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Volumn 32, Issue 5, 2017, Pages 739-749

Parkinson's disease and Parkinson's disease medications have distinct signatures of the gut microbiome

Author keywords

confounding; functional pathways; gut microbiome; medications; Parkinson's disease

Indexed keywords

AMANTADINE; ANTIPARKINSON AGENT; CARBIDOPA PLUS LEVODOPA; CATECHOL METHYLTRANSFERASE INHIBITOR; CHOLINERGIC RECEPTOR BLOCKING AGENT; MONOAMINE OXIDASE INHIBITOR; XENOBIOTIC AGENT; CARBIDOPA; CARBIDOPA, LEVODOPA DRUG COMBINATION; LEVODOPA; RNA 16S;

EID: 85013158306     PISSN: 08853185     EISSN: 15318257     Source Type: Journal    
DOI: 10.1002/mds.26942     Document Type: Article
Times cited : (662)

References (54)
  • 1
    • 84891447160 scopus 로고    scopus 로고
    • Gastrointestinal manifestations in Parkinson's disease: prevalence and occurrence before motor symptoms
    • Cersosimo MG, Raina GB, Pecci C, et al. Gastrointestinal manifestations in Parkinson's disease: prevalence and occurrence before motor symptoms. J Neurol 2013;260(5):1332–1338.
    • (2013) J Neurol , vol.260 , Issue.5 , pp. 1332-1338
    • Cersosimo, M.G.1    Raina, G.B.2    Pecci, C.3
  • 2
    • 84962755420 scopus 로고    scopus 로고
    • Neuropathological basis of nonmotor manifestations of Parkinson's disease
    • Adler CH, Beach TG. Neuropathological basis of nonmotor manifestations of Parkinson's disease. Mov Disord 2016;31(8):1114–1119.
    • (2016) Mov Disord , vol.31 , Issue.8 , pp. 1114-1119
    • Adler, C.H.1    Beach, T.G.2
  • 3
    • 84867823011 scopus 로고    scopus 로고
    • Colonic inflammation in Parkinson's disease
    • Devos D, Lebouvier T, Lardeux B, et al. Colonic inflammation in Parkinson's disease. Neurobiol Dis 2013;50:42–48.
    • (2013) Neurobiol Dis , vol.50 , pp. 42-48
    • Devos, D.1    Lebouvier, T.2    Lardeux, B.3
  • 4
    • 82455206282 scopus 로고    scopus 로고
    • Increased intestinal permeability correlates with sigmoid mucosa alpha-synuclein staining and endotoxin exposure markers in early Parkinson's disease
    • Forsyth CB, Shannon KM, Kordower JH, et al. Increased intestinal permeability correlates with sigmoid mucosa alpha-synuclein staining and endotoxin exposure markers in early Parkinson's disease. PLoS One 2011;6(12):e28032.
    • (2011) PLoS One , vol.6 , Issue.12
    • Forsyth, C.B.1    Shannon, K.M.2    Kordower, J.H.3
  • 5
    • 84942366331 scopus 로고    scopus 로고
    • Vagotomy and subsequent risk of Parkinson's disease
    • Svensson E, Horvath-Puho E, Thomsen RW, et al. Vagotomy and subsequent risk of Parkinson's disease. Ann Neurol 2015;78(4):522–529.
    • (2015) Ann Neurol , vol.78 , Issue.4 , pp. 522-529
    • Svensson, E.1    Horvath-Puho, E.2    Thomsen, R.W.3
  • 6
    • 84968918909 scopus 로고    scopus 로고
    • Population-level analysis of gut microbiome variation
    • Falony G, Joossens M, Vieira-Silva S, et al. Population-level analysis of gut microbiome variation. Science 2016;352(6285):560–564.
    • (2016) Science , vol.352 , Issue.6285 , pp. 560-564
    • Falony, G.1    Joossens, M.2    Vieira-Silva, S.3
  • 7
    • 84968901892 scopus 로고    scopus 로고
    • Population-based metagenomics analysis reveals markers for gut microbiome composition and diversity
    • Zhernakova A, Kurilshikov A, Bonder MJ, et al. Population-based metagenomics analysis reveals markers for gut microbiome composition and diversity. Science 2016;352(6285):565–569.
