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Volumn 2017, Issue , 2017, Pages

Potential role of exosomes in mending a broken heart: Nanoshuttles propelling future clinical therapeutics forward

Author keywords

[No Author keywords available]

Indexed keywords

MICRORNA; NANOPARTICLE; NANOSHUTTLE; PROTEIN; UNCLASSIFIED DRUG;

EID: 85042583457     PISSN: None     EISSN: 16879678     Source Type: Journal    
DOI: 10.1155/2017/5785436     Document Type: Review
Times cited : (42)

References (128)
  • 1
    • 85029007717 scopus 로고    scopus 로고
    • Heart disease and stroke statistics-2017 update: A report from the American Heart Association
    • E. J. Benjamin, M. J. Blaha, S. E. Chiuve et al., "Heart disease and stroke statistics-2017 update: a report from the American Heart Association, " Circulation, vol. 135, no. 10, pp. e146-e603, 2017.
    • (2017) Circulation , vol.135 , Issue.10 , pp. e146-e603
    • Benjamin, E.J.1    Blaha, M.J.2    Chiuve, S.E.3
  • 4
    • 0033106384 scopus 로고    scopus 로고
    • Cardiomyocytes can be generated from marrow stromal cells in vitro
    • S. Makino, K. Fukuda, S. Miyoshi et al., "Cardiomyocytes can be generated from marrow stromal cells in vitro, " The Journal of Clinical Investigation, vol. 103, no. 5, pp. 697-705, 1999.
    • (1999) The Journal of Clinical Investigation , vol.103 , Issue.5 , pp. 697-705
    • Makino, S.1    Fukuda, K.2    Miyoshi, S.3
  • 5
    • 3042856796 scopus 로고    scopus 로고
    • Mesenchymal stem cells from adult human bone marrow differentiate into a cardiomyocyte phenotype in vitro
    • W. Xu, X. Zhang, H. Qian et al., "Mesenchymal stem cells from adult human bone marrow differentiate into a cardiomyocyte phenotype in vitro, " Experimental Biology and Medicine, vol. 229, no. 7, pp. 623-631, 2004.
    • (2004) Experimental Biology and Medicine , vol.229 , Issue.7 , pp. 623-631
    • Xu, W.1    Zhang, X.2    Qian, H.3
  • 6
    • 0033515827 scopus 로고    scopus 로고
    • Multilineage potential of adult human mesenchymal stem cells
    • M. F. Pittenger, A. M. Mackay, S. C. Beck et al., "Multilineage potential of adult human mesenchymal stem cells, " Science, vol. 284, no. 5411, pp. 143-147, 1999.
    • (1999) Science , vol.284 , Issue.5411 , pp. 143-147
    • Pittenger, M.F.1    Mackay, A.M.2    Beck, S.C.3
  • 7
    • 33747195353 scopus 로고    scopus 로고
    • Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors
    • K. Takahashi and S. Yamanaka, "Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors, " Cell, vol. 126, no. 4, pp. 663-676, 2006.
    • (2006) Cell , vol.126 , Issue.4 , pp. 663-676
    • Takahashi, K.1    Yamanaka, S.2
  • 8
    • 61949300076 scopus 로고    scopus 로고
    • Functional cardiomyocytes derived from human induced pluripotent stem cells
    • J. Zhang, G. F. Wilson, A. G. Soerens et al., "Functional cardiomyocytes derived from human induced pluripotent stem cells, " Circulation Research, vol. 104, no. 4, pp. e30-e41, 2009.
    • (2009) Circulation Research , vol.104 , Issue.4 , pp. e30-e41
    • Zhang, J.1    Wilson, G.F.2    Soerens, A.G.3
  • 9
    • 84864386301 scopus 로고    scopus 로고
    • Human versus porcine mesenchymal stromal cells: Phenotype, differentiation potential, immunomodulation and cardiac improvement after transplantation
    • W. A. Noort, M. I. Oerlemans, H. Rozemuller et al., "Human versus porcine mesenchymal stromal cells: phenotype, differentiation potential, immunomodulation and cardiac improvement after transplantation, " Journal of Cellular and Molecular Medicine, vol. 16, no. 8, pp. 1827-1839, 2012.
    • (2012) Journal of Cellular and Molecular Medicine , vol.16 , Issue.8 , pp. 1827-1839
    • Noort, W.A.1    Oerlemans, M.I.2    Rozemuller, H.3
  • 10
    • 84868135415 scopus 로고    scopus 로고
    • Transendocardial cell injection is not superior to intracoronary infusion in a porcine model of ischaemic cardiomyopathy: A study on delivery efficiency
    • T. I. van der Spoel, K. R. Vrijsen, S. Koudstaal et al., "Transendocardial cell injection is not superior to intracoronary infusion in a porcine model of ischaemic cardiomyopathy: a study on delivery efficiency, " Journal of Cellular and Molecular Medicine, vol. 16, no. 11, pp. 2768-2776, 2012.
    • (2012) Journal of Cellular and Molecular Medicine , vol.16 , Issue.11 , pp. 2768-2776
    • Vander Spoel, T.I.1    Vrijsen, K.R.2    Koudstaal, S.3
  • 11
    • 84863113271 scopus 로고    scopus 로고
    • Cardiomyogenic differentiation-independent improvement of cardiac function by human cardiomyocyte progenitor cell injection in ischaemic mouse hearts
    • M. C. den Haan, R. W. Grauss, A. M. Smits et al., "Cardiomyogenic differentiation-independent improvement of cardiac function by human cardiomyocyte progenitor cell injection in ischaemic mouse hearts, " Journal of Cellular and Molecular Medicine, vol. 16, no. 7, pp. 1508-1521, 2012.
    • (2012) Journal of Cellular and Molecular Medicine , vol.16 , Issue.7 , pp. 1508-1521
    • Den Haan, M.C.1    Grauss, R.W.2    Smits, A.M.3
  • 12
    • 84955357177 scopus 로고    scopus 로고
    • The current landscape of the mesenchymal stromal cell secretome: A new paradigm for cell-free regeneration
    • V. B. Konala, M. K. Mamidi, R. Bhonde, A. K. Das, R. Pochampally, and R. Pal, "The current landscape of the mesenchymal stromal cell secretome: a new paradigm for cell-free regeneration, " Cytotherapy, vol. 18, no. 1, pp. 13-24, 2016.
    • (2016) Cytotherapy , vol.18 , Issue.1 , pp. 13-24
    • Konala, V.B.1    Mamidi, M.K.2    Bhonde, R.3    Das, A.K.4    Pochampally, R.5    Pal, R.6
  • 13
    • 84949462740 scopus 로고    scopus 로고
    • Acellular approaches for regenerative medicine: On the verge of clinical trials with extracellular membrane vesicles?
    • A. Fuster-Matanzo, F. Gessler, T. Leonardi, N. Iraci, and S. Pluchino, "Acellular approaches for regenerative medicine: on the verge of clinical trials with extracellular membrane vesicles?, " Stem Cell Research & Therapy, vol. 6, p. 227, 2015.
    • (2015) Stem Cell Research & Therapy , vol.6 , pp. 227
    • Fuster-Matanzo, A.1    Gessler, F.2    Leonardi, T.3    Iraci, N.4    Pluchino, S.5
  • 14
    • 84975818569 scopus 로고    scopus 로고
    • The biological basis for cardiac repair after myocardial infarction: From inflammation to fibrosis
    • S. D. Prabhu and N. G. Frangogiannis, "The biological basis for cardiac repair after myocardial infarction: from inflammation to fibrosis, " Circulation Research, vol. 119, no. 1, pp. 91-112, 2016.
    • (2016) Circulation Research , vol.119 , Issue.1 , pp. 91-112
    • Prabhu, S.D.1    Frangogiannis, N.G.2
  • 15
    • 84930540275 scopus 로고    scopus 로고
    • Proteomics of extracellular vesicles: Exosomes and ectosomes
    • D. S. Choi, D. K. Kim, Y. K. Kim, and Y. S. Gho, "Proteomics of extracellular vesicles: exosomes and ectosomes, " Mass Spectrometry Reviews, vol. 34, no. 4, pp. 474-490, 2015.
    • (2015) Mass Spectrometry Reviews , vol.34 , Issue.4 , pp. 474-490
    • Choi, D.S.1    Kim, D.K.2    Kim, Y.K.3    Gho, Y.S.4
  • 17
    • 84907550287 scopus 로고    scopus 로고
    • Long non-coding RNAs with low expression levels in cells are enriched in secreted exosomes
    • U. Gezer, E. Özgür, M. Cetinkaya, M. Isin, and N. Dalay, "Long non-coding RNAs with low expression levels in cells are enriched in secreted exosomes, " Cell Biology International, vol. 38, no. 9, pp. 1076-1079, 2014.
    • (2014) Cell Biology International , vol.38 , Issue.9 , pp. 1076-1079
    • Gezer, U.1    Özgür, E.2    Cetinkaya, M.3    Isin, M.4    Dalay, N.5
  • 18
    • 84964284515 scopus 로고    scopus 로고
    • Long non-coding RNAs harboring miRNA seed regions are enriched in prostate cancer exosomes
    • article 24922
    • A. Ahadi, S. Brennan, P. J. Kennedy, G. Hutvagner, and N. Tran, "Long non-coding RNAs harboring miRNA seed regions are enriched in prostate cancer exosomes, " Scientific Reports, vol. 6, article 24922, 2016.
