-
1
-
-
0036270698
-
Retro-translocation of proteins from the endoplasmic reticulum into the cytosol
-
B. Tsai Retro-translocation of proteins from the endoplasmic reticulum into the cytosol Nat. Rev. Mol. Cell Biol. 3 2002 246 255
-
(2002)
Nat. Rev. Mol. Cell Biol.
, vol.3
, pp. 246-255
-
-
Tsai, B.1
-
3
-
-
0042318739
-
Evolving questions and paradigm shifts in endoplasmic-reticulum- associated degradation (ERAD)
-
A.A. McCracken, and J.L. Brodsky Evolving questions and paradigm shifts in endoplasmic-reticulum-associated degradation (ERAD) BioEssays 25 2003 868 877
-
(2003)
BioEssays
, vol.25
, pp. 868-877
-
-
McCracken, A.A.1
Brodsky, J.L.2
-
4
-
-
0037566901
-
For whom the bell tolls: Protein quality control of the endoplasmic reticulum and the ubiquitin-proteasome connection
-
Z. Kostova, and D.H. Wolf For whom the bell tolls: protein quality control of the endoplasmic reticulum and the ubiquitin-proteasome connection EMBO J. 22 2003 2309 2317
-
(2003)
EMBO J.
, vol.22
, pp. 2309-2317
-
-
Kostova, Z.1
Wolf, D.H.2
-
5
-
-
0036843023
-
Secretory pathway quality control operating in Golgi, plasmalemmal, and endosomal systems
-
P. Arvan Secretory pathway quality control operating in Golgi, plasmalemmal, and endosomal systems Traffic 3 2002 771 780
-
(2002)
Traffic
, vol.3
, pp. 771-780
-
-
Arvan, P.1
-
6
-
-
0018987976
-
Intracellular protein topogenesis
-
G. Blobel Intracellular protein topogenesis Proc. Natl. Acad. Sci. U. S. A. 77 1980 1496 1500
-
(1980)
Proc. Natl. Acad. Sci. U. S. A.
, vol.77
, pp. 1496-1500
-
-
Blobel, G.1
-
7
-
-
0242488929
-
Translocons, thermodynamics, and the folding of membrane proteins
-
S.H. White Translocons, thermodynamics, and the folding of membrane proteins FEBS Lett. 555 2003 116 121
-
(2003)
FEBS Lett.
, vol.555
, pp. 116-121
-
-
White, S.H.1
-
8
-
-
0032987478
-
Membrane protein folding and stability: Physical principles
-
S.H. White, and W.C. Wimley Membrane protein folding and stability: physical principles Annu. Rev. Biophys. Biomol. Struct. 28 1999 319 365
-
(1999)
Annu. Rev. Biophys. Biomol. Struct.
, vol.28
, pp. 319-365
-
-
White, S.H.1
Wimley, W.C.2
-
9
-
-
0029112313
-
Forces and factors that contribute to the structural stability of membrane proteins
-
T. Haltia, and E. Freire Forces and factors that contribute to the structural stability of membrane proteins Biochim. Biophys. Acta 1241 1995 295 322
-
(1995)
Biochim. Biophys. Acta
, vol.1241
, pp. 295-322
-
-
Haltia, T.1
Freire, E.2
-
10
-
-
0033790343
-
Helical membrane protein folding, stability, and evolution
-
J.L. Popot, and D.M. Engelman Helical membrane protein folding, stability, and evolution Annu. Rev. Biochem. 69 2000 881 922
-
(2000)
Annu. Rev. Biochem.
, vol.69
, pp. 881-922
-
-
Popot, J.L.1
Engelman, D.M.2
-
11
-
-
0028086531
-
Specificity and promiscuity in membrane helix interactions
-
M.A. Lemmon, and D.M. Engelman Specificity and promiscuity in membrane helix interactions Q. Rev. Biophys. 27 1994 157 218
-
(1994)
Q. Rev. Biophys.
, vol.27
, pp. 157-218
-
-
Lemmon, M.A.1
Engelman, D.M.2
-
12
-
-
0033983453
-
Asparagine-mediated self-association of a model transmembrane helix
-
C. Choma Asparagine-mediated self-association of a model transmembrane helix Nat. Struct. Biol. 7 2000 161 166
-
(2000)
Nat. Struct. Biol.
