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Volumn 36, Issue 2, 2016, Pages 285-294

Extended-Release Niacin/Laropiprant Improves Overall Efficacy of Postprandial Reverse Cholesterol Transport

Author keywords

CETP; cholesterol efflux; HDL CE uptake; in vivo metabolic studies; macrophage

Indexed keywords

APOLIPOPROTEIN B; CHOLESTEROL ESTER TRANSFER PROTEIN; HIGH DENSITY LIPOPROTEIN; HIGH DENSITY LIPOPROTEIN CHOLESTEROL; LAROPIPRANT PLUS NICOTINIC ACID; LOW DENSITY LIPOPROTEIN CHOLESTEROL; SCAVENGER RECEPTOR BI; TRIACYLGLYCEROL; APOB PROTEIN, HUMAN; APOLIPOPROTEIN B100; CHOLESTEROL; DRUG COMBINATION; HYPOCHOLESTEROLEMIC AGENT; INDOLE DERIVATIVE; MK-0524; NICOTINIC ACID;

EID: 84955662453     PISSN: 10795642     EISSN: 15244636     Source Type: Journal    
DOI: 10.1161/ATVBAHA.115.306834     Document Type: Article
Times cited : (21)

References (44)
  • 1
    • 84893651437 scopus 로고    scopus 로고
    • Heart disease and stroke statistics-2014 update: A report from the American Heart Association
    • Go AS, Mozaffarian D, Roger VL, American Heart Association Statistics Committee and Stroke Statistics Subcommittee Heart disease and stroke statistics-2014 update: a report from the American Heart Association. Circulation 2014 129 e28 e292. doi: 10.1161/01.cir.0000441139.02102.80.
    • (2014) Circulation , vol.129 , pp. e28-e292
    • Go, A.S.1    Mozaffarian, D.2    Roger, V.L.3
  • 2
    • 11844296800 scopus 로고    scopus 로고
    • Efficacy and safety of high-density lipoprotein cholesterol-increasing compounds: A meta-analysis of randomized controlled trials
    • Birjmohun RS, Hutten BA, Kastelein JJ, Stroes ES, Efficacy and safety of high-density lipoprotein cholesterol-increasing compounds: a meta-analysis of randomized controlled trials. J Am Coll Cardiol 2005 45 185 197. doi: 10.1016/j.jacc.2004.10.031.
    • (2005) J Am Coll Cardiol , vol.45 , pp. 185-197
    • Birjmohun, R.S.1    Hutten, B.A.2    Kastelein, J.J.3    Stroes, E.S.4
  • 7
    • 84870045994 scopus 로고    scopus 로고
    • Effects of dalcetrapib in patients with a recent acute coronary syndrome
    • Schwartz GG, Olsson AG, Abt M, dal-OUTCOMES Investigators Effects of dalcetrapib in patients with a recent acute coronary syndrome. N Engl J Med 2012 367 2089 2099. doi: 10.1056/NEJMoa1206797.
    • (2012) N Engl J Med , vol.367 , pp. 2089-2099
    • Schwartz, G.G.1    Olsson, A.G.2    Abt, M.3
  • 8
    • 84864845456 scopus 로고    scopus 로고
    • Plasma HDL cholesterol and risk of myocardial infarction: A Mendelian randomisation study
    • Voight BF, Peloso GM, Orho-Melander M, Plasma HDL cholesterol and risk of myocardial infarction: a Mendelian randomisation study. Lancet 2012 380 572 580. doi: 10.1016/S0140-6736(12)60312-2.
    • (2012) Lancet , vol.380 , pp. 572-580
    • Voight, B.F.1    Peloso, G.M.2    Orho-Melander, M.3
  • 12
    • 0036795589 scopus 로고    scopus 로고
    • Cholesteryl ester flux from HDL to VLDL-1 is preferentially enhanced in type IIB hyperlipidemia in the postprandial state
    • Guerin M, Egger P, Soudant C, Le Goff W, van Tol A, Dupuis R, Chapman MJ, Cholesteryl ester flux from HDL to VLDL-1 is preferentially enhanced in type IIB hyperlipidemia in the postprandial state. J Lipid Res 2002 43 1652 1660
    • (2002) J Lipid Res , vol.43 , pp. 1652-1660
    • Guerin, M.1    Egger, P.2    Soudant, C.3    Le Goff, W.4    Van Tol, A.5    Dupuis, R.6    Chapman, M.J.7
  • 13
    • 0023251133 scopus 로고
    • Accelerated transfer of cholesteryl esters in dyslipidemic plasma. Role of cholesteryl ester transfer protein
    • Tall A, Granot E, Brocia R, Tabas I, Hesler C, Williams K, Denke M, Accelerated transfer of cholesteryl esters in dyslipidemic plasma. Role of cholesteryl ester transfer protein. J Clin Invest 1987 79 1217 1225. doi: 10.1172/JCI112940.
