메뉴 건너뛰기




Volumn 13, Issue 7, 2018, Pages 1662-1685

Directed differentiation of human induced pluripotent stem cells into mature kidney podocytes and establishment of a Glomerulus Chip

Author keywords

[No Author keywords available]

Indexed keywords

IRON OXIDE; NANOMATERIAL; NANOPARTICLE; NANOZYME; PEROXIDASE; UNCLASSIFIED DRUG;

EID: 85049830424     PISSN: 17542189     EISSN: 17502799     Source Type: Journal    
DOI: 10.1038/s41596-018-0007-8     Document Type: Article
Times cited : (129)

References (76)
  • 1
    • 0032491416 scopus 로고    scopus 로고
    • Embryonic stem cell lines derived from human blastocysts
    • Thomson, J. et al. Embryonic stem cell lines derived from human blastocysts. Science 282, 1145-1147 (1998).
    • (1998) Science , vol.282 , pp. 1145-1147
    • Thomson, J.1
  • 2
    • 36248966518 scopus 로고    scopus 로고
    • Induction of pluripotent stem cells from adult human fibroblasts by defined factors
    • Takahashi, K. et al. Induction of pluripotent stem cells from adult human fibroblasts by defined factors. Cell 131, 861-872 (2007).
    • (2007) Cell , vol.131 , pp. 861-872
    • Takahashi, K.1
  • 3
    • 84921913471 scopus 로고    scopus 로고
    • Engineered in vitro disease models
    • Benam, K. H. et al. Engineered in vitro disease models. Annu. Rev. Pathol. 10, 195-262 (2015).
    • (2015) Annu. Rev. Pathol. , vol.10 , pp. 195-262
    • Benam, K.H.1
  • 4
    • 84892734390 scopus 로고    scopus 로고
    • Pluripotent stem cells in regenerative medicine: Challenges and recent progress
    • Tabar, V. & Studer, L. Pluripotent stem cells in regenerative medicine: challenges and recent progress. Nat. Rev. Genet. 15, 82-92 (2014).
    • (2014) Nat. Rev. Genet. , vol.15 , pp. 82-92
    • Tabar, V.1    Studer, L.2
  • 5
    • 85020519193 scopus 로고    scopus 로고
    • Mature induced-pluripotent-stem-cell-derived human podocytes reconstitute kidney glomerular-capillary-wall function on a chip
    • Musah, S. et al. Mature induced-pluripotent-stem-cell-derived human podocytes reconstitute kidney glomerular-capillary-wall function on a chip. Nat. Biomed. Eng. 1, 0069 (2017).
    • (2017) Nat. Biomed. Eng. , vol.1 , pp. 0069
    • Musah, S.1
  • 7
    • 0029064234 scopus 로고
    • Cytoskeletal filament assembly and the control of cell spreading and function by extracellular matrix
    • Mooney, D. J., Langer, R. & Ingber, D. E. Cytoskeletal filament assembly and the control of cell spreading and function by extracellular matrix. J. Cell Sci. 108, 2311-20 (1995).
    • (1995) J. Cell Sci. , vol.108 , pp. 2311-2320
    • Mooney, D.J.1    Langer, R.2    Ingber, D.E.3
  • 8
    • 37549069749 scopus 로고    scopus 로고
    • No place like home: Anatomy and function of the stem cell niche
    • Jones, L. & Wagers, A. No place like home: anatomy and function of the stem cell niche. Nat. Rev. Mol. Cell Biol. 9, 11-21 (2008).
    • (2008) Nat. Rev. Mol. Cell Biol. , vol.9 , pp. 11-21
    • Jones, L.1    Wagers, A.2
  • 9
    • 33646340966 scopus 로고    scopus 로고
    • Mechanical control of tissue morphogenesis during embryological development
    • Ingber, D. Mechanical control of tissue morphogenesis during embryological development. Int. J. Dev. Biol. 50, 255-266 (2006).