, vol.7
, pp. 161-166
-
-
Choma, C.1
-
13
-
-
0034952420
-
Interhelical hydrogen bonds in the CFTR membrane domain
-
A.G. Therien Interhelical hydrogen bonds in the CFTR membrane domain Nat. Struct. Biol. 8 2001 597 601
-
(2001)
Nat. Struct. Biol.
, vol.8
, pp. 597-601
-
-
Therien, A.G.1
-
14
-
-
0007949690
-
Interhelical hydrogen bonding drives strong interactions in membrane proteins
-
F.X. Zhou Interhelical hydrogen bonding drives strong interactions in membrane proteins Nat. Struct. Biol. 7 2000 154 160
-
(2000)
Nat. Struct. Biol.
, vol.7
, pp. 154-160
-
-
Zhou, F.X.1
-
15
-
-
0035956884
-
Polar residues drive association of polyleucine transmembrane helices
-
F.X. Zhou Polar residues drive association of polyleucine transmembrane helices Proc. Natl. Acad. Sci. U. S. A. 98 2001 2250 2255
-
(2001)
Proc. Natl. Acad. Sci. U. S. A.
, vol.98
, pp. 2250-2255
-
-
Zhou, F.X.1
-
16
-
-
3042616595
-
A membrane protein required for dislocation of misfolded proteins from the ER
-
B.N. Lilley, and H.L. Ploegh A membrane protein required for dislocation of misfolded proteins from the ER Nature 429 2004 834 840
-
(2004)
Nature
, vol.429
, pp. 834-840
-
-
Lilley, B.N.1
Ploegh, H.L.2
-
17
-
-
3042677637
-
A membrane protein complex mediates retro-translocation from the ER lumen into the cytosol
-
Y. Ye A membrane protein complex mediates retro-translocation from the ER lumen into the cytosol Nature 429 2004 841 847
-
(2004)
Nature
, vol.429
, pp. 841-847
-
-
Ye, Y.1
-
18
-
-
0036083396
-
The ubiquitin-proteasome proteolytic pathway: Destruction for the sake of construction
-
M.H. Glickman, and A. Ciechanover The ubiquitin-proteasome proteolytic pathway: destruction for the sake of construction Physiol. Rev. 82 2002 373 428
-
(2002)
Physiol. Rev.
, vol.82
, pp. 373-428
-
-
Glickman, M.H.1
Ciechanover, A.2
-
19
-
-
0037343387
-
Recognition of a single transmembrane degron by sequential quality control checkpoints
-
L. Fayadat, and R.R. Kopito Recognition of a single transmembrane degron by sequential quality control checkpoints Mol. Biol. Cell 14 2003 1268 1278
-
(2003)
Mol. Biol. Cell
, vol.14
, pp. 1268-1278
-
-
Fayadat, L.1
Kopito, R.R.2
-
20
-
-
0028858161
-
Multiple proteolytic systems, including the proteasome, contribute to CFTR processing
-
T.J. Jensen Multiple proteolytic systems, including the proteasome, contribute to CFTR processing Cell 83 1995 129 135
-
(1995)
Cell
, vol.83
, pp. 129-135
-
-
Jensen, T.J.1
-
21
-
-
12144287602
-
Misfolding diverts CFTR from recycling to degradation: Quality control at early endosomes
-
M. Sharma Misfolding diverts CFTR from recycling to degradation: quality control at early endosomes J. Cell Biol. 164 2004 923 933
-
(2004)
J. Cell Biol.
, vol.164
, pp. 923-933
-
-
Sharma, M.1
-
22
-
-
2442451126
-
Misfolded proteins are sorted by a sequential checkpoint mechanism of ER quality control
-
S. Vashist, and D.T. Ng Misfolded proteins are sorted by a sequential checkpoint mechanism of ER quality control J. Cell Biol. 165 2004 41 52
-
(2004)
J. Cell Biol.
, vol.165
, pp. 41-52
-
-
Vashist, S.1
Ng, D.T.2
-
23
-
-
0035875665
-
The KDEL receptor mediates a retrieval mechanism that contributes to quality control at the endoplasmic reticulum
-
K. Yamamoto The KDEL receptor mediates a retrieval mechanism that contributes to quality control at the endoplasmic reticulum EMBO J. 20 2001 3082 3091
-
(2001)
EMBO J.
