메뉴 건너뛰기




Volumn 8, Issue NOV, 2017, Pages

Innate immunity to respiratory infection in early life

Author keywords

Infection; Innate immunity; Neonatal; Respiratory; Respiratory syncytial virus

Indexed keywords

ANTIGEN; CHEMOKINE RECEPTOR CCR4; CXCL2 CHEMOKINE; GROWTH FACTOR; INTERFERON; INTERLEUKIN 22; VACCINE;

EID: 85034108477     PISSN: None     EISSN: 16643224     Source Type: Journal    
DOI: 10.3389/fimmu.2017.01570     Document Type: Short Survey
Times cited : (40)

References (145)
  • 1
    • 84941178180 scopus 로고    scopus 로고
    • Global, regional, and national causes of child mortality in 2000-13, with projections to inform post-2015 priorities: an updated systematic analysis
    • Liu L, Oza S, Hogan D, Perin J, Rudan I, Lawn JE, et al. Global, regional, and national causes of child mortality in 2000-13, with projections to inform post-2015 priorities: an updated systematic analysis. Lancet (2015) 385(9966):430-40. doi:10.1016/S0140-6736(14)61698-6
    • (2015) Lancet , vol.385 , Issue.9966 , pp. 430-440
    • Liu, L.1    Oza, S.2    Hogan, D.3    Perin, J.4    Rudan, I.5    Lawn, J.E.6
  • 2
    • 84876285802 scopus 로고    scopus 로고
    • Global burden of childhood pneumonia and diarrhoea
    • Walker CLF, Rudan I, Liu L, Nair H, Theodoratou E, Bhutta ZA, et al. Global burden of childhood pneumonia and diarrhoea. Lancet (2013) 381(9875):1405-16. doi:10.1016/S0140-6736(13)60222-6
    • (2013) Lancet , vol.381 , Issue.9875 , pp. 1405-1416
    • Walker, C.L.F.1    Rudan, I.2    Liu, L.3    Nair, H.4    Theodoratou, E.5    Bhutta, Z.A.6
  • 3
    • 74249116206 scopus 로고    scopus 로고
    • Respiratory viral infections in infants: causes, clinical symptoms, virology, and immunology
    • Tregoning JS, Schwarze J. Respiratory viral infections in infants: causes, clinical symptoms, virology, and immunology. Clin Microbiol Rev (2010) 23(1):74-98. doi:10.1128/CMR.00032-09
    • (2010) Clin Microbiol Rev , vol.23 , Issue.1 , pp. 74-98
    • Tregoning, J.S.1    Schwarze, J.2
  • 5
    • 77951653074 scopus 로고    scopus 로고
    • Global burden of acute lower respiratory infections due to respiratory syncytial virus in young children: a systematic review and meta-analysis
    • Nair H, Nokes DJ, Gessner BD, Dherani M, Madhi SA, Singleton RJ, et al. Global burden of acute lower respiratory infections due to respiratory syncytial virus in young children: a systematic review and meta-analysis. Lancet (2010) 375(9725):1545-55. doi:10.1016/S0140-6736(10)60206-1
    • (2010) Lancet , vol.375 , Issue.9725 , pp. 1545-1555
    • Nair, H.1    Nokes, D.J.2    Gessner, B.D.3    Dherani, M.4    Madhi, S.A.5    Singleton, R.J.6
  • 7
    • 84954057636 scopus 로고    scopus 로고
    • Viral bronchiolitis in children
    • Meissner HC. Viral bronchiolitis in children. N Engl J Med (2016) 374(1):62-72. doi:10.1056/NEJMra1413456
    • (2016) N Engl J Med , vol.374 , Issue.1 , pp. 62-72
    • Meissner, H.C.1
  • 8
    • 69949111769 scopus 로고    scopus 로고
    • Burden of disease caused by Streptococcus pneumoniae in children younger than 5 years: global estimates
    • O'Brien KL, Wolfson LJ, Watt JP, Henkle E, Deloria-Knoll M, McCall N, et al. Burden of disease caused by Streptococcus pneumoniae in children younger than 5 years: global estimates. Lancet (2009) 374(9693):893-902. doi:10.1016/S0140-6736(09)61204-6
    • (2009) Lancet , vol.374 , Issue.9693 , pp. 893-902
    • O'Brien, K.L.1    Wolfson, L.J.2    Watt, J.P.3    Henkle, E.4    Deloria-Knoll, M.5    McCall, N.6
  • 9
    • 69949109911 scopus 로고    scopus 로고
    • Burden of disease caused by Haemophilus influenzae type b in children younger than 5 years: global estimates
    • Watt JP, Wolfson LJ, O'Brien KL, Henkle E, Deloria-Knoll M, McCall N, et al. Burden of disease caused by Haemophilus influenzae type b in children younger than 5 years: global estimates. Lancet (2009) 374(9693):903-11. doi:10.1016/S0140-6736(09)61203-4
    • (2009) Lancet , vol.374 , Issue.9693 , pp. 903-911
    • Watt, J.P.1    Wolfson, L.J.2    O'Brien, K.L.3    Henkle, E.4    Deloria-Knoll, M.5    McCall, N.6
  • 10
    • 84963579211 scopus 로고    scopus 로고
    • Vaccination in early life: standing up to the challenges
    • Mohr E, Siegrist C-A. Vaccination in early life: standing up to the challenges. Curr Opin Immunol (2016) 41:1-8. doi:10.1016/j.coi.2016.04.004
    • (2016) Curr Opin Immunol , vol.41 , pp. 1-8
    • Mohr, E.1    Siegrist, C.-A.2
  • 11
    • 85018554407 scopus 로고    scopus 로고
    • Group B streptococcus and respiratory syncytial virus immunisation during pregnancy: a landscape analysis
    • Heath PT, Culley FJ, Jones CE, Kampmann B, Le Doare K, Nunes MC, et al. Group B streptococcus and respiratory syncytial virus immunisation during pregnancy: a landscape analysis. Lancet Infect Dis (2017) 17(7):e223-34. doi:10.1016/S1473-3099(17)30232-3
    • (2017) Lancet Infect Dis , vol.17 , Issue.7 , pp. e223-e234
    • Heath, P.T.1    Culley, F.J.2    Jones, C.E.3    Kampmann, B.4    Le Doare, K.5    Nunes, M.C.6
  • 12
    • 84655176310 scopus 로고    scopus 로고
    • The impact of perinatal immune development on mucosal homeostasis and chronic inflammation
    • Renz H, Brandtzaeg P, Hornef M. The impact of perinatal immune development on mucosal homeostasis and chronic inflammation. Nat Rev Immunol (2011) 12(1):9-23. doi:10.1038/nri3112
    • (2011) Nat Rev Immunol , vol.12 , Issue.1 , pp. 9-23
    • Renz, H.1    Brandtzaeg, P.2    Hornef, M.3
  • 13
    • 85019015707 scopus 로고    scopus 로고
    • Lung homeostasis: influence of age, microbes, and the immune system
    • Lloyd CM, Marsland BJ. Lung homeostasis: influence of age, microbes, and the immune system. Immunity (2017) 46(4):549-61. doi:10.1016/j.immuni.2017.04.005
    • (2017) Immunity , vol.46 , Issue.4 , pp. 549-561
    • Lloyd, C.M.1    Marsland, B.J.2
  • 14
    • 85015657548 scopus 로고    scopus 로고
    • The microbiota of the respiratory tract: gatekeeper to respiratory health
    • Man WH, de Steenhuijsen Piters WAA, Bogaert D. The microbiota of the respiratory tract: gatekeeper to respiratory health. Nat Rev Microbiol (2017) 15(5):259-70. doi:10.1038/nrmicro.2017.14
    • (2017) Nat Rev Microbiol , vol.15 , Issue.5 , pp. 259-270
    • Man, W.H.1    de Steenhuijsen Piters, W.A.A.2    Bogaert, D.3
  • 15
    • 84916206478 scopus 로고    scopus 로고
    • Early respiratory microbiota composition determines bacterial succession patterns and respiratory health in children
    • Biesbroek G, Tsivtsivadze E, Sanders EAM, Montijn R, Veenhoven RH, Keijser BJF, et al. Early respiratory microbiota composition determines bacterial succession patterns and respiratory health in children. Am J Respir Crit Care Med (2014) 190(11):1283-92. doi:10.1164/rccm.201407-1240OC
    • (2014) Am J Respir Crit Care Med , vol.190 , Issue.11 , pp. 1283-1292
    • Biesbroek, G.1    Tsivtsivadze, E.2    Sanders, E.A.M.3    Montijn, R.4    Veenhoven, R.H.5    Keijser, B.J.F.6
  • 16
    • 84994812757 scopus 로고    scopus 로고
    • Nasopharyngeal microbiota, host transcriptome, and disease severity in children with respiratory syncytial virus infection
    • De Steenhuijsen Piters WAA, Heinonen S, Hasrat R, Bunsow E, Smith B, Suarez-Arrabal M-C, et al. Nasopharyngeal microbiota, host transcriptome, and disease severity in children with respiratory syncytial virus infection. Am J Respir Crit Care Med (2016) 194(9):1104-15. doi:10.1164/rccm.201602-0220OC
    • (2016) Am J Respir Crit Care Med , vol.194 , Issue.9 , pp. 1104-1115
    • De Steenhuijsen Piters, W.A.A.1    Heinonen, S.2    Hasrat, R.3    Bunsow, E.4    Smith, B.5    Suarez-Arrabal, M.-C.6
  • 18
    • 77958471150 scopus 로고    scopus 로고
    • Asthma and allergy patterns over 18 years after severe RSV bronchiolitis in the first year of life
    • Sigurs N, Aljassim F, Kjellman B, Robinson PD, Sigurbergsson F, Bjarnason R, et al. Asthma and allergy patterns over 18 years after severe RSV bronchiolitis in the first year of life. Thorax (2010) 65(12):1045-52. doi:10.1136/thx.2009.121582
    • (2010) Thorax , vol.65 , Issue.12 , pp. 1045-1052
    • Sigurs, N.1    Aljassim, F.2    Kjellman, B.3    Robinson, P.D.4    Sigurbergsson, F.5    Bjarnason, R.6
  • 19
    • 84926427192 scopus 로고    scopus 로고
    • TLR4 genotype and environmental LPS mediate RSV bronchiolitis through Th2 polarization
    • Caballero MT, Serra ME, Acosta PL, Marzec J, Gibbons L, Salim M, et al. TLR4 genotype and environmental LPS mediate RSV bronchiolitis through Th2 polarization. J Clin Invest (2015) 125(2):571-82. doi:10.1172/JCI75183
    • (2015) J Clin Invest , vol.125 , Issue.2 , pp. 571-582
    • Caballero, M.T.1    Serra, M.E.2    Acosta, P.L.3    Marzec, J.4    Gibbons, L.5    Salim, M.6
  • 20
    • 73449092528 scopus 로고    scopus 로고
    • Early life origins of chronic obstructive pulmonary disease
    • Svanes C, Sunyer J, Plana E, Dharmage S, Heinrich J, Jarvis D, et al. Early life origins of chronic obstructive pulmonary disease. Thorax (2010) 65(1):14-20. doi:10.1136/thx.2008.112136
    • (2010) Thorax , vol.65 , Issue.1 , pp. 14-20
    • Svanes, C.1    Sunyer, J.2    Plana, E.3    Dharmage, S.4    Heinrich, J.5    Jarvis, D.6
  • 21
    • 0029005697 scopus 로고
    • Do lower respiratory tract infections in early childhood cause chronic obstructive pulmonary disease?
