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Volumn 1420, Issue 1, 2018, Pages 5-25

Recent developments in understanding the role of the gut microbiota in brain health and disease

Author keywords

aging; behavior; brain; diet; microbiota; neurodegeneration

Indexed keywords

ALCOHOL; CANNABIS; COCAINE; PREBIOTIC AGENT; PROBIOTIC AGENT;

EID: 85048193971     PISSN: 00778923     EISSN: 17496632     Source Type: Book Series    
DOI: 10.1111/nyas.13416     Document Type: Review
Times cited : (245)

References (153)
  • 1
    • 84899887691 scopus 로고    scopus 로고
    • Recycling Metchnikoff: probiotics, the intestinal microbiome and the quest for long life
    • Mackowiak, P.A. 2013. Recycling Metchnikoff: probiotics, the intestinal microbiome and the quest for long life. Front. Public Health 1: 52.
    • (2013) Front. Public Health , vol.1 , pp. 52
    • Mackowiak, P.A.1
  • 2
    • 78049396557 scopus 로고
    • The treatment of melancholia by the lactic acid Bacillus
    • Phillips, J.G.P. 1910. The treatment of melancholia by the lactic acid Bacillus. Br. J. Psychiatry 56: 422–431.
    • (1910) Br. J. Psychiatry , vol.56 , pp. 422-431
    • Phillips, J.G.P.1
  • 3
    • 84875313316 scopus 로고    scopus 로고
    • Intestinal microbiota, probiotics and mental health: from Metchnikoff to modern advances: part II—contemporary contextual research
    • Bested, A.C., A.C. Logan & E.M. Selhub. 2013. Intestinal microbiota, probiotics and mental health: from Metchnikoff to modern advances: part II—contemporary contextual research. Gut Pathog. 5: 3.
    • (2013) Gut Pathog , vol.5 , pp. 3
    • Bested, A.C.1    Logan, A.C.2    Selhub, E.M.3
  • 4
    • 84978863659 scopus 로고    scopus 로고
    • May the force be with you: the light and dark sides of the microbiota–gut–brain axis in neuropsychiatry
    • Sherwin, E., K.V. Sandhu, T.G. Dinan & J.F. Cryan. 2016. May the force be with you: the light and dark sides of the microbiota–gut–brain axis in neuropsychiatry. CNS Drugs 30: 1019–1041.
    • (2016) CNS Drugs , vol.30 , pp. 1019-1041
    • Sherwin, E.1    Sandhu, K.V.2    Dinan, T.G.3    Cryan, J.F.4
  • 5
    • 84944446673 scopus 로고    scopus 로고
    • Breaking down the barriers: the gut microbiome, intestinal permeability and stress-related psychiatric
    • Kelly, J.R., P.J. Kennedy, J.F. Cryan, T.G. Dinan, et al. 2015. Breaking down the barriers: the gut microbiome, intestinal permeability and stress-related psychiatric. Front. Cell. Neurosci. 9: 392.
    • (2015) Front. Cell. Neurosci. , vol.9 , pp. 392
    • Kelly, J.R.1    Kennedy, P.J.2    Cryan, J.F.3    Dinan, T.G.4
  • 6
    • 84872296174 scopus 로고    scopus 로고
    • Voices from within: gut microbes and the CNS
    • Forsythe, P. & W.A. Kunze. 2013. Voices from within: gut microbes and the CNS. Cell. Mol. Life Sci. 70: 55–69.
    • (2013) Cell. Mol. Life Sci. , vol.70 , pp. 55-69
    • Forsythe, P.1    Kunze, W.A.2
  • 7
    • 84929310699 scopus 로고    scopus 로고
    • Control of brain development, function, and behavior by the microbiome
    • Sampson, T.R. & S.K. Mazmanian. 2015. Control of brain development, function, and behavior by the microbiome. Cell Host Microbe 17: 565–576.
    • (2015) Cell Host Microbe , vol.17 , pp. 565-576
    • Sampson, T.R.1    Mazmanian, S.K.2
  • 8
    • 84994887788 scopus 로고    scopus 로고
    • Psychobiotics and the manipulation of bacteria–gut–brain signals
    • Sarkar, A., S.M. Lehto, S. Harty, et al. 2016. Psychobiotics and the manipulation of bacteria–gut–brain signals. Trends Neurosci. 39: 763–781
    • (2016) Trends Neurosci , vol.39 , pp. 763-781
    • Sarkar, A.1    Lehto, S.M.2    Harty, S.3
  • 9
  • 11
    • 84909979667 scopus 로고    scopus 로고
    • Gut microbes and the brain: paradigm shift in neuroscience
    • Mayer, X.E.A., R. Knight, S.K. Mazmanian, et al. 2014. Gut microbes and the brain: paradigm shift in neuroscience. J. Neurosci. 34: 15490–15496.
    • (2014) J. Neurosci. , vol.34 , pp. 15490-15496
    • Mayer, X.E.A.1    Knight, R.2    Mazmanian, S.K.3
  • 13
    • 85029714663 scopus 로고    scopus 로고
    • Differences in gut microbial composition correlate with regional brain volumes in irritable bowel syndrome
    • Labus, J.S., E.B. Hollister, J. Jacobs, et al. 2017. Differences in gut microbial composition correlate with regional brain volumes in irritable bowel syndrome. Microbiome 5: 1–17.
    • (2017) Microbiome , vol.5 , pp. 1-17
    • Labus, J.S.1    Hollister, E.B.2    Jacobs, J.3
  • 15
  • 17
    • 84912141027 scopus 로고    scopus 로고
    • Serotonin, tryptophan metabolism and the brain–gut–microbiome axis
    • O'Mahony, S.M., G. Clarke, Y.E. Borre, et al. 2015. Serotonin, tryptophan metabolism and the brain–gut–microbiome axis. Behav. Brain Res. 277: 32–48.
    • (2015) Behav. Brain Res. , vol.277 , pp. 32-48
    • O'Mahony, S.M.1    Clarke, G.2    Borre, Y.E.3
  • 18
    • 84886699737 scopus 로고    scopus 로고
    • Psychobiotics highlight the pathways to happiness
    • Burnet, P.W.J. & P.J. Cowen. 2013. Psychobiotics highlight the pathways to happiness. Biol. Psychiatry 74: 708–709.
    • (2013) Biol. Psychiatry , vol.74 , pp. 708-709
    • Burnet, P.W.J.1    Cowen, P.J.2
  • 19
    • 85008263188 scopus 로고    scopus 로고
    • Microbiota and neurological disorders: a gut feeling
    • Moos, W.H., D.V. Faller, D.N. Harpp, et al. 2016. Microbiota and neurological disorders: a gut feeling. Biores. Open Access 5: 137–145.
    • (2016) Biores. Open Access , vol.5 , pp. 137-145
    • Moos, W.H.1    Faller, D.V.2    Harpp, D.N.3
  • 21
    • 84948992933 scopus 로고    scopus 로고
    • Gut microbiota and aging
    • O'Toole, P.W. & I.B. Jeffery. 2015. Gut microbiota and aging. Science 350: 1214–1216.
    • (2015) Science , vol.350 , pp. 1214-1216
    • O'Toole, P.W.1    Jeffery, I.B.2
  • 22
    • 84992159188 scopus 로고    scopus 로고
    • Gut microbiota signatures of longevity
    • Kong, F., Y. Hua, B. Zeng, et al. 2016. Gut microbiota signatures of longevity. Curr. Biol. 26: R832–R833.
    • (2016) Curr. Biol. , vol.26 , pp. R832-R833
    • Kong, F.1    Hua, Y.2    Zeng, B.3
  • 23
    • 85009973266 scopus 로고    scopus 로고
    • Gut microbiota: a player in aging and a target for anti-aging intervention
    • Vaiserman, A.M., A.K. Koliada & F. Marotta. 2017. Gut microbiota: a player in aging and a target for anti-aging intervention. Ageing Res. Rev. 35: 36–45.
    • (2017) Ageing Res. Rev. , vol.35 , pp. 36-45
    • Vaiserman, A.M.1    Koliada, A.K.2    Marotta, F.3
  • 24
  • 25
    • 85013843627 scopus 로고    scopus 로고
    • Revisiting Metchnikoff: age-related alterations in microbiota-gut–brain axis in the mouse
    • Scott, K.A., M. Ida, V.L. Peterson, et al. 2017. Revisiting Metchnikoff: age-related alterations in microbiota-gut–brain axis in the mouse. Brain Behav. Immun. https://doi.org/10.1016/j.bbi.2017.02.004.
    • (2017) Brain Behav. Immun.
    • Scott, K.A.1    Ida, M.2    Peterson, V.L.3
  • 26
    • 84917690894 scopus 로고    scopus 로고
    • Microbiota and the gut–liver axis: bacterial translocation, inflammation and infection in cirrhosis
    • Giannelli, V., V. Di Gregorio, V. Iebba, et al. 2014. Microbiota and the gut–liver axis: bacterial translocation, inflammation and infection in cirrhosis. WorldJ. Gastroenterol. 20: 16795–16810.
    • (2014) WorldJ. Gastroenterol. , vol.20 , pp. 16795-16810
    • Giannelli, V.1    Di Gregorio, V.2    Iebba, V.3
  • 27
    • 84963976238 scopus 로고    scopus 로고
    • Aging and serum MCP-1 are associated with gut microbiome composition in a murine model
    • Conley, M.N., C.P. Wong, K.M. Duyck, et al. 2016. Aging and serum MCP-1 are associated with gut microbiome composition in a murine model. Peer J. 4: e1854.
