Prebiotic administration normalizes lipopolysaccharide (LPS)-induced anxiety and cortical 5-HT2A receptor and IL1-β levels in male mice

Brain, Behavior, and Immunity

Volumn 52, Issue , 2016, Pages 120-131

  Savignac, Helene M ^a   Couch, Yvonne ^b   Stratford, Michael ^b   Bannerman, David M ^b   Tzortzis, George ^a   Anthony, Daniel C ^b   Burnet, Philip W J ^b  

^a Clasado Ltd   (United Kingdom)

^b UNIVERSITY OF OXFORD   (United Kingdom)

Author keywords

5 HT2A receptor; Behaviour; BGOS; Cytokines; Frontal cortex; Inflammation; Microbiota; NMDA receptor

Indexed keywords

5 HYDROXYINDOLEACETIC ACID; INTERLEUKIN 1BETA; INTERLEUKIN 6; LIPOPOLYSACCHARIDE; N METHYL DEXTRO ASPARTIC ACID RECEPTOR; PREBIOTIC AGENT; SEROTONIN; SEROTONIN 1A RECEPTOR; SEROTONIN 2A RECEPTOR; TUMOR NECROSIS FACTOR ALPHA; CYTOKINE;

ADULT; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIINFLAMMATORY ACTIVITY; ANXIETY DISORDER; ANXIOLYTIC EFFECT; ARTICLE; BIFIDOBACTERIUM; CD-1 MOUSE; CONTROLLED STUDY; DIET SUPPLEMENTATION; DRUG EFFECT; FRONTAL CORTEX; GLUTAMATERGIC SYSTEM; LATENT PERIOD; LOCOMOTION; MALE; MARBLE BURYING TEST; MOLECULAR DYNAMICS; MOUSE; NERVOUS SYSTEM; NONHUMAN; OUTCOME ASSESSMENT; PILOT STUDY; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; SEROTONINERGIC SYSTEM; TREATMENT DURATION; ANIMAL; ANXIETY; CHEMICALLY INDUCED; DIET THERAPY; DISEASE MODEL; DRUG EFFECTS; FRONTAL LOBE; HIPPOCAMPUS; ILLNESS BEHAVIOR; INFLAMMATION; INTESTINE FLORA; METABOLISM; PSYCHOLOGY;

ANIMALS; ANXIETY; CYTOKINES; DISEASE MODELS, ANIMAL; FRONTAL LOBE; GASTROINTESTINAL MICROBIOME; HIPPOCAMPUS; ILLNESS BEHAVIOR; INFLAMMATION; INTERLEUKIN-1BETA; LIPOPOLYSACCHARIDES; MALE; MICE; PREBIOTICS; RECEPTOR, SEROTONIN, 5-HT2A; RECEPTORS, N-METHYL-D-ASPARTATE; SEROTONIN;

EID: 84953369399     PISSN: 08891591     EISSN: 10902139     Source Type: Journal    
DOI: 10.1016/j.bbi.2015.10.007     Document Type: Article

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