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Volumn 113, Issue 31, 2016, Pages 8765-8770

Alternative splicing of interleukin-33 and type 2 inflammation in asthma

Author keywords

[No Author keywords available]

Indexed keywords

INTERLEUKIN 33; STEM CELL FACTOR RECEPTOR; THYMIC STROMAL LYMPHOPOIETIN; TRANSCRIPTION FACTOR GATA 2; IL1RL1 PROTEIN, HUMAN; INTERLEUKIN 1 RECEPTOR LIKE 1 PROTEIN;

EID: 84982684032     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1601914113     Document Type: Article
Times cited : (125)

References (46)
  • 1
    • 69249150516 scopus 로고    scopus 로고
    • T-helper type 2-driven inflammation defines major subphenotypes of asthma
    • Woodruff PG, et al. (2009) T-helper type 2-driven inflammation defines major subphenotypes of asthma. Am J Respir Crit Care Med 180(5):388-395.
    • (2009) Am J Respir Crit Care Med , vol.180 , Issue.5 , pp. 388-395
    • Woodruff, P.G.1
  • 2
    • 55149113944 scopus 로고    scopus 로고
    • Welcome to the neighborhood: Epithelial cell-derived cytokines license innate and adaptive immune responses at mucosal sites
    • Saenz SA, Taylor BC, Artis D (2008)Welcome to the neighborhood: Epithelial cell-derived cytokines license innate and adaptive immune responses at mucosal sites. Immunol Rev 226:172-190.
    • (2008) Immunol Rev , vol.226 , pp. 172-190
    • Saenz, S.A.1    Taylor, B.C.2    Artis, D.3
  • 3
    • 0028871967 scopus 로고
    • ST2/T1 protein functionally binds to two secreted proteins from Balb/c 3T3 and human umbilical vein endothelial cells but does not bind interleukin 1
    • Kumar S, Minnich MD, Young PR (1995) ST2/T1 protein functionally binds to two secreted proteins from Balb/c 3T3 and human umbilical vein endothelial cells but does not bind interleukin 1. J Biol Chem 270(46):27905-27913.
    • (1995) J Biol Chem , vol.270 , Issue.46 , pp. 27905-27913
    • Kumar, S.1    Minnich, M.D.2    Young, P.R.3
  • 4
    • 0034689033 scopus 로고    scopus 로고
    • T1/ST2-deficient mice demonstrate the importance of T1/ST2 in developing primary T helper cell type 2 responses
    • Townsend MJ, Fallon PG, Matthews DJ, Jolin HE, McKenzie AN (2000) T1/ST2-deficient mice demonstrate the importance of T1/ST2 in developing primary T helper cell type 2 responses. J Exp Med 191(6):1069-1076.
    • (2000) J Exp Med , vol.191 , Issue.6 , pp. 1069-1076
    • Townsend, M.J.1    Fallon, P.G.2    Matthews, D.J.3    Jolin, H.E.4    McKenzie, A.N.5
  • 5
    • 0036408831 scopus 로고    scopus 로고
    • Expression and function of the ST2 gene in a murine model of allergic airway inflammation
    • Oshikawa K, Yanagisawa K, Tominaga S, Sugiyama Y (2002) Expression and function of the ST2 gene in a murine model of allergic airway inflammation. Clin Exp Allergy 32(10):1520-1526.
    • (2002) Clin Exp Allergy , vol.32 , Issue.10 , pp. 1520-1526
    • Oshikawa, K.1    Yanagisawa, K.2    Tominaga, S.3    Sugiyama, Y.4
  • 6
    • 44849117539 scopus 로고    scopus 로고
    • Administration of IL-33 induces airway hyperresponsiveness and goblet cell hyperplasia in the lungs in the absence of adaptive immune system
    • Kondo Y, et al. (2008) Administration of IL-33 induces airway hyperresponsiveness and goblet cell hyperplasia in the lungs in the absence of adaptive immune system. Int Immunol 20(6):791-800.