    • (2016) Scientific Reports , vol.6
    • Ahadi, A.1    Brennan, S.2    Kennedy, P.J.3    Hutvagner, G.4    Tran, N.5
  • 19
    • 84979258371 scopus 로고    scopus 로고
    • Exosome-mediated targeted delivery of miRNAs
    • S. Ohno and M. Kuroda, "Exosome-mediated targeted delivery of miRNAs, " Methods in Molecular Biology, vol. 1448, pp. 261-270, 2016.
    • (2016) Methods in Molecular Biology , vol.1448 , pp. 261-270
    • Ohno, S.1    Kuroda, M.2
  • 20
    • 85016448020 scopus 로고    scopus 로고
    • Minimal experimental requirements for definition of extracellular vesicles and their functions: A position statement from the International Society for Extracellular Vesicles
    • article 26913
    • J. Lotvall, A. F. Hill, F. Hochberg et al., "Minimal experimental requirements for definition of extracellular vesicles and their functions: a position statement from the International Society for Extracellular Vesicles, " Journal of Extracellular Vesicles, vol. 3, article 26913, 2014.
    • (2014) Journal of Extracellular Vesicles , vol.3
    • Lotvall, J.1    Hill, A.F.2    Hochberg, F.3
  • 21
    • 79960096964 scopus 로고    scopus 로고
    • Exosomes: Secreted vesicles and intercellular communications
    • C. Thery, "Exosomes: secreted vesicles and intercellular communications, " F1000 Biology Reports, vol. 3, p. 15, 2011.
    • (2011) F1000 Biology Reports , vol.3 , pp. 15
    • Thery, C.1
  • 23
    • 85013222187 scopus 로고    scopus 로고
    • Standardization of sample collection, isolation and analysis methods in extracellular vesicle research
    • K. W. Witwer, E. I. Buzás, L. T. Bemis et al., "Standardization of sample collection, isolation and analysis methods in extracellular vesicle research, " Journal of Extracellular Vesicles, vol. 2, 2013.
    • (2013) Journal of Extracellular Vesicles , vol.2
    • Witwer, K.W.1    Buzás, E.I.2    Bemis, L.T.3
  • 24
    • 68849129712 scopus 로고    scopus 로고
    • Membrane vesicles as conveyors of immune responses
    • C. Thery, M. Ostrowski, and E. Segura, "Membrane vesicles as conveyors of immune responses, " Nature Reviews Immunology, vol. 9, no. 8, pp. 581-593, 2009.
    • (2009) Nature Reviews Immunology , vol.9 , Issue.8 , pp. 581-593
    • Thery, C.1    Ostrowski, M.2    Segura, E.3
  • 25
    • 0023645106 scopus 로고
    • Vesicle formation during reticulocyte maturation. Association of plasma membrane activities with released vesicles (exosomes)
    • R. M. Johnstone, M. Adam, J. R. Hammond, L. Orr, and C. Turbide, "Vesicle formation during reticulocyte maturation. Association of plasma membrane activities with released vesicles (exosomes), " The Journal of Biological Chemistry, vol. 262, no. 19, pp. 9412-9420, 1987.
    • (1987) The Journal of Biological Chemistry , vol.262 , Issue.19 , pp. 9412-9420
    • Johnstone, R.M.1    Adam, M.2    Hammond, J.R.3    Orr, L.4    Turbide, C.5
  • 26
    • 0035877018 scopus 로고    scopus 로고
    • Proteomic analysis of dendritic cell-derived exosomes: A secreted subcellular compartment distinct from apoptotic vesicles
    • C. Thery, M. Boussac, P. Véron et al., "Proteomic analysis of dendritic cell-derived exosomes: a secreted subcellular compartment distinct from apoptotic vesicles, " Journal of Immunology, vol. 166, no. 12, pp. 7309-7318, 2001.
    • (2001) Journal of Immunology , vol.166 , Issue.12 , pp. 7309-7318
    • Thery, C.1    Boussac, M.2    Véron, P.3
  • 27
    • 0040089526 scopus 로고    scopus 로고
    • Molecular characterization of dendritic cell-derived exosomes. Selective accumulation of the heat shock protein hsc73
    • C. Thery, A. Regnault, J. Garin et al., "Molecular characterization of dendritic cell-derived exosomes. Selective accumulation of the heat shock protein hsc73, " The Journal of Cell Biology, vol. 147, no. 3, pp. 599-610, 1999.
    • (1999) The Journal of Cell Biology , vol.147 , Issue.3 , pp. 599-610
    • Thery, C.1    Regnault, A.2    Garin, J.3
  • 28
    • 70350449455 scopus 로고    scopus 로고
    • ExoCarta: A compendium of exosomal proteins and RNA
    • S. Mathivanan and R. J. Simpson, "ExoCarta: a compendium of exosomal proteins and RNA, " Proteomics, vol. 9, no. 21, pp. 4997-5000, 2009.
    • (2009) Proteomics , vol.9 , Issue.21 , pp. 4997-5000
    • Mathivanan, S.1    Simpson, R.J.2
  • 29
    • 79551542416 scopus 로고    scopus 로고
    • Selective transfer of exosomes from oligodendrocytes to microglia by macropinocytosis
    • D. Fitzner, M. Schnaars, D. van Rossum et al., "Selective transfer of exosomes from oligodendrocytes to microglia by macropinocytosis, " Journal of Cell Science, vol. 124, Part 3, pp. 447-458, 2011.
    • (2011) Journal of Cell Science , vol.124 , pp. 447-458
    • Fitzner, D.1    Schnaars, M.2    Van Rossum, D.3
  • 30
    • 84905851427 scopus 로고    scopus 로고
    • Exosome uptake through clathrin-mediated endocytosis and macropinocytosis and mediating miR-21 delivery
    • article 24951588
    • T. Tian, Y. L. Zhu, Y. Y. Zhou et al., "Exosome uptake through clathrin-mediated endocytosis and macropinocytosis and mediating miR-21 delivery, " The Journal of Biological Chemistry, vol. 289, no. 32, article 24951588, pp. 22258-22267, 2014.
    • (2014) The Journal of Biological Chemistry , vol.289 , Issue.32 , pp. 22258-22267
    • Tian, T.1    Zhu, Y.L.2    Zhou, Y.Y.3
  • 31
    • 84879046970 scopus 로고    scopus 로고
    • Exosome uptake depends on ERK1/2-heat shock protein 27 signaling and lipid raft-mediated endocytosis negatively regulated by caveolin-1
    • K. J. Svensson, H. C. Christianson, A. Wittrup et al., "Exosome uptake depends on ERK1/2-heat shock protein 27 signaling and lipid raft-mediated endocytosis negatively regulated by caveolin-1, " The Journal of Biological Chemistry, vol. 288, no. 24, pp. 17713-17724, 2013.
    • (2013) The Journal of Biological Chemistry , vol.288 , Issue.24 , pp. 17713-17724
    • Svensson, K.J.1    Christianson, H.C.2    Wittrup, A.3
  • 32
    • 84939865125 scopus 로고    scopus 로고
    • Gap junctional protein Cx43 is involved in the communication between extracellular vesicles and mammalian cells
    • article 13243
    • A. R. Soares, T. Martins-Marques, T. Ribeiro-Rodrigues et al., "Gap junctional protein Cx43 is involved in the communication between extracellular vesicles and mammalian cells, " Scientific Reports, vol. 5, article 13243, 2015
    • (2015) Scientific Reports , vol.5
    • Soares, A.R.1    Martins-Marques, T.2    Ribeiro-Rodrigues, T.3
  • 33
    • 67949097489 scopus 로고    scopus 로고
    • Exosomes-vesicular carriers for intercellular communication
    • M. Simons and G. Raposo, "Exosomes-vesicular carriers for intercellular communication, " Current Opinion in Cell Biology, vol. 21, no. 4, pp. 575-581, 2009.
    • (2009) Current Opinion in Cell Biology , vol.21 , Issue.4 , pp. 575-581
    • Simons, M.1    Raposo, G.2
  • 34
    • 79955070767 scopus 로고    scopus 로고
    • Unidirectional transfer of microRNA-loaded exosomes from T cells to antigen-presenting cells
    • M. Mittelbrunn, C. Gutiérrez-Vázquez, C. Villarroya-Beltri et al., "Unidirectional transfer of microRNA-loaded exosomes from T cells to antigen-presenting cells, " Nature Communications, vol. 2, p. 282, 2011.
    • (2011) Nature Communications , vol.2 , pp. 282
    • Mittelbrunn, M.1    Gutiérrez-Vázquez, C.2    Villarroya-Beltri, C.3
  • 35
    • 77954724494 scopus 로고    scopus 로고
    • Cardiomyocyte progenitor cell-derived exosomes stimulate migration of endothelial cells
    • K. R. Vrijsen, J. P. Sluijter, M. W. Schuchardt et al., "Cardiomyocyte progenitor cell-derived exosomes stimulate migration of endothelial cells, " Journal of Cellular and Molecular Medicine, vol. 14, no. 5, pp. 1064-1070, 2010.