, vol.20
, pp. 3082-3091
-
-
Yamamoto, K.1
-
24
-
-
0032584722
-
Protein folding stability can determine the efficiency of escape from endoplasmic reticulum quality control
-
J.M. Kowalski Protein folding stability can determine the efficiency of escape from endoplasmic reticulum quality control J. Biol. Chem. 273 1998 19453 19458
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 19453-19458
-
-
Kowalski, J.M.1
-
25
-
-
0032477891
-
Secretion efficiency in Saccharomyces cerevisiae of bovine pancreatic trypsin inhibitor mutants lacking disulfide bonds is correlated with thermodynamic stability
-
J.M. Kowalski Secretion efficiency in Saccharomyces cerevisiae of bovine pancreatic trypsin inhibitor mutants lacking disulfide bonds is correlated with thermodynamic stability Biochemistry 37 1998 1264 1273
-
(1998)
Biochemistry
, vol.37
, pp. 1264-1273
-
-
Kowalski, J.M.1
-
26
-
-
0037166252
-
Engineering-enhanced protein secretory expression in yeast with application to insulin
-
T. Kjeldsen Engineering-enhanced protein secretory expression in yeast with application to insulin J. Biol. Chem. 277 2002 18245 18248
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 18245-18248
-
-
Kjeldsen, T.1
-
27
-
-
0035937847
-
Conformational and temperature-sensitive stability defects of the Δf508 cystic fibrosis transmembrane conductance regulator in post-endoplasmic reticulum compartments
-
M. Sharma Conformational and temperature-sensitive stability defects of the ΔF508 cystic fibrosis transmembrane conductance regulator in post-endoplasmic reticulum compartments J. Biol. Chem. 276 2001 8942 8950
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 8942-8950
-
-
Sharma, M.1
-
28
-
-
0035947777
-
COOH-terminal truncations promote proteasome-dependent degradation of mature cystic fibrosis transmembrane conductance regulator from post-Golgi compartments
-
M. Benharouga COOH-terminal truncations promote proteasome-dependent degradation of mature cystic fibrosis transmembrane conductance regulator from post-Golgi compartments J. Cell Biol. 153 2001 957 970
-
(2001)
J. Cell Biol.
, vol.153
, pp. 957-970
-
-
Benharouga, M.1
-
29
-
-
0035056623
-
2a-adrenergic receptor conformational stability and cell-surface turnover
-
2a-adrenergic receptor conformational stability and cell-surface turnover Mol. Pharmacol. 59 2001 929 938
-
(2001)
Mol. Pharmacol.
, vol.59
, pp. 929-938
-
-
Wilson, M.H.1
-
30
-
-
0037072934
-
A rhodopsin mutant linked to autosomal dominant retinitis pigmentosa is prone to aggregate and interacts with the ubiquitin proteasome system
-
M.E. Illing A rhodopsin mutant linked to autosomal dominant retinitis pigmentosa is prone to aggregate and interacts with the ubiquitin proteasome system J. Biol. Chem. 277 2002 34150 34160
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 34150-34160
-
-
Illing, M.E.1
-
31
-
-
0029943263
-
Structure and function in rhodopsin: Correct folding and misfolding in two point mutants in the intradiscal domain of rhodopsin identified in retinitis pigmentosa
-
X. Liu Structure and function in rhodopsin: correct folding and misfolding in two point mutants in the intradiscal domain of rhodopsin identified in retinitis pigmentosa Proc. Natl. Acad. Sci. U. S. A. 93 1996 4554 4559
-
(1996)
Proc. Natl. Acad. Sci. U. S. A.
