The emergence of trophoblast cell-surface antigen 2 (TROP-2) as a novel cancer target

Oncotarget

Volumn 9, Issue 48, 2018, Pages 28989-29006

  Goldenberg, David M ^a,b   Stein, Rhona ^a   Sharkey, Robert M ^a,c  

^a CENTER FOR MOLECULAR MEDICINE AND IMMUNOLOGY   (United States)

^b IBC Pharmaceuticals Inc   (United States)

^c IMMUNOMEDICS INC   (United States)

Author keywords

Antibody drug conjugates; Immunotherapy; Sacituzumab govitecan; TACSTD2; TROP 2

Indexed keywords

AMPHIREGULIN; ANTINEOPLASTIC AGENT; CYCLIC AMP RESPONSIVE ELEMENT BINDING PROTEIN; CYCLIN D1; EPITHELIAL CELL ADHESION MOLECULE; GLYCOPROTEIN; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; MITOGEN ACTIVATED PROTEIN KINASE; PF 06664178; PROTEIN C JUN; RETINOBLASTOMA PROTEIN; SACITUZUMAB GOVITECAN; STAT1 PROTEIN; STAT3 PROTEIN; TROPHOBLAST CELL SURFACE ANTIGEN 2; TUMOR NECROSIS FACTOR; UNCLASSIFIED DRUG; UVOMORULIN; VIMENTIN;

ARTHRALGIA; BLADDER CANCER; BREAST CANCER; BULLOUS DERMATITIS; CARDIOMYOPATHY; CELL GROWTH; CELL INVASION; CELL MIGRATION; CELL PROLIFERATION; CHILL; CHRONIC OBSTRUCTIVE LUNG DISEASE; COLONY FORMATION; COLORECTAL CANCER; CONSTIPATION; CORNEA DYSTROPHY; DECREASED APPETITE; DIARRHEA; DRUG EFFICACY; DRUG SAFETY; DRUG TOLERABILITY; DYSPNEA; EPITHELIAL MESENCHYMAL TRANSITION; ESOPHAGUS CANCER; FATIGUE; GALLBLADDER CANCER; GELATINOUS DROP LIKE CORNEAL DYSTROPHY; GENE MUTATION; GENE OVEREXPRESSION; GLIOMA; HEAD AND NECK CANCER; HUMAN; INFUSION RELATED REACTION; KIDNEY CANCER; LIVER CELL CARCINOMA; LUNG CANCER; LUNG DISEASE; MOLECULARLY TARGETED THERAPY; MOUTH CANCER; MUCOSA INFLAMMATION; NAUSEA; NEUTROPENIA; NON SMALL CELL LUNG CANCER; NONHUMAN; OVARY CANCER; PANCREAS CANCER; PROSTATE CANCER; PROTEIN EXPRESSION; PROTEIN FUNCTION; PRURITUS; RADIOIMMUNOTHERAPY; RASH; REVIEW; SMALL CELL LUNG CANCER; STEM CELL; STOMACH CANCER; THYROID CANCER; TISSUE REGENERATION; TOXIC EPIDERMAL NECROLYSIS; TRANSITIONAL CELL CARCINOMA; TRIPLE NEGATIVE BREAST CANCER; TROP 2 GENE; UTERINE CERVIX CANCER; UTERUS CANCER;

EID: 85048931502     PISSN: None     EISSN: 19492553     Source Type: Journal    
DOI: 10.18632/oncotarget.25615     Document Type: Review

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