    • (1987) J Clin Invest , vol.79 , pp. 1217-1225
    • Tall, A.1    Granot, E.2    Brocia, R.3    Tabas, I.4    Hesler, C.5    Williams, K.6    Denke, M.7
  • 14
    • 0032777073 scopus 로고    scopus 로고
    • Acute and chronic effects of a 24-hour intravenous triglyceride emulsion challenge on plasma lecithin: Cholesterol acyltransferase, phospholipid transfer protein, and cholesteryl ester transfer protein activities
    • Riemens SC, Van Tol A, Sluiter WJ, Dullaart RP, Acute and chronic effects of a 24-hour intravenous triglyceride emulsion challenge on plasma lecithin: cholesterol acyltransferase, phospholipid transfer protein, and cholesteryl ester transfer protein activities. J Lipid Res 1999 40 1459 1466
    • (1999) J Lipid Res , vol.40 , pp. 1459-1466
    • Riemens, S.C.1    Van Tol, A.2    Sluiter, W.J.3    Dullaart, R.P.4
  • 15
    • 0345396377 scopus 로고
    • Inverse relationship between blood levels of high density lipoprotein subfraction 2 and magnitude of postprandial lipemia
    • Patsch JR, Karlin JB, Scott LW, Smith LC, Gotto AM Jr, Inverse relationship between blood levels of high density lipoprotein subfraction 2 and magnitude of postprandial lipemia. Proc Natl Acad Sci USA 1983 80 1449 1453
    • (1983) Proc Natl Acad Sci USA , vol.80 , pp. 1449-1453
    • Patsch, J.R.1    Karlin, J.B.2    Scott, L.W.3    Smith, L.C.4    Gotto, A.M.5
  • 17
    • 0034746490 scopus 로고    scopus 로고
    • Atherogenic role of elevated CE transfer from HDL to VLDL(1) and dense LDL in type 2 diabetes: Impact of the degree of triglyceridemia
    • Guérin M, Le Goff W, Lassel TS, Van Tol A, Steiner G, Chapman MJ, Atherogenic role of elevated CE transfer from HDL to VLDL(1) and dense LDL in type 2 diabetes: impact of the degree of triglyceridemia. Arterioscler Thromb Vasc Biol 2001 21 282 288
    • (2001) Arterioscler Thromb Vasc Biol , vol.21 , pp. 282-288
    • Guérin, M.1    Le Goff, W.2    Lassel, T.S.3    Van Tol, A.4    Steiner, G.5    Chapman, M.J.6
  • 18
    • 4344665253 scopus 로고    scopus 로고
    • Raising high-density lipoprotein cholesterol with reduction of cardiovascular risk: The role of nicotinic acid-a position paper developed by the European Consensus Panel on HDL-C
    • Chapman MJ, Assmann G, Fruchart JC, Shepherd J, Sirtori C, European Consensus Panel on HDL-C Raising high-density lipoprotein cholesterol with reduction of cardiovascular risk: the role of nicotinic acid-a position paper developed by the European Consensus Panel on HDL-C. Curr Med Res Opin 2004 20 1253 1268. doi: 10.1185/030079904125004402.
    • (2004) Curr Med Res Opin , vol.20 , pp. 1253-1268
    • Chapman, M.J.1    Assmann, G.2    Fruchart, J.C.3    Shepherd, J.4    Sirtori, C.5
  • 20
    • 84900019318 scopus 로고    scopus 로고
    • Effects of extended-release niacin/laropiprant, simvastatin, and the combination on correlations between apolipoprotein B, LDL cholesterol, and non-HDL cholesterol in patients with dyslipidemia
    • Farnier M, Chen E, Johnson-Levonas AO, McCrary Sisk C, Mitchel YB, Effects of extended-release niacin/laropiprant, simvastatin, and the combination on correlations between apolipoprotein B, LDL cholesterol, and non-HDL cholesterol in patients with dyslipidemia. Vasc Health Risk Manag 2014 10 279 290. doi: 10.2147/VHRM.S58694.