, vol.93
, pp. 4554-4559
-
-
Liu, X.1
-
32
-
-
0038529723
-
Pharmacological chaperone-mediated in vivo folding and stabilization of the P23H-opsin mutant associated with autosomal dominant retinitis pigmentosa
-
S.M. Noorwez Pharmacological chaperone-mediated in vivo folding and stabilization of the P23H-opsin mutant associated with autosomal dominant retinitis pigmentosa J. Biol. Chem. 278 2003 14442 14450
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 14442-14450
-
-
Noorwez, S.M.1
-
33
-
-
1942469395
-
Retinoids assist the cellular folding of the autosomal dominant retinitis pigmentosa opsin mutant P23H
-
S.M. Noorwez Retinoids assist the cellular folding of the autosomal dominant retinitis pigmentosa opsin mutant P23H J. Biol. Chem. 279 2004 16278 16284
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 16278-16284
-
-
Noorwez, S.M.1
-
34
-
-
0025076114
-
Empty MHC class I molecules come out in the cold
-
H.G. Ljunggren Empty MHC class I molecules come out in the cold Nature 346 1990 476 480
-
(1990)
Nature
, vol.346
, pp. 476-480
-
-
Ljunggren, H.G.1
-
35
-
-
0031006695
-
Localization and suppression of a kinetic defect in cystic fibrosis transmembrane conductance regulator folding
-
B.H. Qu Localization and suppression of a kinetic defect in cystic fibrosis transmembrane conductance regulator folding J. Biol. Chem. 272 1997 15739 15744
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 15739-15744
-
-
Qu, B.H.1
-
37
-
-
10744230777
-
Structure of nucleotide-binding domain 1 of the cystic fibrosis transmembrane conductance regulator
-
H.A. Lewis Structure of nucleotide-binding domain 1 of the cystic fibrosis transmembrane conductance regulator EMBO J. 23 2004 282 293
-
(2004)
EMBO J.
, vol.23
, pp. 282-293
-
-
Lewis, H.A.1
-
38
-
-
0037008685
-
Introduction of the most common cystic fibrosis mutation (ΔF508) into human P-glycoprotein disrupts packing of the transmembrane segments
-
T.W. Loo Introduction of the most common cystic fibrosis mutation (ΔF508) into human P-glycoprotein disrupts packing of the transmembrane segments J. Biol. Chem. 277 2002 27585 27588
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 27585-27588
-
-
Loo, T.W.1
-
39
-
-
0036629253
-
Protein quality control: U-box-containing E3 ubiquitin ligases join the fold
-
D.M. Cyr Protein quality control: U-box-containing E3 ubiquitin ligases join the fold Trends Biochem. Sci. 27 2002 368 375
-
(2002)
Trends Biochem. Sci.
, vol.27
, pp. 368-375
-
-
Cyr, D.M.1
-
40
-
-
0038779355
-
Glycopeptide specificity of the secretory protein folding sensor UDP-glucose glycoprotein:glucosyltransferase
-
S.C. Taylor Glycopeptide specificity of the secretory protein folding sensor UDP-glucose glycoprotein:glucosyltransferase EMBO Rep. 4 2003 405 411
-
(2003)
EMBO Rep.
, vol.4
, pp. 405-411
-
-
Taylor, S.C.1
-
41
-
-
0742322956
-
The ER protein folding sensor UDP-glucose glycoprotein- glucosyltransferase modifies substrates distant to local changes in glycoprotein conformation
-
S.C. Taylor The ER protein folding sensor UDP-glucose glycoprotein-glucosyltransferase modifies substrates distant to local changes in glycoprotein conformation Nat. Struct. Mol. Biol. 11 2004 128 134
-
(2004)
Nat. Struct. Mol. Biol.
, vol.11
, pp. 128-134
-
-
Taylor, S.C.1
-
42
-
-
0038037820
-
Role of calnexin in the glycan-independent quality control of proteolipid protein
-
E. Swanton Role of calnexin in the glycan-independent quality control of proteolipid protein EMBO J. 22 2003 2948 2958
-
(2003)
EMBO J.
, vol.22
, pp. 2948-2958
-
-
Swanton, E.1
-
43
-
-
0036702298
-
ER-associated degradation in protein quality control and cellular regulation
-
R.Y. Hampton ER-associated degradation in protein quality control and cellular regulation Curr. Opin. Cell Biol. 14 2002 476 482
-
(2002)
Curr. Opin. Cell Biol.
