메뉴 건너뛰기




Volumn 19, Issue 12, 2017, Pages

HDL Cholesterol Metabolism and the Risk of CHD: New Insights from Human Genetics

Author keywords

Atherosclerosis; Cholesterol efflux capacity; Coronary heart disease (CHD); Exome array genotyping; Exome sequencing; Genome wide association study (GWAS); Genomics; High density lipoprotein cholesterol (HDL C); Reverse cholesterol transport; Single nucleotide polymorphism (SNP); Targeted resequencing

Indexed keywords

CHOLESTEROL ESTER TRANSFER PROTEIN; HIGH DENSITY LIPOPROTEIN CHOLESTEROL; PHOSPHATIDYLCHOLINE STEROL ACYLTRANSFERASE; SCAVENGER RECEPTOR BI; BIOLOGICAL MARKER;

EID: 85032800146     PISSN: 15233782     EISSN: 15343170     Source Type: Journal    
DOI: 10.1007/s11886-017-0940-0     Document Type: Review
Times cited : (79)

References (158)
  • 1
    • 0037154285 scopus 로고    scopus 로고
    • Simple scoring scheme for calculating the risk of acute coronary events based on the 10-year follow-up of the prospective cardiovascular Munster (PROCAM) study
    • PID: 11804985
    • Assmann G, Cullen P, Schulte H. Simple scoring scheme for calculating the risk of acute coronary events based on the 10-year follow-up of the prospective cardiovascular Munster (PROCAM) study. Circulation. 2002;105:310–5.
    • (2002) Circulation , vol.105 , pp. 310-315
    • Assmann, G.1    Cullen, P.2    Schulte, H.3
  • 2
    • 70450081001 scopus 로고    scopus 로고
    • Major lipids, apolipoproteins, and risk of vascular disease
    • PID: 19903920
    • Di Angelantonio E, Sarwar N, Perry P, et al. Major lipids, apolipoproteins, and risk of vascular disease. JAMA. 2009;302:1993–2000.
    • (2009) JAMA , vol.302 , pp. 1993-2000
    • Di Angelantonio, E.1    Sarwar, N.2    Perry, P.3
  • 3
    • 0000463969 scopus 로고
    • Risk factors in coronary heart disease. an evaluation of several serum lipids as predictors of coronary heart disease; the Framingham study
    • COI: 1:CAS:528:DyaF2MXns1ygtw%3D%3D, PID: 14233810
    • Kannel WB, Dawber TR, Friedman GD, Glennon WE, McNamara PM. Risk factors in coronary heart disease. an evaluation of several serum lipids as predictors of coronary heart disease; the Framingham study. Ann Intern Med. 1964;61:888–99.
    • (1964) Ann Intern Med , vol.61 , pp. 888-899
    • Kannel, W.B.1    Dawber, T.R.2    Friedman, G.D.3    Glennon, W.E.4    McNamara, P.M.5
  • 4
    • 79953192995 scopus 로고    scopus 로고
    • HDL and cardiovascular disease: atherogenic and atheroprotective mechanisms
    • COI: 1:CAS:528:DC%2BC3MXjvVKns7s%3D, PID: 21304474
    • Navab M, Reddy ST, Van Lenten BJ, Fogelman AM. HDL and cardiovascular disease: atherogenic and atheroprotective mechanisms. Nat Rev Cardiol. 2011;8:222–32.
    • (2011) Nat Rev Cardiol , vol.8 , pp. 222-232
    • Navab, M.1    Reddy, S.T.2    Van Lenten, B.J.3    Fogelman, A.M.4
  • 5
    • 85027694919 scopus 로고    scopus 로고
    • Mendelian randomization in cardiometabolic disease: challenges in evaluating causality
    • Holmes MV, Ala-Korpela M, Smith GD. Mendelian randomization in cardiometabolic disease: challenges in evaluating causality. Nat Rev Cardiol. 2017;
    • (2017) Nat Rev Cardiol
    • Holmes, M.V.1    Ala-Korpela, M.2    Smith, G.D.3
  • 6
    • 84864845456 scopus 로고    scopus 로고
    • Plasma HDL cholesterol and risk of myocardial infarction: a mendelian randomisation study
    • COI: 1:CAS:528:DC%2BC38Xnt1Cmsrc%3D
    • Voight BF, Peloso GM, Orho-Melander M, et al. Plasma HDL cholesterol and risk of myocardial infarction: a mendelian randomisation study. Lancet (London, England). 2012;380:572–80.
    • (2012) Lancet (London, England) , vol.380 , pp. 572-580
    • Voight, B.F.1    Peloso, G.M.2    Orho-Melander, M.3
  • 7
    • 85019790381 scopus 로고    scopus 로고
    • Evacetrapib and cardiovascular outcomes in high-risk vascular disease
    • PID: 28514624
    • Lincoff AM, Nicholls SJ, Riesmeyer JS, et al. Evacetrapib and cardiovascular outcomes in high-risk vascular disease. N Engl J Med. 2017;376:1933–42.
    • (2017) N Engl J Med , vol.376 , pp. 1933-1942
    • Lincoff, A.M.1    Nicholls, S.J.2    Riesmeyer, J.S.3
  • 8
    • 36348975228 scopus 로고    scopus 로고
    • Effects of torcetrapib in patients at high risk for coronary events
    • COI: 1:CAS:528:DC%2BD2sXhtlGns7bL, PID: 17984165
    • Barter PJ, Caulfield M, Eriksson M, et al. Effects of torcetrapib in patients at high risk for coronary events. N Engl J Med. 2007;357:2109–22.
    • (2007) N Engl J Med , vol.357 , pp. 2109-2122
    • Barter, P.J.1    Caulfield, M.2    Eriksson, M.3
  • 9
    • 84870045994 scopus 로고    scopus 로고
    • Effects of dalcetrapib in patients with a recent acute coronary syndrome
    • COI: 1:CAS:528:DC%2BC38XhslyltrvK, PID: 23126252
    • Schwartz GG, Olsson AG, Abt M, et al. Effects of dalcetrapib in patients with a recent acute coronary syndrome. N Engl J Med. 2012;367:2089–99.
    • (2012) N Engl J Med , vol.367 , pp. 2089-2099
    • Schwartz, G.G.1    Olsson, A.G.2    Abt, M.3
  • 10
    • 77956812723 scopus 로고    scopus 로고
    • Genetic causes of high and low serum HDL-cholesterol
    • COI: 1:CAS:528:DC%2BC3cXpvVOlur0%3D, PID: 20421590
    • Weissglas-Volkov D, Pajukanta P. Genetic causes of high and low serum HDL-cholesterol. J Lipid Res. 2010;51:2032–57.
    • (2010) J Lipid Res , vol.51 , pp. 2032-2057
    • Weissglas-Volkov, D.1    Pajukanta, P.2
  • 11
    • 58549109632 scopus 로고    scopus 로고
    • Plasma lipoproteins: genetic influences and clinical implications
    • COI: 1:CAS:528:DC%2BD1MXlvFCgsg%3D%3D, PID: 19139765
    • Hegele RA. Plasma lipoproteins: genetic influences and clinical implications. Nat Rev Genet. 2009;10:109–21.
    • (2009) Nat Rev Genet , vol.10 , pp. 109-121
    • Hegele, R.A.1
  • 12
    • 84889582851 scopus 로고    scopus 로고
    • Monogenic causes of elevated HDL cholesterol and implications for development of new therapeutics
    • COI: 1:CAS:528:DC%2BC3sXhvVGrsL%2FL, PID: 25374625
    • Larach DB, Cuchel M, Rader DJ. Monogenic causes of elevated HDL cholesterol and implications for development of new therapeutics. Clinical Lipidology. 2013;8:635–48.
    • (2013) Clinical Lipidology , vol.8 , pp. 635-648
    • Larach, D.B.1    Cuchel, M.2    Rader, D.J.3
  • 13
    • 84960897316 scopus 로고    scopus 로고
    • Rare variant in scavenger receptor BI raises HDL cholesterol and increases risk of coronary heart disease
    • COI: 1:CAS:528:DC%2BC28Xjs12gtrg%3D, This paper describes the paradoxical association of a loss-of-function mutation inSCARB1gene that confers incresed HDL-C but is associated with incresed CHD risk and supports the role of a functional SR-BI in HDL metabolism and RCT
    • • Zanoni P, Khetarpal SA, Larach DB, et al. Rare variant in scavenger receptor BI raises HDL cholesterol and increases risk of coronary heart disease. Science (New York, NY). 2016;351:1166–71. This paper describes the paradoxical association of a loss-of-function mutation in SCARB1 gene that confers incresed HDL-C but is associated with incresed CHD risk and supports the role of a functional SR-BI in HDL metabolism and RCT
    • (2016) Science (New York, NY) , vol.351 , pp. 1166-1171
    • Zanoni, P.1    Khetarpal, S.A.2    Larach, D.B.3
  • 14
    • 42349112088 scopus 로고    scopus 로고
    • Genome-wide association studies for complex traits: consensus, uncertainty and challenges
    • COI: 1:CAS:528:DC%2BD1cXkvVOhs7Y%3D, PID: 18398418
    • McCarthy MI, Abecasis GR, Cardon LR, et al. Genome-wide association studies for complex traits: consensus, uncertainty and challenges. Nat Rev Genet. 2008;9:356–69.
    • (2008) Nat Rev Genet , vol.9 , pp. 356-369
    • McCarthy, M.I.1    Abecasis, G.R.2    Cardon, L.R.3
  • 15
    • 58149335215 scopus 로고    scopus 로고
    • Genome-wide association studies: past, present and future
    • COI: 1:CAS:528:DC%2BD1cXhtlyjsrbK, PID: 18852196
    • McCarthy MI, Hirschhorn JN. Genome-wide association studies: past, present and future. Hum Mol Genet. 2008;17:R100–1.
    • (2008) Hum Mol Genet , vol.17 , pp. R100-R101
    • McCarthy, M.I.1    Hirschhorn, J.N.2
  • 16
    • 84867129109 scopus 로고    scopus 로고
    • Functional evaluation of genetic variation in complex human traits
    • COI: 1:CAS:528:DC%2BC38XhsVartr7I, PID: 22936690
    • Peters DT, Musunuru K. Functional evaluation of genetic variation in complex human traits. Hum Mol Genet. 2012;21:R18–23.
    • (2012) Hum Mol Genet , vol.21 , pp. R18-R23
    • Peters, D.T.1    Musunuru, K.2
  • 17
    • 84858783318 scopus 로고    scopus 로고
    • Finding genes and variants for lipid levels after genome-wide association analysis
    • COI: 1:CAS:528:DC%2BC38Xjslams74%3D, PID: 22418572
    • Willer CJ, Mohlke KL. Finding genes and variants for lipid levels after genome-wide association analysis. Curr Opin Lipidol. 2012;23:98–103.
    • (2012) Curr Opin Lipidol , vol.23 , pp. 98-103
    • Willer, C.J.1    Mohlke, K.L.2
  • 18
    • 85032816344 scopus 로고
    • Genetics of lipid traits: genome-wide approaches yield new biology and clues to causality in coronary artery disease
    • Khetarpal SA, Rader DJ. Genetics of lipid traits: genome-wide approaches yield new biology and clues to causality in coronary artery disease. Biochim Biophys Acta. 1842;2014:2010–20.
    • (1842) Biochim Biophys Acta , vol.2014 , pp. 2010-2020
    • Khetarpal, S.A.1    Rader, D.J.2
  • 19
    • 84881023348 scopus 로고    scopus 로고
    • Whole-genome sequence-based analysis of high-density lipoprotein cholesterol
    • COI: 1:CAS:528:DC%2BC3sXpsFSjtrw%3D, PID: 23770607
    • Morrison AC, Voorman A, Johnson AD, et al. Whole-genome sequence-based analysis of high-density lipoprotein cholesterol. Nat Genet. 2013;45:899–901.
    • (2013) Nat Genet , vol.45 , pp. 899-901
    • Morrison, A.C.1    Voorman, A.2    Johnson, A.D.3
  • 20
    • 84865693681 scopus 로고    scopus 로고
    • The metabochip, a custom genotyping array for genetic studies of metabolic, cardiovascular, and anthropometric traits
    • COI: 1:CAS:528:DC%2BC38XhtFKlurjE, PID: 22876189
    • Voight BF, Kang HM, Ding J, et al. The metabochip, a custom genotyping array for genetic studies of metabolic, cardiovascular, and anthropometric traits. PLoS Genet. 2012;8:e1002793.
    • (2012) PLoS Genet , vol.8
    • Voight, B.F.1    Kang, H.M.2    Ding, J.3
  • 21
    • 71249103564 scopus 로고    scopus 로고
    • Principal-component-based population structure adjustment in the North American Rheumatoid Arthritis Consortium data: impact of single-nucleotide polymorphism set and analysis method
    • PID: 20017972
    • Peloso GM, Timofeev N, Lunetta KL. Principal-component-based population structure adjustment in the North American Rheumatoid Arthritis Consortium data: impact of single-nucleotide polymorphism set and analysis method. BMC Proc. 2009;3(Suppl 7):S108.