    • (2010) Journal of Cellular and Molecular Medicine , vol.14 , Issue.5 , pp. 1064-1070
    • Vrijsen, K.R.1    Sluijter, J.P.2    Schuchardt, M.W.3
  • 36
    • 84908110212 scopus 로고    scopus 로고
    • Cross talk of combined gene and cell therapy in ischemic heart disease: Role of exosomal microRNA transfer
    • S. G. Ong, W. H. Lee, M. Huang et al., "Cross talk of combined gene and cell therapy in ischemic heart disease: role of exosomal microRNA transfer, " Circulation, vol. 130, no. 11, Supplement 1, pp. S60-S69, 2014.
    • (2014) Circulation , vol.130 , Issue.11 , pp. S60-S69
    • Ong, S.G.1    Lee, W.H.2    Huang, M.3
  • 37
    • 84947201437 scopus 로고    scopus 로고
    • Exosomes secreted from GATA-4 overexpressing mesenchymal stem cells serve as a reservoir of anti-apoptotic microRNAs for cardioprotection
    • B. Yu, H. W. Kim, M. Gong et al., "Exosomes secreted from GATA-4 overexpressing mesenchymal stem cells serve as a reservoir of anti-apoptotic microRNAs for cardioprotection, " International Journal of Cardiology, vol. 182, pp. 349-360, 2015.
    • (2015) International Journal of Cardiology , vol.182 , pp. 349-360
    • Yu, B.1    Kim, H.W.2    Gong, M.3
  • 38
    • 84938578435 scopus 로고    scopus 로고
    • Embryonic stem cell-derived exosomes promote endogenous repair mechanisms and enhance cardiac function following myocardial infarction
    • M. Khan, E. Nickoloff, T. Abramova et al., "Embryonic stem cell-derived exosomes promote endogenous repair mechanisms and enhance cardiac function following myocardial infarction, " Circulation Research, vol. 117, no. 1, pp. 52-64, 2015.
    • (2015) Circulation Research , vol.117 , Issue.1 , pp. 52-64
    • Khan, M.1    Nickoloff, E.2    Abramova, T.3
  • 39
    • 84857708170 scopus 로고    scopus 로고
    • Atheroprotective communication between endothelial cells and smooth muscle cells through miRNAs
    • E. Hergenreider, S. Heydt, K. Tréguer et al., "Atheroprotective communication between endothelial cells and smooth muscle cells through miRNAs, " Nature Cell Biology, vol. 14, no. 3, pp. 249-256, 2012.
    • (2012) Nature Cell Biology , vol.14 , Issue.3 , pp. 249-256
    • Hergenreider, E.1    Heydt, S.2    Tréguer, K.3
  • 40
    • 84895444013 scopus 로고    scopus 로고
    • Exosomes and cardiac repair after myocardial infarction
    • S. Sahoo and D. W. Losordo, "Exosomes and cardiac repair after myocardial infarction, " Circulation Research, vol. 114, no. 2, pp. 333-344, 2014.
    • (2014) Circulation Research , vol.114 , Issue.2 , pp. 333-344
    • Sahoo, S.1    Losordo, D.W.2
  • 41
    • 84871382105 scopus 로고    scopus 로고
    • Ultrastructural evidence of exosome secretion by progenitor cells in adult mouse myocardium and adult human cardiospheres
    • Article ID 354605
    • L. Barile, M. Gherghiceanu, L. M. Popescu, T. Moccetti, and G. Vassalli, "Ultrastructural evidence of exosome secretion by progenitor cells in adult mouse myocardium and adult human cardiospheres, " Journal of Biomedicine & Biotechnology, vol. 2012, Article ID 354605, 2012.
    • (2012) Journal of Biomedicine & Biotechnology , vol.2012
    • Barile, L.1    Gherghiceanu, M.2    Popescu, L.M.3    Moccetti, T.4    Vassalli, G.5
  • 43
    • 84994547477 scopus 로고    scopus 로고
    • Cardiac progenitor cell-derived exosomes prevent cardiomyocytes apoptosis through exosomal miR-21 by targeting PDCD4
    • article e2277
    • J. Xiao, Y. Pan, X. H. Li et al., "Cardiac progenitor cell-derived exosomes prevent cardiomyocytes apoptosis through exosomal miR-21 by targeting PDCD4, " Cell Death & Disease, vol. 7, no. 6, article e2277, 2016.
    • (2016) Cell Death & Disease , vol.7 , Issue.6
    • Xiao, J.1    Pan, Y.2    Li, X.H.3
  • 44
    • 84864284695 scopus 로고    scopus 로고
    • Sonic hedgehogmodified human CD34+ cells preserve cardiac function after acute myocardial infarction
    • A. R. Mackie, E. Klyachko, T. Thorne et al., "Sonic hedgehogmodified human CD34+ cells preserve cardiac function after acute myocardial infarction, " Circulation Research, vol. 111, no. 3, pp. 312-321, 2012.
    • (2012) Circulation Research , vol.111 , Issue.3 , pp. 312-321
    • Mackie, A.R.1    Klyachko, E.2    Thorne, T.3
  • 45
    • 80052969709 scopus 로고    scopus 로고
    • Exosomes from human CD34(+) stem cells mediate their proangiogenic paracrine activity
    • S. Sahoo, E. Klychko, T. Thorne et al., "Exosomes from human CD34(+) stem cells mediate their proangiogenic paracrine activity, " Circulation Research, vol. 109, no. 7, pp. 724-728, 2011.
    • (2011) Circulation Research , vol.109 , Issue.7 , pp. 724-728
    • Sahoo, S.1    Klychko, E.2    Thorne, T.3
  • 46
    • 84870239895 scopus 로고    scopus 로고
    • Exosomes mediate the cytoprotective action of mesenchymal stromal cells on hypoxia-induced pulmonary hypertension
    • C. Lee, S. A. Mitsialis, M. Aslam et al., "Exosomes mediate the cytoprotective action of mesenchymal stromal cells on hypoxia-induced pulmonary hypertension, " Circulation, vol. 126, no. 22, pp. 2601-2611, 2012.
    • (2012) Circulation , vol.126 , Issue.22 , pp. 2601-2611
    • Lee, C.1    Mitsialis, S.A.2    Aslam, M.3
  • 47
    • 84873919177 scopus 로고    scopus 로고
    • Mesenchymal stem cell-derived exosomes increase ATP levels, decrease oxidative stress and activate PI3K/Akt pathway to enhance myocardial viability and prevent adverse remodeling after myocardial ischemia/reperfusion injury
    • F. Arslan, R. C. Lai, M. B. Smeets et al., "Mesenchymal stem cell-derived exosomes increase ATP levels, decrease oxidative stress and activate PI3K/Akt pathway to enhance myocardial viability and prevent adverse remodeling after myocardial ischemia/reperfusion injury, " Stem Cell Research, vol. 10, no. 3, pp. 301-312, 2013.
    • (2013) Stem Cell Research , vol.10 , Issue.3 , pp. 301-312
    • Arslan, F.1    Lai, R.C.2    Smeets, M.B.3
  • 48
    • 77952293014 scopus 로고    scopus 로고
    • Exosome secreted by MSC reduces myocardial ischemia/reperfusion injury
    • R. C. Lai, F. Arslan, M. M. Lee et al., "Exosome secreted by MSC reduces myocardial ischemia/reperfusion injury, " Stem Cell Research, vol. 4, no. 3, pp. 214-222, 2010.
    • (2010) Stem Cell Research , vol.4 , Issue.3 , pp. 214-222
    • Lai, R.C.1    Arslan, F.2    Lee, M.M.3
  • 49
    • 84898461927 scopus 로고    scopus 로고
    • Extracellular vesicles derived from human bone marrow mesenchymal stem cells promote angiogenesis in a rat myocardial infarction model
    • S. Bian, L. Zhang, L. Duan, X. Wang, Y. Min, and H. Yu, "Extracellular vesicles derived from human bone marrow mesenchymal stem cells promote angiogenesis in a rat myocardial infarction model, " Journal of molecular medicine, vol. 92, no. 4, pp. 387-397, 2014.
    • (2014) Journal of Molecular Medicine , vol.92 , Issue.4 , pp. 387-397
    • Bian, S.1    Zhang, L.2    Duan, L.3    Wang, X.4    Min, Y.5    Yu, H.6
  • 50
    • 85012215389 scopus 로고    scopus 로고
    • MiRNA-sequence indicates that mesenchymal stem cells and exosomes have similar mechanism to enhance cardiac repair
    • Article ID 4150705
    • L. Shao, Y. Zhang, B. Lan et al., "MiRNA-sequence indicates that mesenchymal stem cells and exosomes have similar mechanism to enhance cardiac repair, " BioMed Research International, vol. 2017, Article ID 4150705, 2017.
    • (2017) BioMed Research International , vol.2017
    • Shao, L.1    Zhang, Y.2    Lan, B.3
  • 51
    • 84897808834 scopus 로고    scopus 로고
    • Ischemic preconditioning potentiates the protective effect of stem cells through secretion of exosomes by targeting Mecp2 via miR-22
    • article e88685
    • Y. Feng, W. Huang, M. Wani, X. Yu, and M. Ashraf, "Ischemic preconditioning potentiates the protective effect of stem cells through secretion of exosomes by targeting Mecp2 via miR-22, " PLoS One, vol. 9, no. 2, article e88685, 2014.
