2000;54(12):2328-30.
    • (2000) Neurology , vol.54 , Issue.12 , pp. 2328-30
    • Best, T.H.1    Franz, D.N.2    Gilbert, D.L.3    Nelson, D.P.4    Epstein, M.R.5
  • 32
    • 78649740255 scopus 로고    scopus 로고
    • Integrative research: The key to unlocking the mysteries of chronic heart failure and skeletal muscle dysfunction
    • Trinity JD, Richardson RS. Integrative research: the key to unlocking the mysteries of chronic heart failure and skeletal muscle dysfunction. Am J Physiol Heart Circ Physiol 2010; 299(6):H1750-2.
    • (2010) Am J Physiol Heart Circ Physiol , vol.299 , Issue.6
    • Trinity, J.D.1    Richardson, R.S.2
  • 33
    • 79957437777 scopus 로고    scopus 로고
    • Functional adiponectin resistance and exercise intolerance in heart failure
    • Van Berendoncks AM, Conraads VM. Functional adiponectin resistance and exercise intolerance in heart failure. Curr Heart Fail Rep 2011;8(2):113-22.
    • (2011) Curr Heart Fail Rep , vol.8 , Issue.2 , pp. 113-22
    • van Berendoncks, A.M.1    Conraads, V.M.2
  • 34
    • 57349122306 scopus 로고    scopus 로고
    • The role of amino acids in the modulation of cardiac metabolism during ischemia and heart failure
    • Marazzi G, Rosanio S, Caminiti G, Dioguardi FS, Mercuro G. The role of amino acids in the modulation of cardiac metabolism during ischemia and heart failure. Curr Pharm Des 2008;14(25):2592-604.
    • (2008) Curr Pharm Des , vol.14 , Issue.25 , pp. 2592-604
    • Marazzi, G.1    Rosanio, S.2    Caminiti, G.3    Dioguardi, F.S.4    Mercuro, G.5
  • 35
    • 79953755716 scopus 로고    scopus 로고
    • Catabolism of branched-chain amino acids in heart failure: Insights from genetic models
    • Sun H, Lu G, Ren S, Chen J, Wang Y. Catabolism of branched-chain amino acids in heart failure: insights from genetic models. Pediatr Cardiol 2011;32(3):305-10.
    • (2011) Pediatr Cardiol , vol.32 , Issue.3 , pp. 305-10
    • Sun, H.1    Lu, G.2    Ren, S.3    Chen, J.4    Wang, Y.5
  • 36
    • 82455175350 scopus 로고    scopus 로고
    • Young women partition fatty acids towards ketone body production rather than VLDL-TAG synthesis, com- pared with young men
    • Marinou K, Adiels M, Hodson L, Frayn KN, Karpe F, Fielding BA. Young women partition fatty acids towards ketone body production rather than VLDL-TAG synthesis, com- pared with young men. Br J Nutr 2011;105(6):857-65.
    • (2011) Br J Nutr , vol.105 , Issue.6 , pp. 857-65
    • Marinou, K.1    Adiels, M.2    Hodson, L.3    Frayn, K.N.4    Karpe, F.5    Fielding, B.A.6
  • 38
    • 20544440861 scopus 로고    scopus 로고
    • Aging muscle
    • Nair KS. Aging muscle. Am J Clin Nutr 2005;81(5):953-63.
    • (2005) Am J Clin Nutr , vol.81 , Issue.5 , pp. 953-63
    • Nair, K.S.1
  • 40
    • 27944467935 scopus 로고    scopus 로고
    • Insulin secretion and glucose utilization are impaired under general anesthesia with sevoflurane as well as isoflurane in a concentration-independent manner
    • Tanaka T, Nabatame H, Tanifuji Y. Insulin secretion and glucose utilization are impaired under general anesthesia with sevoflurane as well as isoflurane in a concentration-independent manner. J Anesth 2005;19(4):277-81.
    • (2005) J Anesth , vol.19 , Issue.4 , pp. 277-81
    • Tanaka, T.1    Nabatame, H.2    Tanifuji, Y.3
  • 41
    • 0033023817 scopus 로고    scopus 로고
    • Effects of sevoflurane and isoflurane anesthesia on arterial ketone body ratio and liver function
    • Nishiyama T, Yokoyama T, Hanaoka K. Effects of sevoflurane and isoflurane anesthesia on arterial ketone body ratio and liver function. Acta Anaesthesiol Scand 1999;43(3):347-51.
    • (1999) Acta Anaesthesiol Scand , vol.43 , Issue.3 , pp. 347-51
    • Nishiyama, T.1    Yokoyama, T.2    Hanaoka, K.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.