    • (2006) Int. J. Dev. Biol. , vol.50 , pp. 255-266
    • Ingber, D.1
  • 10
    • 34250206996 scopus 로고    scopus 로고
    • A ROCK inhibitor permits survival of dissociated human embryonic stem cells
    • Watanabe, K. et al. A ROCK inhibitor permits survival of dissociated human embryonic stem cells. Nat. Biotechnol. 25, 681-686 (2007).
    • (2007) Nat. Biotechnol. , vol.25 , pp. 681-686
    • Watanabe, K.1
  • 11
    • 84864243791 scopus 로고    scopus 로고
    • Differentiation of human embryonic stem cells and induced pluripotent stem cells to cardiomyocytes: A methods overview
    • Mummery, C. et al. Differentiation of human embryonic stem cells and induced pluripotent stem cells to cardiomyocytes: a methods overview. Circ. Res. 111, 344-358 (2012).
    • (2012) Circ. Res. , vol.111 , pp. 344-358
    • Mummery, C.1
  • 12
    • 75749118484 scopus 로고    scopus 로고
    • High-throughput discovery of synthetic surfaces that support proliferation of pluripotent cells
    • Derda, R. et al. High-throughput discovery of synthetic surfaces that support proliferation of pluripotent cells. J. Am. Chem. Soc. 132, 1289-1295 (2010).
    • (2010) J. Am. Chem. Soc. , vol.132 , pp. 1289-1295
    • Derda, R.1
  • 13
    • 84870401897 scopus 로고    scopus 로고
    • Glycosaminoglycan-binding hydrogels enable mechanical control of human pluripotent stem cell self-renewal
    • Musah, S. et al. Glycosaminoglycan-binding hydrogels enable mechanical control of human pluripotent stem cell self-renewal. ACS Nano 6, 10168-10177 (2012).
    • (2012) ACS Nano , vol.6 , pp. 10168-10177
    • Musah, S.1
  • 14
    • 84907222899 scopus 로고    scopus 로고
    • Substratum-induced differentiation of human pluripotent stem cells reveals the coactivator YAP is a potent regulator of neuronal specification
    • Musah, S. et al. Substratum-induced differentiation of human pluripotent stem cells reveals the coactivator YAP is a potent regulator of neuronal specification. Proc. Natl Acad. Sci. USA 111, 13805-13810 (2014).
    • (2014) Proc. Natl Acad. Sci. USA , vol.111 , pp. 13805-13810
    • Musah, S.1
  • 15
    • 79952580022 scopus 로고    scopus 로고
    • Role of mechanical factors in fate decisions of stem cells
    • Li, D. et al. Role of mechanical factors in fate decisions of stem cells. Regen. Med. 6, 229-240 (2011).
    • (2011) Regen. Med. , vol.6 , pp. 229-240
    • Li, D.1
  • 16
    • 37849026460 scopus 로고    scopus 로고
    • Integrin beta1-mediated matrix assembly and signaling are critical for the normal development and function of the kidney glomerulus
    • Kanasaki, K. et al. Integrin beta1-mediated matrix assembly and signaling are critical for the normal development and function of the kidney glomerulus. Dev. Biol. 313, 584-593 (2008).
    • (2008) Dev. Biol. , vol.313 , pp. 584-593
    • Kanasaki, K.1
  • 17
    • 41149083878 scopus 로고    scopus 로고
    • β1 integrin expression by podocytes is required to maintain glomerular structural integrity
    • Pozzi, A. et al. β1 integrin expression by podocytes is required to maintain glomerular structural integrity. Dev. Biol. 316, 288-301 (2008).
    • (2008) Dev. Biol. , vol.316 , pp. 288-301
    • Pozzi, A.1
  • 18
    • 77953274486 scopus 로고    scopus 로고
    • Long-term self-renewal of human pluripotent stem cells on human recombinant laminin-511
    • Rodin, S. et al. Long-term self-renewal of human pluripotent stem cells on human recombinant laminin-511. Nat. Biotechnol. 28, 611-615 (2010).
