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Volumn 2015, Issue 98, 2015, Pages

The multi-organ chip - A microfluidic platform for long-term multi-tissue coculture

Author keywords

Bioengineering; Body on a chip; Human on a chip; In vitro substance testing; Issue 98; Liver; Microphysiological systems; Multi organ chip; Organoids; Organs on a chip; Skin; Tissue engineering; Toxicity test; Vasculature

Indexed keywords

BIOPSY; BIOREACTOR; CELL DIFFERENTIATION; COCULTURE; CYTOLOGY; DEVICES; ENDOTHELIUM CELL; HUMAN; LIVER; MICROFLUIDICS; PHYSIOLOGY; PROCEDURES; SKIN;

EID: 84941254163     PISSN: 1940087X     EISSN: None     Source Type: Journal    
DOI: 10.3791/52526     Document Type: Article
Times cited : (86)

References (25)
  • 1
    • 1642385430 scopus 로고    scopus 로고
    • Microscale tissue engineering using gravity-enforced cell assembly
    • Kelm, J. M., Fussenegger, M. Microscale tissue engineering using gravity-enforced cell assembly. Trends in biotechnology. 22, (4), 195-202 (2004).
    • (2004) Trends in Biotechnology , vol.22 , Issue.4 , pp. 195-202
    • Kelm, J.M.1    Fussenegger, M.2
  • 2
    • 84873579795 scopus 로고    scopus 로고
    • Human-on-a-chip Developments: A Translational Cutting-edge Alternative to Systemic Safety Assessment and Efficiency Evaluation of Substances in Laboratory Animals and Man
    • Marx, U., Walles, H., et al. Human-on-a-chip Developments: A Translational Cutting-edge Alternative to Systemic Safety Assessment and Efficiency Evaluation of Substances in Laboratory Animals and Man. ATLA. 40, (5), 235-257 (2012).
    • (2012) ATLA , vol.40 , Issue.5 , pp. 235-257
    • Marx, U.1    Walles, H.2
  • 4
    • 70349399012 scopus 로고    scopus 로고
    • Liver tissue engineering in the evaluation of drug safety
    • Dash, A., Inman, W., et al. Liver tissue engineering in the evaluation of drug safety. Expert opinion on drug metabolism & toxicology. 5, (10), 1159-1174 (2009).
    • (2009) Expert Opinion on Drug Metabolism & Toxicology , vol.5 , Issue.10 , pp. 1159-1174
    • Dash, A.1    Inman, W.2
  • 5
    • 84882260943 scopus 로고    scopus 로고
    • Chip-based liver equivalents for toxicity testing--organotypicalness versus cost-efficient high throughput
    • Materne, E. -M., Tonevitsky, A. G., Marx, U. Chip-based liver equivalents for toxicity testing--organotypicalness versus cost-efficient high throughput. Lab on a chip. 13, (18), 3481-3495 (2013).
    • (2013) Lab on a Chip , vol.13 , Issue.18 , pp. 3481-3495
    • Materne, E.-M.1    Tonevitsky, A.G.2    Marx, U.3
  • 6
    • 84862186471 scopus 로고    scopus 로고
    • Microengineered physiological biomimicry: Organs-on-chips
    • Huh, D., Torisawa, Y., Hamilton, G. A, Kim, H. J., Ingber, D. E. Microengineered physiological biomimicry: organs-on-chips. Lab on a chip. 12, (12), 2156-2164 (2012).
    • (2012) Lab on a Chip. , vol.12 , Issue.12 , pp. 2156-2164
    • Huh, D.1    Torisawa, Y.2    Hamilton, G.A.3    Kim, H.J.4    Ingber, D.E.5
  • 7
    • 1142293800 scopus 로고    scopus 로고
    • The design and fabrication of three-chamber microscale cell culture analog devices with integrated dissolved oxygen sensors
    • Sin, A., Chin, K. C., Jamil, M. F., Kostov, Y., Rao, G., Shuler, M. L. The design and fabrication of three-chamber microscale cell culture analog devices with integrated dissolved oxygen sensors. Biotechnology progress. 20, (1), 338-345 (2004).
    • (2004) Biotechnology Progress , vol.20 , Issue.1 , pp. 338-345
    • Sin, A.1    Chin, K.C.2    Jamil, M.F.3    Kostov, Y.4    Rao, G.5    Shuler, M.L.6
  • 8
    • 64749086511 scopus 로고    scopus 로고
