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Volumn 86, Issue , 2018, Pages 95-101

Evidence supporting a mechanistic role of sirtuins in mood and metabolic disorders

Author keywords

Bipolar; Depression; Disorder; Metabolic; Mood; Sirtuins

Indexed keywords

ENZYME ACTIVATOR; GLUCOSE; INSULIN; PLACEBO; RESVERATROL; SIRTUIN; SIRTUIN 1; SIRTUIN 2; SIRTUIN 3; SRT 2104; UNCLASSIFIED DRUG;

EID: 85047458142     PISSN: 02785846     EISSN: 18784216     Source Type: Journal    
DOI: 10.1016/j.pnpbp.2018.05.017     Document Type: Review
Times cited : (33)

References (70)
  • 3
    • 85014244124 scopus 로고    scopus 로고
    • Molecular mechanisms in mood regulation involving the circadian clock
    • Albrecht, U., Molecular mechanisms in mood regulation involving the circadian clock. Front. Neurol., 8, 2017, 30.
    • (2017) Front. Neurol. , vol.8 , pp. 30
    • Albrecht, U.1
  • 4
    • 69249116960 scopus 로고    scopus 로고
    • SIRT1 controls the transcription of the peroxisome proliferator-activated receptor-γ co-activator-1α (PGC-1α) gene in skeletal muscle through the PGC-1α autoregulatory loop and interaction with MyoD
    • Amat, R., Planavila, A., Chen, S.L., Iglesias, R., Giralt, M., Villarroya, F., SIRT1 controls the transcription of the peroxisome proliferator-activated receptor-γ co-activator-1α (PGC-1α) gene in skeletal muscle through the PGC-1α autoregulatory loop and interaction with MyoD. J. Biol. Chem. ASBMB 284 (2009), 21872–21880.
    • (2009) J. Biol. Chem. ASBMB , vol.284 , pp. 21872-21880
    • Amat, R.1    Planavila, A.2    Chen, S.L.3    Iglesias, R.4    Giralt, M.5    Villarroya, F.6
  • 6
    • 47749140333 scopus 로고    scopus 로고
    • SIRT1 regulates circadian clock gene expression through PER2 deacetylation
    • Asher, G., Gatfield, D., Stratmann, M., Reinke, H., Dibner, C., Kreppel, F. et al., SIRT1 regulates circadian clock gene expression through PER2 deacetylation. Cell 134 (2008), 317–328.
    • (2008) Cell , vol.134 , pp. 317-328
    • Asher, G.1    Gatfield, D.2    Stratmann, M.3    Reinke, H.4    Dibner, C.5    Kreppel, F.6
  • 8
    • 33751072349 scopus 로고    scopus 로고
    • Resveratrol improves health and survival of mice on a high-calorie diet
    • Baur, J.A., Pearson, K.J., Price, N.L., Jamieson, H.A., Lerin, C., Kalra, A. et al., Resveratrol improves health and survival of mice on a high-calorie diet. Nature 444 (2006), 337–342.
    • (2006) Nature , vol.444 , pp. 337-342
    • Baur, J.A.1    Pearson, K.J.2    Price, N.L.3    Jamieson, H.A.4    Lerin, C.5    Kalra, A.6
  • 9
    • 84902087370 scopus 로고    scopus 로고
    • An updated meta-analysis of oxidative stress markers in bipolar disorder
    • Brown, N.C., Andreazza, A.C., Young, L.T., An updated meta-analysis of oxidative stress markers in bipolar disorder. Psychiatry Res. 218 (2014), 61–68.
    • (2014) Psychiatry Res. , vol.218 , pp. 61-68
    • Brown, N.C.1    Andreazza, A.C.2    Young, L.T.3
  • 10
    • 84899498150 scopus 로고    scopus 로고
    • The SIRT1 deacetylase protects mice against the symptoms of metabolic syndrome
    • Caron, A.Z., He, X., Mottawea, W., Seifert, E.L., Jardine, K., Dewar-Darch, D. et al., The SIRT1 deacetylase protects mice against the symptoms of metabolic syndrome. FASEB J. 28 (2014), 1306–1316.
    • (2014) FASEB J. , vol.28 , pp. 1306-1316
    • Caron, A.Z.1    He, X.2    Mottawea, W.3    Seifert, E.L.4    Jardine, K.5    Dewar-Darch, D.6
  • 11
    • 84879391795 scopus 로고    scopus 로고
    • SIRT1 mediates central circadian control in the SCN by a mechanism that decays with aging
    • Chang, H.-C., Guarente, L., SIRT1 mediates central circadian control in the SCN by a mechanism that decays with aging. Cell 153 (2013), 1448–1460.