    • (2008) Int Immunol , vol.20 , Issue.6 , pp. 791-800
    • Kondo, Y.1
  • 7
    • 0032499678 scopus 로고    scopus 로고
    • T1/ST2 is preferentially expressed on murine Th2 cells, independent of interleukin 4, interleukin 5, and interleukin 10, and important for Th2 effector function
    • Löhning M, et al. (1998) T1/ST2 is preferentially expressed on murine Th2 cells, independent of interleukin 4, interleukin 5, and interleukin 10, and important for Th2 effector function. Proc Natl Acad Sci USA 95(12):6930-6935.
    • (1998) Proc Natl Acad Sci USA , vol.95 , Issue.12 , pp. 6930-6935
    • Löhning, M.1
  • 8
    • 37249049230 scopus 로고    scopus 로고
    • IL-33 induces IL-13 production by mouse mast cells independently of IgE-FcepsilonRI signals
    • Ho LH, et al. (2007) IL-33 induces IL-13 production by mouse mast cells independently of IgE-FcepsilonRI signals. J Leukoc Biol 82(6):1481-1490.
    • (2007) J Leukoc Biol , vol.82 , Issue.6 , pp. 1481-1490
    • Ho, L.H.1
  • 9
    • 48449089903 scopus 로고    scopus 로고
    • IL-33 amplifies both Th1-And Th2-Type responses through its activity on human basophils, allergen-reactive Th2 cells, iNKT and NK cells
    • Smithgall MD, et al. (2008) IL-33 amplifies both Th1-And Th2-Type responses through its activity on human basophils, allergen-reactive Th2 cells, iNKT and NK cells. Int Immunol 20(8):1019-1030.
    • (2008) Int Immunol , vol.20 , Issue.8 , pp. 1019-1030
    • Smithgall, M.D.1
  • 10
    • 84906822605 scopus 로고    scopus 로고
    • Enhanced innate type 2 immune response in peripheral blood from patients with asthma
    • Bartemes KR, Kephart GM, Fox SJ, Kita H (2014) Enhanced innate type 2 immune response in peripheral blood from patients with asthma. J Allergy Clin Immunol 134(3):671-678.e4.
    • (2014) J Allergy Clin Immunol , vol.134 , Issue.3 , pp. 671-678e4
    • Bartemes, K.R.1    Kephart, G.M.2    Fox, S.J.3    Kita, H.4
  • 11
    • 84937023688 scopus 로고    scopus 로고
    • IL-13 mediates IL-33-dependent mast cell and type 2 innate lymphoid cell effects on bronchial epithelial cells
    • Nagarkar DR, et al. (2015) IL-13 mediates IL-33-dependent mast cell and type 2 innate lymphoid cell effects on bronchial epithelial cells. J Allergy Clin Immunol 136(1): 202-205.
    • (2015) J Allergy Clin Immunol , vol.136 , Issue.1 , pp. 202-205
    • Nagarkar, D.R.1
  • 12
    • 27744446058 scopus 로고    scopus 로고
    • IL-33, an interleukin-1-like cytokine that signals via the IL-1 receptor-related protein ST2 and induces T helper type 2-Associated cytokines
    • Schmitz J, et al. (2005) IL-33, an interleukin-1-like cytokine that signals via the IL-1 receptor-related protein ST2 and induces T helper type 2-Associated cytokines. Immunity 23(5):479-490.
    • (2005) Immunity , vol.23 , Issue.5 , pp. 479-490
    • Schmitz, J.1
  • 13
    • 84896701857 scopus 로고    scopus 로고
    • Dissecting childhood asthma with nasal transcriptomics distinguishes subphenotypes of disease
    • Poole A, et al. (2014) Dissecting childhood asthma with nasal transcriptomics distinguishes subphenotypes of disease. J Allergy Clin Immunol 133(3):670-8.e12.
    • (2014) J Allergy Clin Immunol , vol.133 , Issue.3 , pp. 670-812
    • Poole, A.1
  • 14
    • 84858273561 scopus 로고    scopus 로고
    • Asthma clinical research network of the national heart, lung, and blood institute 2012 A large subgroup of mild-To-moderate asthma is persistently noneosinophilic
    • McGrath KW, et al.; Asthma Clinical Research Network of the National Heart, Lung, and Blood Institute (2012) A large subgroup of mild-To-moderate asthma is persistently noneosinophilic. Am J Respir Crit Care Med 185(6):612-619.
