Tumor-associated calcium signal transducer 2 is required for the proper subcellular localization of claudin 1 and 7: Implications in the pathogenesis of gelatinous drop-like corneal dystrophy

American Journal of Pathology

Volumn 177, Issue 3, 2010, Pages 1344-1355

  Nakatsukasa, Mina ^a   Kawasaki, Satoshi ^a   Yamasaki, Kenta ^a   Fukuoka, Hideki ^a   Matsuda, Akira ^c   Tsujikawa, Motokazu ^b   Tanioka, Hidetoshi ^a   Nagata Takaoka, Maho ^a   Hamuro, Junji ^a   Kinoshita, Shigeru ^a  

^a KYOTO PREFECTURAL UNIVERSITY OF MEDICINE   (Japan)

^b OSAKA UNIVERSITY   (Japan)

^c JUNTENDO UNIVERSITY SCHOOL OF MEDICINE   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

ACTIN; CLAUDIN 1; CLAUDIN 4; CLAUDIN 7; GENE PRODUCT; OCCLUDIN; PROTEIN ZO1; TUMOR ASSOCIATED CALCIUM SIGNAL TRANSDUCER 2; UNCLASSIFIED DRUG;

ARTICLE; ASSAY; CELLULAR DISTRIBUTION; CONTROLLED STUDY; CORNEA DYSTROPHY; CORNEA EPITHELIUM; GELATINOUS DROP LIKE CORNEAL DYSTROPHY; GENE; GENE EXPRESSION; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOPRECIPITATION; PATHOGENESIS; PRIORITY JOURNAL; PROTEIN PROTEIN INTERACTION; PROXIMITY LIGATION ASSAY; RARE DISEASE; TACSTD2 GENE; TIGHT JUNCTION;

EID: 77956521624     PISSN: 00029440     EISSN: 15252191     Source Type: Journal    
DOI: 10.2353/ajpath.2010.100149     Document Type: Article

References (40)