, vol.14
, pp. 476-482
-
-
Hampton, R.Y.1
-
44
-
-
4644243461
-
Ubiquitin is conjugated by membrane ubiquitin ligase to three sites, including N-terminus, in transmembrane region of mammalian 3-hydroxy-3- methylglutaryl coenzyme a reductase: Implications for sterol-regulated enzyme degradation
-
R. Doolman Ubiquitin is conjugated by membrane ubiquitin ligase to three sites, including N-terminus, in transmembrane region of mammalian 3-hydroxy-3-methylglutaryl coenzyme a reductase: implications for sterol-regulated enzyme degradation J. Biol. Chem. 279 2004 38184 38193
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 38184-38193
-
-
Doolman, R.1
-
45
-
-
0036166924
-
A transmembrane ubiquitin ligase required to sort membrane proteins into multivesicular bodies
-
F. Reggiori, and H.R. Pelham A transmembrane ubiquitin ligase required to sort membrane proteins into multivesicular bodies Nat. Cell Biol. 4 2002 117 123
-
(2002)
Nat. Cell Biol.
, vol.4
, pp. 117-123
-
-
Reggiori, F.1
Pelham, H.R.2
-
46
-
-
1942439642
-
Bsd2 binds the ubiquitin ligase Rsp5 and mediates the ubiquitination of transmembrane proteins
-
E.H. Hettema Bsd2 binds the ubiquitin ligase Rsp5 and mediates the ubiquitination of transmembrane proteins EMBO J. 23 2004 1279 1288
-
(2004)
EMBO J.
, vol.23
, pp. 1279-1288
-
-
Hettema, E.H.1
-
47
-
-
0037099080
-
The cellular fate of mutant rhodopsin: Quality control, degradation and aggresome formation
-
R.S. Saliba The cellular fate of mutant rhodopsin: quality control, degradation and aggresome formation J. Cell Sci. 115 2002 2907 2918
-
(2002)
J. Cell Sci.
, vol.115
, pp. 2907-2918
-
-
Saliba, R.S.1
-
48
-
-
3042800569
-
Human loss-of-function gonadotropin-releasing hormone receptor mutants retain wild-type receptors in the endoplasmic reticulum: Molecular basis of the dominant-negative effect
-
S.P. Brothers Human loss-of-function gonadotropin-releasing hormone receptor mutants retain wild-type receptors in the endoplasmic reticulum: molecular basis of the dominant-negative effect Mol. Endocrinol. 18 2004 1787 1797
-
(2004)
Mol. Endocrinol.
, vol.18
, pp. 1787-1797
-
-
Brothers, S.P.1
-
49
-
-
0038637206
-
Dominant-negative action of disease-causing gonadotropin-releasing hormone receptor (GnRHR) mutants: A trait that potentially coevolved with decreased plasma membrane expression of GnRHR in humans
-
A. Leanos-Miranda Dominant-negative action of disease-causing gonadotropin-releasing hormone receptor (GnRHR) mutants: a trait that potentially coevolved with decreased plasma membrane expression of GnRHR in humans J. Clin. Endocrinol. Metab. 88 2003 3360 3367
-
(2003)
J. Clin. Endocrinol. Metab.
, vol.88
, pp. 3360-3367
-
-
Leanos-Miranda, A.1
-
50
-
-
3042540232
-
Pharmacological chaperones: Potential treatment for conformational diseases
-
V. Bernier Pharmacological chaperones: potential treatment for conformational diseases Trends Endocrinol. Metab. 15 2004 222 228
-
(2004)
Trends Endocrinol. Metab.
, vol.15
, pp. 222-228
-
-
Bernier, V.1
-
51
-
-
0034421921
-
Pharmacological chaperones: A new twist on receptor folding
-
J.P. Morello Pharmacological chaperones: a new twist on receptor folding Trends Pharmacol. Sci. 21 2000 466 469
-
(2000)
Trends Pharmacol. Sci.
, vol.21
, pp. 466-469
-
-
Morello, J.P.1
-
52
-
-
0037113890
-
A conditional mutation affecting localization of the Menkes disease copper ATPase. Suppression by copper supplementation
-
B.E. Kim A conditional mutation affecting localization of the Menkes disease copper ATPase. Suppression by copper supplementation J. Biol. Chem. 277 2002 44079 44084
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 44079-44084
-
-
Kim, B.E.1
-
53
-
-
0037007201
-
Ligands act as pharmacological chaperones and increase the efficiency of δ opioid receptor maturation
-
U.E. Petaja-Repo Ligands act as pharmacological chaperones and increase the efficiency of δ opioid receptor maturation EMBO J. 21 2002 1628 1637
-
(2002)
EMBO J.