    • Am J Respir Crit Care Med , vol.185 , Issue.6 , pp. 612-619
    • McGrath, K.W.1
  • 15
    • 84863011729 scopus 로고    scopus 로고
    • IL-33-responsive lineage-CD25+ CD44(hi) lymphoid cells mediate innate type 2 immunity and allergic inflammation in the lungs
    • Bartemes KR, et al. (2012) IL-33-responsive lineage-CD25+ CD44(hi) lymphoid cells mediate innate type 2 immunity and allergic inflammation in the lungs. J Immunol 188(3):1503-1513.
    • (2012) J Immunol , vol.188 , Issue.3 , pp. 1503-1513
    • Bartemes, K.R.1
  • 16
    • 84896343916 scopus 로고    scopus 로고
    • Group 2 innate lymphoid cells are critical for the initiation of adaptive T helper 2 cell-mediated allergic lung inflammation
    • Halim TY, et al. (2014) Group 2 innate lymphoid cells are critical for the initiation of adaptive T helper 2 cell-mediated allergic lung inflammation. Immunity 40(3): 425-435.
    • (2014) Immunity , vol.40 , Issue.3 , pp. 425-435
    • Halim, T.Y.1
  • 17
    • 84896332584 scopus 로고    scopus 로고
    • Chitin activates parallel immune modules that direct distinct inflammatory responses via innate lymphoid type 2 and T cells
    • Van Dyken SJ, et al. (2014) Chitin activates parallel immune modules that direct distinct inflammatory responses via innate lymphoid type 2 and T cells. Immunity 40(3): 414-424.
    • (2014) Immunity , vol.40 , Issue.3 , pp. 414-424
    • Van Dyken, S.J.1
  • 18
    • 84901422731 scopus 로고    scopus 로고
    • RIPK1 regulates RIPK3-MLKL-driven systemic inflammation and emergency hematopoiesis
    • Rickard JA, et al. (2014) RIPK1 regulates RIPK3-MLKL-driven systemic inflammation and emergency hematopoiesis. Cell 157(5):1175-1188.
    • (2014) Cell , vol.157 , Issue.5 , pp. 1175-1188
    • Rickard, J.A.1
  • 19
    • 84919339989 scopus 로고    scopus 로고
    • IL-33-dependent type 2 inflammation during rhinovirus-induced asthma exacerbations in vivo
    • Jackson DJ, et al. (2014) IL-33-dependent type 2 inflammation during rhinovirus-induced asthma exacerbations in vivo. Am J Respir Crit CareMed 190(12):1373-1382.
    • (2014) Am J Respir Crit CareMed , vol.190 , Issue.12 , pp. 1373-1382
    • Jackson, D.J.1
  • 20
    • 84867893281 scopus 로고    scopus 로고
    • Novel splice variants of IL-33: Differential expression in normal and transformed cells
    • Tsuda H, et al. (2012) Novel splice variants of IL-33: differential expression in normal and transformed cells. J Invest Dermatol 132(11):2661-2664.
    • (2012) J Invest Dermatol , vol.132 , Issue.11 , pp. 2661-2664
    • Tsuda, H.1
  • 21
    • 84857484469 scopus 로고    scopus 로고
    • Interleukin 33 as a mechanically responsive cytokine secreted by living cells
    • Kakkar R, Hei H, Dobner S, Lee RT (2012) Interleukin 33 as a mechanically responsive cytokine secreted by living cells. J Biol Chem 287(9):6941-6948.
    • (2012) J Biol Chem , vol.287 , Issue.9 , pp. 6941-6948
    • Kakkar, R.1    Hei, H.2    Dobner, S.3    Lee, R.T.4
  • 22
    • 79955040263 scopus 로고    scopus 로고
    • The danger signal, extracellular ATP, is a sensor for an airborne allergen and triggers IL-33 release and innate Th2-Type responses
    • Kouzaki H, Iijima K, Kobayashi T, O'Grady SM, Kita H (2011) The danger signal, extracellular ATP, is a sensor for an airborne allergen and triggers IL-33 release and innate Th2-Type responses. J Immunol 186(7):4375-4387.