    • A novel system for evaluation of drug mixtures for potential efficacy in treating multidrug resistant cancers
    • Tatosian, D. A, Shuler, M. L. A novel system for evaluation of drug mixtures for potential efficacy in treating multidrug resistant cancers. Biotechnology and bioengineering. 103, (1), 187-198 (2009).
    • (2009) Biotechnology and Bioengineering , vol.103 , Issue.1 , pp. 187-198
    • Tatosian, D.A.1    Shuler, M.L.2
  • 9
    • 84882253484 scopus 로고    scopus 로고
    • Integrating biological vasculature into a multi-organ-chip microsystem
    • Schimek, K., Busek, M., et al. Integrating biological vasculature into a multi-organ-chip microsystem. Lab on a chip. 13, (18), 3588-3598 (2013).
    • (2013) Lab on a Chip , vol.13 , Issue.18 , pp. 3588-3598
    • Schimek, K.1    Busek, M.2
  • 10
    • 84882252041 scopus 로고    scopus 로고
    • A dynamic multi-organ-chip for long-term cultivation and substance testing proven by 3D human liver and skin tissue co-culture
    • Wagner, I., Materne, E. -M., et al. A dynamic multi-organ-chip for long-term cultivation and substance testing proven by 3D human liver and skin tissue co-culture. Lab on a chip. 13, (18), 3538-3547 (2013).
    • (2013) Lab on a Chip , vol.13 , Issue.18 , pp. 3538-3547
    • Wagner, I.1    Materne, E.-M.2
  • 11
    • 78650773222 scopus 로고    scopus 로고
    • HepaRG human hepatic cell line utility as a surrogate for primary human hepatocytes in drug metabolism assessment in vitro
    • Vieira, U., et al. HepaRG human hepatic cell line utility as a surrogate for primary human hepatocytes in drug metabolism assessment in vitro. Journal of pharmacological and toxicological methods. 63, (1), 59-68 (2010).
    • (2010) Journal of Pharmacological and Toxicological Methods , vol.63 , Issue.1 , pp. 59-68
    • Vieira, U.1
  • 12
    • 17644370659 scopus 로고    scopus 로고
    • Three-dimensional co-culture of hepatocytes and stellate cells
    • Abu-Absi, S. F., Hansen, L. K., Hu, W. -S. Three-dimensional co-culture of hepatocytes and stellate cells. Cytotechnology. 45, (3), 125-140 (2004).
    • (2004) Cytotechnology , vol.45 , Issue.3 , pp. 125-140
    • Abu-Absi, S.F.1    Hansen, L.K.2    Hu, W.-S.3
  • 13
    • 84867753850 scopus 로고    scopus 로고
    • Three-dimensional HepaRG model as an attractive tool for toxicity testing
    • Leite, S. B., Wilk-Zasadna, I., et al. Three-dimensional HepaRG model as an attractive tool for toxicity testing. Toxicological sciences. 130, (1), 106-116 (2012).
    • (2012) Toxicological Sciences , vol.130 , Issue.1 , pp. 106-116
    • Leite, S.B.1    Wilk-Zasadna, I.2
  • 14
    • 8144228713 scopus 로고    scopus 로고
    • Tenascins. The international journal of biochemistry & cell biology
    • Chiquet-Ehrismann, R. Tenascins. The international journal of biochemistry & cell biology. 36, (6), 986-990 (2004).
    • (2004) 36, (6) , pp. 986-990
    • Chiquet-Ehrismann, R.1
  • 16
    • 84882288306 scopus 로고    scopus 로고
    • Skin and hair on-a-chip: In vitro skin models versus ex vivo tissue maintenance with dynamic perfusion
    • Ataç, B., Wagner, I., et al. Skin and hair on-a-chip: in vitro skin models versus ex vivo tissue maintenance with dynamic perfusion. Lab on a chip. 13, (18), 3555-3561 (2013).
    • (2013) Lab on a Chip , vol.13 , Issue.18 , pp. 3555-3561
    • Ataç, B.1    Wagner, I.2
  • 17
    • 77950438544 scopus 로고    scopus 로고
    • Microfluidic cell culture systems for drug research
    • Wu, M. -H., Huang, S., Lee, G. -B. Microfluidic cell culture systems for drug research. Lab on a chip. 10, (8), 939-956 (2010).
    • (2010) Lab on a Chip , vol.10 , Issue.8 , pp. 939-956
    • Wu, M.-H.1    Huang, S.2    Lee, G.-B.3
