메뉴 건너뛰기




Volumn 281, Issue 1, 2018, Pages 154-168

Interleukin-33 (IL-33): A nuclear cytokine from the IL-1 family

Author keywords

allergy; cytokine; IL 33; ILC2; inflammation; innate immunity

Indexed keywords

INTERLEUKIN 1 RECEPTOR LIKE 1 PROTEIN; INTERLEUKIN 33; PROTEINASE; IL1RL1 PROTEIN, HUMAN; IL33 PROTEIN, HUMAN; INTERLEUKIN 1;

EID: 85038022428     PISSN: 01052896     EISSN: 1600065X     Source Type: Journal    
DOI: 10.1111/imr.12619     Document Type: Review
Times cited : (631)

References (149)
  • 1
    • 84920950343 scopus 로고    scopus 로고
    • IL-33: An alarmin cytokine with crucial roles in innate immunity, inflammation and allergy
    • Cayrol C, Girard JP. IL-33: An alarmin cytokine with crucial roles in innate immunity, inflammation and allergy. Curr Opin Immunol. 2014;31C:31-37.
    • (2014) Curr Opin Immunol , vol.31C , pp. 31-37
    • Cayrol, C.1    Girard, J.P.2
  • 2
    • 84937557838 scopus 로고    scopus 로고
    • Interleukin-33 in tissue homeostasis, injury, and inflammation
    • Molofsky AB, Savage AK, Locksley RM. Interleukin-33 in tissue homeostasis, injury, and inflammation. Immunity. 2015;42:1005-1019.
    • (2015) Immunity , vol.42 , pp. 1005-1019
    • Molofsky, A.B.1    Savage, A.K.2    Locksley, R.M.3
  • 4
    • 75749122181 scopus 로고    scopus 로고
    • Innate production of T(H)2 cytokines by adipose tissue-associated c-Kit(+)Sca-1(+) lymphoid cells
    • Moro K, Yamada T, Tanabe M, et al. Innate production of T(H)2 cytokines by adipose tissue-associated c-Kit(+)Sca-1(+) lymphoid cells. Nature. 2010;463:540-544.
    • (2010) Nature , vol.463 , pp. 540-544
    • Moro, K.1    Yamada, T.2    Tanabe, M.3
  • 5
    • 77951817855 scopus 로고    scopus 로고
    • Nuocytes represent a new innate effector leukocyte that mediates type-2 immunity
    • Neill DR, Wong SH, Bellosi A, et al. Nuocytes represent a new innate effector leukocyte that mediates type-2 immunity. Nature. 2010;464:1367-1370.
    • (2010) Nature , vol.464 , pp. 1367-1370
    • Neill, D.R.1    Wong, S.H.2    Bellosi, A.3
  • 6
    • 77954926597 scopus 로고    scopus 로고
    • Systemically dispersed innate IL-13-expressing cells in type 2 immunity
    • Price AE, Liang HE, Sullivan BM, et al. Systemically dispersed innate IL-13-expressing cells in type 2 immunity. Proc Natl Acad Sci USA. 2010;107:11489-11494.
    • (2010) Proc Natl Acad Sci USA , vol.107 , pp. 11489-11494
    • Price, A.E.1    Liang, H.E.2    Sullivan, B.M.3
  • 7
    • 80054889051 scopus 로고    scopus 로고
    • Human IL-25- and IL-33-responsive type 2 innate lymphoid cells are defined by expression of CRTH2 and CD161
    • Mjosberg JM, Trifari S, Crellin NK, et al. Human IL-25- and IL-33-responsive type 2 innate lymphoid cells are defined by expression of CRTH2 and CD161. Nat Immunol. 2011;12:1055-1062.
    • (2011) Nat Immunol , vol.12 , pp. 1055-1062
    • Mjosberg, J.M.1    Trifari, S.2    Crellin, N.K.3
  • 8
    • 84885572626 scopus 로고    scopus 로고
    • Type 2 innate lymphoid cells control eosinophil homeostasis
    • Nussbaum JC, Van Dyken SJ, von Moltke J, et al. Type 2 innate lymphoid cells control eosinophil homeostasis. Nature. 2013;502:245-248.
    • (2013) Nature , vol.502 , pp. 245-248
    • Nussbaum, J.C.1    Van Dyken, S.J.2    von Moltke, J.3
  • 9
    • 84922607138 scopus 로고    scopus 로고
    • The biology of innate lymphoid cells
    • Artis D, Spits H. The biology of innate lymphoid cells. Nature. 2015;517:293-301.
    • (2015) Nature , vol.517 , pp. 293-301
    • Artis, D.1    Spits, H.2
  • 10
    • 84929996266 scopus 로고    scopus 로고
    • Innate lymphoid cells. Innate lymphoid cells: A new paradigm in immunology
    • Eberl G, Colonna M, Di SJ, McKenzie AN. Innate lymphoid cells. Innate lymphoid cells: A new paradigm in immunology. Science. 2015;348:aaa6566.
    • (2015) Science , vol.348 , pp. aaa6566
    • Eberl, G.1    Colonna, M.2    Di, S.J.3    McKenzie, A.N.4
  • 11
    • 84875231964 scopus 로고    scopus 로고
    • Decoding asthma: Translating genetic variation in IL33 and IL1RL1 into disease pathophysiology
    • Grotenboer NS, Ketelaar ME, Koppelman GH, Nawijn MC. Decoding asthma: Translating genetic variation in IL33 and IL1RL1 into disease pathophysiology. J Allergy Clin Immunol. 2013;131:856-865.
    • (2013) J Allergy Clin Immunol , vol.131 , pp. 856-865
    • Grotenboer, N.S.1    Ketelaar, M.E.2    Koppelman, G.H.3    Nawijn, M.C.4
  • 12
    • 84871973438 scopus 로고    scopus 로고
    • Genome-wide association studies in asthma: What they really told us about pathogenesis
    • Wjst M, Sargurupremraj M, Arnold M. Genome-wide association studies in asthma: What they really told us about pathogenesis. Curr Opin Allergy Clin Immunol. 2013;13:112-118.
    • (2013) Curr Opin Allergy Clin Immunol , vol.13 , pp. 112-118
    • Wjst, M.1    Sargurupremraj, M.2    Arnold, M.3
  • 13
    • 61349089164 scopus 로고    scopus 로고
    • Sequence variants affecting eosinophil numbers associate with asthma and myocardial infarction
    • Gudbjartsson DF, Bjornsdottir US, Halapi E, et al. Sequence variants affecting eosinophil numbers associate with asthma and myocardial infarction. Nat Genet. 2009;41:342-347.
    • (2009) Nat Genet , vol.41 , pp. 342-347
    • Gudbjartsson, D.F.1    Bjornsdottir, U.S.2    Halapi, E.3
  • 14
    • 77957113600 scopus 로고    scopus 로고
    • A large-scale, consortium-based genomewide association study of asthma
    • Moffatt MF, Gut IG, Demenais F, et al. A large-scale, consortium-based genomewide association study of asthma. N Engl J Med. 2010;363:1211-1221.
    • (2010) N Engl J Med , vol.363 , pp. 1211-1221
    • Moffatt, M.F.1    Gut, I.G.2    Demenais, F.3
  • 15
    • 80052259316 scopus 로고    scopus 로고
    • Meta-analysis of genome-wide association studies of asthma in ethnically diverse North American populations
    • Torgerson DG, Ampleford EJ, Chiu GY, et al. Meta-analysis of genome-wide association studies of asthma in ethnically diverse North American populations. Nat Genet. 2011;43:887-892.
    • (2011) Nat Genet , vol.43 , pp. 887-892
    • Torgerson, D.G.1    Ampleford, E.J.2    Chiu, G.Y.3
  • 16
    • 84866995093 scopus 로고    scopus 로고
    • Genome-wide association studies of asthma in population-based cohorts confirm known and suggested loci and identify an additional association near HLA
    • Ramasamy A, Kuokkanen M, Vedantam S, et al. Genome-wide association studies of asthma in population-based cohorts confirm known and suggested loci and identify an additional association near HLA. PLoS ONE. 2012;7:e44008.
    • (2012) PLoS ONE , vol.7
    • Ramasamy, A.1    Kuokkanen, M.2    Vedantam, S.3
  • 17
    • 84891372721 scopus 로고    scopus 로고
    • A genome-wide association study identifies CDHR3 as a susceptibility locus for early childhood asthma with severe exacerbations
    • Bonnelykke K, Sleiman P, Nielsen K, et al. A genome-wide association study identifies CDHR3 as a susceptibility locus for early childhood asthma with severe exacerbations. Nat Genet. 2014;46:51-55.
    • (2014) Nat Genet , vol.46 , pp. 51-55
    • Bonnelykke, K.1    Sleiman, P.2    Nielsen, K.3
  • 18
    • 48449089903 scopus 로고    scopus 로고
    • IL-33 amplifies both Th1- and Th2-type responses through its activity on human basophils, allergen-reactive Th2 cells, iNKT and NK cells
    • Smithgall MD, Comeau MR, Yoon BR, Kaufman D, Armitage R, Smith DE. IL-33 amplifies both Th1- and Th2-type responses through its activity on human basophils, allergen-reactive Th2 cells, iNKT and NK cells. Int Immunol. 2008;20:1019-1030.
    • (2008) Int Immunol , vol.20 , pp. 1019-1030
    • Smithgall, M.D.1    Comeau, M.R.2    Yoon, B.R.3    Kaufman, D.4    Armitage, R.5    Smith, D.E.6
  • 19
    • 65449146468 scopus 로고    scopus 로고
    • The pro-Th2 cytokine IL-33 directly interacts with invariant NKT and NK cells to induce IFN-gamma production
    • Bourgeois E, Van LP, Samson M, et al. The pro-Th2 cytokine IL-33 directly interacts with invariant NKT and NK cells to induce IFN-gamma production. Eur J Immunol. 2009;39:1046-1055.