    • (2013) Cell , vol.153 , pp. 1448-1460
    • Chang, H.-C.1    Guarente, L.2
  • 12
    • 84900303381 scopus 로고    scopus 로고
    • Impact of circadian nuclear receptor REV-ERBα on midbrain dopamine production and mood regulation
    • Chung, S., Lee, E.J., Yun, S., Choe, H.K., Park, S.-B., Son, H.J. et al., Impact of circadian nuclear receptor REV-ERBα on midbrain dopamine production and mood regulation. Cell 157 (2014), 858–868.
    • (2014) Cell , vol.157 , pp. 858-868
    • Chung, S.1    Lee, E.J.2    Yun, S.3    Choe, H.K.4    Park, S.-B.5    Son, H.J.6
  • 13
    • 75349111140 scopus 로고    scopus 로고
    • Regulation of succinate dehydrogenase activity by SIRT3 in mammalian mitochondria
    • Cimen, H., Han, M.-J., Yang, Y., Tong, Q., Koc, H., Koc, E.C., Regulation of succinate dehydrogenase activity by SIRT3 in mammalian mitochondria. Biochemistry 49 (2010), 304–311.
    • (2010) Biochemistry , vol.49 , pp. 304-311
    • Cimen, H.1    Han, M.-J.2    Yang, Y.3    Tong, Q.4    Koc, H.5    Koc, E.C.6
  • 15
    • 84938379545 scopus 로고    scopus 로고
    • Sparse whole-genome sequencing identifies two loci for major depressive disorder
    • CONVERGE consortium, Sparse whole-genome sequencing identifies two loci for major depressive disorder. Nature 523 (2015), 588–591.
    • (2015) Nature , vol.523 , pp. 588-591
    • CONVERGE consortium1
  • 16
    • 84986277770 scopus 로고    scopus 로고
    • SIRT1 overexpression in mouse Hippocampus induces cognitive enhancement through Proteostatic and neurotrophic mechanisms
    • Corpas, R., Revilla, S., Ursulet, S., Castro-Freire, M., Kaliman, P., Petegnief, V. et al., SIRT1 overexpression in mouse Hippocampus induces cognitive enhancement through Proteostatic and neurotrophic mechanisms. Mol. Neurobiol. 54 (2017), 5604–5619.
    • (2017) Mol. Neurobiol. , vol.54 , pp. 5604-5619
    • Corpas, R.1    Revilla, S.2    Ursulet, S.3    Castro-Freire, M.4    Kaliman, P.5    Petegnief, V.6
  • 17
    • 29644447464 scopus 로고    scopus 로고
    • Nutritional status, cognition, and survival: a new role for leptin and AMP kinase
    • Dagon, Y., Avraham, Y., Magen, I., Gertler, A., Ben-Hur, T., Berry, E.M., Nutritional status, cognition, and survival: a new role for leptin and AMP kinase. J. Biol. Chem. 280 (2005), 42142–42148.
    • (2005) J. Biol. Chem. , vol.280 , pp. 42142-42148
    • Dagon, Y.1    Avraham, Y.2    Magen, I.3    Gertler, A.4    Ben-Hur, T.5    Berry, E.M.6
  • 19
    • 77956185062 scopus 로고    scopus 로고
    • A novel pathway regulates memory and plasticity via SIRT1 and miR-134
    • Gao, J., Wang, W.-Y., Mao, Y.-W., Gräff, J., Guan, J.-S., Pan, L. et al., A novel pathway regulates memory and plasticity via SIRT1 and miR-134. Nature 466 (2010), 1105–1109.
    • (2010) Nature , vol.466 , pp. 1105-1109
    • Gao, J.1    Wang, W.-Y.2    Mao, Y.-W.3    Gräff, J.4    Guan, J.-S.5    Pan, L.6
  • 20
    • 34247259630 scopus 로고    scopus 로고
    • Metabolic control of muscle mitochondrial function and fatty acid oxidation through SIRT1/PGC-1α
    • Gerhart-Hines, Z., Rodgers, J.T., Bare, O., Lerin, C., Kim, S.-H., Mostoslavsky, R. et al., Metabolic control of muscle mitochondrial function and fatty acid oxidation through SIRT1/PGC-1α. EMBO J. 26 (2007), 1913–1923.