    • (2014) PLoS One , vol.9 , Issue.2
    • Feng, Y.1    Huang, W.2    Wani, M.3    Yu, X.4    Ashraf, M.5
  • 52
    • 84894239930 scopus 로고    scopus 로고
    • Cardioprotection by remote ischemic preconditioning of the rat heart is mediated by extracellular vesicles
    • Z. Giricz, Z. V. Varga, T. Baranyai et al., "Cardioprotection by remote ischemic preconditioning of the rat heart is mediated by extracellular vesicles, " Journal of Molecular and Cellular Cardiology, vol. 68, pp. 75-78, 2014.
    • (2014) Journal of Molecular and Cellular Cardiology , vol.68 , pp. 75-78
    • Giricz, Z.1    Varga, Z.V.2    Baranyai, T.3
  • 53
    • 48249084525 scopus 로고    scopus 로고
    • Progenitor cells isolated from the human heart: A potential cell source for regenerative therapy
    • P. van Vliet, M. Roccio, A. M. Smits et al., "Progenitor cells isolated from the human heart: a potential cell source for regenerative therapy, " Netherlands Heart Journal, vol. 16, no. 5, pp. 163-169, 2008.
    • (2008) Netherlands Heart Journal , vol.16 , Issue.5 , pp. 163-169
    • Van Vliet, P.1    Roccio, M.2    Smits, A.M.3
  • 54
    • 67651095942 scopus 로고    scopus 로고
    • Human cardiomyocyte progenitor cell transplantation preserves long-term function of the infarcted mouse myocardium
    • A. M. Smits, L. W. van Laake, K. den Ouden et al., "Human cardiomyocyte progenitor cell transplantation preserves long-term function of the infarcted mouse myocardium, " Cardiovascular Research, vol. 83, no. 3, pp. 527-535, 2009.
    • (2009) Cardiovascular Research , vol.83 , Issue.3 , pp. 527-535
    • Smits, A.M.1    Van Laake, L.W.2    Den Ouden, K.3
  • 55
    • 84907337461 scopus 로고    scopus 로고
    • Extracellular vesicles from human cardiac progenitor cells inhibit cardiomyocyte apoptosis and improve cardiac function after myocardial infarction
    • L. Barile, V. Lionetti, E. Cervio et al., "Extracellular vesicles from human cardiac progenitor cells inhibit cardiomyocyte apoptosis and improve cardiac function after myocardial infarction, " Cardiovascular Research, vol. 103, no. 4, pp. 530-541, 2014.
    • (2014) Cardiovascular Research , vol.103 , Issue.4 , pp. 530-541
    • Barile, L.1    Lionetti, V.2    Cervio, E.3
  • 56
    • 85012302304 scopus 로고    scopus 로고
    • Y RNA fragment in extracellular vesicles confers cardioprotection via modulation of IL-10 expression and secretion
    • L. Cambier, G. de Couto, A. Ibrahim et al., "Y RNA fragment in extracellular vesicles confers cardioprotection via modulation of IL-10 expression and secretion, " EMBO Molecular Medicine, vol. 9, no. 3, pp. 337-352, 2017.
    • (2017) EMBO Molecular Medicine , vol.9 , Issue.3 , pp. 337-352
    • Cambier, L.1    De Couto, G.2    Ibrahim, A.3
  • 58
    • 84975745595 scopus 로고    scopus 로고
    • Comprehensive proteomic analysis of mesenchymal stem cell exosomes reveals modulation of angiogenesis via nuclear factor-KappaB signaling
    • J. D. Anderson, H. J. Johansson, C. S. Graham et al., "Comprehensive proteomic analysis of mesenchymal stem cell exosomes reveals modulation of angiogenesis via nuclear factor-KappaB signaling, " Stem Cells, vol. 34, no. 3, pp. 601-613, 2016.
    • (2016) Stem Cells , vol.34 , Issue.3 , pp. 601-613
    • Anderson, J.D.1    Johansson, H.J.2    Graham, C.S.3
  • 59
    • 85016255446 scopus 로고    scopus 로고
    • Human pericardial fluid contains exosomes enriched with cardiovascular-expressed microRNAs and promotes therapeutic angiogenesis
    • C. Beltrami, M. Besnier, S. Shantikumar et al., "Human pericardial fluid contains exosomes enriched with cardiovascular-expressed microRNAs and promotes therapeutic angiogenesis, " Molecular Therapy, vol. 25, no. 3, pp. 679-693, 2017.
    • (2017) Molecular Therapy , vol.25 , Issue.3 , pp. 679-693
    • Beltrami, C.1    Besnier, M.2    Shantikumar, S.3
  • 60
    • 85018523241 scopus 로고    scopus 로고
    • Enhanced proangiogenic potential of mesenchymal stem cell-derived exosomes stimulated by a nitric oxide releasing polymer
    • W. Du, K. Zhang, S. Zhang et al., "Enhanced proangiogenic potential of mesenchymal stem cell-derived exosomes stimulated by a nitric oxide releasing polymer, " Biomaterials, vol. 133, pp. 70-81, 2017.
    • (2017) Biomaterials , vol.133 , pp. 70-81
    • Du, W.1    Zhang, K.2    Zhang, S.3
  • 61
    • 85022226203 scopus 로고    scopus 로고
    • Mesenchymal stem cells release exosomes that transfer miRNAs to endothelial cells and promote angiogenesis
    • M. Gong, B. Yu, J. Wang et al., "Mesenchymal stem cells release exosomes that transfer miRNAs to endothelial cells and promote angiogenesis, " Oncotarget, vol. 8, no. 28, pp. 45200-45212, 2017.
    • (2017) Oncotarget , vol.8 , Issue.28 , pp. 45200-45212
    • Gong, M.1    Yu, B.2    Wang, J.3
  • 62
    • 85018933821 scopus 로고    scopus 로고
    • Hypoxia inducible factor-1alpha potentiates jagged 1-mediated angiogenesis by mesenchymal stem cell-derived exosomes
    • H. Gonzalez-King, N. A. García, I. Ontoria-Oviedo, M. Ciria, J. A. Montero, and P. Sepúlveda, "Hypoxia inducible factor-1alpha potentiates jagged 1-mediated angiogenesis by mesenchymal stem cell-derived exosomes, " Stem Cells, vol. 35, no. 7, pp. 1747-1759, 2017.
    • (2017) Stem Cells , vol.35 , Issue.7 , pp. 1747-1759
    • Gonzalez-King, H.1    García, N.A.2    Ontoria-Oviedo, I.3    Ciria, M.4    Montero, J.A.5    Sepúlveda, P.6
  • 63
    • 84929649938 scopus 로고    scopus 로고
    • Exosomes secreted from CXCR4 overexpressing mesenchymal stem cells promote cardioprotection via Akt signaling pathway following myocardial infarction
    • Article ID 659890
    • K. Kang, R. Ma, W. Cai et al., "Exosomes secreted from CXCR4 overexpressing mesenchymal stem cells promote cardioprotection via Akt signaling pathway following myocardial infarction, " Stem Cells International, vol. 2015, Article ID 659890, 2015.
    • (2015) Stem Cells International , vol.2015
    • Kang, K.1    Ma, R.2    Cai, W.3
  • 64
    • 85017344289 scopus 로고    scopus 로고
    • Exosomes derived from Aktmodified human umbilical cord mesenchymal stem cells improve cardiac regeneration and promote angiogenesis via activating platelet-derived growth factor D
    • J. Ma, Y. Zhao, L. Sun et al., "Exosomes derived from Aktmodified human umbilical cord mesenchymal stem cells improve cardiac regeneration and promote angiogenesis via activating platelet-derived growth factor D, " Stem Cells Translational Medicine, vol. 6, no. 1, pp. 51-59, 2017.
    • (2017) Stem Cells Translational Medicine , vol.6 , Issue.1 , pp. 51-59
    • Ma, J.1    Zhao, Y.2    Sun, L.3
  • 65
    • 85015663550 scopus 로고    scopus 로고
    • Angiogenic mechanisms of human CD34+ stem cell exosomes in the repair of ischemic hindlimb
    • P. Mathiyalagan, Y. Liang, D. Kim et al., "Angiogenic mechanisms of human CD34+ stem cell exosomes in the repair of ischemic hindlimb, " Circulation Research, 2017.
    • (2017) Circulation Research
    • Mathiyalagan, P.1    Liang, Y.2    Kim, D.3
  • 66
    • 84949591265 scopus 로고    scopus 로고
    • Mesenchymal stem cell-derived exosomes improve the microenvironment of infarcted myocardium contributing to angiogenesis and anti-inflammation
    • X. Teng, L. Chen, W. Chen, J. Yang, Z. Yang, and Z. Shen, "Mesenchymal stem cell-derived exosomes improve the microenvironment of infarcted myocardium contributing to angiogenesis and anti-inflammation, " Cellular Physiology and Biochemistry, vol. 37, no. 6, pp. 2415-2424, 2015.
    • (2015) Cellular Physiology and Biochemistry , vol.37 , Issue.6 , pp. 2415-2424
    • Teng, X.1    Chen, L.2    Chen, W.3    Yang, J.4    Yang, Z.5    Shen, Z.6
  • 67
    • 84997815986 scopus 로고    scopus 로고
    • Pretreatment of cardiac stem cells with exosomes derived from mesenchymal stem cells enhances myocardial repair
    • Z. Zhang, J. Yang, W. Yan, Y. Li, Z. Shen, and T. Asahara, "Pretreatment of cardiac stem cells with exosomes derived from mesenchymal stem cells enhances myocardial repair, " Journal of the American Heart Association, vol. 5, no. 1, 2016.
