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Volumn 135, Issue 8, 2015, Pages 2021-2030

Upregulated RIP3 Expression Potentiates MLKL Phosphorylation-Mediated Programmed Necrosis in Toxic Epidermal Necrolysis

Author keywords

[No Author keywords available]

Indexed keywords

DABRAFENIB; MITOGEN ACTIVATED PROTEIN KINASE; MIXED LINEAGE KINASE DOMAIN LIKE PROTEIN; PEPTIDES AND PROTEINS; REACTIVE OXYGEN METABOLITE; RECEPTOR INTERACTING PROTEIN KINASE 3; UNCLASSIFIED DRUG; IMIDAZOLE DERIVATIVE; MLKL PROTEIN, HUMAN; OXIME; PROTEIN KINASE; PROTEIN KINASE INHIBITOR; RECEPTOR INTERACTING PROTEIN SERINE THREONINE KINASE; RIPK3 PROTEIN, HUMAN;

EID: 84937635416     PISSN: 0022202X     EISSN: 15231747     Source Type: Journal    
DOI: 10.1038/jid.2015.90     Document Type: Article
Times cited : (60)

References (47)
  • 1
    • 53349101050 scopus 로고    scopus 로고
    • Toxic epidermal necrolysis and Stevens-Johnson syndrome: Soluble Fas ligand involvement in the pathomechanisms of these diseases
    • Abe R (2008) Toxic epidermal necrolysis and Stevens-Johnson syndrome: soluble Fas ligand involvement in the pathomechanisms of these diseases. J Dermatol Sci 52:151-9
    • (2008) J Dermatol Sci , vol.52 , pp. 151-159
    • Abe, R.1
  • 2
    • 84893778822 scopus 로고    scopus 로고
    • Apoptotic and necroptotic cell death in cutaneous inflammation
    • e-pub ahead of print 7 April 2013
    • Bonnet MC, Bagot M, Bensussan A (2013) Apoptotic and necroptotic cell death in cutaneous inflammation. Eur J Dermatol. e-pub ahead of print 7 April 2013
    • (2013) Eur J Dermatol
    • Bonnet, M.C.1    Bagot, M.2    Bensussan, A.3
  • 3
    • 80755132824 scopus 로고    scopus 로고
    • The adaptor protein FADD protects epidermal keratinocytes from necroptosis in vivo and prevents skin inflammation
    • Bonnet MC, Preukschat D, Welz PS et al. (2011) The adaptor protein FADD protects epidermal keratinocytes from necroptosis in vivo and prevents skin inflammation. Immunity 35:572-82
    • (2011) Immunity , vol.35 , pp. 572-582
    • Bonnet, M.C.1    Preukschat, D.2    Welz, P.S.3
  • 4
    • 84893325471 scopus 로고    scopus 로고
    • Plasma membrane translocation of trimerized MLKL protein is required for TNF-induced necroptosis
    • Cai Z, Jitkaew S, Zhao J et al. (2014) Plasma membrane translocation of trimerized MLKL protein is required for TNF-induced necroptosis. Nat Cell Biol 16:55-65
    • (2014) Nat Cell Biol , vol.16 , pp. 55-65
    • Cai, Z.1    Jitkaew, S.2    Zhao, J.3
  • 5
    • 78751653979 scopus 로고    scopus 로고
    • Association of HLA-B∗1502 allele with carbamazepine-induced toxic epidermal necrolysis and Stevens-Johnson syndrome in the multi-ethnic Malaysian population
    • Chang CC, Too CL, Murad S et al. (2011) Association of HLA-B∗1502 allele with carbamazepine-induced toxic epidermal necrolysis and Stevens-Johnson syndrome in the multi-ethnic Malaysian population. Int J Dermatol 50: 221-4
    • (2011) Int J Dermatol , vol.50 , pp. 221-224
    • Chang, C.C.1    Too, C.L.2    Murad, S.3
  • 6
    • 84891739370 scopus 로고    scopus 로고
    • Translocation of mixed lineage kinase domainlike protein to plasma membrane leads to necrotic cell death
    • Chen X, Li W, Ren J et al. (2014) Translocation of mixed lineage kinase domainlike protein to plasma membrane leads to necrotic cell death. Cell Res 24: 105-21