    • (2009) BMC Proc , vol.3 , pp. S108
    • Peloso, G.M.1    Timofeev, N.2    Lunetta, K.L.3
  • 23
    • 67049137261 scopus 로고    scopus 로고
    • Mendelian randomization: nature's randomized trial in the post-genome era
    • COI: 1:CAS:528:DC%2BD1MXntFeru7w%3D, PID: 19509388
    • Thanassoulis G, O'Donnell CJ. Mendelian randomization: nature's randomized trial in the post-genome era. JAMA. 2009;301:2386–8.
    • (2009) JAMA , vol.301 , pp. 2386-2388
    • Thanassoulis, G.1    O'Donnell, C.J.2
  • 24
    • 0034672281 scopus 로고    scopus 로고
    • Lecithin cholesterol acyltransferase
    • COI: 1:CAS:528:DC%2BD3cXosFCgsbo%3D, PID: 11111093
    • Jonas A. Lecithin cholesterol acyltransferase. Biochim Biophys Acta. 2000;1529:245–56.
    • (2000) Biochim Biophys Acta , vol.1529 , pp. 245-256
    • Jonas, A.1
  • 25
    • 84864835923 scopus 로고    scopus 로고
    • Lecithin:cholesterol acyltransferase: old friend or foe in atherosclerosis?
    • COI: 1:CAS:528:DC%2BC38Xht1Ghs7bI, PID: 22566575
    • Kunnen S, Van Eck M. Lecithin:cholesterol acyltransferase: old friend or foe in atherosclerosis? J Lipid Res. 2012;53:1783–99.
    • (2012) J Lipid Res , vol.53 , pp. 1783-1799
    • Kunnen, S.1    Van Eck, M.2
  • 26
    • 0033920220 scopus 로고    scopus 로고
    • Overexpression of human lecithin:cholesterol acyltransferase in mice offers no protection against diet-induced atherosclerosis
    • COI: 1:CAS:528:DC%2BD3cXlvVaktrc%3D, PID: 10937770
    • Mehlum A, Gjernes E, Solberg LA, Hagve TA, Prydz H. Overexpression of human lecithin:cholesterol acyltransferase in mice offers no protection against diet-induced atherosclerosis. APMIS: acta pathologica, microbiologica, et immunologica Scandinavica. 2000;108:336–42.
    • (2000) APMIS: acta pathologica, microbiologica, et immunologica Scandinavica , vol.108 , pp. 336-342
    • Mehlum, A.1    Gjernes, E.2    Solberg, L.A.3    Hagve, T.A.4    Prydz, H.5
  • 27
    • 0344429365 scopus 로고    scopus 로고
    • High plasma HDL concentrations associated with enhanced atherosclerosis in transgenic mice overexpressing lecithin-cholesteryl acyltransferase
    • COI: 1:CAS:528:DyaK2sXkt1Kmsbk%3D, PID: 9212100
    • Berard AM, Foger B, Remaley A, et al. High plasma HDL concentrations associated with enhanced atherosclerosis in transgenic mice overexpressing lecithin-cholesteryl acyltransferase. Nat Med. 1997;3:744–9.
    • (1997) Nat Med , vol.3 , pp. 744-749
    • Berard, A.M.1    Foger, B.2    Remaley, A.3
  • 29
    • 67651085117 scopus 로고    scopus 로고
    • Lecithin: cholesterol acyltransferase expression has minimal effects on macrophage reverse cholesterol transport in vivo
    • COI: 1:CAS:528:DC%2BD1MXotV2qurk%3D, PID: 19564558
    • Tanigawa H, Billheimer JT, Tohyama J, et al. Lecithin: cholesterol acyltransferase expression has minimal effects on macrophage reverse cholesterol transport in vivo. Circulation. 2009;120:160–9.
    • (2009) Circulation , vol.120 , pp. 160-169
    • Tanigawa, H.1    Billheimer, J.T.2    Tohyama, J.3
  • 30
    • 0033973733 scopus 로고    scopus 로고
    • LCAT modulates atherogenic plasma lipoproteins and the extent of atherosclerosis only in the presence of normal LDL receptors in transgenic rabbits
    • COI: 1:CAS:528:DC%2BD3cXht1yqs7w%3D, PID: 10669643
    • Brousseau ME, Kauffman RD, Herderick EE, et al. LCAT modulates atherogenic plasma lipoproteins and the extent of atherosclerosis only in the presence of normal LDL receptors in transgenic rabbits. Arterioscler Thromb Vasc Biol. 2000;20(2):450–8.
    • (2000) Arterioscler Thromb Vasc Biol , vol.20 , Issue.2 , pp. 450-458
    • Brousseau, M.E.1    Kauffman, R.D.2    Herderick, E.E.3
  • 31
    • 0030049443 scopus 로고    scopus 로고
    • Lecithin:cholesterol acyltransferase overexpression generates hyperalpha-lipoproteinemia and a nonatherogenic lipoprotein pattern in transgenic rabbits
    • COI: 1:CAS:528:DyaK28XhtlSmtLY%3D, PID: 8626790
    • Hoeg JM, Vaisman BL, Demosky SJ Jr, et al. Lecithin:cholesterol acyltransferase overexpression generates hyperalpha-lipoproteinemia and a nonatherogenic lipoprotein pattern in transgenic rabbits. J Biol Chem. 1996;271:4396–402.
    • (1996) J Biol Chem , vol.271 , pp. 4396-4402
    • Hoeg, J.M.1    Vaisman, B.L.2    Demosky, S.J.3
  • 32
    • 62349085494 scopus 로고    scopus 로고
    • Adenoviral expression of human lecithin-cholesterol acyltransferase in nonhuman primates leads to an antiatherogenic lipoprotein phenotype by increasing high-density lipoprotein and lowering low-density lipoprotein
    • COI: 1:CAS:528:DC%2BD1MXjsFWkurY%3D, PID: 19303980
    • Amar MJ, Shamburek RD, Vaisman B, et al. Adenoviral expression of human lecithin-cholesterol acyltransferase in nonhuman primates leads to an antiatherogenic lipoprotein phenotype by increasing high-density lipoprotein and lowering low-density lipoprotein. Metab Clin Exp. 2009;58:568–75.
    • (2009) Metab Clin Exp , vol.58 , pp. 568-575
    • Amar, M.J.1    Shamburek, R.D.2    Vaisman, B.3
  • 33
    • 0035805531 scopus 로고    scopus 로고
    • Analysis of glomerulosclerosis and atherosclerosis in lecithin cholesterol acyltransferase-deficient mice
    • COI: 1:CAS:528:DC%2BD3MXjs1Orsb4%3D, PID: 11278414
    • Lambert G, Sakai N, Vaisman BL, et al. Analysis of glomerulosclerosis and atherosclerosis in lecithin cholesterol acyltransferase-deficient mice. J Biol Chem. 2001;276:15090–8.
    • (2001) J Biol Chem , vol.276 , pp. 15090-15098
    • Lambert, G.1    Sakai, N.2    Vaisman, B.L.3
  • 34
    • 0036479142 scopus 로고    scopus 로고
    • Lecithin:cholesterol acyltransferase deficiency increases atherosclerosis in the low density lipoprotein receptor and apolipoprotein E knockout mice
    • COI: 1:CAS:528:DC%2BD38XhtVakt7k%3D, PID: 11719520
    • Furbee JW Jr, Sawyer JK, Parks JS. Lecithin:cholesterol acyltransferase deficiency increases atherosclerosis in the low density lipoprotein receptor and apolipoprotein E knockout mice. J Biol Chem. 2002;277:3511–9.
    • (2002) J Biol Chem , vol.277 , pp. 3511-3519
    • Furbee, J.W.1    Sawyer, J.K.2    Parks, J.S.3
  • 35
    • 0037023773 scopus 로고    scopus 로고
    • Oxidative stress is markedly elevated in lecithin:cholesterol acyltransferase-deficient mice and is paradoxically reversed in the apolipoprotein E knockout background in association with a reduction in atherosclerosis
    • COI: 1:CAS:528:DC%2BD38XivVeksrc%3D, PID: 11809774
    • Ng DS, Maguire GF, Wylie J, et al. Oxidative stress is markedly elevated in lecithin:cholesterol acyltransferase-deficient mice and is paradoxically reversed in the apolipoprotein E knockout background in association with a reduction in atherosclerosis. J Biol Chem. 2002;277:11715–20.
    • (2002) J Biol Chem , vol.277 , pp. 11715-11720
    • Ng, D.S.1    Maguire, G.F.2    Wylie, J.3
  • 36
    • 0242286640 scopus 로고    scopus 로고
    • Dose-dependent acceleration of high-density lipoprotein catabolism by endothelial lipase
    • COI: 1:CAS:528:DC%2BD3sXot1Cgs78%3D, PID: 14517167
    • Maugeais C, Tietge UJ, Broedl UC, et al. Dose-dependent acceleration of high-density lipoprotein catabolism by endothelial lipase. Circulation. 2003;108:2121–6.
    • (2003) Circulation , vol.108 , pp. 2121-2126
    • Maugeais, C.1    Tietge, U.J.2    Broedl, U.C.3
  • 37
    • 0032901331 scopus 로고    scopus 로고
    • A novel endothelial-derived lipase that modulates HDL metabolism
    • COI: 1:CAS:528:DyaK1MXitFKrsLo%3D, PID: 10192396
    • Jaye M, Lynch KJ, Krawiec J, et al. A novel endothelial-derived lipase that modulates HDL metabolism. Nat Genet. 1999;21:424–8.
    • (1999) Nat Genet , vol.21 , pp. 424-428
    • Jaye, M.1    Lynch, K.J.2    Krawiec, J.3
  • 38
    • 0037314398 scopus 로고    scopus 로고
    • Endothelial lipase is a major determinant of HDL level
    • COI: 1:CAS:528:DC%2BD3sXpvFSnsQ%3D%3D, PID: 12569160
    • Ishida T, Choi S, Kundu RK, et al. Endothelial lipase is a major determinant of HDL level. J Clin Invest. 2003;111:347–55.
    • (2003) J Clin Invest , vol.111 , pp. 347-355
    • Ishida, T.1    Choi, S.2    Kundu, R.K.3
  • 39
    • 3042702876 scopus 로고    scopus 로고
    • Endothelial lipase promotes the catabolism of ApoB-containing lipoproteins
    • COI: 1:CAS:528:DC%2BD2cXlvVSgtLk%3D, PID: 15117821
    • Broedl UC, Maugeais C, Millar JS, et al. Endothelial lipase promotes the catabolism of ApoB-containing lipoproteins. Circ Res. 2004;94:1554–61.
    • (2004) Circ Res , vol.94 , pp. 1554-1561
    • Broedl, U.C.1    Maugeais, C.2    Millar, J.S.3
  • 40
    • 69449092915 scopus 로고    scopus 로고
    • Hepatic SR-BI, not endothelial lipase, expression determines biliary cholesterol secretion in mice
    • COI: 1:CAS:528:DC%2BD1MXovV2murc%3D, PID: 19252221
    • Wiersma H, Gatti A, Nijstad N, Kuipers F, Tietge UJ. Hepatic SR-BI, not endothelial lipase, expression determines biliary cholesterol secretion in mice. J Lipid Res. 2009;50:1571–80.
    • (2009) J Lipid Res , vol.50 , pp. 1571-1580
    • Wiersma, H.1    Gatti, A.2    Nijstad, N.3    Kuipers, F.4    Tietge, U.J.5
  • 41
    • 85019684398 scopus 로고    scopus 로고
    • Increased hepatic expression of endothelial lipase inhibits cholesterol diet-induced hypercholesterolemia and atherosclerosis in transgenic rabbits, Arterioscler Thromb Vasc Biol
    • Wang C, Nishijima K, Kitajima S, et al. Increased hepatic expression of endothelial lipase inhibits cholesterol diet-induced hypercholesterolemia and atherosclerosis in transgenic rabbits. Arterioscler Thromb Vasc Biol. 2017;
    • (2017) Kitajima S, et al
    • Wang, C.1    Nishijima, K.2
  • 42
    • 65249186429 scopus 로고    scopus 로고
    • Loss-of-function variants in endothelial lipase are a cause of elevated HDL cholesterol in humans
    • COI: 1:CAS:528:DC%2BD1MXktlSntLg%3D, PID: 19287092
    • Edmondson AC, Brown RJ, Kathiresan S, et al. Loss-of-function variants in endothelial lipase are a cause of elevated HDL cholesterol in humans. J Clin Invest. 2009;119:1042–50.