    • (2016) Peer J , vol.4
    • Conley, M.N.1    Wong, C.P.2    Duyck, K.M.3
  • 28
    • 84954419818 scopus 로고    scopus 로고
    • Gut microbiota lipopolysaccharide accelerates inflamm-aging in mice
    • Kim, K.-A., J.-J. Jeong, S.-Y. Yoo & D.-H. Kim. 2016. Gut microbiota lipopolysaccharide accelerates inflamm-aging in mice. BMC Microbiol. 16: 9.
    • (2016) BMC Microbiol. , vol.16 , pp. 9
    • Kim, K.-A.1    Jeong, J.-J.2    Yoo, S.-Y.3    Kim, D.-H.4
  • 29
    • 85006733623 scopus 로고    scopus 로고
    • Anti-inflammaging effects of Lactobacillus brevis OW38 in aged mice
    • Jeong, J.-J., K.A. Kim, Y.-J. Hwang, et al. 2016. Anti-inflammaging effects of Lactobacillus brevis OW38 in aged mice. Benef. Microbes 7: 1–12.
    • (2016) Benef. Microbes , vol.7 , pp. 1-12
    • Jeong, J.-J.1    Kim, K.A.2    Hwang, Y.-J.3
  • 30
    • 85006324099 scopus 로고    scopus 로고
    • Modulation of gut microbiota and delayed immunosenescence as a result of syringaresinol consumption in middle-aged mice
    • Cho, S.-Y., J. Kim, J.H. Lee, et al. 2016. Modulation of gut microbiota and delayed immunosenescence as a result of syringaresinol consumption in middle-aged mice. Sci. Rep. 6: 39026.
    • (2016) Sci. Rep. , vol.6 , pp. 39026
    • Cho, S.-Y.1    Kim, J.2    Lee, J.H.3
  • 31
    • 85008870031 scopus 로고    scopus 로고
    • Gastrointestinal dysfunctions in Parkinson's disease: symptoms and treatments
    • Poirier, A.-A., B. Aubé, M. Côté, et al. 2016. Gastrointestinal dysfunctions in Parkinson's disease: symptoms and treatments. Parkinsons Dis. 2016: 6762528.
    • (2016) Parkinsons Dis. , vol.2016 , pp. 6762528
    • Poirier, A.-A.1    Aubé, B.2    Côté, M.3
  • 32
    • 84961266625 scopus 로고    scopus 로고
    • Microbiota–gut–brain signalling in Parkinson's disease: implications for non-motor symptoms
    • Felice, V.D., E.M. Quigley, A.M. Sullivan, et al. 2016. Microbiota–gut–brain signalling in Parkinson's disease: implications for non-motor symptoms. Parkinsonism Relat. Disord. 27: 1–8.
    • (2016) Parkinsonism Relat. Disord. , vol.27 , pp. 1-8
    • Felice, V.D.1    Quigley, E.M.2    Sullivan, A.M.3
  • 33
    • 82455206282 scopus 로고    scopus 로고
    • Increased intestinal permeability correlates with sigmoid mucosa alpha-synuclein staining and endotoxin exposure markers in early Parkinson's disease
    • Forsyth, C.B., K.M. Shannon, J.H. Kordower, et al. 2011. Increased intestinal permeability correlates with sigmoid mucosa alpha-synuclein staining and endotoxin exposure markers in early Parkinson's disease. PLoS One 6: e28032.
    • (2011) PLoS One , vol.6
    • Forsyth, C.B.1    Shannon, K.M.2    Kordower, J.H.3
  • 34
    • 84896717250 scopus 로고    scopus 로고
    • Accumulation of α-synuclein in the bowel of patients in the pre-clinical phase of Parkinson's disease
    • Hilton, D., M. Stephens, L. Kirk, et al. 2014. Accumulation of α-synuclein in the bowel of patients in the pre-clinical phase of Parkinson's disease. Acta Neuropathol. 127: 235–241.
    • (2014) Acta Neuropathol , vol.127 , pp. 235-241
    • Hilton, D.1    Stephens, M.2    Kirk, L.3
  • 35
    • 84922092995 scopus 로고    scopus 로고
    • Direct evidence of Parkinson pathology spread from the gastrointestinal tract to the brain in rats
    • Holmqvist, S., O. Chutna, L. Bousset, et al. 2014. Direct evidence of Parkinson pathology spread from the gastrointestinal tract to the brain in rats. Acta Neuropathol. 128: 805–820.
    • (2014) Acta Neuropathol , vol.128 , pp. 805-820
    • Holmqvist, S.1    Chutna, O.2    Bousset, L.3
  • 36
    • 84924577956 scopus 로고    scopus 로고
    • Gut microbiota are related to Parkinson's disease and clinical phenotype
    • Scheperjans, F., V. Aho, P.A.B. Pereira, et al. 2015. Gut microbiota are related to Parkinson's disease and clinical phenotype. Mov. Disord. 30: 350–358.
    • (2015) Mov. Disord. , vol.30 , pp. 350-358
    • Scheperjans, F.1    Aho, V.2    Pereira, P.A.B.3
  • 37
    • 85018307343 scopus 로고    scopus 로고
    • Functional implications of microbial and viral gut metagenome changes in early stage l-DOPA-naïve Parkinson's disease patients
    • Bedarf, J.R., F. Hildebrand, L.P. Coelho, et al. 2017. Functional implications of microbial and viral gut metagenome changes in early stage l-DOPA-naïve Parkinson's disease patients. Genome Med. 9: 1–13.
    • (2017) Genome Med , vol.9 , pp. 1-13
    • Bedarf, J.R.1    Hildebrand, F.2    Coelho, L.P.3
  • 38
    • 84941167046 scopus 로고    scopus 로고
    • Colonic bacterial composition in Parkinson's disease
    • Keshavarzian, A., S.J. Green, P.A. Engen, et al. 2015. Colonic bacterial composition in Parkinson's disease. Mov. Disord. 30: 1351–1360.
    • (2015) Mov. Disord. , vol.30 , pp. 1351-1360
    • Keshavarzian, A.1    Green, S.J.2    Engen, P.A.3
  • 39
    • 85013158306 scopus 로고    scopus 로고
    • Parkinson's disease and Parkinson's disease medications have distinct signatures of the gut microbiome
    • Hill-Burns, E.M., J.W. Debelius, J.T. Morton, et al. 2017. Parkinson's disease and Parkinson's disease medications have distinct signatures of the gut microbiome. Mov. Disord. 32: 739–749.
    • (2017) Mov. Disord. , vol.32 , pp. 739-749
    • Hill-Burns, E.M.1    Debelius, J.W.2    Morton, J.T.3
  • 40
    • 84994745714 scopus 로고    scopus 로고
    • Short chain fatty acids and gut microbiota differ between patients with Parkinson's disease and age-matched controls
    • Unger, M.M., J. Spiegel, K.-U. Dillmann, et al. 2016. Short chain fatty acids and gut microbiota differ between patients with Parkinson's disease and age-matched controls. Parkinsonism Relat. Disord. 32: 66–72.
    • (2016) Parkinsonism Relat. Disord. , vol.32 , pp. 66-72
    • Unger, M.M.1    Spiegel, J.2    Dillmann, K.-U.3
  • 41
    • 1842455106 scopus 로고    scopus 로고
    • Regulation of microglial inflammatory response by sodium butyrate and short-chain fatty acids
    • Huuskonen, J., T. Suuronen, T. Nuutinen, et al. 2004. Regulation of microglial inflammatory response by sodium butyrate and short-chain fatty acids. Br. J. Pharmacol. 141: 874–880.
    • (2004) Br. J. Pharmacol. , vol.141 , pp. 874-880
    • Huuskonen, J.1    Suuronen, T.2    Nuutinen, T.3
  • 42
    • 84883559371 scopus 로고    scopus 로고
    • The role of small intestinal bacterial overgrowth in Parkinson's disease
    • Fasano, A., F. Bove, M. Gabrielli, et al. 2013. The role of small intestinal bacterial overgrowth in Parkinson's disease. Mov. Disord. 28: 1241–1249.
    • (2013) Mov. Disord. , vol.28 , pp. 1241-1249
    • Fasano, A.1    Bove, F.2    Gabrielli, M.3
  • 43
    • 84963626535 scopus 로고    scopus 로고
    • Association between Parkinson's disease and Helicobacter pylori
    • Çamcı, G. & S. Oğuz. 2016. Association between Parkinson's disease and Helicobacter pylori. J. Clin. Neurol. 12: 147–150.
    • (2016) J. Clin. Neurol. , vol.12 , pp. 147-150
    • Çamcı, G.1    Oğuz, S.2
  • 44
    • 84925368160 scopus 로고    scopus 로고
    • Increased urinary indoxyl sulfate (indican): new insights into gut dysbiosis in Parkinson's disease
    • Cassani, E., M. Barichella, R. Cancello, et al. 2015. Increased urinary indoxyl sulfate (indican): new insights into gut dysbiosis in Parkinson's disease. Parkinsonism Relat. Disord. 21: 389–393.