    • (2009) Eur J Immunol , vol.39 , pp. 1046-1055
    • Bourgeois, E.1    Van, L.P.2    Samson, M.3
  • 20
    • 84857640602 scopus 로고    scopus 로고
    • The alarmin interleukin-33 drives protective antiviral CD8 T cell responses
    • Bonilla WV, Frohlich A, Senn K, et al. The alarmin interleukin-33 drives protective antiviral CD8 T cell responses. Science. 2012;335:984-989.
    • (2012) Science , vol.335 , pp. 984-989
    • Bonilla, W.V.1    Frohlich, A.2    Senn, K.3
  • 21
    • 84924981783 scopus 로고    scopus 로고
    • Cigarette smoke silences innate lymphoid cell function and facilitates an exacerbated type I interleukin-33-dependent response to infection
    • Kearley J, Silver JS, Sanden C, et al. Cigarette smoke silences innate lymphoid cell function and facilitates an exacerbated type I interleukin-33-dependent response to infection. Immunity. 2015;42:566-579.
    • (2015) Immunity , vol.42 , pp. 566-579
    • Kearley, J.1    Silver, J.S.2    Sanden, C.3
  • 22
    • 84962033988 scopus 로고    scopus 로고
    • IL-33 in T cell differentiation, function, and immune homeostasis
    • Peine M, Marek RM, Lohning M. IL-33 in T cell differentiation, function, and immune homeostasis. Trends Immunol. 2016;37:321-333.
    • (2016) Trends Immunol , vol.37 , pp. 321-333
    • Peine, M.1    Marek, R.M.2    Lohning, M.3
  • 23
    • 80555126115 scopus 로고    scopus 로고
    • IL-33 expands suppressive CD11b+ Gr-1(int) and regulatory T cells, including ST2L+ Foxp3+ cells, and mediates regulatory T cell-dependent promotion of cardiac allograft survival
    • Turnquist HR, Zhao Z, Rosborough BR, et al. IL-33 expands suppressive CD11b+ Gr-1(int) and regulatory T cells, including ST2L+ Foxp3+ cells, and mediates regulatory T cell-dependent promotion of cardiac allograft survival. J Immunol. 2011;187:4598-4610.
    • (2011) J Immunol , vol.187 , pp. 4598-4610
    • Turnquist, H.R.1    Zhao, Z.2    Rosborough, B.R.3
  • 24
    • 85014943621 scopus 로고    scopus 로고
    • Peri-alloHCT IL-33 administration expands recipient T regulatory cells that protect mice against acute GVHD
    • Matta BM, Reichenbach DK, Zhang X, et al. Peri-alloHCT IL-33 administration expands recipient T regulatory cells that protect mice against acute GVHD. Blood. 2016;128:427-439.
    • (2016) Blood , vol.128 , pp. 427-439
    • Matta, B.M.1    Reichenbach, D.K.2    Zhang, X.3
  • 25
    • 84906571227 scopus 로고    scopus 로고
    • The alarmin IL-33 promotes regulatory T-cell function in the intestine
    • Schiering C, Krausgruber T, Chomka A, et al. The alarmin IL-33 promotes regulatory T-cell function in the intestine. Nature. 2014;513:564-568.
    • (2014) Nature , vol.513 , pp. 564-568
    • Schiering, C.1    Krausgruber, T.2    Chomka, A.3
  • 26
    • 84940380928 scopus 로고    scopus 로고
    • A distinct function of regulatory T cells in tissue protection
    • Arpaia N, Green JA, Moltedo B, et al. A distinct function of regulatory T cells in tissue protection. Cell. 2015;162:1078-1089.
    • (2015) Cell , vol.162 , pp. 1078-1089
    • Arpaia, N.1    Green, J.A.2    Moltedo, B.3
  • 27
    • 84928407438 scopus 로고    scopus 로고
    • Antigen- and cytokine-driven accumulation of regulatory T cells in visceral adipose tissue of lean mice
    • Kolodin D, van Panhuys N, Li C, et al. Antigen- and cytokine-driven accumulation of regulatory T cells in visceral adipose tissue of lean mice. Cell Metab. 2015;21:543-557.
    • (2015) Cell Metab , vol.21 , pp. 543-557
    • Kolodin, D.1    van Panhuys, N.2    Li, C.3
  • 28
    • 84923607143 scopus 로고    scopus 로고
    • The transcriptional regulators IRF4, BATF and IL-33 orchestrate development and maintenance of adipose tissue-resident regulatory T cells
    • Vasanthakumar A, Moro K, Xin A, et al. The transcriptional regulators IRF4, BATF and IL-33 orchestrate development and maintenance of adipose tissue-resident regulatory T cells. Nat Immunol. 2015;16:276-285.
    • (2015) Nat Immunol , vol.16 , pp. 276-285
    • Vasanthakumar, A.1    Moro, K.2    Xin, A.3
  • 29
    • 84937618997 scopus 로고    scopus 로고
    • Interleukin-33 and interferon-gamma counter-regulate group 2 innate lymphoid cell activation during immune perturbation
    • Molofsky AB, Van Gool F, Liang HE, et al. Interleukin-33 and interferon-gamma counter-regulate group 2 innate lymphoid cell activation during immune perturbation. Immunity. 2015;43:161-174.
    • (2015) Immunity , vol.43 , pp. 161-174
    • Molofsky, A.B.1    Van Gool, F.2    Liang, H.E.3
  • 30
    • 85027948313 scopus 로고    scopus 로고
    • Innate lymphoid cells promote lung-tissue homeostasis after infection with influenza virus
    • Monticelli LA, Sonnenberg GF, Abt MC, et al. Innate lymphoid cells promote lung-tissue homeostasis after infection with influenza virus. Nat Immunol. 2011;12:1045-1054.
    • (2011) Nat Immunol , vol.12 , pp. 1045-1054
    • Monticelli, L.A.1    Sonnenberg, G.F.2    Abt, M.C.3
  • 31
    • 0037631696 scopus 로고    scopus 로고
    • Molecular characterization of NF-HEV, a nuclear factor preferentially expressed in human high endothelial venules
    • Baekkevold ES, Roussigne M, Yamanaka T, et al. Molecular characterization of NF-HEV, a nuclear factor preferentially expressed in human high endothelial venules. Am J Pathol. 2003;163:69-79.
    • (2003) Am J Pathol , vol.163 , pp. 69-79
    • Baekkevold, E.S.1    Roussigne, M.2    Yamanaka, T.3
  • 32
    • 84867900263 scopus 로고    scopus 로고
    • HEVs, lymphatics and homeostatic immune cell trafficking in lymph nodes
    • Girard JP, Moussion C, Forster R. HEVs, lymphatics and homeostatic immune cell trafficking in lymph nodes. Nat Rev Immunol. 2012;12:762-773.
    • (2012) Nat Rev Immunol , vol.12 , pp. 762-773
    • Girard, J.P.1    Moussion, C.2    Forster, R.3
  • 33
    • 81855203183 scopus 로고    scopus 로고
    • Dendritic cells control lymphocyte entry to lymph nodes through high endothelial venules
    • Moussion C, Girard JP. Dendritic cells control lymphocyte entry to lymph nodes through high endothelial venules. Nature. 2011;479:542-546.
    • (2011) Nature , vol.479 , pp. 542-546
    • Moussion, C.1    Girard, J.P.2
  • 34
    • 0033510084 scopus 로고    scopus 로고
    • Identification of genes differentially expressed in canine vasospastic cerebral arteries after subarachnoid hemorrhage
    • Onda H, Kasuya H, Takakura K, et al. Identification of genes differentially expressed in canine vasospastic cerebral arteries after subarachnoid hemorrhage. J Cereb Blood Flow Metab. 1999;19:1279-1288.
    • (1999) J Cereb Blood Flow Metab , vol.19 , pp. 1279-1288
    • Onda, H.1    Kasuya, H.2    Takakura, K.3
  • 35
    • 27744446058 scopus 로고    scopus 로고
    • IL-33, an interleukin-1-like cytokine that signals via the IL-1 receptor-related protein ST2 and induces T helper type 2-associated cytokines
    • Schmitz J, Owyang A, Oldham E, et al. IL-33, an interleukin-1-like cytokine that signals via the IL-1 receptor-related protein ST2 and induces T helper type 2-associated cytokines. Immunity. 2005;23:479-490.
    • (2005) Immunity , vol.23 , pp. 479-490
    • Schmitz, J.1    Owyang, A.2    Oldham, E.3
  • 36
    • 33846101552 scopus 로고    scopus 로고
    • IL-33, the IL-1-like cytokine ligand for ST2 receptor, is a chromatin-associated nuclear factor in vivo
    • Carriere V, Roussel L, Ortega N, et al. IL-33, the IL-1-like cytokine ligand for ST2 receptor, is a chromatin-associated nuclear factor in vivo. Proc Natl Acad Sci USA. 2007;104:282-287.
    • (2007) Proc Natl Acad Sci USA , vol.104 , pp. 282-287
    • Carriere, V.1    Roussel, L.2    Ortega, N.3
  • 37
    • 85007545513 scopus 로고    scopus 로고
    • Identification of the promoter region of human IL-33 responsive to induction by IFNgamma
    • Tsuda H, Komine M, Tominaga SI, Ohtsuki M. Identification of the promoter region of human IL-33 responsive to induction by IFNgamma. J Dermatol Sci. 2017;85:137-140.
