Dysbiosis in the gut microbiota of patients with multiple sclerosis, with a striking depletion of species belonging to clostridia XIVa and IV clusters

PLoS ONE

Volumn 10, Issue 9, 2015, Pages

  Miyake, Sachiko ^a,b   Kim, Sangwan ^c   Suda, Wataru ^c   Oshima, Kenshiro ^c   Nakamura, Masakazu ^a   Matsuoka, Takako ^a   Chihara, Norio ^a   Tomita, Atsuko ^a   Sato, Wakiro ^a   Kim, Seok Won ^c,d   Morita, Hidetoshi ^e   Hattori, Masahira ^c   Yamamura, Takashi ^a  

^a NATIONAL INSTITUTE OF NEUROSCIENCE   (Japan)

^b JUNTENDO UNIVERSITY   (Japan)

^c UNIVERSITY OF TOKYO   (Japan)

^d Institute of Physical and Chemical Research   (Japan)

^e AZABU UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

RNA 16S; BACTERIAL RNA;

16S RIBOSOMAL RNA GENE; ADULT; ARTICLE; BACTERIAL GENE; BACTEROIDETES; CLINICAL ARTICLE; CLOSTRIDIA; CONTROLLED STUDY; DYSBIOSIS; FEMALE; HUMAN; INTESTINE FLORA; JAPANESE (PEOPLE); MALE; MULTIPLE SCLEROSIS; PHYLOGENETIC TREE; PYROSEQUENCING; REGULATORY T LYMPHOCYTE; SPECIES DIVERSITY; SPECIES RICHNESS; CLASSIFICATION; CLOSTRIDIUM; CONTROLLED CLINICAL TRIAL; GENETICS; HIGH THROUGHPUT SEQUENCING; JAPAN; METABOLISM; MICROBIOLOGY; PATHOPHYSIOLOGY; SEQUENCE ANALYSIS;

ADULT; BACTEROIDETES; CLOSTRIDIUM; DYSBIOSIS; FEMALE; GASTROINTESTINAL MICROBIOME; HIGH-THROUGHPUT NUCLEOTIDE SEQUENCING; HUMANS; JAPAN; MALE; MULTIPLE SCLEROSIS; RNA, BACTERIAL; RNA, RIBOSOMAL, 16S; SEQUENCE ANALYSIS, RNA;

EID: 84947447931     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0137429     Document Type: Article

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