    • (2010) Nat. Biotechnol. , vol.28 , pp. 611-615
    • Rodin, S.1
  • 19
    • 84871785632 scopus 로고    scopus 로고
    • Laminin E8 fragments support efficient adhesion and expansion of dissociated human pluripotent stem cells
    • Miyazaki, T. et al. Laminin E8 fragments support efficient adhesion and expansion of dissociated human pluripotent stem cells. Nat. Commun. 3, 1236 (2012).
    • (2012) Nat. Commun. , vol.3 , pp. 1236
    • Miyazaki, T.1
  • 20
    • 84875386413 scopus 로고    scopus 로고
    • Monitoring and robust induction of nephrogenic intermediate mesoderm from human pluripotent stem cells
    • Mae, S.-I. et al. Monitoring and robust induction of nephrogenic intermediate mesoderm from human pluripotent stem cells. Nat. Commun. 4, 1367 (2013).
    • (2013) Nat. Commun. , vol.4 , pp. 1367
    • Mae, S.-I.1
  • 21
    • 84945283561 scopus 로고    scopus 로고
    • Kidney organoids from human iPS cells contain multiple lineages and model human nephrogenesis
    • Takasato, M. et al. Kidney organoids from human iPS cells contain multiple lineages and model human nephrogenesis. Nature 526, 564-568 (2015).
    • (2015) Nature , vol.526 , pp. 564-568
    • Takasato, M.1
  • 22
    • 84947241512 scopus 로고    scopus 로고
    • Nephron organoids derived from human pluripotent stem cells model kidney development and injury
    • Morizane, R. et al. Nephron organoids derived from human pluripotent stem cells model kidney development and injury. Nat. Biotechnol. 33, 1193-1200 (2015).
    • (2015) Nat. Biotechnol. , vol.33 , pp. 1193-1200
    • Morizane, R.1
  • 23
    • 0028875577 scopus 로고
    • Long-term treatment of rats with FGF-2 results in focal segmental glomerulosclerosis
    • Kriz, W., Hähnel, B., Rösener, S. & Elger, M. Long-term treatment of rats with FGF-2 results in focal segmental glomerulosclerosis. Kidney Int. 48, 1435-1450 (1995).
    • (1995) Kidney Int. , vol.48 , pp. 1435-1450
    • Kriz, W.1    Hähnel, B.2    Rösener, S.3    Elger, M.4
  • 24
    • 0027511359 scopus 로고
    • Visceral glomerular epithelial cells can proliferate in vivo and synthesize platelet-derived growth factor B-chain
    • Floege, J. et al. Visceral glomerular epithelial cells can proliferate in vivo and synthesize platelet-derived growth factor B-chain. Am. J. Pathol. 142, 637-650 (1993).
    • (1993) Am. J. Pathol. , vol.142 , pp. 637-650
    • Floege, J.1
  • 25
    • 0026704619 scopus 로고
    • Basic fibroblast growth factor promotes proliferation of rat glomerular visceral epithelial cells in vitro
    • Takeuchi, A. et al. Basic fibroblast growth factor promotes proliferation of rat glomerular visceral epithelial cells in vitro. Am. J. Pathol. 141, 107-116 (1992).
    • (1992) Am. J. Pathol. , vol.141 , pp. 107-116
    • Takeuchi, A.1
  • 26
    • 0037093502 scopus 로고    scopus 로고
    • Podocyte process effacement in vivo
    • Shirato, I. Podocyte process effacement in vivo. Microsc. Res. Techn. 57, 241-246 (2002).
    • (2002) Microsc. Res. Techn. , vol.57 , pp. 241-246
    • Shirato, I.1
  • 27
    • 84887012341 scopus 로고    scopus 로고
    • Microfabrication of human organs-on-chips
    • Huh, D. et al. Microfabrication of human organs-on-chips. Nat. Protoc. 8, 2135-2157 (2013).
    • (2013) Nat. Protoc. , vol.8 , pp. 2135-2157
    • Huh, D.1
  • 28
    • 77954038080 scopus 로고    scopus 로고
    • Reconstituting organ-level lung functions on a chip
    • Huh, D. et al. Reconstituting organ-level lung functions on a chip. Science 328, 1662-1668 (2010).