    • Shaheen SO, Barker DJ, Holgate ST. Do lower respiratory tract infections in early childhood cause chronic obstructive pulmonary disease? Am J Respir Crit Care Med (1995) 151(5):1649-51. doi:10.1164/ajrccm/151.5_Pt_1.1649
    • (1995) Am J Respir Crit Care Med , vol.151 , Issue.5 , pp. 1649-1651
    • Shaheen, S.O.1    Barker, D.J.2    Holgate, S.T.3
  • 22
    • 84857118737 scopus 로고    scopus 로고
    • Early origins of chronic obstructive pulmonary disease
    • Narang I, Bush A. Early origins of chronic obstructive pulmonary disease. Semin Fetal Neonatal Med (2012) 17(2):112-8. doi:10.1016/j.siny.2012.01.002
    • (2012) Semin Fetal Neonatal Med , vol.17 , Issue.2 , pp. 112-118
    • Narang, I.1    Bush, A.2
  • 23
    • 85021732807 scopus 로고    scopus 로고
    • Childhood lung function predicts adult chronic obstructive pulmonary disease and asthma-chronic obstructive pulmonary disease overlap syndrome
    • Bui DS, Burgess JA, Lowe AJ, Perret JL, Lodge CJ, Bui M, et al. Childhood lung function predicts adult chronic obstructive pulmonary disease and asthma-chronic obstructive pulmonary disease overlap syndrome. Am J Respir Crit Care Med (2017) 196(1):39-46. doi:10.1164/rccm.201606-1272OC
    • (2017) Am J Respir Crit Care Med , vol.196 , Issue.1 , pp. 39-46
    • Bui, D.S.1    Burgess, J.A.2    Lowe, A.J.3    Perret, J.L.4    Lodge, C.J.5    Bui, M.6
  • 24
    • 67049118969 scopus 로고    scopus 로고
    • The origins of asthma and chronic obstructive pulmonary disease in early life
    • Martinez FD. The origins of asthma and chronic obstructive pulmonary disease in early life. Proc Am Thorac Soc (2009) 6(3):272-7. doi:10.1513/pats.200808-092RM
    • (2009) Proc Am Thorac Soc , vol.6 , Issue.3 , pp. 272-277
    • Martinez, F.D.1
  • 25
    • 34247588114 scopus 로고    scopus 로고
    • Innate immunity of the newborn: basic mechanisms and clinical correlates
    • Levy O. Innate immunity of the newborn: basic mechanisms and clinical correlates. Nat Rev Immunol (2007) 7(5):379-90. doi:10.1038/nri2075
    • (2007) Nat Rev Immunol , vol.7 , Issue.5 , pp. 379-390
    • Levy, O.1
  • 26
    • 61349097791 scopus 로고    scopus 로고
    • B-cell responses to vaccination at the extremes of age
    • Siegrist C-A, Aspinall R. B-cell responses to vaccination at the extremes of age. Nat Rev Immunol (2009) 9(3):185-94. doi:10.1038/nri2508
    • (2009) Nat Rev Immunol , vol.9 , Issue.3 , pp. 185-194
    • Siegrist, C.-A.1    Aspinall, R.2
  • 27
    • 84866373869 scopus 로고    scopus 로고
    • The impact of differential antiviral immunity in children and adults
    • Prendergast AJ, Klenerman P, Goulder PJR. The impact of differential antiviral immunity in children and adults. Nat Rev Immunol (2012) 12(9):636-48. doi:10.1038/nri3277
    • (2012) Nat Rev Immunol , vol.12 , Issue.9 , pp. 636-648
    • Prendergast, A.J.1    Klenerman, P.2    Goulder, P.J.R.3
  • 28
    • 85015771024 scopus 로고    scopus 로고
    • Protecting the newborn and young infant from infectious diseases: lessons from immune ontogeny
    • Kollmann TR, Kampmann B, Mazmanian SK, Marchant A, Levy O. Protecting the newborn and young infant from infectious diseases: lessons from immune ontogeny. Immunity (2017) 46(3):350-63. doi:10.1016/j.immuni.2017.03.009
    • (2017) Immunity , vol.46 , Issue.3 , pp. 350-363
    • Kollmann, T.R.1    Kampmann, B.2    Mazmanian, S.K.3    Marchant, A.4    Levy, O.5
  • 29
    • 84869228450 scopus 로고    scopus 로고
    • Innate immune function by Toll-like receptors: distinct responses in newborns and the elderly
    • Kollmann TR, Levy O, Montgomery RR, Goriely S. Innate immune function by Toll-like receptors: distinct responses in newborns and the elderly. Immunity (2012) 37(5):771-83. doi:10.1016/j.immuni.2012.10.014
    • (2012) Immunity , vol.37 , Issue.5 , pp. 771-783
    • Kollmann, T.R.1    Levy, O.2    Montgomery, R.R.3    Goriely, S.4
  • 31
    • 3142743111 scopus 로고    scopus 로고
    • Neonatal adaptive immunity comes of age
    • Adkins B, Leclerc C, Marshall-Clarke S. Neonatal adaptive immunity comes of age. Nat Rev Immunol (2004) 4(7):553-64. doi:10.1038/nri1394
    • (2004) Nat Rev Immunol , vol.4 , Issue.7 , pp. 553-564
    • Adkins, B.1    Leclerc, C.2    Marshall-Clarke, S.3
  • 32
    • 70449629815 scopus 로고    scopus 로고
    • Neonatal immunity: faulty T-helpers and the shortcomings of dendritic cells
    • Zaghouani H, Hoeman CM, Adkins B. Neonatal immunity: faulty T-helpers and the shortcomings of dendritic cells. Trends Immunol (2009) 30(12):585-91. doi:10.1016/j.it.2009.09.002
    • (2009) Trends Immunol , vol.30 , Issue.12 , pp. 585-591
    • Zaghouani, H.1    Hoeman, C.M.2    Adkins, B.3
  • 33
    • 79951596628 scopus 로고    scopus 로고
    • Challenges in infant immunity: implications for responses to infection and vaccines
    • PrabhuDas M, Adkins B, Gans H, King C, Levy O, Ramilo O, et al. Challenges in infant immunity: implications for responses to infection and vaccines. Nat Immunol (2011) 12(3):189-94. doi:10.1038/ni0311-189
    • (2011) Nat Immunol , vol.12 , Issue.3 , pp. 189-194
    • PrabhuDas, M.1    Adkins, B.2    Gans, H.3    King, C.4    Levy, O.5    Ramilo, O.6
  • 34
    • 69449097370 scopus 로고    scopus 로고
    • Pathophysiological features of asthma develop in parallel in house dust mite-exposed neonatal mice
    • Saglani S, Mathie SA, Gregory LG, Bell MJ, Bush A, Lloyd CM. Pathophysiological features of asthma develop in parallel in house dust mite-exposed neonatal mice. Am J Respir Cell Mol Biol (2009) 41(3):281-9. doi:10.1165/rcmb.2008-0396OC
    • (2009) Am J Respir Cell Mol Biol , vol.41 , Issue.3 , pp. 281-289
    • Saglani, S.1    Mathie, S.A.2    Gregory, L.G.3    Bell, M.J.4    Bush, A.5    Lloyd, C.M.6
  • 35
    • 84902201196 scopus 로고    scopus 로고
    • Lung microbiota promotes tolerance to allergens in neonates via PD-L1
    • Gollwitzer ES, Saglani S, Trompette A, Yadava K, Sherburn R, McCoy KD, et al. Lung microbiota promotes tolerance to allergens in neonates via PD-L1. Nat Med (2014) 20(6):642-7. doi:10.1038/nm.3568
    • (2014) Nat Med , vol.20 , Issue.6 , pp. 642-647
    • Gollwitzer, E.S.1    Saglani, S.2    Trompette, A.3    Yadava, K.4    Sherburn, R.5    McCoy, K.D.6
  • 36
    • 4644307506 scopus 로고    scopus 로고
    • Selective impairment of TLR-mediated innate immunity in human newborns: neonatal blood plasma reduces monocyte TNF-alpha induction by bacterial lipopeptides, lipopolysaccharide, and imiquimod, but preserves the response to R-848
    • Levy O, Zarember KA, Roy RM, Cywes C, Godowski PJ, Wessels MR. Selective impairment of TLR-mediated innate immunity in human newborns: neonatal blood plasma reduces monocyte TNF-alpha induction by bacterial lipopeptides, lipopolysaccharide, and imiquimod, but preserves the response to R-848. J Immunol (2004) 173(7):4627-34. doi:10.4049/jimmunol.173.7.4627
    • (2004) J Immunol , vol.173 , Issue.7 , pp. 4627-4634
    • Levy, O.1    Zarember, K.A.2    Roy, R.M.3    Cywes, C.4    Godowski, P.J.5    Wessels, M.R.6
  • 37
    • 73349130456 scopus 로고    scopus 로고
    • Neonatal innate TLR-mediated responses are distinct from those of adults
    • Kollmann TR, Crabtree J, Rein-Weston A, Blimkie D, Thommai F, Wang XY, et al. Neonatal innate TLR-mediated responses are distinct from those of adults. J Immunol (2009) 183(11):7150-60. doi:10.4049/jimmunol.0901481
    • (2009) J Immunol , vol.183 , Issue.11 , pp. 7150-7160
    • Kollmann, T.R.1    Crabtree, J.2    Rein-Weston, A.3    Blimkie, D.4    Thommai, F.5    Wang, X.Y.6
  • 38
    • 78649764135 scopus 로고    scopus 로고
    • Ontogeny of Toll-like receptor mediated cytokine responses of human blood mononuclear cells
    • Corbett NP, Blimkie D, Ho KC, Cai B, Sutherland DP, Kallos A, et al. Ontogeny of Toll-like receptor mediated cytokine responses of human blood mononuclear cells. PLoS One (2010) 5(11):e15041. doi:10.1371/journal.pone.0015041
    • (2010) PLoS One , vol.5 , Issue.11
    • Corbett, N.P.1    Blimkie, D.2    Ho, K.C.3    Cai, B.4    Sutherland, D.P.5    Kallos, A.6
  • 39
    • 70349777300 scopus 로고    scopus 로고
    • Skewed pattern of Toll-like receptor 4-mediated cytokine production in human neonatal blood: low LPS-induced IL-12p70 and high IL-10 persist throughout the first month of life
    • Belderbos ME, van Bleek GM, Levy O, Blanken MO, Houben ML, Schuijff L, et al. Skewed pattern of Toll-like receptor 4-mediated cytokine production in human neonatal blood: low LPS-induced IL-12p70 and high IL-10 persist throughout the first month of life. Clin Immunol (2009) 133(2):228-37. doi:10.1016/j.clim.2009.07.003
    • (2009) Clin Immunol , vol.133 , Issue.2 , pp. 228-237
