Limited evidence for adaptive evolution and functional effect of allelic variation at rs702424 in the promoter of the TAS2R16 bitter taste receptor gene in Africa

Journal of Human Genetics

Volumn 59, Issue 6, 2014, Pages 349-352

  Campbell, Michael C ^a   Ranciaro, Alessia ^a   Zinshteyn, Daniel ^a,j   Rawlings Goss, Renata ^a   Hirbo, Jibril ^a   Thompson, Simon ^a   Woldemeskel, Dawit ^a,b   Froment, Alain ^c   Omar, Sabah A ^d   Bodo, Jean Marie ^e   Nyambo, Thomas ^f   Belay, Gurja ^b   Drayna, Dennis ^g   Breslin, Paul A S ^h,i   Tishkoff, Sarah A ^a  

^a UNIVERSITY OF PENNSYLVANIA   (United States)

^b ADDIS ABABA UNIVERSITY   (Ethiopia)

^c INSTITUT DE RECHERCHE POUR LE DÉVELOPPEMENT   (France)

^d KENYA MEDICAL RESEARCH INSTITUTE   (Kenya)

^e INSTITUTE OF AGRICULTURAL RESEARCH FOR DEVELOPMENT IRAD   (Cameroon)

^f MUHIMBILI UNIVERSITY OF HEALTH AND ALLIED SCIENCES   (Tanzania)

^g NATIONAL INSTITUTE ON DEAFNESS AND OTHER COMMUNICATION DISORDERS   (United States)

^h MONELL CHEMICAL SENSES CENTER   (United States)

ⁱ RUTGERS UNIVERSITY   (United States)

^j Department of Nutritional Sciences Rutgers University ^*  (United States)

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Author keywords

[No Author keywords available]

Indexed keywords

SALICIN; ANTIINFLAMMATORY AGENT; BENZYL ALCOHOL DERIVATIVE; G PROTEIN COUPLED RECEPTOR; GLUCOSIDE; TASTE RECEPTORS, TYPE 2;

AFRICA; ALLELE; ARTICLE; BITTER TASTE; EXON; GENE FREQUENCY; GENETIC ASSOCIATION; GENETIC VARIABILITY; GENOTYPE; HAPLOTYPE; HOMOZYGOSITY; HUMAN; MAJOR CLINICAL STUDY; PHENOTYPE; PROMOTER REGION; RECEPTOR GENE; SINGLE NUCLEOTIDE POLYMORPHISM; TAS2R16 GENE; GENETIC ASSOCIATION STUDY; GENETICS; METABOLISM; MOLECULAR EVOLUTION; TASTE;

AFRICA, EASTERN; ALLELES; ANTI-INFLAMMATORY AGENTS; BENZYL ALCOHOLS; EVOLUTION, MOLECULAR; GENETIC ASSOCIATION STUDIES; GLUCOSIDES; HUMANS; POLYMORPHISM, SINGLE NUCLEOTIDE; PROMOTER REGIONS, GENETIC; RECEPTORS, G-PROTEIN-COUPLED; TASTE PERCEPTION;

EID: 84903137414     PISSN: 14345161     EISSN: 1435232X     Source Type: Journal    
DOI: 10.1038/jhg.2014.29     Document Type: Article

References (16)

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