    • (2011) J Immunol , vol.186 , Issue.7 , pp. 4375-4387
    • Kouzaki, H.1    Iijima, K.2    Kobayashi, T.3    O'Grady, S.M.4    Kita, H.5
  • 23
    • 84883537459 scopus 로고    scopus 로고
    • Long-Term IL-33-producing epithelial progenitor cells in chronic obstructive lung disease
    • Byers DE, et al. (2013) Long-Term IL-33-producing epithelial progenitor cells in chronic obstructive lung disease. J Clin Invest 123(9):3967-3982.
    • (2013) J Clin Invest , vol.123 , Issue.9 , pp. 3967-3982
    • Byers, D.E.1
  • 24
    • 84905968184 scopus 로고    scopus 로고
    • Alternaria-derived serine protease activity drives IL-33-mediated asthma exacerbations
    • Snelgrove RJ, et al. (2014) Alternaria-derived serine protease activity drives IL-33-mediated asthma exacerbations. J Allergy Clin Immunol 134(3):583-592.e6.
    • (2014) J Allergy Clin Immunol , vol.134 , Issue.3 , pp. 583-592e6
    • Snelgrove, R.J.1
  • 25
    • 34848886843 scopus 로고    scopus 로고
    • Cutting edge: The ST2 ligand IL-33 potently activates and drives maturation of human mast cells
    • Allakhverdi Z, Smith DE, Comeau MR, Delespesse G (2007) Cutting edge: The ST2 ligand IL-33 potently activates and drives maturation of human mast cells. J Immunol 179(4): 2051-2054.
    • (2007) J Immunol , vol.179 , Issue.4 , pp. 2051-2054
    • Allakhverdi, Z.1    Smith, D.E.2    Comeau, M.R.3    Delespesse, G.4
  • 26
    • 84953639674 scopus 로고    scopus 로고
    • Increased numbers of activated group 2 innate lymphoid cells in the airways of patients with severe asthma and persistent airway eosinophilia
    • Smith SG, et al. (2016) Increased numbers of activated group 2 innate lymphoid cells in the airways of patients with severe asthma and persistent airway eosinophilia. J Allergy Clin Immunol 137(1):75-86.
    • (2016) J Allergy Clin Immunol , vol.137 , Issue.1 , pp. 75-86
    • Smith, S.G.1
  • 27
    • 84937022817 scopus 로고    scopus 로고
    • Persistence of asthma requires multiple feedback circuits involving type 2 innate lymphoid cells and IL-33
    • e14
    • Christianson CA, et al. (2015) Persistence of asthma requires multiple feedback circuits involving type 2 innate lymphoid cells and IL-33. J Allergy Clin Immunol 136(1):59-68. e14.
    • (2015) J Allergy Clin Immunol , vol.136 , Issue.1 , pp. 59-68
    • Christianson, C.A.1
  • 28
    • 35649028488 scopus 로고    scopus 로고
    • Genome-wide profiling identifies epithelial cell genes associated with asthma and with treatment response to corticosteroids
    • Woodruff PG, et al. (2007) Genome-wide profiling identifies epithelial cell genes associated with asthma and with treatment response to corticosteroids. Proc Natl Acad Sci USA 104(40):15858-15863.
    • (2007) Proc Natl Acad Sci USA , vol.104 , Issue.40 , pp. 15858-15863
    • Woodruff, P.G.1
  • 29
    • 84895064176 scopus 로고    scopus 로고
    • Measures of gene expression in sputum cells can identify TH2-high and TH2-low subtypes of asthma
    • Peters MC, et al. (2013) Measures of gene expression in sputum cells can identify TH2-high and TH2-low subtypes of asthma. J Allergy Clin Immunol 133(2):388-394.
