The Bitter Taste Receptor TAS2R16 Achieves High Specificity and Accommodates Diverse Glycoside Ligands by using a Two-faced Binding Pocket

Scientific Reports

Volumn 7, Issue 1, 2017, Pages

  Thomas, Anu ^a   Sulli, Chidananda ^a   Davidson, Edgar ^a   Berdougo, Eli ^a   Phillips, Morganne ^a   Puffer, Bridget A ^a   Paes, Cheryl ^a   Doranz, Benjamin J ^a   Rucker, Joseph B ^a  

^a Integral Molecular Inc   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

G PROTEIN COUPLED RECEPTOR; GLYCOSIDE; PROTEIN BINDING; TASTE RECEPTORS, TYPE 2;

BINDING SITE; CHEMISTRY; ENZYME SPECIFICITY; GENETICS; HEK293 CELL LINE; HUMAN; METABOLISM; MOLECULAR DOCKING;

BINDING SITES; GLYCOSIDES; HEK293 CELLS; HUMANS; MOLECULAR DOCKING SIMULATION; PROTEIN BINDING; RECEPTORS, G-PROTEIN-COUPLED; SUBSTRATE SPECIFICITY;

EID: 85048853110     PISSN: None     EISSN: 20452322     Source Type: Journal    
DOI: 10.1038/s41598-017-07256-y     Document Type: Article

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