    • (2016) Science , vol.352 , Issue.6285 , pp. 565-569
    • Zhernakova, A.1    Kurilshikov, A.2    Bonder, M.J.3
  • 8
    • 84978863785 scopus 로고    scopus 로고
    • Emerging technologies for gut microbiome research
    • Arnold JW, Roach J, Azcarate-Peril MA. Emerging technologies for gut microbiome research. Trends Microbiol 2016;24(11):887–901.
    • (2016) Trends Microbiol , vol.24 , Issue.11 , pp. 887-901
    • Arnold, J.W.1    Roach, J.2    Azcarate-Peril, M.A.3
  • 9
    • 84949772416 scopus 로고    scopus 로고
    • Disentangling type 2 diabetes and metformin treatment signatures in the human gut microbiota
    • Forslund K, Hildebrand F, Nielsen T, et al. Disentangling type 2 diabetes and metformin treatment signatures in the human gut microbiota. Nature 2015;528(7581):262–266.
    • (2015) Nature , vol.528 , Issue.7581 , pp. 262-266
    • Forslund, K.1    Hildebrand, F.2    Nielsen, T.3
  • 10
    • 85001930733 scopus 로고    scopus 로고
    • Gut microbiota regulate motor deficits and neuroinflammation in a model of Parkinson's disease
    • e12
    • Sampson TR, Debelius JW, Thron T, et al. Gut microbiota regulate motor deficits and neuroinflammation in a model of Parkinson's disease. Cell 2016;167(6):1469–1480.e12.
    • (2016) Cell , vol.167 , Issue.6 , pp. 1469-1480
    • Sampson, T.R.1    Debelius, J.W.2    Thron, T.3
  • 11
    • 84924577956 scopus 로고    scopus 로고
    • Gut microbiota are related to Parkinson's disease and clinical phenotype
    • Scheperjans F, Aho V, Pereira PA, et al. Gut microbiota are related to Parkinson's disease and clinical phenotype. Mov Disord 2015;30(3):350–358.
    • (2015) Mov Disord , vol.30 , Issue.3 , pp. 350-358
    • Scheperjans, F.1    Aho, V.2    Pereira, P.A.3
  • 12
    • 84941167046 scopus 로고    scopus 로고
    • Colonic bacterial composition in Parkinson's disease
    • Keshavarzian A, Green SJ, Engen PA, et al. Colonic bacterial composition in Parkinson's disease. Mov Disord 2015;30(10):1351–1360.
    • (2015) Mov Disord , vol.30 , Issue.10 , pp. 1351-1360
    • Keshavarzian, A.1    Green, S.J.2    Engen, P.A.3
  • 13
    • 84951284320 scopus 로고    scopus 로고
    • Intestinal dysbiosis and lowered serum lipopolysaccharide-binding protein in Parkinson's disease
    • Hasegawa S, Goto S, Tsuji H, et al. Intestinal dysbiosis and lowered serum lipopolysaccharide-binding protein in Parkinson's disease. PLoS One 2015;10(11):e0142164.
    • (2015) PLoS One , vol.10 , Issue.11
    • Hasegawa, S.1    Goto, S.2    Tsuji, H.3
  • 14
    • 84994745714 scopus 로고    scopus 로고
    • Short chain fatty acids and gut microbiota differ between patients with Parkinson's disease and age-matched controls
    • Unger MM, Spiegel J, Dillmann KU, et al. Short chain fatty acids and gut microbiota differ between patients with Parkinson's disease and age-matched controls. Parkinsonism Relat Disord 2016;32:66–72.
    • (2016) Parkinsonism Relat Disord , vol.32 , pp. 66-72
    • Unger, M.M.1    Spiegel, J.2    Dillmann, K.U.3
  • 15
    • 77956646167 scopus 로고    scopus 로고
    • Common genetic variation in the HLA region is associated with late-onset sporadic Parkinson's disease
    • Hamza TH, Zabetian CP, Tenesa A, et al. Common genetic variation in the HLA region is associated with late-onset sporadic Parkinson's disease. Nat Genet 2010;42(9):781–785.