    • (2007) EMBO J. , vol.26 , pp. 1913-1923
    • Gerhart-Hines, Z.1    Rodgers, J.T.2    Bare, O.3    Lerin, C.4    Kim, S.-H.5    Mostoslavsky, R.6
  • 21
    • 84946227815 scopus 로고    scopus 로고
    • Emerging role of Sirtuin 2 in the regulation of mammalian metabolism
    • Gomes, P., Outeiro, T.F., Cavadas, C., Emerging role of Sirtuin 2 in the regulation of mammalian metabolism. Trends Pharmacol. Sci. 36 (2015), 756–768.
    • (2015) Trends Pharmacol. Sci. , vol.36 , pp. 756-768
    • Gomes, P.1    Outeiro, T.F.2    Cavadas, C.3
  • 22
    • 33745931074 scopus 로고    scopus 로고
    • Sirtuins deacetylate and activate mammalian acetyl-CoA synthetases
    • Hallows, W.C., Lee, S., Denu, J.M., Sirtuins deacetylate and activate mammalian acetyl-CoA synthetases. Proc. Natl. Acad. Sci. U. S. A. 103 (2006), 10230–10235.
    • (2006) Proc. Natl. Acad. Sci. U. S. A. , vol.103 , pp. 10230-10235
    • Hallows, W.C.1    Lee, S.2    Denu, J.M.3
  • 23
    • 78651468707 scopus 로고    scopus 로고
    • Sirt3 promotes the urea cycle and fatty acid oxidation during dietary restriction
    • Hallows, W.C., Yu, W., Smith, B.C., Devries, M.K., Devires, M.K., Ellinger, J.J. et al., Sirt3 promotes the urea cycle and fatty acid oxidation during dietary restriction. Mol. Cell 41 (2011), 139–149.
    • (2011) Mol. Cell , vol.41 , pp. 139-149
    • Hallows, W.C.1    Yu, W.2    Smith, B.C.3    Devries, M.K.4    Devires, M.K.5    Ellinger, J.J.6
  • 24
    • 43049116816 scopus 로고    scopus 로고
    • Regulation of monoamine oxidase a by circadian-clock components implies clock influence on mood
    • Hampp, G., Ripperger, J.A., Houben, T., Schmutz, I., Blex, C., Perreau-Lenz, S. et al., Regulation of monoamine oxidase a by circadian-clock components implies clock influence on mood. Curr. Biol. 18 (2008), 678–683.
    • (2008) Curr. Biol. , vol.18 , pp. 678-683
    • Hampp, G.1    Ripperger, J.A.2    Houben, T.3    Schmutz, I.4    Blex, C.5    Perreau-Lenz, S.6
  • 25
    • 84937970004 scopus 로고    scopus 로고
    • Cardiovascular and psychiatric characteristics associated with oxidative stress markers among adolescents with bipolar disorder
    • Hatch, J., Andreazza, A., Olowoyeye, O., Rezin, G.T., Moody, A., Goldstein, B.I., Cardiovascular and psychiatric characteristics associated with oxidative stress markers among adolescents with bipolar disorder. J. Psychosom. Res. 79 (2015), 222–227.
    • (2015) J. Psychosom. Res. , vol.79 , pp. 222-227
    • Hatch, J.1    Andreazza, A.2    Olowoyeye, O.3    Rezin, G.T.4    Moody, A.5    Goldstein, B.I.6
  • 26
    • 77950806433 scopus 로고    scopus 로고
    • SIRT3 regulates mitochondrial fatty-acid oxidation by reversible enzyme deacetylation
    • Hirschey, M.D., Shimazu, T., Goetzman, E., Jing, E., Schwer, B., Lombard, D.B. et al., SIRT3 regulates mitochondrial fatty-acid oxidation by reversible enzyme deacetylation. Nature 464 (2010), 121–125.
    • (2010) Nature , vol.464 , pp. 121-125
    • Hirschey, M.D.1    Shimazu, T.2    Goetzman, E.3    Jing, E.4    Schwer, B.5    Lombard, D.B.6
  • 27
    • 0034677535 scopus 로고    scopus 로고
    • Transcriptional silencing and longevity protein Sir2 is an NAD-dependent histone deacetylase
    • Imai, S., Armstrong, C.M., Kaeberlein, M., Guarente, L., Transcriptional silencing and longevity protein Sir2 is an NAD-dependent histone deacetylase. Nature 403 (2000), 795–800.