    • (2009) J Clin Invest , vol.119 , pp. 1042-1050
    • Edmondson, A.C.1    Brown, R.J.2    Kathiresan, S.3
  • 43
    • 77956628427 scopus 로고    scopus 로고
    • Impact of combined deficiency of hepatic lipase and endothelial lipase on the metabolism of both high-density lipoproteins and apolipoprotein B-containing lipoproteins
    • COI: 1:CAS:528:DC%2BC3cXpvVSgu7g%3D, PID: 20558822
    • Brown RJ, Lagor WR, Sankaranaravanan S, et al. Impact of combined deficiency of hepatic lipase and endothelial lipase on the metabolism of both high-density lipoproteins and apolipoprotein B-containing lipoproteins. Circ Res. 2010;107:357–64.
    • (2010) Circ Res , vol.107 , pp. 357-364
    • Brown, R.J.1    Lagor, W.R.2    Sankaranaravanan, S.3
  • 44
    • 30844437283 scopus 로고    scopus 로고
    • Endothelial lipase modulates HDL but has no effect on atherosclerosis development in apoE-/- and LDLR-/- mice
    • COI: 1:CAS:528:DC%2BD2MXhtlWmsLbF, PID: 16199802
    • Ko KW, Paul A, Ma K, Li L, Chan L. Endothelial lipase modulates HDL but has no effect on atherosclerosis development in apoE-/- and LDLR-/- mice. J Lipid Res. 2005;46:2586–94.
    • (2005) J Lipid Res , vol.46 , pp. 2586-2594
    • Ko, K.W.1    Paul, A.2    Ma, K.3    Li, L.4    Chan, L.5
  • 45
    • 7244229703 scopus 로고    scopus 로고
    • Endothelial lipase modulates susceptibility to atherosclerosis in apolipoprotein-E-deficient mice
    • COI: 1:CAS:528:DC%2BD2cXosFylsrs%3D, PID: 15304490
    • Ishida T, Choi SY, Kundu RK, et al. Endothelial lipase modulates susceptibility to atherosclerosis in apolipoprotein-E-deficient mice. J Biol Chem. 2004;279:45085–92.
    • (2004) J Biol Chem , vol.279 , pp. 45085-45092
    • Ishida, T.1    Choi, S.Y.2    Kundu, R.K.3
  • 46
    • 0344406740 scopus 로고    scopus 로고
    • Endothelial lipase is a major genetic determinant for high-density lipoprotein concentration, structure, and metabolism
    • COI: 1:CAS:528:DC%2BD3sXitVait7s%3D, PID: 12601178
    • Ma K, Cilingiroglu M, Otvos JD, Ballantyne CM, Marian AJ, Chan L. Endothelial lipase is a major genetic determinant for high-density lipoprotein concentration, structure, and metabolism. Proc Natl Acad Sci U S A. 2003;100:2748–53.
    • (2003) Proc Natl Acad Sci U S A , vol.100 , pp. 2748-2753
    • Ma, K.1    Cilingiroglu, M.2    Otvos, J.D.3    Ballantyne, C.M.4    Marian, A.J.5    Chan, L.6
  • 47
    • 26444435788 scopus 로고    scopus 로고
    • Hepatic expression of scavenger receptor class B type I (SR-BI) is a positive regulator of macrophage reverse cholesterol transport in vivo
    • COI: 1:CAS:528:DC%2BD2MXhtVygt7bL, PID: 16200214
    • Zhang Y, Da Silva JR, Reilly M, Billheimer JT, Rothblat GH, Rader DJ. Hepatic expression of scavenger receptor class B type I (SR-BI) is a positive regulator of macrophage reverse cholesterol transport in vivo. J Clin Invest. 2005;115:2870–4.
    • (2005) J Clin Invest , vol.115 , pp. 2870-2874
    • Zhang, Y.1    Da Silva, J.R.2    Reilly, M.3    Billheimer, J.T.4    Rothblat, G.H.5    Rader, D.J.6
  • 48
    • 0032484117 scopus 로고    scopus 로고
    • Liver-specific overexpression of scavenger receptor BI decreases levels of very low density lipoprotein ApoB, low density lipoprotein ApoB, and high density lipoprotein in transgenic mice
    • COI: 1:CAS:528:DyaK1cXnvFOmsrg%3D, PID: 9830042
    • Wang N, Arai T, Ji Y, Rinninger F, Tall AR. Liver-specific overexpression of scavenger receptor BI decreases levels of very low density lipoprotein ApoB, low density lipoprotein ApoB, and high density lipoprotein in transgenic mice. J Biol Chem. 1998;273:32920–6.
    • (1998) J Biol Chem , vol.273 , pp. 32920-32926
    • Wang, N.1    Arai, T.2    Ji, Y.3    Rinninger, F.4    Tall, A.R.5
  • 49
    • 0033548442 scopus 로고    scopus 로고
    • Lower plasma levels and accelerated clearance of high density lipoprotein (HDL) and non-HDL cholesterol in scavenger receptor class B type I transgenic mice
    • COI: 1:CAS:528:DyaK1MXhvFWqsLw%3D, PID: 10066776
    • Ueda Y, Royer L, Gong E, et al. Lower plasma levels and accelerated clearance of high density lipoprotein (HDL) and non-HDL cholesterol in scavenger receptor class B type I transgenic mice. J Biol Chem. 1999;274:7165–71.
    • (1999) J Biol Chem , vol.274 , pp. 7165-7171
    • Ueda, Y.1    Royer, L.2    Gong, E.3
  • 50
    • 0030960169 scopus 로고    scopus 로고
    • Overexpression of the HDL receptor SR-BI alters plasma HDL and bile cholesterol levels
    • COI: 1:CAS:528:DyaK2sXjsVensL4%3D, PID: 9163428
    • Kozarsky KF, Donahee MH, Rigotti A, Iqbal SN, Edelman ER, Krieger M. Overexpression of the HDL receptor SR-BI alters plasma HDL and bile cholesterol levels. Nature. 1997;387:414–7.
    • (1997) Nature , vol.387 , pp. 414-417
    • Kozarsky, K.F.1    Donahee, M.H.2    Rigotti, A.3    Iqbal, S.N.4    Edelman, E.R.5    Krieger, M.6
  • 51
    • 0034060299 scopus 로고    scopus 로고
    • Gene transfer and hepatic overexpression of the HDL receptor SR-BI reduces atherosclerosis in the cholesterol-fed LDL receptor-deficient mouse
    • COI: 1:CAS:528:DC%2BD3cXit1alu7g%3D, PID: 10712397
    • Kozarsky KF, Donahee MH, Glick JM, Krieger M, Rader DJ. Gene transfer and hepatic overexpression of the HDL receptor SR-BI reduces atherosclerosis in the cholesterol-fed LDL receptor-deficient mouse. Arterioscler Thromb Vasc Biol. 2000;20:721–7.
    • (2000) Arterioscler Thromb Vasc Biol , vol.20 , pp. 721-727
    • Kozarsky, K.F.1    Donahee, M.H.2    Glick, J.M.3    Krieger, M.4    Rader, D.J.5
  • 52
    • 0033593222 scopus 로고    scopus 로고
    • Decreased atherosclerosis in heterozygous low density lipoprotein receptor-deficient mice expressing the scavenger receptor BI transgene
    • COI: 1:CAS:528:DyaK1MXovVGkug%3D%3D, PID: 9891004
    • Arai T, Wang N, Bezouevski M, Welch C, Tall AR. Decreased atherosclerosis in heterozygous low density lipoprotein receptor-deficient mice expressing the scavenger receptor BI transgene. J Biol Chem. 1999;274:2366–71.
    • (1999) J Biol Chem , vol.274 , pp. 2366-2371
    • Arai, T.1    Wang, N.2    Bezouevski, M.3    Welch, C.4    Tall, A.R.5
  • 53
    • 13144275202 scopus 로고    scopus 로고
    • Targeted mutation reveals a central role for SR-BI in hepatic selective uptake of high density lipoprotein cholesterol
    • COI: 1:CAS:528:DyaK1cXis1Ogsb8%3D, PID: 9539787
    • Varban ML, Rinninger F, Wang N, et al. Targeted mutation reveals a central role for SR-BI in hepatic selective uptake of high density lipoprotein cholesterol. Proc Natl Acad Sci U S A. 1998;95:4619–24.
    • (1998) Proc Natl Acad Sci U S A , vol.95 , pp. 4619-4624
    • Varban, M.L.1    Rinninger, F.2    Wang, N.3
  • 54
    • 0030729724 scopus 로고    scopus 로고
    • A targeted mutation in the murine gene encoding the high density lipoprotein (HDL) receptor scavenger receptor class B type I reveals its key role in HDL metabolism
    • COI: 1:CAS:528:DyaK2sXns1yltL0%3D, PID: 9356497
    • Rigotti A, Trigatti BL, Penman M, Rayburn H, Herz J, Krieger M. A targeted mutation in the murine gene encoding the high density lipoprotein (HDL) receptor scavenger receptor class B type I reveals its key role in HDL metabolism. Proc Natl Acad Sci U S A. 1997;94:12610–5.
    • (1997) Proc Natl Acad Sci U S A , vol.94 , pp. 12610-12615
    • Rigotti, A.1    Trigatti, B.L.2    Penman, M.3    Rayburn, H.4    Herz, J.5    Krieger, M.6
  • 55
    • 11144247737 scopus 로고    scopus 로고
    • Scavenger receptor class B type I mediates the selective uptake of high-density lipoprotein-associated cholesteryl ester by the liver in mice
    • COI: 1:CAS:528:DC%2BD2cXhtFaiu7jI, PID: 15528479
    • Brundert M, Ewert A, Heeren J, et al. Scavenger receptor class B type I mediates the selective uptake of high-density lipoprotein-associated cholesteryl ester by the liver in mice. Arterioscler Thromb Vasc Biol. 2005;25:143–8.
    • (2005) Arterioscler Thromb Vasc Biol , vol.25 , pp. 143-148
    • Brundert, M.1    Ewert, A.2    Heeren, J.3
  • 56
    • 0034032488 scopus 로고    scopus 로고
    • Increased LDL cholesterol and atherosclerosis in LDL receptor-deficient mice with attenuated expression of scavenger receptor B1
    • COI: 1:CAS:528:DC%2BD3cXjtV2hsL0%3D, PID: 10764675
    • Huszar D, Varban ML, Rinninger F, et al. Increased LDL cholesterol and atherosclerosis in LDL receptor-deficient mice with attenuated expression of scavenger receptor B1. Arterioscler Thromb Vasc Biol. 2000;20:1068–73.
    • (2000) Arterioscler Thromb Vasc Biol , vol.20 , pp. 1068-1073
    • Huszar, D.1    Varban, M.L.2    Rinninger, F.3
  • 57
    • 0037155049 scopus 로고    scopus 로고
    • Loss of SR-BI expression leads to the early onset of occlusive atherosclerotic coronary artery disease, spontaneous myocardial infarctions, severe cardiac dysfunction, and premature death in apolipoprotein E-deficient mice
    • COI: 1:CAS:528:DC%2BD38Xhs1Wrt78%3D, PID: 11861414
    • Braun A, Trigatti BL, Post MJ, et al. Loss of SR-BI expression leads to the early onset of occlusive atherosclerotic coronary artery disease, spontaneous myocardial infarctions, severe cardiac dysfunction, and premature death in apolipoprotein E-deficient mice. Circ Res. 2002;90:270–6.
    • (2002) Circ Res , vol.90 , pp. 270-276
    • Braun, A.1    Trigatti, B.L.2    Post, M.J.3
  • 58
    • 0027325516 scopus 로고
    • Severe atherosclerosis in transgenic mice expressing simian cholesteryl ester transfer protein
    • COI: 1:CAS:528:DyaK3sXltFClt7c%3D, PID: 8316302
    • Marotti KR, Castle CK, Boyle TP, Lin AH, Murray RW, Melchior GW. Severe atherosclerosis in transgenic mice expressing simian cholesteryl ester transfer protein. Nature. 1993;364:73–5.
    • (1993) Nature , vol.364 , pp. 73-75
    • Marotti, K.R.1    Castle, C.K.2    Boyle, T.P.3    Lin, A.H.4    Murray, R.W.5    Melchior, G.W.6
  • 59
    • 0032917975 scopus 로고    scopus 로고
    • Increased atherosclerosis in ApoE and LDL receptor gene knock-out mice as a result of human cholesteryl ester transfer protein transgene expression
    • COI: 1:CAS:528:DyaK1MXislaqsrg%3D, PID: 10195942
    • Plump AS, Masucci-Magoulas L, Bruce C, Bisgaier CL, Breslow JL, Tall AR. Increased atherosclerosis in ApoE and LDL receptor gene knock-out mice as a result of human cholesteryl ester transfer protein transgene expression. Arterioscler Thromb Vasc Biol. 1999;19:1105–10.