    • (2010) Nat Genet , vol.42 , Issue.9 , pp. 781-785
    • Hamza, T.H.1    Zabetian, C.P.2    Tenesa, A.3
  • 16
    • 0026514953 scopus 로고
    • Accuracy of clinical diagnosis of idiopathic Parkinson's disease: a clinico-pathological study of 100 cases
    • Hughes AJ, Daniel SE, Kilford L, Lees AJ. Accuracy of clinical diagnosis of idiopathic Parkinson's disease: a clinico-pathological study of 100 cases. J Neurol Neurosurg Psychiatry 1992;55:181–184.
    • (1992) J Neurol Neurosurg Psychiatry , vol.55 , pp. 181-184
    • Hughes, A.J.1    Daniel, S.E.2    Kilford, L.3    Lees, A.J.4
  • 17
    • 84863981120 scopus 로고    scopus 로고
    • Ultra-high-throughput microbial community analysis on the Illumina HiSeq and MiSeq platforms
    • Caporaso JG, Lauber CL, Walters WA, et al. Ultra-high-throughput microbial community analysis on the Illumina HiSeq and MiSeq platforms. ISME J 2012;6(8):1621–1624.
    • (2012) ISME J , vol.6 , Issue.8 , pp. 1621-1624
    • Caporaso, J.G.1    Lauber, C.L.2    Walters, W.A.3
  • 18
    • 79952005915 scopus 로고    scopus 로고
    • Global patterns of 16S rRNA diversity at a depth of millions of sequences per sample
    • Caporaso JG, Lauber CL, Walters WA, et al. Global patterns of 16S rRNA diversity at a depth of millions of sequences per sample. Proc Natl Acad Sci U S A 2011;108(suppl 1):4516–4522.
    • (2011) Proc Natl Acad Sci U S A , vol.108 , pp. 4516-4522
    • Caporaso, J.G.1    Lauber, C.L.2    Walters, W.A.3
  • 20
    • 84870814915 scopus 로고    scopus 로고
    • SortMeRNA: fast and accurate filtering of ribosomal RNAs in metatranscriptomic data
    • Kopylova E, Noe L, Touzet H. SortMeRNA: fast and accurate filtering of ribosomal RNAs in metatranscriptomic data. Bioinformatics 2012;28(24):3211–3217.
    • (2012) Bioinformatics , vol.28 , Issue.24 , pp. 3211-3217
    • Kopylova, E.1    Noe, L.2    Touzet, H.3
  • 21
    • 84857122937 scopus 로고    scopus 로고
    • An improved Greengenes taxonomy with explicit ranks for ecological and evolutionary analyses of bacteria and archaea
    • McDonald D, Price MN, Goodrich J, et al. An improved Greengenes taxonomy with explicit ranks for ecological and evolutionary analyses of bacteria and archaea. ISME J 2012;6(3):610–618.
    • (2012) ISME J , vol.6 , Issue.3 , pp. 610-618
    • McDonald, D.1    Price, M.N.2    Goodrich, J.3
  • 22
    • 84960126272 scopus 로고    scopus 로고
    • Improved taxonomic assignment of human intestinal 16S rRNA sequences by a dedicated reference database
    • Ritari J, Salojarvi J, Lahti L, de Vos WM. Improved taxonomic assignment of human intestinal 16S rRNA sequences by a dedicated reference database. BMC Genomics 2015;16:1056.
    • (2015) BMC Genomics , vol.16 , pp. 1056
    • Ritari, J.1    Salojarvi, J.2    Lahti, L.3    de Vos, W.M.4
  • 23
    • 34548293679 scopus 로고    scopus 로고
    • Naive Bayesian classifier for rapid assignment of rRNA sequences into the new bacterial taxonomy
    • Wang Q, Garrity GM, Tiedje JM, Cole JR. Naive Bayesian classifier for rapid assignment of rRNA sequences into the new bacterial taxonomy. Appl Environ Microbiol 2007;73(16):5261–5267.
    • (2007) Appl Environ Microbiol , vol.73 , Issue.16 , pp. 5261-5267
    • Wang, Q.1    Garrity, G.M.2    Tiedje, J.M.3    Cole, J.R.4
  • 24
    • 29144464937 scopus 로고    scopus 로고
    • UniFrac: a new phylogenetic method for comparing microbial communities
    • Lozupone C, Knight R. UniFrac: a new phylogenetic method for comparing microbial communities. Appl Environ Microbiol 2005;71(12):8228–8235.