    • (2014) Cell Res , vol.24 , pp. 105-121
    • Chen, X.1    Li, W.2    Ren, J.3
  • 7
    • 57349198641 scopus 로고    scopus 로고
    • Granulysin is a key mediator for disseminated keratinocyte death in Stevens-Johnson syndrome and toxic epidermal necrolysis
    • Chung WH, Hung SI, Yang JY et al. (2008) Granulysin is a key mediator for disseminated keratinocyte death in Stevens-Johnson syndrome and toxic epidermal necrolysis. Nat Med 14:1343-50
    • (2008) Nat Med , vol.14 , pp. 1343-1350
    • Chung, W.H.1    Hung, S.I.2    Yang, J.Y.3
  • 8
    • 67650638892 scopus 로고    scopus 로고
    • RIP Kinases at the Crossroads of Cell Death and Survival
    • Declercq W, Vanden Berghe T, Vandenabeele P (2009) RIP Kinases at the Crossroads of Cell Death and Survival. Cell 138:229-32
    • (2009) Cell , vol.138 , pp. 229-232
    • Declercq, W.1    Vanden Berghe, T.2    Vandenabeele, P.3
  • 9
    • 42249102086 scopus 로고    scopus 로고
    • Identification of RIP1 kinase as a specific cellular target of necrostatins
    • Degterev A, Hitomi J, Germscheid M et al. (2008) Identification of RIP1 kinase as a specific cellular target of necrostatins. Nat Chem Biol 4: 313-21
    • (2008) Nat Chem Biol , vol.4 , pp. 313-321
    • Degterev, A.1    Hitomi, J.2    Germscheid, M.3
  • 10
    • 84861235187 scopus 로고    scopus 로고
    • Toxic epidermal necrolysis: Review of pathogenesis and management
    • Downey A, Jackson C, Harun N et al. (2012) Toxic epidermal necrolysis: review of pathogenesis and management. J Am Acad Dermatol 66: 995-1003
    • (2012) J Am Acad Dermatol , vol.66 , pp. 995-1003
    • Downey, A.1    Jackson, C.2    Harun, N.3
  • 11
    • 79960922705 scopus 로고    scopus 로고
    • CIAPs block Ripoptosome formation, a RIP1/caspase-8 containing intracellular cell death complex differentially regulated by cFLIP isoforms
    • Feoktistova M, Geserick P, Kellert B et al. (2011) cIAPs block Ripoptosome formation, a RIP1/caspase-8 containing intracellular cell death complex differentially regulated by cFLIP isoforms. Mol Cell 43: 449-63
    • (2011) Mol Cell , vol.43 , pp. 449-463
    • Feoktistova, M.1    Geserick, P.2    Kellert, B.3
  • 12
    • 84255210700 scopus 로고    scopus 로고
    • Molecular definitions of cell death subroutines: Recommendations of the Nomenclature Committee on Cell Death 2012
    • Galluzzi L, Vitale I, Abrams JM et al. (2012) Molecular definitions of cell death subroutines: recommendations of the Nomenclature Committee on Cell Death 2012. Cell Death Differ 19:107-20
    • (2012) Cell Death Differ , vol.19 , pp. 107-120
    • Galluzzi, L.1    Vitale, I.2    Abrams, J.M.3
  • 13
    • 76149104286 scopus 로고    scopus 로고
    • Cellular IAPs inhibit a cryptic CD95-induced cell death by limiting RIP1 kinase recruitment
    • Geserick P, Hupe M, Moulin M et al. (2009) Cellular IAPs inhibit a cryptic CD95-induced cell death by limiting RIP1 kinase recruitment. J Cell Biol 187:1037-54
    • (2009) J Cell Biol , vol.187 , pp. 1037-1054
    • Geserick, P.1    Hupe, M.2    Moulin, M.3
  • 14
    • 19244366336 scopus 로고    scopus 로고
    • Treatment of severe drug reactions: Stevens-Johnson syndrome, toxic epidermal necrolysis and hypersensitivity syndrome