    • (2000) Nature , vol.403 , pp. 795-800
    • Imai, S.1    Armstrong, C.M.2    Kaeberlein, M.3    Guarente, L.4
  • 28
    • 84961288488 scopus 로고    scopus 로고
    • SIRT1 is a regulator in high glucose-induced inflammatory response in RAW264.7 cells
    • Jia, Y., Zheng, Z., Wang, Y., Zhou, Q., Cai, W., Jia, W. et al., SIRT1 is a regulator in high glucose-induced inflammatory response in RAW264.7 cells. PLoS One, 10, 2015, e0120849.
    • (2015) PLoS One , vol.10
    • Jia, Y.1    Zheng, Z.2    Wang, Y.3    Zhou, Q.4    Cai, W.5    Jia, W.6
  • 30
    • 80052291180 scopus 로고    scopus 로고
    • Sirtuin-3 (Sirt3) regulates skeletal muscle metabolism and insulin signaling via altered mitochondrial oxidation and reactive oxygen species production
    • Jing, E., Emanuelli, B., Hirschey, M.D., Boucher, J., Lee, K.Y., Lombard, D. et al., Sirtuin-3 (Sirt3) regulates skeletal muscle metabolism and insulin signaling via altered mitochondrial oxidation and reactive oxygen species production. Proc. Natl. Acad. Sci. U. S. A. 108 (2011), 14608–14613.
    • (2011) Proc. Natl. Acad. Sci. U. S. A. , vol.108 , pp. 14608-14613
    • Jing, E.1    Emanuelli, B.2    Hirschey, M.D.3    Boucher, J.4    Lee, K.Y.5    Lombard, D.6
  • 33
    • 84981320357 scopus 로고    scopus 로고
    • SIRT1 mediates depression-like behaviors in the nucleus accumbens
    • Kim, H.-D., Hesterman, J., Call, T., Magazu, S., Keeley, E., Armenta, K. et al., SIRT1 mediates depression-like behaviors in the nucleus accumbens. J. Neurosci. 36 (2016), 8441–8452.
    • (2016) J. Neurosci. , vol.36 , pp. 8441-8452
    • Kim, H.-D.1    Hesterman, J.2    Call, T.3    Magazu, S.4    Keeley, E.5    Armenta, K.6
  • 34
    • 77956268388 scopus 로고    scopus 로고
    • SIRT1 gene is associated with major depressive disorder in the Japanese population
    • Kishi, T., Yoshimura, R., Kitajima, T., Okochi, T., Okumura, T., Tsunoka, T. et al., SIRT1 gene is associated with major depressive disorder in the Japanese population. J. Affect. Disord. 126 (2010), 167–173.
    • (2010) J. Affect. Disord. , vol.126 , pp. 167-173
    • Kishi, T.1    Yoshimura, R.2    Kitajima, T.3    Okochi, T.4    Okumura, T.5    Tsunoka, T.6
  • 35
    • 27744518040 scopus 로고    scopus 로고
    • FoxO1 protects against pancreatic beta cell failure through NeuroD and MafA induction
    • Kitamura, Y.I., Kitamura, T., Kruse, J.-P., Raum, J.C., Stein, R., Gu, W. et al., FoxO1 protects against pancreatic beta cell failure through NeuroD and MafA induction. Cell Metab. 2 (2005), 153–163.
    • (2005) Cell Metab. , vol.2 , pp. 153-163
    • Kitamura, Y.I.1    Kitamura, T.2    Kruse, J.-P.3    Raum, J.C.4    Stein, R.5    Gu, W.6
  • 36
    • 84883816971 scopus 로고    scopus 로고
    • Sleep architecture variation: a mediator of metabolic disturbance in individuals with major depressive disorder
    • Kudlow, P.A., Cha, D.S., Lam, R.W., McIntyre, R.S., Sleep architecture variation: a mediator of metabolic disturbance in individuals with major depressive disorder. Sleep Med. 14 (2013), 943–949.
    • (2013) Sleep Med. , vol.14 , pp. 943-949
    • Kudlow, P.A.1    Cha, D.S.2    Lam, R.W.3    McIntyre, R.S.4
  • 37
    • 79955661493 scopus 로고    scopus 로고
    • Hepatic overexpression of SIRT1 in mice attenuates endoplasmic reticulum stress and insulin resistance in the liver
    • Li, Y., Xu, S., Giles, A., Nakamura, K., Lee, J.W., Hou, X. et al., Hepatic overexpression of SIRT1 in mice attenuates endoplasmic reticulum stress and insulin resistance in the liver. FASEB J. 25 (2011), 1664–1679.