    • (2016) Journal of the American Heart Association , vol.5 , Issue.1
    • Zhang, Z.1    Yang, J.2    Yan, W.3    Li, Y.4    Shen, Z.5    Asahara, T.6
  • 68
    • 84935874875 scopus 로고    scopus 로고
    • Exosomes derived from human umbilical cord mesenchymal stem cells relieve acute myocardial ischemic injury
    • Article ID 761643
    • Y. Zhao, X. Sun, W. Cao et al., "Exosomes derived from human umbilical cord mesenchymal stem cells relieve acute myocardial ischemic injury, " Stem Cells International, vol. 2015, Article ID 761643, 2015.
    • (2015) Stem Cells International , vol.2015
    • Zhao, Y.1    Sun, X.2    Cao, W.3
  • 69
    • 84942415059 scopus 로고    scopus 로고
    • Modulation of p38 kinase by DUSP4 is important in regulating cardiovascular function under oxidative stress
    • A. Barajas-Espinosa, A. Basye, M. G. Angelos, and C. A. Chen, "Modulation of p38 kinase by DUSP4 is important in regulating cardiovascular function under oxidative stress, " Free Radical Biology & Medicine, vol. 89, pp. 170-181, 2015.
    • (2015) Free Radical Biology & Medicine , vol.89 , pp. 170-181
    • Barajas-Espinosa, A.1    Basye, A.2    Angelos, M.G.3    Chen, C.A.4
  • 70
    • 84904959087 scopus 로고    scopus 로고
    • Redox activation of DUSP4 by N-acetylcysteine protects endothelial cells from Cd(2)(+)-induced apoptosis
    • A. Barajas-Espinosa, A. Basye, E. Jesse, H. Yan, D. Quan, and C. A. Chen, "Redox activation of DUSP4 by N-acetylcysteine protects endothelial cells from Cd(2)(+)-induced apoptosis, " Free Radical Biology & Medicine, vol. 74, pp. 188-199, 2014.
    • (2014) Free Radical Biology & Medicine , vol.74 , pp. 188-199
    • Barajas-Espinosa, A.1    Basye, A.2    Jesse, E.3    Yan, H.4    Quan, D.5    Chen, C.A.6
  • 71
    • 85042592062 scopus 로고    scopus 로고
    • Dual-specificity phosphatase 4 overexpression in cells prevents hypoxia/reoxygenation-induced apoptosis via the upregulation of eNOS
    • J. A. Dougherty, J. Kilbane Myers, M. Khan, M. G. Angelos, and C. A. Chen, "Dual-specificity phosphatase 4 overexpression in cells prevents hypoxia/reoxygenation-induced apoptosis via the upregulation of eNOS, " Frontiers in Cardiovascular Medicine, vol. 4, p. 22, 2017.
    • (2017) Frontiers in Cardiovascular Medicine , vol.4 , pp. 22
    • Dougherty, J.A.1    Kilbane Myers, J.2    Khan, M.3    Angelos, M.G.4    Chen, C.A.5
  • 72
    • 0347444723 scopus 로고    scopus 로고
    • MicroRNAs: Genomics, biogenesis, mechanism, and function
    • D. P. Bartel, "MicroRNAs: genomics, biogenesis, mechanism, and function, " Cell, vol. 116, no. 2, pp. 281-297, 2004.
    • (2004) Cell , vol.116 , Issue.2 , pp. 281-297
    • Bartel, D.P.1
  • 73
    • 4644309196 scopus 로고    scopus 로고
    • The functions of animal microRNAs
    • V. Ambros, "The functions of animal microRNAs, " Nature, vol. 431, no. 7006, pp. 350-355, 2004.
    • (2004) Nature , vol.431 , Issue.7006 , pp. 350-355
    • Ambros, V.1
  • 74
    • 34249302620 scopus 로고    scopus 로고
    • Exosome-mediated transfer of mRNAs and microRNAs is a novel mechanism of genetic exchange between cells
    • H. Valadi, K. Ekström, A. Bossios, M. Sjöstrand, J. J. Lee, and J. O. Lötvall, "Exosome-mediated transfer of mRNAs and microRNAs is a novel mechanism of genetic exchange between cells, " Nature Cell Biology, vol. 9, no. 6, pp. 654-659, 2007.
    • (2007) Nature Cell Biology , vol.9 , Issue.6 , pp. 654-659
    • Valadi, H.1    Ekström, K.2    Bossios, A.3    Sjöstrand, M.4    Lee, J.J.5    Lötvall, J.O.6
  • 75
    • 57049103401 scopus 로고    scopus 로고
    • Glioblastoma microvesicles transport RNA and proteins that promote tumour growth and provide diagnostic biomarkers
    • J. Skog, T. Würdinger, S. van Rijn et al., "Glioblastoma microvesicles transport RNA and proteins that promote tumour growth and provide diagnostic biomarkers, " Nature Cell Biology, vol. 10, no. 12, pp. 1470-1476, 2008.
    • (2008) Nature Cell Biology , vol.10 , Issue.12 , pp. 1470-1476
    • Skog, J.1    Würdinger, T.2    Van Rijn, S.3
  • 76
    • 84864411871 scopus 로고    scopus 로고
    • Selective extracellular vesiclemediated export of an overlapping set of microRNAs from multiple cell types
    • J. Guduric-Fuchs, A. O'Connor, B. Camp, C. L. O'Neill, R. J. Medina, and D. A. Simpson, "Selective extracellular vesiclemediated export of an overlapping set of microRNAs from multiple cell types, " BMC Genomics, vol. 13, p. 357, 2012.
    • (2012) BMC Genomics , vol.13 , pp. 357
    • Guduric-Fuchs, J.1    O'Connor, A.2    Camp, B.3    O'Neill, C.L.4    Medina, R.J.5    Simpson, D.A.6
  • 77
    • 84922527336 scopus 로고    scopus 로고
    • Endogenous RNAs modulate microRNA sorting to exosomes and transfer to acceptor cells
    • M. L. Squadrito, C. Baer, F. Burdet et al., "Endogenous RNAs modulate microRNA sorting to exosomes and transfer to acceptor cells, " Cell Reports, vol. 8, no. 5, pp. 1432-1446, 2014.
    • (2014) Cell Reports , vol.8 , Issue.5 , pp. 1432-1446
    • Squadrito, M.L.1    Baer, C.2    Burdet, F.3
  • 78
    • 48049086320 scopus 로고    scopus 로고
    • Myocardial induction of nucleostemin in response to postnatal growth and pathological challenge
    • S. Siddiqi, N. Gude, T. Hosoda et al., "Myocardial induction of nucleostemin in response to postnatal growth and pathological challenge, " Circulation Research, vol. 103, no. 1, pp. 89-97, 2008.
    • (2008) Circulation Research , vol.103 , Issue.1 , pp. 89-97
    • Siddiqi, S.1    Gude, N.2    Hosoda, T.3
  • 79
    • 78449254310 scopus 로고    scopus 로고
    • Genome-wide identification of targets and function of individual Micro-RNAs in mouse embryonic stem cells
    • article e1001163
    • S. A. Hanina, W. Mifsud, T. A. Down et al., "Genome-wide identification of targets and function of individual Micro-RNAs in mouse embryonic stem cells, " PLoS Genetics, vol. 6, no. 10, article e1001163, 2010.
    • (2010) PLoS Genetics , vol.6 , Issue.10
    • Hanina, S.A.1    Mifsud, W.2    Down, T.A.3
  • 80
    • 65249115670 scopus 로고    scopus 로고
    • Involvement of microRNAs in hydrogen peroxidemediated gene regulation and cellular injury response in vascular smooth muscle cells
    • Y. Lin, X. Liu, Y. Cheng, J. Yang, Y. Huo, and C. Zhang, "Involvement of microRNAs in hydrogen peroxidemediated gene regulation and cellular injury response in vascular smooth muscle cells, " The Journal of Biological Chemistry, vol. 284, no. 12, pp. 7903-7913, 2009.
    • (2009) The Journal of Biological Chemistry , vol.284 , Issue.12 , pp. 7903-7913
    • Lin, Y.1    Liu, X.2    Cheng, Y.3    Yang, J.4    Huo, Y.5    Zhang, C.6
  • 81
    • 84957631447 scopus 로고    scopus 로고
    • ERK8 is a novel HuR kinase that regulates tumour suppressor PDCD4 through a miR-21 dependent mechanism
    • U. Liwak-Muir, C. C. Dobson, T. Naing et al., "ERK8 is a novel HuR kinase that regulates tumour suppressor PDCD4 through a miR-21 dependent mechanism, " Oncotarget, vol. 7, no. 2, pp. 1439-1450, 2016.
    • (2016) Oncotarget , vol.7 , Issue.2 , pp. 1439-1450
    • Liwak-Muir, U.1    Dobson, C.C.2    Naing, T.3
  • 82
    • 84873713781 scopus 로고    scopus 로고
    • Cardiac progenitor-derived exosomes protect ischemic myocardium from acute ischemia/ reperfusion injury
    • L. Chen, Y. Wang, Y. Pan et al., "Cardiac progenitor-derived exosomes protect ischemic myocardium from acute ischemia/ reperfusion injury, " Biochemical and Biophysical Research Communications, vol. 431, no. 3, pp. 566-571, 2013.