    • (2015) Parkinsonism Relat. Disord. , vol.21 , pp. 389-393
    • Cassani, E.1    Barichella, M.2    Cancello, R.3
  • 45
    • 49749088770 scopus 로고    scopus 로고
    • Helicobacter hypothesis for idiopathic parkinsonism: before and beyond
    • Dobbs, R.J., S.M. Dobbs, C. Weller, et al. 2008. Helicobacter hypothesis for idiopathic parkinsonism: before and beyond. Helicobacter 13: 309–322.
    • (2008) Helicobacter , vol.13 , pp. 309-322
    • Dobbs, R.J.1    Dobbs, S.M.2    Weller, C.3
  • 46
    • 84911998490 scopus 로고    scopus 로고
    • Eradication of Helicobacter pylori infection improves levodopa action, clinical symptoms and quality of life in patients with Parkinson's disease
    • Hashim, H., S. Azmin, H. Razlan, et al. 2014. Eradication of Helicobacter pylori infection improves levodopa action, clinical symptoms and quality of life in patients with Parkinson's disease. PLoS One 9: e112330.
    • (2014) PLoS One , vol.9
    • Hashim, H.1    Azmin, S.2    Razlan, H.3
  • 47
    • 85001930733 scopus 로고    scopus 로고
    • Gut microbiota regulate motor deficits and neuroinflammation in a model of Parkinson's disease
    • e12
    • Sampson, T.R., J.W. Debelius, T. Thron, et al. 2016. Gut microbiota regulate motor deficits and neuroinflammation in a model of Parkinson's disease. Cell 167: 1469–1480. e12.
    • (2016) Cell , vol.167 , pp. 1469-1480
    • Sampson, T.R.1    Debelius, J.W.2    Thron, T.3
  • 48
    • 84933043202 scopus 로고    scopus 로고
    • Host microbiota constantly control maturation and function of microglia in the CNS
    • Erny, D., A.L. Hrabě de Angelis, D. Jaitin, et al. 2015. Host microbiota constantly control maturation and function of microglia in the CNS. Nat. Neurosci. 18: 965–977.
    • (2015) Nat. Neurosci. , vol.18 , pp. 965-977
    • Erny, D.1    Hrabě de Angelis, A.L.2    Jaitin, D.3
  • 49
    • 84993945111 scopus 로고    scopus 로고
    • Association of brain amyloidosis with pro-inflammatory gut bacterial taxa and peripheral inflammation markers in cognitively impaired elderly
    • Cattaneo, A., N. Cattane, S. Galluzzi, et al. 2017. Association of brain amyloidosis with pro-inflammatory gut bacterial taxa and peripheral inflammation markers in cognitively impaired elderly. Neurobiol. Aging 49: 60–68.
    • (2017) Neurobiol. Aging , vol.49 , pp. 60-68
    • Cattaneo, A.1    Cattane, N.2    Galluzzi, S.3
  • 50
    • 84999863217 scopus 로고    scopus 로고
    • Gram-negative bacterial molecules associate with Alzheimer disease pathology
    • Zhan, X., B. Stamova, L.W. Jin, et al. 2016. Gram-negative bacterial molecules associate with Alzheimer disease pathology. Neurology 87: 2324–2332.
    • (2016) Neurology , vol.87 , pp. 2324-2332
    • Zhan, X.1    Stamova, B.2    Jin, L.W.3
  • 51
    • 84925348854 scopus 로고    scopus 로고
    • Mechanisms of molecular mimicry involving the microbiota in neurodegeneration
    • Friedland, R.P. 2015. Mechanisms of molecular mimicry involving the microbiota in neurodegeneration. J. Alzheimers Dis. 45: 349–362.
    • (2015) J. Alzheimers Dis. , vol.45 , pp. 349-362
    • Friedland, R.P.1
  • 52
    • 85011954434 scopus 로고    scopus 로고
    • Reduction of Abeta amyloid pathology in APPPS1 transgenic mice in the absence of gut microbiota
    • Harach, T., N. Marungruang, N. Duthilleul, et al. 2017. Reduction of Abeta amyloid pathology in APPPS1 transgenic mice in the absence of gut microbiota. Sci. Rep. 7: 41802.
    • (2017) Sci. Rep. , vol.7 , pp. 41802
    • Harach, T.1    Marungruang, N.2    Duthilleul, N.3
  • 53
    • 84979276209 scopus 로고    scopus 로고
    • Antibiotic-induced perturbations in gut microbial diversity influences neuro-inflammation and amyloidosis in a murine model of Alzheimer's disease
    • Minter, M.R., C. Zhang, V. Leone, et al. 2016. Antibiotic-induced perturbations in gut microbial diversity influences neuro-inflammation and amyloidosis in a murine model of Alzheimer's disease. Sci. Rep. 6: 30028.
    • (2016) Sci. Rep. , vol.6 , pp. 30028
    • Minter, M.R.1    Zhang, C.2    Leone, V.3
  • 54
    • 85011343828 scopus 로고    scopus 로고
    • Altered gut microbiome composition and tryptic activity of the 5xFAD Alzheimer's mouse model
    • Brandscheid, C., F. Schuck, S. Reinhardt, et al. 2017. Altered gut microbiome composition and tryptic activity of the 5xFAD Alzheimer's mouse model. J. Alzheimers Dis. 56: 775–788.
    • (2017) J. Alzheimers Dis. , vol.56 , pp. 775-788
    • Brandscheid, C.1    Schuck, F.2    Reinhardt, S.3
  • 55
    • 84930179301 scopus 로고    scopus 로고
    • Role of intestinal microbiota in the generation of polyphenol-derived phenolic acid mediated attenuation of Alzheimer's disease beta-amyloid oligomerization
    • Wang, D., L. Ho, J. Faith, et al. 2015. Role of intestinal microbiota in the generation of polyphenol-derived phenolic acid mediated attenuation of Alzheimer's disease beta-amyloid oligomerization. Mol. Nutr. Food Res. 59: 1025–1040.
    • (2015) Mol. Nutr. Food Res. , vol.59 , pp. 1025-1040
    • Wang, D.1    Ho, L.2    Faith, J.3
  • 56
    • 84920563271 scopus 로고    scopus 로고
    • Modulation of intestinal microbiota by the probiotic VSL#3 resets brain gene expression and ameliorates the age-related deficit in LTP
    • Distrutti, E., J.-A. O'Reilly, C. McDonald, et al. 2014. Modulation of intestinal microbiota by the probiotic VSL#3 resets brain gene expression and ameliorates the age-related deficit in LTP. PLoS One 9: e106503.
    • (2014) PLoS One , vol.9
    • Distrutti, E.1    O'Reilly, J.-A.2    McDonald, C.3
  • 57
    • 85014829081 scopus 로고    scopus 로고
    • Altered intestinal permeability in patients with relapsing–remitting multiple sclerosis: a pilot study
    • Buscarinu, M.C., B. Cerasoli, V. Annibali, et al. 2017. Altered intestinal permeability in patients with relapsing–remitting multiple sclerosis: a pilot study. Mult. Scler. 23: 442–446.
    • (2017) Mult. Scler. , vol.23 , pp. 442-446
    • Buscarinu, M.C.1    Cerasoli, B.2    Annibali, V.3
  • 60
    • 84963682759 scopus 로고    scopus 로고
    • Regulation of prefrontal cortex myelination by the microbiota
    • Hoban, A.E., R.M. Stilling, F.J. Ryan, et al. 2016. Regulation of prefrontal cortex myelination by the microbiota. Transl. Psychiatry 6: e774.
    • (2016) Transl. Psychiatry , vol.6
    • Hoban, A.E.1    Stilling, R.M.2    Ryan, F.J.3
  • 61
    • 84971575056 scopus 로고    scopus 로고
    • Microbiota-driven transcriptional changes in prefrontal cortex override genetic differences in social behavior
    • Gacias, M., S. Gaspari, P.M.G. Santos, et al. 2016. Microbiota-driven transcriptional changes in prefrontal cortex override genetic differences in social behavior. Elife 5: 1–27.
    • (2016) Elife , vol.5 , pp. 1-27
    • Gacias, M.1    Gaspari, S.2    Santos, P.M.G.3
  • 62
    • 79952748674 scopus 로고    scopus 로고
    • Proinflammatory T-cell responses to gut microbiota promote experimental autoimmune encephalomyelitis
    • Kyung, Y., J.S. Menezes, Y. Umesaki & S.K. Mazmanian. 2011. Proinflammatory T-cell responses to gut microbiota promote experimental autoimmune encephalomyelitis. Proc. Natl. Acad. Sci. U.S.A. 108: 4615–4622.
    • (2011) Proc. Natl. Acad. Sci. U.S.A. , vol.108 , pp. 4615-4622
    • Kyung, Y.1    Menezes, J.S.2    Umesaki, Y.3    Mazmanian, S.K.4
  • 63
    • 84958636544 scopus 로고    scopus 로고
    • TNFR2 deficiency acts in concert with gut microbiota to precipitate spontaneous sex-biased central nervous system demyelinating autoimmune disease
    • Miller, P.G., M.B. Bonn, C.L. Franklin, et al. 2017. TNFR2 deficiency acts in concert with gut microbiota to precipitate spontaneous sex-biased central nervous system demyelinating autoimmune disease. J. Immunol. 195: 4668–4684.