    • (2010) Science , vol.328 , pp. 1662-1668
    • Huh, D.1
  • 29
    • 84934441012 scopus 로고    scopus 로고
    • Novel in vivo techniques to visualize kidney anatomy and function
    • Peti-Peterdi, J., Kidokoro, K. & Riquier-Brison, A. Novel in vivo techniques to visualize kidney anatomy and function. Kidney Int. 88, 44-51 (2015).
    • (2015) Kidney Int. , vol.88 , pp. 44-51
    • Peti-Peterdi, J.1    Kidokoro, K.2    Riquier-Brison, A.3
  • 30
    • 84884299771 scopus 로고    scopus 로고
    • Direct transcriptional reprogramming of adult cells to embryonic nephron progenitors
    • Hendry, C. et al. Direct transcriptional reprogramming of adult cells to embryonic nephron progenitors. J. Am. Soc. Nephrol. 24, 1424-1434 (2013).
    • (2013) J. Am. Soc. Nephrol. , vol.24 , pp. 1424-1434
    • Hendry, C.1
  • 31
    • 84906088790 scopus 로고    scopus 로고
    • Rapid and efficient differentiation of human pluripotent stem cells into intermediate mesoderm that forms tubules expressing kidney proximal tubular markers
    • Lam, A. Q. et al. Rapid and efficient differentiation of human pluripotent stem cells into intermediate mesoderm that forms tubules expressing kidney proximal tubular markers. J. Am. Soc. Nephrol. 25, 1211-1225 (2014).
    • (2014) J. Am. Soc. Nephrol. , vol.25 , pp. 1211-1225
    • Lam, A.Q.1
  • 32
    • 85013581701 scopus 로고    scopus 로고
    • Generation of nephron progenitor cells and kidney organoids from human pluripotent stem cells
    • Morizane, R. & Bonventre, J. V. Generation of nephron progenitor cells and kidney organoids from human pluripotent stem cells. Nat. Protoc. 12, 195-207 (2017).
    • (2017) Nat. Protoc. , vol.12 , pp. 195-207
    • Morizane, R.1    Bonventre, J.V.2
  • 33
    • 84891298711 scopus 로고    scopus 로고
    • Directing human embryonic stem cell differentiation towards a renal lineage generates a self-organizing kidney
    • Takasato, M. et al. Directing human embryonic stem cell differentiation towards a renal lineage generates a self-organizing kidney. Nat. Cell Biol. 16, 118-126 (2014).
    • (2014) Nat. Cell Biol. , vol.16 , pp. 118-126
    • Takasato, M.1
  • 34
    • 84873025518 scopus 로고    scopus 로고
    • Podocyte biology and pathogenesis of kidney disease
    • Reiser, J. & Sever, S. Podocyte biology and pathogenesis of kidney disease. Annu. Rev. Med. 64, 357-366 (2013).
    • (2013) Annu. Rev. Med. , vol.64 , pp. 357-366
    • Reiser, J.1    Sever, S.2
  • 35
    • 84866040728 scopus 로고    scopus 로고
    • Educational paper
    • Büscher, A. & Weber, S. Educational paper: the podocytopathies. Eur. J. Pediatr. 171, 1151-1160 (2012).
    • (2012) Eur. J. Pediatr. , vol.171 , pp. 1151-1160
    • Büscher, A.1    Weber, S.2
  • 36
    • 80052371835 scopus 로고    scopus 로고
    • Genetics of kidney failure and the evolving story of APOL1
    • Friedman, D. & Pollak, M. Genetics of kidney failure and the evolving story of APOL1. J. Clin. Invest. 121, 3367-3374 (2011).
    • (2011) J. Clin. Invest. , vol.121 , pp. 3367-3374
    • Friedman, D.1    Pollak, M.2
  • 37
    • 84901236529 scopus 로고    scopus 로고
    • Rare inherited kidney diseases: Challenges, opportunities, and perspectives
    • Devuyst, O., Knoers, N. V., Remuzzi, G. & Schaefer, F. Rare inherited kidney diseases: challenges, opportunities, and perspectives. Lancet 383, 1844-1859 (2014).