    • (2013) Biochemical and Biophysical Research Communications , vol.431 , Issue.3 , pp. 566-571
    • Chen, L.1    Wang, Y.2    Pan, Y.3
  • 83
    • 77957225240 scopus 로고    scopus 로고
    • Synergistic effects of the GATA-4-mediated miR-144/451 cluster in protection against simulated ischemia/reperfusion-induced cardiomyocyte death
    • X. Zhang, X. Wang, H. Zhu et al., "Synergistic effects of the GATA-4-mediated miR-144/451 cluster in protection against simulated ischemia/reperfusion-induced cardiomyocyte death, " Journal of Molecular and Cellular Cardiology, vol. 49, no. 5, pp. 841-850, 2010.
    • (2010) Journal of Molecular and Cellular Cardiology , vol.49 , Issue.5 , pp. 841-850
    • Zhang, X.1    Wang, X.2    Zhu, H.3
  • 84
    • 84887617444 scopus 로고    scopus 로고
    • GATA4 loss-offunction mutations underlie familial tetralogy of fallot
    • Y. Q. Yang, L. Gharibeh, R. G. Li et al., "GATA4 loss-offunction mutations underlie familial tetralogy of fallot, " Human Mutation, vol. 34, no. 12, pp. 1662-1671, 2013.
    • (2013) Human Mutation , vol.34 , Issue.12 , pp. 1662-1671
    • Yang, Y.Q.1    Gharibeh, L.2    Li, R.G.3
  • 85
    • 85006302151 scopus 로고    scopus 로고
    • Disease model of GATA4 mutation reveals transcription factor cooperativity in human cardiogenesis
    • Y. S. Ang, R. N. Rivas, A. J. Ribeiro et al., "Disease model of GATA4 mutation reveals transcription factor cooperativity in human cardiogenesis, " Cell, vol. 167, no. 7, pp. 1734-1749 e22, 2016.
    • (2016) Cell , vol.167 , Issue.7 , pp. 1734-1749e22
    • Ang, Y.S.1    Rivas, R.N.2    Ribeiro, A.J.3
  • 86
    • 34347376692 scopus 로고    scopus 로고
    • Characterization of microRNA expression profiles in normal human tissues
    • Y. Liang, D. Ridzon, L. Wong, and C. Chen, "Characterization of microRNA expression profiles in normal human tissues, " BMC Genomics, vol. 8, p. 166, 2007.
    • (2007) BMC Genomics , vol.8 , pp. 166
    • Liang, Y.1    Ridzon, D.2    Wong, L.3    Chen, C.4
  • 87
    • 84923791608 scopus 로고    scopus 로고
    • MiR-133a enhances the protective capacity of cardiac progenitors cells after myocardial infarction
    • A. Izarra, I. Moscoso, E. Levent et al., "miR-133a enhances the protective capacity of cardiac progenitors cells after myocardial infarction, " Stem Cell Reports, vol. 3, no. 6, pp. 1029-1042, 2014.
    • (2014) Stem Cell Reports , vol.3 , Issue.6 , pp. 1029-1042
    • Izarra, A.1    Moscoso, I.2    Levent, E.3
  • 88
    • 85000631212 scopus 로고    scopus 로고
    • Experimental, systems, and computational approaches to understanding the microRNA-mediated reparative potential of cardiac progenitor cell-derived exosomes from pediatric patients
    • U. Agarwal, A. George, S. Bhutani et al., "Experimental, systems, and computational approaches to understanding the microRNA-mediated reparative potential of cardiac progenitor cell-derived exosomes from pediatric patients, " Circulation Research, vol. 120, no. 4, pp. 701-712, 2017.
    • (2017) Circulation Research , vol.120 , Issue.4 , pp. 701-712
    • Agarwal, U.1    George, A.2    Bhutani, S.3
  • 89
    • 84949058258 scopus 로고    scopus 로고
    • Correction: Evaluation of changes in morphology and function of human induced pluripotent stem cell derived cardiomyocytes (HiPSC-CMs) cultured on an aligned-nanofiber cardiac patch
    • article e0141176
    • M. Khan, Y. Xu, S. Hua et al., "Correction: evaluation of changes in morphology and function of human induced pluripotent stem cell derived cardiomyocytes (HiPSC-CMs) cultured on an aligned-nanofiber cardiac patch, " PLoS One, vol. 10, no. 10, article e0141176, 2015.
    • (2015) PLoS One , vol.10 , Issue.10
    • Khan, M.1    Xu, Y.2    Hua, S.3
  • 90
    • 85017330743 scopus 로고    scopus 로고
    • Comparison of human induced pluripotent stem-cell derived cardiomyocytes with human mesenchymal stem cells following acute myocardial infarction
    • article e116281
    • L. Citro, S. Naidu, F. Hassan et al., "Comparison of human induced pluripotent stem-cell derived cardiomyocytes with human mesenchymal stem cells following acute myocardial infarction, " PLoS One, vol. 9, no. 12, article e116281, 2014.
    • (2014) PLoS One , vol.9 , Issue.12
    • Citro, L.1    Naidu, S.2    Hassan, F.3
  • 91
    • 84929504046 scopus 로고    scopus 로고
    • MicroRNA expression in circulating microvesicles predicts cardiovascular events in patients with coronary artery disease
    • article e001249
    • F. Jansen, X. Yang, S. Proebsting et al., "MicroRNA expression in circulating microvesicles predicts cardiovascular events in patients with coronary artery disease, " Journal of the American Heart Association, vol. 3, no. 6, article e001249, 2014.
    • (2014) Journal of the American Heart Association , vol.3 , Issue.6
    • Jansen, F.1    Yang, X.2    Proebsting, S.3
  • 92
    • 84871322435 scopus 로고    scopus 로고
    • Loss of angiomiR-126 and 130a in angiogenic early outgrowth cells from patients with chronic heart failure: Role for impaired in vivo neovascularization and cardiac repair capacity
    • P. Jakob, C. Doerries, S. Briand et al., "Loss of angiomiR-126 and 130a in angiogenic early outgrowth cells from patients with chronic heart failure: role for impaired in vivo neovascularization and cardiac repair capacity, " Circulation, vol. 126, no. 25, pp. 2962-2975, 2012.
    • (2012) Circulation , vol.126 , Issue.25 , pp. 2962-2975
    • Jakob, P.1    Doerries, C.2    Bri, S.3
  • 93
    • 48749130187 scopus 로고    scopus 로고
    • MiR-126 regulates angiogenic signaling and vascular integrity
    • J. E. Fish, M. M. Santoro, S. U. Morton et al., "miR-126 regulates angiogenic signaling and vascular integrity, " Developmental Cell, vol. 15, no. 2, pp. 272-284, 2008.
    • (2008) Developmental Cell , vol.15 , Issue.2 , pp. 272-284
    • Fish, J.E.1    Santoro, M.M.2    Morton, S.U.3
  • 94
    • 65249185780 scopus 로고    scopus 로고
    • Downregulation of miR-199a derepresses hypoxia-inducible factor-1alpha and sirtuin 1 and recapitulates hypoxia preconditioning in cardiac myocytes
    • S. Rane, M. He, D. Sayed et al., "Downregulation of miR-199a derepresses hypoxia-inducible factor-1alpha and sirtuin 1 and recapitulates hypoxia preconditioning in cardiac myocytes, " Circulation Research, vol. 104, no. 7, pp. 879-886, 2009.
    • (2009) Circulation Research , vol.104 , Issue.7 , pp. 879-886
    • Rane, S.1    He, M.2    Sayed, D.3
  • 95
    • 85020193540 scopus 로고    scopus 로고
    • MiR199a-3p regulates P53 by targeting CABLES1 in mouse cardiac c-kit+ cells to promote proliferation and inhibit apoptosis through a negative feedback loop
    • J. Liu, Y. Wang, J. Cui et al., "miR199a-3p regulates P53 by targeting CABLES1 in mouse cardiac c-kit+ cells to promote proliferation and inhibit apoptosis through a negative feedback loop, " Stem Cell Research & Therapy, vol. 8, no. 1, p. 127, 2017.
    • (2017) Stem Cell Research & Therapy , vol.8 , Issue.1 , pp. 127
    • Liu, J.1    Wang, Y.2    Cui, J.3
  • 96
    • 80052760391 scopus 로고    scopus 로고
    • Increased microRNA-1 and microRNA-133a levels in serum of patients with cardiovascular disease indicate myocardial damage
    • Y. Kuwabara, K. Ono, T. Horie et al., "Increased microRNA-1 and microRNA-133a levels in serum of patients with cardiovascular disease indicate myocardial damage, " Circulation. Cardiovascular Genetics, vol. 4, no. 4, pp. 446-454, 2011.
    • (2011) Circulation. Cardiovascular Genetics , vol.4 , Issue.4 , pp. 446-454
    • Kuwabara, Y.1    Ono, K.2    Horie, T.3
  • 97
    • 84957709967 scopus 로고    scopus 로고
    • Exosomal transfer of miR-30a between cardiomyocytes regulates autophagy after hypoxia
    • Y. Yang, Y. Li, X. Chen, X. Cheng, Y. Liao, and X. Yu, "Exosomal transfer of miR-30a between cardiomyocytes regulates autophagy after hypoxia, " Journal of Molecular Medicine, vol. 94, no. 6, pp. 711-724, 2016.
