Y RNA fragment in extracellular vesicles confers cardioprotection via modulation of IL-10 expression and secretion

EMBO Molecular Medicine

Volumn 9, Issue 3, 2017, Pages 337-352

  Cambier, Linda ^a   de Couto, Geoffrey ^a   Ibrahim, Ahmed ^b   Echavez, Antonio K ^a   Valle, Jackelyn ^a   Liu, Weixin ^a   Kreke, Michelle ^b   Smith, Rachel R ^b   Marbán, Linda ^b   Marbán, Eduardo ^a  

^a CEDARS SINAI MEDICAL CENTER   (United States)

^b Capricor Inc   (United States)

Author keywords

extracellular vesicle; macrophage; RNA; stem cells

Indexed keywords

INTERLEUKIN 10; UNCLASSIFIED DRUG; UNTRANSLATED RNA; Y RNA FRAGMENT; SMALL CYTOPLASMIC RNA;

ADULT; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CHILD; CONTROLLED STUDY; CYTOKINE RELEASE; EXOSOME; FEMALE; HEART INFARCTION SIZE; HEART PROTECTION; HUMAN; HUMAN CELL; HUMAN TISSUE; MACROPHAGE; MALE; MIDDLE AGED; MYOCARDIAL ISCHEMIA REPERFUSION INJURY; NEWBORN; NONHUMAN; PRESCHOOL CHILD; PROTEIN EXPRESSION; RAT; SCHOOL CHILD; ANIMAL; CARDIAC MUSCLE CELL; CELL CULTURE; COCULTURE; DISEASE MODEL; IMMUNOLOGY; METABOLISM; MYOCARDIAL INFARCTION; SECRETION (PROCESS); TREATMENT OUTCOME; WISTAR RAT;

ANIMALS; CELLS, CULTURED; COCULTURE TECHNIQUES; DISEASE MODELS, ANIMAL; EXTRACELLULAR VESICLES; HUMANS; INTERLEUKIN-10; MACROPHAGES; MYOCARDIAL INFARCTION; MYOCYTES, CARDIAC; RATS, WISTAR; RNA, SMALL CYTOPLASMIC; TREATMENT OUTCOME;

EID: 85012302304     PISSN: 17574676     EISSN: 17574684     Source Type: Journal    
DOI: 10.15252/emmm.201606924     Document Type: Article

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