  • 18
    • 77953913798 scopus 로고    scopus 로고
    • Vascularised human tissue models A new approach for the refinement of biomedical research
    • Schanz, J., Pusch, J., Hansmann, J., Walles, H. Vascularised human tissue models A new approach for the refinement of biomedical research. Journal of Biotechnology. 148, (1), 56-63 (2010).
    • (2010) Journal of Biotechnology , vol.148 , Issue.1 , pp. 56-63
    • Schanz, J.1    Pusch, J.2    Hansmann, J.3    Walles, H.4
  • 19
    • 84920941811 scopus 로고    scopus 로고
    • Adipose-derived stem cells induce vascular tube formation of outgrowth endothelial cells in a fibrin matrix
    • Holnthoner, W., Hohenegger, K., et al. Adipose-derived stem cells induce vascular tube formation of outgrowth endothelial cells in a fibrin matrix. J Tissue Eng Regen Med. (2012).
    • (2012) J Tissue Eng Regen Med
    • Holnthoner, W.1    Hohenegger, K.2
  • 20
    • 0024502767 scopus 로고
    • Hepatocyte function and extracellular matrix geometry: Long-term culture in a sandwich configuration
    • Dunn, J. C. Y., Yarmush, M. L., Koebe, H. G., Tompkins, R. G. Hepatocyte function and extracellular matrix geometry: long-term culture in a sandwich configuration. FASEB Journal. 3, 174-177 (1989).
    • (1989) FASEB Journal , vol.3 , pp. 174-177
    • Dunn, J.1    Yarmush, M.L.2    Koebe, H.G.3    Tompkins, R.G.4
  • 21
    • 2942709867 scopus 로고    scopus 로고
    • (Polydimethylsiloxane) bioreactor for large-scale culture of hepatocytes
    • Leclerc, E., Sakai, Y., Fujii, T. Microfluidic PDMS (polydimethylsiloxane) bioreactor for large-scale culture of hepatocytes. Biotechnology progress. 20, (3), 750-755 (2004).
    • (2004) Biotechnology Progress , vol.20 , Issue.3 , pp. 750-755
    • Leclerc, E.1    Sakai, Y.2    Fujii, T.3    Microfluidic, P.4
  • 22
    • 33846032329 scopus 로고    scopus 로고
    • A microfluidic platform for 3-dimensional cell culture and cell-based assays
    • Kim, M. S., Yeon, J. H., Park, J. -K. A microfluidic platform for 3-dimensional cell culture and cell-based assays. Biomedical microdevices. 9, (1), 25-34 (2007).
    • (2007) Biomedical Microdevices , vol.9 , Issue.1 , pp. 25-34
    • Kim, M.S.1    Yeon, J.H.2    Park, J.-K.3
  • 23
    • 79953236870 scopus 로고    scopus 로고
    • Improvement of HepG2/C3A Cell Functions in a Microfluidic Biochip
    • Prot, J. -M., Aninat, C., et al. Improvement of HepG2/C3A Cell Functions in a Microfluidic Biochip. Biotechnology and bioengineering. 108, (7), 1704-1715 (2011).
    • (2011) Biotechnology and Bioengineering , vol.108 , Issue.7 , pp. 1704-1715
    • Prot, J.-M.1    Aninat, C.2
  • 24
    • 0038614704 scopus 로고    scopus 로고
    • Long-term culture of functional liver tissue: Three-dimensional coculture of primary hepatocytes and stellate cells
    • Riccalton-Banks, L., Liew, C., Bhandari, R., Fry, J., Shakesheff, K. Long-term culture of functional liver tissue: three-dimensional coculture of primary hepatocytes and stellate cells. Tissue engineering. 9, (3), 401-410 (2003).
    • (2003) Tissue Engineering , vol.9 , Issue.3 , pp. 401-410
    • Riccalton-Banks, L.1    Liew, C.2    Bhandari, R.3    Fry, J.4    Shakesheff, K.5
  • 25
    • 18444370256 scopus 로고    scopus 로고
    • A Microfabricated Array Bioreactor for Perfused 3D Liver Culture
    • Powers, M. J., Domansky, K., et al. A Microfabricated Array Bioreactor for Perfused 3D Liver Culture. Biotechnology and Bioengineering. 78, (3), 257-269 (2002).
    • (2002) Biotechnology and Bioengineering , vol.78 , Issue.3 , pp. 257-269
    • Powers, M.J.1    Domansky, K.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.