    • (2014) Vasc Health Risk Manag , vol.10 , pp. 279-290
    • Farnier, M.1    Chen, E.2    Johnson-Levonas, A.O.3    McCrary Sisk, C.4    Mitchel, Y.B.5
  • 22
    • 37549056925 scopus 로고    scopus 로고
    • Inhibition of CETP by torcetrapib attenuates the atherogenicity of postprandial TG-rich lipoproteins in type IIB hyperlipidemia
    • Guerin M, Le Goff W, Duchene E, Julia Z, Nguyen T, Thuren T, Shear CL, Chapman MJ, Inhibition of CETP by torcetrapib attenuates the atherogenicity of postprandial TG-rich lipoproteins in type IIB hyperlipidemia. Arterioscler Thromb Vasc Biol 2008 28 148 154. doi: 10.1161/ATVBAHA.107.151688.
    • (2008) Arterioscler Thromb Vasc Biol , vol.28 , pp. 148-154
    • Guerin, M.1    Le Goff, W.2    Duchene, E.3    Julia, Z.4    Nguyen, T.5    Thuren, T.6    Shear, C.L.7    Chapman, M.J.8
  • 23
    • 0032853095 scopus 로고    scopus 로고
    • Evidence for a cholesteryl ester donor activity of LDL particles during alimentary lipemia in normolipidemic subjects
    • Lassel TS, Guerin M, Auboiron S, Guy-Grand B, Chapman MJ, Evidence for a cholesteryl ester donor activity of LDL particles during alimentary lipemia in normolipidemic subjects. Atherosclerosis 1999 147 41 48
    • (1999) Atherosclerosis , vol.147 , pp. 41-48
    • Lassel, T.S.1    Guerin, M.2    Auboiron, S.3    Guy-Grand, B.4    Chapman, M.J.5
  • 24
    • 0031964114 scopus 로고    scopus 로고
    • Preferential cholesteryl ester acceptors among triglyceride-rich lipoproteins during alimentary lipemia in normolipidemic subjects
    • Lassel TS, Guérin M, Auboiron S, Chapman MJ, Guy-Grand B, Preferential cholesteryl ester acceptors among triglyceride-rich lipoproteins during alimentary lipemia in normolipidemic subjects. Arterioscler Thromb Vasc Biol 1998 18 65 74
    • (1998) Arterioscler Thromb Vasc Biol , vol.18 , pp. 65-74
    • Lassel, T.S.1    Guérin, M.2    Auboiron, S.3    Chapman, M.J.4    Guy-Grand, B.5
  • 25
    • 0030588599 scopus 로고    scopus 로고
    • Plasma cholesteryl ester transfer protein concentration, high-density lipoprotein cholesterol esterification and transfer rates to lighter density lipoproteins in the fasting state and after a test meal are similar in Type II diabetics and normal controls
    • Lottenberg SA, Lottenberg AM, Nunes VS, McPherson R, Quintão EC, Plasma cholesteryl ester transfer protein concentration, high-density lipoprotein cholesterol esterification and transfer rates to lighter density lipoproteins in the fasting state and after a test meal are similar in Type II diabetics and normal controls. Atherosclerosis 1996 127 81 90
    • (1996) Atherosclerosis , vol.127 , pp. 81-90
    • Lottenberg, S.A.1    Lottenberg, A.M.2    Nunes, V.S.3    McPherson, R.4    Quintão, E.C.5
  • 26
    • 70350220516 scopus 로고    scopus 로고
    • Remnant lipoproteins as strong key particles to atherogenesis
    • Fujioka Y, Ishikawa Y, Remnant lipoproteins as strong key particles to atherogenesis. J Atheroscler Thromb 2009 16 145 154
    • (2009) J Atheroscler Thromb , vol.16 , pp. 145-154
    • Fujioka, Y.1    Ishikawa, Y.2
  • 29
    • 55449114841 scopus 로고    scopus 로고
    • Niacin increases HDL by reducing hepatic expression and plasma levels of cholesteryl ester transfer protein in APOE∗3Leiden.CETP mice
    • van der Hoorn JW, de Haan W, Berbée JF, Havekes LM, Jukema JW, Rensen PC, Princen HM, Niacin increases HDL by reducing hepatic expression and plasma levels of cholesteryl ester transfer protein in APOE∗3Leiden.CETP mice. Arterioscler Thromb Vasc Biol 2008 28 2016 2022. doi: 10.1161/ATVBAHA.108.171363.
