Origin and differential selection of allelic variation at TAS2R16 associated with salicin bitter taste sensitivity in Africa

Molecular Biology and Evolution

Volumn 31, Issue 2, 2014, Pages 288-302

  Campbell, Michael C ^a   Ranciaro, Alessia ^a   Zinshteyn, Daniel ^a   Rawlings Goss, Renata ^a   Hirbo, Jibril ^a   Thompson, Simon ^a   Woldemeskel, Dawit ^a,b   Froment, Alain ^c   Rucker, Joseph B ^d   Omar, Sabah A ^e   Bodo, Jean Marie ^f   Nyambo, Thomas ^g   Belay, Gurja ^b   Drayna, Dennis ^h   Breslin, Paul A S ^i,j   Tishkoff, Sarah A ^a  

^a UNIVERSITY OF PENNSYLVANIA   (United States)

^b ADDIS ABABA UNIVERSITY   (Ethiopia)

^c MUSÉE DE L HOMME   (France)

^d Integral Molecular Inc   (United States)

^e KENYA MEDICAL RESEARCH INSTITUTE   (Kenya)

^f INSTITUTE OF AGRICULTURAL RESEARCH FOR DEVELOPMENT IRAD   (Cameroon)

^g MUHIMBILI UNIVERSITY OF HEALTH AND ALLIED SCIENCES   (Tanzania)

^h NATIONAL INSTITUTE ON DEAFNESS AND OTHER COMMUNICATION DISORDERS   (United States)

ⁱ MONELL CHEMICAL SENSES CENTER   (United States)

^j RUTGERS UNIVERSITY   (United States)

more..

Author keywords

African genetic diversity; genotype phenotype association; salicin taste perception; selection on standing variation

Indexed keywords

SALICIN;

AFRICA; ARTICLE; BITTER TASTE; CELL SURFACE; CLADISTICS; CONTROLLED STUDY; EXON; GENE; GENE EXPRESSION; GENE FREQUENCY; GENE MUTATION; GENETIC ASSOCIATION; GENETIC VARIABILITY; GENOTYPE PHENOTYPE CORRELATION; HAPLOTYPE; HOMOZYGOSITY; HUMAN; HUMAN EXPERIMENT; IN VITRO STUDY; NORMAL HUMAN; PHENOTYPE; PHENOTYPIC VARIATION; PHYLOGENY; POLYMORPHIC LOCUS; POPULATION DIFFERENTIATION; POPULATION GENETIC PARAMETERS; PURIFYING SELECTION; RECEPTOR GENE; SINGLE NUCLEOTIDE POLYMORPHISM; TAS2R16 GENE; TASTE ACUITY; TASTE BUD;

AFRICAN GENETIC DIVERSITY; GENOTYPE-PHENOTYPE ASSOCIATION; SALICIN TASTE PERCEPTION; SELECTION ON STANDING VARIATION;

AFRICAN CONTINENTAL ANCESTRY GROUP; ALLELES; BENZYL ALCOHOLS; EVOLUTION, MOLECULAR; EXONS; GENETIC ASSOCIATION STUDIES; GENETIC VARIATION; GLUCOSIDES; HAPLOTYPES; HUMANS; MALARIA; MODELS, GENETIC; PHYLOGENY; PHYLOGEOGRAPHY; POLYMORPHISM, SINGLE NUCLEOTIDE; RECEPTORS, G-PROTEIN-COUPLED; SELECTION, GENETIC; TASTE;

EID: 84893042536     PISSN: 07374038     EISSN: 15371719     Source Type: Journal    
DOI: 10.1093/molbev/mst211     Document Type: Article

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