    • (2017) J Dermatol Sci , vol.85 , pp. 137-140
    • Tsuda, H.1    Komine, M.2    Tominaga, S.I.3    Ohtsuki, M.4
  • 38
    • 84855315570 scopus 로고    scopus 로고
    • The mouse interleukin (Il)33 gene is expressed in a cell type- and stimulus-dependent manner from two alternative promoters
    • Talabot-Ayer D, Calo N, Vigne S, Lamacchia C, Gabay C, Palmer G. The mouse interleukin (Il)33 gene is expressed in a cell type- and stimulus-dependent manner from two alternative promoters. J Leukoc Biol. 2012;91:119-125.
    • (2012) J Leukoc Biol , vol.91 , pp. 119-125
    • Talabot-Ayer, D.1    Calo, N.2    Vigne, S.3    Lamacchia, C.4    Gabay, C.5    Palmer, G.6
  • 39
    • 85016564329 scopus 로고    scopus 로고
    • A rare IL33 loss-of-function mutation reduces blood eosinophil counts and protects from asthma
    • Smith D, Helgason H, Sulem P, et al. A rare IL33 loss-of-function mutation reduces blood eosinophil counts and protects from asthma. PLoS Genet. 2017;13:e1006659.
    • (2017) PLoS Genet , vol.13
    • Smith, D.1    Helgason, H.2    Sulem, P.3
  • 40
    • 84867893281 scopus 로고    scopus 로고
    • Novel splice variants of IL-33: Differential expression in normal and transformed cells
    • Tsuda H, Komine M, Karakawa M, Etoh T, Tominaga S, Ohtsuki M. Novel splice variants of IL-33: Differential expression in normal and transformed cells. J Invest Dermatol. 2012;132:2661-2664.
    • (2012) J Invest Dermatol , vol.132 , pp. 2661-2664
    • Tsuda, H.1    Komine, M.2    Karakawa, M.3    Etoh, T.4    Tominaga, S.5    Ohtsuki, M.6
  • 41
    • 79957595391 scopus 로고    scopus 로고
    • Identification of constitutively active interleukin 33 (IL-33) splice variant
    • Hong J, Bae S, Jhun H, et al. Identification of constitutively active interleukin 33 (IL-33) splice variant. J Biol Chem. 2011;286:20078-20086.
    • (2011) J Biol Chem , vol.286 , pp. 20078-20086
    • Hong, J.1    Bae, S.2    Jhun, H.3
  • 42
    • 84982684032 scopus 로고    scopus 로고
    • Alternative splicing of interleukin-33 and type 2 inflammation in asthma
    • Gordon ED, Simpson LJ, Rios CL, et al. Alternative splicing of interleukin-33 and type 2 inflammation in asthma. Proc Natl Acad Sci USA. 2016;113:8765-8770.
    • (2016) Proc Natl Acad Sci USA , vol.113 , pp. 8765-8770
    • Gordon, E.D.1    Simpson, L.J.2    Rios, C.L.3
  • 43
    • 53249093714 scopus 로고    scopus 로고
    • Molecular mimicry between IL-33 and KSHV for attachment to chromatin through the H2A-H2B acidic pocket
    • Roussel L, Erard M, Cayrol C, Girard JP. Molecular mimicry between IL-33 and KSHV for attachment to chromatin through the H2A-H2B acidic pocket. EMBO Rep. 2008;9:1006-1012.
    • (2008) EMBO Rep , vol.9 , pp. 1006-1012
    • Roussel, L.1    Erard, M.2    Cayrol, C.3    Girard, J.P.4
  • 44
    • 84922404569 scopus 로고    scopus 로고
    • Altered subcellular localization of IL-33 leads to non-resolving lethal inflammation
    • Bessa J, Meyer CA, de Vera Mudry MC, et al. Altered subcellular localization of IL-33 leads to non-resolving lethal inflammation. J Autoimmun. 2014;55:33-41.
    • (2014) J Autoimmun , vol.55 , pp. 33-41
    • Bessa, J.1    Meyer, C.A.2    de Vera Mudry, M.C.3
  • 45
    • 84961158652 scopus 로고    scopus 로고
    • IL-33 amplifies an innate immune response in the degenerating retina
    • Xi H, Katschke KJ Jr, Li Y, et al. IL-33 amplifies an innate immune response in the degenerating retina. J Exp Med. 2016;213:189-207.
    • (2016) J Exp Med , vol.213 , pp. 189-207
    • Xi, H.1    Katschke, K.J.2    Li, Y.3
  • 46
    • 32444439636 scopus 로고    scopus 로고
    • The nucleosomal surface as a docking station for Kaposi's sarcoma herpesvirus LANA
    • Barbera AJ, Chodaparambil JV, Kelley-Clarke B, et al. The nucleosomal surface as a docking station for Kaposi's sarcoma herpesvirus LANA. Science. 2006;311:856-861.
    • (2006) Science , vol.311 , pp. 856-861
    • Barbera, A.J.1    Chodaparambil, J.V.2    Kelley-Clarke, B.3
  • 47
    • 70349759672 scopus 로고    scopus 로고
    • Structure of IL-33 and its interaction with the ST2 and IL-1RAcP receptors–insight into heterotrimeric IL-1 signaling complexes
    • Lingel A, Weiss TM, Niebuhr M, et al. Structure of IL-33 and its interaction with the ST2 and IL-1RAcP receptors–insight into heterotrimeric IL-1 signaling complexes. Structure. 2009;17:1398-1410.
    • (2009) Structure , vol.17 , pp. 1398-1410
    • Lingel, A.1    Weiss, T.M.2    Niebuhr, M.3
  • 48
    • 84883815093 scopus 로고    scopus 로고
    • Structural insights into the interaction of IL-33 with its receptors
    • Liu X, Hammel M, He Y, et al. Structural insights into the interaction of IL-33 with its receptors. Proc Natl Acad Sci U S A. 2013;110:14918-14923.
    • (2013) Proc Natl Acad Sci U S A , vol.110 , pp. 14918-14923
    • Liu, X.1    Hammel, M.2    He, Y.3
  • 50
    • 49449111630 scopus 로고    scopus 로고
    • IL-33 exacerbates antigen-induced arthritis by activating mast cells
    • Xu D, Jiang HR, Kewin P, et al. IL-33 exacerbates antigen-induced arthritis by activating mast cells. Proc Natl Acad Sci USA. 2008;105:10913-10918.
    • (2008) Proc Natl Acad Sci USA , vol.105 , pp. 10913-10918
    • Xu, D.1    Jiang, H.R.2    Kewin, P.3
  • 51
    • 84937697152 scopus 로고    scopus 로고
    • An interleukin-33-mast cell-interleukin-2 axis suppresses papain-induced allergic inflammation by promoting regulatory T cell numbers
    • Morita H, Arae K, Unno H, et al. An interleukin-33-mast cell-interleukin-2 axis suppresses papain-induced allergic inflammation by promoting regulatory T cell numbers. Immunity. 2015;43:175-186.
    • (2015) Immunity , vol.43 , pp. 175-186
    • Morita, H.1    Arae, K.2    Unno, H.3
  • 52
    • 84929191609 scopus 로고    scopus 로고
    • IL-33 activates tumor stroma to promote intestinal polyposis
    • Maywald RL, Doerner SK, Pastorelli L, et al. IL-33 activates tumor stroma to promote intestinal polyposis. Proc Natl Acad Sci USA. 2015;112:E2487-E2496.
    • (2015) Proc Natl Acad Sci USA , vol.112 , pp. E2487-E2496
    • Maywald, R.L.1    Doerner, S.K.2    Pastorelli, L.3
  • 53
    • 84924988052 scopus 로고    scopus 로고
    • The glia-derived alarmin IL-33 orchestrates the immune response and promotes recovery following CNS injury
    • Gadani SP, Walsh JT, Smirnov I, Zheng J, Kipnis J. The glia-derived alarmin IL-33 orchestrates the immune response and promotes recovery following CNS injury. Neuron. 2015;85:703-709.
    • (2015) Neuron , vol.85 , pp. 703-709
    • Gadani, S.P.1    Walsh, J.T.2    Smirnov, I.3    Zheng, J.4    Kipnis, J.5
  • 54
    • 84966659702 scopus 로고    scopus 로고
    • Programming of intestinal epithelial differentiation by IL-33 derived from pericryptal fibroblasts in response to systemic infection
    • Mahapatro M, Foersch S, Hefele M, et al. Programming of intestinal epithelial differentiation by IL-33 derived from pericryptal fibroblasts in response to systemic infection. Cell Rep. 2016;15:1743-1756.
    • (2016) Cell Rep , vol.15 , pp. 1743-1756
    • Mahapatro, M.1    Foersch, S.2    Hefele, M.3
  • 55
    • 84989844280 scopus 로고    scopus 로고
    • Extracellular IL-33 cytokine, but not endogenous nuclear IL-33, regulates protein expression in endothelial cells
    • Gautier V, Cayrol C, Farache D, et al. Extracellular IL-33 cytokine, but not endogenous nuclear IL-33, regulates protein expression in endothelial cells. Sci Rep. 2016;6:34255.
    • (2016) Sci Rep , vol.6 , pp. 34255
    • Gautier, V.1    Cayrol, C.2    Farache, D.3
  • 56
    • 84996563530 scopus 로고    scopus 로고
    • IL-33/ST2 signaling excites sensory neurons and mediates itch response in a mouse model of poison ivy contact allergy
    • Liu B, Tai Y, Achanta S, et al. IL-33/ST2 signaling excites sensory neurons and mediates itch response in a mouse model of poison ivy contact allergy. Proc Natl Acad Sci USA. 2016;113:E7572-E7579.
    • (2016) Proc Natl Acad Sci USA , vol.113 , pp. E7572-E7579
    • Liu, B.1    Tai, Y.2    Achanta, S.3
  • 57
    • 53749093767 scopus 로고    scopus 로고
    • The IL-1-like cytokine IL-33 is constitutively expressed in the nucleus of endothelial cells and epithelial cells in vivo: A novel ‘alarmin’?