    • Belderbos, M.E.1    van Bleek, G.M.2    Levy, O.3    Blanken, M.O.4    Houben, M.L.5    Schuijff, L.6
  • 40
    • 84860506235 scopus 로고    scopus 로고
    • IL1RL1 gene variants and nasopharyngeal IL1RL-a levels are associated with severe RSV bronchiolitis: a multicenter cohort study
    • Faber TE, Schuurhof A, Vonk A, Koppelman GH, Hennus MP, Kimpen JLL, et al. IL1RL1 gene variants and nasopharyngeal IL1RL-a levels are associated with severe RSV bronchiolitis: a multicenter cohort study. PLoS One (2012) 7(5):e34364. doi:10.1371/journal.pone.0034364
    • (2012) PLoS One , vol.7 , Issue.5
    • Faber, T.E.1    Schuurhof, A.2    Vonk, A.3    Koppelman, G.H.4    Hennus, M.P.5    Kimpen, J.L.L.6
  • 41
    • 34548475750 scopus 로고    scopus 로고
    • Genetic susceptibility to respiratory syncytial virus bronchiolitis is predominantly associated with innate immune genes
    • Janssen R, Bont L, Siezen CLE, Hodemaekers HM, Ermers MJ, Doornbos G, et al. Genetic susceptibility to respiratory syncytial virus bronchiolitis is predominantly associated with innate immune genes. J Infect Dis (2007) 196(6):826-34. doi:10.1086/520886
    • (2007) J Infect Dis , vol.196 , Issue.6 , pp. 826-834
    • Janssen, R.1    Bont, L.2    Siezen, C.L.E.3    Hodemaekers, H.M.4    Ermers, M.J.5    Doornbos, G.6
  • 42
    • 34250873851 scopus 로고    scopus 로고
    • TLR4 polymorphisms mediate impaired responses to respiratory syncytial virus and lipopolysaccharide
    • Tulic MK, Hurrelbrink RJ, Prêle CM, Laing IA, Upham JW, Le Souef P, et al. TLR4 polymorphisms mediate impaired responses to respiratory syncytial virus and lipopolysaccharide. J Immunol (2007) 179(1):132-40. doi:10.4049/jimmunol.179.1.132
    • (2007) J Immunol , vol.179 , Issue.1 , pp. 132-140
    • Tulic, M.K.1    Hurrelbrink, R.J.2    Prêle, C.M.3    Laing, I.A.4    Upham, J.W.5    Le Souef, P.6
  • 43
    • 85018309713 scopus 로고    scopus 로고
    • Protective and harmful immunity to RSV infection
    • Openshaw PJM, Chiu C, Culley FJ, Johansson C. Protective and harmful immunity to RSV infection. Annu Rev Immunol (2017) 35(1):501-32. doi:10.1146/annurev-immunol-051116-052206
    • (2017) Annu Rev Immunol , vol.35 , Issue.1 , pp. 501-532
    • Openshaw, P.J.M.1    Chiu, C.2    Culley, F.J.3    Johansson, C.4
  • 44
    • 79960121968 scopus 로고    scopus 로고
    • Infectious diseases in patients with IRAK-4, MyD88, NEMO, or IκBα deficiency
    • Picard C, Casanova J-L, Puel A. Infectious diseases in patients with IRAK-4, MyD88, NEMO, or IκBα deficiency. Clin Microbiol Rev (2011) 24(3):490-7. doi:10.1128/CMR.00001-11
    • (2011) Clin Microbiol Rev , vol.24 , Issue.3 , pp. 490-497
    • Picard, C.1    Casanova, J.-L.2    Puel, A.3
  • 45
    • 84893652705 scopus 로고    scopus 로고
    • Alveolar macrophages: plasticity in a tissue-specific context
    • Hussell T, Bell TJ. Alveolar macrophages: plasticity in a tissue-specific context. Nat Rev Immunol (2014) 14(2):81-93. doi:10.1038/nri3600
    • (2014) Nat Rev Immunol , vol.14 , Issue.2 , pp. 81-93
    • Hussell, T.1    Bell, T.J.2
  • 46
    • 0029145314 scopus 로고
    • Lymphocyte subsets in bronchoalveolar lavage fluid of children without bronchopulmonary disease
    • Ratjen F, Bredendiek M, Zheng L, Brendel M, Costabel U. Lymphocyte subsets in bronchoalveolar lavage fluid of children without bronchopulmonary disease. Am J Respir Crit Care Med (1995) 152(1):174-8. doi:10.1164/ajrccm.152.1.7599820
    • (1995) Am J Respir Crit Care Med , vol.152 , Issue.1 , pp. 174-178
    • Ratjen, F.1    Bredendiek, M.2    Zheng, L.3    Brendel, M.4    Costabel, U.5
  • 47
    • 0028852074 scopus 로고
    • Role of bronchoalveolar lavage in children with lung disease
    • Riedler J, Grigg J, Robertson CF. Role of bronchoalveolar lavage in children with lung disease. Eur Respir J (1995) 8(10):1725-30. doi:10.1183/09031936.95.08101725
    • (1995) Eur Respir J , vol.8 , Issue.10 , pp. 1725-1730
    • Riedler, J.1    Grigg, J.2    Robertson, C.F.3
  • 48
    • 0033887219 scopus 로고    scopus 로고
    • Developmental airway cell biology. The 'normal' young child
    • Grigg J, Riedler J. Developmental airway cell biology. The 'normal' young child. Am J Respir Crit Care Med (2000) 162(2 Pt 2):S52-5. doi:10.1164/ajrccm.162.supplement_1.maic-14
    • (2000) Am J Respir Crit Care Med , vol.162 , Issue.2 , pp. S52-S55
    • Grigg, J.1    Riedler, J.2
  • 49
    • 0027970614 scopus 로고
    • Differential cytology of bronchoalveolar lavage fluid in normal children
    • Ratjen F, Bredendiek M, Brendel M, Meltzer J, Costabel U. Differential cytology of bronchoalveolar lavage fluid in normal children. Eur Respir J (1994) 7(10):1865-70. doi:10.1183/09031936.94.07101865
    • (1994) Eur Respir J , vol.7 , Issue.10 , pp. 1865-1870
    • Ratjen, F.1    Bredendiek, M.2    Brendel, M.3    Meltzer, J.4    Costabel, U.5
  • 51
    • 84954359892 scopus 로고    scopus 로고
    • Early-life compartmentalization of human T cell differentiation and regulatory function in mucosal and lymphoid tissues
    • Thome JJC, Bickham KL, Ohmura Y, Kubota M, Matsuoka N, Gordon C, et al. Early-life compartmentalization of human T cell differentiation and regulatory function in mucosal and lymphoid tissues. Nat Med (2016) 22(1):72-7. doi:10.1038/nm.4008
    • (2016) Nat Med , vol.22 , Issue.1 , pp. 72-77
    • Thome, J.J.C.1    Bickham, K.L.2    Ohmura, Y.3    Kubota, M.4    Matsuoka, N.5    Gordon, C.6
  • 52
    • 84988851006 scopus 로고    scopus 로고
    • Airway CD8(+) T cells are associated with lung injury during infant viral respiratory tract infection
    • Connors TJ, Ravindranath TM, Bickham KL, Gordon CL, Zhang F, Levin B, et al. Airway CD8(+) T cells are associated with lung injury during infant viral respiratory tract infection. Am J Respir Cell Mol Biol (2016) 54(6):822-30. doi:10.1165/rcmb.2015-0297OC
    • (2016) Am J Respir Cell Mol Biol , vol.54 , Issue.6 , pp. 822-830
    • Connors, T.J.1    Ravindranath, T.M.2    Bickham, K.L.3    Gordon, C.L.4    Zhang, F.5    Levin, B.6
  • 53
    • 85015777170 scopus 로고    scopus 로고
    • Dendritic cells display subset and tissue-specific maturation dynamics over human life
    • Granot T, Senda T, Carpenter DJ, Matsuoka N, Weiner J, Gordon CL, et al. Dendritic cells display subset and tissue-specific maturation dynamics over human life. Immunity (2017) 46(3):504-15. doi:10.1016/j.immuni.2017.02.019
    • (2017) Immunity , vol.46 , Issue.3 , pp. 504-515
    • Granot, T.1    Senda, T.2    Carpenter, D.J.3    Matsuoka, N.4    Weiner, J.5    Gordon, C.L.6
  • 54
    • 0032694891 scopus 로고    scopus 로고
    • Alveolar macrophage immaturity in infants and young children
    • Grigg J, Riedler J, Robertson CF, Boyle W, Uren S. Alveolar macrophage immaturity in infants and young children. Eur Respir J (1999) 14(5):1198-205. doi:10.1183/09031936.99.14511989
    • (1999) Eur Respir J , vol.14 , Issue.5 , pp. 1198-1205
    • Grigg, J.1    Riedler, J.2    Robertson, C.F.3    Boyle, W.4    Uren, S.5
  • 55
    • 84870296822 scopus 로고    scopus 로고
    • Early infection with respiratory syncytial virus impairs regulatory T cell function and increases susceptibility to allergic asthma
    • Krishnamoorthy N, Khare A, Oriss TB, Raundhal M, Morse C, Yarlagadda M, et al. Early infection with respiratory syncytial virus impairs regulatory T cell function and increases susceptibility to allergic asthma. Nat Med (2012) 18(10):1525-30. doi:10.1038/nm.2896
    • (2012) Nat Med , vol.18 , Issue.10 , pp. 1525-1530
    • Krishnamoorthy, N.1    Khare, A.2    Oriss, T.B.3    Raundhal, M.4    Morse, C.5    Yarlagadda, M.6
  • 56
    • 84855272559 scopus 로고    scopus 로고
    • Neonatal CD8 T-cell hierarchy is distinct from adults and is influenced by intrinsic T cell properties in respiratory syncytial virus infected mice
    • Ruckwardt TJ, Malloy AMW, Gostick E, Price DA, Dash P, McClaren JL, et al. Neonatal CD8 T-cell hierarchy is distinct from adults and is influenced by intrinsic T cell properties in respiratory syncytial virus infected mice. PLoS Pathog (2011) 7(12):e1002377. doi:10.1371/journal.ppat.1002377
    • (2011) PLoS Pathog , vol.7 , Issue.12
    • Ruckwardt, T.J.1    Malloy, A.M.W.2    Gostick, E.3    Price, D.A.4    Dash, P.5    McClaren, J.L.6
  • 57
    • 84921957499 scopus 로고    scopus 로고
    • Interleukin-8 (CXCL8) production is a signatory T cell effector function of human newborn infants
    • Gibbons D, Fleming P, Virasami A, Michel M-L, Sebire NJ, Costeloe K, et al. Interleukin-8 (CXCL8) production is a signatory T cell effector function of human newborn infants. Nat Med (2014) 20(10):1206-10. doi:10.1038/nm.3670