    • (2016) Journal of Molecular Medicine , vol.94 , Issue.6 , pp. 711-724
    • Yang, Y.1    Li, Y.2    Chen, X.3    Cheng, X.4    Liao, Y.5    Yu, X.6
  • 98
    • 84880770209 scopus 로고    scopus 로고
    • Circulating p53-responsive microRNAs are predictive indicators of heart failure after acute myocardial infarction
    • S. Matsumoto, Y. Sakata, S. Suna et al., "Circulating p53-responsive microRNAs are predictive indicators of heart failure after acute myocardial infarction, " Circulation Research, vol. 113, no. 3, pp. 322-326, 2013.
    • (2013) Circulation Research , vol.113 , Issue.3 , pp. 322-326
    • Matsumoto, S.1    Sakata, Y.2    Suna, S.3
  • 99
    • 34249817549 scopus 로고    scopus 로고
    • Transactivation of miR-34a by p53 broadly influences gene expression and promotes apoptosis
    • T. C. Chang, E. A. Wentzel, O. A. Kent et al., "Transactivation of miR-34a by p53 broadly influences gene expression and promotes apoptosis, " Molecular Cell, vol. 26, no. 5, pp. 745-752, 2007.
    • (2007) Molecular Cell , vol.26 , Issue.5 , pp. 745-752
    • Chang, T.C.1    Wentzel, E.A.2    Kent, O.A.3
  • 100
    • 77957936826 scopus 로고    scopus 로고
    • Downregulation of p53-inducible microRNAs 192, 194, and 215 impairs the p53/MDM2 autoregulatory loop in multiple myeloma development
    • F. Pichiorri, S. S. Suh, A. Rocci et al., "Downregulation of p53-inducible microRNAs 192, 194, and 215 impairs the p53/MDM2 autoregulatory loop in multiple myeloma development, " Cancer Cell, vol. 18, no. 4, pp. 367-381, 2010.
    • (2010) Cancer Cell , vol.18 , Issue.4 , pp. 367-381
    • Pichiorri, F.1    Suh, S.S.2    Rocci, A.3
  • 101
    • 20444378130 scopus 로고    scopus 로고
    • Platelet-derived microparticles induce angiogenesis and stimulate post-ischemic revascularization
    • A. Brill, O. Dashevsky, J. Rivo, Y. Gozal, and D. Varon, "Platelet-derived microparticles induce angiogenesis and stimulate post-ischemic revascularization, " Cardiovascular Research, vol. 67, no. 1, pp. 30-38, 2005.
    • (2005) Cardiovascular Research , vol.67 , Issue.1 , pp. 30-38
    • Brill, A.1    Dashevsky, O.2    Rivo, J.3    Gozal, Y.4    Varon, D.5
  • 102
    • 84928014780 scopus 로고    scopus 로고
    • Plasma exosomes protect the myocardium from ischemiareperfusion injury
    • J. M. Vicencio, D. M. Yellon, V. Sivaraman et al., "Plasma exosomes protect the myocardium from ischemiareperfusion injury, " Journal of the American College of Cardiology, vol. 65, no. 15, pp. 1525-1536, 2015.
    • (2015) Journal of the American College of Cardiology , vol.65 , Issue.15 , pp. 1525-1536
    • Vicencio, J.M.1    Yellon, D.M.2    Sivaraman, V.3
  • 103
    • 79953858598 scopus 로고    scopus 로고
    • Delivery of siRNA to the mouse brain by systemic injection of targeted exosomes
    • L. Alvarez-Erviti, Y. Seow, H. Yin, C. Betts, S. Lakhal, and M. J. Wood, "Delivery of siRNA to the mouse brain by systemic injection of targeted exosomes, " Nature Biotechnology, vol. 29, no. 4, pp. 341-345, 2011.
    • (2011) Nature Biotechnology , vol.29 , Issue.4 , pp. 341-345
    • Alvarez-Erviti, L.1    Seow, Y.2    Yin, H.3    Betts, C.4    Lakhal, S.5    Wood, M.J.6
  • 104
    • 33646574938 scopus 로고    scopus 로고
    • Growth of teratomas derived from human pluripotent stem cells is influenced by the graft site
    • M. J. Cooke, M. Stojkovic, and S. A. Przyborski, "Growth of teratomas derived from human pluripotent stem cells is influenced by the graft site, " Stem Cells and Development, vol. 15, no. 2, pp. 254-259, 2006.
    • (2006) Stem Cells and Development , vol.15 , Issue.2 , pp. 254-259
    • Cooke, M.J.1    Stojkovic, M.2    Przyborski, S.A.3
  • 105
    • 44949187534 scopus 로고    scopus 로고
    • FDA scrutinizes human stem cell therapies
    • J. L. Fox, "FDA scrutinizes human stem cell therapies, " Nature Biotechnology, vol. 26, no. 6, pp. 598-599, 2008.
    • (2008) Nature Biotechnology , vol.26 , Issue.6 , pp. 598-599
    • Fox, J.L.1
  • 106
    • 84930477917 scopus 로고    scopus 로고
    • Concise review: Workshop review: Understanding and assessing the risks of stem cell-based therapies
    • J. A. Heslop, T. G. Hammond, I. Santeramo et al., "Concise review: workshop review: understanding and assessing the risks of stem cell-based therapies, " Stem Cells Translational Medicine, vol. 4, no. 4, pp. 389-400, 2015.
    • (2015) Stem Cells Translational Medicine , vol.4 , Issue.4 , pp. 389-400
    • Heslop, J.A.1    Hammond, T.G.2    Santeramo, I.3
  • 107
    • 84882239370 scopus 로고    scopus 로고
    • Tumorigenicity as a clinical hurdle for pluripotent stem cell therapies
    • A. S. Lee, C. Tang, M. S. Rao, I. L. Weissman, and J. C. Wu, "Tumorigenicity as a clinical hurdle for pluripotent stem cell therapies, " Nature Medicine, vol. 19, no. 8, pp. 998-1004, 2013.
    • (2013) Nature Medicine , vol.19 , Issue.8 , pp. 998-1004
    • Lee, A.S.1    Tang, C.2    Rao, M.S.3    Weissman, I.L.4    Wu, J.C.5
  • 108
    • 19544386310 scopus 로고    scopus 로고
    • Teratoma formation leads to failure of treatment for type i diabetes using embryonic stem cell-derived insulin-producing cells
    • T. Fujikawa, S. H. Oh, L. Pi, H. M. Hatch, T. Shupe, and B. E. Petersen, "Teratoma formation leads to failure of treatment for type I diabetes using embryonic stem cell-derived insulin-producing cells, " The American Journal of Pathology, vol. 166, no. 6, pp. 1781-1791, 2005.
    • (2005) The American Journal of Pathology , vol.166 , Issue.6 , pp. 1781-1791
    • Fujikawa, T.1    Oh, S.H.2    Pi, L.3    Hatch, H.M.4    Shupe, T.5    Petersen, B.E.6
  • 109
    • 61449171881 scopus 로고    scopus 로고
    • Donorderived brain tumor following neural stem cell transplantation in an ataxia telangiectasia patient
    • article e1000029
    • N. Amariglio, A. Hirshberg, B. W. Scheithauer et al., "Donorderived brain tumor following neural stem cell transplantation in an ataxia telangiectasia patient, " PLoS Medicine, vol. 6, no. 2, article e1000029, 2009.
    • (2009) PLoS Medicine , vol.6 , Issue.2
    • Amariglio, N.1    Hirshberg, A.2    Scheithauer, B.W.3
  • 110
    • 84907862127 scopus 로고    scopus 로고
    • Autograft-derived spinal cord mass following olfactory mucosal cell transplantation in a spinal cord injury patient: Case report
    • B. J. Dlouhy, O. Awe, R. C. Rao, P. A. Kirby, and P. W. Hitchon, "Autograft-derived spinal cord mass following olfactory mucosal cell transplantation in a spinal cord injury patient: case report, " Journal of Neurosurgery Spine, vol. 21, no. 4, pp. 618-622, 2014.
    • (2014) Journal of Neurosurgery Spine , vol.21 , Issue.4 , pp. 618-622
    • Dlouhy, B.J.1    Awe, O.2    Rao, R.C.3    Kirby, P.A.4    Hitchon, P.W.5
  • 111
    • 84929353279 scopus 로고    scopus 로고
    • Visualization and tracking of tumour extracellular vesicle delivery and RNA translation using multiplexed reporters
    • C. P. Lai, E. Y. Kim, C. E. Badr et al., "Visualization and tracking of tumour extracellular vesicle delivery and RNA translation using multiplexed reporters, " Nature Communications, vol. 6, p. 7029, 2015.
    • (2015) Nature Communications , vol.6 , pp. 7029
    • Lai, C.P.1    Kim, E.Y.2    Badr, C.E.3
  • 112
    • 84893437162 scopus 로고    scopus 로고
    • Dynamic biodistribution of extracellular vesicles in vivo using a multimodal imaging reporter
    • C. P. Lai, O. Mardini, M. Ericsson et al., "Dynamic biodistribution of extracellular vesicles in vivo using a multimodal imaging reporter, " ACS Nano, vol. 8, no. 1, pp. 483-494, 2014.