    • Ghislain PD, Roujeau JC (2002) Treatment of severe drug reactions: Stevens-Johnson syndrome, toxic epidermal necrolysis and hypersensitivity syndrome. Dermatol Online J 8:5
    • (2002) Dermatol Online J , vol.8 , pp. 5
    • Ghislain, P.D.1    Roujeau, J.C.2
  • 15
    • 84874263775 scopus 로고    scopus 로고
    • Necroptosis: The release of damage-associated molecular patterns and its physiological relevance
    • Kaczmarek A, Vandenabeele P, Krysko DV (2013) Necroptosis: the release of damage-associated molecular patterns and its physiological relevance. Immunity 38:209-23
    • (2013) Immunity , vol.38 , pp. 209-223
    • Kaczmarek, A.1    Vandenabeele, P.2    Krysko, D.V.3
  • 16
    • 79952811804 scopus 로고    scopus 로고
    • RIP3 mediates the embryonic lethality of caspase-8-deficient mice
    • Kaiser WJ, Upton JW, Long AB et al. (2011) RIP3 mediates the embryonic lethality of caspase-8-deficient mice. Nature 471:368-72
    • (2011) Nature , vol.471 , pp. 368-372
    • Kaiser, W.J.1    Upton, J.W.2    Long, A.B.3
  • 17
    • 14844327760 scopus 로고    scopus 로고
    • Reactive oxygen species promote TNFalpha-induced death and sustained JNK activation by inhibiting MAP kinase phosphatases
    • Kamata H, Honda S, Maeda S et al. (2005) Reactive oxygen species promote TNFalpha-induced death and sustained JNK activation by inhibiting MAP kinase phosphatases. Cell 120:649-61
    • (2005) Cell , vol.120 , pp. 649-661
    • Kamata, H.1    Honda, S.2    Maeda, S.3
  • 18
    • 61549115662 scopus 로고    scopus 로고
    • HLA-B locus in Japanese patients with anti-epileptics and allopurinol-related Stevens-Johnson syndrome and toxic epidermal necrolysis
    • Kaniwa N, Saito Y, Aihara M et al. (2008) HLA-B locus in Japanese patients with anti-epileptics and allopurinol-related Stevens-Johnson syndrome and toxic epidermal necrolysis. Pharmacogenomics 9:1617-22
    • (2008) Pharmacogenomics , vol.9 , pp. 1617-1622
    • Kaniwa, N.1    Saito, Y.2    Aihara, M.3
  • 19
    • 81055156142 scopus 로고    scopus 로고
    • Carbamazepine-induced severe cutaneous adverse reactions and HLA genotypes in Koreans
    • Kim SH, Lee KW, Song WJ et al. (2011) Carbamazepine-induced severe cutaneous adverse reactions and HLA genotypes in Koreans. Epilepsy Res 97:190-7
    • (2011) Epilepsy Res , vol.97 , pp. 190-197
    • Kim, S.H.1    Lee, K.W.2    Song, W.J.3
  • 20
    • 34249820757 scopus 로고    scopus 로고
    • TNF-induced activation of the Nox1 NADPH oxidase and its role in the induction of necrotic cell death
    • Kim YS, Morgan MJ, Choksi S et al. (2007) TNF-induced activation of the Nox1 NADPH oxidase and its role in the induction of necrotic cell death. Mol Cell 26:675-87
    • (2007) Mol Cell , vol.26 , pp. 675-687
    • Kim, Y.S.1    Morgan, M.J.2    Choksi, S.3
  • 21
    • 70350484946 scopus 로고    scopus 로고
    • Caspase-8 deficiency in epidermal keratinocytes triggers an inflammatory skin disease
    • Kovalenko A, Kim JC, Kang TB et al. (2009) Caspase-8 deficiency in epidermal keratinocytes triggers an inflammatory skin disease. J Exp Med 206: 2161-77
    • (2009) J Exp Med , vol.206 , pp. 2161-2177
    • Kovalenko, A.1    Kim, J.C.2    Kang, T.B.3
  • 22
    • 0344936731 scopus 로고    scopus 로고
    • Nitric oxide: Cytotoxicity versus cytoprotection-how, why, when, and where?
