Characterization of the β-D-Glucopyranoside binding site of the human bitter taste receptor hTAS2R16

Journal of Biological Chemistry

Volumn 285, Issue 36, 2010, Pages 28373-28378

  Sakurai, Takanobu ^a,b   Misaka, Takumi ^b   Ishiguro, Masaji ^c   Masuda, Katsuyoshi ^c   Sugawara, Taishi ^b   Ito, Keisuke ^b,e   Kobayashi, Takuya ^d   Matsuo, Shinji ^a   Ishimaru, Yoshiro ^b   Asakura, Tomiko ^b   Abe, Keiko ^b  

^a Shiga 525 0055   (Japan)

^b UNIVERSITY OF TOKYO   (Japan)

^c NIIGATA UNIVERSITY OF PHARMACY AND APPLIED LIFE SCIENCES   (Japan)

^d KYOTO UNIVERSITY FACULTY OF MEDICINE   (Japan)

^e UNIVERSITY OF SHIZUOKA   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACID RESIDUES; BINDING MODES; DOCKING SIMULATIONS; G PROTEIN COUPLED RECEPTORS; GLUCOPYRANOSIDE; LIGAND DOCKING; LIGAND RECOGNITION; MOLECULAR BASIS; RATIONAL DESIGN; STRUCTURAL INFORMATION; TASTE RECEPTORS; TRANSMEMBRANES;

AMINO ACIDS; BINDING ENERGY; BIOCHEMISTRY; DOCKING; LIGANDS; MAMMALS; ORGANIC ACIDS; PROTEINS;

BINDING SITES;

GLUCOPYRANOSIDE; SALICIN; BENZYL ALCOHOL DERIVATIVE; G PROTEIN COUPLED RECEPTOR; GLUCOSIDE; LIGAND; PROTEIN BINDING; TASTE RECEPTORS, TYPE 2;

ARTICLE; BINDING SITE; BITTER TASTE; COMPLEX FORMATION; CONTROLLED STUDY; HUMAN; HUMAN CELL; LIGAND BINDING; MOLECULAR DOCKING; MOLECULAR INTERACTION; MOLECULAR MODEL; MOLECULAR RECOGNITION; POINT MUTATION; PRIORITY JOURNAL; PROTEIN ANALYSIS; RECEPTOR BINDING; TASTE BUD; TASTE DISCRIMINATION; CELL LINE; CHEMICAL STRUCTURE; CHEMISTRY; ENZYME SPECIFICITY; GENETICS; METABOLISM; PROTEIN CONFORMATION; SITE DIRECTED MUTAGENESIS;

BENZYL ALCOHOLS; BINDING SITES; CELL LINE; GLUCOSIDES; HUMANS; LIGANDS; MODELS, MOLECULAR; MUTAGENESIS, SITE-DIRECTED; POINT MUTATION; PROTEIN BINDING; PROTEIN CONFORMATION; RECEPTORS, G-PROTEIN-COUPLED; SUBSTRATE SPECIFICITY;

MAMMALIA;

EID: 77956243395     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M110.144444     Document Type: Article

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