    • (2017) J. Immunol. , vol.195 , pp. 4668-4684
    • Miller, P.G.1    Bonn, M.B.2    Franklin, C.L.3
  • 64
    • 85008932586 scopus 로고    scopus 로고
    • Correlation of gut microbiota composition with resistance to experimental autoimmune encephalomyelitis in rats
    • Stanisavljevic, S., J. Lukic, S. Sokivic, et al. 2016. Correlation of gut microbiota composition with resistance to experimental autoimmune encephalomyelitis in rats. Front. Microbiol. 7: 1–12.
    • (2016) Front. Microbiol. , vol.7 , pp. 1-12
    • Stanisavljevic, S.1    Lukic, J.2    Sokivic, S.3
  • 65
    • 85006192445 scopus 로고    scopus 로고
    • Dysbiosis of gut microbiota with reduced trimethylamine-n-oxide level in patients with large-artery atherosclerotic stroke or transient ischemic attack
    • Yin, J., S.-X. Liao, Y. He, S. Wang, et al. 2015. Dysbiosis of gut microbiota with reduced trimethylamine-n-oxide level in patients with large-artery atherosclerotic stroke or transient ischemic attack. J. Am. Heart Assoc. 4: 1–13.
    • (2015) J. Am. Heart Assoc. , vol.4 , pp. 1-13
    • Yin, J.1    Liao, S.-X.2    He, Y.3    Wang, S.4
  • 66
    • 85011695835 scopus 로고    scopus 로고
    • Gut dysbiosis is associated with metabolism and systemic inflammation in patients with ischemic stroke
    • Yamashiro, K., R. Tanaka, T. Urabe, et al. 2017. Gut dysbiosis is associated with metabolism and systemic inflammation in patients with ischemic stroke. PLoS One 12: e0171521.
    • (2017) PLoS One , vol.12
    • Yamashiro, K.1    Tanaka, R.2    Urabe, T.3
  • 67
    • 84964047906 scopus 로고    scopus 로고
    • Depletion of cultivatable gut microbiota by broad-spectrum antibiotic pretreatment worsens outcome after murine stroke
    • Winek, K., O. Engel, P. Koduah, et al. 2016. Depletion of cultivatable gut microbiota by broad-spectrum antibiotic pretreatment worsens outcome after murine stroke. Stroke 47: 1354–1363.
    • (2016) Stroke , vol.47 , pp. 1354-1363
    • Winek, K.1    Engel, O.2    Koduah, P.3
  • 68
    • 84978914875 scopus 로고    scopus 로고
    • Microbiota dysbiosis controls the neuroinflammatory response after stroke
    • Singh, V., S. Roth, G. Llovera, et al. 2016. Microbiota dysbiosis controls the neuroinflammatory response after stroke. J. Neurosci. 36: 7428–7440.
    • (2016) J. Neurosci. , vol.36 , pp. 7428-7440
    • Singh, V.1    Roth, S.2    Llovera, G.3
  • 69
    • 84989911375 scopus 로고    scopus 로고
    • Translocation and dissemination of commensal bacteria in post-stroke infection
    • Stanley, D., L.J. Mason, K.E. Mackin, et al. 2016. Translocation and dissemination of commensal bacteria in post-stroke infection. Nat. Med. 22: 1277–1284.
    • (2016) Nat. Med. , vol.22 , pp. 1277-1284
    • Stanley, D.1    Mason, L.J.2    Mackin, K.E.3
  • 70
    • 84959922537 scopus 로고    scopus 로고
    • Gut microbial metabolite TMAO enhances platelet article gut microbial metabolite TMAO enhances platelet hyperreactivity and thrombosis risk
    • Risk, T., W. Zhu, J.C. Gregory, et al. 2016. Gut microbial metabolite TMAO enhances platelet article gut microbial metabolite TMAO enhances platelet hyperreactivity and thrombosis risk. Cell 165: 111–124.
    • (2016) Cell , vol.165 , pp. 111-124
    • Risk, T.1    Zhu, W.2    Gregory, J.C.3
  • 71
    • 84950297830 scopus 로고    scopus 로고
    • Non-lethal inhibition of gut microbial trimethylamine production for the treatment of article non-lethal inhibition of gut microbial trimethylamine production for the treatment of atherosclerosis
    • Wang, Z., A.B. Roberts, J.A. Buffa, et al. 2015. Non-lethal inhibition of gut microbial trimethylamine production for the treatment of article non-lethal inhibition of gut microbial trimethylamine production for the treatment of atherosclerosis. Cell 163: 1585–1595.
    • (2015) Cell , vol.163 , pp. 1585-1595
    • Wang, Z.1    Roberts, A.B.2    Buffa, J.A.3
  • 72
    • 84961875569 scopus 로고    scopus 로고
    • Commensal microbiota affects ischemic stroke outcome by regulating intestinal γδ T cells
    • Benakis, C., D. Brea, S. Caballero, et al. 2016. Commensal microbiota affects ischemic stroke outcome by regulating intestinal γδ T cells. Nat. Med. 22: 516–523.
    • (2016) Nat. Med. , vol.22 , pp. 516-523
    • Benakis, C.1    Brea, D.2    Caballero, S.3
  • 73
    • 85016411650 scopus 로고    scopus 로고
    • Microbiota differences between commercial breeders impacts the post-stroke immune response
    • Sadler, R., V. Singh, C. Benakis, et al. 2017. Microbiota differences between commercial breeders impacts the post-stroke immune response. Brain Behav. Immun. https://doi.org/10.1016/j.bbi.2017.03.011.
    • (2017) Brain Behav. Immun.
    • Sadler, R.1    Singh, V.2    Benakis, C.3
  • 74
    • 84963699544 scopus 로고    scopus 로고
    • Brain injury induces specific changes in the caecal microbiota of mice via altered autonomic activity and mucoprotein production
    • Houlden, A., M. Goldrick, D. Brough, et al. 2016. Brain injury induces specific changes in the caecal microbiota of mice via altered autonomic activity and mucoprotein production. Brain Behav. Immun. 57: 10–20.
    • (2016) Brain Behav. Immun. , vol.57 , pp. 10-20
    • Houlden, A.1    Goldrick, M.2    Brough, D.3
  • 75
    • 84885209646 scopus 로고    scopus 로고
    • The effects of stress hormones on growth of selected periodontitis related bacteria
    • Jentsch, H.F.R., D. März & M. Krüger. 2013. The effects of stress hormones on growth of selected periodontitis related bacteria. Anaerobe 24: 49–54.
    • (2013) Anaerobe , vol.24 , pp. 49-54
    • Jentsch, H.F.R.1    März, D.2    Krüger, M.3
  • 76
    • 84999836790 scopus 로고    scopus 로고
    • Gut dysbiosis impairs recovery after spinal cord injury
    • Kigerl, K.A., J.C.E. Hall, L. Wang, et al. 2016. Gut dysbiosis impairs recovery after spinal cord injury. J. Exp. Med. 213: 2603–2620.
    • (2016) J. Exp. Med. , vol.213 , pp. 2603-2620
    • Kigerl, K.A.1    Hall, J.C.E.2    Wang, L.3
  • 77
    • 84963535734 scopus 로고    scopus 로고
    • Clostridium butyricum attenuates cerebral ischemia/reperfusion injury in diabetic mice via modulation of gut microbiota
    • Sun, J., F. Wang, Z. Ling, et al. 2016. Clostridium butyricum attenuates cerebral ischemia/reperfusion injury in diabetic mice via modulation of gut microbiota. Brain Res. 1642: 180–188.
    • (2016) Brain Res , vol.1642 , pp. 180-188
    • Sun, J.1    Wang, F.2    Ling, Z.3
  • 78
    • 84929150186 scopus 로고    scopus 로고
    • Psychobiotics and the gut–brain axis: in the pursuit of happiness
    • Zhou, L. & J.A. Foster. 2015. Psychobiotics and the gut–brain axis: in the pursuit of happiness. Neuropsychiatr. Dis. Treat. 11: 715–723.
    • (2015) Neuropsychiatr. Dis. Treat. , vol.11 , pp. 715-723
    • Zhou, L.1    Foster, J.A.2
  • 79
    • 85013115760 scopus 로고    scopus 로고
    • Variations in gut microbiota and fecal metabolic phenotype associated with depression by 16S rRNA gene sequencing and LC/MS-based metabolomics
    • Yu, M., H. Jia, C. Zhou, et al. 2017. Variations in gut microbiota and fecal metabolic phenotype associated with depression by 16S rRNA gene sequencing and LC/MS-based metabolomics. J. Pharm. Biomed. Anal. 138: 231–239.
    • (2017) J. Pharm. Biomed. Anal. , vol.138 , pp. 231-239
    • Yu, M.1    Jia, H.2    Zhou, C.3
  • 80
    • 84979955472 scopus 로고    scopus 로고
    • Transferring the blues: depression-associated gut microbiota induces neurobehavioural changes in the rat
    • Kelly, J.R., Y. Borre, C. O’ Brien, et al. 2016. Transferring the blues: depression-associated gut microbiota induces neurobehavioural changes in the rat. J. Psychiatr Res. 82: 109–118.