    • Kroncke KD, Fehsel K, Kolb-Bachofen V (1997) Nitric oxide: cytotoxicity versus cytoprotection-how, why, when, and where? Nitric Oxide 1:107-20
    • (1997) Nitric Oxide , vol.1 , pp. 107-120
    • Kroncke, K.D.1    Fehsel, K.2    Kolb-Bachofen, V.3
  • 23
    • 84903791583 scopus 로고    scopus 로고
    • The B-Raf(V600E) inhibitor dabrafenib selectively inhibits RIP3 and alleviates acetaminophen-induced liver injury
    • Li JX, Feng JM, Wang Y et al. (2014a) The B-Raf(V600E) inhibitor dabrafenib selectively inhibits RIP3 and alleviates acetaminophen-induced liver injury. Cell Death Dis 5:e1278
    • (2014) Cell Death Dis , vol.5 , pp. e1278
    • Li, J.X.1    Feng, J.M.2    Wang, Y.3
  • 24
    • 84903791583 scopus 로고    scopus 로고
    • The B-Raf(V600E) inhibitor dabrafenib selectively inhibits RIP3 and alleviates acetaminophen-induced liver injury
    • Li JX, Feng JM, Wang Y et al. (2014b) The B-Raf(V600E) inhibitor dabrafenib selectively inhibits RIP3 and alleviates acetaminophen-induced liver injury. Cell Death Dis 5:e1278
    • (2014) Cell Death Dis , vol.5 , pp. e1278
    • Li, J.X.1    Feng, J.M.2    Wang, Y.3
  • 25
    • 34248589506 scopus 로고    scopus 로고
    • Association between HLA-B∗1502 allele and antiepileptic drug-induced cutaneous reactions in Han Chinese
    • Man CB, Kwan P, Baum L et al. (2007) Association between HLA-B∗1502 allele and antiepileptic drug-induced cutaneous reactions in Han Chinese. Epilepsia 48:1015-8
    • (2007) Epilepsia , vol.48 , pp. 1015-1018
    • Man, C.B.1    Kwan, P.2    Baum, L.3
  • 26
    • 70450205028 scopus 로고    scopus 로고
    • Association of HLA-B∗1502 allele and carbamazepine-induced Stevens-Johnson syndrome among Indians
    • Mehta TY, Prajapati LM, Mittal B et al. (2009) Association of HLA-B∗1502 allele and carbamazepine-induced Stevens-Johnson syndrome among Indians. Indian J Dermatol Venereol Leprol 75:579-82
    • (2009) Indian J Dermatol Venereol Leprol , vol.75 , pp. 579-582
    • Mehta, T.Y.1    Prajapati, L.M.2    Mittal, B.3
  • 27
    • 55549124179 scopus 로고    scopus 로고
    • Increased soluble Fas ligand levels in patients with Stevens-Johnson syndrome and toxic epidermal necrolysis preceding skin detachment
    • Murata J, Abe R, Shimizu H (2008) Increased soluble Fas ligand levels in patients with Stevens-Johnson syndrome and toxic epidermal necrolysis preceding skin detachment. J Allergy Clin Immunol 122:992-1000
    • (2008) J Allergy Clin Immunol , vol.122 , pp. 992-1000
    • Murata, J.1    Abe, R.2    Shimizu, H.3
  • 28
    • 79952810024 scopus 로고    scopus 로고
    • Catalytic activity of the caspase-8-FLIP(L) complex inhibits RIPK3-dependent necrosis
    • Oberst A, Dillon CP, Weinlich R et al. (2011) Catalytic activity of the caspase-8-FLIP(L) complex inhibits RIPK3-dependent necrosis. Nature 471: 363-7
    • (2011) Nature , vol.471 , pp. 363-367
    • Oberst, A.1    Dillon, C.P.2    Weinlich, R.3
  • 29
    • 0029080604 scopus 로고
    • Splicing variants of the human growth hormone mRNA: Detection in pituitary, mononuclear cells and dermal fibroblasts
    • Palmetshofer A, Zechner D, Luger TA, Barta A (1995) Splicing variants of the human growth hormone mRNA: detection in pituitary, mononuclear cells and dermal fibroblasts. Mol Cell Endocrinol 113:225-34
    • (1995) Mol Cell Endocrinol , vol.113 , pp. 225-234
    • Palmetshofer, A.1    Zechner, D.2    Luger, T.A.3    Barta, A.4