, vol.21
, pp. 1628-1637
-
-
Petaja-Repo, U.E.1
-
54
-
-
0035830863
-
Newly synthesized human δ opioid receptors retained in the endoplasmic reticulum are retrotranslocated to the cytosol, deglycosylated, ubiquitinated, and degraded by the proteasome
-
U.E. Petaja-Repo Newly synthesized human δ opioid receptors retained in the endoplasmic reticulum are retrotranslocated to the cytosol, deglycosylated, ubiquitinated, and degraded by the proteasome J. Biol. Chem. 276 2001 4416 4423
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 4416-4423
-
-
Petaja-Repo, U.E.1
-
55
-
-
0034607918
-
Export from the endoplasmic reticulum represents the limiting step in the maturation and cell surface expression of the human δ opioid receptor
-
U.E. Petaja-Repo Export from the endoplasmic reticulum represents the limiting step in the maturation and cell surface expression of the human δ opioid receptor J. Biol. Chem. 275 2000 13727 13736
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 13727-13736
-
-
Petaja-Repo, U.E.1
-
56
-
-
3042788953
-
Intracellularly located misfolded glycoprotein hormone receptors associate with different chaperone proteins than their cognate wild-type receptors
-
D. Mizrachi, and D.L. Segaloff Intracellularly located misfolded glycoprotein hormone receptors associate with different chaperone proteins than their cognate wild-type receptors Mol. Endocrinol. 18 2004 1768 1777
-
(2004)
Mol. Endocrinol.
, vol.18
, pp. 1768-1777
-
-
Mizrachi, D.1
Segaloff, D.L.2
-
57
-
-
0012999148
-
Interaction of Hsp90 with the nascent form of the mutant epidermal growth factor receptor EGFRvIII
-
S.J. Lavictoire Interaction of Hsp90 with the nascent form of the mutant epidermal growth factor receptor EGFRvIII J. Biol. Chem. 278 2003 5292 5299
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 5292-5299
-
-
Lavictoire, S.J.1
-
58
-
-
0033559258
-
The Hdj-2/Hsc70 chaperone pair facilitates early steps in CFTR biogenesis
-
G.C. Meacham The Hdj-2/Hsc70 chaperone pair facilitates early steps in CFTR biogenesis EMBO J. 18 1999 1492 1505
-
(1999)
EMBO J.
, vol.18
, pp. 1492-1505
-
-
Meacham, G.C.1
-
59
-
-
0032491397
-
The mechanism underlying cystic fibrosis transmembrane conductance regulator transport from the endoplasmic reticulum to the proteasome includes Sec61β and a cytosolic, deglycosylated intermediary
-
Z. Bebok The mechanism underlying cystic fibrosis transmembrane conductance regulator transport from the endoplasmic reticulum to the proteasome includes Sec61β and a cytosolic, deglycosylated intermediary J. Biol. Chem. 273 1998 29873 29878
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 29873-29878
-
-
Bebok, Z.1
-
60
-
-
0035818999
-
The AAA ATPase Cdc48/p97 and its partners transport proteins from the ER into the cytosol
-
Y. Ye The AAA ATPase Cdc48/p97 and its partners transport proteins from the ER into the cytosol Nature 414 2001 652 656
-
(2001)
Nature
, vol.414
, pp. 652-656
-
-
Ye, Y.1
-
61
-
-
0035142877
-
The Hsc70 co-chaperone CHIP targets immature CFTR for proteasomal degradation
-
G.C. Meacham The Hsc70 co-chaperone CHIP targets immature CFTR for proteasomal degradation Nat. Cell Biol. 3 2001 100 105
-
(2001)
Nat. Cell Biol.
, vol.3
, pp. 100-105
-
-
Meacham, G.C.1
-
62
-
-
18444413218
-
E3 ubiquitin ligase that recognizes sugar chains
-
Y. Yoshida E3 ubiquitin ligase that recognizes sugar chains Nature 418 2002 438 442
-
(2002)
Nature
, vol.418
, pp. 438-442
-
-
Yoshida, Y.1
-
63
-
-
0242321836
-
Fbs2 is a new member of the E3 ubiquitin ligase family that recognizes sugar chains
-
Y. Yoshida Fbs2 is a new member of the E3 ubiquitin ligase family that recognizes sugar chains J. Biol. Chem. 278 2003 43877 43884
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 43877-43884
-
-
Yoshida, Y.1
-
64
-
-
0035203949
-
Correction of delF508-CFTR activity with benzo(c)quinolizinium compounds through facilitation of its processing in cystic fibrosis airway cells
-
R.L. Dormer Correction of delF508-CFTR activity with benzo(c) quinolizinium compounds through facilitation of its processing in cystic fibrosis airway cells J. Cell Sci. 114 2001 4073 4081
-
(2001)