    • (2014) Nat Med , vol.20 , Issue.10 , pp. 1206-1210
    • Gibbons, D.1    Fleming, P.2    Virasami, A.3    Michel, M.-L.4    Sebire, N.J.5    Costeloe, K.6
  • 58
    • 85013935391 scopus 로고    scopus 로고
    • Respiratory syncytial virus infects regulatory B cells in human neonates via chemokine receptor CX3CR1 and promotes lung disease severity
    • Zhivaki D, Lemoine S, Lim A, Morva A, Vidalain P-O, Schandene L, et al. Respiratory syncytial virus infects regulatory B cells in human neonates via chemokine receptor CX3CR1 and promotes lung disease severity. Immunity (2017) 46(2):301-14. doi:10.1016/j.immuni.2017.01.010
    • (2017) Immunity , vol.46 , Issue.2 , pp. 301-314
    • Zhivaki, D.1    Lemoine, S.2    Lim, A.3    Morva, A.4    Vidalain, P.-O.5    Schandene, L.6
  • 59
    • 0035340762 scopus 로고    scopus 로고
    • Neonatal T cells in an adult lung environment are competent to resolve Pneumocystis carinii pneumonia
    • Qureshi MH, Garvy BA. Neonatal T cells in an adult lung environment are competent to resolve Pneumocystis carinii pneumonia. J Immunol (2001) 166(9):5704-11. doi:10.4049/jimmunol.166.9.5704
    • (2001) J Immunol , vol.166 , Issue.9 , pp. 5704-5711
    • Qureshi, M.H.1    Garvy, B.A.2
  • 60
    • 0034547966 scopus 로고    scopus 로고
    • Delayed inflammatory response to Pneumocystis carinii infection in neonatal mice is due to an inadequate lung environment
    • Garvy BA, Qureshi MH. Delayed inflammatory response to Pneumocystis carinii infection in neonatal mice is due to an inadequate lung environment. J Immunol (2000) 165(11):6480-6. doi:10.4049/jimmunol.165.11.6480
    • (2000) J Immunol , vol.165 , Issue.11 , pp. 6480-6486
    • Garvy, B.A.1    Qureshi, M.H.2
  • 61
    • 80053164804 scopus 로고    scopus 로고
    • Neonatal lung immune responses show a shift of cytokines and transcription factors toward Th2 and a deficit in conventional and plasmacytoid dendritic cells
    • Roux X, Remot A, Petit-Camurdan A, Nahori M-A, Kiefer-Biasizzo H, Marchal G, et al. Neonatal lung immune responses show a shift of cytokines and transcription factors toward Th2 and a deficit in conventional and plasmacytoid dendritic cells. Eur J Immunol (2011) 41(10):2852-61. doi:10.1002/eji.201041224
    • (2011) Eur J Immunol , vol.41 , Issue.10 , pp. 2852-2861
    • Roux, X.1    Remot, A.2    Petit-Camurdan, A.3    Nahori, M.-A.4    Kiefer-Biasizzo, H.5    Marchal, G.6
  • 62
    • 0029148411 scopus 로고
    • Defective regional immunity in the respiratory tract of neonates is attributable to hyporesponsiveness of local dendritic cells to activation signals
    • Nelson DJ, Holt PG. Defective regional immunity in the respiratory tract of neonates is attributable to hyporesponsiveness of local dendritic cells to activation signals. J Immunol (1995) 155(7):3517-24
    • (1995) J Immunol , vol.155 , Issue.7 , pp. 3517-3524
    • Nelson, D.J.1    Holt, P.G.2
  • 63
    • 33745659823 scopus 로고    scopus 로고
    • Pulmonary dendritic cells isolated from neonatal and adult ovine lung tissue
    • Fach SJ, Brockmeier SL, Hobbs LA, Lehmkuhl HD, Sacco RE. Pulmonary dendritic cells isolated from neonatal and adult ovine lung tissue. Vet Immunol Immunopathol (2006) 112(3-4):171-82. doi:10.1016/j.vetimm.2006.02.012
    • (2006) Vet Immunol Immunopathol , vol.112 , Issue.3-4 , pp. 171-182
    • Fach, S.J.1    Brockmeier, S.L.2    Hobbs, L.A.3    Lehmkuhl, H.D.4    Sacco, R.E.5
  • 64
    • 84895766412 scopus 로고    scopus 로고
    • Quantitative and qualitative deficits in neonatal lung-migratory dendritic cells impact the generation of the CD8+ T cell response
    • Ruckwardt TJ, Malloy AMW, Morabito KM, Graham BS. Quantitative and qualitative deficits in neonatal lung-migratory dendritic cells impact the generation of the CD8+ T cell response. PLoS Pathog (2014) 10(2):e1003934. doi:10.1371/journal.ppat.1003934
    • (2014) PLoS Pathog , vol.10 , Issue.2
    • Ruckwardt, T.J.1    Malloy, A.M.W.2    Morabito, K.M.3    Graham, B.S.4
  • 65
    • 85038883767 scopus 로고    scopus 로고
    • Neonatal mice possess two phenotypically and functionally distinct lung-migratory CD103(+) dendritic cell populations following respiratory infection
    • Ruckwardt TJ, Morabito KM, Bar-Haim E, Nair D, Graham BS. Neonatal mice possess two phenotypically and functionally distinct lung-migratory CD103(+) dendritic cell populations following respiratory infection. Mucosal Immunol (2017). doi:10.1038/mi.2017.28
    • (2017) Mucosal Immunol
    • Ruckwardt, T.J.1    Morabito, K.M.2    Bar-Haim, E.3    Nair, D.4    Graham, B.S.5
  • 66
    • 85006963151 scopus 로고    scopus 로고
    • Pulmonary dendritic cell subsets shape the respiratory syncytial virus-specific CD8+ T cell immunodominance hierarchy in neonates
    • Malloy AMW, Ruckwardt TJ, Morabito KM, Lau-Kilby AW, Graham BS. Pulmonary dendritic cell subsets shape the respiratory syncytial virus-specific CD8+ T cell immunodominance hierarchy in neonates. J Immunol (2017) 198(1):394-403. doi:10.4049/jimmunol.1600486
    • (2017) J Immunol , vol.198 , Issue.1 , pp. 394-403
    • Malloy, A.M.W.1    Ruckwardt, T.J.2    Morabito, K.M.3    Lau-Kilby, A.W.4    Graham, B.S.5
  • 67
    • 63149132590 scopus 로고    scopus 로고
    • Regulatory T cells promote early influx of CD8+ T cells in the lungs of respiratory syncytial virus-infected mice and diminish immunodominance disparities
    • Ruckwardt TJ, Bonaparte KL, Nason MC, Graham BS. Regulatory T cells promote early influx of CD8+ T cells in the lungs of respiratory syncytial virus-infected mice and diminish immunodominance disparities. J Virol (2009) 83(7):3019-28. doi:10.1128/JVI.00036-09
    • (2009) J Virol , vol.83 , Issue.7 , pp. 3019-3028
    • Ruckwardt, T.J.1    Bonaparte, K.L.2    Nason, M.C.3    Graham, B.S.4
  • 68
    • 80051570891 scopus 로고    scopus 로고
    • Dysregulation of allergic airway inflammation in the absence of microbial colonization
    • Herbst T, Sichelstiel A, Schär C, Yadava K, Bürki K, Cahenzli J, et al. Dysregulation of allergic airway inflammation in the absence of microbial colonization. Am J Respir Crit Care Med (2011) 184(2):198-205. doi:10.1164/rccm.201010-1574OC
    • (2011) Am J Respir Crit Care Med , vol.184 , Issue.2 , pp. 198-205
    • Herbst, T.1    Sichelstiel, A.2    Schär, C.3    Yadava, K.4    Bürki, K.5    Cahenzli, J.6
  • 69
    • 84904891710 scopus 로고    scopus 로고
    • Limited type I interferons and plasmacytoid dendritic cells during neonatal respiratory syncytial virus infection permit immunopathogenesis upon reinfection
    • Cormier SA, Shrestha B, Saravia J, Lee GI, Shen L, DeVincenzo JP, et al. Limited type I interferons and plasmacytoid dendritic cells during neonatal respiratory syncytial virus infection permit immunopathogenesis upon reinfection. J Virol (2014) 88(16):9350-60. doi:10.1128/JVI.00818-14
    • (2014) J Virol , vol.88 , Issue.16 , pp. 9350-9360
    • Cormier, S.A.1    Shrestha, B.2    Saravia, J.3    Lee, G.I.4    Shen, L.5    DeVincenzo, J.P.6
  • 70
    • 84876361438 scopus 로고    scopus 로고
    • Division of labor between lung dendritic cells and macrophages in the defense against pulmonary infections
    • Guilliams M, Lambrecht BN, Hammad H. Division of labor between lung dendritic cells and macrophages in the defense against pulmonary infections. Mucosal Immunol (2013) 6(3):464-73. doi:10.1038/mi.2013.14
    • (2013) Mucosal Immunol , vol.6 , Issue.3 , pp. 464-473
    • Guilliams, M.1    Lambrecht, B.N.2    Hammad, H.3
  • 71
    • 72849113090 scopus 로고    scopus 로고
    • Lung interstitial macrophages alter dendritic cell functions to prevent airway allergy in mice
    • Bedoret D, Wallemacq H, Marichal T, Desmet C, Quesada Calvo F, Henry E, et al. Lung interstitial macrophages alter dendritic cell functions to prevent airway allergy in mice. J Clin Invest (2009) 119(12):3723-38. doi:10.1172/JCI39717
    • (2009) J Clin Invest , vol.119 , Issue.12 , pp. 3723-3738
    • Bedoret, D.1    Wallemacq, H.2    Marichal, T.3    Desmet, C.4    Quesada Calvo, F.5    Henry, E.6
  • 72
    • 85015735121 scopus 로고    scopus 로고
    • Exposure to bacterial CpG DNA protects from airway allergic inflammation by expanding regulatory lung interstitial macrophages
    • Sabatel C, Radermecker C, Fievez L, Paulissen G, Chakarov S, Fernandes C, et al. Exposure to bacterial CpG DNA protects from airway allergic inflammation by expanding regulatory lung interstitial macrophages. Immunity (2017) 46(3):457-73. doi:10.1016/j.immuni.2017.02.016
    • (2017) Immunity , vol.46 , Issue.3 , pp. 457-473
    • Sabatel, C.1    Radermecker, C.2    Fievez, L.3    Paulissen, G.4    Chakarov, S.5    Fernandes, C.6
