Nephron organoids derived from human pluripotent stem cells model kidney development and injury

Nature Biotechnology

Volumn 33, Issue 11, 2015, Pages 1193-1200

  Morizane, Ryuji ^a,b   Lam, Albert Q ^a,b,c   Freedman, Benjamin S ^a,b   Kishi, Seiji ^a,b   Valerius, M Todd ^a,b,c   Bonventre, Joseph V ^a,b,c  

^a BRIGHAM AND WOMEN S HOSPITAL   (United States)

^b HARVARD MEDICAL SCHOOL   (United States)

^c HARVARD STEM CELL INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CELLS; CYTOLOGY; DIAGNOSIS; TISSUE REGENERATION;

DEVELOPMENTAL POTENTIAL; DISEASE MODELING; ORGAN REGENERATION; ORGANOID CULTURES; PLURIPOTENT STEM CELLS; PROGENITOR CELL; PROXIMAL TUBULES; THREE-DIMENSIONAL CULTURE;

STEM CELLS;

NPC PROTEIN; PROTEIN; SALL1 PROTEIN; SIX2 PROTEIN; TRANSCRIPTION FACTOR PAX2; UNCLASSIFIED DRUG; WT1 PROTEIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL DIFFERENTIATION; CONTROLLED STUDY; CYTOPLASM; CYTOPLASM VESICLE; HENLE LOOP; HUMAN; HUMAN CELL; HUMAN TISSUE; IN VITRO STUDY; IN VIVO STUDY; KIDNEY DEVELOPMENT; KIDNEY DISTAL TUBULE; KIDNEY INJURY; KIDNEY PROXIMAL TUBULE; MOUSE; NEPHRON; NEPHROTOXICITY; NONHUMAN; PLURIPOTENT STEM CELL; PODOCYTE; PRIORITY JOURNAL; BIOLOGICAL MODEL; CELL CULTURE TECHNIQUE; CYTOLOGY; KIDNEY; MEDICAL RESEARCH; METABOLISM; PHYSIOLOGY; PROCEDURES; TISSUE CULTURE TECHNIQUE;

BIOMEDICAL RESEARCH; CELL CULTURE TECHNIQUES; CELL DIFFERENTIATION; HUMANS; KIDNEY; MODELS, BIOLOGICAL; NEPHRONS; ORGANOIDS; PLURIPOTENT STEM CELLS; TISSUE CULTURE TECHNIQUES;

EID: 84947241512     PISSN: 10870156     EISSN: 15461696     Source Type: Journal    
DOI: 10.1038/nbt.3392     Document Type: Article

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