    • (2013) J Allergy Clin Immunol , vol.133 , Issue.2 , pp. 388-394
    • Peters, M.C.1
  • 30
    • 81155158408 scopus 로고    scopus 로고
    • RNase H-dependent PCR (rhPCR): Improved specificity and single nucleotide polymorphism detection using blocked cleavable primers
    • Dobosy JR, et al. (2011) RNase H-dependent PCR (rhPCR): Improved specificity and single nucleotide polymorphism detection using blocked cleavable primers. BMC Biotechnol 11:80.
    • (2011) BMC Biotechnol , vol.11 , pp. 80
    • Dobosy, J.R.1
  • 31
    • 84883815093 scopus 로고    scopus 로고
    • Structural insights into the interaction of IL-33 with its receptors
    • Liu X, et al. (2013) Structural insights into the interaction of IL-33 with its receptors. Proc Natl Acad Sci USA 110(37):14918-14923.
    • (2013) Proc Natl Acad Sci USA , vol.110 , Issue.37 , pp. 14918-14923
    • Liu, X.1
  • 32
    • 85006167768 scopus 로고    scopus 로고
    • A qPCR-based metric of Th2 airway inflammation in asthma
    • Bhakta NR, et al. (2013) A qPCR-based metric of Th2 airway inflammation in asthma. Clin Transl Allergy 3(1):24.
    • (2013) Clin Transl Allergy , vol.3 , Issue.1 , pp. 24
    • Bhakta, N.R.1
  • 33
    • 84867773093 scopus 로고    scopus 로고
    • The transcription factor GATA3 is essential for the function of human type 2 innate lymphoid cells
    • Mjösberg J, et al. (2012) The transcription factor GATA3 is essential for the function of human type 2 innate lymphoid cells. Immunity 37(4):649-659.
    • (2012) Immunity , vol.37 , Issue.4 , pp. 649-659
    • Mjösberg, J.1
  • 34
    • 53249093714 scopus 로고    scopus 로고
    • Molecular mimicry between IL-33 and KSHV for attachment to chromatin through the H2A-H2B acidic pocket
    • Roussel L, Erard M, Cayrol C, Girard JP (2008) Molecular mimicry between IL-33 and KSHV for attachment to chromatin through the H2A-H2B acidic pocket. EMBO Rep 9(10):1006-1012.
    • (2008) EMBO Rep , vol.9 , Issue.10 , pp. 1006-1012
    • Roussel, L.1    Erard, M.2    Cayrol, C.3    Girard, J.P.4
  • 35
    • 80051926552 scopus 로고    scopus 로고
    • The dual function cytokine IL-33 interacts with the transcription factor NF-?B to dampen NF-?B-stimulated gene transcription
    • Ali S, et al. (2011) The dual function cytokine IL-33 interacts with the transcription factor NF-?B to dampen NF-?B-stimulated gene transcription. J Immunol 187(4): 1609-1616.
    • (2011) J Immunol , vol.187 , Issue.4 , pp. 1609-1616
    • Ali, S.1
  • 36
    • 33846101552 scopus 로고    scopus 로고
    • IL-33, the IL-1-like cytokine ligand for ST2 receptor, is a chromatin-Associated nuclear factor in vivo
    • Carriere V, et al. (2007) IL-33, the IL-1-like cytokine ligand for ST2 receptor, is a chromatin-Associated nuclear factor in vivo. Proc Natl Acad Sci USA 104(1):282-287.
    • (2007) Proc Natl Acad Sci USA , vol.104 , Issue.1 , pp. 282-287
    • Carriere, V.1
  • 37
    • 84922404569 scopus 로고    scopus 로고
    • Altered subcellular localization of IL-33 leads to non-resolving lethal inflammation
    • Bessa J, et al. (2014) Altered subcellular localization of IL-33 leads to non-resolving lethal inflammation. J Autoimmun 55:33-41.
    • (2014) J Autoimmun , vol.55 , pp. 33-41
    • Bessa, J.1
  • 38
    • 84941686678 scopus 로고    scopus 로고
    • Oxidation of the alarmin IL-33 regulates ST2-dependent inflammation
    • Cohen ES, et al. (2015) Oxidation of the alarmin IL-33 regulates ST2-dependent inflammation. Nat Commun 6:8327.
