N-Acetylcysteine and allopurinol up-regulated the Jak/STAT3 and PI3K/Akt pathways via adiponectin and attenuated myocardial postischemic injury in diabetes

Free Radical Biology and Medicine

Volumn 63, Issue , 2013, Pages 291-303

  Wang, Tingting ^a,b   Mao, Xiaowen ^a   Li, Haobo ^a   Qiao, Shigang ^a   Xu, Aimin ^c   Wang, Junwen ^c   Lei, Shaoqing ^a   Liu, Zipeng ^a   Ng, Kwok F J ^a,b   Wong, Gordon T ^a   Vanhoutte, Paul M ^c   Irwin, Michael G ^a   Xia, Zhengyuan ^a,c  

^a UNIVERSITY OF HONG KONG   (Hong Kong)

^b HUAZHONG UNIVERSITY OF SCIENCE AND TECHNOLOGY   (China)

^c UNIVERSITY OF HONG KONG   (Hong Kong)

Author keywords

Adiponectin; Antioxidants; Diabetes; Jak2 STAT3; Myocardial ischemia injury; PI3K Akt

Indexed keywords

ACETYLCYSTEINE; ADIPONECTIN; ALLOPURINOL; GLUCOSE; JANUS KINASE; N BENZYL 2 CYANO 3 (3,4 DIHYDROXYPHENYL)ACRYLAMIDE; NITRIC OXIDE; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE B; SMALL INTERFERING RNA; STAT3 PROTEIN; WORTMANNIN;

ANIMAL CELL; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ATTENUATION; CELL DEATH; CELL VIABILITY; CONTROLLED STUDY; DIABETES MELLITUS; DRUG ANTAGONISM; DRUG MECHANISM; DRUG POTENTIATION; FLOW RATE; HEART INFARCTION SIZE; HEART MUSCLE CELL; HEART MUSCLE INJURY; HEART MUSCLE ISCHEMIA; HYPOXIA; IN VIVO STUDY; NONHUMAN; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN PHOSPHORYLATION; RAT; REOXYGENATION; REPERFUSION INJURY; STREPTOZOCIN DIABETES; SURVIVAL; TREATMENT DURATION; UPREGULATION; WESTERN BLOTTING;

RATTUS;

EID: 84879473184     PISSN: 08915849     EISSN: 18734596     Source Type: Journal    
DOI: 10.1016/j.freeradbiomed.2013.05.043     Document Type: Article

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