  • 30
    • 84887023764 scopus 로고    scopus 로고
    • CFLIP regulates skin homeostasis and protects against TNF-induced keratinocyte apoptosis
    • Panayotova-Dimitrova D, Feoktistova M, Ploesser M et al. (2013) cFLIP regulates skin homeostasis and protects against TNF-induced keratinocyte apoptosis. Cell Rep 5:397-408
    • (2013) Cell Rep , vol.5 , pp. 397-408
    • Panayotova-Dimitrova, D.1    Feoktistova, M.2    Ploesser, M.3
  • 32
    • 84893726744 scopus 로고    scopus 로고
    • Necroptosis is active in children with inflammatory bowel disease and contributes to heighten intestinal inflammation
    • Pierdomenico M, Negroni A, Stronati L et al. (2014) Necroptosis is active in children with inflammatory bowel disease and contributes to heighten intestinal inflammation. Am J Gastroenterol 109:279-87
    • (2014) Am J Gastroenterol , vol.109 , pp. 279-287
    • Pierdomenico, M.1    Negroni, A.2    Stronati, L.3
  • 33
    • 0028304787 scopus 로고
    • Expression and function of nerve growth factor and nerve growth factor receptor on cultured keratinocytes
    • Pincelli C, Sevignani C, Manfredini R et al. (1994) Expression and function of nerve growth factor and nerve growth factor receptor on cultured keratinocytes. J Invest Dermatol 103:13-8
    • (1994) J Invest Dermatol , vol.103 , pp. 13-18
    • Pincelli, C.1    Sevignani, C.2    Manfredini, R.3
  • 34
    • 84920520695 scopus 로고    scopus 로고
    • An annexin A1-FPR1 interaction contributes to necroptosis of keratinocytes in severe cutaneous adverse drug reactions
    • Saito N, Qiao H, Yanagi T et al. (2014) An annexin A1-FPR1 interaction contributes to necroptosis of keratinocytes in severe cutaneous adverse drug reactions. Sci Transl Med 6:245ra95
    • (2014) Sci Transl Med , vol.6 , pp. 245ra95
    • Saito, N.1    Qiao, H.2    Yanagi, T.3
  • 35
    • 84880375708 scopus 로고    scopus 로고
    • Toxic epidermal necrolysis: Part I. Introduction, history, classification, clinical features, systemic manifestations, etiology, and immunopathogenesis
    • e1-13
    • Schwartz RA, McDonough PH, Lee BW (2013) Toxic epidermal necrolysis: Part I. Introduction, history, classification, clinical features, systemic manifestations, etiology, and immunopathogenesis. J Am Acad Dermatol 69: 173:e1-13
    • (2013) J Am Acad Dermatol , vol.69 , pp. 173
    • Schwartz, R.A.1    McDonough, P.H.2    Lee, B.W.3
  • 36
    • 84862907788 scopus 로고    scopus 로고
    • Mixed lineage kinase domain-like protein mediates necrosis signaling downstream of RIP3 kinase
    • Sun L, Wang H, Wang Z et al. (2012) Mixed lineage kinase domain-like protein mediates necrosis signaling downstream of RIP3 kinase. Cell 148: 213-27
    • (2012) Cell , vol.148 , pp. 213-227
    • Sun, L.1    Wang, H.2    Wang, Z.3
  • 37
    • 77957105977 scopus 로고    scopus 로고
    • Molecular mechanisms of necroptosis: An ordered cellular explosion
    • Vandenabeele P, Galluzzi L, Vanden Berghe T et al. (2010) Molecular mechanisms of necroptosis: an ordered cellular explosion. Nat Rev Mol Cell Biol 11:700-14
    • (2010) Nat Rev Mol Cell Biol , vol.11 , pp. 700-714
    • Vandenabeele, P.1    Galluzzi, L.2    Vanden Berghe, T.3
  • 40
    • 10044265209 scopus 로고    scopus 로고
    • JNK potentiates TNF-stimulated necrosis by increasing the production of cytotoxic reactive oxygen species