    • (2016) J. Psychiatr Res. , vol.82 , pp. 109-118
    • Kelly, J.R.1    Borre, Y.2    O’ Brien, C.3
  • 81
    • 84963547235 scopus 로고    scopus 로고
    • Gut microbiome remodeling induces depressive-like behaviors through a pathway mediated by the host's metabolism
    • Zheng, P., B. Zeng, C. Zhou, et al. 2016. Gut microbiome remodeling induces depressive-like behaviors through a pathway mediated by the host's metabolism. Mol. Psychiatry 21:786–796.
    • (2016) Mol. Psychiatry , vol.21 , pp. 786-796
    • Zheng, P.1    Zeng, B.2    Zhou, C.3
  • 82
    • 85014649400 scopus 로고    scopus 로고
    • Transplantation of fecal microbiota from patients with irritable bowel syndrome alters gut function and behavior in recipient mice
    • De Palma, G., M.D.J. Lynch, J. Lu, et al. 2017. Transplantation of fecal microbiota from patients with irritable bowel syndrome alters gut function and behavior in recipient mice. Sci. Transl. Med. 6397: 1–15.
    • (2017) Sci. Transl. Med. , vol.6397 , pp. 1-15
    • De Palma, G.1    Lynch, M.D.J.2    Lu, J.3
  • 83
    • 85013756511 scopus 로고    scopus 로고
    • Targeting the microbiota–gut–brain axis: prebiotics have anxiolytic and antidepressant-like effects and reverse the impact of chronic stress in mice
    • Burokas, A., S. Arboleya, D. Rachel, et al. 2017. Targeting the microbiota–gut–brain axis: prebiotics have anxiolytic and antidepressant-like effects and reverse the impact of chronic stress in mice. Biol. Psychiatry. https://doi.org/10.1016/j.biopsych.2016.12.031.
    • (2017) Biol. Psychiatry.
    • Burokas, A.1    Arboleya, S.2    Rachel, D.3
  • 84
    • 84953369399 scopus 로고    scopus 로고
    • Prebiotic administration normalizes lipopolysaccharide (LPS)-induced anxiety and cortical 5-HT2A receptor and IL1 levels in male mice
    • Savignac, H.M., Y. Couch, M. Stratford, et al. 2016. Prebiotic administration normalizes lipopolysaccharide (LPS)-induced anxiety and cortical 5-HT2A receptor and IL1 levels in male mice. Brain Behav. Immun. 52: 120–131.
    • (2016) Brain Behav. Immun. , vol.52 , pp. 120-131
    • Savignac, H.M.1    Couch, Y.2    Stratford, M.3
  • 85
    • 84936803964 scopus 로고    scopus 로고
    • The prebiotics 3′sialyllactose and 6′sialyllactose diminish stressor-induced anxiety-like behavior and colonic microbiota alterations: evidence for effects on the gut–brain axis
    • Tarr, A.J., J.D. Galley, S.E. Fisher, et al. 2015. The prebiotics 3′sialyllactose and 6′sialyllactose diminish stressor-induced anxiety-like behavior and colonic microbiota alterations: evidence for effects on the gut–brain axis. Brain Behav. Immun. 50: 166–177.
    • (2015) Brain Behav. Immun. , vol.50 , pp. 166-177
    • Tarr, A.J.1    Galley, J.D.2    Fisher, S.E.3
  • 86
    • 84937636483 scopus 로고    scopus 로고
    • Prebiotic intake reduces the waking cortisol response and alters emotional bias in healthy volunteers
    • Schmidt, K., P.J. Cowen, C.J. Harmer, et al. 2015. Prebiotic intake reduces the waking cortisol response and alters emotional bias in healthy volunteers. Psychopharmacology (Berl.) 232: 1793–1801.
    • (2015) Psychopharmacology (Berl.) , vol.232 , pp. 1793-1801
    • Schmidt, K.1    Cowen, P.J.2    Harmer, C.J.3
  • 87
    • 85008675464 scopus 로고    scopus 로고
    • Oral treatment with Lactobacillus rhamnosus attenuates behavioural deficits and immune changes in chronic social stress
    • Bharwani, A., M.F. Mian, M.G. Surette, et al. 2017. Oral treatment with Lactobacillus rhamnosus attenuates behavioural deficits and immune changes in chronic social stress. BMC Med. 15: 7.
    • (2017) BMC Med , vol.15 , pp. 7
    • Bharwani, A.1    Mian, M.F.2    Surette, M.G.3
  • 88
    • 80052965474 scopus 로고    scopus 로고
    • Ingestion of Lactobacillus strain regulates emotional behavior and central GABA receptor expression in a mouse via the vagus nerve
    • Bravo, J.A., P. Forsythe, M.V. Chew, et al. 2011. Ingestion of Lactobacillus strain regulates emotional behavior and central GABA receptor expression in a mouse via the vagus nerve. Proc. Natl. Acad. Sci. U.S.A. 108: 16050–16055.
    • (2011) Proc. Natl. Acad. Sci. U.S.A. , vol.108 , pp. 16050-16055
    • Bravo, J.A.1    Forsythe, P.2    Chew, M.V.3
  • 89
    • 85007233429 scopus 로고    scopus 로고
    • Lost in translation? The potential psychobiotic Lactobacillus rhamnosus (JB-1) fails to modulate stress or cognitive performance in healthy male subjects
    • Kelly, J.R., A.P. Allen, A. Temko, et al. 2017. Lost in translation? The potential psychobiotic Lactobacillus rhamnosus (JB-1) fails to modulate stress or cognitive performance in healthy male subjects. Brain Behav. Immun. 61: 50–59.
    • (2017) Brain Behav. Immun , vol.61 , pp. 50-59
    • Kelly, J.R.1    Allen, A.P.2    Temko, A.3
  • 90
    • 84994275309 scopus 로고    scopus 로고
    • Bifidobacterium longum 1714 as a translational psychobiotic: modulation of stress, electrophysiology and neurocognition in healthy volunteers
    • Allen, A.P., W. Hutch, Y.E. Borre, et al. 2016. Bifidobacterium longum 1714 as a translational psychobiotic: modulation of stress, electrophysiology and neurocognition in healthy volunteers. Transl. Psychiatry 6: e939.
    • (2016) Transl. Psychiatry , vol.6
    • Allen, A.P.1    Hutch, W.2    Borre, Y.E.3
  • 91
    • 84878287270 scopus 로고    scopus 로고
    • Consumption of fermented milk product with probiotic modulates brain activity
    • 1401.e1-4
    • Tillisch, K., J. Labus, L. Kilpatrick, et al. 2013. Consumption of fermented milk product with probiotic modulates brain activity. Gastroenterology 144: 1394–1401, 1401.e1-4.
    • (2013) Gastroenterology , vol.144 , pp. 1394-1401
    • Tillisch, K.1    Labus, J.2    Kilpatrick, L.3
  • 92
    • 85021338194 scopus 로고    scopus 로고
    • Probiotic Bifidobacterium longum NCC3001 reduces depression scores and alters brain activity: a pilot study in patients with irritable bowel syndrome
    • Pinto-sanchez, M.I., G.B. Hall, K. Ghajar, et al. 2017. Probiotic Bifidobacterium longum NCC3001 reduces depression scores and alters brain activity: a pilot study in patients with irritable bowel syndrome. Gastroenterology https://doi.org/10.1053/j.gastro.2017.05.003.
    • (2017) Gastroenterology
    • Pinto-sanchez, M.I.1    Hall, G.B.2    Ghajar, K.3
  • 93
    • 84920931626 scopus 로고    scopus 로고
    • Fecal microbiota transplantation broadening its application beyond intestinal disorders
    • Xu, M., H. Cao, W. Wang, et al. 2015. Fecal microbiota transplantation broadening its application beyond intestinal disorders. World J. Gastroenterol. 21: 102–111.
    • (2015) World J. Gastroenterol. , vol.21 , pp. 102-111
    • Xu, M.1    Cao, H.2    Wang, W.3
  • 94
    • 84988448914 scopus 로고    scopus 로고
    • Fecal microbiota transplantation and its usage in neuropsychiatric disorders
    • Evrensel, A. & M.E. Ceylan. 2016. Fecal microbiota transplantation and its usage in neuropsychiatric disorders. Clin. Psychopharmacol. Neurosci. 14: 231–237.
    • (2016) Clin. Psychopharmacol. Neurosci. , vol.14 , pp. 231-237
    • Evrensel, A.1    Ceylan, M.E.2
  • 95
    • 84938379194 scopus 로고    scopus 로고
    • Neuropeptides and the microbiota–gut–brain axis
    • Holzer, P. & A. Farzi. 2014. Neuropeptides and the microbiota–gut–brain axis. Adv. Exp. Med. Biol. 817: 39–71.
    • (2014) Adv. Exp. Med. Biol. , vol.817 , pp. 39-71
    • Holzer, P.1    Farzi, A.2
  • 96
    • 84994802519 scopus 로고    scopus 로고
    • Neuropeptides, microbiota, and behavior
    • Holzer, P. 2016. Neuropeptides, microbiota, and behavior. Int. Rev. Neurobiol. 131: 67–89.
    • (2016) Int. Rev. Neurobiol. , vol.131 , pp. 67-89
    • Holzer, P.1
  • 97
    • 84975317355 scopus 로고    scopus 로고
    • Microbial reconstitution reverses maternal diet-induced social and synaptic deficits in offspring
    • Buffington, S.A., G.V. Di Prisco, T.A. Auchtung, et al. 2016. Microbial reconstitution reverses maternal diet-induced social and synaptic deficits in offspring. Cell 165: 1762–1775.
