Caspase-8 deficiency in mouse embryos triggers chronic RIPK1-dependent activation of inflammatory genes, independently of RIPK3

Cell Death and Differentiation

Volumn 25, Issue 6, 2018, Pages 1107-1117

  Kang, Tae Bong ^a   Jeong, Ju Seong ^b   Yang, Seung Hoon ^b,c   Kovalenko, Andrew ^b   Wallach, David ^b  

^a Konkuk University   (South Korea)

^b WEIZMANN INSTITUTE OF SCIENCE   (Israel)

^c Korea Institute of Science and Technology   (South Korea)

Author keywords

[No Author keywords available]

Indexed keywords

ACUTE PHASE PROTEIN; ACUTE PHASE PROTEIN SAA3; CASPASE 8; GAMMA INTERFERON INDUCIBLE PROTEIN 10; MESSENGER RNA; PROTEIN KINASE; RANTES; RIPK1 PROTEIN KINASE; RIPK3 PROTEIN KINASE; TUMOR NECROSIS FACTOR; UNCLASSIFIED DRUG; CASP8 PROTEIN, MOUSE; RECEPTOR INTERACTING PROTEIN SERINE THREONINE KINASE; RIPK1 PROTEIN, MOUSE; RIPK3 PROTEIN, MOUSE;

ALLELE; ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CASP8 GENE; CONTROLLED STUDY; EMBRYO; ENDOTHELIUM CELL; ENZYME DEFICIENCY; FETUS; GENE; GENE ACTIVATION; GENE DELETION; GENE EXPRESSION REGULATION; INFLAMMATION; MOUSE; NECROPTOSIS; NONHUMAN; PROTEIN PHOSPHORYLATION; RIPK1 GENE; RIPK3 GENE; SIGNAL TRANSDUCTION; UPREGULATION; ANIMAL; EMBRYOLOGY; ENZYMOLOGY; GENETICS; KNOCKOUT MOUSE; MAMMALIAN EMBRYO; METABOLISM; TRANSCRIPTION INITIATION;

ANIMALS; CASPASE 8; EMBRYO, MAMMALIAN; GENE EXPRESSION REGULATION, DEVELOPMENTAL; GENE EXPRESSION REGULATION, ENZYMOLOGIC; INFLAMMATION; MICE; MICE, KNOCKOUT; RECEPTOR-INTERACTING PROTEIN SERINE-THREONINE KINASES; SIGNAL TRANSDUCTION; TRANSCRIPTIONAL ACTIVATION;

EID: 85045460511     PISSN: 13509047     EISSN: 14765403     Source Type: Journal    
DOI: 10.1038/s41418-018-0104-9     Document Type: Article

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