    • (2014) Lancet , vol.383 , pp. 1844-1859
    • Devuyst, O.1    Knoers, N.V.2    Remuzzi, G.3    Schaefer, F.4
  • 38
    • 84960153040 scopus 로고    scopus 로고
    • Glomerular disease: Novel candidate genes implicated in FSGS
    • Edwards, J. K. Glomerular disease: novel candidate genes implicated in FSGS. Nat. Rev. Nephrol. 12, 256 (2016).
    • (2016) Nat. Rev. Nephrol. , vol.12 , pp. 256
    • Edwards, J.K.1
  • 39
    • 84873355257 scopus 로고    scopus 로고
    • Systematic reviews of animal models: Methodology versus epistemology
    • Greek, R. & Menache, A. Systematic reviews of animal models: methodology versus epistemology. Int. J. Med. Sci. 10, 206-221 (2013).
    • (2013) Int. J. Med. Sci. , vol.10 , pp. 206-221
    • Greek, R.1    Menache, A.2
  • 41
    • 84882590738 scopus 로고    scopus 로고
    • Human kidney proximal tubule-on-a-chip for drug transport and nephrotoxicity assessment
    • Jang, K.-J. et al. Human kidney proximal tubule-on-a-chip for drug transport and nephrotoxicity assessment. Integr. Biol. 5, 1119-1129 (2013).
    • (2013) Integr. Biol. , vol.5 , pp. 1119-1129
    • Jang, K.-J.1
  • 42
    • 84990862178 scopus 로고    scopus 로고
    • Kidney-on-a-chip technology for renal proximal tubule tissue reconstruction
    • Nieskens, T. & Wilmer, M. Kidney-on-a-chip technology for renal proximal tubule tissue reconstruction. Eur. J. Pharmacol. 790, 46-56 (2016).
    • (2016) Eur. J. Pharmacol. , vol.790 , pp. 46-56
    • Nieskens, T.1    Wilmer, M.2
  • 43
    • 84956654664 scopus 로고    scopus 로고
    • Small airway-on-a-chip enables analysis of human lung inflammation and drug responses in vitro
    • Benam, K. H. et al. Small airway-on-a-chip enables analysis of human lung inflammation and drug responses in vitro. Nat. Methods 13, 151-157 (2016).
    • (2016) Nat. Methods , vol.13 , pp. 151-157
    • Benam, K.H.1
  • 44
    • 84930959624 scopus 로고    scopus 로고
    • A four-organ-chip for interconnected long-term co-culture of human intestine, liver, skin and kidney equivalents
    • Maschmeyer, I. et al. A four-organ-chip for interconnected long-term co-culture of human intestine, liver, skin and kidney equivalents. Lab Chip 15, 2688-2699 (2015).
    • (2015) Lab Chip , vol.15 , pp. 2688-2699
    • Maschmeyer, I.1
  • 45
    • 84990213264 scopus 로고    scopus 로고
    • Liver and kidney on chips: Microphysiological models to understand transporter function
    • Chang, S. Y., Weber, E. J., Ness, K. V., Eaton, D. L. & Kelly, E. J. Liver and kidney on chips: microphysiological models to understand transporter function. Clin. Pharmacol. Ther. 100, 464-478 (2016).
    • (2016) Clin. Pharmacol. Ther. , vol.100 , pp. 464-478
    • Chang, S.Y.1    Weber, E.J.2    Ness, K.V.3    Eaton, D.L.4    Kelly, E.J.5
  • 46
    • 84941254163 scopus 로고    scopus 로고
    • The multi-organ chip-a microfluidic platform for long-term multi-tissue coculture
    • Materne, E.-M. et al. The multi-organ chip-a microfluidic platform for long-term multi-tissue coculture. J. Vis. Exp. (98), e52526 (2015).