    • Moussion C, Ortega N, Girard JP. The IL-1-like cytokine IL-33 is constitutively expressed in the nucleus of endothelial cells and epithelial cells in vivo: A novel ‘alarmin’? PLoS ONE. 2008;3:e3331.
    • (2008) PLoS ONE , vol.3
    • Moussion, C.1    Ortega, N.2    Girard, J.P.3
  • 58
    • 84859378165 scopus 로고    scopus 로고
    • Endogenous IL-33 is highly expressed in mouse epithelial barrier tissues, lymphoid organs, brain, embryos, and inflamed tissues. In situ analysis using a novel Il-33-LacZ gene trap reporter strain
    • Pichery M, Mirey E, Mercier P, et al. Endogenous IL-33 is highly expressed in mouse epithelial barrier tissues, lymphoid organs, brain, embryos, and inflamed tissues. In situ analysis using a novel Il-33-LacZ gene trap reporter strain. J Immunol. 2012;188:3488-3495.
    • (2012) J Immunol , vol.188 , pp. 3488-3495
    • Pichery, M.1    Mirey, E.2    Mercier, P.3
  • 59
    • 84931259787 scopus 로고    scopus 로고
    • Myocardial pressure overload induces systemic inflammation through endothelial cell IL-33
    • Chen WY, Hong J, Gannon J, Kakkar R, Lee RT. Myocardial pressure overload induces systemic inflammation through endothelial cell IL-33. Proc Natl Acad Sci USA. 2015;112:7249-7254.
    • (2015) Proc Natl Acad Sci USA , vol.112 , pp. 7249-7254
    • Chen, W.Y.1    Hong, J.2    Gannon, J.3    Kakkar, R.4    Lee, R.T.5
  • 61
    • 84857768885 scopus 로고    scopus 로고
    • Contribution of IL-33-activated type II innate lymphoid cells to pulmonary eosinophilia in intestinal nematode-infected mice
    • Yasuda K, Muto T, Kawagoe T, et al. Contribution of IL-33-activated type II innate lymphoid cells to pulmonary eosinophilia in intestinal nematode-infected mice. Proc Natl Acad Sci USA. 2012;109:3451-3456.
    • (2012) Proc Natl Acad Sci USA , vol.109 , pp. 3451-3456
    • Yasuda, K.1    Muto, T.2    Kawagoe, T.3
  • 62
    • 79955509396 scopus 로고    scopus 로고
    • Endogenous IL-33 enhances Th2 cytokine production and T-cell responses during allergic airway inflammation
    • Louten J, Rankin AL, Li Y, et al. Endogenous IL-33 enhances Th2 cytokine production and T-cell responses during allergic airway inflammation. Int Immunol. 2011;23:307-315.
    • (2011) Int Immunol , vol.23 , pp. 307-315
    • Louten, J.1    Rankin, A.L.2    Li, Y.3
  • 63
    • 84857484469 scopus 로고    scopus 로고
    • Interleukin 33 as a mechanically responsive cytokine secreted by living cells
    • Kakkar R, Hei H, Dobner S, Lee RT. Interleukin 33 as a mechanically responsive cytokine secreted by living cells. J Biol Chem. 2012;287:6941-6948.
    • (2012) J Biol Chem , vol.287 , pp. 6941-6948
    • Kakkar, R.1    Hei, H.2    Dobner, S.3    Lee, R.T.4
  • 64
    • 84941686678 scopus 로고    scopus 로고
    • Oxidation of the alarmin IL-33 regulates ST2-dependent inflammation
    • Cohen ES, Scott IC, Majithiya JB, et al. Oxidation of the alarmin IL-33 regulates ST2-dependent inflammation. Nat Commun. 2015;6:8327.
    • (2015) Nat Commun , vol.6 , pp. 8327
    • Cohen, E.S.1    Scott, I.C.2    Majithiya, J.B.3
  • 65
    • 80051926552 scopus 로고    scopus 로고
    • The dual function cytokine IL-33 interacts with the transcription factor NF-kappaB to dampen NF-kappaB-stimulated gene transcription
    • Ali S, Mohs A, Thomas M, et al. The dual function cytokine IL-33 interacts with the transcription factor NF-kappaB to dampen NF-kappaB-stimulated gene transcription. J Immunol. 2011;187:1609-1616.
    • (2011) J Immunol , vol.187 , pp. 1609-1616
    • Ali, S.1    Mohs, A.2    Thomas, M.3
  • 66
    • 62649139025 scopus 로고    scopus 로고
    • Immunological and inflammatory functions of the interleukin-1 family
    • Dinarello CA. Immunological and inflammatory functions of the interleukin-1 family. Annu Rev Immunol. 2009;27:519-550.
    • (2009) Annu Rev Immunol , vol.27 , pp. 519-550
    • Dinarello, C.A.1
  • 67
    • 67049158193 scopus 로고    scopus 로고
    • The IL-1-like cytokine IL-33 is inactivated after maturation by caspase-1
    • Cayrol C, Girard JP. The IL-1-like cytokine IL-33 is inactivated after maturation by caspase-1. Proc Natl Acad Sci USA. 2009;106:9021-9026.
    • (2009) Proc Natl Acad Sci USA , vol.106 , pp. 9021-9026
    • Cayrol, C.1    Girard, J.P.2
  • 68
    • 68249137289 scopus 로고    scopus 로고
    • Suppression of interleukin-33 bioactivity through proteolysis by apoptotic caspases
    • Luthi AU, Cullen SP, McNeela EA, et al. Suppression of interleukin-33 bioactivity through proteolysis by apoptotic caspases. Immunity. 2009;31:84-98.
    • (2009) Immunity , vol.31 , pp. 84-98
    • Luthi, A.U.1    Cullen, S.P.2    McNeela, E.A.3
  • 69
    • 67651053209 scopus 로고    scopus 로고
    • Interleukin-33 is biologically active independently of caspase-1 cleavage
    • Talabot-Ayer D, Lamacchia C, Gabay C, Palmer G. Interleukin-33 is biologically active independently of caspase-1 cleavage. J Biol Chem. 2009;284:19420-19426.
    • (2009) J Biol Chem , vol.284 , pp. 19420-19426
    • Talabot-Ayer, D.1    Lamacchia, C.2    Gabay, C.3    Palmer, G.4
  • 70
    • 84857134135 scopus 로고    scopus 로고
    • IL-33 is processed into mature bioactive forms by neutrophil elastase and cathepsin G
    • Lefrancais E, Roga S, Gautier V, et al. IL-33 is processed into mature bioactive forms by neutrophil elastase and cathepsin G. Proc Natl Acad Sci USA. 2012;109:1673-1678.
    • (2012) Proc Natl Acad Sci USA , vol.109 , pp. 1673-1678
    • Lefrancais, E.1    Roga, S.2    Gautier, V.3
  • 71
    • 84908541933 scopus 로고    scopus 로고
    • Central domain of IL-33 is cleaved by mast cell proteases for potent activation of group-2 innate lymphoid cells
    • Lefrancais E, Duval A, Mirey E, et al. Central domain of IL-33 is cleaved by mast cell proteases for potent activation of group-2 innate lymphoid cells. Proc Natl Acad Sci USA. 2014;111:15502-15507.
    • (2014) Proc Natl Acad Sci USA , vol.111 , pp. 15502-15507
    • Lefrancais, E.1    Duval, A.2    Mirey, E.3
  • 72
    • 85017372490 scopus 로고    scopus 로고
    • Oxidative stress serves as a key checkpoint for IL-33 release by airway epithelium
    • Uchida M, Anderson EL, Squillace DL, et al. Oxidative stress serves as a key checkpoint for IL-33 release by airway epithelium. Allergy. 2017;72:1521-1531.
    • (2017) Allergy , vol.72 , pp. 1521-1531
    • Uchida, M.1    Anderson, E.L.2    Squillace, D.L.3
  • 73
    • 84953284110 scopus 로고    scopus 로고
    • Group 2 innate lymphoid cells utilize the IRF4-IL-9 module to coordinate epithelial cell maintenance of lung homeostasis
    • Mohapatra A, Van Dyken SJ, Schneider C, Nussbaum JC, Liang HE, Locksley RM. Group 2 innate lymphoid cells utilize the IRF4-IL-9 module to coordinate epithelial cell maintenance of lung homeostasis. Mucosal Immunol. 2015;9:275-286.
    • (2015) Mucosal Immunol , vol.9 , pp. 275-286
    • Mohapatra, A.1    Van Dyken, S.J.2    Schneider, C.3    Nussbaum, J.C.4    Liang, H.E.5    Locksley, R.M.6
  • 74
    • 53149119525 scopus 로고    scopus 로고
    • Nuclear interleukin-33 is generally expressed in resting endothelium but rapidly lost upon angiogenic or proinflammatory activation
    • Kuchler AM, Pollheimer J, Balogh J, et al. Nuclear interleukin-33 is generally expressed in resting endothelium but rapidly lost upon angiogenic or proinflammatory activation. Am J Pathol. 2008;173:1229-1242.
    • (2008) Am J Pathol , vol.173 , pp. 1229-1242
    • Kuchler, A.M.1    Pollheimer, J.2    Balogh, J.3
  • 75
    • 84865221699 scopus 로고    scopus 로고
    • The alarmin IL-33 is a notch target in quiescent endothelial cells
    • Sundlisaeter E, Edelmann RJ, Hol J, et al. The alarmin IL-33 is a notch target in quiescent endothelial cells. Am J Pathol. 2012;181:1099-1111.