    • (1999) Arterioscler Thromb Vasc Biol , vol.19 , pp. 1105-1110
    • Plump, A.S.1    Masucci-Magoulas, L.2    Bruce, C.3    Bisgaier, C.L.4    Breslow, J.L.5    Tall, A.R.6
  • 60
    • 0028784246 scopus 로고
    • Decreased early atherosclerotic lesions in hypertriglyceridemic mice expressing cholesteryl ester transfer protein transgene
    • COI: 1:CAS:528:DyaK2MXosFyhtLc%3D, PID: 7560101
    • Hayek T, Masucci-Magoulas L, Jiang X, et al. Decreased early atherosclerotic lesions in hypertriglyceridemic mice expressing cholesteryl ester transfer protein transgene. J Clin Invest. 1995;96:2071–4.
    • (1995) J Clin Invest , vol.96 , pp. 2071-2074
    • Hayek, T.1    Masucci-Magoulas, L.2    Jiang, X.3
  • 61
    • 34247214080 scopus 로고    scopus 로고
    • Cholesteryl ester transfer protein (CETP) expression protects against diet induced atherosclerosis in SR-BI deficient mice
    • COI: 1:CAS:528:DC%2BD2sXislCrsL8%3D, PID: 17272756
    • Harder C, Lau P, Meng A, Whitman SC, McPherson R. Cholesteryl ester transfer protein (CETP) expression protects against diet induced atherosclerosis in SR-BI deficient mice. Arterioscler Thromb Vasc Biol. 2007;27:858–64.
    • (2007) Arterioscler Thromb Vasc Biol , vol.27 , pp. 858-864
    • Harder, C.1    Lau, P.2    Meng, A.3    Whitman, S.C.4    McPherson, R.5
  • 62
    • 34948860018 scopus 로고    scopus 로고
    • Expression of cholesteryl ester transfer protein in mice promotes macrophage reverse cholesterol transport
    • COI: 1:CAS:528:DC%2BD2sXpvFWksbg%3D, PID: 17709636
    • Tanigawa H, Billheimer JT, Tohyama J, Zhang Y, Rothblat G, Rader DJ. Expression of cholesteryl ester transfer protein in mice promotes macrophage reverse cholesterol transport. Circulation. 2007;116:1267–73.
    • (2007) Circulation , vol.116 , pp. 1267-1273
    • Tanigawa, H.1    Billheimer, J.T.2    Tohyama, J.3    Zhang, Y.4    Rothblat, G.5    Rader, D.J.6
  • 63
    • 0034644214 scopus 로고    scopus 로고
    • A cholesteryl ester transfer protein inhibitor attenuates atherosclerosis in rabbits
    • COI: 1:CAS:528:DC%2BD3cXlsVWgtrY%3D, PID: 10910363
    • Okamoto H, Yonemori F, Wakitani K, Minowa T, Maeda K, Shinkai H. A cholesteryl ester transfer protein inhibitor attenuates atherosclerosis in rabbits. Nature. 2000;406:203–7.
    • (2000) Nature , vol.406 , pp. 203-207
    • Okamoto, H.1    Yonemori, F.2    Wakitani, K.3    Minowa, T.4    Maeda, K.5    Shinkai, H.6
  • 64
    • 0033822810 scopus 로고    scopus 로고
    • Vaccine-induced antibodies inhibit CETP activity in vivo and reduce aortic lesions in a rabbit model of atherosclerosis
    • COI: 1:CAS:528:DC%2BD3cXntV2itL8%3D, PID: 10978256
    • Rittershaus CW, Miller DP, Thomas LJ, et al. Vaccine-induced antibodies inhibit CETP activity in vivo and reduce aortic lesions in a rabbit model of atherosclerosis. Arterioscler Thromb Vasc Biol. 2000;20:2106–12.
    • (2000) Arterioscler Thromb Vasc Biol , vol.20 , pp. 2106-2112
    • Rittershaus, C.W.1    Miller, D.P.2    Thomas, L.J.3
  • 65
    • 0036907139 scopus 로고    scopus 로고
    • Cholesteryl ester transfer protein inhibitor (JTT-705) and the development of atherosclerosis in rabbits with severe hypercholesterolaemia
    • COI: 1:CAS:528:DC%2BD38XovF2jurg%3D
    • Huang Z, Inazu A, Nohara A, Higashikata T, Mabuchi H. Cholesteryl ester transfer protein inhibitor (JTT-705) and the development of atherosclerosis in rabbits with severe hypercholesterolaemia. Clinical Science (London, England: 1979). 2002;103:587–94.
    • (2002) Clinical Science (London, England: 1979) , vol.103 , pp. 587-594
    • Huang, Z.1    Inazu, A.2    Nohara, A.3    Higashikata, T.4    Mabuchi, H.5
  • 66
    • 0032570684 scopus 로고    scopus 로고
    • Effect of antisense oligonucleotides against cholesteryl ester transfer protein on the development of atherosclerosis in cholesterol-fed rabbits
    • COI: 1:CAS:528:DyaK1cXhs1CgtLw%3D, PID: 9478952
    • Sugano M, Makino N, Sawada S, et al. Effect of antisense oligonucleotides against cholesteryl ester transfer protein on the development of atherosclerosis in cholesterol-fed rabbits. J Biol Chem. 1998;273:5033–6.
    • (1998) J Biol Chem , vol.273 , pp. 5033-5036
    • Sugano, M.1    Makino, N.2    Sawada, S.3
  • 67
    • 85018844030 scopus 로고    scopus 로고
    • Deficiency of cholesteryl ester transfer protein protects against atherosclerosis in rabbits
    • COI: 1:CAS:528:DC%2BC2sXotlOrsrc%3D, PID: 28428219
    • Zhang J, Niimi M, Yang D, et al. Deficiency of cholesteryl ester transfer protein protects against atherosclerosis in rabbits. Arterioscler Thromb Vasc Biol. 2017;37:1068–75.
    • (2017) Arterioscler Thromb Vasc Biol , vol.37 , pp. 1068-1075
    • Zhang, J.1    Niimi, M.2    Yang, D.3
  • 68
    • 84887099827 scopus 로고    scopus 로고
    • Discovery and refinement of loci associated with lipid levels
    • COI: 1:CAS:528:DC%2BC3sXhsFOitb7O, PID: 24097068
    • Willer CJ, Schmidt EM, Sengupta S, et al. Discovery and refinement of loci associated with lipid levels. Nat Genet. 2013;45:1274–83.
    • (2013) Nat Genet , vol.45 , pp. 1274-1283
    • Willer, C.J.1    Schmidt, E.M.2    Sengupta, S.3
  • 69
    • 77955505564 scopus 로고    scopus 로고
    • Biological, clinical and population relevance of 95 loci for blood lipids
    • COI: 1:CAS:528:DC%2BC3cXhtVSmurfI, PID: 20686565
    • Teslovich TM, Musunuru K, Smith AV, et al. Biological, clinical and population relevance of 95 loci for blood lipids. Nature. 2010;466:707–13.
    • (2010) Nature , vol.466 , pp. 707-713
    • Teslovich, T.M.1    Musunuru, K.2    Smith, A.V.3
  • 70
    • 85021756461 scopus 로고    scopus 로고
    • Fifteen new risk loci for coronary artery disease highlight arterial-wall-specific mechanisms
    • Howson JMM, Zhao W, Barnes DR, et al. Fifteen new risk loci for coronary artery disease highlight arterial-wall-specific mechanisms. Nat Genet. 2017;
    • (2017) Nat Genet
    • Howson, J.M.M.1    Zhao, W.2    Barnes, D.R.3
  • 71
    • 85013005062 scopus 로고    scopus 로고
    • Systematic evaluation of pleiotropy identifies 6 further loci associated with coronary artery disease
    • COI: 1:CAS:528:DC%2BC2sXis1yltrc%3D, PID: 28209224
    • Webb TR, Erdmann J, Stirrups KE, et al. Systematic evaluation of pleiotropy identifies 6 further loci associated with coronary artery disease. J Am Coll Cardiol. 2017;69:823–36.
    • (2017) J Am Coll Cardiol , vol.69 , pp. 823-836
    • Webb, T.R.1    Erdmann, J.2    Stirrups, K.E.3
  • 72
    • 7244250124 scopus 로고    scopus 로고
    • Lipid-related genes and myocardial infarction in 4685 cases and 3460 controls: discrepancies between genotype, blood lipid concentrations, and coronary disease risk
    • PID: 15256516
    • Keavney B, Palmer A, Parish S, et al. Lipid-related genes and myocardial infarction in 4685 cases and 3460 controls: discrepancies between genotype, blood lipid concentrations, and coronary disease risk. Int J Epidemiol. 2004;33:1002–13.
    • (2004) Int J Epidemiol , vol.33 , pp. 1002-1013
    • Keavney, B.1    Palmer, A.2    Parish, S.3
  • 73
    • 84924606733 scopus 로고    scopus 로고
    • Circulating cholesteryl ester transfer protein and coronary heart disease: mendelian randomization meta-analysis
    • COI: 1:CAS:528:DC%2BC2MXjtFarurY%3D, PID: 25561046
    • Niu W, Qi Y. Circulating cholesteryl ester transfer protein and coronary heart disease: mendelian randomization meta-analysis. Circ Cardiovasc Genet. 2015;8:114–21.
    • (2015) Circ Cardiovasc Genet , vol.8 , pp. 114-121
    • Niu, W.1    Qi, Y.2
  • 74
    • 84856786437 scopus 로고    scopus 로고
    • LCAT, HDL cholesterol and ischemic cardiovascular disease: a Mendelian randomization study of HDL cholesterol in 54,500 individuals
    • COI: 1:CAS:528:DC%2BC38XisFOns70%3D, PID: 22090275
    • Haase CL, Tybjaerg-Hansen A, Qayyum AA, Schou J, Nordestgaard BG, Frikke-Schmidt R. LCAT, HDL cholesterol and ischemic cardiovascular disease: a Mendelian randomization study of HDL cholesterol in 54,500 individuals. J Clin Endocrinol Metab. 2012;97:E248–56.
    • (2012) J Clin Endocrinol Metab , vol.97 , pp. E248-E256
    • Haase, C.L.1    Tybjaerg-Hansen, A.2    Qayyum, A.A.3    Schou, J.4    Nordestgaard, B.G.5    Frikke-Schmidt, R.6
  • 75
    • 85020786942 scopus 로고    scopus 로고
    • A, Won HH, Khera AV, Circ Res, This paper showed for the first time that loss-of-function coding mutations in CETP that raise HDL-C are associated with reduced risk of coronary heart disease
    • • Nomura A, Won HH, Khera AV, et al. Protein truncating variants at the cholesteryl ester transfer protein gene and risk for coronary heart disease. Circ Res. 2017; This paper showed for the first time that loss-of-function coding mutations in CETP that raise HDL-C are associated with reduced risk of coronary heart disease
    • (2017) Protein truncating variants at the cholesteryl ester transfer protein gene and risk for coronary heart disease
    • Nomura, A.1
  • 76
    • 84964313174 scopus 로고    scopus 로고
    • Association of cholesteryl ester transfer protein (CETP) gene polymorphism, high density lipoprotein cholesterol and risk of coronary artery disease: a meta-analysis using a Mendelian randomization approach
    • PID: 25366166
    • Wu Z, Lou Y, Qiu X, et al. Association of cholesteryl ester transfer protein (CETP) gene polymorphism, high density lipoprotein cholesterol and risk of coronary artery disease: a meta-analysis using a Mendelian randomization approach. BMC Medical Genetics. 2014;15:118.
    • (2014) BMC Medical Genetics , vol.15 , pp. 118
    • Wu, Z.1    Lou, Y.2    Qiu, X.3
  • 77
    • 69549103151 scopus 로고    scopus 로고
    • Functional lecithin: cholesterol acyltransferase is not required for efficient atheroprotection in humans
    • COI: 1:CAS:528:DC%2BD1MXpsFylu74%3D, PID: 19687369
    • Calabresi L, Baldassarre D, Castelnuovo S, et al. Functional lecithin: cholesterol acyltransferase is not required for efficient atheroprotection in humans. Circulation. 2009;120:628–35.
    • (2009) Circulation , vol.120 , pp. 628-635
    • Calabresi, L.1    Baldassarre, D.2    Castelnuovo, S.3
  • 78
    • 24144480542 scopus 로고    scopus 로고
    • The molecular basis of lecithin:cholesterol acyltransferase deficiency syndromes: a comprehensive study of molecular and biochemical findings in 13 unrelated Italian families
    • COI: 1:CAS:528:DC%2BD2MXos1ekur8%3D, PID: 15994445
    • Calabresi L, Pisciotta L, Costantin A, et al. The molecular basis of lecithin:cholesterol acyltransferase deficiency syndromes: a comprehensive study of molecular and biochemical findings in 13 unrelated Italian families. Arterioscler Thromb Vasc Biol. 2005;25:1972–8.