    • (2015) J. Vis. Exp. (98) , pp. e52526
    • Materne, E.-M.1
  • 47
    • 84953273098 scopus 로고    scopus 로고
    • Contributions of microbiome and mechanical deformation to intestinal bacterial overgrowth and inflammation in a human gut-on-a-chip
    • Kim, H., Li, H., Collins, J. & Ingber, D. Contributions of microbiome and mechanical deformation to intestinal bacterial overgrowth and inflammation in a human gut-on-a-chip. Proc. Natl Acad. Sci. USA 113, E7-15 (2016).
    • (2016) Proc. Natl Acad. Sci. USA , vol.113 , pp. E7-15
    • Kim, H.1    Li, H.2    Collins, J.3    Ingber, D.4
  • 48
    • 84901823942 scopus 로고    scopus 로고
    • Bone marrow-on-a-chip replicates hematopoietic niche physiology in vitro
    • Torisawa, Y. et al. Bone marrow-on-a-chip replicates hematopoietic niche physiology in vitro. Nat. Methods 11, 663-669 (2014).
    • (2014) Nat. Methods , vol.11 , pp. 663-669
    • Torisawa, Y.1
  • 49
    • 84960153682 scopus 로고    scopus 로고
    • Reverse engineering human pathophysiology with organs-on-chips
    • Ingber, D. Reverse engineering human pathophysiology with organs-on-chips. Cell 164, 1105-1109 (2016).
    • (2016) Cell , vol.164 , pp. 1105-1109
    • Ingber, D.1
  • 50
    • 84905754409 scopus 로고    scopus 로고
    • Microfluidic organs-on-chips
    • Bhatia, S. & Ingber, D. Microfluidic organs-on-chips. Nat. Biotechnol. 32, 760-772 (2014).
    • (2014) Nat. Biotechnol. , vol.32 , pp. 760-772
    • Bhatia, S.1    Ingber, D.2
  • 51
    • 85034812883 scopus 로고    scopus 로고
    • Physiologically-based pharmacokinetic and pharmacodynamic analysis enabled by microfluidically linked organs-on-chips
    • Prantil-Baun, R. et al. Physiologically-based pharmacokinetic and pharmacodynamic analysis enabled by microfluidically linked organs-on-chips. Annu. Rev. Pharmacol. Toxicol. 58, 37-64 (2018).
    • (2018) Annu. Rev. Pharmacol. Toxicol.
    • Prantil-Baun, R.1
  • 52
    • 85049848670 scopus 로고    scopus 로고
    • Bio-engineered human kidney for the study of nephrotoxicity and kidney disease
    • Des Rochers, T. M. et al. Bio-engineered human kidney for the study of nephrotoxicity and kidney disease. J. Tissue Eng. Regen. Med. 6, 1-429 (2012).
    • (2012) J. Tissue Eng. Regen. Med. , vol.6 , pp. 1-429
    • Des Rochers, T.M.1
  • 53
    • 84866355664 scopus 로고    scopus 로고
    • Rapid casting of patterned vascular networks for perfusable engineered three-dimensional tissues
    • Miller, J. et al. Rapid casting of patterned vascular networks for perfusable engineered three-dimensional tissues. Nat. Mater. 11, 768-774 (2012).
    • (2012) Nat. Mater. , vol.11 , pp. 768-774
    • Miller, J.1
  • 54
    • 84900988712 scopus 로고    scopus 로고
    • 3D bioprinting of vascularized, heterogeneous cell-laden tissue constructs
    • Kolesky, D. et al. 3D bioprinting of vascularized, heterogeneous cell-laden tissue constructs. Adv. Mater. 26, 3124-3130 (2014).
    • (2014) Adv. Mater. , vol.26 , pp. 3124-3130
    • Kolesky, D.1
  • 55
    • 84930857660 scopus 로고    scopus 로고
    • Cell-based therapy for kidney disease
    • Chung, H., Ko, I., Atala, A. & Yoo, J. Cell-based therapy for kidney disease. Korean J. Urol. 56, 412-421 (2015).