    • (2016) Cell , vol.165 , pp. 1762-1775
    • Buffington, S.A.1    Di Prisco, G.V.2    Auchtung, T.A.3
  • 98
    • 84893696250 scopus 로고    scopus 로고
    • Microbiota is essential for social development in the mouse
    • Desbonnet, L., G. Clarke, F. Shanahan, et al. 2014. Microbiota is essential for social development in the mouse. Mol. Psychiatry 19: 146–148.
    • (2014) Mol. Psychiatry , vol.19 , pp. 146-148
    • Desbonnet, L.1    Clarke, G.2    Shanahan, F.3
  • 99
    • 84938273954 scopus 로고    scopus 로고
    • Gut microbiota depletion from early adolescence in mice: implications for brain and behaviour
    • Desbonnet, L., G. Clarke, A. Traplin, et al. 2015. Gut microbiota depletion from early adolescence in mice: implications for brain and behaviour. Brain Behav. Immun. 48: 165–173.
    • (2015) Brain Behav. Immun. , vol.48 , pp. 165-173
    • Desbonnet, L.1    Clarke, G.2    Traplin, A.3
  • 100
    • 84971253961 scopus 로고    scopus 로고
    • Host microbiota modulates development of social preference in mice
    • Arentsen, T., H. Raith, Y. Qian, et al. 2015. Host microbiota modulates development of social preference in mice. Microb. Ecol. Health Dis. 26: 29719.
    • (2015) Microb. Ecol. Health Dis. , vol.26 , pp. 29719
    • Arentsen, T.1    Raith, H.2    Qian, Y.3
  • 101
    • 84896728399 scopus 로고    scopus 로고
    • Altered gut microbiota and activity in a murine model of autism spectrum disorders
    • de Theije, C.G.M., H. Wopereis, M. Ramadan, et al. 2014. Altered gut microbiota and activity in a murine model of autism spectrum disorders. Brain Behav. Immun. 37: 197–206.
    • (2014) Brain Behav. Immun. , vol.37 , pp. 197-206
    • de Theije, C.G.M.1    Wopereis, H.2    Ramadan, M.3
  • 102
    • 84896734080 scopus 로고    scopus 로고
    • Intestinal inflammation in a murine model of autism spectrum disorders
    • de Theije, C.G., P.J. Koelink, G.A. Korte-Bouws, et al. 2014. Intestinal inflammation in a murine model of autism spectrum disorders. Brain Behav. Immun. 37: 240–247.
    • (2014) Brain Behav. Immun. , vol.37 , pp. 240-247
    • de Theije, C.G.1    Koelink, P.J.2    Korte-Bouws, G.A.3
  • 103
    • 84894118144 scopus 로고    scopus 로고
    • Microbiota modulate behavioral and physiological abnormalities associated with neurodevelopmental disorders
    • Hsiao, E.Y., S.W. McBride, S. Hsien, et al. 2013. Microbiota modulate behavioral and physiological abnormalities associated with neurodevelopmental disorders. Cell 155: 1451–1463.
    • (2013) Cell , vol.155 , pp. 1451-1463
    • Hsiao, E.Y.1    McBride, S.W.2    Hsien, S.3
  • 104
    • 40349093351 scopus 로고    scopus 로고
    • Autism-like behavioral phenotypes in BTBR T+tf/J mice
    • McFarlane, H.G., G.K. Kusek, M. Yang, et al. 2008. Autism-like behavioral phenotypes in BTBR T+tf/J mice. Genes Brain Behav. 7: 152–163.
    • (2008) Genes Brain Behav , vol.7 , pp. 152-163
    • McFarlane, H.G.1    Kusek, G.K.2    Yang, M.3
  • 105
    • 84952895502 scopus 로고    scopus 로고
    • Evaluation of the neuroactive steroid ganaxolone on social and repetitive behaviors in the BTBR mouse model of autism
    • Kazdoba, T.M., R.J. Hagerman, D. Zolkowska, et al. 2015. Evaluation of the neuroactive steroid ganaxolone on social and repetitive behaviors in the BTBR mouse model of autism. Psychopharmacology (Berl.) 233: 309–323.
    • (2015) Psychopharmacology (Berl.) , vol.233 , pp. 309-323
    • Kazdoba, T.M.1    Hagerman, R.J.2    Zolkowska, D.3
  • 106
    • 84947918250 scopus 로고    scopus 로고
    • Sodium butyrate attenuates social behavior deficits and modifies the transcription of inhibitory/excitatory genes in the frontal cortex of an autism model
    • Kratsman, N., D. Getselter & E. Elliott. 2016. Sodium butyrate attenuates social behavior deficits and modifies the transcription of inhibitory/excitatory genes in the frontal cortex of an autism model. Neuropharmacology 102: 136–145.
    • (2016) Neuropharmacology , vol.102 , pp. 136-145
    • Kratsman, N.1    Getselter, D.2    Elliott, E.3
  • 107
    • 84987629405 scopus 로고    scopus 로고
    • Ketogenic diet modifies the gut microbiota in a murine model of autism spectrum disorder
    • Newell, C., M.R. Bomhof, R.A. Reimer, et al. 2016. Ketogenic diet modifies the gut microbiota in a murine model of autism spectrum disorder. Mol. Autism 7: 37.
    • (2016) Mol. Autism , vol.7 , pp. 37
    • Newell, C.1    Bomhof, M.R.2    Reimer, R.A.3
  • 108
    • 85016009015 scopus 로고    scopus 로고
    • Microbiota transfer therapy alters gut ecosystem and improves gastrointestinal and autism symptoms: an open-label study
    • Kang, D.-W., J.B. Adams, A.C. Gregory, et al. 2017. Microbiota transfer therapy alters gut ecosystem and improves gastrointestinal and autism symptoms: an open-label study. Microbiome 5: 10.
    • (2017) Microbiome , vol.5 , pp. 10
    • Kang, D.-W.1    Adams, J.B.2    Gregory, A.C.3
  • 109
    • 84962890386 scopus 로고    scopus 로고
    • Advancing the understanding of autism disease mechanisms through genetics
    • De La Torre-Ubieta, L., H. Won, J.L. Stein & D.H. Geschwind. 2016. Advancing the understanding of autism disease mechanisms through genetics. Nat. Med. 22: 345–361.
    • (2016) Nat. Med. , vol.22 , pp. 345-361
    • De La Torre-Ubieta, L.1    Won, H.2    Stein, J.L.3    Geschwind, D.H.4
  • 110
    • 84894588779 scopus 로고    scopus 로고
    • Toward effective probiotics for autism and other neurodevelopmental disorders
    • Gilbert, J.A., R. Krajmalnik-Brown, D.L. Porazinska, et al. 2013. Toward effective probiotics for autism and other neurodevelopmental disorders. Cell 155: 1446–1448.
    • (2013) Cell , vol.155 , pp. 1446-1448
    • Gilbert, J.A.1    Krajmalnik-Brown, R.2    Porazinska, D.L.3
  • 112
  • 113
    • 84885135911 scopus 로고    scopus 로고
    • Antipsychotics and the gut microbiome: olanzapine-induced metabolic dysfunction is attenuated by antibiotic administration in the rat
    • Davey, K.J., P.D. Cotter, O. O'Sullivan, et al. 2013. Antipsychotics and the gut microbiome: olanzapine-induced metabolic dysfunction is attenuated by antibiotic administration in the rat. Transl. Psychiatry 3: e309.
    • (2013) Transl. Psychiatry , vol.3
    • Davey, K.J.1    Cotter, P.D.2    O'Sullivan, O.3
  • 114
    • 84954287816 scopus 로고    scopus 로고
    • Intestinal microbiota contributes to individual susceptibility to alcoholic liver disease
    • Llopis, M., A.M. Cassard, L. Wrzosek, et al. 2016. Intestinal microbiota contributes to individual susceptibility to alcoholic liver disease. Gut 65: 830–839.
    • (2016) Gut , vol.65 , pp. 830-839
    • Llopis, M.1    Cassard, A.M.2    Wrzosek, L.3
  • 115
    • 85011957202 scopus 로고    scopus 로고
    • Drunk bugs: chronic vapour alcohol exposure induces marked changes in the gut microbiome in mice
    • Peterson, V.L., N.J. Jury, R. Cabrera-Rubio, et al. 2017. Drunk bugs: chronic vapour alcohol exposure induces marked changes in the gut microbiome in mice. Behav. Brain Res. 323: 172–176.
    • (2017) Behav. Brain Res. , vol.323 , pp. 172-176
    • Peterson, V.L.1    Jury, N.J.2    Cabrera-Rubio, R.3
  • 116
    • 84974783042 scopus 로고    scopus 로고
    • Ecophysiological consequences of alcoholism on human gut microbiota: implications for ethanol-related pathogenesis of colon cancer
    • Tsuruya, A., A. Kuwahara, Y. Saito, et al. 2016. Ecophysiological consequences of alcoholism on human gut microbiota: implications for ethanol-related pathogenesis of colon cancer. Sci. Rep. 6: 27923.
