SIRT1 mediates depression-like behaviors in the nucleus accumbens

Journal of Neuroscience

Volumn 36, Issue 32, 2016, Pages 8441-8452

  Kim, Hee Dae ^a   Hesterman, Jennifer ^a   Call, Tanessa ^a   Magazu, Samantha ^a   Keeley, Elizabeth ^b   Armenta, Kristyna ^a   Kronman, Hope ^b   Neve, Rachael L ^c   Nestler, Eric J ^b   Ferguson, Deveroux ^a  

^a UNIVERSITY OF ARIZONA COLLEGE OF MEDICINE   (United States)

^b MOUNT SINAI SCHOOL OF MEDICINE   (United States)

^c MASSACHUSETTS INSTITUTE OF TECHNOLOGY   (United States)

Author keywords

Anxiety; Cell type specific; Depression; Epigenetic; Stress; Striatum

Indexed keywords

RESVERATROL; SELISISTAT; SIRTUIN 1; 6-CHLORO-2,3,4,9-TETRAHYDRO-1H-CARBAZOLE-1-CARBOXAMIDE; ANTIDEPRESSANT AGENT; CARBAZOLE DERIVATIVE; DOPAMINE 1 RECEPTOR; DOPAMINE 2 RECEPTOR; SIRT1 PROTEIN, MOUSE;

ANIMAL TISSUE; ANXIETY; ARTICLE; CHROMATIN IMMUNOPRECIPITATION; CONTROLLED STUDY; DEPRESSION; ELEVATED PLUS MAZE TEST; ENZYME ACTIVITY; EXPERIMENTAL BEHAVIORAL TEST; FLUORESCENCE; FORCED SWIM TEST; IMMUNOHISTOCHEMISTRY; MALE; MOUSE; NONHUMAN; NUCLEUS ACCUMBENS; OPEN FIELD TEST; OSMOTIC MINIPUMP; POLYACRYLAMIDE GEL ELECTROPHORESIS; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; SUCROSE PREFERENCE TEST; WESTERN BLOTTING; ANIMAL; ANTAGONISTS AND INHIBITORS; C57BL MOUSE; COMPLICATION; CYTOLOGY; DISEASE MODEL; DOPAMINERGIC NERVE CELL; DRUG DELIVERY SYSTEM; DRUG EFFECTS; EXPLORATORY BEHAVIOR; FOOD PREFERENCE; GENE EXPRESSION REGULATION; GENETICS; MAZE TEST; MENTAL STRESS; METABOLISM; PHYSIOLOGY; PSYCHOLOGY; SWIMMING; TRANSGENIC MOUSE;

ANIMALS; ANTIDEPRESSIVE AGENTS; CARBAZOLES; DEPRESSION; DISEASE MODELS, ANIMAL; DOPAMINERGIC NEURONS; DRUG DELIVERY SYSTEMS; EXPLORATORY BEHAVIOR; FOOD PREFERENCES; GENE EXPRESSION REGULATION; MALE; MAZE LEARNING; MICE; MICE, INBRED C57BL; MICE, TRANSGENIC; NUCLEUS ACCUMBENS; RECEPTORS, DOPAMINE D1; RECEPTORS, DOPAMINE D2; SIRTUIN 1; STRESS, PSYCHOLOGICAL; SWIMMING;

EID: 84981320357     PISSN: 02706474     EISSN: 15292401     Source Type: Journal    
DOI: 10.1523/JNEUROSCI.0212-16.2016     Document Type: Article

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