    • (2005) Arterioscler Thromb Vasc Biol , vol.25 , pp. 1972-1978
    • Calabresi, L.1    Pisciotta, L.2    Costantin, A.3
  • 79
    • 8644289370 scopus 로고    scopus 로고
    • Lecithin: cholesterol acyltransferase (LCAT) deficiency and risk of vascular disease: 25 year follow-up
    • COI: 1:CAS:528:DC%2BD2cXpsFeqsbo%3D, PID: 15530911
    • Ayyobi AF, McGladdery SH, Chan S, John Mancini GB, Hill JS, Frohlich JJ. Lecithin: cholesterol acyltransferase (LCAT) deficiency and risk of vascular disease: 25 year follow-up. Atherosclerosis. 2004;177:361–6.
    • (2004) Atherosclerosis , vol.177 , pp. 361-366
    • Ayyobi, A.F.1    McGladdery, S.H.2    Chan, S.3    John Mancini, G.B.4    Hill, J.S.5    Frohlich, J.J.6
  • 80
    • 67349250436 scopus 로고    scopus 로고
    • Functional LCAT is not required for macrophage cholesterol efflux to human serum
    • COI: 1:CAS:528:DC%2BD1MXlsVKgt7c%3D, PID: 18922527
    • Calabresi L, Favari E, Moleri E, et al. Functional LCAT is not required for macrophage cholesterol efflux to human serum. Atherosclerosis. 2009;204:141–6.
    • (2009) Atherosclerosis , vol.204 , pp. 141-146
    • Calabresi, L.1    Favari, E.2    Moleri, E.3
  • 81
    • 23844493144 scopus 로고    scopus 로고
    • Compromised LCAT function is associated with increased atherosclerosis
    • COI: 1:CAS:528:DC%2BD2MXmvVKrur8%3D, PID: 16061733
    • Hovingh GK, Hutten BA, Holleboom AG, et al. Compromised LCAT function is associated with increased atherosclerosis. Circulation. 2005;112:879–84.
    • (2005) Circulation , vol.112 , pp. 879-884
    • Hovingh, G.K.1    Hutten, B.A.2    Holleboom, A.G.3
  • 82
    • 82455194933 scopus 로고    scopus 로고
    • Carriers of lecithin cholesterol acyltransferase gene mutations have accelerated atherogenesis as assessed by carotid 3.0-T magnetic resonance imaging [corrected]
    • COI: 1:CAS:528:DC%2BC38XhtlOnsro%3D, PID: 22133847
    • Duivenvoorden R, Holleboom AG, van den Bogaard B, et al. Carriers of lecithin cholesterol acyltransferase gene mutations have accelerated atherogenesis as assessed by carotid 3.0-T magnetic resonance imaging [corrected]. J Am Coll Cardiol. 2011;58:2481–7.
    • (2011) J Am Coll Cardiol , vol.58 , pp. 2481-2487
    • Duivenvoorden, R.1    Holleboom, A.G.2    van den Bogaard, B.3
  • 83
    • 16944362351 scopus 로고    scopus 로고
    • Genetic cholesteryl ester transfer protein deficiency is extremely frequent in the Omagari area of Japan. Marked hyperalphalipoproteinemia caused by CETP gene mutation is not associated with longevity
    • COI: 1:STN:280:DyaK2szjvVWqsQ%3D%3D, PID: 9194754
    • Hirano K, Yamashita S, Nakajima N, et al. Genetic cholesteryl ester transfer protein deficiency is extremely frequent in the Omagari area of Japan. Marked hyperalphalipoproteinemia caused by CETP gene mutation is not associated with longevity. Arterioscler Thromb Vasc Biol. 1997;17:1053–9.
    • (1997) Arterioscler Thromb Vasc Biol , vol.17 , pp. 1053-1059
    • Hirano, K.1    Yamashita, S.2    Nakajima, N.3
  • 84
    • 84964315855 scopus 로고    scopus 로고
    • Cholesteryl Ester Transfer Protein (CETP) Deficiency and CETP Inhibitors
    • PID: 25410905
    • Mabuchi H, Nohara A, Inazu A. Cholesteryl Ester Transfer Protein (CETP) Deficiency and CETP Inhibitors. Mol Cells. 2014;37(11):777–84.
    • (2014) Mol Cells , vol.37 , Issue.11 , pp. 777-784
    • Mabuchi, H.1    Nohara, A.2    Inazu, A.3
  • 85
    • 77949498424 scopus 로고    scopus 로고
    • Plasma levels of lecithin:cholesterol acyltransferase and risk of future coronary artery disease in apparently healthy men and women: a prospective case-control analysis nested in the EPIC-Norfolk population study
    • COI: 1:CAS:528:DC%2BC3cXptVWmsg%3D%3D, PID: 19671930
    • Holleboom AG, Kuivenhoven JA, Vergeer M, et al. Plasma levels of lecithin:cholesterol acyltransferase and risk of future coronary artery disease in apparently healthy men and women: a prospective case-control analysis nested in the EPIC-Norfolk population study. J Lipid Res. 2010;51:416–21.
    • (2010) J Lipid Res , vol.51 , pp. 416-421
    • Holleboom, A.G.1    Kuivenhoven, J.A.2    Vergeer, M.3
  • 86
    • 84893756641 scopus 로고    scopus 로고
    • Association of low-frequency and rare coding-sequence variants with blood lipids and coronary heart disease in 56,000 whites and blacks
    • COI: 1:CAS:528:DC%2BC2cXitVyksbs%3D, PID: 24507774
    • Peloso GM, Auer PL, Bis JC, et al. Association of low-frequency and rare coding-sequence variants with blood lipids and coronary heart disease in 56,000 whites and blacks. Am J Hum Genet. 2014;94:223–32.
    • (2014) Am J Hum Genet , vol.94 , pp. 223-232
    • Peloso, G.M.1    Auer, P.L.2    Bis, J.C.3
  • 87
    • 84879110156 scopus 로고
    • Increased risk of coronary artery disease in Caucasians with extremely low HDL cholesterol due to mutations in ABCA1, APOA1, and LCAT
    • Tietjen I, Hovingh GK, Singaraja R, et al. Increased risk of coronary artery disease in Caucasians with extremely low HDL cholesterol due to mutations in ABCA1, APOA1, and LCAT. Biochim Biophys Acta. 1821;2012:416–24.
    • (1821) Biochim Biophys Acta , vol.2012 , pp. 416-424
    • Tietjen, I.1    Hovingh, G.K.2    Singaraja, R.3
  • 88
    • 34247395573 scopus 로고    scopus 로고
    • Genetic etiology of isolated low HDL syndrome: incidence and heterogeneity of efflux defects
    • COI: 1:CAS:528:DC%2BD2sXktFagt7s%3D, PID: 17303779
    • Kiss RS, Kavaslar N, Okuhira K, et al. Genetic etiology of isolated low HDL syndrome: incidence and heterogeneity of efflux defects. Arterioscler Thromb Vasc Biol. 2007;27:1139–45.
    • (2007) Arterioscler Thromb Vasc Biol , vol.27 , pp. 1139-1145
    • Kiss, R.S.1    Kavaslar, N.2    Okuhira, K.3
  • 89
    • 0030933460 scopus 로고    scopus 로고
    • The molecular pathology of lecithin:cholesterol acyltransferase (LCAT) deficiency syndromes
    • COI: 1:CAS:528:DyaK2sXitFemsbo%3D, PID: 9162740
    • Kuivenhoven JA, Pritchard H, Hill J, Frohlich J, Assmann G, Kastelein J. The molecular pathology of lecithin:cholesterol acyltransferase (LCAT) deficiency syndromes. J Lipid Res. 1997;38:191–205.
    • (1997) J Lipid Res , vol.38 , pp. 191-205
    • Kuivenhoven, J.A.1    Pritchard, H.2    Hill, J.3    Frohlich, J.4    Assmann, G.5    Kastelein, J.6
  • 90
    • 84869497153 scopus 로고    scopus 로고
    • Patients with low HDL-cholesterol caused by mutations in LCAT have increased arterial stiffness
    • PID: 23078883
    • van den Bogaard B, Holleboom AG, Duivenvoorden R, et al. Patients with low HDL-cholesterol caused by mutations in LCAT have increased arterial stiffness. Atherosclerosis. 2012;225:481–5.
    • (2012) Atherosclerosis , vol.225 , pp. 481-485
    • van den Bogaard, B.1    Holleboom, A.G.2    Duivenvoorden, R.3
  • 91
    • 80054712848 scopus 로고    scopus 로고
    • High prevalence of mutations in LCAT in patients with low HDL cholesterol levels in The Netherlands: identification and characterization of eight novel mutations
    • COI: 1:CAS:528:DC%2BC3MXhtlagurvI, PID: 21901787
    • Holleboom AG, Kuivenhoven JA, Peelman F, et al. High prevalence of mutations in LCAT in patients with low HDL cholesterol levels in The Netherlands: identification and characterization of eight novel mutations. Hum Mutat. 2011;32:1290–8.
    • (2011) Hum Mutat , vol.32 , pp. 1290-1298
    • Holleboom, A.G.1    Kuivenhoven, J.A.2    Peelman, F.3
  • 92
    • 78349287329 scopus 로고    scopus 로고
    • Update on the role of endothelial lipase in high-density lipoprotein metabolism, reverse cholesterol transport, and atherosclerosis
    • COI: 1:CAS:528:DC%2BC3cXhsFKntLvP
    • Yasuda T, Ishida T, Rader DJ. Update on the role of endothelial lipase in high-density lipoprotein metabolism, reverse cholesterol transport, and atherosclerosis. Circulation journal: official journal of the Japanese Circulation Society. 2010;74:2263–70.
    • (2010) Circulation journal: official journal of the Japanese Circulation Society , vol.74 , pp. 2263-2270
    • Yasuda, T.1    Ishida, T.2    Rader, D.J.3
  • 93
    • 0037907677 scopus 로고    scopus 로고
    • Fatty acids liberated from high-density lipoprotein phospholipids by endothelial-derived lipase are incorporated into lipids in HepG2 cells
    • COI: 1:CAS:528:DC%2BD3sXjtFKls7Y%3D, PID: 12553881
    • Strauss JG, Hayn M, Zechner R, Levak-Frank S, Frank S. Fatty acids liberated from high-density lipoprotein phospholipids by endothelial-derived lipase are incorporated into lipids in HepG2 cells. The Biochemical Journal. 2003;371:981–8.
    • (2003) The Biochemical Journal , vol.371 , pp. 981-988
    • Strauss, J.G.1    Hayn, M.2    Zechner, R.3    Levak-Frank, S.4    Frank, S.5
  • 94
    • 27244458482 scopus 로고    scopus 로고
    • Evidence that endothelial lipase remodels high density lipoproteins without mediating the dissociation of apolipoprotein A-I
    • COI: 1:CAS:528:DC%2BD2MXktFaqtbw%3D, PID: 15687350
    • Jahangiri A, Rader DJ, Marchadier D, Curtiss LK, Bonnet DJ, Rye KA. Evidence that endothelial lipase remodels high density lipoproteins without mediating the dissociation of apolipoprotein A-I. J Lipid Res. 2005;46:896–903.
    • (2005) J Lipid Res , vol.46 , pp. 896-903
    • Jahangiri, A.1    Rader, D.J.2    Marchadier, D.3    Curtiss, L.K.4    Bonnet, D.J.5    Rye, K.A.6
  • 95
    • 0035988350 scopus 로고    scopus 로고
    • Characterization of the lipolytic activity of endothelial lipase
    • COI: 1:CAS:528:DC%2BD38XksFWgsro%3D, PID: 12032167
    • McCoy MG, Sun GS, Marchadier D, Maugeais C, Glick JM, Rader DJ. Characterization of the lipolytic activity of endothelial lipase. J Lipid Res. 2002;43:921–9.
    • (2002) J Lipid Res , vol.43 , pp. 921-929
    • McCoy, M.G.1    Sun, G.S.2    Marchadier, D.3    Maugeais, C.4    Glick, J.M.5    Rader, D.J.6
  • 96
    • 0037056085 scopus 로고    scopus 로고
    • Identification of genetic variants in endothelial lipase in persons with elevated high-density lipoprotein cholesterol
    • COI: 1:CAS:528:DC%2BD38XntVKks7k%3D, PID: 12221047
    • deLemos AS, Wolfe ML, Long CJ, Sivapackianathan R, Rader DJ. Identification of genetic variants in endothelial lipase in persons with elevated high-density lipoprotein cholesterol. Circulation. 2002;106:1321–6.
    • (2002) Circulation , vol.106 , pp. 1321-1326
    • deLemos, A.S.1    Wolfe, M.L.2    Long, C.J.3    Sivapackianathan, R.4    Rader, D.J.5
  • 97
    • 84905057638 scopus 로고    scopus 로고
    • Identification of four novel genes contributing to familial elevated plasma HDL cholesterol in humans
    • COI: 1:CAS:528:DC%2BC2cXht1agsrnO, PID: 24891332
    • Singaraja RR, Tietjen I, Hovingh GK, et al. Identification of four novel genes contributing to familial elevated plasma HDL cholesterol in humans. J Lipid Res. 2014;55:1693–701.