    • (2012) Am J Pathol , vol.181 , pp. 1099-1111
    • Sundlisaeter, E.1    Edelmann, R.J.2    Hol, J.3
  • 76
    • 79960721309 scopus 로고    scopus 로고
    • NKT cells are required to induce high IL-33 expression in hepatocytes during ConA-induced acute hepatitis
    • Arshad MI, Rauch M, L'Helgoualc'h A, et al. NKT cells are required to induce high IL-33 expression in hepatocytes during ConA-induced acute hepatitis. Eur J Immunol. 2011;41:2341-2348.
    • (2011) Eur J Immunol , vol.41 , pp. 2341-2348
    • Arshad, M.I.1    Rauch, M.2    L'Helgoualc'h, A.3
  • 77
    • 84903594513 scopus 로고    scopus 로고
    • Unique temporal and spatial expression patterns of IL-33 in ovaries during ovulation and estrous cycle are associated with ovarian tissue homeostasis
    • Carlock CI, Wu J, Zhou C, et al. Unique temporal and spatial expression patterns of IL-33 in ovaries during ovulation and estrous cycle are associated with ovarian tissue homeostasis. J Immunol. 2014;193:161-169.
    • (2014) J Immunol , vol.193 , pp. 161-169
    • Carlock, C.I.1    Wu, J.2    Zhou, C.3
  • 78
    • 84887459057 scopus 로고    scopus 로고
    • Neutralisation of the interleukin-33/ST2 pathway ameliorates experimental colitis through enhancement of mucosal healing in mice
    • Sedhom MA, Pichery M, Murdoch JR, et al. Neutralisation of the interleukin-33/ST2 pathway ameliorates experimental colitis through enhancement of mucosal healing in mice. Gut. 2013;62:1714-1723.
    • (2013) Gut , vol.62 , pp. 1714-1723
    • Sedhom, M.A.1    Pichery, M.2    Murdoch, J.R.3
  • 79
    • 84871662121 scopus 로고    scopus 로고
    • Disordered IL-33/ST2 activation in decidualizing stromal cells prolongs uterine receptivity in women with recurrent pregnancy loss
    • Salker MS, Nautiyal J, Steel JH, et al. Disordered IL-33/ST2 activation in decidualizing stromal cells prolongs uterine receptivity in women with recurrent pregnancy loss. PLoS ONE. 2012;7:e52252.
    • (2012) PLoS ONE , vol.7
    • Salker, M.S.1    Nautiyal, J.2    Steel, J.H.3
  • 80
    • 84931568385 scopus 로고    scopus 로고
    • Epidermal expression and regulation of interleukin-33 during homeostasis and inflammation: Strong species differences
    • Sundnes O, Pietka W, Loos T, et al. Epidermal expression and regulation of interleukin-33 during homeostasis and inflammation: Strong species differences. J Invest Dermatol. 2015;135:1771-1780.
    • (2015) J Invest Dermatol , vol.135 , pp. 1771-1780
    • Sundnes, O.1    Pietka, W.2    Loos, T.3
  • 81
    • 84886431989 scopus 로고    scopus 로고
    • IL-33, but not IL-25, is crucial for the development of house dust mite antigen-induced allergic rhinitis
    • Nakanishi W, Yamaguchi S, Matsuda A, et al. IL-33, but not IL-25, is crucial for the development of house dust mite antigen-induced allergic rhinitis. PLoS ONE. 2013;8:e78099.
    • (2013) PLoS ONE , vol.8
    • Nakanishi, W.1    Yamaguchi, S.2    Matsuda, A.3
  • 82
    • 77649271174 scopus 로고    scopus 로고
    • Increased IL-33 expression by epithelial cells in bronchial asthma
    • Prefontaine D, Nadigel J, Chouiali F, et al. Increased IL-33 expression by epithelial cells in bronchial asthma. J Allergy Clin Immunol. 2010;125:752-754.
    • (2010) J Allergy Clin Immunol , vol.125 , pp. 752-754
    • Prefontaine, D.1    Nadigel, J.2    Chouiali, F.3
  • 83
    • 75549084963 scopus 로고    scopus 로고
    • Increased expression of IL-33 in severe asthma: Evidence of expression by airway smooth muscle cells
    • Prefontaine D, Lajoie-Kadoch S, Foley S, et al. Increased expression of IL-33 in severe asthma: Evidence of expression by airway smooth muscle cells. J Immunol. 2009;183:5094-5103.
    • (2009) J Immunol , vol.183 , pp. 5094-5103
    • Prefontaine, D.1    Lajoie-Kadoch, S.2    Foley, S.3
  • 84
    • 84883537459 scopus 로고    scopus 로고
    • Long-term IL-33-producing epithelial progenitor cells in chronic obstructive lung disease
    • Byers DE, Alexander-Brett J, Patel AC, et al. Long-term IL-33-producing epithelial progenitor cells in chronic obstructive lung disease. J Clin Invest. 2013;123:3967-3982.
    • (2013) J Clin Invest , vol.123 , pp. 3967-3982
    • Byers, D.E.1    Alexander-Brett, J.2    Patel, A.C.3
  • 85
    • 84873747719 scopus 로고    scopus 로고
    • IL-33 citrine reporter mice reveal the temporal and spatial expression of IL-33 during allergic lung inflammation
    • Hardman CS, Panova V, McKenzie AN. IL-33 citrine reporter mice reveal the temporal and spatial expression of IL-33 during allergic lung inflammation. Eur J Immunol. 2013;43:488-498.
    • (2013) Eur J Immunol , vol.43 , pp. 488-498
    • Hardman, C.S.1    Panova, V.2    McKenzie, A.N.3
  • 86
    • 84884905739 scopus 로고    scopus 로고
    • IL-33 is more potent than IL-25 in provoking IL-13-producing nuocytes (type 2 innate lymphoid cells) and airway contraction
    • Barlow JL, Peel S, Fox J, et al. IL-33 is more potent than IL-25 in provoking IL-13-producing nuocytes (type 2 innate lymphoid cells) and airway contraction. J Allergy Clin Immunol. 2013;132:933-941.
    • (2013) J Allergy Clin Immunol , vol.132 , pp. 933-941
    • Barlow, J.L.1    Peel, S.2    Fox, J.3
  • 87
    • 84964584567 scopus 로고    scopus 로고
    • The histone deacetylase inhibitor trichostatin A suppresses murine innate allergic inflammation by blocking group 2 innate lymphoid cell (ILC2) activation
    • Toki S, Goleniewska K, Reiss S, et al. The histone deacetylase inhibitor trichostatin A suppresses murine innate allergic inflammation by blocking group 2 innate lymphoid cell (ILC2) activation. Thorax. 2016;71:633-645.
    • (2016) Thorax , vol.71 , pp. 633-645
    • Toki, S.1    Goleniewska, K.2    Reiss, S.3
  • 88
    • 84862776994 scopus 로고    scopus 로고
    • IL-33 and ST2 in atopic dermatitis: Expression profiles and modulation by triggering factors
    • Savinko T, Matikainen S, Saarialho-Kere U, et al. IL-33 and ST2 in atopic dermatitis: Expression profiles and modulation by triggering factors. J Invest Dermatol. 2012;132:1392-1400.
    • (2012) J Invest Dermatol , vol.132 , pp. 1392-1400
    • Savinko, T.1    Matikainen, S.2    Saarialho-Kere, U.3
  • 89
    • 84954438899 scopus 로고    scopus 로고
    • DeltaNp63 regulates IL-33 and IL-31 signaling in atopic dermatitis
    • Rizzo JM, Oyelakin A, Min S, et al. DeltaNp63 regulates IL-33 and IL-31 signaling in atopic dermatitis. Cell Death Differ. 2016;23:1073-1085.
    • (2016) Cell Death Differ , vol.23 , pp. 1073-1085
    • Rizzo, J.M.1    Oyelakin, A.2    Min, S.3
  • 90
    • 84867859899 scopus 로고    scopus 로고
    • Regulation of IL-33 expression by IFN-gamma and tumor necrosis factor-alpha in normal human epidermal keratinocytes
    • Meephansan J, Tsuda H, Komine M, Tominaga S, Ohtsuki M. Regulation of IL-33 expression by IFN-gamma and tumor necrosis factor-alpha in normal human epidermal keratinocytes. J Invest Dermatol. 2012;132:2593-2600.
    • (2012) J Invest Dermatol , vol.132 , pp. 2593-2600
    • Meephansan, J.1    Tsuda, H.2    Komine, M.3    Tominaga, S.4    Ohtsuki, M.5
  • 91
    • 77952324145 scopus 로고    scopus 로고
    • Epithelial-derived IL-33 and its receptor ST2 are dysregulated in ulcerative colitis and in experimental Th1/Th2 driven enteritis
    • Pastorelli L, Garg RR, Hoang SB, et al. Epithelial-derived IL-33 and its receptor ST2 are dysregulated in ulcerative colitis and in experimental Th1/Th2 driven enteritis. Proc Natl Acad Sci USA. 2010;107:8017-8022.
    • (2010) Proc Natl Acad Sci USA , vol.107 , pp. 8017-8022
    • Pastorelli, L.1    Garg, R.R.2    Hoang, S.B.3
  • 92
    • 77955142252 scopus 로고    scopus 로고
    • Interleukin-33 overexpression is associated with liver fibrosis in mice and humans
    • Marvie P, Lisbonne M, L'Helgoualc'h A, et al. Interleukin-33 overexpression is associated with liver fibrosis in mice and humans. J Cell Mol Med. 2009;14:1726-1739.