    • (2008) Arterioscler Thromb Vasc Biol , vol.28 , pp. 2016-2022
    • Van Der Hoorn, J.W.1    De Haan, W.2    Berbée, J.F.3    Havekes, L.M.4    Jukema, J.W.5    Rensen, P.C.6    Princen, H.M.7
  • 30
    • 37549056925 scopus 로고    scopus 로고
    • Inhibition of CETP by torcetrapib attenuates the atherogenicity of postprandial TG-rich lipoproteins in type IIB hyperlipidemia
    • Guerin M, Le Goff W, Duchene E, Julia Z, Nguyen T, Thuren T, Shear CL, Chapman MJ, Inhibition of CETP by torcetrapib attenuates the atherogenicity of postprandial TG-rich lipoproteins in type IIB hyperlipidemia. Arterioscler Thromb Vasc Biol 2008 28 148 154. doi: 10.1161/ATVBAHA.107.151688.
    • (2008) Arterioscler Thromb Vasc Biol , vol.28 , pp. 148-154
    • Guerin, M.1    Le Goff, W.2    Duchene, E.3    Julia, Z.4    Nguyen, T.5    Thuren, T.6    Shear, C.L.7    Chapman, M.J.8
  • 32
    • 36849037410 scopus 로고    scopus 로고
    • Effects of niacin and Niaspan on HDL lipoprotein cellular SR-BI-mediated cholesterol efflux
    • Morgan JM, de la Llera-Moya M, Capuzzi DM, Effects of niacin and Niaspan on HDL lipoprotein cellular SR-BI-mediated cholesterol efflux. J Clin Lipidol 2007 1 614 619. doi: 10.1016/j.jacl.2007.09.003.
    • (2007) J Clin Lipidol , vol.1 , pp. 614-619
    • Morgan, J.M.1    De La Llera-Moya, M.2    Capuzzi, D.M.3
  • 33
    • 1542283778 scopus 로고    scopus 로고
    • Formation and metabolism of prebeta-migrating, lipid-poor apolipoprotein A-I
    • Rye KA, Barter PJ, Formation and metabolism of prebeta-migrating, lipid-poor apolipoprotein A-I. Arterioscler Thromb Vasc Biol 2004 24 421 428. doi: 10.1161/01.ATV.0000104029.74961.f5.
    • (2004) Arterioscler Thromb Vasc Biol , vol.24 , pp. 421-428
    • Rye, K.A.1    Barter, P.J.2
  • 35
    • 33646558306 scopus 로고    scopus 로고
    • Relative contributions of ABCA1 and SR-BI to cholesterol efflux to serum from fibroblasts and macrophages
    • Duong M, Collins HL, Jin W, Zanotti I, Favari E, Rothblat GH, Relative contributions of ABCA1 and SR-BI to cholesterol efflux to serum from fibroblasts and macrophages. Arterioscler Thromb Vasc Biol 2006 26 541 547. doi: 10.1161/01.ATV.0000203515.25574.19.
    • (2006) Arterioscler Thromb Vasc Biol , vol.26 , pp. 541-547
    • Duong, M.1    Collins, H.L.2    Jin, W.3    Zanotti, I.4    Favari, E.5    Rothblat, G.H.6
  • 36
    • 84885844867 scopus 로고    scopus 로고
    • The addition of niacin to statin therapy improves high-density lipoprotein cholesterol levels but not metrics of functionality
    • Khera AV, Patel PJ, Reilly MP, Rader DJ, The addition of niacin to statin therapy improves high-density lipoprotein cholesterol levels but not metrics of functionality. J Am Coll Cardiol 2013 62 1909 1910. doi: 10.1016/j.jacc.2013.07.025.