    • (2016) Sci. Rep. , vol.6 , pp. 27923
    • Tsuruya, A.1    Kuwahara, A.2    Saito, Y.3
  • 117
    • 84908043065 scopus 로고    scopus 로고
    • Intestinal permeability, gut–bacterial dysbiosis, and behavioral markers of alcohol-dependence severity
    • Leclercq, S., S. Matamoros, P.D. Cani, et al. 2014. Intestinal permeability, gut–bacterial dysbiosis, and behavioral markers of alcohol-dependence severity. Proc. Natl. Acad. Sci. U.S.A. 111: E4485–E4493.
    • (2014) Proc. Natl. Acad. Sci. U.S.A. , vol.111 , pp. E4485-E4493
    • Leclercq, S.1    Matamoros, S.2    Cani, P.D.3
  • 118
    • 55949124035 scopus 로고    scopus 로고
    • Faecalibacterium prausnitzii is an anti-inflammatory commensal bacterium identified by gut microbiota analysis of Crohn disease patients
    • Sokol, H., B. Pigneur, L. Watterlot, et al. 2008. Faecalibacterium prausnitzii is an anti-inflammatory commensal bacterium identified by gut microbiota analysis of Crohn disease patients. Proc. Natl. Acad. Sci. U.S.A. 105: 16731–16736.
    • (2008) Proc. Natl. Acad. Sci. U.S.A. , vol.105 , pp. 16731-16736
    • Sokol, H.1    Pigneur, B.2    Watterlot, L.3
  • 119
    • 84863436944 scopus 로고    scopus 로고
    • Dietary-fat-induced taurocholic acid promotes pathobiont expansion and colitis in Il10–/– mice
    • Devkota, S., Y. Wang, M.W. Musch, et al. 2012. Dietary-fat-induced taurocholic acid promotes pathobiont expansion and colitis in Il10–/– mice. Nature 487: 104–108.
    • (2012) Nature , vol.487 , pp. 104-108
    • Devkota, S.1    Wang, Y.2    Musch, M.W.3
  • 120
    • 84992345480 scopus 로고    scopus 로고
    • Alterations of the host microbiome affect behavioral responses to cocaine
    • Kiraly, D.D., D.M. Walker, E.S. Calipari, et al. 2016. Alterations of the host microbiome affect behavioral responses to cocaine. Sci. Rep. 6: 35455.
    • (2016) Sci. Rep. , vol.6 , pp. 35455
    • Kiraly, D.D.1    Walker, D.M.2    Calipari, E.S.3
  • 121
    • 84955481668 scopus 로고    scopus 로고
    • Prevention of diet-induced obesity effects on body weight and gut microbiota in mice treated chronically with δ9-tetrahydrocannabinol
    • Cluny, N.L., C.M. Keenan, R.A. Reimer, et al. 2015. Prevention of diet-induced obesity effects on body weight and gut microbiota in mice treated chronically with δ9-tetrahydrocannabinol. PLoS One 10: e0144270.
    • (2015) PLoS One , vol.10
    • Cluny, N.L.1    Keenan, C.M.2    Reimer, R.A.3
  • 122
    • 84997701899 scopus 로고    scopus 로고
    • A purified membrane protein from Akkermansia muciniphila or the pasteurized bacterium improves metabolism in obese and diabetic mice
    • Plovier, H., A. Everard, C. Druart, et al. 2017. A purified membrane protein from Akkermansia muciniphila or the pasteurized bacterium improves metabolism in obese and diabetic mice. Nat. Med. 23: 107–113.
    • (2017) Nat. Med. , vol.23 , pp. 107-113
    • Plovier, H.1    Everard, A.2    Druart, C.3
  • 123
    • 84954099831 scopus 로고    scopus 로고
    • Diet-induced extinctions in the gut microbiota compound over generations
    • Sonnenburg, E.D., S.A. Smits, M. Tikhonov, et al. 2016. Diet-induced extinctions in the gut microbiota compound over generations. Nature 529: 212–215.
    • (2016) Nature , vol.529 , pp. 212-215
    • Sonnenburg, E.D.1    Smits, S.A.2    Tikhonov, M.3
  • 124
    • 84987767263 scopus 로고    scopus 로고
    • Fecal metabolome of the Hadza hunter-gatherers: a host–microbiome integrative view
    • Turroni, S., J. Fiori, S. Rampelli, et al. 2016. Fecal metabolome of the Hadza hunter-gatherers: a host–microbiome integrative view. Sci. Rep. 6: 32826.
    • (2016) Sci. Rep. , vol.6 , pp. 32826
    • Turroni, S.1    Fiori, J.2    Rampelli, S.3
  • 125
    • 84905678546 scopus 로고    scopus 로고
    • Food and nutrient intake of Irish community-dwelling elderly subjects: who is at nutritional risk?
    • Power, S.E., I.B. Jeffery, R.P. Ross, et al. 2014. Food and nutrient intake of Irish community-dwelling elderly subjects: who is at nutritional risk? J. Nutr. Health Aging 18: 561–572.
    • (2014) J. Nutr. Health Aging , vol.18 , pp. 561-572
    • Power, S.E.1    Jeffery, I.B.2    Ross, R.P.3
  • 126
    • 85006096898 scopus 로고    scopus 로고
    • Feeding the microbiota–gut–brain axis: diet, microbiome and neuropsychiatry
    • Sandhu K.V., E. Sherwin, H. Schellekens, et al. 2016. Feeding the microbiota–gut–brain axis: diet, microbiome and neuropsychiatry. Transl. Res. 179: 223–244.
    • (2016) Transl. Res. , vol.179 , pp. 223-244
    • Sandhu, K.V.1    Sherwin, E.2    Schellekens, H.3
  • 127
    • 84997785101 scopus 로고    scopus 로고
    • Omega-3 polyunsaturated fatty acids critically regulate behaviour and gut microbiota development in adolescence and adulthood
    • Robertson, R.C., C. Seira Oriach, K. Murphy, et al. 2016. Omega-3 polyunsaturated fatty acids critically regulate behaviour and gut microbiota development in adolescence and adulthood. Brain Behav. Immun. 59: 21–37
    • (2016) Brain Behav. Immun. , vol.59 , pp. 21-37
    • Robertson, R.C.1    Seira Oriach, C.2    Murphy, K.3
  • 128
    • 84930193348 scopus 로고    scopus 로고
    • n-3 PUFAs have beneficial effects on anxiety and cognition in female rats: effects of early life stress
    • Pusceddu, M.M., P. Kelly, N. Ariffin, et al. 2015. n-3 PUFAs have beneficial effects on anxiety and cognition in female rats: effects of early life stress. Psychoneuroendocrinology 58: 79–90.
    • (2015) Psychoneuroendocrinology , vol.58 , pp. 79-90
    • Pusceddu, M.M.1    Kelly, P.2    Ariffin, N.3
  • 130
    • 84878767710 scopus 로고    scopus 로고
    • Ketogenic diet improves core symptoms of autism in BTBR mice
    • Ruskin, D.N., J. Svedova, J.L. Cote, et al. 2013. Ketogenic diet improves core symptoms of autism in BTBR mice. PLoS One 8: 4–9.
    • (2013) PLoS One , vol.8 , pp. 4-9
    • Ruskin, D.N.1    Svedova, J.2    Cote, J.L.3
  • 131
    • 85011632713 scopus 로고    scopus 로고
    • Ketogenic diet improves behaviors in a maternal immune activation model of autism spectrum disorder
    • Ruskin, D.N., M.I. Murphy, S.L. Slade & S.A. Masino. 2017. Ketogenic diet improves behaviors in a maternal immune activation model of autism spectrum disorder. PLos One 12: e0171643.
    • (2017) PLos One , vol.12
    • Ruskin, D.N.1    Murphy, M.I.2    Slade, S.L.3    Masino, S.A.4
  • 132
    • 85020637493 scopus 로고    scopus 로고
    • The effect of ketogenic diet in an animal model of autism induced by prenatal exposure to valproic acid
    • Castro, K., D. Baronio, I.S. Perry, et al. 2016. The effect of ketogenic diet in an animal model of autism induced by prenatal exposure to valproic acid. Nutr. Neurosci. 9: 1–8.
    • (2016) Nutr. Neurosci. , vol.9 , pp. 1-8
    • Castro, K.1    Baronio, D.2    Perry, I.S.3
  • 133
    • 85000351103 scopus 로고    scopus 로고
    • Dietary interventions that reduce mTOR activity rescue autistic-like behavioral deficits in mice
    • Wu, J., C.G.M. de Theije, S.L. da Silva, et al. 2016. Dietary interventions that reduce mTOR activity rescue autistic-like behavioral deficits in mice. Brain Behav. Immun. 59: 273–287.
    • (2016) Brain Behav. Immun. , vol.59 , pp. 273-287
    • Wu, J.1    de Theije, C.G.M.2    da Silva, S.L.3
  • 134
    • 84973665415 scopus 로고    scopus 로고
    • Effect of gluten free diet on gastrointestinal and behavioral indices for children with autism spectrum disorders: a randomized clinical trial
    • Ghalichi, F., J. Ghaemmaghami, A. Malek & A. Ostadrahimi. 2016. Effect of gluten free diet on gastrointestinal and behavioral indices for children with autism spectrum disorders: a randomized clinical trial. World J. Pediatr. 12: 436–442.
