Cell-autonomous activation of the PI3-kinase pathway initiates endometrial cancer from adult uterine epithelium

Proceedings of the National Academy of Sciences of the United States of America

Volumn 107, Issue 40, 2010, Pages 17298-17303

  Memarzadeh, Sanaz ^a   Zong, Yang ^b   Janzen, Deanna M ^a   Goldstein, Andrew S ^b   Cheng, Donghui ^b   Kurita, Takeshi ^c   Schafenacker, Amanda M ^a   Huang, Jiaoti ^a   Witte, Owen N ^a,b  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c NORTHWESTERN UNIVERSITY   (United States)

Author keywords

Progesterone receptor; Tissue regeneration model; Uterine cancer

Indexed keywords

PHOSPHATIDYLINOSITOL 3 KINASE; PHOSPHATIDYLINOSITOL 3,4,5 TRISPHOSPHATE 3 PHOSPHATASE; PROTEIN KINASE B;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CANCER GENETICS; CONTROLLED STUDY; ENDOMETRIUM; ENDOMETRIUM CANCER; ENZYME ACTIVATION; FEMALE; IMMUNOHISTOCHEMISTRY; KNOCKOUT MOUSE; MOUSE; NONHUMAN; PRIORITY JOURNAL;

1-PHOSPHATIDYLINOSITOL 3-KINASE; ADENOCARCINOMA; ADULT; ANIMALS; ENDOMETRIAL NEOPLASMS; ENDOMETRIUM; ENZYME ACTIVATION; EPITHELIAL CELLS; FEMALE; HUMANS; MICE; MICE, INBRED STRAINS; PROTO-ONCOGENE PROTEINS C-AKT; PTEN PHOSPHOHYDROLASE; REGENERATION; SIGNAL TRANSDUCTION;

MURINAE;

EID: 78049315333     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1012548107     Document Type: Article

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