    • (2009) J Cell Mol Med , vol.14 , pp. 1726-1739
    • Marvie, P.1    Lisbonne, M.2    L'Helgoualc'h, A.3
  • 94
    • 77950789564 scopus 로고    scopus 로고
    • Expression of interleukin 1-like cytokine interleukin 33 and its receptor complex (ST2L and IL1RAcP) in human pancreatic myofibroblasts
    • Nishida A, Andoh A, Imaeda H, Inatomi O, Shiomi H, Fujiyama Y. Expression of interleukin 1-like cytokine interleukin 33 and its receptor complex (ST2L and IL1RAcP) in human pancreatic myofibroblasts. Gut. 2010;59:531-541.
    • (2010) Gut , vol.59 , pp. 531-541
    • Nishida, A.1    Andoh, A.2    Imaeda, H.3    Inatomi, O.4    Shiomi, H.5    Fujiyama, Y.6
  • 95
    • 77949480323 scopus 로고    scopus 로고
    • The IL1-like cytokine IL33 and its receptor ST2 are abnormally expressed in the affected skin and visceral organs of patients with systemic sclerosis
    • Manetti M, Ibba-Manneschi L, Liakouli V, et al. The IL1-like cytokine IL33 and its receptor ST2 are abnormally expressed in the affected skin and visceral organs of patients with systemic sclerosis. Ann Rheum Dis. 2010;69:598-605.
    • (2010) Ann Rheum Dis , vol.69 , pp. 598-605
    • Manetti, M.1    Ibba-Manneschi, L.2    Liakouli, V.3
  • 96
    • 84964334535 scopus 로고    scopus 로고
    • Upregulation of interleukin-33 in obstructive renal injury
    • Chen WY, Chang YJ, Su CH, et al. Upregulation of interleukin-33 in obstructive renal injury. Biochem Biophys Res Commun. 2016;473:1026-1032.
    • (2016) Biochem Biophys Res Commun , vol.473 , pp. 1026-1032
    • Chen, W.Y.1    Chang, Y.J.2    Su, C.H.3
  • 97
    • 78650199530 scopus 로고    scopus 로고
    • Inflammatory bowel disease-associated interleukin-33 is preferentially expressed in ulceration-associated myofibroblasts
    • Sponheim J, Pollheimer J, Olsen T, et al. Inflammatory bowel disease-associated interleukin-33 is preferentially expressed in ulceration-associated myofibroblasts. Am J Path. 2010;177:2804-2815.
    • (2010) Am J Path , vol.177 , pp. 2804-2815
    • Sponheim, J.1    Pollheimer, J.2    Olsen, T.3
  • 98
    • 61649117392 scopus 로고    scopus 로고
    • Inhibition of interleukin-33 signaling attenuates the severity of experimental arthritis
    • Palmer G, Talabot-Ayer D, Lamacchia C, et al. Inhibition of interleukin-33 signaling attenuates the severity of experimental arthritis. Arthritis Rheum. 2009;60:738-749.
    • (2009) Arthritis Rheum , vol.60 , pp. 738-749
    • Palmer, G.1    Talabot-Ayer, D.2    Lamacchia, C.3
  • 99
    • 84927145585 scopus 로고    scopus 로고
    • MicroRNA29a regulates IL-33-mediated tissue remodelling in tendon disease
    • Millar NL, Gilchrist DS, Akbar M, et al. MicroRNA29a regulates IL-33-mediated tissue remodelling in tendon disease. Nat Commun. 2015;6:6774.
    • (2015) Nat Commun , vol.6 , pp. 6774
    • Millar, N.L.1    Gilchrist, D.S.2    Akbar, M.3
  • 100
    • 80052496061 scopus 로고    scopus 로고
    • The immune-modulating cytokine and endogenous Alarmin interleukin-33 is upregulated in skin exposed to inflammatory UVB radiation
    • Byrne SN, Beaugie C, O'Sullivan C, Leighton S, Halliday GM. The immune-modulating cytokine and endogenous Alarmin interleukin-33 is upregulated in skin exposed to inflammatory UVB radiation. Am J Pathol. 2011;179:211-222.
    • (2011) Am J Pathol , vol.179 , pp. 211-222
    • Byrne, S.N.1    Beaugie, C.2    O'Sullivan, C.3    Leighton, S.4    Halliday, G.M.5
  • 101
    • 84984863528 scopus 로고    scopus 로고
    • Fat-associated lymphoid clusters control local IgM secretion during pleural infection and lung inflammation
    • Jackson-Jones LH, Duncan SM, Magalhaes MS, et al. Fat-associated lymphoid clusters control local IgM secretion during pleural infection and lung inflammation. Nat Commun. 2016;7:12651.
    • (2016) Nat Commun , vol.7 , pp. 12651
    • Jackson-Jones, L.H.1    Duncan, S.M.2    Magalhaes, M.S.3
  • 102
    • 78249249625 scopus 로고    scopus 로고
    • Interleukin-33 expression is specifically enhanced in inflamed mucosa of ulcerative colitis
    • Kobori A, Yagi Y, Imaeda H, et al. Interleukin-33 expression is specifically enhanced in inflamed mucosa of ulcerative colitis. J Gastroenterology. 2010;45:999-1007.
    • (2010) J Gastroenterology , vol.45 , pp. 999-1007
    • Kobori, A.1    Yagi, Y.2    Imaeda, H.3
  • 104
    • 79953176269 scopus 로고    scopus 로고
    • Production and functions of IL-33 in the central nervous system
    • Yasuoka S, Kawanokuchi J, Parajuli B, et al. Production and functions of IL-33 in the central nervous system. Brain Res. 2011;1385:8-17.
    • (2011) Brain Res , vol.1385 , pp. 8-17
    • Yasuoka, S.1    Kawanokuchi, J.2    Parajuli, B.3
  • 105
    • 77954023823 scopus 로고    scopus 로고
    • Contribution of IL-33 to induction and augmentation of experimental allergic conjunctivitis
    • Matsuba-Kitamura S, Yoshimoto T, Yasuda K, et al. Contribution of IL-33 to induction and augmentation of experimental allergic conjunctivitis. Int Immunol. 2010;22:479-489.
    • (2010) Int Immunol , vol.22 , pp. 479-489
    • Matsuba-Kitamura, S.1    Yoshimoto, T.2    Yasuda, K.3
  • 106
    • 84870512750 scopus 로고    scopus 로고
    • TRAIL but not FasL and TNFalpha, regulates IL-33 expression in murine hepatocytes during acute hepatitis
    • Arshad MI, Piquet-Pellorce C, L'Helgoualc'h A, et al. TRAIL but not FasL and TNFalpha, regulates IL-33 expression in murine hepatocytes during acute hepatitis. Hepatology. 2012;56:2353-2362.
    • (2012) Hepatology , vol.56 , pp. 2353-2362
    • Arshad, M.I.1    Piquet-Pellorce, C.2    L'Helgoualc'h, A.3
  • 107
    • 79959380307 scopus 로고    scopus 로고
    • Innate lymphoid cells mediate influenza-induced airway hyper-reactivity independently of adaptive immunity
    • Chang YJ, Kim HY, Albacker LA, et al. Innate lymphoid cells mediate influenza-induced airway hyper-reactivity independently of adaptive immunity. Nat Immunol. 2011;12:631-638.
    • (2011) Nat Immunol , vol.12 , pp. 631-638
    • Chang, Y.J.1    Kim, H.Y.2    Albacker, L.A.3
  • 108
    • 84455169459 scopus 로고    scopus 로고
    • Innate lymphoid cells responding to IL-33 mediate airway hyperreactivity independently of adaptive immunity
    • Kim HY, Chang YJ, Subramanian S, et al. Innate lymphoid cells responding to IL-33 mediate airway hyperreactivity independently of adaptive immunity. J Allergy Clin Immunol. 2012;129(216–27):e6.
    • (2012) J Allergy Clin Immunol , vol.129 , Issue.216-27
    • Kim, H.Y.1    Chang, Y.J.2    Subramanian, S.3
  • 109
    • 84860357324 scopus 로고    scopus 로고
    • Trefoil factor 2 rapidly induces interleukin 33 to promote type 2 immunity during allergic asthma and hookworm infection
    • Wills-Karp M, Rani R, Dienger K, et al. Trefoil factor 2 rapidly induces interleukin 33 to promote type 2 immunity during allergic asthma and hookworm infection. J Exp Med. 2012;209:607-622.
    • (2012) J Exp Med , vol.209 , pp. 607-622
    • Wills-Karp, M.1    Rani, R.2    Dienger, K.3
  • 110
    • 84885130812 scopus 로고    scopus 로고
    • Macrophage-derived IL-33 is a critical factor for placental growth
    • Fock V, Mairhofer M, Otti GR, et al. Macrophage-derived IL-33 is a critical factor for placental growth. J Immunol. 2013;191:3734-3743.
    • (2013) J Immunol , vol.191 , pp. 3734-3743
    • Fock, V.1    Mairhofer, M.2    Otti, G.R.3
  • 111
    • 77957787918 scopus 로고    scopus 로고
    • IL-33 is produced by mast cells and regulates IgE-dependent inflammation
    • Hsu CL, Neilsen CV, Bryce PJ. IL-33 is produced by mast cells and regulates IgE-dependent inflammation. PLoS ONE. 2010;5:e11944.
    • (2010) PLoS ONE , vol.5
    • Hsu, C.L.1    Neilsen, C.V.2    Bryce, P.J.3
  • 113
    • 85019408499 scopus 로고    scopus 로고
    • Mast cells are crucial for induction of group 2 innate lymphoid cells and clearance of Helminth infections
    • Shimokawa C, Kanaya T, Hachisuka M, et al. Mast cells are crucial for induction of group 2 innate lymphoid cells and clearance of Helminth infections. Immunity. 2017;46(863–74):e4.
