Sodium glucose transporter 2 (SGLT2) inhibition with empagliflozin improves cardiac diastolic function in a female rodent model of diabetes

Cardiovascular Diabetology

Volumn 16, Issue 1, 2017, Pages

  Habibi, Javad ^a,b   Aroor, Annayya R ^a,b   Sowers, James R ^a,b,c   Jia, Guanghong ^a,b   Hayden, Melvin R ^a   Garro, Mona ^a,b   Barron, Brady ^a,b   Mayoux, Eric ^e   Rector, R Scott ^b,d   Whaley Connell, Adam ^a,b   DeMarco, Vincent G ^a,b  

^a University of Missouri   (United States)

^b VETERANS AFFAIRS MEDICAL CENTER   (United States)

^c UNIVERSITY OF MISSOURI   (United States)

^d UNIVERSITY OF MISSOURI   (United States)

^e BOEHRINGER INGELHEIM PHARMA GMBH AND CO KG   (Germany)

Author keywords

Diastolic function; Empagliflozin; SGLT2 inhibitor

Indexed keywords

EMPAGLIFLOZIN; EPITHELIAL SODIUM CHANNEL; HEMOGLOBIN A1C; SERUM AND GLUCOCORTICOID REGULATED KINASE 1; SODIUM GLUCOSE COTRANSPORTER 2; BENZHYDRYL DERIVATIVE; GLUCOSIDE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BLOOD PRESSURE; CARDIAC MUSCLE CELL; CONTROLLED STUDY; DIABETES MELLITUS; DIASTOLE; DIASTOLIC RELAXATION; DRUG TARGETING; ECHOCARDIOGRAPHY; FEMALE; FIBROSING ALVEOLITIS; GLUCOSE BLOOD LEVEL; GLYCEMIC INDEX; HEART FUNCTION; HEART LEFT VENTRICLE FILLING PRESSURE; HEART LEFT VENTRICLE HYPERTROPHY; HEART MUSCLE FIBROSIS; HEART MUSCLE RELAXATION; HEART SEPTUM; NON INSULIN DEPENDENT DIABETES MELLITUS; NONHUMAN; PROTEIN EXPRESSION; ANIMAL; ANTAGONISTS AND INHIBITORS; C57BL MOUSE; DIABETES MELLITUS, TYPE 2; DISEASE MODEL; DRUG EFFECTS; HEART LEFT VENTRICLE FUNCTION; MOUSE; PATHOPHYSIOLOGY; PHYSIOLOGY; TRANSGENIC MOUSE;

ANIMALS; BENZHYDRYL COMPOUNDS; BLOOD PRESSURE; DIABETES MELLITUS, TYPE 2; DIASTOLE; DISEASE MODELS, ANIMAL; FEMALE; GLUCOSIDES; GLYCEMIC INDEX; MICE; MICE, INBRED C57BL; MICE, TRANSGENIC; SODIUM-GLUCOSE TRANSPORTER 2; VENTRICULAR FUNCTION, LEFT;

EID: 85010216514     PISSN: None     EISSN: 14752840     Source Type: Journal    
DOI: 10.1186/s12933-016-0489-z     Document Type: Article

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