ERK8 is a novel HuR kinase that regulates tumour suppressor PDCD4 through a miR-21 dependent mechanism

Oncotarget

Volumn 7, Issue 2, 2016, Pages 1439-1450

  Liwak Muir, Urszula ^a   Dobson, Christine C ^a   Naing, Thet ^a   Wylie, Quinlan ^a   Chehade, Lucia ^a   Baird, Stephen D ^a   Chakraborty, Pranesh K ^a,b   Holcik, Martin ^a,b  

^a CHILDREN S HOSPITAL OF EASTERN ONTARIO   (Canada)

^b UNIVERSITY OF OTTAWA   (Canada)

Author keywords

Kinase; MiRNA; Tumour supressor

Indexed keywords

EXTRACELLULAR SIGNAL REGULATED KINASE 8; HYDROGEN PEROXIDE; MESSENGER RNA; MICRORNA 21; MITOGEN ACTIVATED PROTEIN KINASE; PROGRAMMED CELL DEATH 4 PROTEIN; TUMOR SUPPRESSOR PROTEIN; UNCLASSIFIED DRUG; 3' UNTRANSLATED REGION; APOPTOSIS REGULATORY PROTEIN; ELAV LIKE PROTEIN 1; ELAVL1 PROTEIN, HUMAN; MAPK15 PROTEIN, HUMAN; MICRORNA; MIRN21 MICRORNA, HUMAN; PDCD4 PROTEIN, HUMAN; RNA BINDING PROTEIN;

3' UNTRANSLATED REGION; ARTICLE; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME PHOSPHORYLATION; GENE SILENCING; PROTEIN DEGRADATION; PROTEIN EXPRESSION; RNA BINDING; RNA STABILITY; BINDING SITE; DRUG EFFECTS; ENZYME ACTIVATION; ENZYMOLOGY; FEMALE; GENE EXPRESSION REGULATION; GENETIC TRANSFECTION; GENETICS; HELA CELL LINE; HUMAN; METABOLISM; PATHOLOGY; PHOSPHORYLATION; RNA INTERFERENCE; SIGNAL TRANSDUCTION; TIME FACTOR; UTERINE CERVIX TUMOR;

3' UNTRANSLATED REGIONS; APOPTOSIS REGULATORY PROTEINS; BINDING SITES; ELAV-LIKE PROTEIN 1; ENZYME ACTIVATION; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; FEMALE; GENE EXPRESSION REGULATION, NEOPLASTIC; GENE SILENCING; HELA CELLS; HUMANS; HYDROGEN PEROXIDE; MICRORNAS; PHOSPHORYLATION; RNA INTERFERENCE; RNA STABILITY; RNA, MESSENGER; RNA-BINDING PROTEINS; SIGNAL TRANSDUCTION; TIME FACTORS; TRANSFECTION; UTERINE CERVICAL NEOPLASMS;

EID: 84957631447     PISSN: None     EISSN: 19492553     Source Type: Journal    
DOI: 10.18632/oncotarget.6363     Document Type: Article

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