    • (2011) FASEB J. , vol.25 , pp. 1664-1679
    • Li, Y.1    Xu, S.2    Giles, A.3    Nakamura, K.4    Lee, J.W.5    Hou, X.6
  • 38
    • 84871431259 scopus 로고    scopus 로고
    • A pilot randomized, placebo controlled, double blind phase I trial of the novel SIRT1 activator SRT2104 in elderly volunteers
    • Libri, V., Brown, A.P., Gambarota, G., Haddad, J., Shields, G.S., Dawes, H. et al., A pilot randomized, placebo controlled, double blind phase I trial of the novel SIRT1 activator SRT2104 in elderly volunteers. PLoS One, 7, 2012, e51395.
    • (2012) PLoS One , vol.7
    • Libri, V.1    Brown, A.P.2    Gambarota, G.3    Haddad, J.4    Shields, G.S.5    Dawes, H.6
  • 39
    • 84923022358 scopus 로고    scopus 로고
    • SIRT2 is involved in the modulation of depressive behaviors
    • Liu, R., Dang, W., Du, Y., Zhou, Q., Jiao, K., Liu, Z., SIRT2 is involved in the modulation of depressive behaviors. Sci. Rep., 5, 2015, 8415.
    • (2015) Sci. Rep. , vol.5 , pp. 8415
    • Liu, R.1    Dang, W.2    Du, Y.3    Zhou, Q.4    Jiao, K.5    Liu, Z.6
  • 40
    • 85041604209 scopus 로고    scopus 로고
    • Functional genetic variants within the SIRT2 gene promoter in type 2 diabetes mellitus
    • Liu, T., Yang, W., Pang, S., Yu, S., Yan, B., Functional genetic variants within the SIRT2 gene promoter in type 2 diabetes mellitus. Diabetes Res. Clin. Pract. 137 (2018), 200–207.
    • (2018) Diabetes Res. Clin. Pract. , vol.137 , pp. 200-207
    • Liu, T.1    Yang, W.2    Pang, S.3    Yu, S.4    Yan, B.5
  • 41
    • 84991298991 scopus 로고    scopus 로고
    • Down-regulation of SIRT1 gene expression in major depressive disorder
    • Luo, X.-J., Zhang, C., Down-regulation of SIRT1 gene expression in major depressive disorder. Am. J. Psychiatry, 173, 2016, 1046.
    • (2016) Am. J. Psychiatry , vol.173 , pp. 1046
    • Luo, X.-J.1    Zhang, C.2
  • 42
    • 85006043642 scopus 로고    scopus 로고
    • Cognitive dysfunction in major depression and bipolar disorder: assessment and treatment options
    • MacQueen, G.M., Memedovich, K.A., Cognitive dysfunction in major depression and bipolar disorder: assessment and treatment options. Psychiatry Clin. Neurosci. 71 (2017), 18–27.
    • (2017) Psychiatry Clin. Neurosci. , vol.71 , pp. 18-27
    • MacQueen, G.M.1    Memedovich, K.A.2
  • 43
    • 84878757053 scopus 로고    scopus 로고
    • Cognitive deficits and functional outcomes in major depressive disorder: determinants, substrates, and treatment interventions
    • McIntyre, R.S., Cha, D.S., Soczynska, J.K., Woldeyohannes, H.O., Gallaugher, L.A., Kudlow, P. et al., Cognitive deficits and functional outcomes in major depressive disorder: determinants, substrates, and treatment interventions. Depress. Anxiety. 30 (2013), 515–527.
    • (2013) Depress. Anxiety. , vol.30 , pp. 515-527
    • McIntyre, R.S.1    Cha, D.S.2    Soczynska, J.K.3    Woldeyohannes, H.O.4    Gallaugher, L.A.5    Kudlow, P.6
  • 44
    • 84940597033 scopus 로고    scopus 로고
    • The prevalence, measurement, and treatment of the cognitive dimension/domain in major depressive disorder
    • McIntyre, R.S., Xiao, H.X., Syeda, K., Vinberg, M., Carvalho, A.F., Mansur, R.B. et al., The prevalence, measurement, and treatment of the cognitive dimension/domain in major depressive disorder. CNS Drugs. 29 (2015), 577–589.