    • (2014) J Lipid Res , vol.55 , pp. 1693-1701
    • Singaraja, R.R.1    Tietjen, I.2    Hovingh, G.K.3
  • 98
    • 84878041582 scopus 로고    scopus 로고
    • The impact of partial and complete loss-of-function mutations in endothelial lipase on high-density lipoprotein levels and functionality in humans
    • COI: 1:CAS:528:DC%2BC3sXlt1Wrtrk%3D, PID: 23243195
    • Singaraja RR, Sivapalaratnam S, Hovingh K, et al. The impact of partial and complete loss-of-function mutations in endothelial lipase on high-density lipoprotein levels and functionality in humans. Circ Cardiovasc Genet. 2013;6:54–62.
    • (2013) Circ Cardiovasc Genet , vol.6 , pp. 54-62
    • Singaraja, R.R.1    Sivapalaratnam, S.2    Hovingh, K.3
  • 99
    • 84865406477 scopus 로고    scopus 로고
    • Segregation of LIPG, CETP, and GALNT2 mutations in Caucasian families with extremely high HDL cholesterol
    • COI: 1:CAS:528:DC%2BC38Xht1Olt7bM, PID: 22952570
    • Tietjen I, Hovingh GK, Singaraja RR, et al. Segregation of LIPG, CETP, and GALNT2 mutations in Caucasian families with extremely high HDL cholesterol. PLoS One. 2012;7:e37437.
    • (2012) PLoS One , vol.7
    • Tietjen, I.1    Hovingh, G.K.2    Singaraja, R.R.3
  • 100
    • 84855290539 scopus 로고    scopus 로고
    • Mining the LIPG allelic spectrum reveals the contribution of rare and common regulatory variants to HDL cholesterol
    • COI: 1:CAS:528:DC%2BC3MXhs1OhtL%2FI, PID: 22174694
    • Khetarpal SA, Edmondson AC, Raghavan A, et al. Mining the LIPG allelic spectrum reveals the contribution of rare and common regulatory variants to HDL cholesterol. PLoS Genet. 2011;7:e1002393.
    • (2011) PLoS Genet , vol.7
    • Khetarpal, S.A.1    Edmondson, A.C.2    Raghavan, A.3
  • 101
    • 0242290832 scopus 로고    scopus 로고
    • The T111I mutation in the EL gene modulates the impact of dietary fat on the HDL profile in women
    • COI: 1:CAS:528:DC%2BD3sXos1Giurc%3D, PID: 12867537
    • Paradis ME, Couture P, Bosse Y, et al. The T111I mutation in the EL gene modulates the impact of dietary fat on the HDL profile in women. J Lipid Res. 2003;44:1902–8.
    • (2003) J Lipid Res , vol.44 , pp. 1902-1908
    • Paradis, M.E.1    Couture, P.2    Bosse, Y.3
  • 102
    • 67650092295 scopus 로고    scopus 로고
    • The T111I variant in the endothelial lipase gene and risk of coronary heart disease in three independent populations
    • COI: 1:CAS:528:DC%2BD1MXosVant7o%3D, PID: 19411665
    • Jensen MK, Rimm EB, Mukamal KJ, et al. The T111I variant in the endothelial lipase gene and risk of coronary heart disease in three independent populations. Eur Heart J. 2009;30:1584–9.
    • (2009) Eur Heart J , vol.30 , pp. 1584-1589
    • Jensen, M.K.1    Rimm, E.B.2    Mukamal, K.J.3
  • 103
    • 70349428501 scopus 로고    scopus 로고
    • Physical inactivity interacts with an endothelial lipase polymorphism to modulate high density lipoprotein cholesterol in the GOLDN study
    • COI: 1:CAS:528:DC%2BD1MXht1aju7nP, PID: 19380136
    • Smith CE, Arnett DK, Tsai MY, et al. Physical inactivity interacts with an endothelial lipase polymorphism to modulate high density lipoprotein cholesterol in the GOLDN study. Atherosclerosis. 2009;206:500–4.
    • (2009) Atherosclerosis , vol.206 , pp. 500-504
    • Smith, C.E.1    Arnett, D.K.2    Tsai, M.Y.3
  • 104
    • 84875427637 scopus 로고    scopus 로고
    • Population-based resequencing of LIPG and ZNF202 genes in subjects with extreme HDL levels
    • PID: 22723803
    • Razzaghi H, Santorico SA, Kamboh MI. Population-based resequencing of LIPG and ZNF202 genes in subjects with extreme HDL levels. Front Genet. 2012;3:89.
    • (2012) Front Genet , vol.3 , pp. 89
    • Razzaghi, H.1    Santorico, S.A.2    Kamboh, M.I.3
  • 105
    • 77955281827 scopus 로고    scopus 로고
    • Lack of association between common genetic variation in endothelial lipase (LIPG) and the risk for CAD and DVT
    • COI: 1:CAS:528:DC%2BC3cXps1Cls7g%3D, PID: 20466371
    • Vergeer M, Cohn DM, Boekholdt SM, et al. Lack of association between common genetic variation in endothelial lipase (LIPG) and the risk for CAD and DVT. Atherosclerosis. 2010;211:558–64.
    • (2010) Atherosclerosis , vol.211 , pp. 558-564
    • Vergeer, M.1    Cohn, D.M.2    Boekholdt, S.M.3
  • 106
    • 58149163149 scopus 로고    scopus 로고
    • Common variants at 30 loci contribute to polygenic dyslipidemia
    • COI: 1:CAS:528:DC%2BD1cXhsVKlt7vN, PID: 19060906
    • Kathiresan S, Willer CJ, Peloso GM, et al. Common variants at 30 loci contribute to polygenic dyslipidemia. Nat Genet. 2009;41:56–65.
    • (2009) Nat Genet , vol.41 , pp. 56-65
    • Kathiresan, S.1    Willer, C.J.2    Peloso, G.M.3
  • 107
    • 84942987885 scopus 로고    scopus 로고
    • A comprehensive 1,000 genomes-based genome-wide association meta-analysis of coronary artery disease
    • COI: 1:CAS:528:DC%2BC2MXhsV2lt7zO, PID: 26343387
    • Nikpay M, Goel A, Won HH, et al. A comprehensive 1,000 genomes-based genome-wide association meta-analysis of coronary artery disease. Nat Genet. 2015;47:1121–30.
    • (2015) Nat Genet , vol.47 , pp. 1121-1130
    • Nikpay, M.1    Goel, A.2    Won, H.H.3
  • 108
    • 84871969762 scopus 로고    scopus 로고
    • Large-scale association analysis identifies new risk loci for coronary artery disease
    • COI: 1:CAS:528:DC%2BC38XhslGkurrF, PID: 23202125
    • Deloukas P, Kanoni S, Willenborg C, et al. Large-scale association analysis identifies new risk loci for coronary artery disease. Nat Genet. 2013;45:25–33.
    • (2013) Nat Genet , vol.45 , pp. 25-33
    • Deloukas, P.1    Kanoni, S.2    Willenborg, C.3
  • 109
    • 84965036429 scopus 로고    scopus 로고
    • Variants with large effects on blood lipids and the role of cholesterol and triglycerides in coronary disease
    • COI: 1:CAS:528:DC%2BC28XntVCmurk%3D, PID: 27135400
    • Helgadottir A, Gretarsdottir S, Thorleifsson G, et al. Variants with large effects on blood lipids and the role of cholesterol and triglycerides in coronary disease. Nat Genet. 2016;48:634–9.
    • (2016) Nat Genet , vol.48 , pp. 634-639
    • Helgadottir, A.1    Gretarsdottir, S.2    Thorleifsson, G.3
  • 110
    • 0030046797 scopus 로고    scopus 로고
    • Identification of scavenger receptor SR-BI as a high density lipoprotein receptor
    • COI: 1:CAS:528:DyaK28XmvFyruw%3D%3D
    • Acton S, Rigotti A, Landschulz KT, Xu S, Hobbs HH, Krieger M. Identification of scavenger receptor SR-BI as a high density lipoprotein receptor. Science (New York, NY). 1996;271:518–20.
    • (1996) Science (New York, NY) , vol.271 , pp. 518-520
    • Acton, S.1    Rigotti, A.2    Landschulz, K.T.3    Xu, S.4    Hobbs, H.H.5    Krieger, M.6
  • 111
    • 85011300275 scopus 로고    scopus 로고
    • SR-BI as target in atherosclerosis and cardiovascular disease–a comprehensive appraisal of the cellular functions of SR-BI in physiology and disease
    • COI: 1:CAS:528:DC%2BC2sXit1Slsbg%3D, PID: 28162236
    • Hoekstra M. SR-BI as target in atherosclerosis and cardiovascular disease–a comprehensive appraisal of the cellular functions of SR-BI in physiology and disease. Atherosclerosis. 2017;258:153–61.
    • (2017) Atherosclerosis , vol.258 , pp. 153-161
    • Hoekstra, M.1
  • 112
    • 0033585115 scopus 로고    scopus 로고
    • Hepatic scavenger receptor BI promotes rapid clearance of high density lipoprotein free cholesterol and its transport into bile
    • COI: 1:CAS:528:DyaK1MXns1aqu7g%3D, PID: 10559220
    • Ji Y, Wang N, Ramakrishnan R, et al. Hepatic scavenger receptor BI promotes rapid clearance of high density lipoprotein free cholesterol and its transport into bile. J Biol Chem. 1999;274:33398–402.
    • (1999) J Biol Chem , vol.274 , pp. 33398-33402
    • Ji, Y.1    Wang, N.2    Ramakrishnan, R.3
  • 113
    • 0034617069 scopus 로고    scopus 로고
    • Relationship between expression levels and atherogenesis in scavenger receptor class B, type I transgenics
    • COI: 1:CAS:528:DC%2BD3cXkvVyiu7g%3D, PID: 10751392
    • Ueda Y, Gong E, Royer L, Cooper PN, Francone OL, Rubin EM. Relationship between expression levels and atherogenesis in scavenger receptor class B, type I transgenics. J Biol Chem. 2000;275:20368–73.
    • (2000) J Biol Chem , vol.275 , pp. 20368-20373
    • Ueda, Y.1    Gong, E.2    Royer, L.3    Cooper, P.N.4    Francone, O.L.5    Rubin, E.M.6
  • 114
    • 0037931116 scopus 로고    scopus 로고
    • Differential effects of scavenger receptor BI deficiency on lipid metabolism in cells of the arterial wall and in the liver
    • PID: 12639961
    • Van Eck M, Twisk J, Hoekstra M, et al. Differential effects of scavenger receptor BI deficiency on lipid metabolism in cells of the arterial wall and in the liver. J Biol Chem. 2003;278:23699–705.
    • (2003) J Biol Chem , vol.278 , pp. 23699-23705
    • Van Eck, M.1    Twisk, J.2    Hoekstra, M.3
  • 115
    • 13044272898 scopus 로고    scopus 로고
    • Influence of the high density lipoprotein receptor SR-BI on reproductive and cardiovascular pathophysiology
    • COI: 1:CAS:528:DyaK1MXltVCjsr0%3D, PID: 10430941
    • Trigatti B, Rayburn H, Vinals M, et al. Influence of the high density lipoprotein receptor SR-BI on reproductive and cardiovascular pathophysiology. Proc Natl Acad Sci U S A. 1999;96:9322–7.
    • (1999) Proc Natl Acad Sci U S A , vol.96 , pp. 9322-9327
    • Trigatti, B.1    Rayburn, H.2    Vinals, M.3
  • 116
    • 0033032512 scopus 로고    scopus 로고
    • Association of polymorphisms at the SR-BI gene locus with plasma lipid levels and body mass index in a white population
    • COI: 1:CAS:528:DyaK1MXkvV2ksr8%3D, PID: 10397692
    • Acton S, Osgood D, Donoghue M, et al. Association of polymorphisms at the SR-BI gene locus with plasma lipid levels and body mass index in a white population. Arterioscler Thromb Vasc Biol. 1999;19:1734–43.
    • (1999) Arterioscler Thromb Vasc Biol , vol.19 , pp. 1734-1743
    • Acton, S.1    Osgood, D.2    Donoghue, M.3
  • 117
    • 0038578149 scopus 로고    scopus 로고
    • Genetic variation at the scavenger receptor class B type I gene locus determines plasma lipoprotein concentrations and particle size and interacts with type 2 diabetes: the framingham study
    • COI: 1:CAS:528:DC%2BD3sXkslCrsbc%3D, PID: 12788901
    • Osgood D, Corella D, Demissie S, et al. Genetic variation at the scavenger receptor class B type I gene locus determines plasma lipoprotein concentrations and particle size and interacts with type 2 diabetes: the framingham study. J Clin Endocrinol Metab. 2003;88:2869–79.