  • 73
    • 0021203789 scopus 로고
    • Alveolar macrophages in perinatal infants
    • Alenghat E, Esterly JR. Alveolar macrophages in perinatal infants. Pediatrics (1984) 74(2):221-3
    • (1984) Pediatrics , vol.74 , Issue.2 , pp. 221-223
    • Alenghat, E.1    Esterly, J.R.2
  • 74
    • 84885454468 scopus 로고    scopus 로고
    • Alveolar macrophages develop from fetal monocytes that differentiate into long-lived cells in the first week of life via GM-CSF
    • Guilliams M, De Kleer I, Henri S, Post S, Vanhoutte L, De Prijck S, et al. Alveolar macrophages develop from fetal monocytes that differentiate into long-lived cells in the first week of life via GM-CSF. J Exp Med (2013) 210(10):1977-92. doi:10.1084/jem.20131199
    • (2013) J Exp Med , vol.210 , Issue.10 , pp. 1977-1992
    • Guilliams, M.1    De Kleer, I.2    Henri, S.3    Post, S.4    Vanhoutte, L.5    De Prijck, S.6
  • 75
    • 0033746721 scopus 로고    scopus 로고
    • Role of alveolar macrophages in innate immunity in neonates: evidence for selective lipopolysaccharide binding protein production by rat neonatal alveolar macrophages
    • Lee PT, Holt PG, McWilliam AS. Role of alveolar macrophages in innate immunity in neonates: evidence for selective lipopolysaccharide binding protein production by rat neonatal alveolar macrophages. Am J Respir Cell Mol Biol (2000) 23(5):652-61. doi:10.1165/ajrcmb.23.5.4016
    • (2000) Am J Respir Cell Mol Biol , vol.23 , Issue.5 , pp. 652-661
    • Lee, P.T.1    Holt, P.G.2    McWilliam, A.S.3
  • 76
    • 34447287401 scopus 로고    scopus 로고
    • Exogenous heat-killed Escherichia coli improves alveolar macrophage activity and reduces Pneumocystis carinii lung burden in infant mice
    • Empey KM, Hollifield M, Garvy BA. Exogenous heat-killed Escherichia coli improves alveolar macrophage activity and reduces Pneumocystis carinii lung burden in infant mice. Infect Immun (2007) 75(7):3382-93. doi:10.1128/IAI.00174-07
    • (2007) Infect Immun , vol.75 , Issue.7 , pp. 3382-3393
    • Empey, K.M.1    Hollifield, M.2    Garvy, B.A.3
  • 77
    • 77953620384 scopus 로고    scopus 로고
    • Differential expression of cytokine transcripts in neonatal and adult ovine alveolar macrophages in response to respiratory syncytial virus or toll-like receptor ligation
    • Fach SJ, Olivier A, Gallup JM, Waters TE, Ackermann MR, Lehmkuhl HD, et al. Differential expression of cytokine transcripts in neonatal and adult ovine alveolar macrophages in response to respiratory syncytial virus or toll-like receptor ligation. Vet Immunol Immunopathol (2010) 136(1-2):55-64. doi:10.1016/j.vetimm.2010.02.008
    • (2010) Vet Immunol Immunopathol , vol.136 , Issue.1-2 , pp. 55-64
    • Fach, S.J.1    Olivier, A.2    Gallup, J.M.3    Waters, T.E.4    Ackermann, M.R.5    Lehmkuhl, H.D.6
  • 78
    • 84864802021 scopus 로고    scopus 로고
    • Alveolar macrophages in neonatal mice are inherently unresponsive to Pneumocystis murina infection
    • Kurkjian C, Hollifield M, Lines JL, Rogosky A, Empey KM, Qureshi M, et al. Alveolar macrophages in neonatal mice are inherently unresponsive to Pneumocystis murina infection. Infect Immun (2012) 80(8):2835-46. doi:10.1128/IAI.05707-11
    • (2012) Infect Immun , vol.80 , Issue.8 , pp. 2835-2846
    • Kurkjian, C.1    Hollifield, M.2    Lines, J.L.3    Rogosky, A.4    Empey, K.M.5    Qureshi, M.6
  • 79
    • 82655189435 scopus 로고    scopus 로고
    • Impaired neonatal macrophage phagocytosis is not explained by overproduction of prostaglandin E2
    • Ballinger MN, Peters-Golden M, Moore BB. Impaired neonatal macrophage phagocytosis is not explained by overproduction of prostaglandin E2. Respir Res (2011) 12:155. doi:10.1186/1465-9921-12-155
    • (2011) Respir Res , vol.12 , pp. 155
    • Ballinger, M.N.1    Peters-Golden, M.2    Moore, B.B.3
  • 80
    • 0023874056 scopus 로고
    • The ontogeny of pulmonary defenses: alveolar macrophage function in neonatal and juvenile rhesus monkeys
    • Kurland G, Cheung AT, Miller ME, Ayin SA, Cho MM, Ford EW. The ontogeny of pulmonary defenses: alveolar macrophage function in neonatal and juvenile rhesus monkeys. Pediatr Res (1988) 23(3):293-7. doi:10.1203/00006450-198803000-00013
    • (1988) Pediatr Res , vol.23 , Issue.3 , pp. 293-297
    • Kurland, G.1    Cheung, A.T.2    Miller, M.E.3    Ayin, S.A.4    Cho, M.M.5    Ford, E.W.6
  • 81
    • 7044237210 scopus 로고    scopus 로고
    • Passive immunization of neonatal mice against Pneumocystis carinii f. sp. muris enhances control of infection without stimulating inflammation
    • Empey KM, Hollifield M, Schuer K, Gigliotti F, Garvy BA. Passive immunization of neonatal mice against Pneumocystis carinii f. sp. muris enhances control of infection without stimulating inflammation. Infect Immun (2004) 72(11):6211-20. doi:10.1128/IAI.72.11.6211-6220.2004
    • (2004) Infect Immun , vol.72 , Issue.11 , pp. 6211-6220
    • Empey, K.M.1    Hollifield, M.2    Schuer, K.3    Gigliotti, F.4    Garvy, B.A.5
  • 82
    • 84863707107 scopus 로고    scopus 로고
    • Stimulation of immature lung macrophages with intranasal interferon gamma in a novel neonatal mouse model of respiratory syncytial virus infection
    • Empey KM, Orend JG, Peebles RS, Egaña L, Norris KA, Oury TD, et al. Stimulation of immature lung macrophages with intranasal interferon gamma in a novel neonatal mouse model of respiratory syncytial virus infection. PLoS One (2012) 7(7):e40499. doi:10.1371/journal.pone.0040499
    • (2012) PLoS One , vol.7 , Issue.7
    • Empey, K.M.1    Orend, J.G.2    Peebles, R.S.3    Egaña, L.4    Norris, K.A.5    Oury, T.D.6
  • 83
    • 84926637156 scopus 로고    scopus 로고
    • Respiratory epithelial cells orchestrate pulmonary innate immunity
    • Whitsett JA, Alenghat T. Respiratory epithelial cells orchestrate pulmonary innate immunity. Nat Immunol (2015) 16(1):27-35. doi:10.1038/ni.3045
    • (2015) Nat Immunol , vol.16 , Issue.1 , pp. 27-35
    • Whitsett, J.A.1    Alenghat, T.2
  • 84
    • 84887057187 scopus 로고    scopus 로고
    • Innate immune response to LPS in airway epithelium is dependent on chronological age and antecedent exposures
    • Maniar-Hew K, Clay CC, Postlethwait EM, Evans MJ, Fontaine JH, Miller LA. Innate immune response to LPS in airway epithelium is dependent on chronological age and antecedent exposures. Am J Respir Cell Mol Biol (2013) 49(5):710-20. doi:10.1165/rcmb.2012-0321OC
    • (2013) Am J Respir Cell Mol Biol , vol.49 , Issue.5 , pp. 710-720
    • Maniar-Hew, K.1    Clay, C.C.2    Postlethwait, E.M.3    Evans, M.J.4    Fontaine, J.H.5    Miller, L.A.6
  • 85
    • 84901981502 scopus 로고    scopus 로고
    • Enhanced viral replication and modulated innate immune responses in infant airway epithelium following H1N1 infection
    • Clay CC, Reader JR, Gerriets JE, Wang TT, Harrod KS, Miller LA. Enhanced viral replication and modulated innate immune responses in infant airway epithelium following H1N1 infection. J Virol (2014) 88(13):7412-25. doi:10.1128/JVI.00188-14
    • (2014) J Virol , vol.88 , Issue.13 , pp. 7412-7425
    • Clay, C.C.1    Reader, J.R.2    Gerriets, J.E.3    Wang, T.T.4    Harrod, K.S.5    Miller, L.A.6
  • 87
    • 0024574604 scopus 로고
    • Production of interferon in respiratory syncytial virus bronchiolitis
    • Isaacs D. Production of interferon in respiratory syncytial virus bronchiolitis. Arch Dis Child (1989) 64(1):92-5. doi:10.1136/adc.64.1.92
    • (1989) Arch Dis Child , vol.64 , Issue.1 , pp. 92-95
    • Isaacs, D.1
  • 88
    • 84888990746 scopus 로고    scopus 로고
    • Whole blood gene expression profiles to assess pathogenesis and disease severity in infants with respiratory syncytial virus infection
    • Mejias A, Dimo B, Suarez NM, Garcia C, Suarez-Arrabal MC, Jartti T, et al. Whole blood gene expression profiles to assess pathogenesis and disease severity in infants with respiratory syncytial virus infection. PLoS Med (2013) 10(11):e1001549. doi:10.1371/journal.pmed.1001549
    • (2013) PLoS Med , vol.10 , Issue.11
    • Mejias, A.1    Dimo, B.2    Suarez, N.M.3    Garcia, C.4    Suarez-Arrabal, M.C.5    Jartti, T.6
  • 89
    • 84859452124 scopus 로고    scopus 로고
    • In vitro modeling of respiratory syncytial virus infection of pediatric bronchial epithelium, the primary target of infection in vivo
    • Villenave R, Thavagnanam S, Sarlang S, Parker J, Douglas I, Skibinski G, et al. In vitro modeling of respiratory syncytial virus infection of pediatric bronchial epithelium, the primary target of infection in vivo. Proc Natl Acad Sci U S A (2012) 109(13):5040-5. doi:10.1073/pnas.1110203109
    • (2012) Proc Natl Acad Sci U S A , vol.109 , Issue.13 , pp. 5040-5045
