Down-regulation of SIRT1 gene expression in major depressive disorder

American Journal of Psychiatry

Volumn 173, Issue 10, 2016, Pages 1046-

  Luo, Xiong Jian ^a   Zhang, Chen ^a  

^a SHANGHAI JIAO TONG UNIVERSITY SCHOOL OF MEDICINE   (China)

Author keywords

[No Author keywords available]

Indexed keywords

SIRTUIN 1; SIRT1 PROTEIN, HUMAN;

CONTROLLED STUDY; DOWN REGULATION; GENE EXPRESSION REGULATION; GENETIC ASSOCIATION; GENETIC VARIABILITY; GENOME-WIDE ASSOCIATION STUDY; HUMAN; LETTER; MAJOR CLINICAL STUDY; MAJOR DEPRESSION; PATHOGENESIS; PRIORITY JOURNAL; SIRT1 GENE; GENETICS; PHYSIOLOGY;

DEPRESSIVE DISORDER, MAJOR; DOWN-REGULATION; HUMANS; SIRTUIN 1;

EID: 84991298991     PISSN: 0002953X     EISSN: 15357228     Source Type: Journal    
DOI: 10.1176/appi.ajp.2016.16040394     Document Type: Letter

References (5)

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2. CONVERGE consortium: Sparse whole-genome sequencing identifies two loci for major depressive disorder. Nature 2015; 523:588-591
3. Livak KJ, Schmittgen TD: Analysis of relative gene expression data using real-time quantitativePCRandthe 2(-Delta Delta C(T)) method. Methods 2001; 25:402-408
4. Jansen R, Penninx BW, Madar V, et al: Gene expression in major depressive disorder. Mol Psychiatry 2016; 21:339-347
5. Abe-Higuchi N, Uchida S, Yamagata H, et al: Hippocampal sirtuin 1 signaling mediates depression-like behavior. Biol Psychiatry (Epub ahead of print, Jan 30, 2016)