    • (2015) Nat Commun , vol.6 , pp. 8327
    • Cohen, E.S.1
  • 39
    • 84908541933 scopus 로고    scopus 로고
    • Central domain of IL-33 is cleaved by mast cell proteases for potent activation of group-2 innate lymphoid cells
    • Lefrançais E, et al. (2014) Central domain of IL-33 is cleaved by mast cell proteases for potent activation of group-2 innate lymphoid cells. Proc Natl Acad Sci USA 111(43): 15502-15507.
    • (2014) Proc Natl Acad Sci USA , vol.111 , Issue.43 , pp. 15502-15507
    • Lefrançais, E.1
  • 40
    • 84937869139 scopus 로고    scopus 로고
    • Pediatric severe asthma with fungal sensitization is mediated by steroid-resistant IL-33
    • Castanhinha S, et al. (2015) Pediatric severe asthma with fungal sensitization is mediated by steroid-resistant IL-33. J Allergy Clin Immunol 136(2):312-22.e7.
    • (2015) J Allergy Clin Immunol , vol.136 , Issue.2 , pp. 227-312
    • Castanhinha, S.1
  • 41
    • 84883218243 scopus 로고    scopus 로고
    • IL-33 promotes airway remodeling in pediatric patients with severe steroid-resistant asthma
    • e13
    • Saglani S, et al. (2013) IL-33 promotes airway remodeling in pediatric patients with severe steroid-resistant asthma. J Allergy Clin Immunol 132(3):676-685.e13.
    • (2013) J Allergy Clin Immunol , vol.132 , Issue.3 , pp. 676-685
    • Saglani, S.1
  • 42
    • 77951672627 scopus 로고    scopus 로고
    • Accumulation of intraepithelial mast cells with a unique protease phenotype in T(H)2-high asthma
    • e8
    • Dougherty RH, et al. (2010) Accumulation of intraepithelial mast cells with a unique protease phenotype in T(H)2-high asthma. J Allergy Clin Immunol 125(5):1046-1053.e8.
    • (2010) J Allergy Clin Immunol , vol.125 , Issue.5 , pp. 1046-1053
    • Dougherty, R.H.1
  • 43
    • 0034907372 scopus 로고    scopus 로고
    • Omalizumab, anti-IgE recombinant humanized monoclonal antibody, for the treatment of severe allergic asthma
    • Busse W, et al. (2001) Omalizumab, anti-IgE recombinant humanized monoclonal antibody, for the treatment of severe allergic asthma. J Allergy Clin Immunol 108(2): 184-190.
    • (2001) J Allergy Clin Immunol , vol.108 , Issue.2 , pp. 184-190
    • Busse, W.1
  • 44
    • 0034881877 scopus 로고    scopus 로고
    • The anti-IgE antibody omalizumab reduces exacerbations and steroid requirement in allergic asthmatics
    • Solèr M, et al. (2001) The anti-IgE antibody omalizumab reduces exacerbations and steroid requirement in allergic asthmatics. Eur Respir J 18(2):254-261.
    • (2001) Eur Respir J , vol.18 , Issue.2 , pp. 254-261
    • Solèr, M.1
  • 45
    • 85006311038 scopus 로고    scopus 로고
    • ADEPT and U-biopred investigators 2016) longitudinally stable, clinically defined clusters of patients with asthma independently identified in the adept and u-biopred asthma studies
    • Loza MJ, et al.; ADEPT and U-BIOPRED Investigators (2016) Longitudinally stable, clinically defined clusters of patients with asthma independently identified in the ADEPT and U-BIOPRED asthma studies. Ann Am Thorac Soc 13(Suppl 1):S102-S103.
    • Ann Am Thorac Soc , vol.13 , pp. S102-S103
    • Loza, M.J.1
  • 46
    • 84939795095 scopus 로고    scopus 로고
    • TH2 and TH17 inflammatory pathways are reciprocally regulated in asthma
    • Choy DF, et al. (2015) TH2 and TH17 inflammatory pathways are reciprocally regulated in asthma. Sci Transl Med 7(301):301ra129.
    • (2015) Sci Transl Med , vol.7 , Issue.301 , pp. 129-301
    • Choy, D.F.1


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