    • Villenave, R.1    Thavagnanam, S.2    Sarlang, S.3    Parker, J.4    Douglas, I.5    Skibinski, G.6
  • 90
    • 84855189083 scopus 로고    scopus 로고
    • Primary airway epithelial cultures from children are highly permissive to respiratory syncytial virus infection
    • Fonceca AM, Flanagan BF, Trinick R, Smyth RL, McNamara PS. Primary airway epithelial cultures from children are highly permissive to respiratory syncytial virus infection. Thorax (2012) 67(1):42-8. doi:10.1136/thoraxjnl-2011-200131
    • (2012) Thorax , vol.67 , Issue.1 , pp. 42-48
    • Fonceca, A.M.1    Flanagan, B.F.2    Trinick, R.3    Smyth, R.L.4    McNamara, P.S.5
  • 91
    • 84877115919 scopus 로고    scopus 로고
    • Respiratory syncytial virus interaction with human airway epithelium
    • Villenave R, Shields MD, Power UF. Respiratory syncytial virus interaction with human airway epithelium. Trends Microbiol (2013) 21(5):238-44. doi:10.1016/j.tim.2013.02.004
    • (2013) Trends Microbiol , vol.21 , Issue.5 , pp. 238-244
    • Villenave, R.1    Shields, M.D.2    Power, U.F.3
  • 92
    • 84949895414 scopus 로고    scopus 로고
    • Induction and antagonism of antiviral responses in respiratory syncytial virus-infected pediatric airway epithelium
    • Villenave R, Broadbent L, Douglas I, Lyons JD, Coyle PV, Teng MN, et al. Induction and antagonism of antiviral responses in respiratory syncytial virus-infected pediatric airway epithelium. J Virol (2015) 89(24):12309-18. doi:10.1128/JVI.02119-15
    • (2015) J Virol , vol.89 , Issue.24 , pp. 12309-12318
    • Villenave, R.1    Broadbent, L.2    Douglas, I.3    Lyons, J.D.4    Coyle, P.V.5    Teng, M.N.6
  • 93
    • 80052181676 scopus 로고    scopus 로고
    • Type-III interferon, not type-I, is the predominant interferon induced by respiratory viruses in nasal epithelial cells
    • Okabayashi T, Kojima T, Masaki T, Yokota S-I, Imaizumi T, Tsutsumi H, et al. Type-III interferon, not type-I, is the predominant interferon induced by respiratory viruses in nasal epithelial cells. Virus Res (2011) 160(1-2):360-6. doi:10.1016/j.virusres.2011.07.011
    • (2011) Virus Res , vol.160 , Issue.1-2 , pp. 360-366
    • Okabayashi, T.1    Kojima, T.2    Masaki, T.3    Yokota, S.-I.4    Imaizumi, T.5    Tsutsumi, H.6
  • 94
    • 17044371439 scopus 로고    scopus 로고
    • Production of chemokines in the lungs of infants with severe respiratory syncytial virus bronchiolitis
    • McNamara PS, Flanagan BF, Hart CA, Smyth RL. Production of chemokines in the lungs of infants with severe respiratory syncytial virus bronchiolitis. J Infect Dis (2005) 191(8):1225-32. doi:10.1086/428855
    • (2005) J Infect Dis , vol.191 , Issue.8 , pp. 1225-1232
    • McNamara, P.S.1    Flanagan, B.F.2    Hart, C.A.3    Smyth, R.L.4
  • 95
    • 84871361832 scopus 로고    scopus 로고
    • Respiratory syncytial virus infection of airway epithelial cells, in vivo and in vitro, supports pulmonary antibody responses by inducing expression of the B cell differentiation factor BAFF
    • McNamara PS, Fonceca AM, Howarth D, Correia JB, Slupsky JR, Trinick RE, et al. Respiratory syncytial virus infection of airway epithelial cells, in vivo and in vitro, supports pulmonary antibody responses by inducing expression of the B cell differentiation factor BAFF. Thorax (2013) 68(1):76-81. doi:10.1136/thoraxjnl-2012-202288
    • (2013) Thorax , vol.68 , Issue.1 , pp. 76-81
    • McNamara, P.S.1    Fonceca, A.M.2    Howarth, D.3    Correia, J.B.4    Slupsky, J.R.5    Trinick, R.E.6
  • 96
    • 84946055529 scopus 로고    scopus 로고
    • Respiratory syncytial virus disease is mediated by age-variable IL-33
    • Saravia J, You D, Shrestha B, Jaligama S, Siefker D, Lee GI, et al. Respiratory syncytial virus disease is mediated by age-variable IL-33. PLoS Pathog (2015) 11(10):e1005217. doi:10.1371/journal.ppat.1005217
    • (2015) PLoS Pathog , vol.11 , Issue.10
    • Saravia, J.1    You, D.2    Shrestha, B.3    Jaligama, S.4    Siefker, D.5    Lee, G.I.6
  • 97
    • 85008225342 scopus 로고    scopus 로고
    • Serum cathelicidin, nasopharyngeal microbiota, and disease severity among infants hospitalized with bronchiolitis
    • Hasegawa K, Mansbach JM, Ajami NJ, Petrosino JF, Freishtat RJ, Teach SJ, et al. Serum cathelicidin, nasopharyngeal microbiota, and disease severity among infants hospitalized with bronchiolitis. J Allergy Clin Immunol (2017) 139(4):1383.e-6.e. doi:10.1016/j.jaci.2016.09.037
    • (2017) J Allergy Clin Immunol , vol.139 , Issue.4 , pp. 1383e-1386e
    • Hasegawa, K.1    Mansbach, J.M.2    Ajami, N.J.3    Petrosino, J.F.4    Freishtat, R.J.5    Teach, S.J.6
  • 98
    • 12444337486 scopus 로고    scopus 로고
    • Expression and activity of beta-defensins and LL-37 in the developing human lung
    • Starner TD, Agerberth B, Gudmundsson GH, McCray PB. Expression and activity of beta-defensins and LL-37 in the developing human lung. J Immunol (2005) 174(3):1608-15. doi:10.4049/jimmunol.174.3.1608
    • (2005) J Immunol , vol.174 , Issue.3 , pp. 1608-1615
    • Starner, T.D.1    Agerberth, B.2    Gudmundsson, G.H.3    McCray, P.B.4
  • 99
    • 0036528903 scopus 로고    scopus 로고
    • Increased levels of antimicrobial peptides in tracheal aspirates of newborn infants during infection
    • Schaller-Bals S, Schulze A, Bals R. Increased levels of antimicrobial peptides in tracheal aspirates of newborn infants during infection. Am J Respir Crit Care Med (2002) 165(7):992-5. doi:10.1164/ajrccm.165.7.200110-020
    • (2002) Am J Respir Crit Care Med , vol.165 , Issue.7 , pp. 992-995
    • Schaller-Bals, S.1    Schulze, A.2    Bals, R.3
  • 100
    • 0032929360 scopus 로고    scopus 로고
    • Surfactant protein-A enhances respiratory syncytial virus clearance in vivo
    • LeVine AM, Gwozdz J, Stark J, Bruno M, Whitsett J, Korfhagen T. Surfactant protein-A enhances respiratory syncytial virus clearance in vivo. J Clin Invest (1999) 103(7):1015-21. doi:10.1172/JCI5849
    • (1999) J Clin Invest , vol.103 , Issue.7 , pp. 1015-1021
    • LeVine, A.M.1    Gwozdz, J.2    Stark, J.3    Bruno, M.4    Whitsett, J.5    Korfhagen, T.6
  • 101
    • 84883646355 scopus 로고    scopus 로고
    • The innate immune system of the perinatal lung and responses to respiratory syncytial virus infection
    • Derscheid RJ, Ackermann MR. The innate immune system of the perinatal lung and responses to respiratory syncytial virus infection. Vet Pathol (2013) 50(5):827-41. doi:10.1177/0300985813480216
    • (2013) Vet Pathol , vol.50 , Issue.5 , pp. 827-841
    • Derscheid, R.J.1    Ackermann, M.R.2
  • 102
    • 84989328833 scopus 로고    scopus 로고
    • Antimicrobial proteins and peptides in early life: ontogeny and translational opportunities
    • Battersby AJ, Khara J, Wright VJ, Levy O, Kampmann B. Antimicrobial proteins and peptides in early life: ontogeny and translational opportunities. Front Immunol (2016) 7:309. doi:10.3389/fimmu.2016.00309
    • (2016) Front Immunol , vol.7 , pp. 309
    • Battersby, A.J.1    Khara, J.2    Wright, V.J.3    Levy, O.4    Kampmann, B.5
  • 103
    • 84865718292 scopus 로고    scopus 로고
    • Prospective multicenter study of children with bronchiolitis requiring mechanical ventilation
    • Mansbach JM, Piedra PA, Stevenson MD, Sullivan AF, Forgey TF, Clark S, et al. Prospective multicenter study of children with bronchiolitis requiring mechanical ventilation. Pediatrics (2012) 130(3):e492-500. doi:10.1542/peds.2012-0444
    • (2012) Pediatrics , vol.130 , Issue.3 , pp. e492-e500
    • Mansbach, J.M.1    Piedra, P.A.2    Stevenson, M.D.3    Sullivan, A.F.4    Forgey, T.F.5    Clark, S.6
  • 105
    • 84962575116 scopus 로고    scopus 로고
    • Cathelicidins have direct antiviral activity against respiratory syncytial virus in vitro and protective function in vivo in mice and humans
    • Currie SM, Gwyer Findlay E, McFarlane AJ, Fitch PM, Böttcher B, Colegrave N, et al. Cathelicidins have direct antiviral activity against respiratory syncytial virus in vitro and protective function in vivo in mice and humans. J Immunol (2016) 196(6):2699-710. doi:10.4049/jimmunol.1502478
    • (2016) J Immunol , vol.196 , Issue.6 , pp. 2699-2710
    • Currie, S.M.1    Gwyer Findlay, E.2    McFarlane, A.J.3    Fitch, P.M.4    Böttcher, B.5    Colegrave, N.6
  • 106
    • 84883431889 scopus 로고    scopus 로고
    • The human cathelicidin LL-37 has antiviral activity against respiratory syncytial virus
    • Currie SM, Findlay EG, McHugh BJ, Mackellar A, Man T, Macmillan D, et al. The human cathelicidin LL-37 has antiviral activity against respiratory syncytial virus. PLoS One (2013) 8(8):e73659. doi:10.1371/journal.pone.0073659