    • (2005) Appl Environ Microbiol , vol.71 , Issue.12 , pp. 8228-8235
    • Lozupone, C.1    Knight, R.2
  • 25
    • 0001939623 scopus 로고
    • Computer programs for hierarchical polythetic classification (“similarity analyses”)
    • Lance GN, Williams WT. Computer programs for hierarchical polythetic classification (“similarity analyses”). Comput J 1966;9(1):60–64.
    • (1966) Comput J , vol.9 , Issue.1 , pp. 60-64
    • Lance, G.N.1    Williams, W.T.2
  • 26
    • 0031013467 scopus 로고    scopus 로고
    • Similarity measure bias in river benthic Aufwuchs community analysis
    • Cao Y, Williams WP, Bark AW. Similarity measure bias in river benthic Aufwuchs community analysis. Water Environ Res 1997;69(1):95–106.
    • (1997) Water Environ Res , vol.69 , Issue.1 , pp. 95-106
    • Cao, Y.1    Williams, W.P.2    Bark, A.W.3
  • 27
    • 0002154022 scopus 로고    scopus 로고
    • A new method for non-parametric multivariate analysis of variance
    • Anderson MJ. A new method for non-parametric multivariate analysis of variance. Austral Ecol 2001;26(1):32–46.
    • (2001) Austral Ecol , vol.26 , Issue.1 , pp. 32-46
    • Anderson, M.J.1
  • 30
    • 84884127512 scopus 로고    scopus 로고
    • Predictive functional profiling of microbial communities using 16S rRNA marker gene sequences
    • Langille MG, Zaneveld J, Caporaso JG, et al. Predictive functional profiling of microbial communities using 16S rRNA marker gene sequences. Nat Biotechnol 2013;31(9):814–821.
    • (2013) Nat Biotechnol , vol.31 , Issue.9 , pp. 814-821
    • Langille, M.G.1    Zaneveld, J.2    Caporaso, J.G.3
  • 32
    • 84911429654 scopus 로고    scopus 로고
    • STAMP: statistical analysis of taxonomic and functional profiles
    • Parks DH, Tyson GW, Hugenholtz P, Beiko RG. STAMP: statistical analysis of taxonomic and functional profiles. Bioinformatics 2014;30(21):3123–3124.
    • (2014) Bioinformatics , vol.30 , Issue.21 , pp. 3123-3124
    • Parks, D.H.1    Tyson, G.W.2    Hugenholtz, P.3    Beiko, R.G.4
  • 33
    • 0034095886 scopus 로고    scopus 로고
    • Clinical pharmacology, therapeutic use and potential of COMT inhibitors in Parkinson's disease
    • Kaakkola S. Clinical pharmacology, therapeutic use and potential of COMT inhibitors in Parkinson's disease. Drugs 2000;59(6):1233–1250.
    • (2000) Drugs , vol.59 , Issue.6 , pp. 1233-1250
    • Kaakkola, S.1
  • 34
    • 33646803001 scopus 로고    scopus 로고
    • Anticholinergic medications in community-dwelling older veterans: prevalence of anticholinergic symptoms, symptom burden, and adverse drug events
    • Ness J, Hoth A, Barnett MJ, Shorr RI, Kaboli PJ. Anticholinergic medications in community-dwelling older veterans: prevalence of anticholinergic symptoms, symptom burden, and adverse drug events. Am J Geriatr Pharmacother 2006;4(1):42–51.
    • (2006) Am J Geriatr Pharmacother , vol.4 , Issue.1 , pp. 42-51
    • Ness, J.1    Hoth, A.2    Barnett, M.J.3    Shorr, R.I.4    Kaboli, P.J.5
  • 35
    • 77956414742 scopus 로고    scopus 로고
    • Protection of dopaminergic cells from MPP+-mediated toxicity by histone deacetylase inhibition
    • Kidd SK, Schneider JS. Protection of dopaminergic cells from MPP+-mediated toxicity by histone deacetylase inhibition. Brain Res 2010;1354:172–178.