    • (2017) Immunity , vol.46 , Issue.863-74
    • Shimokawa, C.1    Kanaya, T.2    Hachisuka, M.3
  • 114
    • 76249084409 scopus 로고    scopus 로고
    • Caspase-1, caspase-8, and calpain are dispensable for IL-33 release by macrophages
    • Ohno T, Oboki K, Kajiwara N, et al. Caspase-1, caspase-8, and calpain are dispensable for IL-33 release by macrophages. Journal of Immunology. 2009;183:7890-7897.
    • (2009) Journal of Immunology , vol.183 , pp. 7890-7897
    • Ohno, T.1    Oboki, K.2    Kajiwara, N.3
  • 115
    • 84877144764 scopus 로고    scopus 로고
    • IL-33-dependent induction of allergic lung inflammation by FcgammaRIII signaling
    • Tjota MY, Williams JW, Lu T, et al. IL-33-dependent induction of allergic lung inflammation by FcgammaRIII signaling. J Clin Invest. 2013;123:2287-2297.
    • (2013) J Clin Invest , vol.123 , pp. 2287-2297
    • Tjota, M.Y.1    Williams, J.W.2    Lu, T.3
  • 116
    • 84936761972 scopus 로고    scopus 로고
    • IL-33 signaling contributes to the pathogenesis of myeloproliferative neoplasms
    • Mager LF, Riether C, Schurch CM, et al. IL-33 signaling contributes to the pathogenesis of myeloproliferative neoplasms. J Clin Invest. 2015;125:2579-2591.
    • (2015) J Clin Invest , vol.125 , pp. 2579-2591
    • Mager, L.F.1    Riether, C.2    Schurch, C.M.3
  • 117
    • 84919339989 scopus 로고    scopus 로고
    • IL-33-dependent type 2 inflammation during rhinovirus-induced asthma exacerbations in vivo
    • Jackson DJ, Makrinioti H, Rana BM, et al. IL-33-dependent type 2 inflammation during rhinovirus-induced asthma exacerbations in vivo. Am J Respir Crit Care Med. 2014;190:1373-1382.
    • (2014) Am J Respir Crit Care Med , vol.190 , pp. 1373-1382
    • Jackson, D.J.1    Makrinioti, H.2    Rana, B.M.3
  • 118
    • 85012254755 scopus 로고    scopus 로고
    • Characterization of meningeal type 2 innate lymphocytes and their response to CNS injury
    • Gadani SP, Smirnov I, Smith AT, Overall CC, Kipnis J. Characterization of meningeal type 2 innate lymphocytes and their response to CNS injury. J Exp Med. 2017;214:285-296.
    • (2017) J Exp Med , vol.214 , pp. 285-296
    • Gadani, S.P.1    Smirnov, I.2    Smith, A.T.3    Overall, C.C.4    Kipnis, J.5
  • 119
    • 84977667833 scopus 로고    scopus 로고
    • IL-33 promotes food anaphylaxis in epicutaneously sensitized mice by targeting mast cells
    • Galand C, Leyva-Castillo JM, Yoon J, et al. IL-33 promotes food anaphylaxis in epicutaneously sensitized mice by targeting mast cells. J Allergy Clin Immunol. 2016;138:1356-1366.
    • (2016) J Allergy Clin Immunol , vol.138 , pp. 1356-1366
    • Galand, C.1    Leyva-Castillo, J.M.2    Yoon, J.3
  • 120
    • 84897107723 scopus 로고    scopus 로고
    • Immediate-type contact hypersensitivity is reduced in interleukin-33 knockout mice
    • Imai Y, Yasuda K, Sakaguchi Y, et al. Immediate-type contact hypersensitivity is reduced in interleukin-33 knockout mice. J Dermatol Sci. 2014;74:159-161.
    • (2014) J Dermatol Sci , vol.74 , pp. 159-161
    • Imai, Y.1    Yasuda, K.2    Sakaguchi, Y.3
  • 121
    • 34249882513 scopus 로고    scopus 로고
    • IL-33 and ST2 comprise a critical biomechanically induced and cardioprotective signaling system
    • Sanada S, Hakuno D, Higgins LJ, Schreiter ER, McKenzie AN, Lee RT. IL-33 and ST2 comprise a critical biomechanically induced and cardioprotective signaling system. J Clin Invest. 2007;117:1538-1549.
    • (2007) J Clin Invest , vol.117 , pp. 1538-1549
    • Sanada, S.1    Hakuno, D.2    Higgins, L.J.3    Schreiter, E.R.4    McKenzie, A.N.5    Lee, R.T.6
  • 122
    • 84887509940 scopus 로고    scopus 로고
    • Bee venom phospholipase A2 induces a primary type 2 response that is dependent on the receptor ST2 and confers protective immunity
    • Palm NW, Rosenstein RK, Yu S, Schenten DD, Florsheim E, Medzhitov R. Bee venom phospholipase A2 induces a primary type 2 response that is dependent on the receptor ST2 and confers protective immunity. Immunity. 2013;39:976-985.
    • (2013) Immunity , vol.39 , pp. 976-985
    • Palm, N.W.1    Rosenstein, R.K.2    Yu, S.3    Schenten, D.D.4    Florsheim, E.5    Medzhitov, R.6
  • 123
    • 84939499267 scopus 로고    scopus 로고
    • IL-33 released by alum is responsible for early cytokine production and has adjuvant properties
    • Rose WA 2nd, Okragly AJ, Patel CN, Benschop RJ. IL-33 released by alum is responsible for early cytokine production and has adjuvant properties. Sci Rep. 2015;5:13146.
    • (2015) Sci Rep , vol.5 , pp. 13146
    • Rose, W.A.1    Okragly, A.J.2    Patel, C.N.3    Benschop, R.J.4
  • 124
    • 84901422731 scopus 로고    scopus 로고
    • RIPK1 regulates RIPK3-MLKL-driven systemic inflammation and emergency hematopoiesis
    • Rickard JA, O'Donnell JA, Evans JM, et al. RIPK1 regulates RIPK3-MLKL-driven systemic inflammation and emergency hematopoiesis. Cell. 2014;157:1175-1188.
    • (2014) Cell , vol.157 , pp. 1175-1188
    • Rickard, J.A.1    O'Donnell, J.A.2    Evans, J.M.3
  • 125
    • 79955040263 scopus 로고    scopus 로고
    • The danger signal, extracellular ATP, is a sensor for an airborne allergen and triggers IL-33 release and innate Th2-type responses
    • Kouzaki H, Iijima K, Kobayashi T, O'Grady SM, Kita H. The danger signal, extracellular ATP, is a sensor for an airborne allergen and triggers IL-33 release and innate Th2-type responses. J Immunol. 2011;186:4375-4387.
    • (2011) J Immunol , vol.186 , pp. 4375-4387
    • Kouzaki, H.1    Iijima, K.2    Kobayashi, T.3    O'Grady, S.M.4    Kita, H.5
  • 126
    • 84948845194 scopus 로고    scopus 로고
    • Airway epithelial dual oxidase 1 mediates allergen-induced IL-33 secretion and activation of type 2 immune responses
    • Hristova M, Habibovic A, Veith C, et al. Airway epithelial dual oxidase 1 mediates allergen-induced IL-33 secretion and activation of type 2 immune responses. J Allergy Clin Immunol. 2016;137(1545–56):e11.
    • (2016) J Allergy Clin Immunol , vol.137 , Issue.1545-56
    • Hristova, M.1    Habibovic, A.2    Veith, C.3
  • 127
    • 84905968184 scopus 로고    scopus 로고
    • Alternaria-derived serine protease activity drives IL-33 mediated asthma exacerbations
    • Snelgrove RJ, Gregory LG, Peiro T, et al. Alternaria-derived serine protease activity drives IL-33 mediated asthma exacerbations. J Allergy Clin Immunol. 2014;134:583-592.
    • (2014) J Allergy Clin Immunol , vol.134 , pp. 583-592
    • Snelgrove, R.J.1    Gregory, L.G.2    Peiro, T.3
  • 128
    • 84904241397 scopus 로고    scopus 로고
    • Blockade of IL-33 release and suppression of type 2 innate lymphoid cell responses by helminth secreted products in airway allergy
    • McSorley HJ, Blair NF, Smith KA, McKenzie AN, Maizels RM. Blockade of IL-33 release and suppression of type 2 innate lymphoid cell responses by helminth secreted products in airway allergy. Mucosal Immunol. 2014;7:1068-1078.
    • (2014) Mucosal Immunol , vol.7 , pp. 1068-1078
    • McSorley, H.J.1    Blair, N.F.2    Smith, K.A.3    McKenzie, A.N.4    Maizels, R.M.5
  • 129
    • 84856728530 scopus 로고    scopus 로고
    • Alternaria-induced release of IL-18 from damaged airway epithelial cells: An NF-kappaB dependent mechanism of Th2 differentiation?
    • Murai H, Qi H, Choudhury B, et al. Alternaria-induced release of IL-18 from damaged airway epithelial cells: An NF-kappaB dependent mechanism of Th2 differentiation? PLoS ONE. 2012;7:e30280.
    • (2012) PLoS ONE , vol.7
    • Murai, H.1    Qi, H.2    Choudhury, B.3
  • 130
    • 84876782951 scopus 로고    scopus 로고
    • IL-33-mediated innate response and adaptive immune cells contribute to maximum responses of protease allergen-induced allergic airway inflammation
    • Kamijo S, Takeda H, Tokura T, et al. IL-33-mediated innate response and adaptive immune cells contribute to maximum responses of protease allergen-induced allergic airway inflammation. J Immunol. 2013;190:4489-4499.
    • (2013) J Immunol , vol.190 , pp. 4489-4499
    • Kamijo, S.1    Takeda, H.2    Tokura, T.3
  • 131
    • 84899517328 scopus 로고    scopus 로고
    • Airway uric acid is a sensor of inhaled protease allergens and initiates type 2 immune responses in respiratory mucosa
    • Hara K, Iijima K, Elias MK, et al. Airway uric acid is a sensor of inhaled protease allergens and initiates type 2 immune responses in respiratory mucosa. J Immunol. 2014;192:4032-4042.