    • (2013) PLoS One , vol.8 , Issue.8
    • Currie, S.M.1    Findlay, E.G.2    McHugh, B.J.3    Mackellar, A.4    Man, T.5    Macmillan, D.6
  • 107
    • 84953410451 scopus 로고    scopus 로고
    • Human cathelicidin, LL-37, inhibits respiratory syncytial virus infection in polarized airway epithelial cells
    • Harcourt JL, McDonald M, Svoboda P, Pohl J, Tatti K, Haynes LM. Human cathelicidin, LL-37, inhibits respiratory syncytial virus infection in polarized airway epithelial cells. BMC Res Notes (2016) 9(1):11. doi:10.1186/s13104-015-1836-y
    • (2016) BMC Res Notes , vol.9 , Issue.1 , pp. 11
    • Harcourt, J.L.1    McDonald, M.2    Svoboda, P.3    Pohl, J.4    Tatti, K.5    Haynes, L.M.6
  • 108
    • 84922615231 scopus 로고    scopus 로고
    • Impaired gamma delta T cell-derived IL-17A and inflammasome activation during early respiratory syncytial virus infection in infants
    • Huang H, Saravia J, You D, Shaw AJ, Cormier SA. Impaired gamma delta T cell-derived IL-17A and inflammasome activation during early respiratory syncytial virus infection in infants. Immunol Cell Biol (2015) 93(2):126-35. doi:10.1038/icb.2014.79
    • (2015) Immunol Cell Biol , vol.93 , Issue.2 , pp. 126-135
    • Huang, H.1    Saravia, J.2    You, D.3    Shaw, A.J.4    Cormier, S.A.5
  • 109
    • 84937869139 scopus 로고    scopus 로고
    • Pediatric severe asthma with fungal sensitization is mediated by steroid-resistant IL-33
    • Castanhinha S, Sherburn R, Walker S, Gupta A, Bossley CJ, Buckley J, et al. Pediatric severe asthma with fungal sensitization is mediated by steroid-resistant IL-33. J Allergy Clin Immunol (2015) 136(2):312.e-22.e. doi:10.1016/j.jaci.2015.01.016
    • (2015) J Allergy Clin Immunol , vol.136 , Issue.2 , pp. 312e-322e
    • Castanhinha, S.1    Sherburn, R.2    Walker, S.3    Gupta, A.4    Bossley, C.J.5    Buckley, J.6
  • 110
    • 84860216630 scopus 로고    scopus 로고
    • Microbial exposure during early life has persistent effects on natural killer T cell function
    • Olszak T, An D, Zeissig S, Vera MP, Richter J, Franke A, et al. Microbial exposure during early life has persistent effects on natural killer T cell function. Science (2012) 336(6080):489-93. doi:10.1126/science.1219328
    • (2012) Science , vol.336 , Issue.6080 , pp. 489-493
    • Olszak, T.1    An, D.2    Zeissig, S.3    Vera, M.P.4    Richter, J.5    Franke, A.6
  • 111
    • 85012883069 scopus 로고    scopus 로고
    • Intestinal commensal bacteria mediate lung mucosal immunity and promote resistance of newborn mice to infection
    • Gray J, Oehrle K, Worthen G, Alenghat T, Whitsett J, Deshmukh H. Intestinal commensal bacteria mediate lung mucosal immunity and promote resistance of newborn mice to infection. Sci Transl Med (2017) 9(376):eaaf9412. doi:10.1126/scitranslmed.aaf9412
    • (2017) Sci Transl Med , vol.9 , Issue.376
    • Gray, J.1    Oehrle, K.2    Worthen, G.3    Alenghat, T.4    Whitsett, J.5    Deshmukh, H.6
  • 112
    • 0035193173 scopus 로고    scopus 로고
    • Ontogeny of Toll-like receptors Tlr2 and Tlr4 in mice
    • Harju K, Glumoff V, Hallman M. Ontogeny of Toll-like receptors Tlr2 and Tlr4 in mice. Pediatr Res (2001) 49(1):81-3. doi:10.1203/00006450-200101000-00018
    • (2001) Pediatr Res , vol.49 , Issue.1 , pp. 81-83
    • Harju, K.1    Glumoff, V.2    Hallman, M.3
  • 113
    • 17744392629 scopus 로고    scopus 로고
    • Expression of toll-like receptor 4 and endotoxin responsiveness in mice during perinatal period
    • Harju K, Ojaniemi M, Rounioja S, Glumoff V, Paananen R, Vuolteenaho R, et al. Expression of toll-like receptor 4 and endotoxin responsiveness in mice during perinatal period. Pediatr Res (2005) 57(5 Pt 1):644-8. doi:10.1203/01.PDR.0000156212.03459.A9
    • (2005) Pediatr Res , vol.57 , Issue.5 , pp. 644-648
    • Harju, K.1    Ojaniemi, M.2    Rounioja, S.3    Glumoff, V.4    Paananen, R.5    Vuolteenaho, R.6
  • 114
    • 77957280893 scopus 로고    scopus 로고
    • Selective Toll-like receptor expression in human fetal lung
    • Petrikin JE, Gaedigk R, Leeder JS, Truog WE. Selective Toll-like receptor expression in human fetal lung. Pediatr Res (2010) 68(4):335-8. doi:10.1203/PDR.0b013e3181ed1134
    • (2010) Pediatr Res , vol.68 , Issue.4 , pp. 335-338
    • Petrikin, J.E.1    Gaedigk, R.2    Leeder, J.S.3    Truog, W.E.4
  • 115
    • 83655211787 scopus 로고    scopus 로고
    • Reduced inflammation and altered innate response in neonates during paramyxoviral infection
    • Bhattacharya S, Beal BT, Janowski AM, Shornick LP. Reduced inflammation and altered innate response in neonates during paramyxoviral infection. Virol J (2011) 8:549. doi:10.1186/1743-422X-8-549
    • (2011) Virol J , vol.8 , pp. 549
    • Bhattacharya, S.1    Beal, B.T.2    Janowski, A.M.3    Shornick, L.P.4
  • 116
    • 0036936445 scopus 로고    scopus 로고
    • Relationships among specific viral pathogens, virus-induced interleukin-8, and respiratory symptoms in infancy
    • Gern JE, Martin MS, Anklam KA, Shen K, Roberg KA, Carlson-Dakes KT, et al. Relationships among specific viral pathogens, virus-induced interleukin-8, and respiratory symptoms in infancy. Pediatr Allergy Immunol (2002) 13(6):386-93. doi:10.1034/j.1399-3038.2002.01093.x
    • (2002) Pediatr Allergy Immunol , vol.13 , Issue.6 , pp. 386-393
    • Gern, J.E.1    Martin, M.S.2    Anklam, K.A.3    Shen, K.4    Roberg, K.A.5    Carlson-Dakes, K.T.6
  • 117
    • 0028802017 scopus 로고
    • Effects of endotoxin in the lungs of neonatal rats: age-dependent impairment of the inflammatory response
    • Martin TR, Ruzinski JT, Wilson CB, Skerrett SJ. Effects of endotoxin in the lungs of neonatal rats: age-dependent impairment of the inflammatory response. J Infect Dis (1995) 171(1):134-44. doi:10.1093/infdis/171.1.134
    • (1995) J Infect Dis , vol.171 , Issue.1 , pp. 134-144
    • Martin, T.R.1    Ruzinski, J.T.2    Wilson, C.B.3    Skerrett, S.J.4
  • 118
    • 0023841503 scopus 로고
    • Lung antibacterial defense mechanisms in infant and adult rats: implications for the pathogenesis of group B streptococcal infections in the neonatal lung
    • Martin TR, Rubens CE, Wilson CB. Lung antibacterial defense mechanisms in infant and adult rats: implications for the pathogenesis of group B streptococcal infections in the neonatal lung. J Infect Dis (1988) 157(1):91-100. doi:10.1093/infdis/157.1.91
    • (1988) J Infect Dis , vol.157 , Issue.1 , pp. 91-100
    • Martin, T.R.1    Rubens, C.E.2    Wilson, C.B.3
  • 120
    • 0025604983 scopus 로고
    • Impaired transendothelial migration by neonatal neutrophils: abnormalities of Mac-1 (CD11b/CD18)-dependent adherence reactions
    • Anderson DC, Rothlein R, Marlin SD, Krater SS, Smith CW. Impaired transendothelial migration by neonatal neutrophils: abnormalities of Mac-1 (CD11b/CD18)-dependent adherence reactions. Blood (1990) 76(12):2613-21
    • (1990) Blood , vol.76 , Issue.12 , pp. 2613-2621
    • Anderson, D.C.1    Rothlein, R.2    Marlin, S.D.3    Krater, S.S.4    Smith, C.W.5
  • 121
    • 0027478793 scopus 로고
    • Diminished actin polymerization by neutrophils from newborn infants
    • Harris MC, Shalit M, Southwick FS. Diminished actin polymerization by neutrophils from newborn infants. Pediatr Res (1993) 33(1):27-31. doi:10.1203/00006450-199301000-00006
    • (1993) Pediatr Res , vol.33 , Issue.1 , pp. 27-31
    • Harris, M.C.1    Shalit, M.2    Southwick, F.S.3
  • 122
    • 0035050169 scopus 로고    scopus 로고
    • Leucocyte populations in respiratory syncytial virus-induced bronchiolitis
    • Smith PK, Wang SZ, Dowling KD, Forsyth KD. Leucocyte populations in respiratory syncytial virus-induced bronchiolitis. J Paediatr Child Health (2001) 37(2):146-51. doi:10.1046/j.1440-1754.2001.00618.x
    • (2001) J Paediatr Child Health , vol.37 , Issue.2 , pp. 146-151
    • Smith, P.K.1    Wang, S.Z.2    Dowling, K.D.3    Forsyth, K.D.4
  • 123
    • 0141636306 scopus 로고    scopus 로고
    • Bronchoalveolar lavage cellularity in infants with severe respiratory syncytial virus bronchiolitis
    • McNamara PS, Ritson P, Selby A, Hart CA, Smyth RL. Bronchoalveolar lavage cellularity in infants with severe respiratory syncytial virus bronchiolitis. Arch Dis Child (2003) 88(10):922-6. doi:10.1136/adc.88.10.922
    • (2003) Arch Dis Child , vol.88 , Issue.10 , pp. 922-926
    • McNamara, P.S.1    Ritson, P.2    Selby, A.3    Hart, C.A.4    Smyth, R.L.5
  • 124
    • 0032844232 scopus 로고    scopus 로고
    • IL-8 and neutrophil elastase levels in the respiratory tract of infants with RSV bronchiolitis