    • (2016) World J. Pediatr. , vol.12 , pp. 436-442
    • Ghalichi, F.1    Ghaemmaghami, J.2    Malek, A.3    Ostadrahimi, A.4
  • 136
    • 84995495735 scopus 로고    scopus 로고
    • The bacterial peptidoglycan-sensing molecule Pglyrp2 modulates brain development and behavior
    • Arentsen, T., Y. Qian, S. Gkotzis, et al. 2017. The bacterial peptidoglycan-sensing molecule Pglyrp2 modulates brain development and behavior. Mol. Psychiatry 22: 257–266.
    • (2017) Mol. Psychiatry , vol.22 , pp. 257-266
    • Arentsen, T.1    Qian, Y.2    Gkotzis, S.3
  • 137
    • 84938503724 scopus 로고    scopus 로고
    • Probiotics improve inflammation-associated sickness behavior by altering communication between the peripheral immune system and the brain
    • D'Mello, C., N. Ronaghan, R. Zaheer, et al. 2015. Probiotics improve inflammation-associated sickness behavior by altering communication between the peripheral immune system and the brain. J. Neurosci. 35: 10821–10830.
    • (2015) J. Neurosci. , vol.35 , pp. 10821-10830
    • D'Mello, C.1    Ronaghan, N.2    Zaheer, R.3
  • 138
    • 81855194317 scopus 로고    scopus 로고
    • The anxiolytic effect of Bifidobacterium longum NCC3001 involves vagal pathways for gut–brain communication
    • Bercik, P., A.J. Park, D. Sinclair, et al. 2011. The anxiolytic effect of Bifidobacterium longum NCC3001 involves vagal pathways for gut–brain communication. Neurogastroenterol. Motil. 23: 1132–1139.
    • (2011) Neurogastroenterol. Motil. , vol.23 , pp. 1132-1139
    • Bercik, P.1    Park, A.J.2    Sinclair, D.3
  • 139
    • 84894235009 scopus 로고    scopus 로고
    • Microbial symbionts accelerate wound healing via the neuropeptide hormone oxytocin
    • Poutahidis, T., S.M. Kearney, T. Levkovich, et al. 2013. Microbial symbionts accelerate wound healing via the neuropeptide hormone oxytocin. PLoS One 8: e78898.
    • (2013) PLoS One , vol.8
    • Poutahidis, T.1    Kearney, S.M.2    Levkovich, T.3
  • 141
    • 85011283190 scopus 로고    scopus 로고
    • Microbial endocrinology in the pathogenesis of infectious disease
    • Lyte, M. 2016. Microbial endocrinology in the pathogenesis of infectious disease. Microbiol. Spectr. 4.
    • (2016) Microbiol. Spectr , vol.4
    • Lyte, M.1
  • 142
    • 84927131694 scopus 로고    scopus 로고
    • Indigenous bacteria from the gut microbiota regulate host serotonin biosynthesis
    • Yano, J.M., K. Yu, G.P. Donaldson, et al. 2015. Indigenous bacteria from the gut microbiota regulate host serotonin biosynthesis. Cell 161: 264–276.
    • (2015) Cell , vol.161 , pp. 264-276
    • Yano, J.M.1    Yu, K.2    Donaldson, G.P.3
  • 143
    • 84878241830 scopus 로고    scopus 로고
    • The microbiome–gut–brain axis during early life regulates the hippocampal serotonergic system in a sex-dependent manner
    • Clarke, G., S. Grenham, P. Scully, et al. 2013. The microbiome–gut–brain axis during early life regulates the hippocampal serotonergic system in a sex-dependent manner. Mol. Psychiatry 18: 666–673.
    • (2013) Mol. Psychiatry , vol.18 , pp. 666-673
    • Clarke, G.1    Grenham, S.2    Scully, P.3
  • 144
    • 84957965849 scopus 로고    scopus 로고
    • Gut commensal E. coli proteins activate host satiety pathways following nutrient-induced bacterial growth
    • Breton, J., N. Tennoune, N. Lucas, et al. 2016. Gut commensal E. coli proteins activate host satiety pathways following nutrient-induced bacterial growth. Cell Metab. 23: 1–11.
    • (2016) Cell Metab. , vol.23 , pp. 1-11
    • Breton, J.1    Tennoune, N.2    Lucas, N.3
  • 145
    • 84991467073 scopus 로고    scopus 로고
    • Bacterial ClpB heat-shock protein, an antigen-mimetic of the anorexigenic peptide α-MSH, at the origin of eating disorders
    • Tennoune, N., P. Chan, J. Breton, et al. 2014. Bacterial ClpB heat-shock protein, an antigen-mimetic of the anorexigenic peptide α-MSH, at the origin of eating disorders. Transl. Psychiatry 4: e458.
    • (2014) Transl. Psychiatry , vol.4
    • Tennoune, N.1    Chan, P.2    Breton, J.3
  • 146
    • 84919703596 scopus 로고    scopus 로고
    • The melanocortin-4 receptor is expressed in enteroendocrine l cells and regulates the release of peptide YY and glucagon-like peptide 1 in vivo
    • Panaro, B.L., I.R. Tough, M.S. Engelstoft, et al. 2014. The melanocortin-4 receptor is expressed in enteroendocrine l cells and regulates the release of peptide YY and glucagon-like peptide 1 in vivo. Cell Metab. 20: 1018–1029.
    • (2014) Cell Metab , vol.20 , pp. 1018-1029
    • Panaro, B.L.1    Tough, I.R.2    Engelstoft, M.S.3
  • 147
    • 84982952601 scopus 로고    scopus 로고
    • Elevated plasma concentrations of bacterial ClpB protein in patients with eating disorders
    • Breton, J., R. Legrand, K. Akkermann, et al. 2016. Elevated plasma concentrations of bacterial ClpB protein in patients with eating disorders. Int. J. Eat Disord. 49: 805–808.
    • (2016) Int. J. Eat Disord. , vol.49 , pp. 805-808
    • Breton, J.1    Legrand, R.2    Akkermann, K.3
  • 148
    • 84872686051 scopus 로고    scopus 로고
    • The microbiome is essential for normal gut intrinsic primary afferent neuron excitability in the mouse
    • Mcvey Neufeld, K.A., Y.K. Mao, J. Bienenstock, et al. 2013. The microbiome is essential for normal gut intrinsic primary afferent neuron excitability in the mouse. Neurogastroenterol. Motil. 25: 183–190.
    • (2013) Neurogastroenterol. Motil. , vol.25 , pp. 183-190
    • Mcvey Neufeld, K.A.1    Mao, Y.K.2    Bienenstock, J.3
  • 149
    • 84928211169 scopus 로고    scopus 로고
    • The gut microbiome restores intrinsic and extrinsic nerve function in germ-free mice accompanied by changes in calbindin
    • Mcvey Neufeld, K.A., A. Perez-Burgos, Y.K. Mao, et al. 2015. The gut microbiome restores intrinsic and extrinsic nerve function in germ-free mice accompanied by changes in calbindin. Neurogastroenterol. Motil. 27: 627–636.
    • (2015) Neurogastroenterol. Motil. , vol.27 , pp. 627-636
    • Mcvey Neufeld, K.A.1    Perez-Burgos, A.2    Mao, Y.K.3
  • 150
    • 84989157896 scopus 로고    scopus 로고
    • Growing up in a bubble: using germ-free animals to assess the influence of the gut microbiota on brain and behavior
    • Luczynski, P., K.A.M.V. Neufeld, C.S. Oriach, et al. 2016. Growing up in a bubble: using germ-free animals to assess the influence of the gut microbiota on brain and behavior. Int. J. Neuropsychopharmacol. 19: 1–17.
    • (2016) Int. J. Neuropsychopharmacol. , vol.19 , pp. 1-17
    • Luczynski, P.1    Neufeld, K.A.M.V.2    Oriach, C.S.3
  • 151
    • 72449160264 scopus 로고    scopus 로고
    • Lactobacillus reuteri ingestion and IKCa channel blockade have similar effects on rat colon motility and myenteric neurones
    • Wang, B., Y.K. Mao, C. Diorio, et al. 2009. Lactobacillus reuteri ingestion and IKCa channel blockade have similar effects on rat colon motility and myenteric neurones. Neurogastroenterol. Motil. 22: 98–e33.
    • (2009) Neurogastroenterol. Motil. , vol.22 , pp. 33-98
    • Wang, B.1    Mao, Y.K.2    Diorio, C.3
  • 152
    • 84874019206 scopus 로고    scopus 로고
    • Spatiotemporal maps reveal regional differences in the effects on gut motility for Lactobacillus reuteri and rhamnosus strains
    • Wu, R.Y., M. Pasyk, B. Wang, et al. 2013. Spatiotemporal maps reveal regional differences in the effects on gut motility for Lactobacillus reuteri and rhamnosus strains. Neurogastroenterol. Motil. 25: e205–1.
    • (2013) Neurogastroenterol. Motil. , vol.25 , pp. 201-205
    • Wu, R.Y.1    Pasyk, M.2    Wang, B.3
  • 153
    • 84874622244 scopus 로고    scopus 로고
    • Bacteroides fragilis polysaccharide A is necessary and sufficient for acute activation of intestinal sensory neurons
    • Mao, Y.-K., D.L. Kasper, B. Wang, et al. 2013. Bacteroides fragilis polysaccharide A is necessary and sufficient for acute activation of intestinal sensory neurons. Nat. Commun. 4: 1465.
    • (2013) Nat. Commun. , vol.4 , pp. 1465
    • Mao, Y.-K.1    Kasper, D.L.2    Wang, B.3


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