    • (2015) Korean J. Urol. , vol.56 , pp. 412-421
    • Chung, H.1    Ko, I.2    Atala, A.3    Yoo, J.4
  • 56
    • 84864439398 scopus 로고    scopus 로고
    • Podocyte culture: Tricks of the trade
    • Ni, L., Saleem, M. & Mathieson, P. Podocyte culture: tricks of the trade. Nephrology 17, 525-531 (2012).
    • (2012) Nephrology , vol.17 , pp. 525-531
    • Ni, L.1    Saleem, M.2    Mathieson, P.3
  • 57
    • 84939641932 scopus 로고    scopus 로고
    • One hundred ways to kill a podocyte
    • Saleem, M. A. One hundred ways to kill a podocyte. Nephrol. Dial. Transplant. 30, 1266-1271 (2015).
    • (2015) Nephrol. Dial. Transplant. , vol.30 , pp. 1266-1271
    • Saleem, M.A.1
  • 59
    • 84867027380 scopus 로고    scopus 로고
    • The directed differentiation of human iPS cells into kidney podocytes
    • Song, B. et al. The directed differentiation of human iPS cells into kidney podocytes. PLoS ONE 7, e46453 (2012).
    • (2012) PLoS ONE , vol.7 , pp. e46453
    • Song, B.1
  • 60
    • 84973450025 scopus 로고    scopus 로고
    • Generation of functional podocytes from human induced pluripotent stem cells
    • Ciampi, O. et al. Generation of functional podocytes from human induced pluripotent stem cells. Stem Cell Res. 17, 130-139 (2016).
    • (2016) Stem Cell Res. , vol.17 , pp. 130-139
    • Ciampi, O.1
  • 61
    • 79551677421 scopus 로고    scopus 로고
    • Reference maps of human ES and iPS cell variation enable high-throughput characterization of pluripotent cell lines
    • Bock, C. et al. Reference maps of human ES and iPS cell variation enable high-throughput characterization of pluripotent cell lines. Cell 144, 439-452 (2011).
    • (2011) Cell , vol.144 , pp. 439-452
    • Bock, C.1
  • 62
    • 85010870303 scopus 로고    scopus 로고
    • Modeling ALS with motor neurons derived from human induced pluripotent stem cells
    • Sances, S. et al. Modeling ALS with motor neurons derived from human induced pluripotent stem cells. Nat. Neurosci. 19, 542-553 (2016).
    • (2016) Nat. Neurosci. , vol.19 , pp. 542-553
    • Sances, S.1
  • 63
    • 33947545733 scopus 로고    scopus 로고
    • Functional neural development from human embryonic stem cells: Accelerated synaptic activity via astrocyte coculture
    • Johnson, A., Weick, J., Pearce, R. & Zhang, S.-C. Functional neural development from human embryonic stem cells: accelerated synaptic activity via astrocyte coculture. J. Neurosci. 27, 3069-3077 (2007).
    • (2007) J. Neurosci. , vol.27 , pp. 3069-3077
    • Johnson, A.1    Weick, J.2    Pearce, R.3    Zhang, S.-C.4
  • 64
    • 84925235094 scopus 로고    scopus 로고
    • Rapid neurogenesis through transcriptional activation in human stem cells
    • Busskamp, V. et al. Rapid neurogenesis through transcriptional activation in human stem cells. Mol. Syst. Biol. 10, 760 (2014).
    • (2014) Mol. Syst. Biol. , vol.10 , pp. 760
    • Busskamp, V.1
  • 65
    • 84926521955 scopus 로고    scopus 로고
    • Highly efficient Cas9-mediated transcriptional programming
    • Chavez, A. et al. Highly efficient Cas9-mediated transcriptional programming. Nat. Methods 12, 326-328 (2015).
    • (2015) Nat. Methods , vol.12 , pp. 326-328
    • Chavez, A.1
  • 66
    • 84901242248 scopus 로고    scopus 로고
    • Materials as stem cell regulators
    • Murphy, W., McDevitt, T. & Engler, A. Materials as stem cell regulators. Nat. Mater. 13, 547-557 (2014).