    • Abu-Harb M, Bell F, Finn A, Rao WH, Nixon L, Shale D, et al. IL-8 and neutrophil elastase levels in the respiratory tract of infants with RSV bronchiolitis. Eur Respir J (1999) 14(1):139-43. doi:10.1034/j.1399-3003.1999.14a23.x
    • (1999) Eur Respir J , vol.14 , Issue.1 , pp. 139-143
    • Abu-Harb, M.1    Bell, F.2    Finn, A.3    Rao, W.H.4    Nixon, L.5    Shale, D.6
  • 125
    • 0028153311 scopus 로고
    • Analysis of cells obtained by bronchial lavage of infants with respiratory syncytial virus infection
    • Everard ML, Swarbrick A, Wrightham M, McIntyre J, Dunkley C, James PD, et al. Analysis of cells obtained by bronchial lavage of infants with respiratory syncytial virus infection. Arch Dis Child (1994) 71(5):428-32. doi:10.1136/adc.71.5.428
    • (1994) Arch Dis Child , vol.71 , Issue.5 , pp. 428-432
    • Everard, M.L.1    Swarbrick, A.2    Wrightham, M.3    McIntyre, J.4    Dunkley, C.5    James, P.D.6
  • 126
    • 0036340815 scopus 로고    scopus 로고
    • Chemokines and inflammation in the nasal passages of infants with respiratory syncytial virus bronchiolitis
    • Noah TL, Ivins SS, Murphy P, Kazachkova I, Moats-Staats B, Henderson FW. Chemokines and inflammation in the nasal passages of infants with respiratory syncytial virus bronchiolitis. Clin Immunol (2002) 104(1):86-95. doi:10.1006/clim.2002.5248
    • (2002) Clin Immunol , vol.104 , Issue.1 , pp. 86-95
    • Noah, T.L.1    Ivins, S.S.2    Murphy, P.3    Kazachkova, I.4    Moats-Staats, B.5    Henderson, F.W.6
  • 127
    • 84988927923 scopus 로고    scopus 로고
    • Robust cytokine and chemokine response in nasopharyngeal secretions: association with decreased severity in children with physician diagnosed bronchiolitis
    • Nicholson EG, Schlegel C, Garofalo RP, Mehta R, Scheffler M, Mei M, et al. Robust cytokine and chemokine response in nasopharyngeal secretions: association with decreased severity in children with physician diagnosed bronchiolitis. J Infect Dis (2016) 214(4):649-55. doi:10.1093/infdis/jiw191
    • (2016) J Infect Dis , vol.214 , Issue.4 , pp. 649-655
    • Nicholson, E.G.1    Schlegel, C.2    Garofalo, R.P.3    Mehta, R.4    Scheffler, M.5    Mei, M.6
  • 128
    • 0029797590 scopus 로고    scopus 로고
    • Susceptibility to Pneumocystis carinii infection: host responses of neonatal mice from immune or naive mothers and of immune or naive adults
    • Garvy BA, Harmsen AG. Susceptibility to Pneumocystis carinii infection: host responses of neonatal mice from immune or naive mothers and of immune or naive adults. Infect Immun (1996) 64(10):3987-92
    • (1996) Infect Immun , vol.64 , Issue.10 , pp. 3987-3992
    • Garvy, B.A.1    Harmsen, A.G.2
  • 129
    • 84869008952 scopus 로고    scopus 로고
    • Preexposure to CpG protects against the delayed effects of neonatal respiratory syncytial virus infection
    • Yamaguchi Y, Harker JA, Wang B, Openshaw PJ, Tregoning JS, Culley FJ. Preexposure to CpG protects against the delayed effects of neonatal respiratory syncytial virus infection. J Virol (2012) 86(19):10456-61. doi:10.1128/JVI.01082-12
    • (2012) J Virol , vol.86 , Issue.19 , pp. 10456-10461
    • Yamaguchi, Y.1    Harker, J.A.2    Wang, B.3    Openshaw, P.J.4    Tregoning, J.S.5    Culley, F.J.6
  • 131
    • 33646141491 scopus 로고    scopus 로고
    • Prenatal farm exposure is related to the expression of receptors of the innate immunity and to atopic sensitization in school-age children
    • Ege MJ, Bieli C, Frei R, van Strien RT, Riedler J, Ublagger E, et al. Prenatal farm exposure is related to the expression of receptors of the innate immunity and to atopic sensitization in school-age children. J Allergy Clin Immunol (2006) 117(4):817-23. doi:10.1016/j.jaci.2005.12.1307
    • (2006) J Allergy Clin Immunol , vol.117 , Issue.4 , pp. 817-823
    • Ege, M.J.1    Bieli, C.2    Frei, R.3    van Strien, R.T.4    Riedler, J.5    Ublagger, E.6
  • 132
    • 0037136585 scopus 로고    scopus 로고
    • Environmental exposure to endotoxin and its relation to asthma in school-age children
    • Braun-Fahrländer C, Riedler J, Herz U, Eder W, Waser M, Grize L, et al. Environmental exposure to endotoxin and its relation to asthma in school-age children. N Engl J Med (2002) 347(12):869-77. doi:10.1056/NEJMoa020057
    • (2002) N Engl J Med , vol.347 , Issue.12 , pp. 869-877
    • Braun-Fahrländer, C.1    Riedler, J.2    Herz, U.3    Eder, W.4    Waser, M.5    Grize, L.6
  • 133
    • 84982085604 scopus 로고    scopus 로고
    • Innate immunity and asthma risk in amish and hutterite farm children
    • Stein MM, Hrusch CL, Gozdz J, Igartua C, Pivniouk V, Murray SE, et al. Innate immunity and asthma risk in amish and hutterite farm children. N Engl J Med (2016) 375(5):411-21. doi:10.1056/NEJMoa1508749
    • (2016) N Engl J Med , vol.375 , Issue.5 , pp. 411-421
    • Stein, M.M.1    Hrusch, C.L.2    Gozdz, J.3    Igartua, C.4    Pivniouk, V.5    Murray, S.E.6
  • 134
    • 84941102754 scopus 로고    scopus 로고
    • Farm dust and endotoxin protect against allergy through A20 induction in lung epithelial cells
    • Schuijs MJ, Willart MA, Vergote K, Gras D, Deswarte K, Ege MJ, et al. Farm dust and endotoxin protect against allergy through A20 induction in lung epithelial cells. Science (2015) 349(6252):1106-10. doi:10.1126/science.aac6623
    • (2015) Science , vol.349 , Issue.6252 , pp. 1106-1110
    • Schuijs, M.J.1    Willart, M.A.2    Vergote, K.3    Gras, D.4    Deswarte, K.5    Ege, M.J.6
  • 135
    • 84938791971 scopus 로고    scopus 로고
    • Risks of antibiotic exposures early in life on the developing microbiome
    • Schulfer A, Blaser MJ. Risks of antibiotic exposures early in life on the developing microbiome. PLoS Pathog (2015) 11(7):e1004903. doi:10.1371/journal.ppat.1004903
    • (2015) PLoS Pathog , vol.11 , Issue.7
    • Schulfer, A.1    Blaser, M.J.2
  • 138
    • 80052654856 scopus 로고    scopus 로고
    • NF-κB signaling in fetal lung macrophages disrupts airway morphogenesis
    • Blackwell TS, Hipps AN, Yamamoto Y, Han W, Barham WJ, Ostrowski MC, et al. NF-κB signaling in fetal lung macrophages disrupts airway morphogenesis. J Immunol (2011) 187(5):2740-7. doi:10.4049/jimmunol.1101495
    • (2011) J Immunol , vol.187 , Issue.5 , pp. 2740-2747
    • Blackwell, T.S.1    Hipps, A.N.2    Yamamoto, Y.3    Han, W.4    Barham, W.J.5    Ostrowski, M.C.6
  • 139
    • 19544373805 scopus 로고    scopus 로고
    • Toll-like receptor signaling inhibits structural development of the distal fetal mouse lung
    • Prince LS, Dieperink HI, Okoh VO, Fierro-Perez GA, Lallone RL. Toll-like receptor signaling inhibits structural development of the distal fetal mouse lung. Dev Dyn (2005) 233(2):553-61. doi:10.1002/dvdy.20362
    • (2005) Dev Dyn , vol.233 , Issue.2 , pp. 553-561
    • Prince, L.S.1    Dieperink, H.I.2    Okoh, V.O.3    Fierro-Perez, G.A.4    Lallone, R.L.5
  • 140
    • 33846069779 scopus 로고    scopus 로고
    • IL-1beta disrupts postnatal lung morphogenesis in the mouse
    • Bry K, Whitsett JA, Lappalainen U. IL-1beta disrupts postnatal lung morphogenesis in the mouse. Am J Respir Cell Mol Biol (2007) 36(1):32-42. doi:10.1165/rcmb.2006-0116OC
    • (2007) Am J Respir Cell Mol Biol , vol.36 , Issue.1 , pp. 32-42
    • Bry, K.1    Whitsett, J.A.2    Lappalainen, U.3
  • 141
    • 80051817023 scopus 로고    scopus 로고
    • Intersections between pulmonary development and disease
    • Whitsett JA, Haitchi HM, Maeda Y. Intersections between pulmonary development and disease. Am J Respir Crit Care Med (2011) 184(4):401-6. doi:10.1164/rccm.201103-0495PP
    • (2011) Am J Respir Crit Care Med , vol.184 , Issue.4 , pp. 401-406
    • Whitsett, J.A.1    Haitchi, H.M.2    Maeda, Y.3
  • 143
    • 84875866913 scopus 로고    scopus 로고
    • M2 macrophage polarisation is associated with alveolar formation during postnatal lung development
    • Jones CV, Williams TM, Walker KA, Dickinson H, Sakkal S, Rumballe BA, et al. M2 macrophage polarisation is associated with alveolar formation during postnatal lung development. Respir Res (2013) 14:41. doi:10.1186/1465-9921-14-41
    • (2013) Respir Res , vol.14 , pp. 41
    • Jones, C.V.1    Williams, T.M.2    Walker, K.A.3    Dickinson, H.4    Sakkal, S.5    Rumballe, B.A.6
  • 144
    • 84890101527 scopus 로고    scopus 로고
    • Foxa2 regulates leukotrienes to inhibit Th2-mediated pulmonary inflammation
    • Tang X, Liu XJ, Tian C, Su Q, Lei Y, Wu Q, et al. Foxa2 regulates leukotrienes to inhibit Th2-mediated pulmonary inflammation. Am J Respir Cell Mol Biol (2013) 49(6):960-70. doi:10.1165/rcmb.2013-0122OC
    • (2013) Am J Respir Cell Mol Biol , vol.49 , Issue.6 , pp. 960-970
    • Tang, X.1    Liu, X.J.2    Tian, C.3    Su, Q.4    Lei, Y.5    Wu, Q.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.