    • (2014) ACS Nano , vol.8 , Issue.1 , pp. 483-494
    • Lai, C.P.1    Mardini, O.2    Ericsson, M.3
  • 113
    • 0036831289 scopus 로고    scopus 로고
    • Stem cell medicine encounters the immune system
    • J. A. Bradley, E. M. Bolton, and R. A. Pedersen, "Stem cell medicine encounters the immune system, " Nature Reviews Immunology, vol. 2, no. 11, pp. 859-871, 2002.
    • (2002) Nature Reviews Immunology , vol.2 , Issue.11 , pp. 859-871
    • Bradley, J.A.1    Bolton, E.M.2    Pedersen, R.A.3
  • 114
    • 85034054886 scopus 로고    scopus 로고
    • Comprehensive toxicity and immunogenicity studies reveal minimal effects in mice following sustained dosing of extracellular vesicles derived from HEK293T cells
    • article 1324730
    • X. Zhu, M. Badawi, S. Pomeroy et al., "Comprehensive toxicity and immunogenicity studies reveal minimal effects in mice following sustained dosing of extracellular vesicles derived from HEK293T cells, " Journal of Extracellular Vesicles, vol. 6, no. 1, article 1324730, 2017.
    • (2017) Journal of Extracellular Vesicles , vol.6 , Issue.1
    • Zhu, X.1    Badawi, M.2    Pomeroy, S.3
  • 115
    • 18144372419 scopus 로고    scopus 로고
    • Vaccination of metastatic melanoma patients with autologous dendritic cell (DC) derived-exosomes: Results of the first phase i clinical trial
    • B. Escudier, T. Dorval, N. Chaput et al., "Vaccination of metastatic melanoma patients with autologous dendritic cell (DC) derived-exosomes: results of the first phase I clinical trial, " Journal of Translational Medicine, vol. 3, no. 1, p. 10, 2005.
    • (2005) Journal of Translational Medicine , vol.3 , Issue.1 , pp. 10
    • Escudier, B.1    Dorval, T.2    Chaput, N.3
  • 116
    • 18144369346 scopus 로고    scopus 로고
    • A phase i study of dexosome immunotherapy in patients with advanced nonsmall cell lung cancer
    • M. A. Morse, J. Garst, T. Osada et al., "A phase I study of dexosome immunotherapy in patients with advanced nonsmall cell lung cancer, " Journal of Translational Medicine, vol. 3, no. 1, p. 9, 2005.
    • (2005) Journal of Translational Medicine , vol.3 , Issue.1 , pp. 9
    • Morse, M.A.1    Garst, J.2    Osada, T.3
  • 117
    • 41149172340 scopus 로고    scopus 로고
    • Phase i clinical trial of autologous ascites-derived exosomes combined with GM-CSF for colorectal cancer
    • S. Dai, D. Wei, Z. Wu et al., "Phase I clinical trial of autologous ascites-derived exosomes combined with GM-CSF for colorectal cancer, " Molecular Therapy, vol. 16, no. 4, pp. 782-790, 2008.
    • (2008) Molecular Therapy , vol.16 , Issue.4 , pp. 782-790
    • Dai, S.1    Wei, D.2    Wu, Z.3
  • 118
    • 55049108092 scopus 로고    scopus 로고
    • Serial noninvasive in vivo positron emission tomographic tracking of percutaneously intramyocardially injected autologous porcine mesenchymal stem cells modified for transgene reporter gene expression
    • M. Gyongyosi, J. Blanco, T. Marian et al., "Serial noninvasive in vivo positron emission tomographic tracking of percutaneously intramyocardially injected autologous porcine mesenchymal stem cells modified for transgene reporter gene expression, " Circulation. Cardiovascular Imaging, vol. 1, no. 2, pp. 94-103, 2008.
    • (2008) Circulation. Cardiovascular Imaging , vol.1 , Issue.2 , pp. 94-103
    • Gyongyosi, M.1    Blanco, J.2    Marian, T.3
  • 119
    • 33947305414 scopus 로고    scopus 로고
    • Adult bone marrow-derived cells for cardiac repair: A systematic review and meta-analysis
    • A. Abdel-Latif, R. Bolli, I. M. Tleyjeh et al., "Adult bone marrow-derived cells for cardiac repair: a systematic review and meta-analysis, " Archives of Internal Medicine, vol. 167, no. 10, pp. 989-997, 2007.
    • (2007) Archives of Internal Medicine , vol.167 , Issue.10 , pp. 989-997
    • Abdel-Latif, A.1    Bolli, R.2    Tleyjeh, I.M.3
  • 120
    • 48749100385 scopus 로고    scopus 로고
    • Autologous bone marrow stem cells to treat acute myocardial infarction: A systematic review
    • E. Martin-Rendon, S. J. Brunskill, C. J. Hyde, S. J. Stanworth, A. Mathur, and S. M. Watt, "Autologous bone marrow stem cells to treat acute myocardial infarction: a systematic review, " European Heart Journal, vol. 29, no. 15, pp. 1807-1818, 2008.
    • (2008) European Heart Journal , vol.29 , Issue.15 , pp. 1807-1818
    • Martin-Rendon, E.1    Brunskill, S.J.2    Hyde, C.J.3    Stanworth, S.J.4    Mathur, A.5    Watt, S.M.6
  • 121
    • 35349008966 scopus 로고    scopus 로고
    • Impact of intracoronary cell therapy on left ventricular function in the setting of acute myocardial infarction: A collaborative systematic review and meta-analysis of controlled clinical trials
    • M. J. Lipinski, G. G. Biondi-Zoccai, A. Abbate et al., "Impact of intracoronary cell therapy on left ventricular function in the setting of acute myocardial infarction: a collaborative systematic review and meta-analysis of controlled clinical trials, " Journal of the American College of Cardiology, vol. 50, no. 18, pp. 1761-1767, 2007.
    • (2007) Journal of the American College of Cardiology , vol.50 , Issue.18 , pp. 1761-1767
    • Lipinski, M.J.1    Biondi-Zoccai, G.G.2    Abbate, A.3
  • 122
    • 33748899627 scopus 로고    scopus 로고
    • Intracoronary injection of mononuclear bone marrow cells in acute myocardial infarction
    • K. Lunde, S. Solheim, S. Aakhus et al., "Intracoronary injection of mononuclear bone marrow cells in acute myocardial infarction, " The New England Journal of Medicine, vol. 355, no. 12, pp. 1199-1209, 2006.
    • (2006) The New England Journal of Medicine , vol.355 , Issue.12 , pp. 1199-1209
    • Lunde, K.1    Solheim, S.2    Aakhus, S.3
  • 123
    • 30444432961 scopus 로고    scopus 로고
    • Autologous bone marrow-derived stem-cell transfer in patients with STsegment elevation myocardial infarction: Double-blind, randomised controlled trial
    • S. Janssens, C. Dubois, J. Bogaert et al., "Autologous bone marrow-derived stem-cell transfer in patients with STsegment elevation myocardial infarction: double-blind, randomised controlled trial, " The Lancet, vol. 367, no. 9505, pp. 113-121, 2006.
    • (2006) The Lancet , vol.367 , Issue.9505 , pp. 113-121
    • Janssens, S.1    Dubois, C.2    Bogaert, J.3
  • 125
    • 84876980723 scopus 로고    scopus 로고
    • FedExosomes: Engineering therapeutic biological nanoparticles that truly deliver
    • M. E. Marcus and J. N. Leonard, "FedExosomes: engineering therapeutic biological nanoparticles that truly deliver, " Pharmaceuticals (Basel), vol. 6, no. 5, pp. 659-680, 2013.
    • (2013) Pharmaceuticals (Basel) , vol.6 , Issue.5 , pp. 659-680
    • Marcus, M.E.1    Leonard, J.N.2
  • 126
    • 85016288110 scopus 로고    scopus 로고
    • Exosomes secreted by cardiosphere-derived cells reduce scarring, attenuate adverse remodelling, and improve function in acute and chronic porcine myocardial infarction
    • R. Gallet, J. Dawkins, J. Valle et al., "Exosomes secreted by cardiosphere-derived cells reduce scarring, attenuate adverse remodelling, and improve function in acute and chronic porcine myocardial infarction, " European Heart Journal, 2016.
    • (2016) European Heart Journal
    • Gallet, R.1    Dawkins, J.2    Valle, J.3
  • 127
    • 84899980641 scopus 로고    scopus 로고
    • Exosomes as critical agents of cardiac regeneration triggered by cell therapy
    • A. G. Ibrahim, K. Cheng, and E. Marban, "Exosomes as critical agents of cardiac regeneration triggered by cell therapy, " Stem Cell Reports, vol. 2, no. 5, pp. 606-619, 2014.
    • (2014) Stem Cell Reports , vol.2 , Issue.5 , pp. 606-619
    • Ibrahim, A.G.1    Cheng, K.2    Marban, E.3
  • 128
    • 84877116748 scopus 로고    scopus 로고
    • MicroRNA-146a is a therapeutic target and biomarker for peripartum cardiomyopathy
    • J. Halkein, S. P. Tabruyn, M. Ricke-Hoch et al., "MicroRNA-146a is a therapeutic target and biomarker for peripartum cardiomyopathy, " The Journal of Clinical Investigation, vol. 123, no. 5, pp. 2143-2154, 2013.
    • (2013) The Journal of Clinical Investigation , vol.123 , Issue.5 , pp. 2143-2154
    • Halkein, J.1    Tabruyn, S.P.2    Ricke-Hoch, M.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.