J. Cell Sci.
, vol.114
, pp. 4073-4081
-
-
Dormer, R.L.1
-
65
-
-
0035827680
-
Novel CFTR chloride channel activators identified by screening of combinatorial libraries based on flavone and benzoquinolizinium lead compounds
-
L.J. Galietta Novel CFTR chloride channel activators identified by screening of combinatorial libraries based on flavone and benzoquinolizinium lead compounds J. Biol. Chem. 276 2001 19723 19728
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 19723-19728
-
-
Galietta, L.J.1
-
66
-
-
0029099301
-
P-glycoprotein. Associations between domains and between domains and molecular chaperones
-
T.W. Loo, and D.M. Clarke P-glycoprotein. Associations between domains and between domains and molecular chaperones J. Biol. Chem. 270 1995 21839 21844
-
(1995)
J. Biol. Chem.
, vol.270
, pp. 21839-21844
-
-
Loo, T.W.1
Clarke, D.M.2
-
67
-
-
1542376209
-
Missense mutations in transmembrane domains of proteins: Phenotypic propensity of polar residues for human disease
-
A.W. Partridge Missense mutations in transmembrane domains of proteins: phenotypic propensity of polar residues for human disease Proteins 54 2004 648 656
-
(2004)
Proteins
, vol.54
, pp. 648-656
-
-
Partridge, A.W.1
-
68
-
-
0033615646
-
Correction of defective protein trafficking of a mutant HERG potassium channel in human long QT syndrome. Pharmacological and temperature effects
-
Z. Zhou Correction of defective protein trafficking of a mutant HERG potassium channel in human long QT syndrome. Pharmacological and temperature effects J. Biol. Chem. 274 1999 31123 31126
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 31123-31126
-
-
Zhou, Z.1
-
69
-
-
0034118221
-
Pharmacological chaperones rescue cell-surface expression and function of misfolded V2 vasopressin receptor mutants
-
J.P. Morello Pharmacological chaperones rescue cell-surface expression and function of misfolded V2 vasopressin receptor mutants J. Clin. Invest. 105 2000 887 895
-
(2000)
J. Clin. Invest.
, vol.105
, pp. 887-895
-
-
Morello, J.P.1
-
70
-
-
0036322898
-
Rescue of hypogonadotropic hypogonadism-causing and manufactured GnRH receptor mutants by a specific protein-folding template: Misrouted proteins as a novel disease etiology and therapeutic target
-
J.A. Janovick Rescue of hypogonadotropic hypogonadism-causing and manufactured GnRH receptor mutants by a specific protein-folding template: misrouted proteins as a novel disease etiology and therapeutic target J. Clin. Endocrinol. Metab. 87 2002 3255 3262
-
(2002)
J. Clin. Endocrinol. Metab.
, vol.87
, pp. 3255-3262
-
-
Janovick, J.A.1
-
71
-
-
0344059035
-
Structure-activity relations of successful pharmacologic chaperones for rescue of naturally occurring and manufactured mutants of the gonadotropin-releasing hormone receptor
-
J.A. Janovick Structure-activity relations of successful pharmacologic chaperones for rescue of naturally occurring and manufactured mutants of the gonadotropin-releasing hormone receptor J. Pharmacol. Exp. Ther. 305 2003 608 614
-
(2003)
J. Pharmacol. Exp. Ther.
, vol.305
, pp. 608-614
-
-
Janovick, J.A.1
-
72
-
-
0032967642
-
Nicotinic acetylcholine receptor at 4.6 Å resolution: Transverse tunnels in the channel wall
-
A. Miyazawa Nicotinic acetylcholine receptor at 4.6 Å resolution: transverse tunnels in the channel wall J. Mol. Biol. 288 1999 765 786
-
(1999)
J. Mol. Biol.
, vol.288
, pp. 765-786
-
-
Miyazawa, A.1
|