    • (2015) CNS Drugs. , vol.29 , pp. 577-589
    • McIntyre, R.S.1    Xiao, H.X.2    Syeda, K.3    Vinberg, M.4    Carvalho, A.F.5    Mansur, R.B.6
  • 45
    • 77954855825 scopus 로고    scopus 로고
    • SIRT1 is essential for normal cognitive function and synaptic plasticity
    • Michán, S., Li, Y., Chou, M.M.-H., Parrella, E., Ge, H., Long, J.M. et al., SIRT1 is essential for normal cognitive function and synaptic plasticity. J. Neurosci. 30 (2010), 9695–9707.
    • (2010) J. Neurosci. , vol.30 , pp. 9695-9707
    • Michán, S.1    Li, Y.2    Chou, M.M.-H.3    Parrella, E.4    Ge, H.5    Long, J.M.6
  • 47
    • 47549088250 scopus 로고    scopus 로고
    • The NAD+-dependent deacetylase SIRT1 modulates CLOCK-mediated chromatin remodeling and circadian control
    • Nakahata, Y., Kaluzova, M., Grimaldi, B., Sahar, S., Hirayama, J., Chen, D. et al., The NAD+-dependent deacetylase SIRT1 modulates CLOCK-mediated chromatin remodeling and circadian control. Cell 134 (2008), 329–340.
    • (2008) Cell , vol.134 , pp. 329-340
    • Nakahata, Y.1    Kaluzova, M.2    Grimaldi, B.3    Sahar, S.4    Hirayama, J.5    Chen, D.6
  • 49
    • 84978933093 scopus 로고    scopus 로고
    • Association between Sirtuin 1 gene rs10997870 polymorphism and suicide behaviors in bipolar disorder
    • Nivoli, A., Porcelli, S., Albani, D., Forloni, G., Fusco, F., Colom, F. et al., Association between Sirtuin 1 gene rs10997870 polymorphism and suicide behaviors in bipolar disorder. Neuropsychobiology 74 (2016), 1–7.
    • (2016) Neuropsychobiology , vol.74 , pp. 1-7
    • Nivoli, A.1    Porcelli, S.2    Albani, D.3    Forloni, G.4    Fusco, F.5    Colom, F.6
  • 51
    • 45849121349 scopus 로고    scopus 로고
    • Modulation of SIRT1 expression in different neurodegenerative models and human pathologies
    • Pallàs, M., Pizarro, J.G., Gutierrez-Cuesta, J., Crespo-Biel, N., Alvira, D., Tajes, M. et al., Modulation of SIRT1 expression in different neurodegenerative models and human pathologies. Neuroscience 154 (2008), 1388–1397.
    • (2008) Neuroscience , vol.154 , pp. 1388-1397
    • Pallàs, M.1    Pizarro, J.G.2    Gutierrez-Cuesta, J.3    Crespo-Biel, N.4    Alvira, D.5    Tajes, M.6
  • 52
    • 34247634564 scopus 로고    scopus 로고
    • Three circadian clock genes Per2, Arntl, and Npas2 contribute to winter depression
    • Partonen, T., Treutlein, J., Alpman, A., Frank, J., Johansson, C., Depner, M. et al., Three circadian clock genes Per2, Arntl, and Npas2 contribute to winter depression. Ann. Med. 39 (2007), 229–238.
    • (2007) Ann. Med. , vol.39 , pp. 229-238
    • Partonen, T.1    Treutlein, J.2    Alpman, A.3    Frank, J.4    Johansson, C.5    Depner, M.6
  • 54
    • 84890565755 scopus 로고    scopus 로고
    • Association between Sirtuin 2 gene rs10410544 polymorphism and depression in Alzheimer's disease in two independent European samples
    • Porcelli, S., Salfi, R., Politis, A., Atti, A.R., Albani, D., Chierchia, A. et al., Association between Sirtuin 2 gene rs10410544 polymorphism and depression in Alzheimer's disease in two independent European samples. J. Neural Transm. 120 (2013), 1709–1715.
    • (2013) J. Neural Transm. , vol.120 , pp. 1709-1715
    • Porcelli, S.1    Salfi, R.2    Politis, A.3    Atti, A.R.4    Albani, D.5    Chierchia, A.6
  • 55
    • 78649521247 scopus 로고    scopus 로고
    • Calorie restriction reduces oxidative stress by SIRT3-mediated SOD2 activation
    • Qiu, X., Brown, K., Hirschey, M.D., Verdin, E., Chen, D., Calorie restriction reduces oxidative stress by SIRT3-mediated SOD2 activation. Cell Metab. 12 (2010), 662–667.
