Exposure to Bacterial CpG DNA Protects from Airway Allergic Inflammation by Expanding Regulatory Lung Interstitial Macrophages

Immunity

Volumn 46, Issue 3, 2017, Pages 457-473

  Sabatel, Catherine ^a   Radermecker, Coraline ^a   Fievez, Laurence ^a   Paulissen, Genevieve ^a   Chakarov, Svetoslav ^b   Fernandes, Claudia ^a   Olivier, Sabine ^a   Toussaint, Marie ^c   Pirottin, Dimitri ^a   Xiao, Xue ^a   Quatresooz, Pascale ^a   Sirard, Jean Claude ^d   Cataldo, Didier ^a   Gillet, Laurent ^a   Bouabe, Hicham ^e   Desmet, Christophe J ^a   Ginhoux, Florent ^b   Marichal, Thomas ^a   Bureau, Fabrice ^a,f  

^a UNIVERSITY OF LIÈGE   (Belgium)

^b AGENCY FOR SCIENCE   (Singapore)

^c NATIONAL HEART AND LUNG INSTITUTE   (United Kingdom)

^d UNIV LILLE   (France)

^e BABRAHAM INSTITUTE   (United Kingdom)

^f Walloon Excellence in Life Sciences and Biotechnology   (Belgium)

Author keywords

asthma; CCR2; CpG; hygiene hypothesis; IL 10; lung; monocytes; regulatory macrophages; spleen; TLR9

Indexed keywords

CHEMOKINE RECEPTOR CCR2; CPG OLIGODEOXYNUCLEOTIDE; INTERLEUKIN 10; TOLL LIKE RECEPTOR 9; BACTERIAL DNA; CPG-OLIGONUCLEOTIDE; OLIGODEOXYRIBONUCLEOTIDE;

ADOPTIVE TRANSFER; ALLERGIC AIRWAY INFLAMMATION; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ASTHMA; BACTERIUM; BONE MARROW; CELL EXPANSION; CELL INFILTRATION; CONTROLLED STUDY; CYTOKINE PRODUCTION; ENVIRONMENTAL EXPOSURE; LUNG INTERSTITIAL MACROPHAGE; MACROPHAGE; MONOCYTE; MOUSE; NONHUMAN; PRIORITY JOURNAL; RISK REDUCTION; SPLEEN; ANIMAL; C57BL MOUSE; DISEASE MODEL; FLOW CYTOMETRY; HYPERSENSITIVITY; IMMUNOLOGY; KNOCKOUT MOUSE; LUNG ALVEOLUS MACROPHAGE; MACROPHAGE ACTIVATION; NEUTROPHIL CHEMOTAXIS; RESPIRATORY TRACT ALLERGY;

ANIMALS; CHEMOTAXIS, LEUKOCYTE; DISEASE MODELS, ANIMAL; DNA, BACTERIAL; FLOW CYTOMETRY; HYPERSENSITIVITY; MACROPHAGE ACTIVATION; MACROPHAGES; MACROPHAGES, ALVEOLAR; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; OLIGODEOXYRIBONUCLEOTIDES; RESPIRATORY HYPERSENSITIVITY; SPLEEN;

EID: 85015735121     PISSN: 10747613     EISSN: 10974180     Source Type: Journal    
DOI: 10.1016/j.immuni.2017.02.016     Document Type: Article

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