IL-33 amplifies an innate immune response in the degenerating retina

Journal of Experimental Medicine

Volumn 213, Issue 2, 2016, Pages 189-207

  Xi, Hongkang ^a   Katschke, Kenneth J ^a   Li, Yun ^a   Truong, Tom ^a   Lee, Wyne P ^a   Diehl, Lauri ^a   Rangell, Linda ^a   Tao, Jianhua ^a   Arceo, Rommel ^a   Eastham Anderson, Jeffrey ^a   Hackney, Jason A ^a   Iglesias, Antonio ^b   Cote Sierra, Javier ^b,c   Elstrott, Justin ^a   Weimer, Robby M ^a   Van Lookeren Campagne, Menno ^a  

^a GENENTECH INC   (United States)

^b F HOFFMANN LA ROCHE LTD   (Switzerland)

^c PFIZER INC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CARBON TETRACHLORIDE; INTERFERON REGULATORY FACTOR 1; INTERFERON REGULATORY FACTOR 7; INTERLEUKIN 1 RECEPTOR ACCESSORY PROTEIN; INTERLEUKIN 18; INTERLEUKIN 1ALPHA; INTERLEUKIN 1BETA; INTERLEUKIN 33; INTERLEUKIN 33 RECEPTOR ALPHA; INTERLEUKIN 6; INTERLEUKIN RECEPTOR; MONOCYTE CHEMOTACTIC PROTEIN 1; SOMATOSTATIN RECEPTOR 2; STAT3 PROTEIN; UNCLASSIFIED DRUG; CELL SURFACE RECEPTOR; CYTOKINE; IL1RL1 PROTEIN, HUMAN; IL1RL1 PROTEIN, MOUSE; IL33 PROTEIN, HUMAN; IL33 PROTEIN, MOUSE; IL33 PROTEIN, RAT; INTERLEUKIN 1 RECEPTOR LIKE 1 PROTEIN;

AGE RELATED MACULAR DEGENERATION; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL LOSS; COMPARATIVE STUDY; CONTROLLED STUDY; CYTOKINE PRODUCTION; CYTOKINE RELEASE; FEMALE; HUMAN; HUMAN CELL; IMMUNOPATHOGENESIS; INNATE IMMUNITY; MALE; MEDIATOR RELEASE; MONONUCLEAR PHAGOCYTE; MOUSE; MUELLER CELL; NONHUMAN; PHOTORECEPTOR; PHOTORECEPTOR CELL; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; RAT; REGULATORY MECHANISM; RETINA INJURY; RETINAL THICKNESS; AGED; ANIMAL; BAGG ALBINO MOUSE; C57BL MOUSE; CASE CONTROL STUDY; CELL NUCLEUS; CHEMISTRY; DEFICIENCY; GENETICS; IMMUNOLOGY; IN VITRO STUDY; KNOCKOUT MOUSE; MACROGLIA; MACULAR DEGENERATION; METABOLISM; PATHOLOGY; PROTEIN PROCESSING; RETINA MACULA LUTEA; RETINAL PIGMENT EPITHELIUM; VERY ELDERLY;

AGED; AGED, 80 AND OVER; ANIMALS; CASE-CONTROL STUDIES; CELL NUCLEUS; CYTOKINES; EPENDYMOGLIAL CELLS; FEMALE; HUMANS; IMMUNITY, INNATE; IN VITRO TECHNIQUES; INTERLEUKIN-1 RECEPTOR-LIKE 1 PROTEIN; INTERLEUKIN-33; MACULA LUTEA; MACULAR DEGENERATION; MALE; MICE; MICE, INBRED BALB C; MICE, INBRED C57BL; MICE, KNOCKOUT; PROTEIN PROCESSING, POST-TRANSLATIONAL; RATS; RECEPTORS, CELL SURFACE; RECEPTORS, INTERLEUKIN; RETINAL PIGMENT EPITHELIUM;

EID: 84961158652     PISSN: 00221007     EISSN: 15409538     Source Type: Journal    
DOI: 10.1084/jem.20150894     Document Type: Article

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