1. Nakaizumi G: A rare case of corneal dystrophy. Acta Soc Ophthalmol Jpn 1914, 18:949-950
2. Fujiki K, Kanai A, Nakajima A: Gelatinous drop-like corneal dystrophy in Japanese population (abstract). 7th Int. Cong. Hum. Genet. 1986, 248-249
3. Kawano H, Fujiki K, Kanai A, Nakajima A: Prevalence of gelatinous drop-like corneal dystrophy in Japan. Atarashii Ganka 1992, 9:1879-1882
4. Weber FL, Babel J: Gelatinous drop-like dystrophy: a form of primary corneal amyloidosis. Arch Ophthalmol 1980, 98:144-148
5. Mondino BJ, Rabb MF, Sugar J, Sundar Raj CV, Brown SI: Primary familial amyloidosis of the cornea. Am J Ophthalmol 1981, 92: 732-736
6. Tsujikawa M, Kurahashi H, Tanaka T, Nishida K, Shimomura Y, Tano Y, Nakamura Y: Identification of the gene responsible for gelatinous drop-like corneal dystrophy. Nat Genet 1999, 21:420-423 (Pubitemid 29159581)
7. Tsujikawa M, Kurahashi H, Tanaka T, Okada M, Yamamoto S, Maeda N, Watanabe H, Inoue Y, Kiridoshi A, Matsumoto K, Ohashi Y, Kinoshita S, Shimomura Y, Nakamura Y, Tano Y: Homozygosity mapping of a gene responsible for gelatinous drop-like corneal dystrophy to chromosome 1p. Am J Hum Genet 1998, 63:1073-1077 (Pubitemid 30418577)
8. Kinoshita S, Nishida K, Dota A, Inatomi T, Koizumi N, Elliott A, Lewis D, Quantock A, Fullwood N: Epithelial barrier function and ultrastructure of gelatinous drop-like corneal dystrophy. Cornea 2000, 19: 551-555 (Pubitemid 30460898)
9. Quantock AJ, Nishida K, Kinoshita S: Histopathology of recurrent gelatinous drop-like corneal dystrophy. Cornea 1998, 17:215-221 (Pubitemid 28127921)
10. Takaoka M, Nakamura T, Ban Y, Kinoshita S: Phenotypic investigation of cell junction-related proteins in gelatinous drop-like corneal dystrophy. Invest Ophthalmol Vis Sci 2007, 48:1095-1101 (Pubitemid 351261402)
11. Klintworth GK, Sommer JR, Obrian G, Han L, Ahmed MN, Qumsiyeh MB, Lin PY, Basti S, Reddy MK, Kanai A, Hotta Y, Sugar J, Kumaramanickavel G, Munier F, Schorderet DF, El Matri L, Iwata F, Kaiser-Kupfer M, Nagata M, Nakayasu K, Hejtmancik JF, Teng CT: Familial subepithelial corneal amyloidosis (gelatinous drop-like corneal dystrophy): exclusion of linkage to lactoferrin gene. Mol Vis 1998, 4:31-38
12. Klintworth GK, Valnickova Z, Kielar RA, Baratz KH, Campbell RJ, Enghild JJ: Familial subepithelial corneal amyloidosis - a lactoferrin-related amyloidosis. Invest Ophthalmol Vis Sci 1997, 38:2756-2763 (Pubitemid 28009397)
13. Nishida K, Quantock AJ, Dota A, Choi-Miura NH, Kinoshita S: Apolipoproteins J and E co-localise with amyloid in gelatinous drop-like and lattice type I corneal dystrophies. Br J Ophthalmol 1999, 83:1178-1182 (Pubitemid 29469125)
14. Araki-Sasaki K, Ohashi Y, Sasabe T, Hayashi K, Watanabe H, Tano Y, Handa H: An SV40-immortalized human corneal epithelial cell line and its characterization. Invest Ophthalmol Vis Sci 1995, 36:614-621
15. Ebato B, Friend J, Thoft RA: Comparison of central and peripheral human corneal epithelium in tissue culture. Invest Ophthalmol Vis Sci 1987, 28:1450-1456 (Pubitemid 17147773)
16. Yamasaki K, Kawasaki S, Young RD, Fukuoka H, Tanioka H, Nakatsukasa M, Quantock AJ, Kinoshita S: Genomic aberrations and cellular heterogeneity in SV40-immortalized human corneal epithelial cells. Invest Ophthalmol Vis Sci 2009, 50:604-613
17. Szala S, Froehlich M, Scollon M, Kasai Y, Steplewski Z, Koprowski H, Linnenbach AJ: Molecular cloning of cDNA for the carcinoma-associated antigen GA733-2. Proc Natl Acad Sci USA. 1990, 87:3542-3546 (Pubitemid 20173673)
18. Strnad J, Hamilton AE, Beavers LS, Gamboa GC, Apelgren LD, Taber LD, Sportsman JR, Bumol TF, Sharp JD, Gadski RA: Molecular cloning and characterization of a human adenocarcinoma/epithelial cell surface antigen complementary DNA. Cancer Res 1989, 49:314-317 (Pubitemid 19049519)
19. Nubel T, Preobraschenski J, Tuncay H, Weiss T, Kuhn S, Ladwein M, Langbein L, Zoller M: Claudin-7 regulates EpCAM-mediated functions in tumor progression. Mol Cancer Res 2009, 7:285-299
20. Ladwein M, Pape UF, Schmidt DS, Schnolzer M, Fiedler S, Langbein L, Franke WW, Moldenhauer G, Zoller M: The cell-cell adhesion molecule EpCAM interacts directly with the tight junction protein claudin-7. Exp Cell Res 2005, 309:345-357 (Pubitemid 41317358)