    • (2014) Nat. Mater. , vol.13 , pp. 547-557
    • Murphy, W.1    McDevitt, T.2    Engler, A.3
  • 67
    • 77951228475 scopus 로고    scopus 로고
    • Mechanical control of tissue and organ development
    • Mammoto, T. & Ingber, D. Mechanical control of tissue and organ development. Development 137, 1407-1420 (2010).
    • (2010) Development , vol.137 , pp. 1407-1420
    • Mammoto, T.1    Ingber, D.2
  • 68
    • 84881060292 scopus 로고    scopus 로고
    • Simple replica micromolding of biocompatible styrenic elastomers
    • Borysiak, M. et al. Simple replica micromolding of biocompatible styrenic elastomers. Lab Chip 13, 2773-2784 (2013).
    • (2013) Lab Chip , vol.13 , pp. 2773-2784
    • Borysiak, M.1
  • 69
    • 84883305025 scopus 로고    scopus 로고
    • Clear castable polyurethane elastomer for fabrication of microfluidic devices
    • Domansky, K. et al. Clear castable polyurethane elastomer for fabrication of microfluidic devices. Lab Chip 13, 3956-3964 (2013).
    • (2013) Lab Chip , vol.13 , pp. 3956-3964
    • Domansky, K.1
  • 70
    • 28844508345 scopus 로고    scopus 로고
    • Glomerular basement membrane thickness in normal adults and its application to the diagnosis of thin basement membrane disease: An Indian study
    • Rayat, C. S., Joshi, K., Sakhuja, V. & Datta, U. Glomerular basement membrane thickness in normal adults and its application to the diagnosis of thin basement membrane disease: an Indian study. Indian J. Pathol. Microbiol. 48, 453-458 (2005).
    • (2005) Indian J. Pathol. Microbiol. , vol.48 , pp. 453-458
    • Rayat, C.S.1    Joshi, K.2    Sakhuja, V.3    Datta, U.4
  • 71
    • 72049098211 scopus 로고    scopus 로고
    • Integration and application of vitrified collagen in multilayered microfluidic devices for corneal microtissue culture
    • Puleo, C., Ambrose, W., Takezawa, T., Elisseeff, J. & Wang, T.-H. Integration and application of vitrified collagen in multilayered microfluidic devices for corneal microtissue culture. Lab Chip 9, 3221-3227 (2009).
    • (2009) Lab Chip , vol.9 , pp. 3221-3227
    • Puleo, C.1    Ambrose, W.2    Takezawa, T.3    Elisseeff, J.4    Wang, T.-H.5
  • 72
    • 84862520770 scopus 로고    scopus 로고
    • Fiji: An open-source platform for biological-image analysis
    • Schindelin, J. et al. Fiji: an open-source platform for biological-image analysis. Nat. Methods 9, 676-682 (2012).
    • (2012) Nat. Methods , vol.9 , pp. 676-682
    • Schindelin, J.1
  • 73
    • 84863205849 scopus 로고    scopus 로고
    • NIH image to ImageJ: 25 years of image analysis
    • Schneider, C., Rasband, W. & Eliceiri, K. NIH image to ImageJ: 25 years of image analysis. Nat. Methods 9, 671-675 (2012).
    • (2012) Nat. Methods , vol.9 , pp. 671-675
    • Schneider, C.1    Rasband, W.2    Eliceiri, K.3
  • 74
    • 84865707513 scopus 로고    scopus 로고
    • Role of the podocyte (and glomerular endothelium) in building the GBM
    • Abrahamson, D. Role of the podocyte (and glomerular endothelium) in building the GBM. Semin. Nephrol. 32, 342-349 (2012).
    • (2012) Semin. Nephrol. , vol.32 , pp. 342-349
    • Abrahamson, D.1
  • 76
    • 79957565394 scopus 로고    scopus 로고
    • Organogenesis of the kidney glomerulus: Focus on the glomerular basement membrane
    • Miner, J. Organogenesis of the kidney glomerulus: focus on the glomerular basement membrane. Organogenesis 7, 75-82 (2011).
    • (2011) Organogenesis , vol.7 , pp. 75-82
    • Miner, J.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.