    • (2003) J Clin Endocrinol Metab , vol.88 , pp. 2869-2879
    • Osgood, D.1    Corella, D.2    Demissie, S.3
  • 118
    • 2942511946 scopus 로고    scopus 로고
    • Population-based study of SR-BI genetic variation and lipid profile
    • COI: 1:CAS:528:DC%2BD2cXkslWlsbY%3D, PID: 15186961
    • Morabia A, Ross BM, Costanza MC, et al. Population-based study of SR-BI genetic variation and lipid profile. Atherosclerosis. 2004;175:159–68.
    • (2004) Atherosclerosis , vol.175 , pp. 159-168
    • Morabia, A.1    Ross, B.M.2    Costanza, M.C.3
  • 119
    • 84925842756 scopus 로고    scopus 로고
    • Impact of genetic variants in human scavenger receptor class B type I (SCARB1) on plasma lipid traits
    • COI: 1:CAS:528:DC%2BC2cXitFaltrnE, PID: 25245032
    • Niemsiri V, Wang X, Pirim D, et al. Impact of genetic variants in human scavenger receptor class B type I (SCARB1) on plasma lipid traits. Circ Cardiovasc Genet. 2014;7:838–47.
    • (2014) Circ Cardiovasc Genet , vol.7 , pp. 838-847
    • Niemsiri, V.1    Wang, X.2    Pirim, D.3
  • 120
    • 84864282845 scopus 로고    scopus 로고
    • Association of SCARB1 variants with subclinical atherosclerosis and incident cardiovascular disease: the multi-ethnic study of atherosclerosis
    • COI: 1:CAS:528:DC%2BC38XhtVCrsbrL, PID: 22628436
    • Manichaikul A, Naj AC, Herrington D, Post W, Rich SS, Rodriguez A. Association of SCARB1 variants with subclinical atherosclerosis and incident cardiovascular disease: the multi-ethnic study of atherosclerosis. Arterioscler Thromb Vasc Biol. 2012;32:1991–9.
    • (2012) Arterioscler Thromb Vasc Biol , vol.32 , pp. 1991-1999
    • Manichaikul, A.1    Naj, A.C.2    Herrington, D.3    Post, W.4    Rich, S.S.5    Rodriguez, A.6
  • 121
    • 34447097282 scopus 로고    scopus 로고
    • Scavenger receptor class B type I polymorphisms and peripheral arterial disease
    • COI: 1:CAS:528:DC%2BD2sXnsFKqur0%3D, PID: 17618962
    • Ritsch A, Sonderegger G, Sandhofer A, et al. Scavenger receptor class B type I polymorphisms and peripheral arterial disease. Metab Clin Exp. 2007;56:1135–41.
    • (2007) Metab Clin Exp , vol.56 , pp. 1135-1141
    • Ritsch, A.1    Sonderegger, G.2    Sandhofer, A.3
  • 122
    • 77952500072 scopus 로고    scopus 로고
    • Association of scavenger receptor class B type I polymorphisms with subclinical atherosclerosis: the multi-ethnic study of atherosclerosis
    • COI: 1:CAS:528:DC%2BC3cXjslSgsb0%3D, PID: 20160195
    • Naj AC, West M, Rich SS, et al. Association of scavenger receptor class B type I polymorphisms with subclinical atherosclerosis: the multi-ethnic study of atherosclerosis. Circ Cardiovasc Genet. 2010;3:47–52.
    • (2010) Circ Cardiovasc Genet , vol.3 , pp. 47-52
    • Naj, A.C.1    West, M.2    Rich, S.S.3
  • 123
    • 84930673107 scopus 로고    scopus 로고
    • Association of the lipoprotein receptor SCARB1 common missense variant rs4238001 with incident coronary heart disease
    • PID: 25993026
    • Manichaikul A, Wang XQ, Musani SK, et al. Association of the lipoprotein receptor SCARB1 common missense variant rs4238001 with incident coronary heart disease. PLoS One. 2015;10:e0125497.
    • (2015) PLoS One , vol.10
    • Manichaikul, A.1    Wang, X.Q.2    Musani, S.K.3
  • 124
    • 78651352098 scopus 로고    scopus 로고
    • Genetic variant of the scavenger receptor BI in humans
    • COI: 1:CAS:528:DC%2BC3MXmvFarsQ%3D%3D, PID: 21226579
    • Vergeer M, Korporaal SJ, Franssen R, et al. Genetic variant of the scavenger receptor BI in humans. N Engl J Med. 2011;364:136–45.
    • (2011) N Engl J Med , vol.364 , pp. 136-145
    • Vergeer, M.1    Korporaal, S.J.2    Franssen, R.3
  • 125
    • 84887058576 scopus 로고    scopus 로고
    • Common variants associated with plasma triglycerides and risk for coronary artery disease
    • COI: 1:CAS:528:DC%2BC3sXhsFOiur%2FN, PID: 24097064
    • Do R, Willer CJ, Schmidt EM, et al. Common variants associated with plasma triglycerides and risk for coronary artery disease. Nat Genet. 2013;45:1345–52.
    • (2013) Nat Genet , vol.45 , pp. 1345-1352
    • Do, R.1    Willer, C.J.2    Schmidt, E.M.3
  • 126
    • 84951334880 scopus 로고    scopus 로고
    • Exome-wide association analysis reveals novel coding sequence variants associated with lipid traits in Chinese
    • COI: 1:CAS:528:DC%2BC2MXitVygu7zJ, PID: 26690388
    • Tang CS, Zhang H, Cheung CY, et al. Exome-wide association analysis reveals novel coding sequence variants associated with lipid traits in Chinese. Nat Commun. 2015;6:10206.
    • (2015) Nat Commun , vol.6 , pp. 10206
    • Tang, C.S.1    Zhang, H.2    Cheung, C.Y.3
  • 127
    • 45349105911 scopus 로고    scopus 로고
    • Association of cholesteryl ester transfer protein genotypes with CETP mass and activity, lipid levels, and coronary risk
    • COI: 1:CAS:528:DC%2BD1cXns1Sktb4%3D, PID: 18560005
    • Thompson A, Di Angelantonio E, Sarwar N, et al. Association of cholesteryl ester transfer protein genotypes with CETP mass and activity, lipid levels, and coronary risk. JAMA. 2008;299:2777–88.
    • (2008) JAMA , vol.299 , pp. 2777-2788
    • Thompson, A.1    Di Angelantonio, E.2    Sarwar, N.3
  • 128
    • 0034750404 scopus 로고    scopus 로고
    • The -629C>A polymorphism in the CETP gene does not explain the association of TaqIB polymorphism with risk and age of myocardial infarction in Icelandic men
    • COI: 1:CAS:528:DC%2BD3MXnvFCrur8%3D, PID: 11689220
    • Eiriksdottir G, Bolla MK, Thorsson B, Sigurdsson G, Humphries SE, Gudnason V. The -629C>A polymorphism in the CETP gene does not explain the association of TaqIB polymorphism with risk and age of myocardial infarction in Icelandic men. Atherosclerosis. 2001;159:187–92.
    • (2001) Atherosclerosis , vol.159 , pp. 187-192
    • Eiriksdottir, G.1    Bolla, M.K.2    Thorsson, B.3    Sigurdsson, G.4    Humphries, S.E.5    Gudnason, V.6
  • 129
    • 84872898064 scopus 로고    scopus 로고
    • Common variation in cholesteryl ester transfer protein: relationship of first major adverse cardiovascular events with the apolipoprotein B/apolipoprotein A-I ratio and the total cholesterol/high-density lipoprotein cholesterol ratio
    • PID: 23351584
    • Kappelle PJ, Gansevoort RT, Hillege HJ, Wolffenbuttel BH, Dullaart RP. Common variation in cholesteryl ester transfer protein: relationship of first major adverse cardiovascular events with the apolipoprotein B/apolipoprotein A-I ratio and the total cholesterol/high-density lipoprotein cholesterol ratio. Journal of Clinical Lipidology. 2013;7:56–64.
    • (2013) Journal of Clinical Lipidology , vol.7 , pp. 56-64
    • Kappelle, P.J.1    Gansevoort, R.T.2    Hillege, H.J.3    Wolffenbuttel, B.H.4    Dullaart, R.P.5
  • 130
    • 0027515096 scopus 로고
    • Delayed catabolism of high density lipoprotein apolipoproteins A-I and A-II in human cholesteryl ester transfer protein deficiency
    • COI: 1:CAS:528:DyaK2cXivVOgtQ%3D%3D, PID: 8408618
    • Ikewaki K, Rader DJ, Sakamoto T, et al. Delayed catabolism of high density lipoprotein apolipoproteins A-I and A-II in human cholesteryl ester transfer protein deficiency. J Clin Invest. 1993;92:1650–8.
    • (1993) J Clin Invest , vol.92 , pp. 1650-1658
    • Ikewaki, K.1    Rader, D.J.2    Sakamoto, T.3
  • 131
    • 0025104275 scopus 로고
    • Increased high-density lipoprotein levels caused by a common cholesteryl-ester transfer protein gene mutation
    • COI: 1:STN:280:DyaK3M%2FhsFamtw%3D%3D, PID: 2215607
    • Inazu A, Brown ML, Hesler CB, et al. Increased high-density lipoprotein levels caused by a common cholesteryl-ester transfer protein gene mutation. N Engl J Med. 1990;323:1234–8.
    • (1990) N Engl J Med , vol.323 , pp. 1234-1238
    • Inazu, A.1    Brown, M.L.2    Hesler, C.B.3
  • 132
    • 0028135441 scopus 로고
    • Genetic cholesteryl ester transfer protein deficiency caused by two prevalent mutations as a major determinant of increased levels of high density lipoprotein cholesterol
    • COI: 1:CAS:528:DyaK2MXhvFKhurg%3D, PID: 7962532
    • Inazu A, Jiang XC, Haraki T, et al. Genetic cholesteryl ester transfer protein deficiency caused by two prevalent mutations as a major determinant of increased levels of high density lipoprotein cholesterol. J Clin Invest. 1994;94:1872–82.
    • (1994) J Clin Invest , vol.94 , pp. 1872-1882
    • Inazu, A.1    Jiang, X.C.2    Haraki, T.3
  • 133
    • 0022346576 scopus 로고
    • Deficiency of serum cholesteryl-ester transfer activity in patients with familial hyperalphalipoproteinaemia
    • COI: 1:STN:280:DyaL287jtVyntw%3D%3D, PID: 3937535
    • Koizumi J, Mabuchi H, Yoshimura A, et al. Deficiency of serum cholesteryl-ester transfer activity in patients with familial hyperalphalipoproteinaemia. Atherosclerosis. 1985;58:175–86.
    • (1985) Atherosclerosis , vol.58 , pp. 175-186
    • Koizumi, J.1    Mabuchi, H.2    Yoshimura, A.3
  • 135
    • 84978763806 scopus 로고    scopus 로고
    • TTC39B deficiency stabilizes LXR reducing both atherosclerosis and steatohepatitis
    • COI: 1:CAS:528:DC%2BC28XhtFahtrnI, PID: 27383786, This manuscript elucidated the functional genomics by which a novel GWAS locus for HDL-C at the gene TTC39B influences LXR, lipid metabolism, and atherosclerosis
    • • Hsieh J, Koseki M, Molusky MM, et al. TTC39B deficiency stabilizes LXR reducing both atherosclerosis and steatohepatitis. Nature. 2016;535:303–7. This manuscript elucidated the functional genomics by which a novel GWAS locus for HDL-C at the gene TTC39B influences LXR, lipid metabolism, and atherosclerosis
    • (2016) Nature , vol.535 , pp. 303-307
    • Hsieh, J.1    Koseki, M.2    Molusky, M.M.3
  • 136
    • 38649132270 scopus 로고    scopus 로고
    • Six new loci associated with blood low-density lipoprotein cholesterol, high-density lipoprotein cholesterol or triglycerides in humans
    • COI: 1:CAS:528:DC%2BD1cXhtl2qsL0%3D, PID: 18193044
    • Kathiresan S, Melander O, Guiducci C, et al. Six new loci associated with blood low-density lipoprotein cholesterol, high-density lipoprotein cholesterol or triglycerides in humans. Nat Genet. 2008;40:189–97.
    • (2008) Nat Genet , vol.40 , pp. 189-197
    • Kathiresan, S.1    Melander, O.2    Guiducci, C.3
  • 137
    • 82955239839 scopus 로고    scopus 로고
    • Heterozygosity for a loss-of-function mutation in GALNT2 improves plasma triglyceride clearance in man
    • COI: 1:CAS:528:DC%2BC3MXhs1SktrzN, PID: 22152306
    • Holleboom AG, Karlsson H, Lin RS, et al. Heterozygosity for a loss-of-function mutation in GALNT2 improves plasma triglyceride clearance in man. Cell Metab. 2011;14:811–8.