    • (2010) Brain Res , vol.1354 , pp. 172-178
    • Kidd, S.K.1    Schneider, J.S.2
  • 36
    • 84879420897 scopus 로고    scopus 로고
    • Sodium butyrate improves locomotor impairment and early mortality in a rotenone-induced Drosophila model of Parkinson's disease
    • St Laurent R, O'Brien LM, Ahmad ST. Sodium butyrate improves locomotor impairment and early mortality in a rotenone-induced Drosophila model of Parkinson's disease. Neuroscience 2013;246:382–390.
    • (2013) Neuroscience , vol.246 , pp. 382-390
    • St Laurent, R.1    O'Brien, L.M.2    Ahmad, S.T.3
  • 37
    • 84930935446 scopus 로고    scopus 로고
    • Beneficial effects of sodium butyrate in 6-OHDA induced neurotoxicity and behavioral abnormalities: Modulation of histone deacetylase activity
    • Sharma S, Taliyan R, Singh S. Beneficial effects of sodium butyrate in 6-OHDA induced neurotoxicity and behavioral abnormalities: Modulation of histone deacetylase activity. Behav Brain Res 2015;291:306–314.
    • (2015) Behav Brain Res , vol.291 , pp. 306-314
    • Sharma, S.1    Taliyan, R.2    Singh, S.3
  • 38
    • 1642277665 scopus 로고    scopus 로고
    • Restricted distribution of the butyrate kinase pathway among butyrate-producing bacteria from the human colon
    • Louis P, Duncan SH, McCrae SI, Millar J, Jackson MS, Flint HJ. Restricted distribution of the butyrate kinase pathway among butyrate-producing bacteria from the human colon. J Bacteriol 2004;186(7):2099–2106.
    • (2004) J Bacteriol , vol.186 , Issue.7 , pp. 2099-2106
    • Louis, P.1    Duncan, S.H.2    McCrae, S.I.3    Millar, J.4    Jackson, M.S.5    Flint, H.J.6
  • 39
    • 0029009026 scopus 로고
    • Cloning, characterization, and functional expression of acs, the gene which encodes acetyl coenzyme A synthetase in Escherichia coli
    • Kumari S, Tishel R, Eisenbach M, Wolfe AJ. Cloning, characterization, and functional expression of acs, the gene which encodes acetyl coenzyme A synthetase in Escherichia coli. J Bacteriol 1995;177(10):2878–2886.
    • (1995) J Bacteriol , vol.177 , Issue.10 , pp. 2878-2886
    • Kumari, S.1    Tishel, R.2    Eisenbach, M.3    Wolfe, A.J.4
  • 40
    • 84933043202 scopus 로고    scopus 로고
    • Host microbiota constantly control maturation and function of microglia in the CNS
    • Erny D, Hrabe de Angelis AL, Jaitin D, et al. Host microbiota constantly control maturation and function of microglia in the CNS. Nat Neurosci 2015;18(7):965–977.
    • (2015) Nat Neurosci , vol.18 , Issue.7 , pp. 965-977
    • Erny, D.1    Hrabe de Angelis, A.L.2    Jaitin, D.3
  • 41
    • 84983032256 scopus 로고    scopus 로고
    • The relation between alpha-synuclein and microglia in Parkinson's disease: recent developments
    • Sanchez-Guajardo V, Tentillier N, Romero-Ramos M. The relation between alpha-synuclein and microglia in Parkinson's disease: recent developments. Neuroscience 2015;302:47–58.
    • (2015) Neuroscience , vol.302 , pp. 47-58
    • Sanchez-Guajardo, V.1    Tentillier, N.2    Romero-Ramos, M.3
  • 42
    • 79955579989 scopus 로고    scopus 로고
    • The microbiome and butyrate regulate energy metabolism and autophagy in the mammalian colon
    • Donohoe DR, Garge N, Zhang X, et al. The microbiome and butyrate regulate energy metabolism and autophagy in the mammalian colon. Cell Metab 2011;13(5):517–526.
    • (2011) Cell Metab , vol.13 , Issue.5 , pp. 517-526
    • Donohoe, D.R.1    Garge, N.2    Zhang, X.3
  • 44
    • 0033863238 scopus 로고    scopus 로고
    • Butyrate inhibits inflammatory responses through NFkappaB inhibition: implications for Crohn's disease
    • Segain JP, Raingeard de la Bletiere D, Bourreille A, et al. Butyrate inhibits inflammatory responses through NFkappaB inhibition: implications for Crohn's disease. Gut 2000;47(3):397–403.