    • (2014) J Immunol , vol.192 , pp. 4032-4042
    • Hara, K.1    Iijima, K.2    Elias, M.K.3
  • 132
    • 23644456321 scopus 로고    scopus 로고
    • ROS generated by pollen NADPH oxidase provide a signal that augments antigen-induced allergic airway inflammation
    • Boldogh I, Bacsi A, Choudhury BK, et al. ROS generated by pollen NADPH oxidase provide a signal that augments antigen-induced allergic airway inflammation. J Clin Invest. 2005;115:2169-2179.
    • (2005) J Clin Invest , vol.115 , pp. 2169-2179
    • Boldogh, I.1    Bacsi, A.2    Choudhury, B.K.3
  • 133
    • 84893646178 scopus 로고    scopus 로고
    • IL-33 is a mediator rather than a trigger of the acute allergic response in humans
    • Fux M, Pecaric-Petkovic T, Odermatt A, et al. IL-33 is a mediator rather than a trigger of the acute allergic response in humans. Allergy. 2014;69:216-222.
    • (2014) Allergy , vol.69 , pp. 216-222
    • Fux, M.1    Pecaric-Petkovic, T.2    Odermatt, A.3
  • 134
    • 79960924748 scopus 로고    scopus 로고
    • TLR-mediated induction of pro-allergic cytokine IL-33 in ocular mucosal epithelium
    • Zhang L, Lu R, Zhao G, Pflugfelder SC, Li DQ. TLR-mediated induction of pro-allergic cytokine IL-33 in ocular mucosal epithelium. Int J Biochem Cell Biol. 2011;43:1383-1391.
    • (2011) Int J Biochem Cell Biol , vol.43 , pp. 1383-1391
    • Zhang, L.1    Lu, R.2    Zhao, G.3    Pflugfelder, S.C.4    Li, D.Q.5
  • 135
    • 85021755870 scopus 로고    scopus 로고
    • Full length interleukin 33 aggravates radiation-induced skin reaction
    • Kurow O, Frey B, Schuster L, et al. Full length interleukin 33 aggravates radiation-induced skin reaction. Front Immunol. 2017;8:722.
    • (2017) Front Immunol , vol.8 , pp. 722
    • Kurow, O.1    Frey, B.2    Schuster, L.3
  • 136
    • 73949088791 scopus 로고    scopus 로고
    • Caspase 3 inactivates biologically active full length interleukin-33 as a classical cytokine but does not prohibit nuclear translocation
    • Ali S, Nguyen DQ, Falk W, Martin MU. Caspase 3 inactivates biologically active full length interleukin-33 as a classical cytokine but does not prohibit nuclear translocation. Biochem Biophys Res Commun. 2010;391:1512-1516.
    • (2010) Biochem Biophys Res Commun , vol.391 , pp. 1512-1516
    • Ali, S.1    Nguyen, D.Q.2    Falk, W.3    Martin, M.U.4
  • 137
    • 84930933217 scopus 로고    scopus 로고
    • AMCase is a crucial regulator of type 2 immune responses to inhaled house dust mites
    • Kim LK, Morita R, Kobayashi Y, et al. AMCase is a crucial regulator of type 2 immune responses to inhaled house dust mites. Proc Natl Acad Sci USA. 2015;112:E2891-E2899.
    • (2015) Proc Natl Acad Sci USA , vol.112 , pp. E2891-E2899
    • Kim, L.K.1    Morita, R.2    Kobayashi, Y.3
  • 138
    • 58149287750 scopus 로고    scopus 로고
    • Targeted peptidecentric proteomics reveals caspase-7 as a substrate of the caspase-1 inflammasomes
    • Lamkanfi M, Kanneganti TD, Van Damme P, et al. Targeted peptidecentric proteomics reveals caspase-7 as a substrate of the caspase-1 inflammasomes. Mol Cell Proteomics. 2008;7:2350-2363.
    • (2008) Mol Cell Proteomics , vol.7 , pp. 2350-2363
    • Lamkanfi, M.1    Kanneganti, T.D.2    Van Damme, P.3
  • 139
    • 84860325913 scopus 로고    scopus 로고
    • Inflammasome-activated caspase 7 cleaves PARP1 to enhance the expression of a subset of NF-kappaB target genes
    • Erener S, Petrilli V, Kassner I, et al. Inflammasome-activated caspase 7 cleaves PARP1 to enhance the expression of a subset of NF-kappaB target genes. Mol Cell. 2012;46:200-211.
    • (2012) Mol Cell , vol.46 , pp. 200-211
    • Erener, S.1    Petrilli, V.2    Kassner, I.3
  • 140
    • 84939631887 scopus 로고    scopus 로고
    • Caspase-1 activation by NLRP3 inflammasome dampens IL-33-dependent house dust mite-induced allergic lung inflammation
    • Madouri F, Guillou N, Fauconnier L, et al. Caspase-1 activation by NLRP3 inflammasome dampens IL-33-dependent house dust mite-induced allergic lung inflammation. J Mol Cell Biol. 2015;7:351-365.
    • (2015) J Mol Cell Biol , vol.7 , pp. 351-365
    • Madouri, F.1    Guillou, N.2    Fauconnier, L.3
  • 142
    • 84883190168 scopus 로고    scopus 로고
    • Mast cell chymase modulates IL-33 levels and controls allergic sensitization in dust-mite induced airway inflammation
    • Waern I, Lundequist A, Pejler G, Wernersson S. Mast cell chymase modulates IL-33 levels and controls allergic sensitization in dust-mite induced airway inflammation. Mucosal Immunol. 2013;6:911-920.
    • (2013) Mucosal Immunol , vol.6 , pp. 911-920
    • Waern, I.1    Lundequist, A.2    Pejler, G.3    Wernersson, S.4
  • 143
    • 84863268229 scopus 로고    scopus 로고
    • Contradictory functions (activation/termination) of neutrophil proteinase 3 enzyme (PR3) in interleukin-33 biological activity
    • Bae S, Kang T, Hong J, et al. Contradictory functions (activation/termination) of neutrophil proteinase 3 enzyme (PR3) in interleukin-33 biological activity. J Biol Chem. 2012;287:8205-8213.
    • (2012) J Biol Chem , vol.287 , pp. 8205-8213
    • Bae, S.1    Kang, T.2    Hong, J.3
  • 144
    • 34548825396 scopus 로고    scopus 로고
    • Soluble ST2 blocks interleukin-33 signaling in allergic airway inflammation
    • Hayakawa H, Hayakawa M, Kume A, Tominaga S. Soluble ST2 blocks interleukin-33 signaling in allergic airway inflammation. J Biol Chem. 2007;282:26369-26380.
    • (2007) J Biol Chem , vol.282 , pp. 26369-26380
    • Hayakawa, H.1    Hayakawa, M.2    Kume, A.3    Tominaga, S.4
  • 145
    • 84951566841 scopus 로고    scopus 로고
    • Activated mast cells synthesize and release soluble ST2-a decoy receptor for IL-33
    • Bandara G, Beaven MA, Olivera A, Gilfillan AM, Metcalfe DD. Activated mast cells synthesize and release soluble ST2-a decoy receptor for IL-33. Eur J Immunol. 2015;45:3034-3044.
    • (2015) Eur J Immunol , vol.45 , pp. 3034-3044
    • Bandara, G.1    Beaven, M.A.2    Olivera, A.3    Gilfillan, A.M.4    Metcalfe, D.D.5
  • 146
    • 0036772860 scopus 로고    scopus 로고
    • Activated, but not resting human Th2 cells, in contrast to Th1 and T regulatory cells, produce soluble ST2 and express low levels of ST2L at the cell surface
    • Lecart S, Lecointe N, Subramaniam A, et al. Activated, but not resting human Th2 cells, in contrast to Th1 and T regulatory cells, produce soluble ST2 and express low levels of ST2L at the cell surface. Eur J Immunol. 2002;32:2979-2987.
    • (2002) Eur J Immunol , vol.32 , pp. 2979-2987
    • Lecart, S.1    Lecointe, N.2    Subramaniam, A.3
  • 147
    • 85020927932 scopus 로고    scopus 로고
    • The IL-33/ST2 axis is crucial in type 2 airway responses induced by Staphylococcus aureus-derived serine protease-like protein D
    • Teufelberger AR, Nordengrun M, Braun H, et al. The IL-33/ST2 axis is crucial in type 2 airway responses induced by Staphylococcus aureus-derived serine protease-like protein D. J Allergy Clin Immunol. 2017. https://doi.org/10.1016/j.jaci.2017.05.004.
    • (2017) J Allergy Clin Immunol
    • Teufelberger, A.R.1    Nordengrun, M.2    Braun, H.3
  • 148
    • 29244477844 scopus 로고    scopus 로고
    • A human protein atlas for normal and cancer tissues based on antibody proteomics
    • Uhlen M, Bjorling E, Agaton C, et al. A human protein atlas for normal and cancer tissues based on antibody proteomics. Mol Cell Proteomics. 2005;4:1920-1932.
    • (2005) Mol Cell Proteomics , vol.4 , pp. 1920-1932
    • Uhlen, M.1    Bjorling, E.2    Agaton, C.3
  • 149
    • 84920269464 scopus 로고    scopus 로고
    • Proteomics. Tissue-based map of the human proteome
    • Uhlen M, Fagerberg L, Hallstrom BM, et al. Proteomics. Tissue-based map of the human proteome. Science. 2015;347:1260419.
    • (2015) Science , vol.347 , pp. 1260419
    • Uhlen, M.1    Fagerberg, L.2    Hallstrom, B.M.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.