    • (2011) Cell Metab , vol.14 , pp. 811-818
    • Holleboom, A.G.1    Karlsson, H.2    Lin, R.S.3
  • 138
    • 84951777022 scopus 로고    scopus 로고
    • Multiple hepatic regulatory variants at the GALNT2 GWAS locus associated with high-density lipoprotein cholesterol
    • COI: 1:CAS:528:DC%2BC2MXhvVykurnL, PID: 26637976
    • Roman TS, Marvelle AF, Fogarty MP, et al. Multiple hepatic regulatory variants at the GALNT2 GWAS locus associated with high-density lipoprotein cholesterol. Am J Hum Genet. 2015;97:801–15.
    • (2015) Am J Hum Genet , vol.97 , pp. 801-815
    • Roman, T.S.1    Marvelle, A.F.2    Fogarty, M.P.3
  • 139
    • 84991044385 scopus 로고    scopus 로고
    • Loss of function of GALNT2 lowers high-density lipoproteins in humans, nonhuman primates, and rodents
    • COI: 1:CAS:528:DC%2BC28Xht1KlsrnF, PID: 27508872
    • Khetarpal SA, Schjoldager KT, Christoffersen C, et al. Loss of function of GALNT2 lowers high-density lipoproteins in humans, nonhuman primates, and rodents. Cell Metab. 2016;24:234–45.
    • (2016) Cell Metab , vol.24 , pp. 234-245
    • Khetarpal, S.A.1    Schjoldager, K.T.2    Christoffersen, C.3
  • 140
    • 79957607662 scopus 로고    scopus 로고
    • Identification of an imprinted master trans regulator at the KLF14 locus related to multiple metabolic phenotypes
    • COI: 1:CAS:528:DC%2BC3MXmtV2htLo%3D, PID: 21572415
    • Small KS, Hedman AK, Grundberg E, et al. Identification of an imprinted master trans regulator at the KLF14 locus related to multiple metabolic phenotypes. Nat Genet. 2011;43:561–4.
    • (2011) Nat Genet , vol.43 , pp. 561-564
    • Small, K.S.1    Hedman, A.K.2    Grundberg, E.3
  • 141
    • 77954143522 scopus 로고    scopus 로고
    • Twelve type 2 diabetes susceptibility loci identified through large-scale association analysis
    • COI: 1:CAS:528:DC%2BC3cXnvFykt70%3D, PID: 20581827
    • Voight BF, Scott LJ, Steinthorsdottir V, et al. Twelve type 2 diabetes susceptibility loci identified through large-scale association analysis. Nat Genet. 2010;42:579–89.
    • (2010) Nat Genet , vol.42 , pp. 579-589
    • Voight, B.F.1    Scott, L.J.2    Steinthorsdottir, V.3
  • 142
    • 72449122779 scopus 로고    scopus 로고
    • Parental origin of sequence variants associated with complex diseases
    • COI: 1:CAS:528:DC%2BD1MXhsFOhtbvJ, PID: 20016592
    • Kong A, Steinthorsdottir V, Masson G, et al. Parental origin of sequence variants associated with complex diseases. Nature. 2009;462:868–74.
    • (2009) Nature , vol.462 , pp. 868-874
    • Kong, A.1    Steinthorsdottir, V.2    Masson, G.3
  • 143
    • 84943222952 scopus 로고    scopus 로고
    • Perhexiline activates KLF14 and reduces atherosclerosis by modulating ApoA-I production
    • PID: 26368306
    • Guo Y, Fan Y, Zhang J, et al. Perhexiline activates KLF14 and reduces atherosclerosis by modulating ApoA-I production. J Clin Invest. 2015;125:3819–30.
    • (2015) J Clin Invest , vol.125 , pp. 3819-3830
    • Guo, Y.1    Fan, Y.2    Zhang, J.3
  • 144
    • 84983472699 scopus 로고    scopus 로고
    • Cardiometabolic risk loci share downstream cis- and trans-gene regulation across tissues and diseases
    • COI: 1:CAS:528:DC%2BC28XhtlCju7zE
    • Franzen O, Ermel R, Cohain A, et al. Cardiometabolic risk loci share downstream cis- and trans-gene regulation across tissues and diseases. Science (New York, NY). 2016;353:827–30.
    • (2016) Science (New York, NY) , vol.353 , pp. 827-830
    • Franzen, O.1    Ermel, R.2    Cohain, A.3
  • 145
    • 79957993750 scopus 로고    scopus 로고
    • Identification, replication, and functional fine-mapping of expression quantitative trait loci in primary human liver tissue
    • COI: 1:CAS:528:DC%2BC3MXntVWqu7k%3D, PID: 21637794
    • Innocenti F, Cooper GM, Stanaway IB, et al. Identification, replication, and functional fine-mapping of expression quantitative trait loci in primary human liver tissue. PLoS Genet. 2011;7:e1002078.
    • (2011) PLoS Genet , vol.7
    • Innocenti, F.1    Cooper, G.M.2    Stanaway, I.B.3
  • 146
    • 85014326417 scopus 로고    scopus 로고
    • Genetic regulation of adipose gene expression and cardio-metabolic traits
    • COI: 1:CAS:528:DC%2BC2sXjvVWrsLg%3D, PID: 28257690
    • Civelek M, Wu Y, Pan C, et al. Genetic regulation of adipose gene expression and cardio-metabolic traits. Am J Hum Genet. 2017;100:428–43.
    • (2017) Am J Hum Genet , vol.100 , pp. 428-443
    • Civelek, M.1    Wu, Y.2    Pan, C.3
  • 147
    • 2342441562 scopus 로고    scopus 로고
    • Lifestyle determinants of high-density lipoprotein cholesterol: the National Heart, Lung, and Blood Institute Family Heart Study
    • COI: 1:CAS:528:DC%2BD2cXhslensLg%3D, PID: 14999205
    • Ellison RC, Zhang Y, Qureshi MM, Knox S, Arnett DK, Province MA. Lifestyle determinants of high-density lipoprotein cholesterol: the National Heart, Lung, and Blood Institute Family Heart Study. Am Heart J. 2004;147:529–35.
    • (2004) Am Heart J , vol.147 , pp. 529-535
    • Ellison, R.C.1    Zhang, Y.2    Qureshi, M.M.3    Knox, S.4    Arnett, D.K.5    Province, M.A.6
  • 148
    • 84859731598 scopus 로고    scopus 로고
    • Raising HDL-C can be achieved by both lifestyle changes and pharmacological means
    • PID: 22272435
    • Barter P. Raising HDL-C can be achieved by both lifestyle changes and pharmacological means. Introduction Atherosclerosis Supplements. 2011;12:265–6.
    • (2011) Introduction Atherosclerosis Supplements , vol.12 , pp. 265-266
    • Barter, P.1
  • 149
    • 84868648516 scopus 로고    scopus 로고
    • The not-so-simple HDL story: is it time to revise the HDL cholesterol hypothesis?
    • COI: 1:CAS:528:DC%2BC38XhtlWnsrnK, PID: 22961164
    • Rader DJ, Tall AR. The not-so-simple HDL story: is it time to revise the HDL cholesterol hypothesis? Nat Med. 2012;18:1344–6.
    • (2012) Nat Med , vol.18 , pp. 1344-1346
    • Rader, D.J.1    Tall, A.R.2
  • 150
    • 78651379500 scopus 로고    scopus 로고
    • Cholesterol efflux capacity, high-density lipoprotein function, and atherosclerosis
    • COI: 1:CAS:528:DC%2BC3MXmvFarsA%3D%3D, PID: 21226578
    • Khera AV, Cuchel M, de la Llera-Moya M, et al. Cholesterol efflux capacity, high-density lipoprotein function, and atherosclerosis. N Engl J Med. 2011;364:127–35.
    • (2011) N Engl J Med , vol.364 , pp. 127-135
    • Khera, A.V.1    Cuchel, M.2    de la Llera-Moya, M.3
  • 151
    • 84919343998 scopus 로고    scopus 로고
    • HDL cholesterol efflux capacity and incident cardiovascular events
    • COI: 1:CAS:528:DC%2BC2MXhvVKhs7g%3D, PID: 25404125, This paper was the first to report an inverse association between HDL cholesterol efflux capacity and incident CV events and showed that this was independent of HDL-C
    • • Rohatgi A, Khera A, Berry JD, et al. HDL cholesterol efflux capacity and incident cardiovascular events. N Engl J Med. 2014;371:2383–93. This paper was the first to report an inverse association between HDL cholesterol efflux capacity and incident CV events and showed that this was independent of HDL-C.
    • (2014) N Engl J Med , vol.371 , pp. 2383-2393
    • Rohatgi, A.1    Khera, A.2    Berry, J.D.3
  • 152
    • 84934437744 scopus 로고    scopus 로고
    • Association of HDL cholesterol efflux capacity with incident coronary heart disease events: a prospective case-control study
    • COI: 1:CAS:528:DC%2BC2MXhsFSlt7zL
    • Saleheen D, Scott R, Javad S, et al. Association of HDL cholesterol efflux capacity with incident coronary heart disease events: a prospective case-control study. The Lancet Diabetes & Endocrinology. 2015;3:507–13.
    • (2015) The Lancet Diabetes & Endocrinology , vol.3 , pp. 507-513
    • Saleheen, D.1    Scott, R.2    Javad, S.3
  • 153
    • 84938239687 scopus 로고    scopus 로고
    • High-density lipoprotein cholesterol efflux capacity as a relevant predictor of atherosclerotic coronary disease
    • COI: 1:CAS:528:DC%2BC2MXhtFKrtrnM, PID: 26246268
    • Ishikawa T, Ayaori M, Uto-Kondo H, Nakajima T, Mutoh M, Ikewaki K. High-density lipoprotein cholesterol efflux capacity as a relevant predictor of atherosclerotic coronary disease. Atherosclerosis. 2015;242:318–22.
    • (2015) Atherosclerosis , vol.242 , pp. 318-322
    • Ishikawa, T.1    Ayaori, M.2    Uto-Kondo, H.3    Nakajima, T.4    Mutoh, M.5    Ikewaki, K.6
  • 154
    • 84879113852 scopus 로고    scopus 로고
    • Paradoxical association of enhanced cholesterol efflux with increased incident cardiovascular risks
    • COI: 1:CAS:528:DC%2BC3sXptlKru7c%3D, PID: 23520163
    • Li XM, Tang WH, Mosior MK, et al. Paradoxical association of enhanced cholesterol efflux with increased incident cardiovascular risks. Arterioscler Thromb Vasc Biol. 2013;33:1696–705.
    • (2013) Arterioscler Thromb Vasc Biol , vol.33 , pp. 1696-1705
    • Li, X.M.1    Tang, W.H.2    Mosior, M.K.3
  • 155
    • 84904252744 scopus 로고    scopus 로고
    • Effects of extended-release niacin with laropiprant in high-risk patients
    • PID: 25014686
    • Landray MJ, Haynes R, Hopewell JC, et al. Effects of extended-release niacin with laropiprant in high-risk patients. N Engl J Med. 2014;371:203–12.
    • (2014) N Engl J Med , vol.371 , pp. 203-212
    • Landray, M.J.1    Haynes, R.2    Hopewell, J.C.3
  • 156
    • 84955662453 scopus 로고    scopus 로고
    • Extended-Release niacin/laropiprant improves overall efficacy of postprandial reverse cholesterol transport
    • PID: 26681758
    • El Khoury P, Waldmann E, Huby T, et al. Extended-Release niacin/laropiprant improves overall efficacy of postprandial reverse cholesterol transport. Arterioscler Thromb Vasc Biol. 2016;36:285–94.
    • (2016) Arterioscler Thromb Vasc Biol , vol.36 , pp. 285-294
    • El Khoury, P.1    Waldmann, E.2    Huby, T.3
  • 157
    • 0034763557 scopus 로고    scopus 로고
    • Intravenous apoA-I/lecithin discs increase pre-beta-HDL concentration in tissue fluid and stimulate reverse cholesterol transport in humans
    • COI: 1:CAS:528:DC%2BD3MXotFGqu7o%3D, PID: 11590214
    • Nanjee MN, Cooke CJ, Garvin R, et al. Intravenous apoA-I/lecithin discs increase pre-beta-HDL concentration in tissue fluid and stimulate reverse cholesterol transport in humans. J Lipid Res. 2001;42:1586–93.
    • (2001) J Lipid Res , vol.42 , pp. 1586-1593
    • Nanjee, M.N.1    Cooke, C.J.2    Garvin, R.3
  • 158
    • 58149153296 scopus 로고    scopus 로고
    • Infusion of reconstituted high-density lipoprotein leads to acute changes in human atherosclerotic plaque
    • COI: 1:CAS:528:DC%2BD1cXhtlaqs7fO, PID: 18832751
    • Shaw JA, Bobik A, Murphy A, et al. Infusion of reconstituted high-density lipoprotein leads to acute changes in human atherosclerotic plaque. Circ Res. 2008;103:1084–91.
    • (2008) Circ Res , vol.103 , pp. 1084-1091
    • Shaw, J.A.1    Bobik, A.2    Murphy, A.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.