    • (2010) Cell Metab. , vol.12 , pp. 662-667
    • Qiu, X.1    Brown, K.2    Hirschey, M.D.3    Verdin, E.4    Chen, D.5
  • 56
    • 84856234396 scopus 로고    scopus 로고
    • Age-associated decrease of SIRT1 expression in rat hippocampus: prevention by late onset caloric restriction
    • Quintas, A., de Solís, A.J., Díez-Guerra, F.J., Carrascosa, J.M., Bogónez, E., Age-associated decrease of SIRT1 expression in rat hippocampus: prevention by late onset caloric restriction. Exp. Gerontol. 47 (2012), 198–201.
    • (2012) Exp. Gerontol. , vol.47 , pp. 198-201
    • Quintas, A.1    de Solís, A.J.2    Díez-Guerra, F.J.3    Carrascosa, J.M.4    Bogónez, E.5
  • 57
    • 54049158932 scopus 로고    scopus 로고
    • Brain SIRT1: anatomical distribution and regulation by energy availability
    • Ramadori, G., Lee, C.E., Bookout, A.L., Lee, S., Williams, K.W., Anderson, J. et al., Brain SIRT1: anatomical distribution and regulation by energy availability. J. Neurosci. 28 (2008), 9989–9996.
    • (2008) J. Neurosci. , vol.28 , pp. 9989-9996
    • Ramadori, G.1    Lee, C.E.2    Bookout, A.L.3    Lee, S.4    Williams, K.W.5    Anderson, J.6
  • 58
    • 85040331461 scopus 로고    scopus 로고
    • SIRT3 activator Honokiol attenuates β-amyloid by modulating amyloidogenic pathway
    • Ramesh, S., Govindarajulu, M., Lynd, T., Briggs, G., Adamek, D., Jones, E. et al., SIRT3 activator Honokiol attenuates β-amyloid by modulating amyloidogenic pathway. PLoS One, 13, 2018, e0190350.
    • (2018) PLoS One , vol.13
    • Ramesh, S.1    Govindarajulu, M.2    Lynd, T.3    Briggs, G.4    Adamek, D.5    Jones, E.6
  • 59
    • 84946607216 scopus 로고    scopus 로고
    • Sirtuin 3 regulates Foxo3a-mediated antioxidant pathway in microglia
    • Rangarajan, P., Karthikeyan, A., Lu, J., Ling, E.-A., Dheen, S.T., Sirtuin 3 regulates Foxo3a-mediated antioxidant pathway in microglia. Neuroscience 311 (2015), 398–414.
    • (2015) Neuroscience , vol.311 , pp. 398-414
    • Rangarajan, P.1    Karthikeyan, A.2    Lu, J.3    Ling, E.-A.4    Dheen, S.T.5
  • 61
    • 33745889628 scopus 로고    scopus 로고
    • Reversible lysine acetylation controls the activity of the mitochondrial enzyme acetyl-CoA synthetase 2
    • Schwer, B., Bunkenborg, J., Verdin, R.O., Andersen, J.S., Verdin, E., Reversible lysine acetylation controls the activity of the mitochondrial enzyme acetyl-CoA synthetase 2. Proc. Natl. Acad. Sci. U. S. A. 103 (2006), 10224–10229.
    • (2006) Proc. Natl. Acad. Sci. U. S. A. , vol.103 , pp. 10224-10229
    • Schwer, B.1    Bunkenborg, J.2    Verdin, R.O.3    Andersen, J.S.4    Verdin, E.5
  • 62
    • 78649509214 scopus 로고    scopus 로고
    • SIRT3 deacetylates mitochondrial 3-hydroxy-3-methylglutaryl CoA synthase 2 and regulates ketone body production
    • Shimazu, T., Hirschey, M.D., Hua, L., Dittenhafer-Reed, K.E., Schwer, B., Lombard, D.B. et al., SIRT3 deacetylates mitochondrial 3-hydroxy-3-methylglutaryl CoA synthase 2 and regulates ketone body production. Cell Metab. 12 (2010), 654–661.