    • Ventura JJ, Cogswell P, Flavell RA et al. (2004) JNK potentiates TNF-stimulated necrosis by increasing the production of cytotoxic reactive oxygen species. Genes Dev 18:2905-15
    • (2004) Genes Dev , vol.18 , pp. 2905-2915
    • Ventura, J.J.1    Cogswell, P.2    Flavell, R.A.3
  • 41
    • 84872597649 scopus 로고    scopus 로고
    • TNF-alpha and IFN-gamma are potential inducers of Fas-mediated keratinocyte apoptosis through activation of inducible nitric oxide synthase in toxic epidermal necrolysis
    • Viard-Leveugle I, Gaide O, Jankovic D et al. (2013) TNF-alpha and IFN-gamma are potential inducers of Fas-mediated keratinocyte apoptosis through activation of inducible nitric oxide synthase in toxic epidermal necrolysis. J Invest Dermatol 133:489-98
    • (2013) J Invest Dermatol , vol.133 , pp. 489-498
    • Viard-Leveugle, I.1    Gaide, O.2    Jankovic, D.3
  • 42
    • 84898027331 scopus 로고    scopus 로고
    • Mixed lineage kinase domain-like protein MLKL causes necrotic membrane disruption upon phosphorylation by RIP3
    • Wang HY, Sun LM, Su LJ et al. (2014) Mixed lineage kinase domain-like protein MLKL causes necrotic membrane disruption upon phosphorylation by RIP3. Mol Cell 54:133-46
    • (2014) Mol Cell , vol.54 , pp. 133-146
    • Wang, H.Y.1    Sun, L.M.2    Su, L.J.3
  • 43
    • 84862776700 scopus 로고    scopus 로고
    • Direct interaction between HLA-B and carbamazepine activates T cells in patients with Stevens-Johnson syndrome
    • Wei CY, Chung WH, Huang HW et al. (2012) Direct interaction between HLA-B and carbamazepine activates T cells in patients with Stevens-Johnson syndrome. J Allergy Clin Immunol 129:1562-9
    • (2012) J Allergy Clin Immunol , vol.129 , pp. 1562-1569
    • Wei, C.Y.1    Chung, W.H.2    Huang, H.W.3
  • 44
    • 84861195802 scopus 로고    scopus 로고
    • Necroptosis: An emerging form of programmed cell death
    • Wu W, Liu P, Li J (2012) Necroptosis: an emerging form of programmed cell death. Crit Rev Oncol Hematol 82:249-58
    • (2012) Crit Rev Oncol Hematol , vol.82 , pp. 249-258
    • Wu, W.1    Liu, P.2    Li, J.3
  • 45
    • 78650175369 scopus 로고    scopus 로고
    • ZVAD-induced necroptosis in L929 cells depends on autocrine production of TNFalpha mediated by the PKC-MAPKs-AP-1 pathway
    • Wu YT, Tan HL, Huang Q et al. (2011) zVAD-induced necroptosis in L929 cells depends on autocrine production of TNFalpha mediated by the PKC-MAPKs-AP-1 pathway. Cell Death Differ 18:26-37
    • (2011) Cell Death Differ , vol.18 , pp. 26-37
    • Wu, Y.T.1    Tan, H.L.2    Huang, Q.3
  • 46
    • 79952780505 scopus 로고    scopus 로고
    • Functional complementation between FADD and RIP1 in embryos and lymphocytes
    • Zhang H, Zhou X, McQuade T et al. (2011) Functional complementation between FADD and RIP1 in embryos and lymphocytes. Nature 471:373-6
    • (2011) Nature , vol.471 , pp. 373-376
    • Zhang, H.1    Zhou, X.2    McQuade, T.3
  • 47
    • 84859467770 scopus 로고    scopus 로고
    • Mixed lineage kinase domain-like is a key receptor interacting protein 3 downstream component of TNF-induced necrosis
    • Zhao J, Jitkaew S, Cai Z et al. (2012) Mixed lineage kinase domain-like is a key receptor interacting protein 3 downstream component of TNF-induced necrosis. Proc Natl Acad Sci USA 109:5322-7
    • (2012) Proc Natl Acad Sci USA , vol.109 , pp. 5322-5327
    • Zhao, J.1    Jitkaew, S.2    Cai, Z.3


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