    • (2013) J Am Coll Cardiol , vol.62 , pp. 1909-1910
    • Khera, A.V.1    Patel, P.J.2    Reilly, M.P.3    Rader, D.J.4
  • 37
    • 1842582603 scopus 로고    scopus 로고
    • Scavenger receptor class B type I-mediated cholesteryl ester-selective uptake and efflux of unesterified cholesterol. Influence of high density lipoprotein size and structure
    • Thuahnai ST, Lund-Katz S, Dhanasekaran P, de la Llera-Moya M, Connelly MA, Williams DL, Rothblat GH, Phillips MC, Scavenger receptor class B type I-mediated cholesteryl ester-selective uptake and efflux of unesterified cholesterol. Influence of high density lipoprotein size and structure. J Biol Chem 2004 279 12448 12455. doi: 10.1074/jbc.M311718200.
    • (2004) J Biol Chem , vol.279 , pp. 12448-12455
    • Thuahnai, S.T.1    Lund-Katz, S.2    Dhanasekaran, P.3    De La Llera-Moya, M.4    Connelly, M.A.5    Williams, D.L.6    Rothblat, G.H.7    Phillips, M.C.8
  • 39
    • 44649111054 scopus 로고    scopus 로고
    • Niacin inhibits surface expression of ATP synthase beta chain in HepG2 cells: Implications for raising HDL
    • Zhang LH, Kamanna VS, Zhang MC, Kashyap ML, Niacin inhibits surface expression of ATP synthase beta chain in HepG2 cells: implications for raising HDL. J Lipid Res 2008 49 1195 1201. doi: 10.1194/jlr.M700426-JLR200.
    • (2008) J Lipid Res , vol.49 , pp. 1195-1201
    • Zhang, L.H.1    Kamanna, V.S.2    Zhang, M.C.3    Kashyap, M.L.4
  • 41
    • 24944558128 scopus 로고    scopus 로고
    • ACAT2 contributes cholesteryl esters to newly secreted VLDL, whereas LCAT adds cholesteryl ester to LDL in mice
    • Lee RG, Shah R, Sawyer JK, Hamilton RL, Parks JS, Rudel LL, ACAT2 contributes cholesteryl esters to newly secreted VLDL, whereas LCAT adds cholesteryl ester to LDL in mice. J Lipid Res 2005 46 1205 1212. doi: 10.1194/jlr.M500018-JLR200.
    • (2005) J Lipid Res , vol.46 , pp. 1205-1212
    • Lee, R.G.1    Shah, R.2    Sawyer, J.K.3    Hamilton, R.L.4    Parks, J.S.5    Rudel, L.L.6
  • 42
    • 84861606700 scopus 로고    scopus 로고
    • Niacin and statin combination therapy for atherosclerosis regression and prevention of cardiovascular disease events: Reconciling the AIM-HIGH (Atherothrombosis Intervention in Metabolic Syndrome with Low HDL/High Triglycerides: Impact on Global Health Outcomes) trial with previous surrogate endpoint trials
    • Michos ED, Sibley CT, Baer JT, Blaha MJ, Blumenthal RS, Niacin and statin combination therapy for atherosclerosis regression and prevention of cardiovascular disease events: reconciling the AIM-HIGH (Atherothrombosis Intervention in Metabolic Syndrome With Low HDL/High Triglycerides: Impact on Global Health Outcomes) trial with previous surrogate endpoint trials. J Am Coll Cardiol 2012 59 2058 2064. doi: 10.1016/j.jacc.2012.01.045.
    • (2012) J Am Coll Cardiol , vol.59 , pp. 2058-2064
    • Michos, E.D.1    Sibley, C.T.2    Baer, J.T.3    Blaha, M.J.4    Blumenthal, R.S.5
  • 44
    • 34447520136 scopus 로고    scopus 로고
    • Fasting compared with nonfasting triglycerides and risk of cardiovascular events in women
    • Bansal S, Buring JE, Rifai N, Mora S, Sacks FM, Ridker PM, Fasting compared with nonfasting triglycerides and risk of cardiovascular events in women. JAMA 2007 298 309 316. doi: 10.1001/jama.298.3.309.
    • (2007) JAMA , vol.298 , pp. 309-316
    • Bansal, S.1    Buring, J.E.2    Rifai, N.3    Mora, S.4    Sacks, F.M.5    Ridker, P.M.6


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