Liraglutide alleviates diabetic cardiomyopathy by blocking CHOP-triggered apoptosis via the inhibition of the IRE-α pathway

Molecular Medicine Reports

Volumn 9, Issue 4, 2014, Pages 1254-1258

  Ji, Yuqiang ^a   Zhao, Zhao ^a   Cai, Tianzhi ^b   Yang, Pengkang ^a   Cheng, Manli ^a  

^a First Hosp of Xi'an Jiaotong Univ   (China)

^b XI'AN MEDICAL UNIVERSITY   (China)

Author keywords

Apoptosis; Cardiac function; Diabetic cardiomyopathy; Endoplasmic reticulum stress; Liraglutide

Indexed keywords

ACTIVATING TRANSCRIPTION FACTOR 6; CASPASE 12; ENZYME; GROWTH ARREST AND DNA DAMAGE INDUCIBLE PROTEIN 153; INOSITOL REQUIRING ENZYME ALPHA; LIRAGLUTIDE; STRESS ACTIVATED PROTEIN KINASE; UNCLASSIFIED DRUG; X BOX BINDING PROTEIN 1;

ANIMAL EXPERIMENT; ANIMAL MODEL; APOPTOSIS; ARTICLE; CONTROLLED STUDY; DIABETIC CARDIOMYOPATHY; ENDOPLASMIC RETICULUM STRESS; ENZYME INHIBITION; HEART EJECTION FRACTION; HEART MUSCLE CELL; MALE; NONHUMAN; RAT; UNFOLDED PROTEIN RESPONSE;

ANIMALS; APOPTOSIS; BLOOD GLUCOSE; DIABETIC CARDIOMYOPATHIES; DISEASE MODELS, ANIMAL; ELECTROCARDIOGRAPHY; ENDOPLASMIC RETICULUM STRESS; ENDORIBONUCLEASES; FASTING; GLUCAGON-LIKE PEPTIDE 1; MALE; MICE; MULTIENZYME COMPLEXES; MYOCARDIUM; MYOCYTES, CARDIAC; PROTEIN-SERINE-THREONINE KINASES; RATS; RATS, WISTAR; SIGNAL TRANSDUCTION; TRANSCRIPTION FACTOR CHOP;

EID: 84896535965     PISSN: 17912997     EISSN: 17913004     Source Type: Journal    
DOI: 10.3892/mmr.2014.1956     Document Type: Article

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