21. Kuhn S, Koch M, Nubel T, Ladwein M, Antolovic D, Klingbeil P, Hildebrand D, Moldenhauer G, Langbein L, Franke WW, Weitz J, Zoller M: A complex of EpCAM, claudin-7. CD44 variant isoforms, and tetraspanins promotes colorectal cancer progression. Mol Cancer Res 2007, 5:553-567
22. Yoshida Y, Ban Y, Kinoshita S: Tight junction transmembrane protein claudin subtype expression and distribution in human corneal and conjunctival epithelium. Invest Ophthalmol Vis Sci 2009, 50:2103-2108
23. Ide T, Nishida K, Maeda N, Tsujikawa M, Yamamoto S, Watanabe H, Tano Y: A spectrum of clinical manifestations of gelatinous drop-like corneal dystrophy in Japan. Am J Ophthalmol 2004, 137:1081-1084
24. Fornaro M, Dell'Arciprete R, Stella M, Bucci C, Nutini M, Capri MG, Alberti S: Cloning of the gene encoding Trop-2, a cell-surface glycoprotein expressed by human carcinomas. Int J Cancer 1995, 62:610-618
25. Sears HF, Herlyn D, Steplewski Z, Koprowski H: Effects of monoclonal antibody immunotherapy on patients with gastrointestinal adenocarcinoma. J Biol Response Mod 1984, 3:138-150
26. Alberti S, Miotti S, Stella M, Klein CE, Fornaro M, Menard S, Colnaghi MI: Biochemical characterization of Trop-2, a cell surface molecule expressed by human carcinomas: formal proof that the monoclonal antibodies T16 and MOv-16 recognize Trop-2. Hybridoma 1992, 11:539-545
27. Lipinski M, Parks DR, Rouse RV, Herzenberg LA: Human trophoblast cell-surface antigens defined by monoclonal antibodies. Proc Natl Acad Sci USA. 1981, 78:5147-5150
28. Fradet Y, Cordon-Cardo C, Thomson T, Daly ME, Whitmore WF Jr, Lloyd KO, Melamed MR, Old LJ: Cell surface antigens of human bladder cancer defined by mouse monoclonal antibodies. Proc Natl Acad Sci USA 1984, 81:224-228
29. Miotti S, Canevari S, Menard S, Mezzanzanica D, Porro G, Pupa SM, Regazzoni M, Tagliabue E, Colnaghi MI: Characterization of human ovarian carcinoma-associated antigens defined by novel monoclonal antibodies with tumor-restricted specificity. Int J Cancer 1987, 39:297-303
30. Kiefer MC, Masiarz FR, Bauer DM, Zapf J: Identification and molecular cloning of two new 30-kDa insulin-like growth factor binding proteins isolated from adult human serum. J Biol Chem 1991, 266:9043-9049
31. Malthiery Y, Lissitzky S: Primary structure of human thyroglobulin deduced from the sequence of its 8448-base complementary DNA. Eur J Biochem 1987, 165:491-498
32. El Sewedy T, Fornaro M, Alberti S: Cloning of the murine TROP2 gene: conservation of a PIP2-binding sequence in the cytoplasmic domain of TROP-2. Int J Cancer 1998, 75:324-330
33. Ripani E, Sacchetti A, Corda D, Alberti S: Human Trop-2 is a tumor-associated calcium signal transducer. Int J Cancer 1998, 76:671-676
34. Morita K, Furuse M, Fujimoto K, Tsukita S: Claudin multigene family encoding four-transmembrane domain protein components of tight junction strands. Proc Natl Acad Sci USA. 1999, 96:511-516
35. Hamazaki Y, Itoh M, Sasaki H, Furuse M, Tsukita S: Multi-PDZ domain protein 1 (MUPP1) is concentrated at tight junctions through its possible interaction with claudin-1 and junctional adhesion molecule. J Biol Chem 2002, 277:455-461
36. Itoh M, Furuse M, Morita K, Kubota K, Saitou M, Tsukita S: Direct binding of three tight junction-associated MAGUKs. ZO-1, ZO-2, and ZO-3, with the COOH termini of claudins. J Cell Biol 1999, 147:1351-1363
37. Rahner C, Mitic LL, Anderson JM: Heterogeneity in expression and subcellular localization of claudins 2, 3, 4, and 5 in the rat liver, pancreas, and gut. Gastroenterology 2001, 120:411-422
38. Furuse M, Tsukita S: Claudins in occluding junctions of humans and flies. Trends Cell Biol 2006, 16:181-188
39. Furuse M, Sasaki H, Tsukita S: Manner of interaction of heterogeneous claudin species within and between tight junction strands. J Cell Biol 1999, 147:891-903
40. Kleiger G, Grothe R, Mallick P, Eisenberg D: GXXXG and AXXXA: common α-helical interaction motifs in proteins, particularly in extremophiles. Biochemistry 2002, 41:5990-5997