    • (2000) Gut , vol.47 , Issue.3 , pp. 397-403
    • Segain, J.P.1    Raingeard de la Bletiere, D.2    Bourreille, A.3
  • 45
    • 84890564250 scopus 로고    scopus 로고
    • Commensal microbe-derived butyrate induces the differentiation of colonic regulatory T cells
    • Furusawa Y, Obata Y, Fukuda S, et al. Commensal microbe-derived butyrate induces the differentiation of colonic regulatory T cells. Nature 2013;504(7480):446–450.
    • (2013) Nature , vol.504 , Issue.7480 , pp. 446-450
    • Furusawa, Y.1    Obata, Y.2    Fukuda, S.3
  • 46
    • 84938770891 scopus 로고    scopus 로고
    • Reduction of butyrate- and methane-producing microorganisms in patients with irritable bowel syndrome
    • Pozuelo M, Panda S, Santiago A, et al. Reduction of butyrate- and methane-producing microorganisms in patients with irritable bowel syndrome. Sci Rep 2015;5:12693.
    • (2015) Sci Rep , vol.5 , pp. 12693
    • Pozuelo, M.1    Panda, S.2    Santiago, A.3
  • 47
    • 84867074831 scopus 로고    scopus 로고
    • A metagenome-wide association study of gut microbiota in type 2 diabetes
    • Qin J, Li Y, Cai Z, et al. A metagenome-wide association study of gut microbiota in type 2 diabetes. Nature 2012;490(7418):55–60.
    • (2012) Nature , vol.490 , Issue.7418 , pp. 55-60
    • Qin, J.1    Li, Y.2    Cai, Z.3
  • 48
    • 84907225684 scopus 로고    scopus 로고
    • Alterations of the human gut microbiome in liver cirrhosis
    • Qin N, Yang F, Li A, et al. Alterations of the human gut microbiome in liver cirrhosis. Nature 2014;513(7516):59–64.
    • (2014) Nature , vol.513 , Issue.7516 , pp. 59-64
    • Qin, N.1    Yang, F.2    Li, A.3
  • 49
    • 84957586814 scopus 로고    scopus 로고
    • Intestinal microbiota distinguish gout patients from healthy humans
    • Guo Z, Zhang J, Wang Z, et al. Intestinal microbiota distinguish gout patients from healthy humans. Sci Rep 2016;6:20602.
    • (2016) Sci Rep , vol.6 , pp. 20602
    • Guo, Z.1    Zhang, J.2    Wang, Z.3
  • 50
    • 84932101014 scopus 로고    scopus 로고
    • Rapid and Sustained long-term decrease of fecal short-chain fatty acids in critically ill patients with systemic inflammatory response syndrome
    • Yamada T, Shimizu K, Ogura H, et al. Rapid and Sustained long-term decrease of fecal short-chain fatty acids in critically ill patients with systemic inflammatory response syndrome. J Parenter Enteral Nutr 2015;39(5):569–577.
    • (2015) J Parenter Enteral Nutr , vol.39 , Issue.5 , pp. 569-577
    • Yamada, T.1    Shimizu, K.2    Ogura, H.3
  • 52
    • 84867230531 scopus 로고    scopus 로고
    • Pesticide exposure and Parkinson's disease: epidemiological evidence of association
    • Freire C, Koifman S. Pesticide exposure and Parkinson's disease: epidemiological evidence of association. Neurotoxicology 2012;33(5):947–971.
    • (2012) Neurotoxicology , vol.33 , Issue.5 , pp. 947-971
    • Freire, C.1    Koifman, S.2
  • 54
    • 85027927719 scopus 로고    scopus 로고
    • Enterotypes of the human gut microbiome
    • Arumugam M, Raes J, Pelletier E, et al. Enterotypes of the human gut microbiome. Nature 2011;473(7346):174–180.
    • (2011) Nature , vol.473 , Issue.7346 , pp. 174-180
    • Arumugam, M.1    Raes, J.2    Pelletier, E.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.