    • (2010) Cell Metab. , vol.12 , pp. 654-661
    • Shimazu, T.1    Hirschey, M.D.2    Hua, L.3    Dittenhafer-Reed, K.E.4    Schwer, B.5    Lombard, D.B.6
  • 63
    • 78651468722 scopus 로고    scopus 로고
    • Sirt3 mediates reduction of oxidative damage and prevention of age-related hearing loss under caloric restriction
    • Someya, S., Yu, W., Hallows, W.C., Xu, J., Vann, J.M., Leeuwenburgh, C. et al., Sirt3 mediates reduction of oxidative damage and prevention of age-related hearing loss under caloric restriction. Cell 143 (2010), 802–812.
    • (2010) Cell , vol.143 , pp. 802-812
    • Someya, S.1    Yu, W.2    Hallows, W.C.3    Xu, J.4    Vann, J.M.5    Leeuwenburgh, C.6
  • 64
    • 34548857700 scopus 로고    scopus 로고
    • SIRT1 improves insulin sensitivity under insulin-resistant conditions by repressing PTP1B
    • Sun, C., Zhang, F., Ge, X., Yan, T., Chen, X., Shi, X. et al., SIRT1 improves insulin sensitivity under insulin-resistant conditions by repressing PTP1B. Cell Metab. 6 (2007), 307–319.
    • (2007) Cell Metab. , vol.6 , pp. 307-319
    • Sun, C.1    Zhang, F.2    Ge, X.3    Yan, T.4    Chen, X.5    Shi, X.6
  • 66
    • 85009154389 scopus 로고    scopus 로고
    • Resveratrol ameliorates spatial learning memory impairment induced by Aβ 1—42 in rats
    • Wang, R., Zhang, Y., Li, J., Zhang, C., Resveratrol ameliorates spatial learning memory impairment induced by Aβ 1—42 in rats. Neuroscience 344 (2017), 39–47.
    • (2017) Neuroscience , vol.344 , pp. 39-47
    • Wang, R.1    Zhang, Y.2    Li, J.3    Zhang, C.4
  • 67
    • 34248219265 scopus 로고    scopus 로고
    • Corrigendum: Sirtuin activators mimic caloric restriction and delay ageing in metazoans
    • Wood, J.G., Rogina, B., Lavu, S., Howitz, K., Helfand, S.L., Tatar, M. et al., Corrigendum: Sirtuin activators mimic caloric restriction and delay ageing in metazoans. Nature, 431, 2004, 107.
    • (2004) Nature , vol.431 , pp. 107
    • Wood, J.G.1    Rogina, B.2    Lavu, S.3    Howitz, K.4    Helfand, S.L.5    Tatar, M.6
  • 68
    • 61749095297 scopus 로고    scopus 로고
    • SIRT1 exerts anti-inflammatory effects and improves insulin sensitivity in adipocytes
    • Yoshizaki, T., Milne, J.C., Imamura, T., Schenk, S., Sonoda, N., Babendure, J.L. et al., SIRT1 exerts anti-inflammatory effects and improves insulin sensitivity in adipocytes. Mol. Cell. Biol. 29 (2009), 1363–1374.
    • (2009) Mol. Cell. Biol. , vol.29 , pp. 1363-1374
    • Yoshizaki, T.1    Milne, J.C.2    Imamura, T.3    Schenk, S.4    Sonoda, N.5    Babendure, J.L.6
  • 69
    • 36348974168 scopus 로고    scopus 로고
    • The direct involvement of SirT1 in insulin-induced insulin receptor substrate-2 tyrosine phosphorylation
    • Zhang, J., The direct involvement of SirT1 in insulin-induced insulin receptor substrate-2 tyrosine phosphorylation. J. Biol. Chem. 282 (2007), 34356–34364.
    • (2007) J. Biol. Chem. , vol.282 , pp. 34356-34364
    • Zhang, J.1
  • 70
    • 84979276952 scopus 로고    scopus 로고
    • Sirtuin-3 (SIRT3) protects pancreatic β-cells from endoplasmic reticulum (ER) stress-induced apoptosis and dysfunction
    • Zhang, H.-H., Ma, X.-J., Wu, L.-N., Zhao, Y.-Y., Zhang, P.-Y., Zhang, Y.-H. et al., Sirtuin-3 (SIRT3) protects pancreatic β-cells from endoplasmic reticulum (ER) stress-induced apoptosis and dysfunction. Mol. Cell. Biochem. 420 (2016), 95–106.
    • (2016) Mol. Cell. Biochem. , vol.420 , pp. 95-106
    • Zhang, H.-H.1    Ma, X.-J.2    Wu, L.-N.3    Zhao, Y.-Y.4    Zhang, P.-Y.5    Zhang, Y.-H.6


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